Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial
AltitudeomicsDB
Protein Official symbol |
ECH1 |
Aliases |
ECH1 |
Chromosomal Location |
19 |
Length |
328 |
Uniprot ID |
Q13011 |
EC number |
5.3.3.- |
Protein family Information(Pfam) |
PF00378; |
PDB id |
2VRE; |
InterPro ID |
IPR029045;IPR018376;IPR001753;IPR014748; |
dbSNP |
rs9419 rs2229259 |
AltitudeomicsDB
Protein 1 |
Protein 2 |
Combine Score |
LIN52 |
LIN37 |
0.999 |
LIN9 |
LIN37 |
0.999 |
LIN54 |
LIN37 |
0.999 |
LIN54 |
LIN9 |
0.999 |
LIN52 |
LIN9 |
0.999 |
RBBP4 |
LIN9 |
0.995 |
LIN52 |
LIN54 |
0.995 |
RBBP4 |
LIN37 |
0.991 |
RBBP4 |
LIN54 |
0.991 |
LIN52 |
RBBP4 |
0.985 |
DCAF7 |
DYRK1A |
0.983 |
LIN52 |
DYRK1A |
0.974 |
DYRK1A |
LIN54 |
0.945 |
DYRK1A |
LIN37 |
0.94 |
CCNL2 |
DYRK1A |
0.934 |
DYRK1A |
LIN9 |
0.932 |
DYRK1A |
RBBP4 |
0.93 |
DYRK1A |
RCAN1 |
0.909 |
Gene Ontology Semantic Similarity
Download Tab separated file
# |
5195 (PEX14) |
5193 (PEX12) |
7311 (UBA52) |
5828 (PEX2) |
7316 (UBC) |
7314 (UBB) |
7322 (UBE2D2) |
7321 (UBE2D1) |
5194 (PEX13) |
3295 (HSD17B4) |
10965 (ACOT2) |
54363 (HAO1) |
51179 (HAO2) |
7323 (UBE2D3) |
6342 (SCP2) |
51 (ACOX1) |
23600 (AMACR) |
51268 (PIPOX) |
8310 (ACOX3) |
8309 (ACOX2) |
122970 (ACOT4) |
55825 (PECR) |
219743 (TYSND1) |
390916 (NUDT19) |
847 (CAT) |
8443 (GNPAT) |
54677 (CROT) |
83752 (LONP2) |
570 (BAAT) |
1384 (CRAT) |
1962 (EHHADH) |
1891 (ECH1) |
5192 (PEX10) |
4843 (NOS2) |
189 (AGXT) |
8528 (DDO) |
196743 (PAOX) |
2053 (EPHX2) |
3417 (IDH1) |
3155 (HMGCL) |
26063 (DECR2) |
11001 (SLC27A2) |
10901 (DHRS4) |
373156 (GSTK1) |
26061 (HACL1) |
1610 (DAO) |
4358 (MPV17) |
3416 (IDE) |
283927 (NUDT7) |
6233 (RPS27A) |
10005 (ACOT8) |
5195 (PEX14)
|
1.00
|
0.62
|
1.00
|
1.00
|
0.66
|
1.00
|
0.58
|
0.58
|
1.00
|
0.48
|
0.58
|
0.47
|
0.54
|
0.58
|
0.54
|
0.67
|
0.59
|
0.64
|
0.58
|
0.49
|
0.53
|
0.59
|
0.44
|
0.58
|
0.53
|
0.53
|
0.58
|
0.71
|
0.50
|
0.58
|
0.62
|
0.76
|
1.00
|
0.51
|
0.58
|
0.68
|
0.54
|
0.51
|
0.54
|
0.53
|
0.54
|
0.50
|
0.44
|
0.65
|
0.66
|
0.66
|
0.48
|
0.61
|
0.53
|
0.62
|
0.52
|
5193 (PEX12)
|
0.62
|
1.00
|
1.00
|
1.00
|
0.62
|
1.00
|
0.84
|
0.84
|
1.00
|
0.43
|
0.49
|
0.41
|
0.46
|
0.84
|
0.51
|
0.57
|
0.52
|
0.58
|
0.49
|
0.44
|
0.45
|
0.50
|
0.42
|
0.49
|
0.49
|
0.47
|
0.51
|
0.68
|
0.53
|
0.51
|
0.57
|
0.69
|
1.00
|
0.47
|
0.59
|
0.61
|
0.46
|
0.52
|
0.56
|
0.63
|
0.46
|
0.45
|
0.40
|
0.64
|
0.63
|
0.60
|
0.48
|
0.66
|
0.46
|
0.56
|
0.47
|
7311 (UBA52)
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
0.82
|
0.82
|
0.82
|
0.82
|
1.00
|
1.00
|
0.82
|
0.82
|
1.00
|
0.82
|
0.82
|
0.82
|
0.82
|
0.69
|
0.82
|
0.82
|
0.82
|
0.82
|
1.00
|
1.00
|
0.82
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
0.82
|
0.82
|
0.82
|
0.82
|
0.82
|
0.82
|
0.82
|
1.00
|
1.00
|
1.00
|
0.48
|
1.00
|
0.82
|
1.00
|
1.00
|
5828 (PEX2)
