Creatine kinase U-type, mitochondrial
AltitudeomicsDB
| Protein Official symbol |
CKMT1B |
| Aliases |
CKMT1A CKMT; CKMT1B CKMT |
| Chromosomal Location |
15 |
| Length |
417 |
| Uniprot ID |
P12532 |
| EC number |
2.7.3.2 |
| Protein family Information(Pfam) |
PF00217;PF02807; |
| PDB id |
1QK1; |
| InterPro ID |
IPR000749;IPR022415;IPR022414;IPR022413;IPR036802;IPR014746; |
| dbSNP |
None |
AltitudeomicsDB
| Protein 1 |
Protein 2 |
Combine Score |
| STRC |
CATSPER2 |
0.962 |
| CKMT1A |
CKMT1B |
0.952 |
| CKMT1A |
ASB9 |
0.93 |
| ASB9 |
CKMT1B |
0.849 |
| CKMT1B |
GPD1L |
0.822 |
| CKMT1A |
GPD1L |
0.822 |
| CKMT1B |
SLC6A8 |
0.813 |
| CKMT1A |
SLC6A8 |
0.812 |
| CKMT1A |
STRC |
0.809 |
| CKMT1A |
CATSPER2 |
0.809 |
| STRC |
CKMT1B |
0.808 |
| CATSPER2 |
CKMT1B |
0.808 |
Gene Ontology Semantic Similarity
Download Tab separated file
| # |
140462 (ASB9) |
1159 (CKMT1B) |
548596 (CKMT1A) |
117155 (CATSPER2) |
23171 (GPD1L) |
6535 (SLC6A8) |
2167 (FABP4) |
|
140462 (ASB9)
|
1.00
|
0.14
|
0.14
|
1.00
|
0.82
|
0.48
|
0.30
|
|
1159 (CKMT1B)
|
0.14
|
1.00
|
1.00
|
0.14
|
0.18
|
0.24
|
0.08
|
|
548596 (CKMT1A)
|
0.14
|
1.00
|
1.00
|
0.14
|
0.18
|
0.24
|
0.08
|
|
117155 (CATSPER2)
|
1.00
|
0.14
|
0.14
|
1.00
|
0.82
|
0.48
|
0.30
|
|
23171 (GPD1L)
|
0.82
|
0.18
|
0.18
|
0.82
|
1.00
|
0.24
|
0.17
|
|
6535 (SLC6A8)
|
0.48
|
0.24
|
0.24
|
0.48
|
0.24
|
1.00
|
0.22
|
|
2167 (FABP4)
|
0.30
|
0.08
|
0.08
|
0.30
|
0.17
|
0.22
|
1.00
|
Association with High Altitude
| Protein Official symbol |
Source Organism |
Tissue of Expression |
Level of hypoxia |
Altitude |
Duration of experiment |
Level of expression |
Fold change |
Experiment details |
geographical location |
ethnicity of the patients |
Control group |
Control (Fold change) |
Reference (PMID) |
| CKMT1B |
Toad |
Heart |
- |
3464 m |
33 day |
downregulated |
-2.280330265 |
RNA-seq |
Tibetan Plateau |
Asiatic toad |
1 |
Zoige (High altitute Toad) Vs Chengdu (Low altitude toad) - |
28673260 |
Association with TF
| TF |
TF Entrez |
Gene |
Gene Entrez |
Type |
PMID |
Database |
| EP300 |
2033 |
CKMT1B |
1159 |
distal |
22955619 |
TRANSFAC |
Association with miRNA
| miRTarBase ID |
miRNA |
Species (miRNA) |
Protein Official Symbol |
Human Entrez ID |
Species (Target Gene) |
Experiments |
Support Type |
References (PMID) |
| MIRT049393 |
hsa-miR-92a-3p |
Homo sapiens |
CKMT1B |
1159 |
Homo sapiens |
CLASH |
Functional MTI (Weak) |
23622248 |
Gene Ontology
| ID |
GO ID |
GO Term |
GO Type |
| 1159 |
GO:0016772 |
transferase activity |
GOTERM_MF_DIRECT |
| 1159 |
GO:0005743 |
mitochondrial inner membrane |
GOTERM_CC_DIRECT |
| 1159 |
GO:0006600 |
creatine metabolic process |
GOTERM_BP_DIRECT |
| 1159 |
GO:0016310 |
phosphorylation |
GOTERM_BP_DIRECT |
| 1159 |
GO:0004111 |
catalase activity |
GOTERM_MF_DIRECT |
| 1159 |
GO:0070062 |
extracellular exosome |
GOTERM_CC_DIRECT |
| 1159 |
GO:0016301 |
kinase activity |
GOTERM_MF_DIRECT |
| 1159 |
GO:0005524 |
ATP binding |
GOTERM_MF_DIRECT |
| 1159 |
GO:0005739 |
mitochondrion |
GOTERM_CC_DIRECT |
Pathways
| Human Entrez ID |
KEGG ID |
KEGG Term |
| 1159 |
hsa00330 |
Arginine and proline metabolism |
| 1159 |
hsa01100 |
Metabolic pathways |
Association with Disease
| Protein Official Symbol |
Human Entrez ID |
Disease Name |
Disease Id |
Disease Semantic Type |
Semantic score |
DSI |
DPI |
Disease Type |
Association with Drug
| Protein Official Symbol |
Human Entrez ID |
drug_claim_primary_name |
drug_name |
drug_chembl_id |
interaction_types |