Mov10 like RISC complex RNA helicase 1

AltitudeomicsDB
Protein Official symbol
Aliases MOV10L1
Chromosomal Location
Length 1211
Uniprot ID Q9BXT6
EC number 3.6.4.13
Protein family Information(Pfam) PF13086;PF13087;
PDB id None
InterPro ID IPR041679;IPR041677;IPR027417;
dbSNP rs12628964 rs9617066 rs3810971 rs760749 rs2340601 rs3736689 rs2272837 rs2272843

Protein Protein Interaction

0%
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AltitudeomicsDB
Protein 1 Protein 2 Combine Score
Gene Ontology Semantic Similarity
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# 9871 (SEC24D) 9632 (SEC24C) 5537 (PPP6C) 55291 (PPP6R3) 23243 (ANKRD28) 10802 (SEC24A) 261726 (TIPRL) 3476 (IGBP1) 5524 (PPP2R4) 91526 (ANKRD44) 22870 (PPP6R1) 9701 (PPP6R2) 10427 (SEC24B)
9871 (SEC24D) 1.00 1.00 0.65 0.75 1.00 0.96 1.00 0.64 0.50 1.00 0.70 1.00 0.96
9632 (SEC24C) 1.00 1.00 0.65 0.75 1.00 0.96 1.00 0.64 0.50 1.00 0.70 1.00 0.96
5537 (PPP6C) 0.65 0.65 1.00 0.68 1.00 0.61 1.00 0.57 0.47 1.00 0.64 1.00 0.61
55291 (PPP6R3) 0.75 0.75 0.68 1.00 1.00 0.73 1.00 0.78 0.55 1.00 0.90 1.00 0.73
23243 (ANKRD28) 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00
10802 (SEC24A) 0.96 0.96 0.61 0.73 1.00 1.00 1.00 0.61 0.48 1.00 0.68 1.00 1.00
261726 (TIPRL) 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00
3476 (IGBP1) 0.64 0.64 0.57 0.78 1.00 0.61 1.00 1.00 0.71 1.00 0.74 1.00 0.61
5524 (PPP2R4) 0.50 0.50 0.47 0.55 1.00 0.48 1.00 0.71 1.00 1.00 0.55 1.00 0.48
91526 (ANKRD44) 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00
22870 (PPP6R1) 0.70 0.70 0.64 0.90 1.00 0.68 1.00 0.74 0.55 1.00 1.00 1.00 0.68
9701 (PPP6R2) 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00
10427 (SEC24B) 0.96 0.96 0.61 0.73 1.00 1.00 1.00 0.61 0.48 1.00 0.68 1.00 1.00
Association with High Altitude
Protein Official symbol Source Organism Tissue of Expression Level of hypoxia Altitude Duration of experiment Level of expression Fold change Experiment details geographical location ethnicity of the patients Control group Control (Fold change) Reference (PMID)
MOV10L1 Rat Left brain cortices 300hPa 9144 m 1 hour upregulated 1.34±0.1 TMT labeled LTQ orbitrap Southwestern europe Male wistar rats 1 Adult male Wistar rats weighing 350 g 28697276
Association with TF
TF TF Entrez Gene Gene Entrez Type PMID Database
Association with miRNA
miRTarBase ID miRNA Species (miRNA) Protein Official Symbol Human Entrez ID Species (Target Gene) Experiments Support Type References (PMID)
Gene Ontology
ID GO ID GO Term GO Type
300141 GO:0007141 male meiosis I GOTERM_BP_DIRECT
300141 GO:0007517 muscle organ development GOTERM_BP_DIRECT
300141 GO:0007281 germ cell development GOTERM_BP_DIRECT
300141 GO:0043046 DNA methylation involved in gamete generation GOTERM_BP_DIRECT
300141 GO:0007283 spermatogenesis GOTERM_BP_DIRECT
300141 GO:0034587 piRNA metabolic process GOTERM_BP_DIRECT
300141 GO:0004004 adenine phosphoribosyltransferase activity GOTERM_MF_DIRECT
300141 GO:0034584 protein kinase A catalytic subunit binding GOTERM_MF_DIRECT
300141 GO:0008283 cell proliferation GOTERM_BP_DIRECT
300141 GO:0045786 negative regulation of cell cycle GOTERM_BP_DIRECT
300141 GO:0071546 pi-body GOTERM_CC_DIRECT
300141 GO:0043186 P granule GOTERM_CC_DIRECT
300141 GO:0007140 male meiosis GOTERM_BP_DIRECT
Pathways
Human Entrez ID KEGG ID KEGG Term
Association with Disease
Protein Official Symbol Human Entrez ID Disease Name Disease Id Disease Semantic Type Semantic score DSI DPI Disease Type
Association with Drug
Protein Official Symbol Human Entrez ID drug_claim_primary_name drug_name drug_chembl_id interaction_types