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
0.82
|
0.82
|
0.82
|
0.82
|
1.00
|
1.00
|
0.82
|
0.82
|
1.00
|
0.82
|
0.82
|
0.82
|
0.82
|
0.69
|
0.82
|
0.82
|
0.82
|
0.82
|
1.00
|
1.00
|
0.82
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
0.82
|
0.82
|
0.82
|
0.82
|
0.82
|
0.82
|
0.82
|
1.00
|
1.00
|
1.00
|
0.48
|
1.00
|
0.82
|
1.00
|
1.00
|
7316 (UBC)
|
0.66
|
0.62
|
1.00
|
1.00
|
1.00
|
1.00
|
0.56
|
0.56
|
1.00
|
0.41
|
0.53
|
0.41
|
0.46
|
0.56
|
0.49
|
0.59
|
0.53
|
0.60
|
0.53
|
0.44
|
0.46
|
0.53
|
0.61
|
0.53
|
0.56
|
0.46
|
0.52
|
0.78
|
0.43
|
0.52
|
0.59
|
0.77
|
1.00
|
0.53
|
0.56
|
0.66
|
0.47
|
0.46
|
0.50
|
0.48
|
0.47
|
0.47
|
0.36
|
0.60
|
0.65
|
0.64
|
0.48
|
0.58
|
0.59
|
0.83
|
0.46
|
7314 (UBB)
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
0.82
|
0.82
|
0.82
|
0.82
|
1.00
|
1.00
|
0.82
|
0.82
|
1.00
|
0.82
|
0.82
|
0.82
|
0.82
|
0.69
|
0.82
|
0.82
|
0.82
|
0.82
|
1.00
|
1.00
|
0.82
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
0.82
|
0.82
|
0.82
|
0.82
|
0.82
|
0.82
|
0.82
|
1.00
|
1.00
|
1.00
|
0.48
|
1.00
|
0.82
|
1.00
|
1.00
|
7322 (UBE2D2)
|
0.58
|
0.84
|
1.00
|
1.00
|
0.56
|
1.00
|
1.00
|
1.00
|
1.00
|
0.40
|
0.44
|
0.37
|
0.41
|
1.00
|
0.48
|
0.54
|
0.48
|
0.53
|
0.44
|
0.41
|
0.40
|
0.46
|
0.38
|
0.44
|
0.47
|
0.44
|
0.47
|
0.65
|
0.52
|
0.47
|
0.53
|
0.63
|
1.00
|
0.43
|
0.58
|
0.56
|
0.42
|
0.43
|
0.47
|
0.44
|
0.42
|
0.42
|
0.36
|
0.62
|
0.59
|
0.57
|
0.48
|
0.53
|
0.43
|
0.49
|
0.43
|
7321 (UBE2D1)
|
0.58
|
0.84
|
1.00
|
1.00
|
0.56
|
1.00
|
1.00
|
1.00
|
1.00
|
0.40
|
0.44
|
0.37
|
0.41
|
1.00
|
0.48
|
0.54
|
0.48
|
0.53
|
0.44
|
0.41
|
0.40
|
0.46
|
0.38
|
0.44
|
0.47
|
0.44
|
0.47
|
0.65
|
0.52
|
0.47
|
0.53
|
0.63
|
1.00
|
0.43
|
0.58
|
0.56
|
0.42
|
0.43
|
0.47
|
0.44
|
0.42
|
0.42
|
0.36
|
0.62
|
0.59
|
0.57
|
0.48
|
0.53
|
0.43
|
0.49
|
0.43
|
5194 (PEX13)
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
0.82
|
0.82
|
0.82
|
0.82
|
1.00
|
1.00
|
0.82
|
0.82
|
1.00
|
0.82
|
0.82
|
0.82
|
0.82
|
0.69
|
0.82
|
0.82
|
0.82
|
0.82
|
1.00
|
1.00
|
0.82
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
0.82
|
0.82
|
0.82
|
0.82
|
0.82
|
0.82
|
0.82
|
1.00
|
1.00
|
1.00
|
0.48
|
1.00
|
0.82
|
1.00
|
1.00
|
3295 (HSD17B4)
|
0.48
|
0.43
|
0.82
|
0.82
|
0.41
|
0.82
|
0.40
|
0.40
|
0.82
|
1.00
|
0.42
|
0.48
|
0.53
|
0.40
|
0.39
|
0.51
|
0.46
|
0.51
|
0.46
|
0.54
|
0.39
|
0.48
|
0.29
|
0.42
|
0.55
|
0.38
|
0.39
|
0.55
|
0.40
|
0.39
|
0.85
|
0.50
|
0.82
|
0.46
|
0.50
|
0.50
|
0.47
|
0.47
|
0.64
|
0.52
|
0.47
|
0.39
|
0.62
|
0.51
|
0.58
|
0.53
|
0.38
|
0.50
|
0.42
|
0.37
|
0.39
|
10965 (ACOT2)
|
0.58
|
0.49
|
0.82
|
0.82
|
0.53
|
0.82
|
0.44
|
0.44
|
0.82
|
0.42
|
1.00
|
0.41
|
0.50
|
0.44
|
0.43
|
0.59
|
0.60
|
0.56
|
0.58
|
0.43
|
0.95
|
0.59
|
0.40
|
1.00
|
0.46
|
0.78
|
0.56
|
0.70
|
0.68
|
0.56
|
0.52
|
0.74
|
0.82
|
0.40
