ALTITUDEOMICSDB

Adenosine receptor A2b

AltitudeomicsDB

Protein Official symbol	ADORA2B
Aliases	ADORA2B
Chromosomal Location	17
Length	332
Uniprot ID	P29275
EC number	None
Protein family Information(Pfam)	PF00001;
PDB id	None
InterPro ID	IPR001435;IPR001634;IPR000276;IPR017452;
dbSNP	None

Protein Protein Interaction

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AltitudeomicsDB

Protein 1	Protein 2	Combine Score
POMC	CRH	0.997
CALCRL	RAMP1	0.997
CRHR1	CRH	0.997
GCG	GLP1R	0.995
ADM	CALCRL	0.995
CRHR2	CRH	0.995
VIP	VIPR2	0.995
GCG	GCGR	0.993
ADCYAP1	VIPR1	0.992
CALCA	PTH	0.992
NPS	CALCA	0.991
AVP	CRH	0.99
VIP	VIPR1	0.99
ADCYAP1	VIPR2	0.989
GCG	SCT	0.989
VIP	SCT	0.989
NPS	VIP	0.988
POMC	NPS	0.988
SCT	SCTR	0.988
ADM	CALCA	0.987
CALCRL	CALCA	0.987
VIP	CALCA	0.987
POMC	CRHR1	0.987
CALCR	CALCA	0.987
POMC	AVP	0.986
CALCA	RAMP1	0.986
NPS	CRH	0.985
ADM	RAMP1	0.985
CALCR	RAMP1	0.984
ADCYAP1	SCT	0.983
NPS	NPSR1	0.982
VIPR1	SCT	0.979
GCG	POMC	0.978
ADCYAP1	CRH	0.978
ADCYAP1	NPS	0.976
VIPR2	SCT	0.973
GCG	CALCA	0.972
ADCYAP1	GCG	0.971
GIPR	ADCY5	0.97
POMC	CALCA	0.97
POMC	CRHR2	0.97
VIP	CRH	0.969
NPS	AVP	0.969
GNAS	PTH	0.968
ADCYAP1	CALCA	0.967
GIPR	GCG	0.966
CALCA	CRH	0.966
NPS	SCT	0.966
CALCA	SCT	0.966
NPS	VIPR2	0.966
GCG	PTH	0.966
POMC	VIP	0.966
NPS	CRHR2	0.965
GCG	NPS	0.965
CRHR1	NPS	0.965
ADM	CALCR	0.965
DRD5	ADCY9	0.964
HTR7	CALCA	0.964
DRD1	ADCY9	0.964
GCGR	SCT	0.964
NPS	VIPR1	0.964
POMC	PTH	0.964
POMC	HTR7	0.964
PTH	SCT	0.963
ADM	AVP	0.963
ADCY5	DRD1	0.963
GCG	VIPR2	0.963
GCG	VIPR1	0.963
GNAS	ADCY9	0.962
NPS	HTR7	0.962
AVP	VIP	0.961
GNAS	GNG2	0.961
GNAS	ADCY1	0.961
ADCY7	DRD1	0.959
GNAS	GNB3	0.959
ADCY2	DRD5	0.959
GCG	CRH	0.959
ADCY7	DRD5	0.958
ADRB2	PTH	0.958
DRD1	ADCY2	0.958
VIP	HTR7	0.957
ADCY4	DRD5	0.957
CALCR	PTH	0.957
HTR7	CRH	0.957
CRH	SCT	0.956
PTH	SCTR	0.956
CRHR1	DRD1	0.956
POMC	ADRB3	0.956
DRD1	ADCY1	0.956
AVP	CALCA	0.956
CRHR1	NPSR1	0.956
VIP	SCTR	0.956
AVP	PTH	0.956
DRD1	ADCY4	0.956
ADRB3	GNB3	0.955
ADCY5	DRD5	0.955
ADRB2	GNB3	0.955
POMC	ADRB2	0.955
NPS	DRD1	0.955
POMC	ADRB1	0.955
ADM	VIP	0.955
GCG	AVP	0.954
GCG	SCTR	0.954
ADRB2	ADCY9	0.954
VIP	PTH	0.954
TSHR	GNAS	0.954
GLP1R	SCT	0.954
POMC	DRD1	0.953
DRD1	ADCY8	0.953
NPS	DRD5	0.953
NPSR1	CALCA	0.953
CALCA	SCTR	0.953
P2RY11	ADORA2B	0.953
CALCR	SCT	0.952
ADCYAP1	SCTR	0.952
DRD1	CRH	0.952
CRHR1	AVP	0.952
DRD5	ADCY1	0.952
POMC	DRD5	0.951
NPSR1	CRH	0.951
GNAS	ADCY2	0.951
NPSR1	PTH	0.951
ADRB1	GNB3	0.951
DRD5	ADCY8	0.951
NPSR1	VIP	0.951
CALCRL	SCT	0.95
CALCA	VIPR1	0.95
ADCYAP1	POMC	0.95
POMC	SCT	0.949
ADRB2	CRH	0.949
GIPR	SCT	0.949
POMC	GLP1R	0.949
ADRB3	CALCA	0.949
CRHR1	SCT	0.949
ADRB3	CRH	0.949
ADRB1	CRH	0.949
GCG	ADRB3	0.949
ADRB1	CALCA	0.948
CALCRL	PTH	0.948
ADM	NPS	0.948
CALCA	ADRB2	0.947
ADCYAP1	CRHR1	0.947
CRHR1	DRD5	0.947
DRD1	ADCY6	0.947
GNAS	ADCY8	0.947
CRHR1	VIP	0.947
VIPR1	RAMP1	0.947
ADCY6	DRD5	0.947
DRD5	CRH	0.946
GLP1R	CALCA	0.946
DRD1	ADCY3	0.946
ADRB1	VIP	0.946
DRD5	ADCY3	0.946
GLP1R	VIP	0.946
GCG	ADCY4	0.945
VIP	ADRB2	0.945
NPS	ADRB3	0.945
GNG2	GNB3	0.945
AVP	ADRB3	0.945
GCG	HTR7	0.945
GCG	ADCY7	0.945
GCG	ADRB2	0.945
VIP	ADRB3	0.945
POMC	GNAS	0.945
AVP	ADRB1	0.945
NPS	ADRB2	0.945
GCG	ADRB1	0.945
ADCY7	GNAS	0.944
ADM	VIPR1	0.944
ADM	POMC	0.944
NPS	ADRB1	0.944
AVP	ADRB2	0.943
CALCA	VIPR2	0.943
GCG	ADCY1	0.943
ADCY5	ADRB1	0.943
GCG	ADCY9	0.942
GCG	ADCY8	0.942
GCGR	VIP	0.942
CRHR1	ADRB2	0.942
GIPR	POMC	0.942
ADCY5	GNAS	0.942
GNAS	ADCY4	0.942
CALCRL	NPS	0.942
GCG	ADCY2	0.941
GCG	ADCY6	0.941
DRD1	VIP	0.941
ADORA2B	ADCY9	0.941
ADCY5	GCG	0.941
CRHR1	HTR7	0.941
AVP	HTR7	0.94
GCG	ADCY3	0.94
NPS	RAMP1	0.94
GCGR	RAMP1	0.94
ADCYAP1	NPSR1	0.94
PTH	CRH	0.94
ADCY7	ADORA2B	0.94
CALCRL	VIP	0.939
GCG	CRHR1	0.939
GCGR	CRH	0.939
GNAS	ADCY3	0.939
CRHR1	CALCA	0.939
RAMP1	SCT	0.939
GNAS	ADRB2	0.939
GCGR	PTH	0.939
ADCY6	ADRB2	0.939
NPSR1	VIPR2	0.939
NPS	GLP1R	0.939
DRD1	CRHR2	0.938
VIPR2	RAMP1	0.938
GIPR	ADCY8	0.938
CRH	SCTR	0.938
ADCY2	ADORA2B	0.938
AVP	CRHR2	0.938
CRHR2	SCT	0.938
ADCY5	ADRB2	0.938
ADCYAP1	GCGR	0.938
POMC	ADCY3	0.937
GIPR	LHCGR	0.937
GCGR	CALCA	0.937
NPSR1	VIPR1	0.937
GCG	CALCR	0.937
ADRB1	ADCY6	0.937
NPSR1	CRHR2	0.937
TSHR	PTH	0.937
GNAS	ADCY6	0.937
CALCRL	ADCY7	0.937
GNG2	ADCY1	0.937
ADM	GCG	0.937
ADCYAP1	GLP1R	0.937
GLP1R	PTH	0.937
CRHR2	DRD5	0.936
GIPR	ADRB1	0.936
TSHR	CALCA	0.936
POMC	ADCY8	0.936
NPSR1	PTGDR	0.936
GNAS	LHCGR	0.936
VIPR1	CRH	0.936
ADCYAP1	CALCRL	0.936
CRH	VIPR2	0.936
HTR7	SCT	0.935
ADM	VIPR2	0.935
ADCY4	ADORA2B	0.935
ADORA2B	ADCY8	0.935
VIP	DRD5	0.935
ADCYAP1	GNB3	0.935
CRHR2	HTR7	0.935
ADCY8	SCT	0.935
ADORA2B	ADCY1	0.934
ADCYAP1	ADCY8	0.934
ADCY5	ADORA2B	0.934
GLP1R	CRH	0.934
ADCYAP1	PTH	0.934
RAMP1	SCTR	0.934
CRHR1	ADRB1	0.933
ADCYAP1	ADCY1	0.933
TSHR	ADRB2	0.933
GCGR	ADCY7	0.933
NPS	SCTR	0.933
ADRB1	ADCY8	0.933
GCGR	ADCY4	0.933
CALCA	PTGIR	0.933
PTGER4	CRH	0.932
CRH	PTGER2	0.932
PTGER4	PTH	0.932
CALCRL	ADCY8	0.932
VIP	CALCR	0.932
POMC	GCGR	0.932
ADCY6	ADORA2B	0.932
ADCYAP1	ADM	0.932
ADCYAP1	RAMP1	0.932
ADCYAP1	CRHR2	0.932
GIPR	ADCY3	0.932
ADCY9	SCT	0.932
AVP	SCT	0.932
POMC	NPSR1	0.932
NPSR1	SCT	0.932
GNG2	PTGER2	0.931
VIPR1	PTH	0.931
NPS	ADORA2B	0.931
HTR7	PTGIR	0.931
ADRB2	SCT	0.931
GNAS	ADRB3	0.931
PTH	VIPR2	0.931
AVP	VIPR2	0.931
NPSR1	AVP	0.93
CRHR2	ADRB2	0.93
GCGR	ADCY1	0.93
ADCY4	SCT	0.93
VIP	ADCY1	0.93
ADRB2	PTGER2	0.93
ADCY7	SCT	0.93
CALCRL	NPSR1	0.93
CRHR1	PTH	0.93
ADCY6	PTH	0.93
ADRB1	LHCGR	0.929
ADCY6	SCT	0.929
GNAS	SCT	0.929
ADCYAP1	VIP	0.929
NPS	CALCR	0.929
GCG	CALCRL	0.929
ADCYAP1	CALCR	0.929
GCGR	ADCY9	0.929
VIP	CRHR2	0.929
VIP	PTGIR	0.929
ADRB2	LHCGR	0.929
POMC	LHCGR	0.928
ADRB2	ADCY1	0.928
