#node1 node2 node1_string_internal_id node2_string_internal_id node1_external_id node2_external_id neighborhood_on_chromosome gene_fusion phylogenetic_cooccurrence homology coexpression experimentally_determined_interaction database_annotated automated_textmining combined_score AKT1 MTOR 4450372 4442490 9606.ENSP00000451828 9606.ENSP00000354558 0 0 0.0 0.0 0.08 0 0.9 0.972 0.997 LEPR LEP 4440182 4438805 9606.ENSP00000330393 9606.ENSP00000312652 0 0 0.0 0.0 0.0 0 0.9 0.972 0.997 EGFR EGF 4436186 4435570 9606.ENSP00000275493 9606.ENSP00000265171 0 0 0.0 0.0 0.16 0 0.9 0.972 0.997 IL10 IL6 4448642 4447254 9606.ENSP00000412237 9606.ENSP00000385675 0 0 0.0 0.0 0.077 0 0.9 0.974 0.997 JAK2 STAT3 4445579 4435468 9606.ENSP00000371067 9606.ENSP00000264657 0 0 0.0 0.0 0.055 0 0.9 0.979 0.997 IL6 STAT3 4447254 4435468 9606.ENSP00000385675 9606.ENSP00000264657 0 0 0.0 0.0 0.0 0 0.9 0.97 0.996 IL10 CXCL8 4448642 4438229 9606.ENSP00000412237 9606.ENSP00000306512 0 0 0.0 0.0 0.061 0 0.9 0.962 0.996 BCL2L1 TP53 4437866 4435880 9606.ENSP00000302564 9606.ENSP00000269305 0 0 0.0 0.0 0.05 0 0.9 0.967 0.996 IL6 IL4 4447254 4433533 9606.ENSP00000385675 9606.ENSP00000231449 0 0 0.0 0.0 0.0 0 0.9 0.968 0.996 SOX2 NANOG 4439616 4433459 9606.ENSP00000323588 9606.ENSP00000229307 0 0 0.0 0.0 0.136 0 0.9 0.966 0.996 IL10 CCL2 4448642 4433339 9606.ENSP00000412237 9606.ENSP00000225831 0 0 0.0 0.0 0.0 0 0.9 0.955 0.995 SOCS3 STAT3 4440175 4435468 9606.ENSP00000330341 9606.ENSP00000264657 0 0 0.0 0.0 0.103 0 0.9 0.954 0.995 VEGFA HIF1A 4451310 4449842 9606.ENSP00000478570 9606.ENSP00000437955 0 0 0.0 0.0 0.062 0 0.9 0.947 0.994 IL6 IL6R 4447254 4443110 9606.ENSP00000385675 9606.ENSP00000357470 0 0 0.0 0.0 0.0 0 0.9 0.945 0.994 JAK1 STAT3 4441317 4435468 9606.ENSP00000343204 9606.ENSP00000264657 0 0 0.0 0.0 0.096 0 0.9 0.948 0.994 IL10 STAT3 4448642 4435468 9606.ENSP00000412237 9606.ENSP00000264657 0 0 0.0 0.0 0.0 0 0.9 0.933 0.993 IL10 CSF2 4448642 4437349 9606.ENSP00000412237 9606.ENSP00000296871 0 0 0.0 0.0 0.061 0 0.9 0.937 0.993 AKT1 STAT3 4450372 4435468 9606.ENSP00000451828 9606.ENSP00000264657 0 0 0.0 0.0 0.0 0 0.9 0.938 0.993 AKT1 TP53 4450372 4435880 9606.ENSP00000451828 9606.ENSP00000269305 0 0 0.0 0.0 0.054 0 0.9 0.941 0.993 VEGFA EGF 4451310 4435570 9606.ENSP00000478570 9606.ENSP00000265171 0 0 0.0 0.0 0.0 0 0.9 0.937 0.993 BCL6 TP53 4447113 4435880 9606.ENSP00000384371 9606.ENSP00000269305 0 0 0.0 0.0 0.0 0 0.9 0.929 0.992 LEP STAT3 4438805 4435468 9606.ENSP00000312652 9606.ENSP00000264657 0 0 0.0 0.0 0.0 0 0.9 0.928 0.992 IL6 SOCS3 4447254 4440175 9606.ENSP00000385675 9606.ENSP00000330341 0 0 0.0 0.0 0.207 0 0.9 0.917 0.992 EGFR STAT3 4436186 4435468 9606.ENSP00000275493 9606.ENSP00000264657 0 0 0.0 0.0 0.0 0 0.9 0.927 0.992 CXCL8 IL4 4438229 4433533 9606.ENSP00000306512 9606.ENSP00000231449 0 0 0.0 0.0 0.0 0 0.9 0.927 0.992 VEGFA STAT3 4451310 4435468 9606.ENSP00000478570 9606.ENSP00000264657 0 0 0.0 0.0 0.0 0 0.9 0.916 0.991 IL17A STAT3 4441397 4435468 9606.ENSP00000344192 9606.ENSP00000264657 0 0 0.0 0.0 0.0 0 0.9 0.916 0.991 MYC AKT1 4451407 4450372 9606.ENSP00000479618 9606.ENSP00000451828 0 0 0.0 0.0 0.052 0 0.9 0.915 0.991 IL4 CCL2 4433533 4433339 9606.ENSP00000231449 9606.ENSP00000225831 0 0 0.0 0.0 0.0 0 0.9 0.918 0.991 BCL2L1 STAT3 4437866 4435468 9606.ENSP00000302564 9606.ENSP00000264657 0 0 0.0 0.0 0.0 0 0.9 0.916 0.991 SRC STAT3 4444215 4435468 9606.ENSP00000362680 9606.ENSP00000264657 0 0 0.0 0.0 0.058 0 0.9 0.92 0.991 AKT1 BCL2L1 4450372 