|
0.48
|
0.60
|
0.50
|
0.54
|
0.49
|
0.46
|
0.50
|
0.44
|
0.38
|
0.57
|
0.58
|
0.56
|
0.38
|
0.51
|
0.73
|
0.46
|
0.91
|
54363 (HAO1)
|
0.47
|
0.41
|
0.82
|
0.82
|
0.41
|
0.82
|
0.37
|
0.37
|
0.82
|
0.48
|
0.41
|
1.00
|
0.78
|
0.37
|
0.45
|
0.52
|
0.44
|
0.52
|
0.47
|
0.57
|
0.38
|
0.50
|
0.27
|
0.41
|
0.56
|
0.36
|
0.38
|
0.54
|
0.38
|
0.38
|
0.54
|
0.50
|
0.82
|
0.60
|
0.49
|
0.52
|
0.48
|
0.39
|
0.56
|
0.40
|
0.48
|
0.38
|
0.53
|
0.50
|
0.57
|
0.61
|
0.38
|
0.48
|
0.41
|
0.37
|
0.37
|
51179 (HAO2)
|
0.54
|
0.46
|
0.82
|
0.82
|
0.46
|
0.82
|
0.41
|
0.41
|
0.82
|
0.53
|
0.50
|
0.78
|
1.00
|
0.41
|
0.41
|
0.60
|
0.54
|
0.59
|
0.57
|
0.50
|
0.45
|
0.59
|
0.31
|
0.50
|
0.52
|
0.43
|
0.47
|
0.61
|
0.41
|
0.47
|
0.59
|
0.62
|
0.82
|
0.43
|
0.46
|
0.58
|
0.55
|
0.42
|
0.61
|
0.44
|
0.55
|
0.43
|
0.59
|
0.57
|
0.55
|
0.57
|
0.38
|
0.47
|
0.45
|
0.41
|
0.40
|
7323 (UBE2D3)
|
0.58
|
0.84
|
1.00
|
1.00
|
0.56
|
1.00
|
1.00
|
1.00
|
1.00
|
0.40
|
0.44
|
0.37
|
0.41
|
1.00
|
0.48
|
0.54
|
0.48
|
0.53
|
0.44
|
0.41
|
0.40
|
0.46
|
0.38
|
0.44
|
0.47
|
0.44
|
0.47
|
0.65
|
0.52
|
0.47
|
0.53
|
0.63
|
1.00
|
0.43
|
0.58
|
0.56
|
0.42
|
0.43
|
0.47
|
0.44
|
0.42
|
0.42
|
0.36
|
0.62
|
0.59
|
0.57
|
0.48
|
0.53
|
0.43
|
0.49
|
0.43
|
6342 (SCP2)
|
0.54
|
0.51
|
1.00
|
1.00
|
0.49
|
1.00
|
0.48
|
0.48
|
1.00
|
0.39
|
0.43
|
0.45
|
0.41
|
0.48
|
1.00
|
0.48
|
0.44
|
0.49
|
0.43
|
0.48
|
0.40
|
0.43
|
0.32
|
0.43
|
0.48
|
0.46
|
0.49
|
0.57
|
0.54
|
0.49
|
0.50
|
0.55
|
1.00
|
0.53
|
0.60
|
0.55
|
0.41
|
0.43
|
0.45
|
0.45
|
0.41
|
0.41
|
0.37
|
0.53
|
0.61
|
0.58
|
0.48
|
0.51
|
0.43
|
0.45
|
0.43
|
51 (ACOX1)
|
0.67
|
0.57
|
0.82
|
0.82
|
0.59
|
0.82
|
0.54
|
0.54
|
0.82
|
0.51
|
0.59
|
0.52
|
0.60
|
0.54
|
0.48
|
1.00
|
0.62
|
0.67
|
0.83
|
0.72
|
0.53
|
0.71
|
0.41
|
0.59
|
0.54
|
0.52
|
0.58
|
0.68
|
0.48
|
0.58
|
0.61
|
0.75
|
0.82
|
0.48
|
0.53
|
0.67
|
0.61
|
0.48
|
0.56
|
0.50
|
0.68
|
0.49
|
0.53
|
0.65
|
0.62
|
0.63
|
0.38
|
0.54
|
0.50
|
0.54
|
0.49
|
23600 (AMACR)
|
0.59
|
0.52
|
0.82
|
0.82
|
0.53
|
0.82
|
0.48
|
0.48
|
0.82
|
0.46
|
0.60
|
0.44
|
0.54
|
0.48
|
0.44
|
0.62
|
1.00
|
0.59
|
0.60
|
0.46
|
0.52
|
0.62
|
0.37
|
0.60
|
0.48
|
0.51
|
0.58
|
0.67
|
0.45
|
0.58
|
0.55
|
0.75
|
0.82
|
0.42
|
0.50
|
0.61
|
0.54
|
0.46
|
0.51
|
0.48
|
0.54
|
0.48
|
0.43
|
0.60
|
0.60
|
0.58
|
0.38
|
0.50
|
0.49
|
0.46
|
0.45
|
51268 (PIPOX)
|
0.64
|
0.58
|
1.00
|
1.00
|
0.60
|
1.00
|
0.53
|
0.53
|
1.00
|
0.51
|
0.56
|
0.52
|
0.59
|
0.53
|
0.49
|
0.67
|
0.59
|
1.00
|
0.62
|
0.55
|
0.50
|
0.64
|
0.40
|
0.56
|
0.58
|
0.49
|
0.53
|
0.71
|
0.48
|
0.53
|
0.62
|
0.72
|
1.00
|
0.51
|
0.55
|
0.67
|
0.82
|
0.49
|
0.60
|
0.51
|
0.60
|
0.48
|
0.53
|
0.65
|
0.65
|
0.66
|
0.48
|
0.57
|
0.51
|
0.54
|
0.48
|
8310 (ACOX3)
|
0.58
|
0.49
|
0.82
|
0.82
|
0.53
|
0.82
|
0.44
|
0.44
|
0.82
|
0.46
|
0.58
|
0.47