ADCY5	ADCY9	0.928
ADCY5	CRHR1	0.928
ADRB3	PTH	0.928
VIP	ADORA2B	0.928
CRHR1	ADCY8	0.928
ADRB1	CRHR2	0.928
ADRB1	ADCY9	0.928
ADCYAP1	AVP	0.928
GCGR	ADCY2	0.928
ADCYAP1	DRD1	0.928
VIP	RAMP1	0.927
ADCY7	ADRB2	0.927
ADM	CRH	0.927
ADM	PTH	0.927
ADRB1	SCT	0.927
ADCY9	ADCY8	0.927
CRHR1	ADRB3	0.927
ADRB2	ADCY3	0.927
ADCY7	ADCY9	0.927
HTR7	LHCGR	0.927
GNAS	ADRB1	0.927
GCG	VIP	0.927
ADCY6	ADCY9	0.927
PTGER4	PTGER2	0.927
CALCR	CRH	0.927
GIPR	VIP	0.926
ADRB1	ADCY2	0.926
CALCA	PTGER4	0.926
ADRB3	ADCY6	0.926
GIPR	PTH	0.926
ADM	SCT	0.926
GCG	CRHR2	0.926
ADORA2B	ADCY3	0.926
CALCRL	CRH	0.926
ADCY5	PTGIR	0.926
ADRB3	SCT	0.926
NPS	PTH	0.926
NPSR1	SCTR	0.926
CALCRL	ADRB2	0.926
ADCY9	ADCY3	0.926
CRHR2	CALCA	0.926
ADRB1	PTH	0.925
ADRB2	ADCY8	0.925
ADCY7	ADRB1	0.925
GNAS	HTR7	0.925
ADCY4	PTGDR	0.925
VIP	ADCY8	0.925
GPR84	GCG	0.925
ADRB1	ADCY4	0.925
ADCY2	ADRB2	0.925
TSHR	SCTR	0.924
ADCY4	ADCY9	0.924
PTH	RAMP1	0.924
DRD1	AVP	0.924
CRHR2	ADCY9	0.924
TSHR	ADCY1	0.924
GIPR	CALCA	0.924
VIP	ADCY2	0.924
GCG	RAMP1	0.924
ADCY8	SCTR	0.924
CRHR1	RAMP1	0.924
GNAS	ADORA2B	0.924
ADCY5	ADRB3	0.924
GCGR	ADRB2	0.923
TSHR	HTR7	0.923
ADCY1	VIPR2	0.923
ADCY1	ADCY9	0.923
GPR84	ADORA2B	0.923
ADCY2	ADCY9	0.923
LHCGR	PTGER2	0.923
AVP	DRD5	0.923
ADCY4	ADRB2	0.923
ADCY2	VIPR2	0.923
GCGR	ADCY3	0.923
CALCA	ADORA2B	0.923
POMC	ADCY2	0.923
ADRB1	ADCY1	0.923
ADCY5	VIP	0.923
CRHR1	ADCY2	0.923
ADCY2	SCT	0.923
ADRB3	CRHR2	0.923
ADCY6	SCTR	0.922
PTH	ADCY3	0.922
POMC	PTGER4	0.922
NPSR1	CALCR	0.922
ADCY5	SCT	0.922
TSHR	POMC	0.922
ADRB1	ADCY3	0.922
ADCY5	GLP1R	0.922
ADCY7	VIPR2	0.922
GCG	ADORA2B	0.922
CRHR1	ADCY1	0.922
CALCRL	ADCY3	0.922
POMC	PTGER2	0.922
ADCY7	VIP	0.922
ADCY1	SCT	0.922
CRHR1	ADCY7	0.922
DRD1	LHCGR	0.922
POMC	CALCR	0.922
POMC	VIPR2	0.922
ADCY1	PTH	0.922
ADCY7	PTGER4	0.922
NPSR1	RAMP1	0.922
HTR7	ADRB2	0.921
AVP	PTGER4	0.921
HTR7	ADCY8	0.921
ADCY2	ADCY8	0.921
ADRB1	HTR7	0.921
ADCY9	PTH	0.921
ADCY8	PTH	0.921
ADCY3	SCT	0.921
POMC	SCTR	0.921
ADCY6	PTGIR	0.921
POMC	ADCY9	0.921
ADM	GCGR	0.921
ADM	CRHR1	0.921
ADCY4	PTH	0.921
ADCYAP1	ADCY2	0.921
ADORA2B	SCT	0.921
ADCY5	GCGR	0.921
ADCY9	GNB3	0.921
GNAS	PTGDR	0.921
DRD5	ADORA2B	0.921
GLP1R	RAMP1	0.921
ADCY1	ADCY8	0.921
ADRB2	SCTR	0.921
POMC	ADCY7	0.921
HTR7	DRD5	0.92
POMC	ADORA2B	0.92
ADORA2B	PTGER4	0.92
ADCYAP1	DRD5	0.92
VIP	ADCY6	0.92
ADCY4	VIPR2	0.92
ADCY4	PTGER2	0.92
CRHR1	ADCY9	0.92
DRD1	ADORA2B	0.92
CALCRL	ADCY4	0.92
CALCR	DRD5	0.92
ADORA2B	PTGER2	0.92
GCGR	ADCY8	0.92
GLP1R	ADCY8	0.92
POMC	ADCY1	0.92
GCGR	ADCY6	0.92
GCG	GNAS	0.92
POMC	VIPR1	0.919
HTR7	ADCY1	0.919
ADRB2	PTGIR	0.919
ADCY5	VIPR2	0.919
VIPR2	ADCY3	0.919
LHCGR	SCTR	0.919
VIP	ADCY4	0.919
ADRB2	PTGDR	0.919
ADCY5	PTH	0.919
GIPR	TSHR	0.919
GIPR	CRH	0.919
ADCYAP1	ADCY7	0.919
ADCY2	PTH	0.919
DRD1	HTR7	0.919
DRD1	CALCA	0.919
ADRB3	ADCY8	0.919
GNG2	ADRB2	0.919
CALCR	LHCGR	0.919
ADCY5	POMC	0.918
POMC	PTGDR	0.918
TSHR	ADCY3	0.918
ADCY5	PTGER2	0.918
GCG	DRD5	0.918
VIP	ADCY9	0.918
CALCRL	ADRB1	0.918
RAMP1	PTGER2	0.918
ADCYAP1	ADCY6	0.918
DRD1	GNAS	0.918
ADCYAP1	ADCY5	0.918
LHCGR	PTH	0.918
CRHR2	PTH	0.918
HTR7	ADCY9	0.918
ADCY5	CRH	0.918
ADCY5	ADCY1	0.918
ADCY7	ADRB3	0.918
CALCR	SCTR	0.918
VIP	ADCY3	0.918
ADCY2	ADCY1	0.918
POMC	ADCY4	0.918
AVP	ADCY6	0.917
TSHR	CALCR	0.917
TSHR	GLP1R	0.917
TAAR8	SCT	0.917
ADRB3	HTR7	0.917
GLP1R	ADRB2	0.917
CALCA	DRD5	0.917
GLP1R	ADCY1	0.917
TSHR	GCGR	0.917
ADRB2	VIPR2	0.917
ADCY7	CRHR2	0.917
ADM	ADRB2	0.917
ADRB3	ADCY4	0.917
VIPR1	ADCY3	0.917
ADCY7	PTH	0.917
ADCYAP1	ADCY3	0.917
DRD1	GLP1R	0.917
ADCY4	ADCY3	0.917
ADCYAP1	ADCY4	0.917
POMC	ADCY6	0.917
ADCYAP1	HTR7	0.917
DRD1	PTH	0.917
ADM	ADRB1	0.917
ADCY2	HTR7	0.917
ADCY9	VIPR2	0.917
ADRB3	PTGIR	0.917
ADRB3	ADCY9	0.917
ADCY5	ADCY8	0.917
ADCY6	PTGER4	0.917
GIPR	RAMP1	0.917
GLP1R	ADRB3	0.917
ADRB3	ADCY3	0.917
ADCY9	SCTR	0.917
ADCY5	VIPR1	0.917
GCG	DRD1	0.917
CALCRL	ADCY2	0.917
GNG2	ADCY4	0.917
LHCGR	SCT	0.917
TSHR	SCT	0.917
CALCRL	POMC	0.917
ADRB1	PTGER2	0.917
ADCY5	HTR7	0.917
GIPR	GNAS	0.916
ADORA2B	PTGIR	0.916
CRHR1	ADORA2B	0.916
GCGR	NPS	0.916
AVP	CALCR	0.916
ADRB2	PTGER4	0.916
ADCY2	ADCY3	0.916
ADRB1	PTGIR	0.916
ADRB1	DRD5	0.916
GCGR	DRD1	0.916
ADCY7	SCTR	0.916
GIPR	ADCYAP1	0.916
ADM	PTGIR	0.916
CALCRL	LHCGR	0.916
CALCR	ADRB2	0.916
ADM	SCTR	0.916
ADCY5	PTGDR	0.916
DRD5	PTGDR	0.916
ADCY5	CALCA	0.916
CALCR	ADCY8	0.916
ADCY7	GNB3	0.915
VIPR1	ADCY1	0.915
PTGIR	PTH	0.915
ADRB3	ADCY2	0.915
ADCY6	VIPR2	0.915
AVP	PTGIR	0.915
GNAS	PTGER4	0.915
GNAS	CALCA	0.915
HTR7	ADCY3	0.915
GNAS	CRH	0.915
ADM	ADORA2B	0.915
ADCY4	SCTR	0.915
NPS	ADCY3	0.915
ADCY2	GNG2	0.915
ADCY6	ADCY3	0.915
GCGR	ADRB3	0.915
VIPR1	ADCY4	0.915
GCG	NPSR1	0.915
GPR84	CALCRL	0.915
HTR7	ADCY4	0.915
VIPR1	ADCY9	0.915
ADCYAP1	ADRB3	0.915
GLP1R	DRD5	0.915
ADCY7	ADCY3	0.915
NPS	ADCY8	0.915
ADCY8	GNB3	0.915
ADCY5	ADCY2	0.915
ADCYAP1	ADRB1	0.915
TSHR	CRHR1	0.914
ADCY8	CRH	0.914
GLP1R	ADCY2	0.914
NPSR1	LHCGR	0.914
ADRB3	ADCY1	0.914
CALCA	PTGDR	0.914
CALCRL	CRHR1	0.914
ADRB3	ADORA2B	0.914
PTGER4	PTGIR	0.914
ADRB3	DRD5	0.914
ADORA2B	LHCGR	0.914
ADCY5	CRHR2	0.914
CRHR1	LHCGR	0.914
CALCA	ADCY6	0.914
HTR7	ADCY6	0.914
TSHR	NPSR1	0.914
ADCY5	ADCY4	0.914
ADCY7	HTR7	0.914
DRD1	ADRB3	0.914
ADORA2B	CRH	0.914
ADRB1	ADORA2B	0.914
ADCY4	PTGER4	0.914
CRHR1	VIPR1	0.914
GCGR	LHCGR	0.914
DRD1	VIPR2	0.913
CALCR	ADORA2B	0.913
CALCRL	ADORA2B	0.913
ADCY7	VIPR1	0.913
GCGR	CALCR	0.913
CALCA	ADCY1	0.913
DRD1	VIPR1	0.913
DRD5	SCT	0.913
ADCYAP1	PTGIR	0.913
DRD1	PTGIR	0.913
AVP	LHCGR	0.913
DRD5	ADRB2	0.913
ADCY5	GNG2	0.913
PTGER4	ADCY1	0.913
GCGR	CRHR1	0.913
VIPR1	ADCY6	0.913
ADCYAP1	ADRB2	0.913
CALCRL	ADRB3	0.913
ADCY5	ADCY3	0.913
PTGER4	LHCGR	0.913
HTR7	PTGER4	0.913