4437866 9606.ENSP00000451828 9606.ENSP00000302564 0 0 0.0 0.0 0.073 0 0.9 0.902 0.99 JAK3 STAT3 4447709 4435468 9606.ENSP00000391676 9606.ENSP00000264657 0 0 0.0 0.0 0.062 0 0.9 0.906 0.99 BCL6 IRF4 4447113 4445477 9606.ENSP00000384371 9606.ENSP00000370343 0 0 0.0 0.0 0.061 0 0.9 0.911 0.99 JAK2 SOCS3 4445579 4440175 9606.ENSP00000371067 9606.ENSP00000330341 0 0 0.0 0.0 0.062 0 0.9 0.906 0.99 SRC EGF 4444215 4435570 9606.ENSP00000362680 9606.ENSP00000265171 0 0 0.0 0.0 0.0 0 0.9 0.909 0.99 SOCS3 LEP 4440175 4438805 9606.ENSP00000330341 9606.ENSP00000312652 0 0 0.0 0.0 0.062 0 0.9 0.901 0.989 VEGFA MMP9 4451310 4443919 9606.ENSP00000478570 9606.ENSP00000361405 0 0 0.0 0.0 0.0 0 0.8 0.946 0.989 STAT3 CCND1 4435468 4433391 9606.ENSP00000264657 9606.ENSP00000227507 0 0 0.0 0.0 0.049 0 0.9 0.894 0.989 IL6 IL13 4447254 4438088 9606.ENSP00000385675 9606.ENSP00000304915 0 0 0.0 0.0 0.0 0 0.9 0.893 0.988 PTPN11 MAPK3 4441096 4435180 9606.ENSP00000340944 9606.ENSP00000263025 0 0 0.0 0.0 0.067 0 0.9 0.872 0.987 IL6R STAT3 4443110 4435468 9606.ENSP00000357470 9606.ENSP00000264657 0 0 0.0 0.0 0.062 0 0.9 0.878 0.987 VEGFA SRC 4451310 4444215 9606.ENSP00000478570 9606.ENSP00000362680 0 0 0.0 0.0 0.065 0 0.9 0.881 0.987 TP53 STAT3 4435880 4435468 9606.ENSP00000269305 9606.ENSP00000264657 0 0 0.0 0.0 0.0 0 0.9 0.87 0.986 TYK2 STAT3 4449608 4435468 9606.ENSP00000431885 9606.ENSP00000264657 0 0 0.0 0.0 0.061 0 0.9 0.872 0.986 STAT3 NANOG 4435468 4433459 9606.ENSP00000264657 9606.ENSP00000229307 0 0 0.0 0.0 0.0 0 0.9 0.872 0.986 FGF2 NANOG 4435443 4433459 9606.ENSP00000264498 9606.ENSP00000229307 0 0 0.0 0.0 0.0 0 0.9 0.871 0.986 JAK2 SOCS1 4445579 4440100 9606.ENSP00000371067 9606.ENSP00000329418 0 0 0.0 0.0 0.057 0 0.9 0.857 0.985 MYC STAT3 4451407 4435468 9606.ENSP00000479618 9606.ENSP00000264657 0 0 0.0 0.0 0.0 0 0.9 0.859 0.985 IL6 CXCL8 4447254 4438229 9606.ENSP00000385675 9606.ENSP00000306512 0 0 0.0 0.0 0.581 0 0.0 0.966 0.985 PTPN11 STAT3 4441096 4435468 9606.ENSP00000340944 9606.ENSP00000264657 0 0 0.0 0.0 0.062 0 0.9 0.853 0.985 MCL1 STAT3 4443243 4435468 9606.ENSP00000358022 9606.ENSP00000264657 0 0 0.0 0.0 0.064 0 0.9 0.854 0.985 LEPR STAT3 4440182 4435468 9606.ENSP00000330393 9606.ENSP00000264657 0 0 0.0 0.0 0.0 0 0.9 0.859 0.985 FOS MAPK3 4438204 4435180 9606.ENSP00000306245 9606.ENSP00000263025 0 0 0.0 0.0 0.0 0 0.9 0.847 0.984 MTOR EGFR 4442490 4436186 9606.ENSP00000354558 9606.ENSP00000275493 0 0 0.0 0.0 0.061 0 0.9 0.843 0.984 JAK2 PTPN11 4445579 4441096 9606.ENSP00000371067 9606.ENSP00000340944 0 0 0.0 0.0 0.062 0 0.9 0.849 0.984 FOS MAPK1 4438204 4432880 9606.ENSP00000306245 9606.ENSP00000215832 0 0 0.0 0.0 0.0 0 0.9 0.852 0.984 EGF STAT3 4435570 4435468 9606.ENSP00000265171 9606.ENSP00000264657 0 0 0.0 0.0 0.0 0 0.9 0.853 0.984 JAK2 LEP 4445579 4438805 9606.ENSP00000371067 9606.ENSP00000312652 0 0 0.0 0.0 0.0 0 0.9 0.846 0.984 PTPN11 EGFR 4441096 4436186 9606.ENSP00000340944 9606.ENSP00000275493 0 0 0.0 0.0 0.0 0 0.9 0.852 0.984 CXCL8 IL13 4438229 4438088 9606.ENSP00000306512 9606.ENSP00000304915 0 0 0.0 0.0 0.0 0 0.9 0.839 0.983 SOCS1 STAT3 4440100 4435468 9606.ENSP00000329418 9606.ENSP00000264657 0 0 0.0 0.0 0.0 0 0.9 0.844 0.983 LEPR SOCS3 4440182 4440175 9606.ENSP00000330393 9606.ENSP00000330341 0 0 0.0 0.0 0.0 0 0.9 0.838 0.983 JAK2 LEPR 4445579 4440182 9606.ENSP00000371067 9606.ENSP00000330393 0 0 0.0 0.0 0.0 0 0.9 0.841 0.983 SOX2 FGF2 4439616 4435443 9606.ENSP00000323588 9606.ENSP00000264498 0 0 0.0 0.0 0.069 0 0.9 0.832 0.983 