ALTITUDEOMICSDB

Alpha-2-antiplasmin

AltitudeomicsDB

Protein Official symbol	SERPINF2
Aliases	SERPINF2 AAP PLI
Chromosomal Location	17
Length	491
Uniprot ID	P08697
EC number	None
Protein family Information(Pfam)	PF00079;
PDB id	None
InterPro ID	IPR033833;IPR023795;IPR023796;IPR000215;IPR036186;IPR042178;IPR042185;
dbSNP	rs2070862 rs2070863 rs36021516 rs121965062 rs1057335 rs57360598

Protein Protein Interaction

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AltitudeomicsDB

Protein 1	Protein 2	Combine Score
FGG	FGB	0.999
FGA	FGB	0.999
FGG	FGA	0.999
AHSG	ALB	0.998
PLG	SERPINE1	0.997
F8	VWF	0.996
ORM2	ORM1	0.995
SERPINE1	PLAT	0.995
VEGFA	EGF	0.993
VEGFA	IGF1	0.993
VEGFA	TGFB1	0.993
SERPINF2	PLG	0.993
SERPINA1	A2M	0.992
VEGFA	HGF	0.992
IGF1	EGF	0.992
AHSG	FGG	0.991
AHSG	FGA	0.989
FN1	ALB	0.989
ORM2	AHSG	0.989
FN1	EGF	0.988
PLG	HRG	0.988
VEGFA	FN1	0.988
AHSG	HRG	0.987
VEGFA	VWF	0.986
AHSG	ORM1	0.986
VEGFA	ALB	0.986
FGA	HRG	0.985
FN1	TGFB1	0.985
VEGFA	THBS1	0.984
EGF	HGF	0.984
PLG	VWF	0.983
FGG	HRG	0.983
SERPINA1	ALB	0.983
VEGFA	SERPINE1	0.982
FGB	HRG	0.982
FGA	ALB	0.982
SERPINF2	PLAT	0.982
VEGFA	PDGFB	0.981
ALB	EGF	0.98
TGFB1	TIMP1	0.98
ALB	ORM1	0.98
FN1	VWF	0.98
FGG	ALB	0.98
VEGFA	IGF2	0.98
PF4	PPBP	0.98
A2M	SERPINF2	0.98
PLG	FGA	0.98
CLU	APP	0.98
ALB	SERPINE1	0.979
ALB	HGF	0.979
FN1	PLG	0.979
SERPING1	KNG1	0.979
SERPINE1	TGFB1	0.979
PLG	FGB	0.979
FN1	SERPINE1	0.979
VWF	THBS1	0.978
EGF	SERPINE1	0.978
VWF	SERPINE1	0.978
THBS1	TIMP1	0.978
IGF1	HGF	0.978
FGG	PLG	0.978
PLG	ALB	0.978
TGFB2	FN1	0.976
SERPINA1	ORM1	0.976
VEGFC	FN1	0.975
PLG	KNG1	0.974
SERPINE1	TIMP1	0.974
A2M	ALB	0.974
IGF1	ALB	0.974
SERPINA1	AHSG	0.974
EGF	TIMP1	0.974
ALB	VWF	0.973
THBS1	HGF	0.973
VEGFA	KNG1	0.973
AHSG	FGB	0.973
VEGFA	PF4	0.973
VEGFA	TIMP1	0.973
EGF	THBS1	0.972
FN1	TIMP1	0.972
FGG	ORM1	0.972
FN1	THBS1	0.972
ALB	KNG1	0.971
KNG1	HRG	0.971
THBS1	TGFB1	0.971
A2M	PLG	0.971
SERPINE1	HGF	0.971
IGF1	SERPINE1	0.97
EGF	KNG1	0.97
VEGFC	THBS1	0.97
FGA	ORM1	0.97
HGF	TGFB1	0.97
ORM2	ALB	0.97
IGF1	TGFB1	0.969
THBS1	SERPINE1	0.969
VEGFA	PLG	0.969
A2M	SERPING1	0.969
KNG1	SERPINE1	0.969
FGB	ALB	0.969
SERPINA1	PLG	0.969
PLG	TIMP1	0.969
FN1	IGF1	0.968
FN1	HGF	0.968
ORM2	FGA	0.967
FN1	TGFB3	0.967
PF4	VWF	0.967
F8	PLG	0.966
PPBP	VWF	0.966
EGF	TGFB1	0.965
IGF2	EGF	0.965
FGB	ORM1	0.965
EGF	VWF	0.965
ALB	APP	0.965
SERPINA1	ORM2	0.965
PLG	EGF	0.964
CLU	IGF1	0.964
ORM1	HRG	0.963
TGFB3	SERPINE1	0.962
ORM2	FGG	0.962
SERPINF2	ALB	0.962
AHSG	KNG1	0.961
FGG	SERPINF2	0.961
A2M	ORM1	0.961
SERPINF2	FGA	0.961
SERPINF2	HRG	0.961
CLU	EGF	0.961
AHSG	A2M	0.96
THBS1	HRG	0.959
ALB	TGFB1	0.959
CLU	ALB	0.958
F8	ALB	0.958
IGF2	ALB	0.958
VEGFA	TMSB4X	0.958
PLG	THBS1	0.958
A2M	KNG1	0.958
AHSG	PLG	0.958
AHSG	SERPINF2	0.957
SERPINA1	FGA	0.957
ORM2	HRG	0.957
PDGFB	EGF	0.957
FN1	A2M	0.957
AHSG	A1BG	0.957
AHSG	MMRN1	0.957
PLG	PPBP	0.957
HGF	TIMP1	0.957
GAS6	HGF	0.956
FGB	F13A1	0.956
PLG	IGF1	0.956
SERPINF2	PPBP	0.956
ALB	TIMP1	0.956
SERPINF2	VWF	0.956
FGA	F13A1	0.956
SERPINA1	FGG	0.955
PF4	THBS1	0.955
ORM2	FGB	0.955
PLG	TGFB1	0.955
A2M	CLU	0.955
VEGFC	HGF	0.954
VEGFC	EGF	0.954
F8	SERPINE1	0.954
PLG	SERPING1	0.954
VEGFC	PDGFB	0.954
SERPINA1	KNG1	0.954
PLG	PF4	0.954
SERPINA1	TGFB1	0.954
FGG	KNG1	0.953
IGF2	FN1	0.953
IGF1	TIMP1	0.953
VEGFA	TGFB2	0.953
A2M	HRG	0.952
SERPINF2	PF4	0.952
TGFB2	EGF	0.952
FGG	F13A1	0.952
A2M	VWF	0.952
FN1	PF4	0.952
CFD	SERPINE1	0.952
SERPINF2	FGB	0.952
ORM2	A2M	0.951
IGF1	VWF	0.951
PPBP	SERPINE1	0.951
SERPINA1	CLU	0.951
SERPINA1	HRG	0.951
TGFB2	IGF1	0.951
SERPINA1	FGB	0.951
A2M	IGF1	0.951
KNG1	VWF	0.951
IGF1	APP	0.95
A2M	APP	0.95
HRG	SERPINE1	0.95
PDGFB	IGF1	0.95
SERPINA1	A1BG	0.95
FN1	KNG1	0.95
F13A1	VWF	0.95
IGF2	HGF	0.95
FGG	A2M	0.95
PDGFB	TGFB1	0.95
SERPINF2	KNG1	0.95
A2M	FGA	0.95
APP	EGF	0.949
FN1	PDGFB	0.949
SERPINA1	SERPINF2	0.949
SERPINA1	FN1	0.949
IGF1	TGFB3	0.949
VWF	HGF	0.948
FGA	KNG1	0.948
A2M	TIMP1	0.948
FGB	KNG1	0.947
CLU	SERPING1	0.947
TGFB2	THBS1	0.947
VWF	TIMP1	0.947
A2M	FGB	0.947
PF4	SERPINE1	0.946
