Ig alpha 1 chain c region
AltitudeomicsDB
| Protein Official symbol |
|
| Aliases |
IGHA1 |
| Chromosomal Location |
|
| Length |
353 |
| Uniprot ID |
P01876 |
| EC number |
None |
| Protein family Information(Pfam) |
PF07654; |
| PDB id |
1IGA;1OW0;2ESG;2QEJ;3CHN;6UE7; |
| InterPro ID |
IPR007110;IPR036179;IPR013783;IPR003006;IPR003597; |
| dbSNP |
rs1407 |
AltitudeomicsDB
| Protein 1 |
Protein 2 |
Combine Score |
Association with High Altitude
| Protein Official symbol |
Source Organism |
Tissue of Expression |
Level of hypoxia |
Altitude |
Duration of experiment |
Level of expression |
Fold change |
Experiment details |
geographical location |
ethnicity of the patients |
Control group |
Control (Fold change) |
Reference (PMID) |
| IGHA1 |
Human |
Saliva |
- |
4175 m |
7 day |
upregulated |
0.09 |
2-DE |
Himalayas |
Indians |
1.76 |
Individuals residing at sea level |
30219637 |
Association with TF
| TF |
TF Entrez |
Gene |
Gene Entrez |
Type |
PMID |
Database |
Association with miRNA
| miRTarBase ID |
miRNA |
Species (miRNA) |
Protein Official Symbol |
Human Entrez ID |
Species (Target Gene) |
Experiments |
Support Type |
References (PMID) |
Gene Ontology
| ID |
GO ID |
GO Term |
GO Type |
| 3493 |
GO:0003094 |
glomerular filtration |
GOTERM_BP_DIRECT |
| 3493 |
GO:0006958 |
complement activation |
GOTERM_BP_DIRECT |
| 3493 |
GO:0060267 |
positive regulation of respiratory burst |
GOTERM_BP_DIRECT |
| 3493 |
GO:0071752 |
secretory dimeric IgA immunoglobulin complex |
GOTERM_CC_DIRECT |
| 3493 |
GO:0006910 |
phagocytosis |
GOTERM_BP_DIRECT |
| 3493 |
GO:0009897 |
external side of plasma membrane |
GOTERM_CC_DIRECT |
| 3493 |
GO:0001895 |
retina homeostasis |
GOTERM_BP_DIRECT |
| 3493 |
GO:0071751 |
secretory IgA immunoglobulin complex |
GOTERM_CC_DIRECT |
| 3493 |
GO:0018298 |
protein-chromophore linkage |
GOTERM_BP_DIRECT |
| 3493 |
GO:0019731 |
antibacterial humoral response |
GOTERM_BP_DIRECT |
| 3493 |
GO:0045087 |
innate immune response |
GOTERM_BP_DIRECT |
| 3493 |
GO:0005576 |
extracellular region |
GOTERM_CC_DIRECT |
| 3493 |
GO:0070062 |
extracellular exosome |
GOTERM_CC_DIRECT |
| 3493 |
GO:0006955 |
immune response |
GOTERM_BP_DIRECT |
| 3493 |
GO:0005615 |
extracellular space |
GOTERM_CC_DIRECT |
| 3493 |
GO:0071748 |
monomeric IgA immunoglobulin complex |
GOTERM_CC_DIRECT |
| 3493 |
GO:0034987 |
retinol transporter activity |
GOTERM_MF_DIRECT |
| 3493 |
GO:0072562 |
blood microparticle |
GOTERM_CC_DIRECT |
| 3493 |
GO:0003823 |
protein-glutamine gamma-glutamyltransferase activity |
GOTERM_MF_DIRECT |
| 3493 |
GO:0006898 |
receptor-mediated endocytosis |
GOTERM_BP_DIRECT |
| 3493 |
GO:0050853 |
B cell receptor signaling pathway |
GOTERM_BP_DIRECT |
| 3493 |
GO:0050871 |
positive regulation of B cell activation |
GOTERM_BP_DIRECT |
| 3493 |
GO:0006911 |
phagocytosis |
GOTERM_BP_DIRECT |
Pathways
| Human Entrez ID |
KEGG ID |
KEGG Term |
Association with Disease
| Protein Official Symbol |
Human Entrez ID |
Disease Name |
Disease Id |
Disease Semantic Type |
Semantic score |
DSI |
DPI |
Disease Type |
Association with Drug
| Protein Official Symbol |
Human Entrez ID |
drug_claim_primary_name |
drug_name |
drug_chembl_id |
interaction_types |