PTPN11 MAPK1 4441096 4432880 9606.ENSP00000340944 9606.ENSP00000215832 0 0 0.0 0.0 0.099 0 0.9 0.832 0.983 STAT3 MAPK1 4435468 4432880 9606.ENSP00000264657 9606.ENSP00000215832 0 0 0.0 0.0 0.06 0 0.9 0.837 0.983 CXCL8 STAT3 4438229 4435468 9606.ENSP00000306512 9606.ENSP00000264657 0 0 0.0 0.0 0.0 0 0.9 0.838 0.983 IL22 STAT3 4450035 4435468 9606.ENSP00000442424 9606.ENSP00000264657 0 0 0.0 0.0 0.0 0 0.9 0.837 0.983 RAC1 STAT3 4441834 4435468 9606.ENSP00000348461 9606.ENSP00000264657 0 0 0.0 0.0 0.0 0 0.9 0.846 0.983 IL6 FOS 4447254 4438204 9606.ENSP00000385675 9606.ENSP00000306245 0 0 0.0 0.0 0.088 0 0.9 0.819 0.982 MTOR STAT3 4442490 4435468 9606.ENSP00000354558 9606.ENSP00000264657 0 0 0.0 0.0 0.049 0 0.9 0.835 0.982 SOX2 STAT3 4439616 4435468 9606.ENSP00000323588 9606.ENSP00000264657 0 0 0.0 0.0 0.0 0 0.9 0.836 0.982 IL6 MAPK1 4447254 4432880 9606.ENSP00000385675 9606.ENSP00000215832 0 0 0.0 0.0 0.0 0 0.9 0.834 0.982 STAT3 OSM 4435468 4432875 9606.ENSP00000264657 9606.ENSP00000215781 0 0 0.0 0.0 0.0 0 0.9 0.833 0.982 IL6 CCL2 4447254 4433339 9606.ENSP00000385675 9606.ENSP00000225831 0 0 0.0 0.0 0.267 0 0.0 0.977 0.982 IL23R STAT3 4439435 4435468 9606.ENSP00000321345 9606.ENSP00000264657 0 0 0.0 0.0 0.0 0 0.9 0.831 0.982 POMC STAT3 4447072 4435468 9606.ENSP00000384092 9606.ENSP00000264657 0 0 0.0 0.0 0.0 0 0.9 0.831 0.982 AKT1 HIF1A 4450372 4449842 9606.ENSP00000451828 9606.ENSP00000437955 0 0 0.0 0.0 0.0 0 0.9 0.827 0.982 STAT3 MAPK3 4435468 4435180 9606.ENSP00000264657 9606.ENSP00000263025 0 0 0.0 0.0 0.06 0 0.9 0.815 0.981 TYK2 IL10RB 4449608 4436842 9606.ENSP00000431885 9606.ENSP00000290200 0 0 0.0 0.0 0.0 0 0.9 0.82 0.981 IL13 CCL2 4438088 4433339 9606.ENSP00000304915 9606.ENSP00000225831 0 0 0.0 0.0 0.0 0 0.9 0.822 0.981 MMP9 STAT3 4443919 4435468 9606.ENSP00000361405 9606.ENSP00000264657 0 0 0.0 0.0 0.0 0 0.9 0.824 0.981 STAT3 CCL2 4435468 4433339 9606.ENSP00000264657 9606.ENSP00000225831 0 0 0.0 0.0 0.0 0 0.9 0.824 0.981 STAT3 IL4 4435468 4433533 9606.ENSP00000264657 9606.ENSP00000231449 0 0 0.0 0.0 0.0 0 0.9 0.817 0.98 BCL6 STAT3 4447113 4435468 9606.ENSP00000384371 9606.ENSP00000264657 0 0 0.0 0.0 0.0 0 0.9 0.816 0.98 STAT3 FGF2 4435468 4435443 9606.ENSP00000264657 9606.ENSP00000264498 0 0 0.0 0.0 0.0 0 0.9 0.808 0.98 FOS STAT3 4438204 4435468 9606.ENSP00000306245 9606.ENSP00000264657 0 0 0.0 0.0 0.0 0 0.9 0.811 0.98 PTGS2 STAT3 4442894 4435468 9606.ENSP00000356438 9606.ENSP00000264657 0 0 0.0 0.0 0.0 0 0.9 0.81 0.98 STAT3 MMP2 4435468 4433061 9606.ENSP00000264657 9606.ENSP00000219070 0 0 0.0 0.0 0.0 0 0.9 0.799 0.979 IL6ST STAT3 4445526 4435468 9606.ENSP00000370698 9606.ENSP00000264657 0 0 0.0 0.0 0.063 0 0.9 0.797 0.979 STAT3 IL21 4435468 4435442 9606.ENSP00000264657 9606.ENSP00000264497 0 0 0.0 0.0 0.0 0 0.9 0.804 0.979 CSF2 STAT3 4437349 4435468 9606.ENSP00000296871 9606.ENSP00000264657 0 0 0.0 0.0 0.0 0 0.9 0.805 0.979 IRF4 STAT3 4445477 4435468 9606.ENSP00000370343 9606.ENSP00000264657 0 0 0.0 0.0 0.0 0 0.9 0.805 0.979 VEGFA EGFR 4451310 4436186 9606.ENSP00000478570 9606.ENSP00000275493 0 0 0.0 0.0 0.089 0 0.6 0.947 0.979 SRC MMP9 4444215 4443919 9606.ENSP00000362680 9606.ENSP00000361405 0 0 0.0 0.0 0.088 0 0.9 0.796 0.979 IL10RB STAT3 4436842 4435468 9606.ENSP00000290200 9606.ENSP00000264657 0 0 0.0 0.0 0.076 0 0.9 0.792 0.979 VEGFA MMP2 4451310 4433061 9606.ENSP00000478570 9606.ENSP00000219070 0 0 0.0 0.0 0.065 0 0.8 0.899 0.979 IL17F STAT3 4440787 4435468 9606.ENSP00000337432 9606.ENSP00000264657 0 0 0.0 0.0 0.0 0 0.9 