AHSG	CLU	0.946
SERPINF2	ORM1	0.946
TGFB2	SERPINE1	0.946
F8	SERPINF2	0.946
ALB	HRG	0.946
FN1	APP	0.946
IGF2	TGFB1	0.946
FN1	GAS6	0.946
PDGFB	HGF	0.946
SERPINA1	F5	0.945
FN1	CLU	0.945
VEGFC	SERPINE1	0.945
A1BG	HRG	0.945
VEGFC	IGF1	0.945
PROS1	HRG	0.945
CFD	SERPING1	0.944
PF4	HRG	0.944
VEGFA	F13A1	0.944
F5	PLG	0.944
VEGFA	APP	0.943
ALB	A1BG	0.943
SERPINA1	PROS1	0.943
PROS1	FGB	0.943
CLU	TIMP1	0.943
ORM2	SERPINF2	0.943
IGF1	THBS1	0.943
EGF	TGFB3	0.943
PROS1	F5	0.943
PROS1	ALB	0.943
PF4	ALB	0.942
PROS1	FGG	0.942
ACTN1	FN1	0.942
ALB	THBS1	0.942
PROS1	A2M	0.942
FGA	VWF	0.942
PLG	ACTN4	0.942
VEGFC	ALB	0.941
FN1	SERPINF2	0.941
F5	F13A1	0.941
IGF2	TGFB2	0.941
A2M	A1BG	0.941
TGFB2	PDGFB	0.941
TGFB2	TIMP1	0.941
PF4	TIMP1	0.941
VEGFA	CLU	0.941
VEGFA	TGFB3	0.941
FN1	PPBP	0.941
KNG1	ORM1	0.94
KNG1	A1BG	0.94
SERPINA1	TIMP1	0.94
VEGFC	VEGFA	0.94
PDGFB	VWF	0.94
ORM2	A1BG	0.94
TGFB2	SRGN	0.94
VEGFA	PPBP	0.94
SRGN	SERPINE1	0.94
A1BG	ORM1	0.94
A2M	SERPINE1	0.94
F5	SERPINE1	0.94
VEGFC	VWF	0.94
APP	KNG1	0.94
FGB	SERPINE1	0.94
F8	FN1	0.939
PROS1	FGA	0.939
MMRN1	VWF	0.939
F5	FGA	0.939
VEGFC	TIMP1	0.939
IGF2	PDGFB	0.939
F5	VWF	0.939
PF4	EGF	0.939
PDGFB	ALB	0.938
TGFB3	TIMP1	0.938
ALB	SERPING1	0.938
VEGFA	F8	0.938
ALB	ACTN4	0.938
F8	PPBP	0.938
FN1	HRG	0.937
PDGFB	THBS1	0.937
PDGFB	SERPINE1	0.937
SERPINA1	VWF	0.937
PDGFB	TIMP1	0.937
GAS6	ALB	0.937
SERPINF2	SERPINE1	0.936
CLU	KNG1	0.936
TGFB2	A2M	0.936
PROS1	PLG	0.936
AHSG	FN1	0.936
MMRN1	F5	0.936
CLU	HRG	0.935
FN1	FERMT3	0.935
FN1	ACTN4	0.935
F5	FGG	0.935
FN1	FGA	0.935
ORM2	KNG1	0.935
PPBP	THBS1	0.935
SERPING1	VWF	0.935
F5	KNG1	0.935
PLG	APP	0.935
PPBP	EGF	0.935
A2M	TGFB1	0.935
AHSG	F13A1	0.934
VEGFA	GAS6	0.934
PF4	F13A1	0.934
CLU	TGFB1	0.934
SERPINA1	SERPING1	0.934
AHSG	PROS1	0.934
CLU	A1BG	0.934
IGF2	PLG	0.934
FERMT3	SRGN	0.934
IGF2	TIMP1	0.934
VEGFC	PLG	0.934
FGG	VWF	0.934
PPBP	ALB	0.933
VEGFA	SERPINA1	0.933
PPBP	TIMP1	0.933
VEGFC	TGFB2	0.933
F5	FGB	0.933
PROS1	FN1	0.933
HRG	PLAT	0.933
PROS1	SERPINF2	0.933
IGF2	TGFB3	0.933
VEGFC	TGFB1	0.933
AHSG	IGF1	0.933
AHSG	SERPINE1	0.932
PPBP	F13A1	0.932
SERPINA1	F8	0.932
VEGFC	IGF2	0.932
GAS6	THBS1	0.932
THBS1	TGFB3	0.932
FGG	A1BG	0.932
FGB	VWF	0.932
PF4	SRGN	0.932
VWF	TGFB1	0.932
CLU	THBS1	0.932
PDGFB	TGFB3	0.931
VEGFA	HRG	0.931
PDGFB	PLG	0.931
AHSG	SERPING1	0.931
IGF2	SERPINE1	0.931
F8	KNG1	0.931
SERPINF2	CLU	0.931
CLU	PLG	0.931
FN1	FGG	0.93
IGF1	KNG1	0.93
SERPINA1	HGF	0.93
FGG	SERPING1	0.93
F8	EGF	0.93
PF4	TGFB1	0.93
PROS1	F13A1	0.93
SERPINA1	EGF	0.93
F8	F13A1	0.93
F5	A2M	0.93
FN1	FGB	0.93
IGF2	APP	0.93
FN1	F13A1	0.93
A2M	EGF	0.93
FGA	A1BG	0.929
F5	ALB	0.929
CLU	ORM1	0.929
FGG	SERPINE1	0.929
MMRN1	PF4	0.929
PF4	HGF	0.929
IGF1	PF4	0.929
FERMT3	VWF	0.929
IGF2	THBS1	0.929
SERPINF2	SERPING1	0.929
EGF	A1BG	0.929
FGB	A1BG	0.929
PPBP	SRGN	0.929
PROS1	KNG1	0.929
CFD	ALB	0.929
SERPINF2	F13A1	0.928
LEFTY2	EGF	0.928
PROS1	SERPINE1	0.928
SERPING1	TIMP1	0.928
PLG	ORM1	0.928
SERPING1	ORM1	0.928
F8	A2M	0.927
VWF	HRG	0.927
SERPING1	F13A1	0.927
SERPINA1	IGF1	0.927
VEGFC	PF4	0.927
F8	PF4	0.927
FN1	SERPING1	0.927
F5	ORM1	0.927
PROS1	VWF	0.927
ORM2	F5	0.927
AHSG	IGF2	0.927
VEGFA	A2M	0.926
A2M	PPBP	0.926
MMRN1	SRGN	0.926
TGFB2	HGF	0.926
FGA	PF4	0.926
F13A1	SERPINE1	0.926
F5	SERPINF2	0.926
FGA	SERPING1	0.926
FN1	SRGN	0.926
FGA	SERPINE1	0.926
FGG	CLU	0.926
MMRN1	F13A1	0.926
CLU	VWF	0.926
FGA	TGFB3	0.926
PROS1	SERPING1	0.926
PF4	KNG1	0.926
PROS1	F8	0.926
TGFB2	APP	0.926
APP	TIMP1	0.926
ORM2	CLU	0.926
PPBP	SERPING1	0.926
PDGFB	FGA	0.925
GAS6	IGF1	0.925
APP	VWF	0.925
CLU	FGA	0.925
FGA	PPBP	0.925
ORM2	PLG	0.925
ALB	TGFB3	0.925
CFD	IGF1	0.925
F13A1	ORM1	0.925
ALDOA	ACTN1	0.925
SERPINA1	APP	0.925
ALDOA	F8	0.925
CLU	SERPINE1	0.925
APP	TGFB1	0.925
ALDOA	ALB	0.925
PLG	PLAT	0.924
ACTN2	FN1	0.924
F13A1	SRGN	0.924
MMRN1	FERMT3	0.924
IGF2	A2M	0.924
F5	EGF	0.924
SERPING1	SERPINE1	0.924
TMSB4X	PPBP	0.924
F8	FGG	0.923
TMSB4X	PF4	0.923
PPBP	HGF	0.923
PROS1	ORM1	0.923
ALDOA	ACTN4	0.923
TGFB2	PLG	0.923
FGB	SERPING1	0.923
VEGFA	ACTN4	0.923
