| Protein Official symbol | ANTXR2 |
| Aliases | ANTXR2 CMG2 |
| Chromosomal Location | 4 |
| Length | 489 |
| Uniprot ID | P58335 |
| EC number | None |
| Protein family Information(Pfam) | PF05586;PF05587;PF00092; |
| PDB id | 1SHT;1SHU;1T6B;1TZN; |
| InterPro ID | IPR017360;IPR008399;IPR008400;IPR002035;IPR036465; |
| dbSNP | rs886041401 rs137852902 rs137852905 rs781637328 rs137852903 rs12647691 rs137852901 |
| Protein 1 | Protein 2 | Combine Score |
|---|---|---|
| FURIN | ANTXR2 | 0.969 |
| FURIN | ANTXR1 | 0.966 |
| ANTXR2 | ANTXR1 | 0.906 |
| # | 5045 (FURIN) | 118429 (ANTXR2) |
|---|---|---|
| 5045 (FURIN) | 1.00 | 0.45 |
| 118429 (ANTXR2) | 0.45 | 1.00 |
| Protein Official symbol | Source Organism | Tissue of Expression | Level of hypoxia | Altitude | Duration of experiment | Level of expression | Fold change | Experiment details | geographical location | ethnicity of the patients | Control group | Control (Fold change) | Reference (PMID) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ANTXR2 | Toad | Liver | - | 3464 m | 33 day | downregulated | -2.402209331 | RNA-seq | Tibetan Plateau | Asiatic toad | 1 | Zoige (High altitute Toad) Vs Chengdu (Low altitude toad) - | 28673260 |
| TF | TF Entrez | Gene | Gene Entrez | Type | PMID | Database |
|---|
| miRTarBase ID | miRNA | Species (miRNA) | Protein Official Symbol | Human Entrez ID | Species (Target Gene) | Experiments | Support Type | References (PMID) |
|---|---|---|---|---|---|---|---|---|
| MIRT017139 | hsa-miR-335-5p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | Microarray | Functional MTI (Weak) | 18185580 |
| MIRT044967 | hsa-miR-186-5p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | CLASH | Functional MTI (Weak) | 23622248 |
| MIRT390883 | hsa-miR-7110-3p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | HITS-CLIP | Functional MTI (Weak) | 23824327 |
| MIRT390881 | hsa-miR-6817-3p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | HITS-CLIP | Functional MTI (Weak) | 23824327 |
| MIRT449366 | hsa-miR-3136-5p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | PAR-CLIP | Functional MTI (Weak) | 22100165 |
| MIRT449373 | hsa-miR-7161-3p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | PAR-CLIP | Functional MTI (Weak) | 22100165 |
| MIRT449376 | hsa-miR-5190 | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | PAR-CLIP | Functional MTI (Weak) | 22100165 |
| MIRT449365 | hsa-miR-4439 | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | PAR-CLIP | Functional MTI (Weak) | 22100165 |
| MIRT449367 | hsa-miR-466 | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | PAR-CLIP | Functional MTI (Weak) | 22100165 |
| MIRT449371 | hsa-miR-6855-3p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | PAR-CLIP | Functional MTI (Weak) | 22100165 |
| MIRT449370 | hsa-miR-3941 | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | PAR-CLIP | Functional MTI (Weak) | 22100165 |
| MIRT449377 | hsa-miR-548p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | PAR-CLIP | Functional MTI (Weak) | 22100165 |
| MIRT449374 | hsa-miR-888-3p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | PAR-CLIP | Functional MTI (Weak) | 22100165 |
| MIRT449364 | hsa-miR-943 | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | PAR-CLIP | Functional MTI (Weak) | 22100165 |
| MIRT449375 | hsa-miR-6768-5p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | PAR-CLIP | Functional MTI (Weak) | 22100165 |
| MIRT449369 | hsa-miR-6857-3p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | PAR-CLIP | Functional MTI (Weak) | 22100165 |
| MIRT449378 | hsa-miR-5692a | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | PAR-CLIP | Functional MTI (Weak) | 22100165 |
| MIRT449368 | hsa-miR-4672 | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | PAR-CLIP | Functional MTI (Weak) | 22100165 |
| MIRT449372 | hsa-miR-4513 | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | PAR-CLIP | Functional MTI (Weak) | 22100165 |
| MIRT539207 | hsa-miR-1288-5p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | PAR-CLIP | Functional MTI (Weak) | 22012620 |