|
0.57
|
0.44
|
0.43
|
0.83
|
0.60
|
0.62
|
1.00
|
0.74
|
0.49
|
0.72
|
0.35
|
0.58
|
0.51
|
0.48
|
0.56
|
0.65
|
0.41
|
0.56
|
0.55
|
0.74
|
0.82
|
0.43
|
0.48
|
0.63
|
0.58
|
0.44
|
0.54
|
0.46
|
0.67
|
0.44
|
0.48
|
0.60
|
0.58
|
0.59
|
0.38
|
0.50
|
0.46
|
0.46
|
0.41
|
8309 (ACOX2)
|
0.49
|
0.44
|
0.82
|
0.82
|
0.44
|
0.82
|
0.41
|
0.41
|
0.82
|
0.54
|
0.43
|
0.57
|
0.50
|
0.41
|
0.48
|
0.72
|
0.46
|
0.55
|
0.74
|
1.00
|
0.40
|
0.57
|
0.30
|
0.43
|
0.66
|
0.39
|
0.41
|
0.55
|
0.42
|
0.41
|
0.52
|
0.52
|
0.82
|
0.68
|
0.58
|
0.54
|
0.50
|
0.48
|
0.59
|
0.50
|
0.56
|
0.41
|
0.49
|
0.53
|
0.61
|
0.67
|
0.38
|
0.54
|
0.44
|
0.40
|
0.41
|
122970 (ACOT4)
|
0.53
|
0.45
|
0.82
|
0.82
|
0.46
|
0.82
|
0.40
|
0.40
|
0.82
|
0.39
|
0.95
|
0.38
|
0.45
|
0.40
|
0.40
|
0.53
|
0.52
|
0.50
|
0.49
|
0.40
|
1.00
|
0.50
|
0.36
|
0.95
|
0.44
|
0.76
|
0.47
|
0.66
|
0.68
|
0.47
|
0.48
|
0.62
|
0.82
|
0.39
|
0.45
|
0.53
|
0.45
|
0.53
|
0.46
|
0.43
|
0.45
|
0.41
|
0.36
|
0.52
|
0.54
|
0.52
|
0.38
|
0.49
|
0.75
|
0.40
|
0.91
|
55825 (PECR)
|
0.59
|
0.50
|
0.82
|
0.82
|
0.53
|
0.82
|
0.46
|
0.46
|
0.82
|
0.48
|
0.59
|
0.50
|
0.59
|
0.46
|
0.43
|
0.71
|
0.62
|
0.64
|
0.72
|
0.57
|
0.50
|
1.00
|
0.36
|
0.59
|
0.52
|
0.49
|
0.57
|
0.66
|
0.42
|
0.57
|
0.57
|
0.74
|
0.82
|
0.44
|
0.49
|
0.64
|
0.60
|
0.45
|
0.55
|
0.47
|
0.95
|
0.46
|
0.51
|
0.62
|
0.59
|
0.60
|
0.38
|
0.50
|
0.47
|
0.46
|
0.43
|
219743 (TYSND1)
|
0.44
|
0.42
|
0.69
|
0.69
|
0.61
|
0.69
|
0.38
|
0.38
|
0.69
|
0.29
|
0.40
|
0.27
|
0.31
|
0.38
|
0.32
|
0.41
|
0.37
|
0.40
|
0.35
|
0.30
|
0.36
|
0.36
|
1.00
|
0.40
|
0.39
|
0.33
|
0.33
|
0.74
|
0.33
|
0.33
|
0.45
|
0.51
|
0.69
|
0.31
|
0.37
|
0.43
|
0.32
|
0.36
|
0.34
|
0.32
|
0.32
|
0.38
|
0.26
|
0.41
|
0.44
|
0.42
|
0.32
|
0.46
|
0.35
|
0.39
|
0.37
|
390916 (NUDT19)
|
0.58
|
0.49
|
0.82
|
0.82
|
0.53
|
0.82
|
0.44
|
0.44
|
0.82
|
0.42
|
1.00
|
0.41
|
0.50
|
0.44
|
0.43
|
0.59
|
0.60
|
0.56
|
0.58
|
0.43
|
0.95
|
0.59
|
0.40
|
1.00
|
0.46
|
0.78
|
0.56
|
0.70
|
0.68
|
0.56
|
0.52
|
0.74
|
0.82
|
0.40
|
0.48
|
0.60
|
0.50
|
0.54
|
0.49
|
0.46
|
0.50
|
0.44
|
0.38
|
0.57
|
0.58
|
0.56
|
0.38
|
0.51
|
0.73
|
0.46
|
0.91
|
847 (CAT)
|
0.53
|
0.49
|
0.82
|
0.82
|
0.56
|
0.82
|
0.47
|
0.47
|
0.82
|
0.55
|
0.46
|
0.56
|
0.52
|
0.47
|
0.48
|
0.54
|
0.48
|
0.58
|
0.51
|
0.66
|
0.44
|
0.52
|
0.39
|
0.46
|
1.00
|
0.43
|
0.45
|
0.64
|
0.47
|
0.45
|
0.59
|
0.56
|
0.82
|
0.74
|
0.58
|
0.58
|
0.52
|
0.51
|
0.59
|
0.51
|
0.52
|
0.49
|
0.52
|
0.66
|
0.61
|
0.65
|
0.64
|
0.55
|
0.53
|
0.51
|
0.46
|
8443 (GNPAT)
|
0.53
|
0.47
|
0.82
|
0.82
|
0.46
|
0.82
|
0.44
|
0.44
|
0.82
|
0.38
|
0.78
|
0.36
|
0.43
|
0.44
|
0.46
|
0.52
|
0.51
|
0.49
|
0.48
|
0.39
|
0.76
|
0.49
|
0.33
|
0.78
|
0.43
|
1.00
|
0.60
|
0.63
|
0.72
|
0.71
|
0.47
|
0.61
|
0.82
|
0.38
|
0.48
|
0.52
|
0.43
|
0.48
|
0.45
|
0.42
|
0.43
|
0.40
|
0.35