0.797 0.978 IL13 STAT3 4438088 4435468 9606.ENSP00000304915 9606.ENSP00000264657 0 0 0.0 0.0 0.0 0 0.9 0.792 0.978 MYC MAPK1 4451407 4432880 9606.ENSP00000479618 9606.ENSP00000215832 0 0 0.0 0.0 0.0 0 0.9 0.798 0.978 JAK1 IL4 4441317 4433533 9606.ENSP00000343204 9606.ENSP00000231449 0 0 0.0 0.0 0.0 0 0.9 0.792 0.978 PTPN11 SOCS3 4441096 4440175 9606.ENSP00000340944 9606.ENSP00000330341 0 0 0.0 0.0 0.062 0 0.9 0.783 0.977 IL10 JAK1 4448642 4441317 9606.ENSP00000412237 9606.ENSP00000343204 0 0 0.0 0.0 0.0 0 0.9 0.781 0.977 BCL2L1 MAPK1 4437866 4432880 9606.ENSP00000302564 9606.ENSP00000215832 0 0 0.0 0.0 0.0 0 0.9 0.786 0.977 HIF1A STAT3 4449842 4435468 9606.ENSP00000437955 9606.ENSP00000264657 0 0 0.0 0.0 0.061 0 0.9 0.781 0.977 JAK1 PTPN11 4441317 4441096 9606.ENSP00000343204 9606.ENSP00000340944 0 0 0.0 0.0 0.062 0 0.9 0.766 0.976 IL6 MAPK3 4447254 4435180 9606.ENSP00000385675 9606.ENSP00000263025 0 0 0.0 0.0 0.0 0 0.9 0.771 0.976 IL6 IL6ST 4447254 4445526 9606.ENSP00000385675 9606.ENSP00000370698 0 0 0.0 0.0 0.052 0 0.9 0.774 0.976 SOCS1 IL4 4440100 4433533 9606.ENSP00000329418 9606.ENSP00000231449 0 0 0.0 0.0 0.0 0 0.9 0.773 0.976 IL6R SOCS3 4443110 4440175 9606.ENSP00000357470 9606.ENSP00000330341 0 0 0.0 0.0 0.0 0 0.9 0.774 0.976 IL6 JAK2 4447254 4445579 9606.ENSP00000385675 9606.ENSP00000371067 0 0 0.0 0.0 0.064 0 0.9 0.756 0.975 FGF2 MAPK1 4435443 4432880 9606.ENSP00000264498 9606.ENSP00000215832 0 0 0.0 0.0 0.0 0 0.9 0.752 0.974 SRC MMP2 4444215 4433061 9606.ENSP00000362680 9606.ENSP00000219070 0 0 0.0 0.0 0.055 0 0.9 0.748 0.974 HIF1A EGFR 4449842 4436186 9606.ENSP00000437955 9606.ENSP00000275493 0 0 0.0 0.0 0.0 0 0.9 0.743 0.973 MCL1 TP53 4443243 4435880 9606.ENSP00000358022 9606.ENSP00000269305 0 0 0.0 0.0 0.05 0 0.9 0.739 0.973 AKT1 PTPN11 4450372 4441096 9606.ENSP00000451828 9606.ENSP00000340944 0 0 0.0 0.0 0.088 0 0.9 0.727 0.972 IL10 IL4 4448642 4433533 9606.ENSP00000412237 9606.ENSP00000231449 0 0 0.0 0.0 0.0 0 0.0 0.972 0.972 JAK2 IL23R 4445579 4439435 9606.ENSP00000371067 9606.ENSP00000321345 0 0 0.0 0.0 0.0 0 0.9 0.741 0.972 IL10 IL10RB 4448642 4436842 9606.ENSP00000412237 9606.ENSP00000290200 0 0 0.0 0.0 0.0 0 0.9 0.732 0.972 VEGFA FGF2 4451310 4435443 9606.ENSP00000478570 9606.ENSP00000264498 0 0 0.0 0.0 0.0 0 0.0 0.97 0.971 IL10 IL17A 4448642 4441397 9606.ENSP00000412237 9606.ENSP00000344192 0 0 0.0 0.0 0.064 0 0.0 0.97 0.971 IL6 IL17A 4447254 4441397 9606.ENSP00000385675 9606.ENSP00000344192 0 0 0.0 0.0 0.061 0 0.0 0.97 0.971 IL13 IL4 4438088 4433533 9606.ENSP00000304915 9606.ENSP00000231449 0 0 0.0 0.0 0.07 0 0.0 0.97 0.971 TP53 MAPK1 4435880 4432880 9606.ENSP00000269305 9606.ENSP00000215832 0 0 0.0 0.0 0.055 0 0.8 0.859 0.971 JAK1 SOCS3 4441317 4440175 9606.ENSP00000343204 9606.ENSP00000330341 0 0 0.0 0.0 0.082 0 0.9 0.709 0.97 FOS CCL2 4438204 4433339 9606.ENSP00000306245 9606.ENSP00000225831 0 0 0.0 0.0 0.0 0 0.9 0.719 0.97 JAK1 IL13 4441317 4438088 9606.ENSP00000343204 9606.ENSP00000304915 0 0 0.0 0.0 0.0 0 0.9 0.714 0.97 FGF2 MAPK3 4435443 4435180 9606.ENSP00000264498 9606.ENSP00000263025 0 0 0.0 0.0 0.0 0 0.9 0.715 0.97 BCL2L1 MAPK3 4437866 4435180 9606.ENSP00000302564 9606.ENSP00000263025 0 0 0.0 0.0 0.059 0 0.9 0.7 0.969 TYK2 IL4 4449608 4433533 9606.ENSP00000431885 9606.ENSP00000231449 0 0 0.0 0.0 0.0 0 0.9 0.707 0.969 MYC MAPK3 4451407 4435180 9606.ENSP00000479618 9606.ENSP00000263025 0 0 0.0 0.0 0.0 0 0.9 0.707 0.969 FOS TP53 4438204 4435880 9606.ENSP00000306245 9606.ENSP00000269305 0 0 0.0 0.0 0.0 0 0.9 