| MIRT539210 | hsa-miR-3529-3p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | PAR-CLIP | Functional MTI (Weak) | 22012620 |
| MIRT539199 | hsa-miR-6788-5p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | PAR-CLIP | Functional MTI (Weak) | 22012620 |
| MIRT539204 | hsa-miR-8085 | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | PAR-CLIP | Functional MTI (Weak) | 22012620 |
| MIRT539200 | hsa-miR-30c-2-3p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | PAR-CLIP | Functional MTI (Weak) | 22012620 |
| MIRT539205 | hsa-miR-6731-5p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | PAR-CLIP | Functional MTI (Weak) | 22012620 |
| MIRT539206 | hsa-miR-6878-5p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | PAR-CLIP | Functional MTI (Weak) | 22012620 |
| MIRT539201 | hsa-miR-30c-1-3p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | PAR-CLIP | Functional MTI (Weak) | 22012620 |
| MIRT539210 | hsa-miR-3529-3p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | HITS-CLIP | Functional MTI (Weak) | 23824327 |
| MIRT539202 | hsa-miR-6778-5p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | PAR-CLIP | Functional MTI (Weak) | 22012620 |
| MIRT539203 | hsa-miR-1233-5p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | PAR-CLIP | Functional MTI (Weak) | 22012620 |
| MIRT539208 | hsa-miR-4678 | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | PAR-CLIP | Functional MTI (Weak) | 22012620 |
| MIRT539209 | hsa-miR-5694 | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | PAR-CLIP | Functional MTI (Weak) | 22012620 |
| MIRT613327 | hsa-miR-342-3p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | HITS-CLIP | Functional MTI (Weak) | 23824327 |
| MIRT613326 | hsa-miR-4724-3p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | HITS-CLIP | Functional MTI (Weak) | 23824327 |
| MIRT613328 | hsa-miR-8485 | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | HITS-CLIP | Functional MTI (Weak) | 23824327 |
| MIRT613325 | hsa-miR-377-3p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | HITS-CLIP | Functional MTI (Weak) | 23824327 |
| MIRT624733 | hsa-miR-889-3p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | HITS-CLIP | Functional MTI (Weak) | 23824327 |
| MIRT624734 | hsa-miR-1277-5p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | HITS-CLIP | Functional MTI (Weak) | 23824327 |
| MIRT628436 | hsa-miR-937-5p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | HITS-CLIP | Functional MTI (Weak) | 23824327 |
| MIRT628441 | hsa-miR-5702 | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | HITS-CLIP | Functional MTI (Weak) | 23824327 |
| MIRT628435 | hsa-miR-629-3p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | HITS-CLIP | Functional MTI (Weak) | 23824327 |
| MIRT628440 | hsa-miR-642a-5p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | HITS-CLIP | Functional MTI (Weak) | 23824327 |
| MIRT628437 | hsa-miR-6873-3p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | HITS-CLIP | Functional MTI (Weak) | 23824327 |
| MIRT628447 | hsa-miR-6892-3p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | HITS-CLIP | Functional MTI (Weak) | 23824327 |
| MIRT628438 | hsa-miR-6867-3p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | HITS-CLIP | Functional MTI (Weak) | 23824327 |
| MIRT628444 | hsa-miR-7113-3p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | HITS-CLIP | Functional MTI (Weak) | 23824327 |
| MIRT628432 | hsa-miR-6809-3p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | HITS-CLIP | Functional MTI (Weak) | 23824327 |
| MIRT628448 | hsa-miR-5571-5p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | HITS-CLIP | Functional MTI (Weak) | 23824327 |
| MIRT628434 | hsa-miR-4768-5p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | HITS-CLIP | Functional MTI (Weak) | 23824327 |
| MIRT628439 | hsa-miR-4713-5p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | HITS-CLIP | Functional MTI (Weak) | 23824327 |
| MIRT628442 | hsa-miR-4685-3p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | HITS-CLIP | Functional MTI (Weak) | 23824327 |