VEGFA	CFD	0.923
ACTN2	ALDOA	0.923
IGF2	FGA	0.923
LEFTY2	TGFB3	0.923
KNG1	F13A1	0.923
SERPINA1	PPBP	0.923
VWF	TGFB3	0.923
A1BG	HGF	0.923
PDGFB	APP	0.923
F5	PF4	0.923
ACTN1	TMSB4X	0.922
IGF2	CLU	0.922
PPBP	KNG1	0.922
AHSG	HGF	0.922
VEGFA	ALDOA	0.922
TGFB2	ALB	0.922
IGF2	IGF1	0.922
CFD	CLU	0.922
TGFB3	HGF	0.922
PLG	F13A1	0.922
A2M	F13A1	0.922
F13A1	TGFB3	0.922
TGFB2	FGA	0.922
ACTN1	TGFB1	0.922
APP	SERPINE1	0.921
TGFB2	CLU	0.921
PPBP	HRG	0.921
KNG1	TGFB1	0.921
PF4	SERPING1	0.921
VEGFA	F5	0.921
FGA	THBS1	0.921
TMSB4X	FN1	0.921
KNG1	TIMP1	0.921
AHSG	F5	0.921
PPBP	TGFB1	0.921
F5	FN1	0.921
SRGN	HGF	0.921
AHSG	TIMP1	0.92
ACTN1	THBS1	0.92
ACTN2	TGFB3	0.92
SERPINA1	F13A1	0.92
PDGFB	PPBP	0.92
SERPINA1	TMSB4X	0.92
AHSG	ALDOA	0.92
APP	THBS1	0.919
CLU	FGB	0.919
KNG1	HGF	0.919
SERPINA1	SERPINE1	0.919
ACTN1	EGF	0.919
F8	SERPING1	0.919
VEGFA	SERPING1	0.919
EGF	ACTN4	0.919
IGF1	A1BG	0.919
FGG	EGF	0.919
MMRN1	THBS1	0.919
A2M	THBS1	0.919
ALDOA	FGB	0.919
MMRN1	PPBP	0.919
PDGFB	PF4	0.919
VEGFA	AHSG	0.919
SERPING1	THBS1	0.919
IGF1	F13A1	0.919
F13A1	THBS1	0.918
ACTN2	TGFB1	0.918
CFD	PDGFB	0.918
SERPINF2	A1BG	0.918
A2M	SRGN	0.918
VEGFC	GAS6	0.918
SERPING1	A1BG	0.918
IGF1	PPBP	0.918
IGF1	ACTN4	0.918
F8	THBS1	0.918
PROS1	APP	0.918
IGF2	FGB	0.918
SERPINA1	PF4	0.918
GAS6	VWF	0.918
GAS6	EGF	0.918
ACTN1	IGF1	0.918
FGA	TGFB1	0.918
KNG1	THBS1	0.918
VEGFA	LEFTY2	0.918
TMSB4X	F13A1	0.918
A2M	TGFB3	0.918
FGB	THBS1	0.918
THBS1	SRGN	0.918
FGB	FERMT3	0.918
SERPINA1	THBS1	0.918
VEGFA	PROS1	0.918
CFD	TIMP1	0.918
A2M	PF4	0.917
VEGFA	SERPINF2	0.917
SERPINA1	ALDOA	0.917
VEGFC	TGFB3	0.917
FGA	FERMT3	0.917
TGFB2	LEFTY2	0.917
PDGFB	FGB	0.917
IGF2	VWF	0.917
FGG	PDGFB	0.917
ALB	SRGN	0.917
APP	TGFB3	0.917
FN1	A1BG	0.917
PROS1	CLU	0.917
SERPINF2	APP	0.917
SERPINF2	TIMP1	0.917
IGF2	CFD	0.917
VEGFA	SRGN	0.917
ACTN1	ALB	0.917
SERPING1	HRG	0.916
LEFTY2	ALB	0.916
ALDOA	FGG	0.916
CLU	PF4	0.916
A2M	HGF	0.916
ALDOA	FGA	0.916
PLG	A1BG	0.916
SERPINA1	IGF2	0.916
MMRN1	CLU	0.916
TMSB4X	SRGN	0.916
CLU	PPBP	0.916
TMSB4X	SERPINE1	0.916
IGF2	FGG	0.916
ALDOA	IGF1	0.916
FERMT3	THBS1	0.916
PLG	SRGN	0.916
VEGFC	PPBP	0.916
CLU	HGF	0.916
EGF	SRGN	0.915
IGF2	ACTN4	0.915
PF4	FERMT3	0.915
VEGFA	A1BG	0.915
PROS1	IGF1	0.915
CFD	PF4	0.915
GAS6	SERPINE1	0.915
SERPINA1	PDGFB	0.915
CFD	EGF	0.915
MMRN1	FGB	0.915
TGFB2	VWF	0.915
F8	FGA	0.915
CFD	VWF	0.915
LEFTY2	TGFB1	0.915
AHSG	EGF	0.915
ACTN4	SERPINE1	0.915
ACTN1	TGFB2	0.915
ORM2	SERPING1	0.915
ALDOA	SERPINF2	0.915
AHSG	THBS1	0.915
FGA	APP	0.915
FGA	EGF	0.915
TMSB4X	FGA	0.915
GAS6	TGFB1	0.915
ACTN2	ALB	0.915
EGF	HRG	0.915
ACTN1	SERPINE1	0.915
F8	IGF1	0.915
PLG	TGFB3	0.915
FGB	EGF	0.915
LEFTY2	FN1	0.914
ACTN2	IGF1	0.914
FGB	IGF1	0.914
AHSG	CFD	0.914
SRGN	TIMP1	0.914
ACTN2	VWF	0.914
APP	SERPING1	0.914
SERPINA1	CFD	0.914
TGFB2	GAS6	0.914
MMRN1	KNG1	0.914
ACTN1	CLU	0.914
F5	F8	0.914
FN1	CFD	0.914
ACTN1	FERMT3	0.914
PROS1	EGF	0.914
EGF	F13A1	0.914
MMRN1	F8	0.914
PROS1	THBS1	0.914
AHSG	APP	0.913
GAS6	APP	0.913
TGFB2	PF4	0.913
MMRN1	A2M	0.913
FGA	IGF1	0.913
F5	HRG	0.913
FGG	FERMT3	0.913
F8	FGB	0.913
F5	A1BG	0.913
FERMT3	TGFB1	0.913
F5	SERPING1	0.913
A2M	ACTN4	0.913
SRGN	TGFB1	0.913
IGF2	GAS6	0.913
PROS1	ACTN4	0.913
ACTN1	A2M	0.913
MMRN1	FN1	0.913
ORM2	CFD	0.913
ALDOA	PROS1	0.913
FERMT3	F13A1	0.913
FN1	ORM1	0.913
PPBP	FERMT3	0.913
VWF	SRGN	0.913
F13A1	TGFB1	0.912
TMSB4X	TGFB1	0.912
GAS6	PF4	0.912
GAS6	PDGFB	0.912
AHSG	PF4	0.912
MMRN1	HRG	0.912
ALB	F13A1	0.912
IGF2	SERPINF2	0.912
IGF1	SERPING1	0.912
FGB	TGFB1	0.912
AHSG	VWF	0.912
PLG	HGF	0.912
ACTN2	EGF	0.912
CLU	SRGN	0.912
PROS1	A1BG	0.912
ORM2	TMSB4X	0.912
ORM2	TIMP1	0.912
ORM2	PROS1	0.912
F8	HGF	0.912
CFD	A2M	0.912
AHSG	FERMT3	0.912
IGF2	LEFTY2	0.912
MMRN1	SERPINF2	0.911
ALDOA	PLG	0.911
ORM1	SERPINE1	0.911
TMSB4X	A2M	0.911
PROS1	TGFB2	0.911
SERPINA1	SRGN	0.911
F13A1	TIMP1	0.911
GAS6	ACTN4	0.911
PROS1	TIMP1	0.911
ALDOA	TIMP1	0.911
IGF2	KNG1	0.911
TMSB4X	IGF1	0.911
AHSG	LEFTY2	0.911
AHSG	TGFB1	0.911
FGG	THBS1	0.911
TMSB4X	HGF	0.911
F5	PPBP	0.911
CFD	ORM1	0.911