0.706 0.969 PTPN11 CSF2 4441096 4437349 9606.ENSP00000340944 9606.ENSP00000296871 0 0 0.0 0.0 0.0 0 0.9 0.706 0.969 AKT1 RAC1 4450372 4441834 9606.ENSP00000451828 9606.ENSP00000348461 0 0 0.0 0.0 0.063 0 0.9 0.687 0.968 IL6 JAK1 4447254 4441317 9606.ENSP00000385675 9606.ENSP00000343204 0 0 0.0 0.0 0.061 0 0.9 0.696 0.968 JAK1 SOCS1 4441317 4440100 9606.ENSP00000343204 9606.ENSP00000329418 0 0 0.0 0.0 0.049 0 0.9 0.698 0.968 FOS CCND1 4438204 4433391 9606.ENSP00000306245 9606.ENSP00000227507 0 0 0.0 0.0 0.0 0 0.9 0.685 0.967 HIF1A TP53 4449842 4435880 9606.ENSP00000437955 9606.ENSP00000269305 0 0 0.0 0.0 0.0 0 0.9 0.674 0.966 MYC TP53 4451407 4435880 9606.ENSP00000479618 9606.ENSP00000269305 0 0 0.0 0.0 0.091 0 0.0 0.964 0.966 MTOR EGF 4442490 4435570 9606.ENSP00000354558 9606.ENSP00000265171 0 0 0.0 0.0 0.0 0 0.9 0.668 0.965 TYK2 SOCS1 4449608 4440100 9606.ENSP00000431885 9606.ENSP00000329418 0 0 0.0 0.0 0.056 0 0.9 0.663 0.965 IL22 IL10RB 4450035 4436842 9606.ENSP00000442424 9606.ENSP00000290200 0 0 0.0 0.0 0.0 0 0.9 0.67 0.965 TYK2 SOCS3 4449608 4440175 9606.ENSP00000431885 9606.ENSP00000330341 0 0 0.0 0.0 0.061 0 0.9 0.658 0.965 JAK3 IL4 4447709 4433533 9606.ENSP00000391676 9606.ENSP00000231449 0 0 0.0 0.0 0.0 0 0.9 0.669 0.965 JAK1 IL10RB 4441317 4436842 9606.ENSP00000343204 9606.ENSP00000290200 0 0 0.0 0.0 0.061 0 0.9 0.66 0.965 JAK1 EGF 4441317 4435570 9606.ENSP00000343204 9606.ENSP00000265171 0 0 0.0 0.0 0.0 0 0.9 0.656 0.964 MYC CCND1 4451407 4433391 9606.ENSP00000479618 9606.ENSP00000227507 0 0 0.0 0.0 0.069 0 0.0 0.963 0.964 TYK2 IL23R 4449608 4439435 9606.ENSP00000431885 9606.ENSP00000321345 0 0 0.0 0.0 0.061 0 0.9 0.641 0.963 JAK2 CSF2 4445579 4437349 9606.ENSP00000371067 9606.ENSP00000296871 0 0 0.0 0.0 0.0 0 0.9 0.641 0.962 JAK3 PTPN11 4447709 4441096 9606.ENSP00000391676 9606.ENSP00000340944 0 0 0.0 0.0 0.062 0 0.9 0.631 0.962 JAK3 SOCS1 4447709 4440100 9606.ENSP00000391676 9606.ENSP00000329418 0 0 0.0 0.0 0.062 0 0.9 0.619 0.961 TYK2 IL6 4449608 4447254 9606.ENSP00000431885 9606.ENSP00000385675 0 0 0.0 0.0 0.0 0 0.9 0.635 0.961 JAK2 CCND1 4445579 4433391 9606.ENSP00000371067 9606.ENSP00000227507 0 0 0.0 0.0 0.0 0 0.9 0.622 0.96 IL6 CSF2 4447254 4437349 9606.ENSP00000385675 9606.ENSP00000296871 0 0 0.0 0.0 0.172 0 0.0 0.952 0.959 SRC RAC1 4444215 4441834 9606.ENSP00000362680 9606.ENSP00000348461 0 0 0.0 0.0 0.0 0 0.9 0.607 0.959 JAK3 IL6 4447709 4447254 9606.ENSP00000391676 9606.ENSP00000385675 0 0 0.0 0.0 0.062 0 0.9 0.601 0.959 JAK3 SOCS3 4447709 4440175 9606.ENSP00000391676 9606.ENSP00000330341 0 0 0.0 0.0 0.062 0 0.9 0.605 0.959 VEGFA IL6 4451310 4447254 9606.ENSP00000478570 9606.ENSP00000385675 0 0 0.0 0.0 0.063 0 0.0 0.957 0.959 EGF FGF2 4435570 4435443 9606.ENSP00000265171 9606.ENSP00000264498 0 0 0.0 0.0 0.0 0 0.0 0.958 0.958 TYK2 IL10 4449608 4448642 9606.ENSP00000431885 9606.ENSP00000412237 0 0 0.0 0.0 0.0 0 0.9 0.605 0.958 IL6R JAK1 4443110 4441317 9606.ENSP00000357470 9606.ENSP00000343204 0 0 0.0 0.0 0.061 0 0.9 0.595 0.958 PTGS2 CXCL8 4442894 4438229 9606.ENSP00000356438 9606.ENSP00000306512 0 0 0.0 0.0 0.753 0 0.0 0.839 0.958 JAK2 IL6R 4445579 4443110 9606.ENSP00000371067 9606.ENSP00000357470 0 0 0.0 0.0 0.0 0 0.9 0.606 0.958 PTPN11 EGF 4441096 4435570 9606.ENSP00000340944 9606.ENSP00000265171 0 0 0.0 0.0 0.0 0 0.9 0.595 0.957 JAK2 OSM 4445579 4432875 9606.ENSP00000371067 9606.ENSP00000215781 0 0 0.0 0.0 0.067 0 0.9 0.585 0.957 IL6ST JAK1 4445526 4441317 9606.ENSP00000370698 9606.ENSP00000343204 0 0 0.0 0.0 