|
0.53
|
0.53
|
0.51
|
0.38
|
0.48
|
0.63
|
0.40
|
0.80
|
54677 (CROT)
|
0.58
|
0.51
|
0.82
|
0.82
|
0.52
|
0.82
|
0.47
|
0.47
|
0.82
|
0.39
|
0.56
|
0.38
|
0.47
|
0.47
|
0.49
|
0.58
|
0.58
|
0.53
|
0.56
|
0.41
|
0.47
|
0.57
|
0.33
|
0.56
|
0.45
|
0.60
|
1.00
|
0.63
|
0.50
|
0.78
|
0.50
|
0.73
|
0.82
|
0.39
|
0.49
|
0.58
|
0.48
|
0.42
|
0.47
|
0.45
|
0.48
|
0.41
|
0.35
|
0.58
|
0.57
|
0.55
|
0.38
|
0.49
|
0.44
|
0.45
|
0.39
|
83752 (LONP2)
|
0.71
|
0.68
|
1.00
|
1.00
|
0.78
|
1.00
|
0.65
|
0.65
|
1.00
|
0.55
|
0.70
|
0.54
|
0.61
|
0.65
|
0.57
|
0.68
|
0.67
|
0.71
|
0.65
|
0.55
|
0.66
|
0.66
|
0.74
|
0.70
|
0.64
|
0.63
|
0.63
|
1.00
|
0.61
|
0.63
|
0.73
|
0.82
|
1.00
|
0.54
|
0.63
|
0.73
|
0.61
|
0.62
|
0.60
|
0.57
|
0.61
|
0.64
|
0.53
|
0.72
|
0.72
|
0.70
|
0.48
|
0.68
|
0.62
|
0.65
|
0.68
|
570 (BAAT)
|
0.50
|
0.53
|
1.00
|
1.00
|
0.43
|
1.00
|
0.52
|
0.52
|
1.00
|
0.40
|
0.68
|
0.38
|
0.41
|
0.52
|
0.54
|
0.48
|
0.45
|
0.48
|
0.41
|
0.42
|
0.68
|
0.42
|
0.33
|
0.68
|
0.47
|
0.72
|
0.50
|
0.61
|
1.00
|
0.50
|
0.49
|
0.49
|
1.00
|
0.42
|
0.56
|
0.48
|
0.41
|
0.48
|
0.46
|
0.42
|
0.41
|
0.42
|
0.40
|
0.56
|
0.55
|
0.50
|
0.48
|
0.49
|
0.63
|
0.40
|
0.76
|
1384 (CRAT)
|
0.58
|
0.51
|
0.82
|
0.82
|
0.52
|
0.82
|
0.47
|
0.47
|
0.82
|
0.39
|
0.56
|
0.38
|
0.47
|
0.47
|
0.49
|
0.58
|
0.58
|
0.53
|
0.56
|
0.41
|
0.47
|
0.57
|
0.33
|
0.56
|
0.45
|
0.71
|
0.78
|
0.63
|
0.50
|
1.00
|
0.50
|
0.73
|
0.82
|
0.39
|
0.49
|
0.58
|
0.48
|
0.42
|
0.47
|
0.45
|
0.48
|
0.41
|
0.35
|
0.58
|
0.57
|
0.55
|
0.38
|
0.49
|
0.44
|
0.45
|
0.39
|
1962 (EHHADH)
|
0.62
|
0.57
|
1.00
|
1.00
|
0.59
|
1.00
|
0.53
|
0.53
|
1.00
|
0.85
|
0.52
|
0.54
|
0.59
|
0.53
|
0.50
|
0.61
|
0.55
|
0.62
|
0.55
|
0.52
|
0.48
|
0.57
|
0.45
|
0.52
|
0.59
|
0.47
|
0.50
|
0.73
|
0.49
|
0.50
|
1.00
|
0.66
|
1.00
|
0.50
|
0.55
|
0.63
|
0.54
|
0.48
|
0.62
|
0.53
|
0.54
|
0.52
|
0.65
|
0.62
|
0.68
|
0.63
|
0.48
|
0.56
|
0.50
|
0.53
|
0.48
|
1891 (ECH1)
|
0.76
|
0.69
|
1.00
|
1.00
|
0.77
|
1.00
|
0.63
|
0.63
|
1.00
|
0.50
|
0.74
|
0.50
|
0.62
|
0.63
|
0.55
|
0.75
|
0.75
|
0.72
|
0.74
|
0.52
|
0.62
|
0.74
|
0.51
|
0.74
|
0.56
|
0.61
|
0.73
|
0.82
|
0.49
|
0.73
|
0.66
|
1.00
|
1.00
|
0.51
|
0.59
|
0.79
|
0.63
|
0.54
|
0.60
|
0.58
|
0.63
|
0.53
|
0.45
|
0.72
|
0.73
|
0.72
|
0.48
|
0.64
|
0.56
|
0.69
|
0.52
|
5192 (PEX10)
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
0.82
|
0.82
|
0.82
|
0.82
|
1.00
|
1.00
|
0.82
|
0.82
|
1.00
|
0.82
|
0.82
|
0.82
|
0.82
|
0.69
|
0.82
|
0.82
|
0.82
|
0.82
|
1.00
|
1.00
|
0.82
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
1.00
|
0.82
|
0.82
|
0.82
|
0.82
|
0.82
|
0.82
|
0.82
|
1.00
|
1.00
|
1.00
|
0.48
|
1.00
|
0.82
|
1.00
|
1.00
|
4843 (NOS2)
|
0.51
|
0.47
|
1.00
|
1.00
|
0.53
|
1.00
|
0.43
|
0.43
|
1.00
|
0.46
|
0.40
|
0.60
|
0.43
|
0.43
|
0.53
|
0.48
|
0.42
|
0.51
|
0.43
|
0.68
|
0.39