VEGFC	KNG1	0.91
ORM1	TIMP1	0.91
ALDOA	APP	0.91
ACTN1	TIMP1	0.91
MMRN1	ALB	0.91
ALDOA	CLU	0.91
SERPING1	TGFB1	0.91
CFD	PPBP	0.91
TMSB4X	ALB	0.91
ALDOA	A2M	0.91
CFD	KNG1	0.91
MMRN1	EGF	0.91
IGF2	PF4	0.91
ALDOA	FN1	0.91
TGFB2	PPBP	0.91
TGFB2	TGFB3	0.91
SERPINF2	EGF	0.91
APP	HRG	0.91
GAS6	SERPINF2	0.91
ALDOA	EGF	0.91
VEGFC	SERPINA1	0.91
GAS6	TIMP1	0.91
CFD	SRGN	0.91
PF4	APP	0.91
SERPING1	SRGN	0.91
VEGFA	ACTN1	0.91
CFD	APP	0.91
TMSB4X	EGF	0.91
PDGFB	KNG1	0.91
GAS6	HRG	0.91
CFD	TGFB1	0.91
GAS6	KNG1	0.909
GAS6	SERPING1	0.909
THBS1	ACTN4	0.909
SERPING1	TGFB3	0.909
IGF2	PROS1	0.909
IGF2	SERPING1	0.909
SERPINF2	TGFB1	0.909
ACTN4	TGFB1	0.909
AHSG	GAS6	0.909
FGG	IGF1	0.909
ALDOA	HRG	0.909
ACTN2	TGFB2	0.909
PPBP	TGFB3	0.909
VEGFC	F5	0.909
VEGFA	FGA	0.909
MMRN1	PROS1	0.909
FGG	APP	0.909
TMSB4X	ORM1	0.909
ACTN1	ACTN4	0.908
VEGFC	APP	0.908
VEGFC	F8	0.908
ACTN1	APP	0.908
APP	ACTN4	0.908
F8	GAS6	0.908
THBS1	ORM1	0.908
AHSG	TMSB4X	0.908
PDGFB	A2M	0.908
APP	HGF	0.908
ACTN2	CLU	0.908
TOR4A	TGFB1	0.908
SERPINA1	GAS6	0.908
PROS1	TGFB1	0.908
MMRN1	SERPING1	0.908
MMRN1	PLG	0.908
ALDOA	TGFB3	0.908
PROS1	GAS6	0.908
FGB	APP	0.908
CLU	TGFB3	0.908
VEGFA	ACTN2	0.908
ACTN1	F13A1	0.908
F5	THBS1	0.908
SERPINF2	THBS1	0.908
LEFTY2	FGG	0.908
IGF2	ALDOA	0.908
APP	SRGN	0.908
VEGFC	AHSG	0.908
F5	SRGN	0.908
IGF1	ORM1	0.908
ACTN2	APP	0.907
TGFB2	TGFB1	0.907
ACTN1	PF4	0.907
CFD	A1BG	0.907
PROS1	PF4	0.907
F5	CLU	0.907
ACTN4	TIMP1	0.907
CFD	F13A1	0.907
F13A1	HRG	0.907
F13A1	ACTN4	0.907
IGF2	TMSB4X	0.907
VEGFA	FGB	0.907
ALB	FERMT3	0.907
GAS6	CLU	0.907
PROS1	PPBP	0.907
IGF2	A1BG	0.907
CFD	PLG	0.907
ORM2	ALDOA	0.907
GAS6	TGFB3	0.907
ALDOA	TGFB2	0.907
CFD	FERMT3	0.907
ACTN2	PROS1	0.907
SERPINF2	IGF1	0.907
VEGFA	ORM1	0.907
GAS6	F13A1	0.907
IGF2	ORM1	0.907
ALDOA	ORM1	0.907
ACTN1	PPBP	0.907
ACTN2	IGF2	0.907
F5	HGF	0.907
KNG1	ACTN4	0.907
F5	TGFB1	0.907
GAS6	PLG	0.907
SERPINF2	HGF	0.907
VEGFA	FGG	0.907
ORM2	IGF2	0.907
TMSB4X	PLG	0.907
AHSG	PPBP	0.907
SERPING1	EGF	0.907
TMSB4X	TIMP1	0.907
PF4	TGFB3	0.907
SERPINA1	ACTN1	0.907
CLU	F13A1	0.907
TMSB4X	THBS1	0.906
ACTN1	F5	0.906
TGFB3	TGFB1	0.906
FERMT3	ACTN4	0.906
ACTN1	GAS6	0.906
F8	TIMP1	0.906
APP	ORM1	0.906
KNG1	SRGN	0.906
IGF2	ACTN1	0.906
TGFB2	ACTN4	0.906
PROS1	SRGN	0.906
ACTN1	FGA	0.906
TMSB4X	TGFB3	0.906
F8	TGFB1	0.906
MMRN1	CFD	0.906
F8	APP	0.906
ORM2	F13A1	0.906
LEFTY2	FGB	0.906
F8	HRG	0.906
SERPINA1	TGFB2	0.906
HRG	HGF	0.906
TMSB4X	FGG	0.906
KNG1	TGFB3	0.906
ACTN2	FERMT3	0.906
MMRN1	TGFB1	0.906
MMRN1	ACTN1	0.906
ORM2	APP	0.906
ACTN1	SERPINF2	0.906
PDGFB	HRG	0.906
FGG	TIMP1	0.905
MMRN1	ORM1	0.905
ACTN1	PROS1	0.905
TGFB2	SERPING1	0.905
PROS1	CFD	0.905
VEGFA	MMRN1	0.905
HRG	TIMP1	0.905
SERPINA1	ACTN4	0.905
CFD	THBS1	0.905
VEGFC	ACTN4	0.905
LEFTY2	IGF1	0.905
ALDOA	TGFB1	0.905
FGG	TGFB3	0.905
CFD	FGB	0.905
F5	TGFB3	0.905
FGA	TIMP1	0.905
TGFB2	FGB	0.905
TOR4A	CFD	0.905
A1BG	THBS1	0.905
FGB	TIMP1	0.905
ORM1	HGF	0.905
ACTN2	A2M	0.905
ACTN1	FGB	0.905
ORM2	MMRN1	0.905
F8	SRGN	0.905
PDGFB	SERPINF2	0.905
PF4	ORM1	0.905
VEGFA	FERMT3	0.905
IGF2	PPBP	0.905
VEGFC	A2M	0.905
IGF2	SRGN	0.905
SERPINA1	TGFB3	0.905
CFD	HGF	0.905
CFD	FGA	0.905
F13A1	HGF	0.905
TOR4A	FERMT3	0.905
LEFTY2	FGA	0.905
LEFTY2	TIMP1	0.904
TMSB4X	KNG1	0.904
F5	FERMT3	0.904
ACTN1	TGFB3	0.904
MMRN1	APP	0.904
ACTN2	HGF	0.904
ACTN1	F8	0.904
LEFTY2	THBS1	0.904
CFD	SERPINF2	0.904
FGB	TGFB3	0.904
ACTN2	MMRN1	0.904
SERPINA1	FERMT3	0.904
F8	PDGFB	0.904
ACTN1	VWF	0.904
EGF	ORM1	0.904
VEGFC	CLU	0.904
SERPING1	HGF	0.904
PPBP	APP	0.904
ALDOA	CFD	0.904
ORM2	SERPINE1	0.904
TOR4A	SERPINF2	0.904
ORM2	LEFTY2	0.904
ACTN1	KNG1	0.904
FERMT3	EGF	0.904
PROS1	PDGFB	0.904
PROS1	TGFB3	0.904
F5	IGF1	0.904
FGG	PPBP	0.904
VWF	ORM1	0.904
ALDOA	F5	0.904
VEGFC	SERPING1	0.904
ALDOA	PPBP	0.904
TMSB4X	F8	0.904
PROS1	HGF	0.904
FGA	ACTN4	0.904
IGF2	F13A1	0.904
ORM2	HGF	0.904
F13A1	A1BG	0.904
TOR4A	TIMP1	0.904
VEGFC	SERPINF2	0.904
GAS6	A2M	0.904
ACTN2	SERPINA1	0.904
TOR4A	SRGN	0.904
FGG	CFD	0.903
FGG	TGFB1	0.903
ALDOA	THBS1	0.903
F8	TGFB3	0.903
LEFTY2	SERPINF2	0.903