0.09 0 0.9 0.556 0.956 JAK1 OSM 4441317 4432875 9606.ENSP00000343204 9606.ENSP00000215781 0 0 0.0 0.0 0.0 0 0.9 0.579 0.956 IL17A IL13 4441397 4438088 9606.ENSP00000344192 9606.ENSP00000304915 0 0 0.0 0.0 0.061 0 0.0 0.954 0.955 AKT1 SRC 4450372 4444215 9606.ENSP00000451828 9606.ENSP00000362680 0 0 0.391 0.562 0.097 0 0.9 0.96 0.954 IL6 PTPN11 4447254 4441096 9606.ENSP00000385675 9606.ENSP00000340944 0 0 0.0 0.0 0.0 0 0.9 0.561 0.954 IL10 IL13 4448642 4438088 9606.ENSP00000412237 9606.ENSP00000304915 0 0 0.0 0.0 0.061 0 0.0 0.953 0.954 VEGFA CXCL8 4451310 4438229 9606.ENSP00000478570 9606.ENSP00000306512 0 0 0.0 0.0 0.065 0 0.0 0.953 0.954 JAK2 IL4 4445579 4433533 9606.ENSP00000371067 9606.ENSP00000231449 0 0 0.0 0.0 0.0 0 0.9 0.559 0.954 CSF2 MAPK3 4437349 4435180 9606.ENSP00000296871 9606.ENSP00000263025 0 0 0.0 0.0 0.0 0 0.9 0.557 0.953 IL6ST OSM 4445526 4432875 9606.ENSP00000370698 9606.ENSP00000215781 0 0 0.0 0.0 0.0 0 0.9 0.55 0.953 TYK2 PTPN11 4449608 4441096 9606.ENSP00000431885 9606.ENSP00000340944 0 0 0.0 0.0 0.062 0 0.9 0.529 0.952 CSF2 MAPK1 4437349 4432880 9606.ENSP00000296871 9606.ENSP00000215832 0 0 0.0 0.0 0.0 0 0.9 0.542 0.952 EGFR TP53 4436186 4435880 9606.ENSP00000275493 9606.ENSP00000269305 0 0 0.0 0.0 0.0 0 0.0 0.951 0.951 IL17A IL4 4441397 4433533 9606.ENSP00000344192 9606.ENSP00000231449 0 0 0.0 0.0 0.0 0 0.0 0.95 0.951 VEGFA AKT1 4451310 4450372 9606.ENSP00000478570 9606.ENSP00000451828 0 0 0.0 0.0 0.063 0 0.0 0.95 0.951 TYK2 IL6R 4449608 4443110 9606.ENSP00000431885 9606.ENSP00000357470 0 0 0.0 0.0 0.061 0 0.9 0.52 0.95 JAK1 CSF2 4441317 4437349 9606.ENSP00000343204 9606.ENSP00000296871 0 0 0.0 0.0 0.0 0 0.9 0.526 0.95 POMC LEP 4447072 4438805 9606.ENSP00000384092 9606.ENSP00000312652 0 0 0.0 0.0 0.0 0 0.0 0.949 0.949 TYK2 OSM 4449608 4432875 9606.ENSP00000431885 9606.ENSP00000215781 0 0 0.0 0.0 0.0 0 0.9 0.51 0.948 IL22 TYK2 4450035 4449608 9606.ENSP00000442424 9606.ENSP00000431885 0 0 0.0 0.0 0.0 0 0.9 0.51 0.948 JAK2 IL13 4445579 4438088 9606.ENSP00000371067 9606.ENSP00000304915 0 0 0.0 0.0 0.0 0 0.9 0.492 0.947 TP53 MAPK3 4435880 4435180 9606.ENSP00000269305 9606.ENSP00000263025 0 0 0.0 0.0 0.062 0 0.8 0.737 0.946 RAC1 MAPK3 4441834 4435180 9606.ENSP00000348461 9606.ENSP00000263025 0 0 0.0 0.0 0.061 0 0.9 0.47 0.945 PTPN11 LEP 4441096 4438805 9606.ENSP00000340944 9606.ENSP00000312652 0 0 0.0 0.0 0.0 0 0.9 0.475 0.945 IL6 PTGS2 4447254 4442894 9606.ENSP00000385675 9606.ENSP00000356438 0 0 0.0 0.0 0.314 0 0.0 0.922 0.945 TYK2 IL13 4449608 4438088 9606.ENSP00000431885 9606.ENSP00000304915 0 0 0.0 0.0 0.0 0 0.9 0.478 0.945 IL6ST PTPN11 4445526 4441096 9606.ENSP00000370698 9606.ENSP00000340944 0 0 0.0 0.0 0.061 0 0.9 0.469 0.945 HIF1A MAPK3 4449842 4435180 9606.ENSP00000437955 9606.ENSP00000263025 0 0 0.0 0.0 0.0 0 0.8 0.737 0.945 JAK3 CSF2 4447709 4437349 9606.ENSP00000391676 9606.ENSP00000296871 0 0 0.0 0.0 0.0 0 0.9 0.479 0.945 VEGFA PTPN11 4451310 4441096 9606.ENSP00000478570 9606.ENSP00000340944 0 0 0.0 0.0 0.0 0 0.9 0.472 0.944 JAK3 IL6R 4447709 4443110 9606.ENSP00000391676 9606.ENSP00000357470 0 0 0.0 0.0 0.069 0 0.9 0.454 0.944 IL22 JAK1 4450035 4441317 9606.ENSP00000442424 9606.ENSP00000343204 0 0 0.0 0.0 0.0 0 0.9 0.47 0.944 JAK2 IL6ST 4445579 4445526 9606.ENSP00000371067 9606.ENSP00000370698 0 0 0.0 0.0 0.062 0 0.9 0.458 0.944 MYC SOX2 4451407 4439616 9606.ENSP00000479618 9606.ENSP00000323588 0 0 0.0 0.0 0.0 0 0.0 0.943 0.943 SRC PTPN11 4444215 4441096 9606.ENSP00000362680 9606.ENSP00000340944 0 0 0.0 