|
0.44
|
0.31
|
0.40
|
0.74
|
0.38
|
0.39
|
0.54
|
0.42
|
0.39
|
0.50
|
0.51
|
1.00
|
1.00
|
0.65
|
0.56
|
0.43
|
0.48
|
0.54
|
0.50
|
0.43
|
0.39
|
0.44
|
0.50
|
0.64
|
0.69
|
0.48
|
0.59
|
0.46
|
0.50
|
0.42
|
189 (AGXT)
|
0.58
|
0.59
|
1.00
|
1.00
|
0.56
|
1.00
|
0.58
|
0.58
|
1.00
|
0.50
|
0.48
|
0.49
|
0.46
|
0.58
|
0.60
|
0.53
|
0.50
|
0.55
|
0.48
|
0.58
|
0.45
|
0.49
|
0.37
|
0.48
|
0.58
|
0.48
|
0.49
|
0.63
|
0.56
|
0.49
|
0.55
|
0.59
|
1.00
|
0.65
|
1.00
|
0.58
|
0.47
|
0.52
|
0.56
|
0.54
|
0.47
|
0.46
|
0.43
|
0.61
|
0.66
|
0.63
|
0.48
|
0.60
|
0.49
|
0.52
|
0.48
|
8528 (DDO)
|
0.68
|
0.61
|
1.00
|
1.00
|
0.66
|
1.00
|
0.56
|
0.56
|
1.00
|
0.50
|
0.60
|
0.52
|
0.58
|
0.56
|
0.55
|
0.67
|
0.61
|
0.67
|
0.63
|
0.54
|
0.53
|
0.64
|
0.43
|
0.60
|
0.58
|
0.52
|
0.58
|
0.73
|
0.48
|
0.58
|
0.63
|
0.79
|
1.00
|
0.56
|
0.58
|
1.00
|
0.59
|
0.51
|
0.58
|
0.53
|
0.59
|
0.49
|
0.49
|
0.66
|
0.76
|
0.88
|
0.48
|
0.60
|
0.51
|
0.59
|
0.50
|
196743 (PAOX)
|
0.54
|
0.46
|
0.82
|
0.82
|
0.47
|
0.82
|
0.42
|
0.42
|
0.82
|
0.47
|
0.50
|
0.48
|
0.55
|
0.42
|
0.41
|
0.61
|
0.54
|
0.82
|
0.58
|
0.50
|
0.45
|
0.60
|
0.32
|
0.50
|
0.52
|
0.43
|
0.48
|
0.61
|
0.41
|
0.48
|
0.54
|
0.63
|
0.82
|
0.43
|
0.47
|
0.59
|
1.00
|
0.42
|
0.54
|
0.44
|
0.56
|
0.43
|
0.50
|
0.58
|
0.56
|
0.57
|
0.38
|
0.47
|
0.45
|
0.41
|
0.41
|
2053 (EPHX2)
|
0.51
|
0.52
|
0.82
|
0.82
|
0.46
|
0.82
|
0.43
|
0.43
|
0.82
|
0.47
|
0.54
|
0.39
|
0.42
|
0.43
|
0.43
|
0.48
|
0.46
|
0.49
|
0.44
|
0.48
|
0.53
|
0.45
|
0.36
|
0.54
|
0.51
|
0.48
|
0.42
|
0.62
|
0.48
|
0.42
|
0.48
|
0.54
|
0.82
|
0.48
|
0.52
|
0.51
|
0.42
|
1.00
|
0.63
|
0.67
|
0.42
|
0.41
|
0.38
|
0.50
|
0.56
|
0.53
|
0.48
|
0.58
|
0.53
|
0.43
|
0.56
|
3417 (IDH1)
|
0.54
|
0.56
|
0.82
|
0.82
|
0.50
|
0.82
|
0.47
|
0.47
|
0.82
|
0.64
|
0.49
|
0.56
|
0.61
|
0.47
|
0.45
|
0.56
|
0.51
|
0.60
|
0.54
|
0.59
|
0.46
|
0.55
|
0.34
|
0.49
|
0.59
|
0.45
|
0.47
|
0.60
|
0.46
|
0.47
|
0.62
|
0.60
|
0.82
|
0.54
|
0.56
|
0.58
|
0.54
|
0.63
|
1.00
|
0.72
|
0.54
|
0.45
|
0.62
|
0.58
|
0.59
|
0.60
|
0.38
|
0.59
|
0.46
|
0.46
|
0.45
|
3155 (HMGCL)
|
0.53
|
0.63
|
0.82
|
0.82
|
0.48
|
0.82
|
0.44
|
0.44
|
0.82
|
0.52
|
0.46
|
0.40
|
0.44
|
0.44
|
0.45
|
0.50
|
0.48
|
0.51
|
0.46
|
0.50
|
0.43
|
0.47
|
0.32
|
0.46
|
0.51
|
0.42
|
0.45
|
0.57
|
0.42
|
0.45
|
0.53
|
0.58
|
0.82
|
0.50
|
0.54
|
0.53
|
0.44
|
0.67
|
0.72
|
1.00
|
0.44
|
0.42
|
0.38
|
0.52
|
0.64
|
0.54
|
0.38
|
0.64
|
0.42
|
0.44
|
0.43
|
26063 (DECR2)
|
0.54
|
0.46
|
0.82
|
0.82
|
0.47
|
0.82
|
0.42
|
0.42
|
0.82
|
0.47
|
0.50
|
0.48
|
0.55
|
0.42
|
0.41
|
0.68
|
0.54
|
0.60
|
0.67
|
0.56
|
0.45
|
0.95
|
0.32
|
0.50
|
0.52
|
0.43
|
0.48
|
0.61
|
0.41
|
0.48
|
0.54
|
0.63
|
0.82
|
0.43
|
0.47
|
0.59
|
0.56
|
0.42
|
0.54
|
0.44
|
1.00
|
0.43
|
0.50
|
0.58
|
0.56
|
0.57
|
0.38
|
0.47
|
0.45
|
0.41
|
0.41
|
11001 (SLC27A2)