ADRB1	CALCR	0.913
ADCY7	ADCY8	0.913
CALCRL	PTGER4	0.913
ADCY4	ADCY8	0.913
ADM	CRHR2	0.913
TSHR	PTGER2	0.913
GCGR	NPSR1	0.913
ADCY4	ADCY6	0.913
CALCA	ADCY3	0.913
VIPR1	ADCY8	0.913
ADCY2	LHCGR	0.913
ADCY7	ADCY1	0.913
TSHR	CRH	0.913
GNAS	DRD5	0.913
ADRB2	ADORA2B	0.913
CALCRL	AVP	0.913
NPS	ADCY1	0.913
CRHR1	CALCR	0.913
HTR7	PTH	0.913
ADCY6	GNB3	0.913
ADCY1	ADCY3	0.913
ADCY2	VIPR1	0.913
DRD1	ADRB1	0.913
ADRB3	SCTR	0.912
ADRB2	RAMP1	0.912
ADCY4	ADCY1	0.912
ADCY8	VIPR2	0.912
ADCY7	CALCA	0.912
ADM	ADRB3	0.912
HTR7	VIPR1	0.912
ADCY1	GNB3	0.912
TAAR8	SCTR	0.912
ADORA2B	RAMP1	0.912
ADCY5	AVP	0.912
CALCA	ADCY9	0.912
ADCY7	ADCY6	0.912
CALCA	ADCY8	0.912
GCGR	ADORA2B	0.912
CRHR2	VIPR1	0.912
ADM	GLP1R	0.912
LHCGR	CRH	0.912
CALCA	ADCY4	0.912
DRD1	SCT	0.912
GLP1R	HTR7	0.912
TSHR	ADCY9	0.912
PTGER4	ADCY3	0.912
PTGDR	PTGER4	0.912
TSHR	CALCRL	0.912
ADCY6	PTGER2	0.912
ADCY5	PTGER4	0.912
ADCY5	SCTR	0.912
ADORA2B	GNB3	0.912
ADCY2	CALCA	0.912
CALCRL	VIPR2	0.912
ADCY9	CRH	0.912
GCGR	ADRB1	0.912
DRD1	SCTR	0.912
DRD1	NPSR1	0.911
CRHR1	ADCY4	0.911
ADRB1	SCTR	0.911
ADCY7	PTGER2	0.911
CALCRL	VIPR1	0.911
TSHR	ADRB3	0.911
PTGER4	SCTR	0.911
CRHR1	VIPR2	0.911
TSHR	ADRB1	0.911
ADRB3	LHCGR	0.911
GLP1R	ADCY9	0.911
ADCY2	GNB3	0.911
ADCY5	ADCY7	0.911
ADCY2	CRHR2	0.911
NPS	ADCY7	0.911
ADCYAP1	ADCY9	0.911
NPSR1	DRD5	0.911
HTR7	ADORA2B	0.911
GPR84	SCTR	0.911
CRHR1	GLP1R	0.911
CRHR2	RAMP1	0.911
DRD1	ADRB2	0.911
NPS	GNAS	0.911
GLP1R	ADCY6	0.911
ADCY8	ADCY3	0.911
CRHR2	ADCY8	0.911
GNG2	ADCY9	0.911
ADORA2B	SCTR	0.911
DRD1	DRD5	0.911
POMC	RAMP1	0.911
CALCR	VIPR2	0.911
NPS	ADCY9	0.91
NPSR1	ADORA2B	0.91
CRHR1	SCTR	0.91
AVP	SCTR	0.91
ADCY6	ADCY8	0.91
CRHR2	ADORA2B	0.91
DRD5	PTH	0.91
CRH	RAMP1	0.91
P2RY11	PTGER2	0.91
HTR7	VIPR2	0.91
NPS	LHCGR	0.91
DRD1	PTGDR	0.91
TSHR	DRD1	0.91
PTGIR	SCT	0.91
HTR7	GNB3	0.91
CALCRL	SCTR	0.91
ADM	HTR7	0.91
NPS	PTGIR	0.91
VIPR1	PTGER4	0.91
DRD1	CALCR	0.91
TSHR	GCG	0.91
NPS	PTGER4	0.91
DRD1	GNG2	0.91
GCG	PTGER4	0.91
ADCY5	NPS	0.91
VIP	PTGER4	0.91
ADCY5	GNB3	0.91
TSHR	TAAR8	0.91
CALCRL	GCGR	0.91
NPSR1	ADRB2	0.91
AVP	ADORA2B	0.91
TAAR8	ADCY3	0.909
CALCRL	CRHR2	0.909
GLP1R	ADCY3	0.909
DRD5	SCTR	0.909
PTGDR	ADCY3	0.909
GIPR	VIPR2	0.909
GIPR	VIPR1	0.909
ADORA2B	PTH	0.909
GCGR	VIPR1	0.909
GLP1R	CALCR	0.909
GLP1R	ADRB1	0.909
CALCR	ADCY3	0.909
CALCR	CRHR2	0.909
ADCY4	GNB3	0.909
GLP1R	ADORA2B	0.909
PTGER2	SCTR	0.909
GPR84	RAMP1	0.909
ADCY7	LHCGR	0.909
CRHR2	VIPR2	0.909
GLP1R	ADCY4	0.909
ADCY7	CALCR	0.909
GLP1R	VIPR2	0.909
CALCR	VIPR1	0.909
HTR7	P2RY11	0.909
AVP	ADCY3	0.909
CALCRL	GLP1R	0.909
PTGIR	VIPR2	0.909
GCGR	VIPR2	0.909
PTGER4	ADCY9	0.909
NPS	ADCY4	0.909
ADCY7	GLP1R	0.909
CALCR	ADCY2	0.909
TSHR	CRHR2	0.909
TSHR	ADCY8	0.909
VIPR1	ADORA2B	0.908
TSHR	ADCY5	0.908
GCGR	CRHR2	0.908
AVP	ADCY1	0.908
VIP	LHCGR	0.908
GCG	PTGIR	0.908
NPSR1	HTR7	0.908
TSHR	ADORA2B	0.908
ADCY6	PTGDR	0.908
ADCYAP1	ADORA2B	0.908
GLP1R	VIPR1	0.908
ADRB1	VIPR2	0.908
VIPR1	VIPR2	0.908
GIPR	CRHR1	0.908
DRD1	GNB3	0.908
ADCY3	SCTR	0.908
TSHR	ADCY2	0.908
PTGIR	SCTR	0.908
VIPR1	P2RY11	0.908
NPS	ADCY2	0.908
ADCY3	GNB3	0.908
GPR84	NPSR1	0.908
NPS	ADCY6	0.908
GIPR	CALCRL	0.908
PTGDR	PTGER2	0.908
P2RY11	PTGER4	0.908
AVP	VIPR1	0.908
ADCY2	ADCY6	0.908
CALCR	ADCY4	0.908
AVP	GNAS	0.908
PTGIR	CRH	0.908
ADRB1	RAMP1	0.908
GIPR	ADORA2B	0.908
DRD5	TAAR8	0.908
ADCYAP1	GNAS	0.908
POMC	GNB3	0.908
ADCY6	TAAR8	0.908
ADCY1	CRH	0.908
CRHR2	ADCY4	0.908
CRHR1	ADCY3	0.907
GCG	LHCGR	0.907
GIPR	ADRB2	0.907
ADCY6	ADCY1	0.907
ADCY7	CRH	0.907
GCGR	DRD5	0.907
PTGIR	PTGER2	0.907
CRHR2	PTGER4	0.907
GIPR	DRD1	0.907
ADCY7	PTGDR	0.907
TSHR	AVP	0.907
CALCR	PTGER4	0.907
PTGDR	ADCY1	0.907
DRD1	PTGER4	0.907
GIPR	GLP1R	0.907
GPR84	PTGER4	0.907
CALCRL	DRD5	0.907
CRHR1	ADCY6	0.907
ADCY2	PTGDR	0.907
P2RY11	ADRB2	0.907
ADORA2B	PTGDR	0.907
ADCY4	PTGIR	0.907
ADRB1	PTGER4	0.907
ADRB3	PTGER4	0.907
GNG2	ADORA2B	0.907
ADRB3	RAMP1	0.907
CALCA	PTGER2	0.907
ADORA2B	VIPR2	0.907
PTGDR	PTGIR	0.907
ADORA2B	TAAR8	0.907
CALCR	HTR7	0.907
AVP	GLP1R	0.907
ADRB1	P2RY11	0.906
CALCA	TAAR8	0.906
CRHR1	GNB3	0.906
PTGER4	ADCY8	0.906
GLP1R	CRHR2	0.906
CRHR2	ADCY1	0.906
GLP1R	LHCGR	0.906
GIPR	CALCR	0.906
ADCY2	CRH	0.906
GNAS	VIPR2	0.906
CRHR2	ADCY6	0.906
GIPR	SCTR	0.906
GLP1R	SCTR	0.906
PTGER4	RAMP1	0.906
GCGR	SCTR	0.906
ADCY7	ADCY4	0.906
GPR84	SCT	0.906
TSHR	VIPR2	0.906
ADCY7	PTGIR	0.906
ADCY2	SCTR	0.906
GCGR	HTR7	0.906
GPR84	POMC	0.906
GPR84	ADM	0.906
ADCY1	SCTR	0.906
ADRB3	P2RY11	0.906
CRHR1	CRHR2	0.906
ADRB3	ADRB2	0.906
TSHR	VIP	0.906
GNG2	PTGDR	0.906
PTGDR	ADCY8	0.906
CRHR1	PTGDR	0.906
ADCY5	CALCR	0.906
P2RY11	VIPR2	0.906
CALCRL	GNAS	0.906
GIPR	NPS	0.906
NPSR1	ADCY3	0.906
CALCRL	ADCY1	0.906
ADCY5	ADCY6	0.906
CALCR	ADRB3	0.906
NPSR1	PTGER4	0.906
PTH	PTGER2	0.906
DRD5	VIPR2	0.906
CRHR2	ADCY3	0.906
ADRB3	PTGDR	0.906
ADRB1	PTGDR	0.906
NPS	PTGER2	0.905
CRHR2	SCTR	0.905
ADM	NPSR1	0.905
TSHR	ADCY7	0.905
ADRB1	ADRB2	0.905
LHCGR	PTGIR	0.905
CALCA	P2RY11	0.905
GPR84	CALCR	0.905
CALCRL	ADCY6	0.905
CALCR	ADCY6	0.905
GLP1R	PTGER4	0.905
GIPR	ADRB3	0.905
GIPR	ADCY9	0.905
TSHR	ADCY4	0.905
CRHR1	PTGER2	0.905
GPR84	ADCY4	0.905
NPSR1	GLP1R	0.905
GNAS	CALCR	0.905
HTR7	SCTR	0.905
CALCRL	DRD1	0.905
GCGR	GLP1R	0.905
CALCR	ADCY1	0.905
GIPR	CRHR2	0.905
NPSR1	ADRB1	0.905
CRH	ADCY3	0.905
GPR84	PTGER2	0.905
DRD5	LHCGR	0.905
GIPR	ADCY1	0.905
P2RY11	SCT	0.905
LHCGR	VIPR2	0.905
PTGDR	TAAR8	0.905
TSHR	NPS	0.905
GCGR	PTGER2	0.905
AVP	ADCY8	0.905
ADCY4	LHCGR	0.905
ADCY9	PTGER2	0.905
ADCY5	CALCRL	0.905
GNG2	DRD5	0.905
ADRB1	ADRB3	0.905
ADCY2	PTGER4	0.905
PTGER4	VIPR2	0.905
GPR84	LHCGR	0.904
ADCY3	PTGER2	0.904
ADCY1	PTGER2	0.904
GPR84	TSHR	0.904
TSHR	LHCGR	0.904