| MIRT628443 | hsa-miR-4287 | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | HITS-CLIP | Functional MTI (Weak) | 23824327 |
| MIRT628445 | hsa-miR-4469 | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | HITS-CLIP | Functional MTI (Weak) | 23824327 |
| MIRT628433 | hsa-miR-6833-3p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | HITS-CLIP | Functional MTI (Weak) | 23824327 |
| MIRT628446 | hsa-miR-2276-5p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | HITS-CLIP | Functional MTI (Weak) | 23824327 |
| MIRT638987 | hsa-miR-8081 | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | HITS-CLIP | Functional MTI (Weak) | 23824327 |
| MIRT638988 | hsa-miR-627-5p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | HITS-CLIP | Functional MTI (Weak) | 23824327 |
| MIRT660607 | hsa-miR-6830-3p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | HITS-CLIP | Functional MTI (Weak) | 23824327 |
| MIRT660609 | hsa-miR-3613-3p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | HITS-CLIP | Functional MTI (Weak) | 23824327 |
| MIRT660610 | hsa-miR-1264 | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | HITS-CLIP | Functional MTI (Weak) | 23824327 |
| MIRT660608 | hsa-miR-3065-5p | Homo sapiens | ANTXR2 | 118429 | Homo sapiens | HITS-CLIP | Functional MTI (Weak) | 23824327 |
| ID | GO ID | GO Term | GO Type |
|---|---|---|---|
| 118429 | GO:0005515 | protein binding | GOTERM_MF_DIRECT |
| 118429 | GO:1901998 | toxin transport | GOTERM_BP_DIRECT |
| 118429 | GO:0005576 | extracellular region | GOTERM_CC_DIRECT |
| 118429 | GO:0022414 | reproductive process | GOTERM_BP_DIRECT |
| 118429 | GO:0004872 | signal transducer activity | GOTERM_MF_DIRECT |
| 118429 | GO:0009897 | external side of plasma membrane | GOTERM_CC_DIRECT |
| 118429 | GO:0005789 | endoplasmic reticulum membrane | GOTERM_CC_DIRECT |
| 118429 | GO:0010008 | endosome membrane | GOTERM_CC_DIRECT |
| 118429 | GO:0046872 | metal ion binding | GOTERM_MF_DIRECT |
| 118429 | GO:0016021 | integral component of membrane | GOTERM_CC_DIRECT |
| 118429 | GO:0005886 | plasma membrane | GOTERM_CC_DIRECT |
| Human Entrez ID | KEGG ID | KEGG Term |
|---|
| Protein Official Symbol | Human Entrez ID | Disease Name | Disease Id | Disease Semantic Type | Semantic score | DSI | DPI | Disease Type |
|---|---|---|---|---|---|---|---|---|
| ANTXR2 | 118429 | Gingival Hypertrophy | C0017567 | Disease or Syndrome | 0.4 | 0.609 | 0.621 | disease |
| ANTXR2 | 118429 | Myxofibroma | C0205766 | Neoplastic Process | 0.3 | 0.609 | 0.621 | disease |
| ANTXR2 | 118429 | Osteoporosis, Age-Related | C0001787 | Disease or Syndrome | 0.3 | 0.609 | 0.621 | disease |
| ANTXR2 | 118429 | Osteoporosis, Senile | C0029459 | Disease or Syndrome | 0.3 | 0.609 | 0.621 | disease |
| ANTXR2 | 118429 | Contracture | C0009917 | Anatomical Abnormality | 0.3 | 0.609 | 0.621 | group |
| ANTXR2 | 118429 | Malignant neoplasm of prostate | C0376358 | Neoplastic Process | 0.3 | 0.609 | 0.621 | disease |
| ANTXR2 | 118429 | Fibromatosis | C0016048 | Neoplastic Process | 0.3 | 0.609 | 0.621 | disease |
| ANTXR2 | 118429 | Post-Traumatic Osteoporosis | C0751406 | Disease or Syndrome | 0.3 | 0.609 | 0.621 | disease |
| ANTXR2 | 118429 | fibroma | C0016045 | Neoplastic Process | 0.3 | 0.609 | 0.621 | disease |
| ANTXR2 | 118429 | Prostatic Neoplasms | C0033578 | Neoplastic Process | 0.3 | 0.609 | 0.621 | group |
| ANTXR2 | 118429 | Lytic lesion | C0221204 | Pathologic Function | 0.4 | 0.609 | 0.621 | phenotype |
| ANTXR2 | 118429 | Ankylosing spondylitis | C0038013 | Disease or Syndrome | 0.49 | 0.609 | 0.621 | disease |
| ANTXR2 | 118429 | Osteoporosis | C0029456 | Disease or Syndrome | 0.4 | 0.609 | 0.621 | disease |
| ANTXR2 | 118429 | Hyalinosis, Systemic | C2745948 | Disease or Syndrome | 0.8 | 0.609 | 0.621 | disease |
| ANTXR2 | 118429 | Arthrogryposis | C0003886 | Disease or Syndrome | 0.3 | 0.609 | 0.621 | disease |
| Protein Official Symbol | Human Entrez ID | drug_claim_primary_name | drug_name | drug_chembl_id | interaction_types |
|---|