0.55 0.063 0 0.9 0.93 0.943 AKT1 CCND1 4450372 4433391 9606.ENSP00000451828 9606.ENSP00000227507 0 0 0.0 0.0 0.061 0 0.0 0.941 0.943 TP53 CCND1 4435880 4433391 9606.ENSP00000269305 9606.ENSP00000227507 0 0 0.0 0.0 0.061 0 0.0 0.942 0.943 CXCL8 CCL2 4438229 4433339 9606.ENSP00000306512 9606.ENSP00000225831 0 0 0.0 0.0 0.278 0 0.0 0.925 0.943 IL6 LEP 4447254 4438805 9606.ENSP00000385675 9606.ENSP00000312652 0 0 0.0 0.0 0.0 0 0.0 0.942 0.943 IL6ST SOCS3 4445526 4440175 9606.ENSP00000370698 9606.ENSP00000330341 0 0 0.0 0.0 0.065 0 0.9 0.433 0.942 RAC1 EGF 4441834 4435570 9606.ENSP00000348461 9606.ENSP00000265171 0 0 0.0 0.0 0.0 0 0.9 0.434 0.941 SRC MAPK3 4444215 4435180 9606.ENSP00000362680 9606.ENSP00000263025 0 0 0.308 0.611 0.061 0 0.9 0.867 0.941 RAC1 EGFR 4441834 4436186 9606.ENSP00000348461 9606.ENSP00000275493 0 0 0.0 0.0 0.0 0 0.9 0.44 0.941 JAK3 IL21 4447709 4435442 9606.ENSP00000391676 9606.ENSP00000264497 0 0 0.0 0.0 0.0 0 0.9 0.432 0.94 SRC MAPK1 4444215 4432880 9606.ENSP00000362680 9606.ENSP00000215832 0 0 0.311 0.626 0.061 0 0.9 0.871 0.94 RAC1 MAPK1 4441834 4432880 9606.ENSP00000348461 9606.ENSP00000215832 0 0 0.0 0.0 0.061 0 0.9 0.42 0.94 POMC CXCL8 4447072 4438229 9606.ENSP00000384092 9606.ENSP00000306512 0 0 0.0 0.0 0.0 0 0.9 0.422 0.939 IL6R PTPN11 4443110 4441096 9606.ENSP00000357470 9606.ENSP00000340944 0 0 0.0 0.0 0.0 0 0.9 0.422 0.939 IL6R MAPK3 4443110 4435180 9606.ENSP00000357470 9606.ENSP00000263025 0 0 0.0 0.0 0.0 0 0.9 0.42 0.939 JAK2 FGF2 4445579 4435443 9606.ENSP00000371067 9606.ENSP00000264498 0 0 0.0 0.0 0.0 0 0.9 0.416 0.939 PTPN11 FGF2 4441096 4435443 9606.ENSP00000340944 9606.ENSP00000264498 0 0 0.0 0.0 0.0 0 0.9 0.41 0.938 TYK2 IL6ST 4449608 4445526 9606.ENSP00000431885 9606.ENSP00000370698 0 0 0.0 0.0 0.0 0 0.9 0.413 0.938 IL6ST IL6R 4445526 4443110 9606.ENSP00000370698 9606.ENSP00000357470 0 0 0.0 0.559 0.062 0 0.9 0.827 0.937 EGFR MAPK3 4436186 4435180 9606.ENSP00000275493 9606.ENSP00000263025 0 0 0.0 0.58 0.0 0 0.9 0.886 0.937 EGFR MAPK1 4436186 4432880 9606.ENSP00000275493 9606.ENSP00000215832 0 0 0.0 0.577 0.0 0 0.9 0.887 0.937 SOCS3 IL23R 4440175 4439435 9606.ENSP00000330341 9606.ENSP00000321345 0 0 0.0 0.0 0.0 0 0.9 0.369 0.934 MCL1 BCL2L1 4443243 4437866 9606.ENSP00000358022 9606.ENSP00000302564 0 0 0.0 0.622 0.0 0 0.9 0.928 0.934 IL17A IL17F 4441397 4440787 9606.ENSP00000344192 9606.ENSP00000337432 0 0 0.0 0.901 0.298 0 0.9 0.92 0.933 JAK1 IL21 4441317 4435442 9606.ENSP00000343204 9606.ENSP00000264497 0 0 0.0 0.0 0.0 0 0.9 0.361 0.933 JAK2 SRC 4445579 4444215 9606.ENSP00000371067 9606.ENSP00000362680 0 0 0.0 0.636 0.061 0 0.9 0.851 0.932 AKT1 EGF 4450372 4435570 9606.ENSP00000451828 9606.ENSP00000265171 0 0 0.0 0.0 0.0 0 0.0 0.932 0.932 SRC FOS 4444215 4438204 9606.ENSP00000362680 9606.ENSP00000306245 0 0 0.0 0.0 0.0 0 0.8 0.676 0.932 SRC EGFR 4444215 4436186 9606.ENSP00000362680 9606.ENSP00000275493 0 0 0.0 0.671 0.0 0 0.9 0.954 0.931 JAK1 MAPK1 4441317 4432880 9606.ENSP00000343204 9606.ENSP00000215832 0 0 0.0 0.608 0.176 0 0.9 0.539 0.931 EGFR FGF2 4436186 4435443 9606.ENSP00000275493 9606.ENSP00000264498 0 0 0.0 0.0 0.098 0 0.6 0.824 0.931 SOCS3 SOCS1 4440175 4440100 9606.ENSP00000330341 9606.ENSP00000329418 0 0 0.0 0.739 0.129 0 0.9 0.889 0.93 IL17A CCL2 4441397 4433339 9606.ENSP00000344192 9606.ENSP00000225831 0 0 0.0 0.0 0.0 0 0.0 0.93 0.93 IL6R MAPK1 4443110 4432880 9606.ENSP00000357470 9606.ENSP00000215832 0 0 0.0 0.0 0.0 0 0.9 0.324 0.929 JAK2 MAPK3 4445579 4435180 9606.ENSP00000371067 