CRHR1	GNAS	0.904
ADCY8	PTGER2	0.904
VIPR2	SCTR	0.904
TSHR	PTGIR	0.904
CALCRL	PTGIR	0.904
TSHR	DRD5	0.904
NPSR1	PTGER2	0.904
LHCGR	ADCY9	0.904
TSHR	ADCY6	0.904
ADCY1	PTGIR	0.904
GCG	TAAR8	0.904
GIPR	GCGR	0.904
AVP	ADCY2	0.904
ADM	LHCGR	0.904
HTR7	PTGDR	0.904
CALCRL	HTR7	0.904
PTGIR	ADCY3	0.904
GPR84	ADCY7	0.904
ADCY6	LHCGR	0.904
PTGIR	ADCY8	0.904
GIPR	ADM	0.904
ADRB3	VIPR2	0.904
DRD5	PTGIR	0.904
GNG2	ADCY8	0.904
GNG2	PTGER4	0.904
ADCY2	PTGER2	0.904
TSHR	PTGER4	0.904
GNAS	CRHR2	0.904
NPS	P2RY11	0.904
ADRB2	TAAR8	0.904
ADRB3	PTGER2	0.904
NPSR1	ADCY2	0.903
ADCY5	RAMP1	0.903
GLP1R	TAAR8	0.903
ADCY7	P2RY11	0.903
GCGR	TAAR8	0.903
DRD1	TAAR8	0.903
PTGER2	SCT	0.903
DRD1	RAMP1	0.903
GIPR	NPSR1	0.903
GCG	GNB3	0.903
TSHR	VIPR1	0.903
CALCRL	CALCR	0.903
ADCY7	ADCY2	0.903
NPSR1	ADCY4	0.903
NPS	GNB3	0.903
NPSR1	ADCY8	0.903
VIPR1	SCTR	0.903
P2RY11	PTGIR	0.903
GLP1R	GNAS	0.903
ADCY7	GNG2	0.903
LHCGR	TAAR8	0.903
ADCYAP1	PTGER4	0.903
CRHR2	PTGER2	0.903
NPSR1	P2RY11	0.903
PTGDR	ADCY9	0.903
GNAS	VIP	0.903
HTR7	TAAR8	0.903
ADCY5	LHCGR	0.903
ADCY4	CRH	0.903
ADCY4	TAAR8	0.903
PTGER4	SCT	0.903
VIP	P2RY11	0.903
ADCYAP1	GNG2	0.903
VIPR1	DRD5	0.903
DRD5	PTGER4	0.903
PTGDR	CRH	0.903
ADCY1	LHCGR	0.903
GIPR	TAAR8	0.903
AVP	GNB3	0.903
AVP	PTGDR	0.903
PTGDR	LHCGR	0.903
NPSR1	GNB3	0.903
GIPR	HTR7	0.903
NPSR1	ADCY1	0.903
ADCY7	NPSR1	0.903
NPSR1	ADRB3	0.903
NPSR1	ADCY6	0.903
ADCY2	PTGIR	0.903
ADCY5	NPSR1	0.903
GIPR	AVP	0.903
PTGIR	TAAR8	0.903
P2RY11	DRD5	0.903
LHCGR	ADCY3	0.902
VIPR1	LHCGR	0.902
GCGR	PTGDR	0.902
GIPR	PTGIR	0.902
ADCY9	TAAR8	0.902
VIP	TAAR8	0.902
ADRB1	VIPR1	0.902
GPR84	ADCY5	0.902
GCG	PTGER2	0.902
LHCGR	ADCY8	0.902
GLP1R	PTGER2	0.902
ADM	DRD5	0.902
ADCY6	CRH	0.902
GCGR	PTGIR	0.902
GNG2	ADCY6	0.902
CALCRL	PTGER2	0.902
NPS	TAAR8	0.902
PTGDR	PTH	0.902
DRD1	P2RY11	0.902
ADCY1	TAAR8	0.902
ADCY7	TAAR8	0.902
ADCY2	TAAR8	0.902
CRHR2	LHCGR	0.902
GPR84	ADCY2	0.902
CALCR	PTGDR	0.902
P2RY11	ADCY8	0.902
GPR84	ADCY9	0.902
PTGIR	RAMP1	0.902
VIPR1	PTGDR	0.902
NPS	PTGDR	0.902
GIPR	PTGDR	0.902
ADCY8	TAAR8	0.902
GPR84	ADCY1	0.902
ADCY5	TAAR8	0.902
ADCYAP1	TSHR	0.902
GPR84	ADCY8	0.902
GCGR	GNAS	0.902
GNB3	SCTR	0.902
CRH	GNB3	0.902
NPSR1	ADCY9	0.902
GPR84	ADCY6	0.902
ADCY2	ADCY4	0.902
ADRB1	TAAR8	0.902
VIPR1	ADRB2	0.902
DRD1	PTGER2	0.902
GPR84	PTGIR	0.902
GLP1R	PTGDR	0.902
ADCYAP1	TAAR8	0.902
VIP	PTGER2	0.902
ADCY9	PTGIR	0.902
AVP	RAMP1	0.902
GPR84	ADCY3	0.902
GLP1R	PTGIR	0.902
GIPR	PTGER2	0.902
NPSR1	TAAR8	0.901
GPR84	PTGDR	0.901
HTR7	RAMP1	0.901
ADCY5	P2RY11	0.901
TSHR	GNB3	0.901
CALCR	TAAR8	0.901
GCGR	AVP	0.901
CALCRL	ADCY9	0.901
CRH	TAAR8	0.901
GIPR	ADCY2	0.901
TSHR	PTGDR	0.901
CALCR	ADCY9	0.901
ADM	PTGER4	0.901
VIP	GNB3	0.901
ADCY2	RAMP1	0.901
DRD5	PTGER2	0.901
CALCRL	P2RY11	0.901
PTGDR	SCTR	0.901
ADCYAP1	P2RY11	0.901
VIP	GNG2	0.901
GPR84	ADRB2	0.901
VIPR1	PTGIR	0.901
ADRB3	TAAR8	0.901
AVP	ADCY9	0.901
ADRB3	VIPR1	0.901
GNG2	ADCY3	0.901
ADM	DRD1	0.901
CALCRL	TAAR8	0.901
AVP	ADCY4	0.901
POMC	PTGIR	0.901
CRHR1	P2RY11	0.901
CRHR1	PTGER4	0.901
GIPR	ADCY7	0.901
GPR84	TAAR8	0.901
DRD5	GNB3	0.901
GIPR	ADCY6	0.901
ADM	PTGER2	0.901
GNG2	CRH	0.901
GNAS	SCTR	0.901
GCG	PTGDR	0.901
GIPR	ADCY4	0.901
GCG	GNG2	0.901
GNB3	SCT	0.9
CALCR	GNB3	0.9
P2RY11	ADCY3	0.9
ADCY3	RAMP1	0.9
RAMP1	GNB3	0.9
PTGDR	GNB3	0.9
GLP1R	GNG2	0.9
ADM	ADCY5	0.9
ADM	ADCY3	0.9
GIPR	GNB3	0.9
ADCY6	RAMP1	0.9
POMC	GNG2	0.9
CRHR2	PTGDR	0.9
ADCY9	RAMP1	0.9
GPR84	CRH	0.9
GNG2	VIPR2	0.9
GPR84	GCGR	0.9
VIPR1	GNB3	0.9
CALCR	PTGIR	0.9
P2RY11	PTGDR	0.9
ADRB1	GNG2	0.9
GPR84	VIPR1	0.9
CRHR2	PTGIR	0.9
ADCYAP1	PTGDR	0.9
TSHR	RAMP1	0.9
P2RY11	LHCGR	0.9
HTR7	PTGER2	0.9
PTGER4	GNB3	0.9
POMC	TAAR8	0.9
CALCR	P2RY11	0.9
TSHR	P2RY11	0.9
GIPR	GPR84	0.9
GCGR	P2RY11	0.9
AVP	P2RY11	0.9
P2RY11	PTH	0.9
TAAR8	PTGER2	0.9
CALCR	PTGER2	0.9
NPSR1	PTGIR	0.9
P2RY11	GNB3	0.9
CALCRL	GNB3	0.9
ADCY1	RAMP1	0.9
CRHR1	GNG2	0.9
TSHR	GNG2	0.9
GNG2	PTGIR	0.9
PTGER4	TAAR8	0.9
CRHR2	GNG2	0.9
VIP	PTGDR	0.9
ADCY7	RAMP1	0.9
ADM	ADCY1	0.9
GPR84	GNG2	0.9
ADM	GNG2	0.9
ADM	TAAR8	0.9
GNG2	LHCGR	0.9
ADRB3	GNG2	0.9
P2RY11	ADCY9	0.9
P2RY11	TAAR8	0.9
TAAR8	RAMP1	0.9
GPR84	DRD1	0.9
CALCA	LHCGR	0.9
GNG2	VIPR1	0.9
GPR84	ADRB1	0.9
HTR7	GNG2	0.9
ADCYAP1	GPR84	0.9
GCGR	PTGER4	0.9
ADCY4	RAMP1	0.9
ADCY7	AVP	0.9
CALCRL	GNG2	0.9
GPR84	CRHR1	0.9
ADM	ADCY4	0.9
GPR84	DRD5	0.9
VIPR2	GNB3	0.9
GLP1R	P2RY11	0.9
CRHR2	GNB3	0.9
GNG2	TAAR8	0.9
LHCGR	RAMP1	0.9
P2RY11	SCTR	0.9
VIPR1	PTGER2	0.9
DRD5	RAMP1	0.9
GNAS	TAAR8	0.9
GCGR	GNG2	0.9
PTGER2	GNB3	0.9
ADCYAP1	PTGER2	0.9
GPR84	CRHR2	0.9
AVP	PTGER2	0.9
PTH	TAAR8	0.9
PTH	GNB3	0.9
PTGDR	SCT	0.9
ADM	ADCY7	0.9
GCGR	GNB3	0.9
ADM	ADCY6	0.9
GNAS	RAMP1	0.9
ADM	ADCY9	0.9
PTGIR	GNB3	0.9
GIPR	DRD5	0.9
ADM	ADCY2	0.9
CRHR2	P2RY11	0.9
LHCGR	GNB3	0.9
PTGDR	VIPR2	0.9
TAAR8	GNB3	0.9
VIPR2	PTGER2	0.9
POMC	P2RY11	0.9
GIPR	P2RY11	0.9
GNG2	SCTR	0.9
GNG2	SCT	0.9
GPR84	AVP	0.9
P2RY11	RAMP1	0.9
GNAS	P2RY11	0.9
P2RY11	ADCY1	0.9
AVP	TAAR8	0.9
GNG2	P2RY11	0.9
P2RY11	CRH	0.9
GPR84	GNB3	0.9
GPR84	VIP	0.9
AVP	GNG2	0.9
ADCYAP1	LHCGR	0.9
GPR84	GLP1R	0.9
CALCRL	PTGDR	0.9
GNAS	PTGER2	0.9
GIPR	PTGER4	0.9
NPSR1	GNG2	0.9
NPS	GNG2	0.9
GLP1R	GNB3	0.9
P2RY11	ADCY6	0.9
GNAS	VIPR1	0.9
GNG2	PTH	0.9
GPR84	CALCA	0.9
GPR84	NPS	0.9
GPR84	ADRB3	0.9
ADM	PTGDR	0.9
GPR84	HTR7	0.9
CRHR1	PTGIR	0.9
CALCA	GNB3	0.9
TSHR	ADM	0.9
ADM	P2RY11	0.9
TAAR8	VIPR2	0.9
GPR84	P2RY11	0.9
GNAS	PTGIR	0.9
CRHR1	TAAR8	0.9
P2RY11	ADCY4	0.9
ADM	ADCY8	0.9
GCG	P2RY11	0.9
CALCR	GNG2	0.9
VIPR1	TAAR8	0.9
GPR84	GNAS	0.9
ADCY2	P2RY11	0.9
ADCY8	RAMP1	0.9
ADM	GNAS	0.9
GPR84	PTH	0.9
GNG2	CALCA	0.9
ADM	GNB3	0.9
NPSR1	GNAS	0.9
GNG2	RAMP1	0.9
PTGDR	RAMP1	0.9
GIPR	GNG2	0.9
GPR84	VIPR2	0.9
CRHR2	TAAR8	0.9