|
0.50
|
0.45
|
0.82
|
0.82
|
0.47
|
0.82
|
0.42
|
0.42
|
0.82
|
0.39
|
0.44
|
0.38
|
0.43
|
0.42
|
0.41
|
0.49
|
0.48
|
0.48
|
0.44
|
0.41
|
0.41
|
0.46
|
0.38
|
0.44
|
0.49
|
0.40
|
0.41
|
0.64
|
0.42
|
0.41
|
0.52
|
0.53
|
0.82
|
0.39
|
0.46
|
0.49
|
0.43
|
0.41
|
0.45
|
0.42
|
0.43
|
1.00
|
0.38
|
0.50
|
0.53
|
0.50
|
0.38
|
0.46
|
0.44
|
0.40
|
0.41
|
10901 (DHRS4)
|
0.44
|
0.40
|
0.82
|
0.82
|
0.36
|
0.82
|
0.36
|
0.36
|
0.82
|
0.62
|
0.38
|
0.53
|
0.59
|
0.36
|
0.37
|
0.53
|
0.43
|
0.53
|
0.48
|
0.49
|
0.36
|
0.51
|
0.26
|
0.38
|
0.52
|
0.35
|
0.35
|
0.53
|
0.40
|
0.35
|
0.65
|
0.45
|
0.82
|
0.44
|
0.43
|
0.49
|
0.50
|
0.38
|
0.62
|
0.38
|
0.50
|
0.38
|
1.00
|
0.51
|
0.49
|
0.52
|
0.38
|
0.42
|
0.41
|
0.33
|
0.37
|
373156 (GSTK1)
|
0.65
|
0.64
|
1.00
|
1.00
|
0.60
|
1.00
|
0.62
|
0.62
|
1.00
|
0.51
|
0.57
|
0.50
|
0.57
|
0.62
|
0.53
|
0.65
|
0.60
|
0.65
|
0.60
|
0.53
|
0.52
|
0.62
|
0.41
|
0.57
|
0.66
|
0.53
|
0.58
|
0.72
|
0.56
|
0.58
|
0.62
|
0.72
|
1.00
|
0.50
|
0.61
|
0.66
|
0.58
|
0.50
|
0.58
|
0.52
|
0.58
|
0.50
|
0.51
|
1.00
|
0.66
|
0.65
|
0.48
|
0.57
|
0.52
|
0.54
|
0.50
|
26061 (HACL1)
|
0.66
|
0.63
|
1.00
|
1.00
|
0.65
|
1.00
|
0.59
|
0.59
|
1.00
|
0.58
|
0.58
|
0.57
|
0.55
|
0.59
|
0.61
|
0.62
|
0.60
|
0.65
|
0.58
|
0.61
|
0.54
|
0.59
|
0.44
|
0.58
|
0.61
|
0.53
|
0.57
|
0.72
|
0.55
|
0.57
|
0.68
|
0.73
|
1.00
|
0.64
|
0.66
|
0.76
|
0.56
|
0.56
|
0.59
|
0.64
|
0.56
|
0.53
|
0.49
|
0.66
|
1.00
|
0.79
|
0.48
|
0.63
|
0.55
|
0.60
|
0.55
|
1610 (DAO)
|
0.66
|
0.60
|
1.00
|
1.00
|
0.64
|
1.00
|
0.57
|
0.57
|
1.00
|
0.53
|
0.56
|
0.61
|
0.57
|
0.57
|
0.58
|
0.63
|
0.58
|
0.66
|
0.59
|
0.67
|
0.52
|
0.60
|
0.42
|
0.56
|
0.65
|
0.51
|
0.55
|
0.70
|
0.50
|
0.55
|
0.63
|
0.72
|
1.00
|
0.69
|
0.63
|
0.88
|
0.57
|
0.53
|
0.60
|
0.54
|
0.57
|
0.50
|
0.52
|
0.65
|
0.79
|
1.00
|
0.48
|
0.63
|
0.52
|
0.59
|
0.51
|
4358 (MPV17)
|
0.48
|
0.48
|
0.48
|
0.48
|
0.48
|
0.48
|
0.48
|
0.48
|
0.48
|
0.38
|
0.38
|
0.38
|
0.38
|
0.48
|
0.48
|
0.38
|
0.38
|
0.48
|
0.38
|
0.38
|
0.38
|
0.38
|
0.32
|
0.38
|
0.64
|
0.38
|
0.38
|
0.48
|
0.48
|
0.38
|
0.48
|
0.48
|
0.48
|
0.48
|
0.48
|
0.48
|
0.38
|
0.48
|
0.38
|
0.38
|
0.38
|
0.38
|
0.38
|
0.48
|
0.48
|
0.48
|
1.00
|
0.48
|
1.00
|
0.48
|
0.48
|
3416 (IDE)
|
0.61
|
0.66
|
1.00
|
1.00
|
0.58
|
1.00
|
0.53
|
0.53
|
1.00
|
0.50
|
0.51
|
0.48
|
0.47
|
0.53
|
0.51
|
0.54
|
0.50
|
0.57
|
0.50
|
0.54
|
0.49
|
0.50
|
0.46
|
0.51
|
0.55
|
0.48
|
0.49
|
0.68
|
0.49
|
0.49
|
0.56
|
0.64
|
1.00
|
0.59
|
0.60
|
0.60
|
0.47
|
0.58
|
0.59
|
0.64
|
0.47
|
0.46
|
0.42
|
0.57
|
0.63
|
0.63
|
0.48
|
1.00
|
0.49
|
0.55
|
0.52
|
283927 (NUDT7)
|
0.53
|
0.46
|
0.82
|
0.82
|
0.59
|
0.82
|
0.43
|
0.43
|
0.82
|
0.42
|
0.73
|
0.41
|
0.45
|
0.43
|
0.43
|
0.50
|
0.49
|
0.51
|
0.46
|
0.44
|
0.75
|
0.47
|
0.35
|
0.73
|
0.53
|
0.63
|
0.44
|
0.62
|
0.63
|
0.44