VEGFC	FGG	0.903
TOR4A	THBS1	0.903
F8	CLU	0.903
ALDOA	SERPINE1	0.903
VEGFC	HRG	0.903
CLU	ACTN4	0.903
TOR4A	SERPINE1	0.903
MMRN1	HGF	0.903
ORM2	PF4	0.903
VEGFC	MMRN1	0.903
TMSB4X	VWF	0.903
FERMT3	TIMP1	0.903
ORM2	SRGN	0.903
SERPINF2	ACTN4	0.903
MMRN1	GAS6	0.903
SERPINA1	MMRN1	0.903
GAS6	PPBP	0.903
LEFTY2	PDGFB	0.903
ORM2	FN1	0.903
TMSB4X	FERMT3	0.903
PDGFB	CLU	0.903
ACTN2	AHSG	0.903
ACTN2	F13A1	0.903
PF4	A1BG	0.903
TMSB4X	CLU	0.903
TMSB4X	FGB	0.903
VEGFC	F13A1	0.903
TMSB4X	ACTN4	0.903
A1BG	TIMP1	0.903
ORM1	SRGN	0.903
IGF1	HRG	0.903
ACTN2	F5	0.903
APP	A1BG	0.903
VEGFC	ACTN1	0.903
AHSG	F8	0.903
F5	APP	0.903
SERPINF2	SRGN	0.903
ALDOA	MMRN1	0.903
LEFTY2	ORM1	0.903
TMSB4X	GAS6	0.903
MMRN1	TIMP1	0.903
MMRN1	TGFB2	0.903
VEGFC	PROS1	0.903
ACTN1	PLG	0.902
ALDOA	VWF	0.902
ORM1	ACTN4	0.902
ACTN2	F8	0.902
ALDOA	SERPING1	0.902
PPBP	A1BG	0.902
FERMT3	SERPING1	0.902
TGFB2	F13A1	0.902
TGFB2	F8	0.902
ACTN2	SERPINE1	0.902
PDGFB	F13A1	0.902
SERPINA1	TOR4A	0.902
ACTN2	SERPING1	0.902
MMRN1	SERPINE1	0.902
LEFTY2	SERPINE1	0.902
MMRN1	TGFB3	0.902
SERPINF2	TGFB3	0.902
TGFB2	SERPINF2	0.902
FGA	HGF	0.902
ACTN2	THBS1	0.902
APP	FERMT3	0.902
FGB	HGF	0.902
IGF2	HRG	0.902
FGB	SRGN	0.902
F5	TGFB2	0.902
MMRN1	ACTN4	0.902
TOR4A	GAS6	0.902
GAS6	FGB	0.902
TGFB2	KNG1	0.902
TOR4A	ACTN4	0.902
CFD	HRG	0.902
SERPINF2	FERMT3	0.902
TOR4A	PPBP	0.902
ALDOA	KNG1	0.902
PROS1	TOR4A	0.902
GAS6	ORM1	0.902
TOR4A	VWF	0.902
MMRN1	IGF1	0.902
ACTN2	SERPINF2	0.902
IGF2	F5	0.902
TOR4A	SERPING1	0.902
ORM2	IGF1	0.902
SERPING1	ACTN4	0.902
ACTN2	KNG1	0.902
TMSB4X	PDGFB	0.902
ACTN2	TIMP1	0.902
FGG	HGF	0.902
ALDOA	PDGFB	0.902
AHSG	TGFB2	0.902
VWF	ACTN4	0.902
SRGN	TGFB3	0.902
PDGFB	SRGN	0.902
FGB	PPBP	0.902
A1BG	SERPINE1	0.902
PF4	ACTN4	0.902
TOR4A	F13A1	0.902
ACTN4	HRG	0.902
TMSB4X	SERPINF2	0.902
ACTN1	SERPING1	0.902
FERMT3	HGF	0.902
ACTN2	ORM1	0.901
TMSB4X	SERPING1	0.901
ACTN4	HGF	0.901
AHSG	SRGN	0.901
ACTN2	PPBP	0.901
VEGFC	TOR4A	0.901
ACTN1	SRGN	0.901
TOR4A	HGF	0.901
ACTN2	ORM2	0.901
PDGFB	FERMT3	0.901
TGFB2	TOR4A	0.901
AHSG	ACTN1	0.901
TOR4A	APP	0.901
ALDOA	TMSB4X	0.901
VEGFA	ORM2	0.901
VEGFC	TMSB4X	0.901
IGF1	FERMT3	0.901
ACTN1	ORM1	0.901
TMSB4X	TGFB2	0.901
APP	F13A1	0.901
ACTN2	ACTN1	0.901
ORM2	VWF	0.901
F5	GAS6	0.901
LEFTY2	GAS6	0.901
ALDOA	GAS6	0.901
ORM2	TGFB2	0.901
PPBP	ORM1	0.901
CFD	GAS6	0.901
TGFB2	CFD	0.901
A1BG	ACTN4	0.901
F8	CFD	0.901
ACTN2	ACTN4	0.901
ACTN1	HGF	0.901
F8	ACTN4	0.901
ORM1	TGFB1	0.901
A1BG	TGFB1	0.901
LEFTY2	PLG	0.9
LEFTY2	HGF	0.9
FGG	PF4	0.9
ACTN2	TMSB4X	0.9
TOR4A	TGFB3	0.9
ACTN2	FGG	0.9
PROS1	FERMT3	0.9
AHSG	TOR4A	0.9
TMSB4X	APP	0.9
ACTN2	CFD	0.9
GAS6	SRGN	0.9
VEGFC	FGA	0.9
GAS6	A1BG	0.9
PPBP	ACTN4	0.9
ACTN4	TGFB3	0.9
ACTN1	CFD	0.9
ALDOA	LEFTY2	0.9
LEFTY2	TOR4A	0.9
ORM2	EGF	0.9
F8	FERMT3	0.9
ACTN1	A1BG	0.9
VEGFC	CFD	0.9
MMRN1	PDGFB	0.9
IGF2	TOR4A	0.9
A1BG	SRGN	0.9
TOR4A	EGF	0.9
LEFTY2	F8	0.9
ORM2	THBS1	0.9
ACTN2	GAS6	0.9
FGA	SRGN	0.9
PLG	FERMT3	0.9
PDGFB	ORM1	0.9
LEFTY2	APP	0.9
ACTN2	PLG	0.9
ALDOA	F13A1	0.9
VEGFC	SRGN	0.9
TGFB2	HRG	0.9
VEGFC	ORM2	0.9
TOR4A	PF4	0.9
ORM2	FERMT3	0.9
TOR4A	PDGFB	0.9
ALDOA	A1BG	0.9
FGB	PF4	0.9
MMRN1	FGA	0.9
IGF2	F8	0.9
ACTN1	HRG	0.9
F5	PDGFB	0.9
IGF2	FERMT3	0.9
GAS6	FERMT3	0.9
TGFB2	FERMT3	0.9
AHSG	PDGFB	0.9
VEGFC	A1BG	0.9
TOR4A	HRG	0.9
ACTN2	FGA	0.9
F5	ACTN4	0.9
AHSG	ACTN4	0.9
TOR4A	FGB	0.9
ACTN2	TOR4A	0.9
FERMT3	KNG1	0.9
VEGFC	ORM1	0.9
ORM2	ACTN4	0.9
FERMT3	HRG	0.9
F8	ORM1	0.9
ALDOA	PF4	0.9
PROS1	TMSB4X	0.9
TOR4A	CLU	0.9
A2M	FERMT3	0.9
F5	CFD	0.9
ALDOA	HGF	0.9
PDGFB	ACTN4	0.9
ACTN2	FGB	0.9
FGG	ACTN4	0.9
ORM1	TGFB3	0.9
F5	LEFTY2	0.9
TOR4A	FGG	0.9
ORM2	GAS6	0.9
ACTN1	LEFTY2	0.9
ACTN1	TOR4A	0.9
ACTN2	A1BG	0.9
IGF2	MMRN1	0.9
LEFTY2	HRG	0.9
PDGFB	A1BG	0.9
ORM2	PDGFB	0.9
F8	A1BG	0.9
TOR4A	ORM1	0.9
PROS1	LEFTY2	0.9
TGFB2	A1BG	0.9
ORM2	TGFB1	0.9
F8	TOR4A	0.9
MMRN1	A1BG	0.9
LEFTY2	KNG1	0.9
TGFB3	HRG	0.9
TOR4A	FN1	0.9
A1BG	VWF	0.9
LEFTY2	PPBP	0.9
TMSB4X	A1BG	0.9
LEFTY2	SRGN	0.9
ORM2	TOR4A	0.9
SRGN	HRG	0.9
TOR4A	ALB	0.9
TMSB4X	CFD	0.9
TMSB4X	F5	0.9
ALDOA	FERMT3	0.9
VEGFA	TOR4A	0.9