Gene Ontology Semantic Similarity

Download Tab separated file

#	5443 (POMC)	10203 (CALCRL)	1394 (CRHR1)	2641 (GCG)	133 (ADM)	1395 (CRHR2)	7432 (VIP)	116 (ADCYAP1)	796 (CALCA)	551 (AVP)	6343 (SCT)	799 (CALCR)	7433 (VIPR1)	7434 (VIPR2)	2696 (GIPR)	2778 (GNAS)	1816 (DRD5)	3363 (HTR7)	1812 (DRD1)	2642 (GCGR)	5741 (PTH)	111 (ADCY5)	113 (ADCY7)	108 (ADCY2)	154 (ADRB2)	196883 (ADCY4)	1392 (CRH)	155 (ADRB3)	7253 (TSHR)	2740 (GLP1R)	387129 (NPSR1)	5032 (P2RY11)	153 (ADRB1)	112 (ADCY6)	54331 (GNG2)	10267 (RAMP1)	114 (ADCY8)	5734 (PTGER4)	115 (ADCY9)	53831 (GPR84)	107 (ADCY1)	3973 (LHCGR)	109 (ADCY3)	83551 (TAAR8)	5739 (PTGIR)	5729 (PTGDR)	5732 (PTGER2)	2784 (GNB3)	6344 (SCTR)
5443 (POMC)	1.00	0.43	0.48	0.81	0.79	0.50	0.74	0.81	0.71	0.66	0.89	0.46	0.50	0.21	0.47	0.71	0.40	0.11	0.51	0.21	0.70	0.41	0.14	0.38	0.45	0.56	0.83	0.45	0.49	0.47	0.09	0.13	0.47	0.55	0.58	0.44	0.11	0.57	0.14	0.08	0.11	0.24	0.14	0.09	0.21	0.57	0.09	0.57	0.22
10203 (CALCRL)	0.43	1.00	0.74	0.53	0.37	0.74	0.48	0.50	0.48	0.34	0.41	0.82	0.82	0.76	0.82	0.48	0.57	0.58	0.64	0.66	0.44	0.32	0.17	0.32	0.59	0.40	0.51	0.63	0.73	0.81	0.78	0.50	0.61	0.42	0.43	0.88	0.12	0.60	0.17	0.56	0.12	0.66	0.17	0.58	0.26	0.60	0.70	0.41	0.72
1394 (CRHR1)	0.48	0.74	1.00	0.59	0.44	0.99	0.54	0.56	0.55	0.39	0.48	0.74	0.87	0.80	0.87	0.52	0.55	0.53	0.63	0.70	0.48	0.37	0.17	0.36	0.61	0.46	0.57	0.61	0.71	0.86	0.69	0.51	0.59	0.48	0.49	0.70	0.13	0.61	0.17	0.44	0.13	0.62	0.17	0.48	0.26	0.61	0.60	0.48	0.78
2641 (GCG)	0.81	0.53	0.59	1.00	0.83	0.62	0.87	0.86	0.87	0.68	0.90	0.56	0.62	0.25	0.57	0.72	0.50	0.14	0.63	0.27	0.73	0.53	0.17	0.49	0.57	0.70	0.93	0.57	0.60	0.57	0.12	0.16	0.56	0.69	0.73	0.53	0.14	0.72	0.17	0.10	0.14	0.30	0.17	0.12	0.26	0.72	0.11	0.72	0.27
133 (ADM)	0.79	0.37	0.44	0.83	1.00	0.46	0.76	0.80	0.75	0.62	0.91	0.39	0.46	0.20	0.41	0.67	0.37	0.12	0.48	0.21	0.66	0.44	0.14	0.39	0.41	0.56	0.84	0.41	0.44	0.41	0.09	0.14	0.43	0.55	0.60	0.37	0.13	0.58	0.14	0.09	0.13	0.23	0.14	0.11	0.21	0.58	0.09	0.58	0.21
1395 (CRHR2)	0.50	0.74	0.99	0.62	0.46	1.00	0.57	0.58	0.58	0.40	0.51	0.74	0.87	0.79	0.87	0.53	0.59	0.59	0.66	0.68	0.50	0.39	0.17	0.38	0.61	0.48	0.60	0.63	0.75	0.86	0.69	0.56	0.60	0.50	0.52	0.70	0.13	0.66	0.17	0.50	0.13	0.64	0.17	0.55	0.26	0.66	0.60	0.50	0.76
7432 (VIP)	0.74	0.48	0.54	0.87	0.76	0.57	1.00	0.91	0.76	0.67	0.85	0.50	0.57	0.24	0.52	0.64	0.46	0.14	0.58	0.25	0.76	0.50	0.17	0.46	0.52	0.66	0.94	0.52	0.55	0.52	0.12	0.16	0.51	0.65	0.69	0.48	0.14	0.67	0.17	0.10	0.14	0.28	0.17	0.11	0.26	0.67	0.11	0.67	0.25
116 (ADCYAP1)	0.81	0.50	0.56	0.86	0.80	0.58	0.91	1.00	0.76	0.71	0.86	0.53	0.58	0.24	0.54	0.70	0.47	0.13	0.59	0.25	0.76	0.48	0.17	0.46	0.54	0.65	0.89	0.53	0.56	0.54	0.12	0.15	0.54	0.65	0.68	0.51	0.13	0.66	0.17	0.09	0.13	0.28	0.17	0.11	0.26	0.66	0.11	0.66	0.25
796 (CALCA)	0.71	0.48	0.55	0.87	0.75	0.58	0.76	0.76	1.00	0.56	0.78	0.51	0.58	0.24	0.53	0.69	0.47	0.14	0.60	0.26	0.63	0.53	0.17	0.48	0.54	0.69	0.78	0.53	0.56	0.52	0.12	0.17	0.53	0.68	0.73	0.48	0.15	0.71	0.17	0.11	0.15	0.29	0.17	0.12	0.26	0.71	0.11	0.71	0.26
551 (AVP)	0.66	0.34	0.39	0.68	0.62	0.40	0.67	0.71	0.56	1.00	0.69	0.35	0.39	0.18	0.37	0.59	0.32	0.11	0.41	0.21	0.58	0.37	0.21	0.35	0.39	0.47	0.73	0.37	0.39	0.37	0.09	0.13	0.40	0.47	0.48	0.34	0.15	0.45	0.21	0.08	0.15	0.20	0.21	0.09	0.26	0.45	0.09	0.47	0.18
6343 (SCT)	0.89	0.41	0.48	0.90	0.91	0.51	0.85	0.86	0.78	0.69	1.00	0.44	0.50	0.21	0.46	0.72	0.41	0.12	0.51	0.22	0.74	0.46	0.14	0.41	0.44	0.60	0.92	0.44	0.48	0.46	0.09	0.14	0.47	0.58	0.63	0.42	0.13	0.62	0.14	0.09	0.13	0.25	0.14	0.11	0.21	0.62	0.09	0.61	0.23
799 (CALCR)	0.46	0.82	0.74	0.56	0.39	0.74	0.50	0.53	0.51	0.35	0.44	1.00	0.85	0.75	0.83	0.49	0.54	0.52	0.61	0.71	0.46	0.33	0.17	0.34	0.57	0.42	0.54	0.58	0.74	0.84	0.76	0.45	0.56	0.44	0.45	0.83	0.12	0.59	0.17	0.62	0.12	0.66	0.17	0.53	0.26	0.59	0.45	0.43	0.75
7433 (VIPR1)	0.50	0.82	0.87	0.62	0.46	0.87	0.57	0.58	0.58	0.39	0.50	0.85	1.00	0.91	0.94	0.53	0.61	0.60	0.68	0.79	0.49	0.38	0.17	0.37	0.63	0.48	0.59	0.65	0.79	0.95	0.92	0.51	0.62	0.49	0.51	0.76	0.13	0.69	0.17	0.65	0.13	0.72	0.17	0.60	0.26	0.69	0.60	0.49	0.85
7434 (VIPR2)	0.21	0.76	0.80	0.25	0.20	0.79	0.24	0.24	0.24	0.18	0.21	0.75	0.91	1.00	0.88	0.22	0.56	0.75	0.54	0.83	0.23	0.17	0.12	0.18	0.51	0.21	0.25	0.55	0.70	0.88	0.92	0.62	0.48	0.21	0.22	0.66	0.10	0.56	0.12	0.77	0.10	0.79	0.12	0.78	0.17	0.56	0.70	0.22	0.94
2696 (GIPR)	0.47	0.82	0.87	0.57	0.41	0.87	0.52	0.54	0.53	0.37	0.46	0.83	0.94	0.88	1.00	0.50	0.63	0.65	0.70	0.79	0.47	0.35	0.17	0.35	0.65	0.44	0.55	0.67	0.81	0.97	0.92	0.58	0.64	0.46	0.47	0.76	0.13	0.70	0.17	0.66	0.13	0.73	0.17	0.65	0.26	0.70	0.66	0.45	0.85
2778 (GNAS)	0.71	0.48	0.52	0.72	0.67	0.53	0.64	0.70	0.69	0.59	0.72	0.49	0.53	0.22	0.50	1.00	0.43	0.12	0.54	0.23	0.63	0.43	0.19	0.41	0.51	0.58	0.69	0.50	0.52	0.50	0.12	0.14	0.53	0.58	0.73	0.48	0.13	0.57	0.19	0.08	0.13	0.26	0.19	0.10	0.26	0.57	0.11	0.72	0.22
1816 (DRD5)	0.40	0.57	0.55	0.50	0.37	0.59	0.46	0.47	0.47	0.32	0.41	0.54	0.61	0.56	0.63	0.43	1.00	0.54	0.98	0.45	0.40	0.31	0.14	0.36	0.54	0.39	0.48	0.60	0.62	0.62	0.59	0.49	0.56	0.40	0.42	0.50	0.11	0.57	0.14	0.45	0.11	0.52	0.14	0.51	0.21	0.57	0.51	0.40	0.50
3363 (HTR7)	0.11	0.58	0.53	0.14	0.12	0.59	0.14	0.13	0.14	0.11	0.12	0.52	0.60	0.75	0.65	0.12	0.54	1.00	0.49	0.56	0.16	0.11	0.12	0.11	0.38	0.14	0.14	0.49	0.66	0.64	0.78	0.83	0.41	0.13	0.14	0.52	0.11	0.51	0.12	0.73	0.11	0.66	0.12	0.84	0.18	0.51	0.70	0.14	0.67
1812 (DRD1)	0.51	0.64	0.63	0.63	0.48	0.66	0.58	0.59	0.60	0.41	0.51	0.61	0.68	0.54	0.70	0.54	0.98	0.49	1.00	0.45	0.50	0.40	0.17	0.42	0.61	0.51	0.61	0.66	0.68	0.69	0.59	0.45	0.63	0.52	0.54	0.57	0.13	0.66	0.17	0.40	0.13	0.53	0.17	0.46	0.26	0.66	0.51	0.52	0.49
2642 (GCGR)	0.21	0.66	0.70	0.27	0.21	0.68	0.25	0.25	0.26	0.21	0.22	0.71	0.79	0.83	0.79	0.23	0.45	0.56	0.45	1.00	0.25	0.19	0.17	0.20	0.49	0.23	0.26	0.45	0.63	0.81	0.92	0.48	0.49	0.23	0.24	0.63	0.13	0.45	0.17	0.67	0.13	0.69	0.17	0.56	1.00	0.45	0.58	0.24	0.83
5741 (PTH)	0.70	0.44	0.48	0.73	0.66	0.50	0.76	0.76	0.63	0.58	0.74	0.46	0.49	0.23	0.47	0.63	0.40	0.16	0.50	0.25	1.00	0.39	0.14	0.37	0.46	0.53	0.76	0.46	0.49	0.47	0.18	0.18	0.47	0.53	0.55	0.44	0.12	0.54	0.14	0.12	0.12	0.26	0.14	0.13	0.30	0.54	0.16	0.54	0.23
111 (ADCY5)	0.41	0.32	0.37	0.53	0.44	0.39	0.50	0.48	0.53	0.37	0.46	0.33	0.38	0.17	0.35	0.43	0.31	0.11	0.40	0.19	0.39	1.00	1.00	0.81	0.37	0.77	0.51	0.37	0.37	0.35	0.08	0.13	0.41	0.74	0.50	0.32	0.63	0.46	1.00	0.09	0.63	0.20	1.00	0.10	0.18	0.46	0.07	0.53	0.18
113 (ADCY7)	0.14	0.17	0.17	0.17	0.14	0.17	0.17	0.17	0.17	0.21	0.14	0.17	0.17	0.12	0.17	0.19	0.14	0.12	0.17	0.17	0.14	1.00	1.00	1.00	0.17	1.00	0.17	0.17	0.17	0.17	0.08	0.14	0.17	1.00	0.19	0.17	1.00	0.17	1.00	0.09	1.00	0.14	1.00	0.10	0.17	0.17	0.07	0.19	0.12