9606.ENSP00000263025 0 0 0.0 0.603 0.064 0 0.9 0.722 0.929 AKT1 JAK1 4450372 4441317 9606.ENSP00000451828 9606.ENSP00000343204 0 0 0.0 0.571 0.062 0 0.9 0.663 0.929 JAK1 MAPK3 4441317 4435180 9606.ENSP00000343204 9606.ENSP00000263025 0 0 0.0 0.6 0.113 0 0.9 0.601 0.929 JAK2 MAPK1 4445579 4432880 9606.ENSP00000371067 9606.ENSP00000215832 0 0 0.0 0.606 0.064 0 0.9 0.644 0.926 JAK1 FGF2 4441317 4435443 9606.ENSP00000343204 9606.ENSP00000264498 0 0 0.0 0.0 0.0 0 0.9 0.295 0.926 AKT1 JAK3 4450372 4447709 9606.ENSP00000451828 9606.ENSP00000391676 0 0 0.0 0.584 0.05 0 0.9 0.599 0.924 JAK1 EGFR 4441317 4436186 9606.ENSP00000343204 9606.ENSP00000275493 0 0 0.0 0.569 0.0 0 0.9 0.597 0.924 IL6 MMP9 4447254 4443919 9606.ENSP00000385675 9606.ENSP00000361405 0 0 0.0 0.0 0.074 0 0.0 0.92 0.923 IL6 IL23R 4447254 4439435 9606.ENSP00000385675 9606.ENSP00000321345 0 0 0.0 0.0 0.0 0 0.6 0.813 0.922 CSF2 IL4 4437349 4433533 9606.ENSP00000296871 9606.ENSP00000231449 0 0 0.0 0.0 0.0 0 0.0 0.921 0.921 IL6 EGFR 4447254 4436186 9606.ENSP00000385675 9606.ENSP00000275493 0 0 0.0 0.0 0.0 0 0.6 0.811 0.921 JAK3 MAPK3 4447709 4435180 9606.ENSP00000391676 9606.ENSP00000263025 0 0 0.0 0.592 0.064 0 0.9 0.507 0.921 JAK3 MAPK1 4447709 4432880 9606.ENSP00000391676 9606.ENSP00000215832 0 0 0.0 0.597 0.064 0 0.9 0.479 0.92 VEGFA PTGS2 4451310 4442894 9606.ENSP00000478570 9606.ENSP00000356438 0 0 0.0 0.0 0.082 0 0.0 0.914 0.918 VEGFA TP53 4451310 4435880 9606.ENSP00000478570 9606.ENSP00000269305 0 0 0.0 0.0 0.0 0 0.0 0.918 0.918 TYK2 MAPK1 4449608 4432880 9606.ENSP00000431885 9606.ENSP00000215832 0 0 0.0 0.594 0.0 0 0.9 0.423 0.916 TYK2 MAPK3 4449608 4435180 9606.ENSP00000431885 9606.ENSP00000263025 0 0 0.0 0.589 0.0 0 0.9 0.432 0.916 VEGFA CCL2 4451310 4433339 9606.ENSP00000478570 9606.ENSP00000225831 0 0 0.0 0.0 0.0 0 0.0 0.914 0.914 TYK2 JAK3 4449608 4447709 9606.ENSP00000431885 9606.ENSP00000391676 0 0 0.0 0.871 0.062 0 0.9 0.867 0.913 JAK3 FGF2 4447709 4435443 9606.ENSP00000391676 9606.ENSP00000264498 0 0 0.0 0.0 0.0 0 0.9 0.174 0.913 CSF2 CCL2 4437349 4433339 9606.ENSP00000296871 9606.ENSP00000225831 0 0 0.0 0.0 0.063 0 0.0 0.91 0.913 JAK3 JAK1 4447709 4441317 9606.ENSP00000391676 9606.ENSP00000343204 0 0 0.0 0.892 0.061 0 0.9 0.949 0.912 JAK2 JAK1 4445579 4441317 9606.ENSP00000371067 9606.ENSP00000343204 0 0 0.0 0.911 0.085 0 0.9 0.963 0.912 TYK2 JAK2 4449608 4445579 9606.ENSP00000431885 9606.ENSP00000371067 0 0 0.0 0.881 0.061 0 0.9 0.932 0.912 IL22 PTPN11 4450035 4441096 9606.ENSP00000442424 9606.ENSP00000340944 0 0 0.0 0.0 0.0 0 0.9 0.137 0.91 TYK2 JAK1 4449608 4441317 9606.ENSP00000431885 9606.ENSP00000343204 0 0 0.0 0.926 0.061 0 0.9 0.952 0.908 IL6 BCL6 4447254 4447113 9606.ENSP00000385675 9606.ENSP00000384371 0 0 0.0 0.0 0.0 0 0.0 0.907 0.908 IL22 IL17F 4450035 4440787 9606.ENSP00000442424 9606.ENSP00000337432 0 0 0.0 0.0 0.194 0 0.0 0.891 0.908 MMP9 MMP2 4443919 4433061 9606.ENSP00000361405 9606.ENSP00000219070 0 0 0.0 0.929 0.061 0 0.9 0.958 0.908 CXCL8 CSF2 4438229 4437349 9606.ENSP00000306512 9606.ENSP00000296871 0 0 0.0 0.0 0.148 0 0.0 0.895 0.906 PTPN11 IL10RB 4441096 4436842 9606.ENSP00000340944 9606.ENSP00000290200 0 0 0.0 0.0 0.0 0 0.9 0.089 0.905 EGFR CCND1 4436186 4433391 9606.ENSP00000275493 9606.ENSP00000227507 0 0 0.0 0.0 0.2 0 0.0 0.886 0.905 JAK3 JAK2 4447709 4445579 9606.ENSP00000391676 9606.ENSP00000371067 0 0 0.0 0.943 0.0 0 0.9 0.872 0.904 MAPK3 MAPK1 4435180 4432880 9606.ENSP00000263025 9606.ENSP00000215832 0 0 0.446 0.983 0.0 0 0.9 0.951 0.902