FERMT3	TGFB3	0.9
FGG	GAS6	0.9
LEFTY2	ACTN4	0.9
TGFB2	ORM1	0.9
ACTN2	LEFTY2	0.9
F5	TOR4A	0.9
FGG	SRGN	0.9
LEFTY2	VWF	0.9
TGFB2	FGG	0.9
TMSB4X	LEFTY2	0.9
TOR4A	PLG	0.9
HRG	TGFB1	0.9
VEGFC	FERMT3	0.9
LEFTY2	CLU	0.9
LEFTY2	PF4	0.9
GAS6	FGA	0.9
VEGFC	ACTN2	0.9
ALDOA	SRGN	0.9
TOR4A	KNG1	0.9
ACTN2	SRGN	0.9
ORM2	ACTN1	0.9
MMRN1	TOR4A	0.9
A1BG	TGFB3	0.9
LEFTY2	A2M	0.9
TOR4A	FGA	0.9
ORM2	F8	0.9
FERMT3	ORM1	0.9
ACTN2	PDGFB	0.9
TMSB4X	HRG	0.9
ACTN2	PF4	0.9
LEFTY2	FERMT3	0.9
AHSG	TGFB3	0.9
LEFTY2	F13A1	0.9
FERMT3	SERPINE1	0.9
VEGFC	FGB	0.9
TOR4A	A2M	0.9
ACTN1	FGG	0.9
MMRN1	TMSB4X	0.9
FGB	ACTN4	0.9
ORM2	PPBP	0.9
ORM2	TGFB3	0.9
TOR4A	IGF1	0.9
ALDOA	TOR4A	0.9
CFD	TGFB3	0.9
VEGFC	ALDOA	0.9
MMRN1	LEFTY2	0.9
PDGFB	SERPING1	0.9
CFD	ACTN4	0.9
SERPINA1	LEFTY2	0.9
TOR4A	A1BG	0.9
MMRN1	FGG	0.9
LEFTY2	A1BG	0.9
FERMT3	A1BG	0.9
CLU	FERMT3	0.9
LEFTY2	SERPING1	0.9
ACTN4	SRGN	0.9
ACTN1	PDGFB	0.9
TMSB4X	TOR4A	0.9
VEGFC	LEFTY2	0.9
LEFTY2	CFD	0.9
ACTN2	HRG	0.9
IGF1	SRGN	0.9
F5	TIMP1	0.9

Gene Ontology Semantic Similarity

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#	1278 (COL1A2)	7471 (WNT1)	10491 (CRTAP)	5479 (PPIB)	1281 (COL3A1)	4041 (LRP5)	7422 (VEGFA)	649 (BMP1)	5340 (PLG)	1277 (COL1A1)	5352 (PLOD2)	1306 (COL15A1)	7058 (THBS2)	10417 (SPON2)	4040 (LRP6)	2247 (FGF2)	60681 (FKBP10)	121340 (SP7)	55151 (TMEM38B)	7439 (BEST1)	5306 (PITPNA)	4641 (MYO1C)	4643 (MYO1E)	7531 (YWHAE)	5176 (SERPINF1)	285 (ANGPT2)	9852 (EPM2AIP1)	5358 (PLS3)	6121 (RPE65)	57104 (PNPLA2)	8578 (SCARF1)	7057 (THBS1)	3075 (CFH)	9315 (NREP)	51008 (ASCC1)	8492 (PRSS12)	51438 (MAGEC2)	64092 (SAMSN1)	284293 (HMSD)	84432 (PROK1)	6652 (SORD)	7780 (SLC30A2)	5118 (PCOLCE)	5327 (PLAT)
1278 (COL1A2)	1.00	0.49	0.71	0.66	0.91	0.58	0.66	0.53	0.66	0.90	0.13	1.00	1.00	1.00	0.59	0.49	0.25	0.49	0.06	0.50	0.25	0.72	0.55	0.62	0.66	0.72	0.69	0.51	0.22	0.12	0.25	0.64	0.66	1.00	1.00	0.15	0.72	0.43	0.12	0.69	0.52	0.66	0.63	0.69
7471 (WNT1)	0.49	1.00	0.49	0.51	0.49	0.43	0.60	0.39	0.50	0.51	0.17	0.34	0.69	0.69	0.50	0.45	0.26	0.46	0.06	0.32	0.21	0.58	0.39	0.46	0.46	0.60	0.57	0.36	0.19	0.13	0.22	0.43	0.45	0.69	0.69	0.18	0.50	0.39	0.15	0.86	0.36	0.46	0.44	0.55
10491 (CRTAP)	0.71	0.49	1.00	1.00	0.72	0.71	0.71	0.71	0.87	0.71	0.09	0.19	0.71	0.71	0.71	0.71	0.25	0.49	0.06	0.58	0.25	0.71	0.74	0.72	0.71	0.71	0.71	0.74	0.23	0.10	0.43	0.87	0.71	0.71	0.71	0.11	0.71	0.43	0.09	0.49	0.58	0.71	0.87	0.71
5479 (PPIB)	0.66	0.51	1.00	1.00	0.65	0.55	0.62	0.54	0.68	0.69	0.19	0.26	1.00	1.00	0.54	0.48	0.48	0.54	0.06	0.42	0.24	0.67	0.56	0.67	0.61	0.67	0.69	0.74	0.24	0.14	0.28	0.66	0.61	1.00	1.00	0.23	0.67	0.56	0.12	0.69	0.49	0.61	0.67	0.66
1281 (COL3A1)	0.91	0.49	0.72	0.65	1.00	0.54	0.62	0.48	0.65	0.84	0.13	1.00	1.00	1.00	0.54	0.46	0.24	0.46	0.06	0.40	0.24	0.70	0.52	0.60	0.61	0.70	0.62	0.54	0.21	0.12	0.25	0.66	0.61	1.00	1.00	0.15	0.68	0.41	0.12	0.69	0.44	0.61	0.60	0.67
4041 (LRP5)	0.58	0.43	0.71	0.55	0.54	1.00	0.58	0.39	0.58	0.61	0.13	0.26	1.00	1.00	0.80	0.40	0.20	0.36	0.06	0.32	0.21	0.57	0.44	0.54	0.48	0.57	0.52	0.51	0.19	0.11	0.54	0.56	0.50	1.00	1.00	0.15	0.55	0.33	0.12	0.69	0.38	0.48	0.48	0.57
7422 (VEGFA)	0.66	0.60	0.71	0.62	0.62	0.58	1.00	0.55	0.65	0.68	0.17	0.34	1.00	1.00	0.64	0.64	0.24	0.42	0.06	0.49	0.27	0.69	0.57	0.62	0.61	0.69	0.64	0.51	0.25	0.11	0.24	0.69	0.69	1.00	1.00	0.18	0.63	0.37	0.15	0.70	0.51	0.60	0.67	0.68
649 (BMP1)	0.53	0.39	0.71	0.54	0.48	0.39	0.55	1.00	0.82	0.54	0.24	0.26	1.00	1.00	0.45	0.38	0.28	0.31	0.06	0.27	0.19	0.49	0.49	0.51	0.39	0.49	0.45	0.51	0.34	0.31	0.18	0.53	0.42	1.00	1.00	0.83	0.46	0.28	0.12	0.69	0.38	0.39	0.41	0.80
5340 (PLG)	0.66	0.50	0.87	0.68	0.65	0.58	0.65	0.82	1.00	0.68	0.16	0.26	1.00	1.00	0.60	0.53	0.26	0.48	0.06	0.45	0.23	0.69	0.60	0.63	0.62	0.69	0.62	0.64	0.27	0.17	0.24	0.63	0.62	1.00	1.00	1.00	0.66	0.39	0.12	0.84	0.48	0.62	0.62	0.85
1277 (COL1A1)	0.90	0.51	0.71	0.69	0.84	0.61	0.68	0.54	0.68	1.00	0.13	0.26	1.00	1.00	0.60	0.48	0.26	0.53	0.06	0.52	0.26	0.79	0.57	0.63	0.72	0.79	0.75	0.51	0.23	0.12	0.26	0.66	0.71	1.00	1.00	0.15	0.80	0.48	0.12	0.69	0.54	0.72	0.66	0.74