108 (ADCY2)	0.38	0.32	0.36	0.49	0.39	0.38	0.46	0.46	0.48	0.35	0.41	0.34	0.37	0.18	0.35	0.41	0.36	0.11	0.42	0.20	0.37	0.81	1.00	1.00	0.36	0.66	0.47	0.36	0.36	0.35	0.08	0.13	0.40	0.65	0.46	0.32	0.48	0.43	1.00	0.08	0.48	0.21	1.00	0.09	0.18	0.43	0.07	0.48	0.19
154 (ADRB2)	0.45	0.59	0.61	0.57	0.41	0.61	0.52	0.54	0.54	0.39	0.44	0.57	0.63	0.51	0.65	0.51	0.54	0.38	0.61	0.49	0.46	0.37	0.17	0.36	1.00	0.46	0.54	0.86	0.66	0.64	0.61	0.34	0.79	0.48	0.48	0.54	0.13	0.55	0.17	0.29	0.13	0.47	0.17	0.36	0.48	0.55	0.52	0.47	0.47
196883 (ADCY4)	0.56	0.40	0.46	0.70	0.56	0.48	0.66	0.65	0.69	0.47	0.60	0.42	0.48	0.21	0.44	0.58	0.39	0.14	0.51	0.23	0.53	0.77	1.00	0.66	0.46	1.00	0.68	0.45	0.47	0.44	0.12	0.16	0.46	0.98	0.62	0.40	0.63	0.56	1.00	0.10	0.63	0.25	1.00	0.12	0.26	0.56	0.11	0.60	0.22
1392 (CRH)	0.83	0.51	0.57	0.93	0.84	0.60	0.94	0.89	0.78	0.73	0.92	0.54	0.59	0.25	0.55	0.69	0.48	0.14	0.61	0.26	0.76	0.51	0.17	0.47	0.54	0.68	1.00	0.54	0.57	0.55	0.12	0.16	0.54	0.67	0.71	0.51	0.14	0.69	0.17	0.10	0.14	0.29	0.17	0.11	0.26	0.69	0.11	0.69	0.26
155 (ADRB3)	0.45	0.63	0.61	0.57	0.41	0.63	0.52	0.53	0.53	0.37	0.44	0.58	0.65	0.55	0.67	0.50	0.60	0.49	0.66	0.45	0.46	0.37	0.17	0.36	0.86	0.45	0.54	1.00	0.65	0.66	0.61	0.41	0.86	0.46	0.47	0.55	0.12	0.59	0.17	0.39	0.12	0.52	0.17	0.48	0.26	0.59	0.52	0.46	0.49
7253 (TSHR)	0.49	0.73	0.71	0.60	0.44	0.75	0.55	0.56	0.56	0.39	0.48	0.74	0.79	0.70	0.81	0.52	0.62	0.66	0.68	0.63	0.49	0.37	0.17	0.36	0.66	0.47	0.57	0.65	1.00	0.82	0.92	0.65	0.62	0.48	0.50	0.73	0.14	0.69	0.17	0.64	0.14	0.72	0.17	0.60	0.26	0.69	0.58	0.48	0.66
2740 (GLP1R)	0.47	0.81	0.86	0.57	0.41	0.86	0.52	0.54	0.52	0.37	0.46	0.84	0.95	0.88	0.97	0.50	0.62	0.64	0.69	0.81	0.47	0.35	0.17	0.35	0.64	0.44	0.55	0.66	0.82	1.00	0.92	0.57	0.63	0.45	0.46	0.77	0.13	0.68	0.17	0.69	0.13	0.75	0.17	0.63	0.26	0.68	0.66	0.45	0.87
387129 (NPSR1)	0.09	0.78	0.69	0.12	0.09	0.69	0.12	0.12	0.12	0.09	0.09	0.76	0.92	0.92	0.92	0.12	0.59	0.78	0.59	0.92	0.18	0.08	0.08	0.08	0.61	0.12	0.12	0.61	0.92	0.92	1.00	0.59	0.61	0.12	0.12	0.76	0.08	0.51	0.08	0.92	0.08	0.92	0.08	0.78	0.12	0.51	0.51	0.12	0.92
5032 (P2RY11)	0.13	0.50	0.51	0.16	0.14	0.56	0.16	0.15	0.17	0.13	0.14	0.45	0.51	0.62	0.58	0.14	0.49	0.83	0.45	0.48	0.18	0.13	0.14	0.13	0.34	0.16	0.16	0.41	0.65	0.57	0.59	1.00	0.35	0.15	0.16	0.52	0.12	0.45	0.14	0.61	0.12	0.55	0.14	0.70	0.20	0.45	0.55	0.16	0.56
153 (ADRB1)	0.47	0.61	0.59	0.56	0.43	0.60	0.51	0.54	0.53	0.40	0.47	0.56	0.62	0.48	0.64	0.53	0.56	0.41	0.63	0.49	0.47	0.41	0.17	0.40	0.79	0.46	0.54	0.86	0.62	0.63	0.61	0.35	1.00	0.47	0.48	0.54	0.12	0.57	0.17	0.32	0.12	0.47	0.17	0.39	0.82	0.57	0.52	0.47	0.43
112 (ADCY6)	0.55	0.42	0.48	0.69	0.55	0.50	0.65	0.65	0.68	0.47	0.58	0.44	0.49	0.21	0.46	0.58	0.40	0.13	0.52	0.23	0.53	0.74	1.00	0.65	0.48	0.98	0.67	0.46	0.48	0.45	0.12	0.15	0.47	1.00	0.62	0.42	0.54	0.57	1.00	0.10	0.54	0.25	1.00	0.11	0.26	0.57	0.11	0.60	0.22
54331 (GNG2)	0.58	0.43	0.49	0.73	0.60	0.52	0.69	0.68	0.73	0.48	0.63	0.45	0.51	0.22	0.47	0.73	0.42	0.14	0.54	0.24	0.55	0.50	0.19	0.46	0.48	0.62	0.71	0.47	0.50	0.46	0.12	0.16	0.48	0.62	1.00	0.43	0.17	0.61	0.19	0.10	0.17	0.26	0.19	0.12	0.26	0.61	0.11	0.92	0.24
10267 (RAMP1)	0.44	0.88	0.70	0.53	0.37	0.70	0.48	0.51	0.48	0.34	0.42	0.83	0.76	0.66	0.76	0.48	0.50	0.52	0.57	0.63	0.44	0.32	0.17	0.32	0.54	0.40	0.51	0.55	0.73	0.77	0.76	0.52	0.54	0.42	0.43	1.00	0.12	0.54	0.17	0.52	0.12	0.58	0.17	0.46	0.26	0.54	0.45	0.42	0.65
114 (ADCY8)	0.11	0.12	0.13	0.14	0.13	0.13	0.14	0.13	0.15	0.15	0.13	0.12	0.13	0.10	0.13	0.13	0.11	0.11	0.13	0.13	0.12	0.63	1.00	0.48	0.13	0.63	0.14	0.12	0.14	0.13	0.08	0.12	0.12	0.54	0.17	0.12	1.00	0.14	1.00	0.08	1.00	0.11	1.00	0.09	0.17	0.14	0.07	0.17	0.10
5734 (PTGER4)	0.57	0.60	0.61	0.72	0.58	0.66	0.67	0.66	0.71	0.45	0.62	0.59	0.69	0.56	0.70	0.57	0.57	0.51	0.66	0.45	0.54	0.46	0.17	0.43	0.55	0.56	0.69	0.59	0.69	0.68	0.51	0.45	0.57	0.57	0.61	0.54	0.14	1.00	0.17	0.45	0.14	0.53	0.17	0.52	0.26	0.90	1.00	0.59	0.51
115 (ADCY9)	0.14	0.17	0.17	0.17	0.14	0.17	0.17	0.17	0.17	0.21	0.14	0.17	0.17	0.12	0.17	0.19	0.14	0.12	0.17	0.17	0.14	1.00	1.00	1.00	0.17	1.00	0.17	0.17	0.17	0.17	0.08	0.14	0.17	1.00	0.19	0.17	1.00	0.17	1.00	0.09	1.00	0.14	1.00	0.10	0.17	0.17	0.07	0.19	0.12
53831 (GPR84)	0.08	0.56	0.44	0.10	0.09	0.50	0.10	0.09	0.11	0.08	0.09	0.62	0.65	0.77	0.66	0.08	0.45	0.73	0.40	0.67	0.12	0.09	0.09	0.08	0.29	0.10	0.10	0.39	0.64	0.69	0.92	0.61	0.32	0.10	0.10	0.52	0.08	0.45	0.09	1.00	0.08	0.73	0.09	0.78	0.12	0.45	0.58	0.10	0.75
107 (ADCY1)	0.11	0.12	0.13	0.14	0.13	0.13	0.14	0.13	0.15	0.15	0.13	0.12	0.13	0.10	0.13	0.13	0.11	0.11	0.13	0.13	0.12	0.63	1.00	0.48	0.13	0.63	0.14	0.12	0.14	0.13	0.08	0.12	0.12	0.54	0.17	0.12	1.00	0.14	1.00	0.08	1.00	0.11	1.00	0.09	0.17	0.14	0.07	0.17	0.10
3973 (LHCGR)	0.24	0.66	0.62	0.30	0.23	0.64	0.28	0.28	0.29	0.20	0.25	0.66	0.72	0.79	0.73	0.26	0.52	0.66	0.53	0.69	0.26	0.20	0.14	0.21	0.47	0.25	0.29	0.52	0.72	0.75	0.92	0.55	0.47	0.25	0.26	0.58	0.11	0.53	0.14	0.73	0.11	1.00	0.14	0.69	0.21	0.53	0.58	0.25	0.75
109 (ADCY3)	0.14	0.17	0.17	0.17	0.14	0.17	0.17	0.17	0.17	0.21	0.14	0.17	0.17	0.12	0.17	0.19	0.14	0.12	0.17	0.17	0.14	1.00	1.00	1.00	0.17	1.00	0.17	0.17	0.17	0.17	0.08	0.14	0.17	1.00	0.19	0.17	1.00	0.17	1.00	0.09	1.00	0.14	1.00	0.10	0.17	0.17	0.07	0.19	0.12
83551 (TAAR8)	0.09	0.58	0.48	0.12	0.11	0.55	0.11	0.11	0.12	0.09	0.11	0.53	0.60	0.78	0.65	0.10	0.51	0.84	0.46	0.56	0.13	0.10	0.10	0.09	0.36	0.12	0.11	0.48	0.60	0.63	0.78	0.70	0.39	0.11	0.12	0.46	0.09	0.52	0.10	0.78	0.09	0.69	0.10	1.00	0.14	0.52	0.70	0.12	0.69
5739 (PTGIR)	0.21	0.26	0.26	0.26	0.21	0.26	0.26	0.26	0.26	0.26	0.21	0.26	0.26	0.17	0.26	0.26	0.21	0.18	0.26	1.00	0.30	0.18	0.17	0.18	0.48	0.26	0.26	0.26	0.26	0.26	0.12	0.20	0.82	0.26	0.26	0.26	0.17	0.26	0.17	0.12	0.17	0.21	0.17	0.14	1.00	0.26	0.11	0.26	0.17
5729 (PTGDR)	0.57	0.60	0.61	0.72	0.58	0.66	0.67	0.66	0.71	0.45	0.62	0.59	0.69	0.56	0.70	0.57	0.57	0.51	0.66	0.45	0.54	0.46	0.17	0.43	0.55	0.56	0.69	0.59	0.69	0.68	0.51	0.45	0.57	0.57	0.61	0.54	0.14	0.90	0.17	0.45	0.14	0.53	0.17	0.52	0.26	1.00	0.80	0.59	0.51
5732 (PTGER2)	0.09	0.70	0.60	0.11	0.09	0.60	0.11	0.11	0.11	0.09	0.09	0.45	0.60	0.70	0.66	0.11	0.51	0.70	0.51	0.58	0.16	0.07	0.07	0.07	0.52	0.11	0.11	0.52	0.58	0.66	0.51	0.55	0.52	0.11	0.11	0.45	0.07	1.00	0.07	0.58	0.07	0.58	0.07	0.70	0.11	0.80	1.00	0.11	0.60
2784 (GNB3)	0.57	0.41	0.48	0.72	0.58	0.50	0.67	0.66	0.71	0.47	0.61	0.43	0.49	0.22	0.45	0.72	0.40	0.14	0.52	0.24	0.54	0.53	0.19	0.48	0.47	0.60	0.69	0.46	0.48	0.45	0.12	0.16	0.47	0.60	0.92	0.42	0.17	0.59	0.19	0.10	0.17	0.25	0.19	0.12	0.26	0.59	0.11	1.00	0.23
6344 (SCTR)	0.22	0.72	0.78	0.27	0.21	0.76	0.25	0.25	0.26	0.18	0.23	0.75	0.85	0.94	0.85	0.22	0.50	0.67	0.49	0.83	0.23	0.18	0.12	0.19	0.47	0.22	0.26	0.49	0.66	0.87	0.92	0.56	0.43	0.22	0.24	0.65	0.10	0.51	0.12	0.75	0.10	0.75	0.12	0.69	0.17	0.51	0.60	0.23	1.00

