Mitochondrial ornithine transporter 2 (Solute carrier family 25 member 2)

AltitudeomicsDB
Protein Official symbol SLC25A2
Aliases SLC25A2 ORNT2
Chromosomal Location 5
Length 301
Uniprot ID Q9BXI2
EC number None
Protein family Information(Pfam) PF00153;
PDB id None
InterPro ID IPR018108;IPR023395;
dbSNP rs10075302 rs3749779 rs3749780

Protein Protein Interaction

0%
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AltitudeomicsDB
Protein 1 Protein 2 Combine Score
TAF7 SLC25A2 0.555
PCDHGB4 SLC25A2 0.555
OAT SLC25A2 0.548
Gene Ontology Semantic Similarity
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# 6879 (TAF7) 4942 (OAT)
6879 (TAF7) 1.00 0.21
4942 (OAT) 0.21 1.00
Association with High Altitude
Protein Official symbol Source Organism Tissue of Expression Level of hypoxia Altitude Duration of experiment Level of expression Fold change Experiment details geographical location ethnicity of the patients Control group Control (Fold change) Reference (PMID)
SLC25A2 Toad Heart - 3464 m 33 day downregulated -2.894691635 RNA-seq Tibetan Plateau Asiatic toad 1 Zoige (High altitute Toad) Vs Chengdu (Low altitude toad) - 28673260
Association with TF
TF TF Entrez Gene Gene Entrez Type PMID Database
Association with miRNA
miRTarBase ID miRNA Species (miRNA) Protein Official Symbol Human Entrez ID Species (Target Gene) Experiments Support Type References (PMID)
MIRT043873 hsa-miR-378a-3p Homo sapiens SLC25A2 83884 Homo sapiens CLASH Functional MTI (Weak) 23622248
MIRT667098 hsa-miR-548s Homo sapiens SLC25A2 83884 Homo sapiens HITS-CLIP Functional MTI (Weak) 23824327
MIRT667104 hsa-miR-6771-3p Homo sapiens SLC25A2 83884 Homo sapiens HITS-CLIP Functional MTI (Weak) 23824327
MIRT667105 hsa-miR-548c-3p Homo sapiens SLC25A2 83884 Homo sapiens HITS-CLIP Functional MTI (Weak) 23824327
MIRT667101 hsa-miR-3190-5p Homo sapiens SLC25A2 83884 Homo sapiens HITS-CLIP Functional MTI (Weak) 23824327
MIRT667103 hsa-miR-6849-3p Homo sapiens SLC25A2 83884 Homo sapiens HITS-CLIP Functional MTI (Weak) 23824327
MIRT667100 hsa-miR-4786-5p Homo sapiens SLC25A2 83884 Homo sapiens HITS-CLIP Functional MTI (Weak) 23824327
MIRT667102 hsa-miR-6728-3p Homo sapiens SLC25A2 83884 Homo sapiens HITS-CLIP Functional MTI (Weak) 23824327
MIRT667099 hsa-miR-3926 Homo sapiens SLC25A2 83884 Homo sapiens HITS-CLIP Functional MTI (Weak) 23824327
Gene Ontology
ID GO ID GO Term GO Type
83884 GO:0000050 urea cycle GOTERM_BP_DIRECT
83884 GO:0003735 structural constituent of ribosome GOTERM_MF_DIRECT
83884 GO:1903352 L-ornithine transmembrane transport GOTERM_BP_DIRECT
83884 GO:0000064 fatty-acyl-CoA binding GOTERM_MF_DIRECT
83884 GO:0005743 mitochondrial inner membrane GOTERM_CC_DIRECT
83884 GO:0006412 translation GOTERM_BP_DIRECT
83884 GO:0016021 integral component of membrane GOTERM_CC_DIRECT
Pathways
Human Entrez ID KEGG ID KEGG Term
Association with Disease
Protein Official Symbol Human Entrez ID Disease Name Disease Id Disease Semantic Type Semantic score DSI DPI Disease Type
Association with Drug
Protein Official Symbol Human Entrez ID drug_claim_primary_name drug_name drug_chembl_id interaction_types