|
0.50
|
0.56
|
0.82
|
0.46
|
0.49
|
0.51
|
0.45
|
0.53
|
0.46
|
0.42
|
0.45
|
0.44
|
0.41
|
0.52
|
0.55
|
0.52
|
1.00
|
0.49
|
1.00
|
0.58
|
0.84
|
6233 (RPS27A)
|
0.62
|
0.56
|
1.00
|
1.00
|
0.83
|
1.00
|
0.49
|
0.49
|
1.00
|
0.37
|
0.46
|
0.37
|
0.41
|
0.49
|
0.45
|
0.54
|
0.46
|
0.54
|
0.46
|
0.40
|
0.40
|
0.46
|
0.39
|
0.46
|
0.51
|
0.40
|
0.45
|
0.65
|
0.40
|
0.45
|
0.53
|
0.69
|
1.00
|
0.50
|
0.52
|
0.59
|
0.41
|
0.43
|
0.46
|
0.44
|
0.41
|
0.40
|
0.33
|
0.54
|
0.60
|
0.59
|
0.48
|
0.55
|
0.58
|
1.00
|
0.41
|
10005 (ACOT8)
|
0.52
|
0.47
|
1.00
|
1.00
|
0.46
|
1.00
|
0.43
|
0.43
|
1.00
|
0.39
|
0.91
|
0.37
|
0.40
|
0.43
|
0.43
|
0.49
|
0.45
|
0.48
|
0.41
|
0.41
|
0.91
|
0.43
|
0.37
|
0.91
|
0.46
|
0.80
|
0.39
|
0.68
|
0.76
|
0.39
|
0.48
|
0.52
|
1.00
|
0.42
|
0.48
|
0.50
|
0.41
|
0.56
|
0.45
|
0.43
|
0.41
|
0.41
|
0.37
|
0.50
|
0.55
|
0.51
|
0.48
|
0.52
|
0.84
|
0.41
|
1.00
|
Association with High Altitude
Protein Official symbol |
Source Organism |
Tissue of Expression |
Level of hypoxia |
Altitude |
Duration of experiment |
Level of expression |
Fold change |
Experiment details |
geographical location |
ethnicity of the patients |
Control group |
Control (Fold change) |
Reference (PMID) |
ECH1 |
Toad |
Heart |
- |
3464 m |
33 day |
downregulated |
-2.032722319 |
RNA-seq |
Tibetan Plateau |
Asiatic toad |
1 |
Zoige (High altitute Toad) Vs Chengdu (Low altitude toad) - |
28673260 |
ECH1 |
Human |
Muscle biopsies |
- |
3500-4500 m |
30 day |
upregulated |
5 |
2-DE |
Himalayas |
Tibetan and nepali |
1 |
Nepali controls residing at 1300m |
14734630 |
Association with TF
TF |
TF Entrez |
Gene |
Gene Entrez |
Type |
PMID |
Database |
YY1 |
7528 |
ECH1 |
1891 |
proximal_filtered |
22955619 |
TRANSFAC |
Gene Ontology
ID |
GO ID |
GO Term |
GO Type |
1891 |
GO:0070062 |
extracellular exosome |
GOTERM_CC_DIRECT |
1891 |
GO:0016853 |
carbon-carbon lyase activity |
GOTERM_MF_DIRECT |
1891 |
GO:0008152 |
metabolic process |
GOTERM_BP_DIRECT |
1891 |
GO:0005102 |
receptor binding |
GOTERM_MF_DIRECT |
1891 |
GO:0016020 |
membrane |
GOTERM_CC_DIRECT |
1891 |
GO:0009062 |
fatty acid catabolic process |
GOTERM_BP_DIRECT |
1891 |
GO:0005739 |
mitochondrion |
GOTERM_CC_DIRECT |
1891 |
GO:0005777 |
peroxisome |
GOTERM_CC_DIRECT |
1891 |
GO:0005515 |
protein binding |
GOTERM_MF_DIRECT |
1891 |
GO:0006635 |
fatty acid beta-oxidation |
GOTERM_BP_DIRECT |
1891 |
GO:0003824 |
catalytic activity |
GOTERM_MF_DIRECT |
Pathways
Human Entrez ID |
KEGG ID |
KEGG Term |
1891 |
hsa04146 |
Peroxisome |
Association with Disease
Protein Official Symbol |
Human Entrez ID |
Disease Name |
Disease Id |
Disease Semantic Type |
Semantic score |
DSI |
DPI |
Disease Type |
Association with Drug
Protein Official Symbol |
Human Entrez ID |
drug_claim_primary_name |
drug_name |
drug_chembl_id |
interaction_types |