Association with High Altitude

Protein Official symbol	Source Organism	Tissue of Expression	Level of hypoxia	Altitude	Duration of experiment	Level of expression	Fold change	Experiment details	geographical location	ethnicity of the patients	Control group	Control (Fold change)	Reference (PMID)
ADORA2B	Mice	Blood	8% Oxygen	7600 m	24 hours	upregulated	14.2	RT-qPCR	Western US	C57BL/6 mice	3.9	7600m mice(8% oxygen with no Fenofibrate injections Vs Baseline normoxia mice (21% oxygen)	24183776
ADORA2B	Mice	Blood	8% Oxygen	7600 m	24 hours	upregulated	11.8	RT-qPCR	Western US	C57BL/6 mice	3.9	7600m mice(8% oxygen with Fenofibrate injections Vs Baseline normoxia mice (21% oxygen)	24183776
ADORA2B	Human	Blood	-	3500 m	24 hours	upregulated	2.5	RT-qPCR	The South Atlantic States, USA	Americans	1	Soldier exposed to high altitude compared to their low altitude profile	24183776
ADORA2B	Human	Blood	-	4000 m	24 hours	upregulated	4	RT-qPCR	The South Atlantic States, USA	Americans	1	Soldier exposed to high altitude compared to their low altitude profile	24183776
ADORA2B	Human	Blood	-	3000m	24 hours	upregulated	1.7	RT-qPCR	The South Atlantic States, USA	Americans	1	Soldier exposed to high altitude compared to their low altitude profile	24183776

Association with TF

TF	TF Entrez	Gene	Gene Entrez	Type	PMID	Database

Association with miRNA

miRTarBase ID	miRNA	Species (miRNA)	Protein Official Symbol	Human Entrez ID	Species (Target Gene)	Experiments	Support Type	References (PMID)
MIRT004499	hsa-miR-27b-3p	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT004499	hsa-miR-27b-3p	Homo sapiens	ADORA2B	136	Homo sapiens	qRT-PCR//Luciferase reporter assay	Functional MTI	20388705
MIRT035581	hsa-miR-128-3p	Homo sapiens	ADORA2B	136	Homo sapiens	Luciferase reporter assay//qRT-PCR//Western blot	Functional MTI	26478435
MIRT035581	hsa-miR-128-3p	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT076091	hsa-miR-452-5p	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT076092	hsa-miR-513a-5p	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT076119	hsa-miR-4676-3p	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT076103	hsa-miR-1208	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT076127	hsa-miR-892c-3p	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT076090	hsa-miR-377-3p	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT076088	hsa-miR-27a-3p	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT116050	hsa-miR-30d-3p	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT116052	hsa-miR-545-5p	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT116049	hsa-miR-30a-3p	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT116051	hsa-miR-30e-3p	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT482415	hsa-miR-5095	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23592263
MIRT482414	hsa-miR-7151-3p	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT482415	hsa-miR-5095	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT482420	hsa-miR-5003-3p	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT482418	hsa-miR-3934-5p	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT482413	hsa-miR-6807-5p	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT482414	hsa-miR-7151-3p	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23592263
MIRT482416	hsa-miR-6850-3p	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT482420	hsa-miR-5003-3p	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23592263
MIRT482422	hsa-miR-944	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT482417	hsa-miR-6872-3p	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23592263
MIRT482419	hsa-miR-6504-3p	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT482413	hsa-miR-6807-5p	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23592263
MIRT482418	hsa-miR-3934-5p	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23592263
MIRT482421	hsa-miR-552-3p	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23592263
MIRT482421	hsa-miR-552-3p	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT482417	hsa-miR-6872-3p	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT482422	hsa-miR-944	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23592263
MIRT482416	hsa-miR-6850-3p	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23592263
MIRT482419	hsa-miR-6504-3p	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23592263
MIRT559718	hsa-miR-222-5p	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT559721	hsa-miR-3681-3p	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT559719	hsa-miR-216b-3p	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT559720	hsa-miR-216a-3p	Homo sapiens	ADORA2B	136	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407

Gene Ontology

ID	GO ID	GO Term	GO Type
136	GO:0007190	activation of adenylate cyclase activity	GOTERM_BP_DIRECT
136	GO:0000187	activation of MAPK activity	GOTERM_BP_DIRECT
136	GO:0007588	excretion	GOTERM_BP_DIRECT
136	GO:0032722	positive regulation of chemokine production	GOTERM_BP_DIRECT
136	GO:0002882	positive regulation of chronic inflammatory response to non-antigenic stimulus	GOTERM_BP_DIRECT
136	GO:0001973	adenosine receptor signaling pathway	GOTERM_BP_DIRECT
136	GO:0032755	positive regulation of interleukin-6 production	GOTERM_BP_DIRECT
136	GO:0007186	G-protein coupled receptor signaling pathway	GOTERM_BP_DIRECT
136	GO:0060087	relaxation of vascular smooth muscle	GOTERM_BP_DIRECT
136	GO:0010575	positive regulation of vascular endothelial growth factor production	GOTERM_BP_DIRECT
136	GO:0005622	intracellular	GOTERM_CC_DIRECT
136	GO:0001609	beta-amyloid binding	GOTERM_MF_DIRECT
136	GO:0004930	transmembrane signaling receptor activity	GOTERM_MF_DIRECT
136	GO:0005886	plasma membrane	GOTERM_CC_DIRECT
136	GO:0005887	integral component of plasma membrane	GOTERM_CC_DIRECT
136	GO:0016021	integral component of membrane	GOTERM_CC_DIRECT
136	GO:0006968	cellular defense response	GOTERM_BP_DIRECT
136	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway	GOTERM_BP_DIRECT
136	GO:0007254	JNK cascade	GOTERM_BP_DIRECT
136	GO:0031668	cellular response to extracellular stimulus	GOTERM_BP_DIRECT
136	GO:0043306	positive regulation of mast cell degranulation	GOTERM_BP_DIRECT
136	GO:0031284	positive regulation of guanylate cyclase activity	GOTERM_BP_DIRECT
136	GO:0044267	cellular protein metabolic process	GOTERM_BP_DIRECT