5352 (PLOD2)	0.13	0.17	0.09	0.19	0.13	0.13	0.17	0.24	0.16	0.13	1.00	0.13	0.13	0.13	0.13	0.17	0.19	0.10	0.04	0.10	0.08	0.13	0.13	0.13	0.13	0.13	0.13	0.07	0.16	0.15	0.09	0.13	0.13	0.13	0.13	0.16	0.13	0.08	0.06	0.09	0.28	0.13	0.13	0.13
1306 (COL15A1)	1.00	0.34	0.19	0.26	1.00	0.26	0.34	0.26	0.26	0.26	0.13	1.00	0.26	0.26	0.26	0.34	0.18	0.21	0.07	0.21	0.16	0.26	0.26	0.26	0.26	0.26	0.26	0.13	0.16	0.14	0.18	0.26	0.26	0.26	0.26	0.15	0.26	0.16	0.12	0.18	0.26	0.26	0.26	0.26
7058 (THBS2)	1.00	0.69	0.71	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.13	0.26	1.00	1.00	1.00	1.00	0.33	0.69	0.07	0.82	0.34	1.00	1.00	1.00	1.00	1.00	1.00	0.51	0.31	0.14	0.36	1.00	1.00	1.00	1.00	0.15	1.00	0.60	0.12	0.69	0.82	1.00	1.00	1.00
10417 (SPON2)	1.00	0.69	0.71	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.13	0.26	1.00	1.00	1.00	1.00	0.33	0.69	0.07	0.82	0.34	1.00	1.00	1.00	1.00	1.00	1.00	0.51	0.31	0.14	0.36	1.00	1.00	1.00	1.00	0.15	1.00	0.60	0.12	0.69	0.82	1.00	1.00	1.00
4040 (LRP6)	0.59	0.50	0.71	0.54	0.54	0.80	0.64	0.45	0.60	0.60	0.13	0.26	1.00	1.00	1.00	0.48	0.20	0.36	0.07	0.44	0.24	0.58	0.48	0.55	0.54	0.59	0.55	0.51	0.19	0.11	0.42	0.57	0.52	1.00	1.00	0.15	0.54	0.32	0.42	0.86	0.45	0.51	0.53	0.58
2247 (FGF2)	0.49	0.45	0.71	0.48	0.46	0.40	0.64	0.38	0.53	0.48	0.17	0.34	1.00	1.00	0.48	1.00	0.20	0.30	0.05	0.30	0.19	0.49	0.40	0.55	0.41	0.49	0.43	0.51	0.19	0.15	0.18	0.50	0.42	1.00	1.00	0.18	0.44	0.26	0.22	0.70	0.35	0.40	0.42	0.50
60681 (FKBP10)	0.25	0.26	0.25	0.48	0.24	0.20	0.24	0.28	0.26	0.26	0.19	0.18	0.33	0.33	0.20	0.20	1.00	0.31	0.05	0.15	0.15	0.26	0.23	0.25	0.23	0.26	0.33	0.18	0.20	0.18	0.15	0.23	0.25	0.33	0.33	0.23	0.26	0.33	0.08	0.23	0.28	0.23	0.23	0.26
121340 (SP7)	0.49	0.46	0.49	0.54	0.46	0.36	0.42	0.31	0.48	0.53	0.10	0.21	0.69	0.69	0.36	0.30	0.31	1.00	0.05	0.26	0.18	0.50	0.34	0.50	0.41	0.50	0.85	0.36	0.17	0.10	0.19	0.41	0.42	0.69	0.69	0.12	0.51	0.49	0.10	0.47	0.33	0.41	0.39	0.46
55151 (TMEM38B)	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.04	0.07	0.07	0.07	0.07	0.05	0.05	0.05	1.00	0.38	0.11	0.06	0.05	0.06	0.06	0.06	0.06	0.04	0.04	0.04	0.05	0.05	0.06	0.07	0.07	0.05	0.06	0.05	0.03	0.05	0.05	0.36	0.06	0.06
7439 (BEST1)	0.50	0.32	0.58	0.42	0.40	0.32	0.49	0.27	0.45	0.52	0.10	0.21	0.82	0.82	0.44	0.30	0.15	0.26	0.38	1.00	0.23	0.42	0.32	0.42	0.33	0.42	0.44	0.42	0.15	0.08	0.15	0.47	0.36	0.82	0.82	0.12	0.40	0.24	0.10	0.56	0.35	0.46	0.35	0.43
5306 (PITPNA)	0.25	0.21	0.25	0.24	0.24	0.21	0.27	0.19	0.23	0.26	0.08	0.16	0.34	0.34	0.24	0.19	0.15	0.18	0.11	0.23	1.00	0.25	0.39	0.24	0.24	0.25	0.24	0.19	0.54	0.08	0.15	0.31	0.35	0.34	0.34	0.09	0.25	0.17	0.07	0.23	0.24	0.26	0.30	0.25
4641 (MYO1C)	0.72	0.58	0.71	0.67	0.70	0.57	0.69	0.49	0.69	0.79	0.13	0.26	1.00	1.00	0.58	0.49	0.26	0.50	0.06	0.42	0.25	1.00	0.53	0.61	0.69	0.85	0.67	0.51	0.22	0.12	0.25	0.63	0.68	1.00	1.00	0.15	0.78	0.46	0.12	0.84	0.46	0.68	0.63	0.77
4643 (MYO1E)	0.55	0.39	0.74	0.56	0.52	0.44	0.57	0.49	0.60	0.57	0.13	0.26	1.00	1.00	0.48	0.40	0.23	0.34	0.05	0.32	0.39	0.53	1.00	0.53	0.46	0.53	0.49	1.00	0.37	0.17	0.21	0.58	0.50	1.00	1.00	0.26	0.52	0.31	0.12	0.69	0.38	0.46	0.50	0.57
7531 (YWHAE)	0.62	0.46	0.72	0.67	0.60	0.54	0.62	0.51	0.63	0.63	0.13	0.26	1.00	1.00	0.55	0.55	0.25	0.50	0.06	0.42	0.24	0.61	0.53	1.00	0.58	0.61	0.62	0.53	0.24	0.11	0.23	0.60	0.58	1.00	1.00	0.15	0.65	0.48	0.22	0.69	0.46	0.57	0.59	0.63
5176 (SERPINF1)	0.66	0.46	0.71	0.61	0.61	0.48	0.61	0.39	0.62	0.72	0.13	0.26	1.00	1.00	0.54	0.41	0.23	0.41	0.06	0.33	0.24	0.69	0.46	0.58	1.00	0.69	0.59	0.51	0.21	0.12	0.23	0.59	0.58	1.00	1.00	0.15	0.68	0.41	1.00	0.69	0.40	0.55	0.63	0.65
285 (ANGPT2)	0.72	0.60	0.71	0.67	0.70	0.57	0.69	0.49	0.69	0.79	0.13	0.26	1.00	1.00	0.59	0.49	0.26	0.50	0.06	0.42	0.25	0.85	0.53	0.61	0.69	1.00	0.67	0.51	0.23	0.12	0.25	0.63	0.68	1.00	1.00	0.15	0.78	0.47	0.12	0.84	0.46	0.68	0.63	0.78
9852 (EPM2AIP1)	0.69	0.57	0.71	0.69	0.62	0.52	0.64	0.45	0.62	0.75	0.13	0.26	1.00	1.00	0.55	0.43	0.33	0.85	0.06	0.44	0.24	0.67	0.49	0.62	0.59	0.67	1.00	0.51	0.22	0.12	0.24	0.61	0.59	1.00	1.00	0.15	0.67	0.55	0.12	0.69	0.50	0.58	0.56	0.65