Pathways

Human Entrez ID	KEGG ID	KEGG Term
136	hsa04020	Calcium signaling pathway
136	hsa04080	Neuroactive ligand-receptor interaction
136	hsa04015	Rap1 signaling pathway
136	hsa04270	Vascular smooth muscle contraction
136	hsa05034	Alcoholism

Association with Disease

Protein Official Symbol	Human Entrez ID	Disease Name	Disease Id	Disease Semantic Type	Semantic score	DSI	DPI	Disease Type
ADORA2B	136	Septicemia	C0036690	Disease or Syndrome	0.3	0.656	0.483	disease
ADORA2B	136	Sepsis	C0243026	Disease or Syndrome	0.3	0.656	0.483	disease
ADORA2B	136	Pyemia	C0034189	Pathologic Function	0.3	0.656	0.483	phenotype
ADORA2B	136	Neoplasm Metastasis	C0027627	Neoplastic Process	0.3	0.656	0.483	phenotype
ADORA2B	136	Reperfusion Injury	C0035126	Injury or Poisoning	0.3	0.656	0.483	disease
ADORA2B	136	Severe Sepsis	C1719672	Disease or Syndrome	0.3	0.656	0.483	disease

Association with Drug

Protein Official Symbol	Human Entrez ID	drug_claim_primary_name	drug_name	drug_chembl_id	interaction_types
ADORA2B	136	[125I]ABOPX	None	None	antagonist
ADORA2B	136	(R)-PIA	(R)-PIA	CHEMBL139000	agonist
ADORA2B	136	(S)-PIA	(S)-PIA	CHEMBL420705	agonist
ADORA2B	136	[3H]DPCPX	None	None	antagonist
ADORA2B	136	[3H]OSIP339391	CHEMBL485862	CHEMBL485862	antagonist
ADORA2B	136	[3H]MRS1754	CHEMBL273807	CHEMBL273807	antagonist
ADORA2B	136	[3H]ZM 241385	[3H]-ZM-241385	CHEMBL1628684	antagonist
ADORA2B	136	[3H]PSB603	CHEMBL483688	CHEMBL483688	antagonist
ADORA2B	136	2-HEXYNYL-NECA	CHEMBL410873	CHEMBL410873	agonist
ADORA2B	136	2-CHLOROADENOSINE	CHEMBL285819	CHEMBL285819	agonist
ADORA2B	136	3-ISOBUTYL-8-PYRROLIDINOXANTHINE	None	None	antagonist
ADORA2B	136	AB-NECA	None	None	agonist
ADORA2B	136	ADENOSINE	ADENOSINE	CHEMBL477	agonist
ADORA2B	136	ADENOSINE	ADENOSINE	CHEMBL477	agonist
ADORA2B	136	ALLOXAZINE	ALLOXAZINE	CHEMBL68500	antagonist
ADORA2B	136	AMINOPHYLLINE	AMINOPHYLLINE	CHEMBL1370561	antagonist
ADORA2B	136	AS95	CHEMBL431703	CHEMBL431703	antagonist
ADORA2B	136	AS74	CHEMBL32582	CHEMBL32582	antagonist
ADORA2B	136	AS96	CHEMBL2113342	CHEMBL2113342	antagonist
ADORA2B	136	AS70	None	None	antagonist
ADORA2B	136	AS94	CHEMBL284615	CHEMBL284615	antagonist
ADORA2B	136	AS16	CHEMBL285900	CHEMBL285900	antagonist
ADORA2B	136	AS100	None	None	antagonist
ADORA2B	136	AS101	CHLORFENSON	CHEMBL499017	antagonist
ADORA2B	136	AS99	None	None	antagonist
ADORA2B	136	ATL802	None	None	antagonist
ADORA2B	136	BAY 60-6583	None	None	agonist
ADORA2B	136	BIIB014	VIPADENANT	CHEMBL447664	None
ADORA2B	136	BINODENOSON	BINODENOSON	CHEMBL1950554	agonist
ADORA2B	136	BINODENOSON	BINODENOSON	CHEMBL1950554	None
ADORA2B	136	BVT.115959	BVT.115959	CHEMBL3545409	None
ADORA2B	136	CAFFEINE	CAFFEINE	CHEMBL113	None
ADORA2B	136	CAFFEINE	CAFFEINE	CHEMBL113	antagonist
ADORA2B	136	BW-A1433	CHEMBL16997	CHEMBL16997	antagonist
ADORA2B	136	CAFFEINE	CAFFEINE	CHEMBL113	antagonist
ADORA2B	136	CAFFEINE, CITRATED	CAFFEINE, CITRATED	CHEMBL1200569	antagonist
ADORA2B	136	CCPA	N6-CYCLOPENTYLADENOSINE	CHEMBL68738	agonist
ADORA2B	136	CGS 15943	CGS-15943	CHEMBL16687	antagonist
ADORA2B	136	CGS 21680	CGS-21680	CHEMBL331372	agonist
ADORA2B	136	CL-IB-MECA	CF102	CHEMBL431733	agonist
ADORA2B	136	CPX	None	None	antagonist
ADORA2B	136	CVT-6883	GS 6201	CHEMBL260933	None
ADORA2B	136	CVT-6883	GS 6201	CHEMBL260933	antagonist
ADORA2B	136	CYCLOPENTYLADENOSINE	N6-CYCLOPENTYLADENOSINE	CHEMBL68738	agonist
ADORA2B	136	DAX	BUPROPION	CHEMBL894	antagonist
ADORA2B	136	DERENOFYLLINE	Derenofylline	CHEMBL592435	antagonist
ADORA2B	136	DEPX	CHEMBL11348	CHEMBL11348	antagonist
ADORA2B	136	DPCPX	1,3-DIPROPYL-8-CYCLOPENTYLXANTHINE [DPCPX]	CHEMBL183	antagonist
ADORA2B	136	ENPROFYLLINE PARADOX	None	None	antagonist
ADORA2B	136	FK-453	FK453	CHEMBL440115	antagonist
ADORA2B	136	GS 6201	GS 6201	CHEMBL260933	antagonist
ADORA2B	136	HEMADO	CHEMBL260563	CHEMBL260563	agonist
ADORA2B	136	GS9667	None	None	agonist
ADORA2B	136	I-ABOPX	CHEMBL355370	CHEMBL355370	antagonist
ADORA2B	136	ISTRADEFYLLINE	ISTRADEFYLLINE	CHEMBL431770	antagonist
ADORA2B	136	ISTRADEFYLLINE	ISTRADEFYLLINE	CHEMBL431770	None
ADORA2B	136	KF26777	CHEMBL2181965	CHEMBL2181965	antagonist
ADORA2B	136	LAS101057	LAS101057	CHEMBL1672627	antagonist
ADORA2B	136	LAS38096	CHEMBL375293	CHEMBL375293	antagonist
ADORA2B	136	LUF5981	CHEMBL219160	CHEMBL219160	antagonist
ADORA2B	136	MRE 2029F20	None	None	antagonist
ADORA2B	136	MRS1191	CHEMBL89852	CHEMBL89852	antagonist
ADORA2B	136	MRS1220	CHEMBL88147	CHEMBL88147	antagonist
ADORA2B	136	MRS1523	CHEMBL111545	CHEMBL111545	antagonist
ADORA2B	136	MRS3558	CHEMBL175543	CHEMBL175543	agonist
ADORA2B	136	MRE 3008F20	CHEMBL302765	CHEMBL302765	antagonist
ADORA2B	136	MRS1754	CHEMBL273807	CHEMBL273807	antagonist
ADORA2B	136	MSX-2	None	None	antagonist
ADORA2B	136	N(6)-CYCLOHEXYLADENOSINE	GRAPIPRANT	CHEMBL3039498	agonist
ADORA2B	136	NECA	NECA	CHEMBL464859	agonist
ADORA2B	136	OSIP339391	CHEMBL485862	CHEMBL485862	antagonist
ADORA2B	136	OXTRIPHYLLINE	OXTRIPHYLLINE	CHEMBL1200434	antagonist
ADORA2B	136	PENTOXIFYLLINE	PENTOXIFYLLINE	CHEMBL628	antagonist
ADORA2B	136	PENTOXIFYLLINE	PENTOXIFYLLINE	CHEMBL628	antagonist
ADORA2B	136	PENTOXIFYLLINE	PENTOXIFYLLINE	CHEMBL628	None
ADORA2B	136	PICLIDENOSON	None	None	agonist
ADORA2B	136	PRELADENANT	PRELADENANT	CHEMBL240624	None
ADORA2B	136	PRELADENANT	PRELADENANT	CHEMBL240624	antagonist
ADORA2B	136	PSB1115	CHEMBL8565	CHEMBL8565	antagonist
ADORA2B	136	PSB36	None	None	antagonist
ADORA2B	136	PSB-0788	CHEMBL482436	CHEMBL482436	antagonist
ADORA2B	136	QAF805	QAF805	CHEMBL3545204	antagonist
ADORA2B	136	PSB603	None	None	antagonist
ADORA2B	136	REGADENOSON	REGADENOSON	CHEMBL317052	None
ADORA2B	136	REGADENOSON	REGADENOSON	CHEMBL317052	agonist
ADORA2B	136	ROLOFYLLINE	ROLOFYLLINE (CHEMBL2103819)	CHEMBL2103819	antagonist
ADORA2B	136	SCH 58261	IMISOPASEM MANGANESE	CHEMBL3544979	antagonist
ADORA2B	136	SCH442416	CHEMBL136689	CHEMBL136689	antagonist
ADORA2B	136	ST-1535	ST1535	CHEMBL197669	antagonist
ADORA2B	136	TCPA	CHEMBL1895774	CHEMBL1895774	agonist
ADORA2B	136	THEOPHYLLINE	THEOPHYLLINE	CHEMBL190	None
ADORA2B	136	THEOPHYLLINE	THEOPHYLLINE	CHEMBL190	None
ADORA2B	136	THEOPHYLLINE SODIUM GLYCINATE	THEOPHYLLINE SODIUM GLYCINATE	CHEMBL1200578	antagonist
ADORA2B	136	THEOPHYLLINE	THEOPHYLLINE	CHEMBL190	antagonist
ADORA2B	136	THEOPHYLLINE	THEOPHYLLINE	CHEMBL190	None
ADORA2B	136	THEOPHYLLINE	THEOPHYLLINE	CHEMBL190	antagonist
ADORA2B	136	TONAPOFYLLINE	TONAPOFYLLINE	CHEMBL414157	antagonist
ADORA2B	136	TOZADENANT	TOZADENANT	CHEMBL2105747	None
ADORA2B	136	VIPADENANT	VIPADENANT	CHEMBL447664	antagonist
ADORA2B	136	XCC	CHEMBL27041	CHEMBL27041	antagonist
ADORA2B	136	ZM-241385	ZM-241385	CHEMBL113142	antagonist
ADORA2B	136	XANTHINE	XANTHINE	CHEMBL1424	antagonist
ADORA2B	136	XANTHINE AMINE CONGENER	XANTHINE AMINE CONGENER	CHEMBL273094	antagonist