5358 (PLS3)	0.51	0.36	0.74	0.74	0.54	0.51	0.51	0.51	0.64	0.51	0.07	0.13	0.51	0.51	0.51	0.51	0.18	0.36	0.04	0.42	0.19	0.51	1.00	0.53	0.51	0.51	0.51	1.00	0.17	0.07	0.31	0.64	0.51	0.51	0.51	0.08	0.51	0.31	0.06	0.36	0.42	0.51	0.64	0.51
6121 (RPE65)	0.22	0.19	0.23	0.24	0.21	0.19	0.25	0.34	0.27	0.23	0.16	0.16	0.31	0.31	0.19	0.19	0.20	0.17	0.04	0.15	0.54	0.22	0.37	0.24	0.21	0.23	0.22	0.17	1.00	0.37	0.13	0.34	0.33	0.31	0.31	0.33	0.23	0.16	0.07	0.21	0.25	0.21	0.28	0.28
57104 (PNPLA2)	0.12	0.13	0.10	0.14	0.12	0.11	0.11	0.31	0.17	0.12	0.15	0.14	0.14	0.14	0.11	0.15	0.18	0.10	0.04	0.08	0.08	0.12	0.17	0.11	0.12	0.12	0.12	0.07	0.37	1.00	0.09	0.10	0.12	0.14	0.14	0.30	0.13	0.08	0.06	0.09	0.14	0.12	0.12	0.17
8578 (SCARF1)	0.25	0.22	0.43	0.28	0.25	0.54	0.24	0.18	0.24	0.26	0.09	0.18	0.36	0.36	0.42	0.18	0.15	0.19	0.05	0.15	0.15	0.25	0.21	0.23	0.23	0.25	0.24	0.31	0.13	0.09	1.00	0.33	0.24	0.36	0.36	0.10	0.25	0.17	0.08	0.24	0.21	0.22	0.25	0.24
7057 (THBS1)	0.64	0.43	0.87	0.66	0.66	0.56	0.69	0.53	0.63	0.66	0.13	0.26	1.00	1.00	0.57	0.50	0.23	0.41	0.05	0.47	0.31	0.63	0.58	0.60	0.59	0.63	0.61	0.64	0.34	0.10	0.33	1.00	0.70	1.00	1.00	0.15	0.62	0.37	0.12	0.69	0.52	0.59	0.71	0.67
3075 (CFH)	0.66	0.45	0.71	0.61	0.61	0.50	0.69	0.42	0.62	0.71	0.13	0.26	1.00	1.00	0.52	0.42	0.25	0.42	0.06	0.36	0.35	0.68	0.50	0.58	0.58	0.68	0.59	0.51	0.33	0.12	0.24	0.70	1.00	1.00	1.00	0.15	0.67	0.41	0.12	0.69	0.42	0.57	0.77	0.68
9315 (NREP)	1.00	0.69	0.71	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.13	0.26	1.00	1.00	1.00	1.00	0.33	0.69	0.07	0.82	0.34	1.00	1.00	1.00	1.00	1.00	1.00	0.51	0.31	0.14	0.36	1.00	1.00	1.00	1.00	0.15	1.00	0.60	0.12	0.69	0.82	1.00	1.00	1.00
51008 (ASCC1)	1.00	0.69	0.71	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.13	0.26	1.00	1.00	1.00	1.00	0.33	0.69	0.07	0.82	0.34	1.00	1.00	1.00	1.00	1.00	1.00	0.51	0.31	0.14	0.36	1.00	1.00	1.00	1.00	0.15	1.00	0.60	0.12	0.69	0.82	1.00	1.00	1.00
8492 (PRSS12)	0.15	0.18	0.11	0.23	0.15	0.15	0.18	0.83	1.00	0.15	0.16	0.15	0.15	0.15	0.15	0.18	0.23	0.12	0.05	0.12	0.09	0.15	0.26	0.15	0.15	0.15	0.15	0.08	0.33	0.30	0.10	0.15	0.15	0.15	0.15	1.00	0.15	0.09	0.07	0.10	0.20	0.15	0.15	0.83
51438 (MAGEC2)	0.72	0.50	0.71	0.67	0.68	0.55	0.63	0.46	0.66	0.80	0.13	0.26	1.00	1.00	0.54	0.44	0.26	0.51	0.06	0.40	0.25	0.78	0.52	0.65	0.68	0.78	0.67	0.51	0.23	0.13	0.25	0.62	0.67	1.00	1.00	0.15	1.00	0.48	0.12	0.69	0.45	0.67	0.62	0.72
64092 (SAMSN1)	0.43	0.39	0.43	0.56	0.41	0.33	0.37	0.28	0.39	0.48	0.08	0.16	0.60	0.60	0.32	0.26	0.33	0.49	0.05	0.24	0.17	0.46	0.31	0.48	0.41	0.47	0.55	0.31	0.16	0.08	0.17	0.37	0.41	0.60	0.60	0.09	0.48	1.00	0.07	0.40	0.31	0.41	0.38	0.49
284293 (HMSD)	0.12	0.15	0.09	0.12	0.12	0.12	0.15	0.12	0.12	0.12	0.06	0.12	0.12	0.12	0.42	0.22	0.08	0.10	0.03	0.10	0.07	0.12	0.12	0.22	1.00	0.12	0.12	0.06	0.07	0.06	0.08	0.12	0.12	0.12	0.12	0.07	0.12	0.07	1.00	0.08	0.12	0.12	0.42	0.12
84432 (PROK1)	0.69	0.86	0.49	0.69	0.69	0.69	0.70	0.69	0.84	0.69	0.09	0.18	0.69	0.69	0.86	0.70	0.23	0.47	0.05	0.56	0.23	0.84	0.69	0.69	0.69	0.84	0.69	0.36	0.21	0.09	0.24	0.69	0.69	0.69	0.69	0.10	0.69	0.40	0.08	1.00	0.56	0.69	0.69	0.84
6652 (SORD)	0.52	0.36	0.58	0.49	0.44	0.38	0.51	0.38	0.48	0.54	0.28	0.26	0.82	0.82	0.45	0.35	0.28	0.33	0.05	0.35	0.24	0.46	0.38	0.46	0.40	0.46	0.50	0.42	0.25	0.14	0.21	0.52	0.42	0.82	0.82	0.20	0.45	0.31	0.12	0.56	1.00	0.40	0.41	0.47
7780 (SLC30A2)	0.66	0.46	0.71	0.61	0.61	0.48	0.60	0.39	0.62	0.72	0.13	0.26	1.00	1.00	0.51	0.40	0.23	0.41	0.36	0.46	0.26	0.68	0.46	0.57	0.55	0.68	0.58	0.51	0.21	0.12	0.22	0.59	0.57	1.00	1.00	0.15	0.67	0.41	0.12	0.69	0.40	1.00	0.53	0.65
5118 (PCOLCE)	0.63	0.44	0.87	0.67	0.60	0.48	0.67	0.41	0.62	0.66	0.13	0.26	1.00	1.00	0.53	0.42	0.23	0.39	0.06	0.35	0.30	0.63	0.50	0.59	0.63	0.63	0.56	0.64	0.28	0.12	0.25	0.71	0.77	1.00	1.00	0.15	0.62	0.38	0.42	0.69	0.41	0.53	1.00	0.63
5327 (PLAT)	0.69	0.55	0.71	0.66	0.67	0.57	0.68	0.80	0.85	0.74	0.13	0.26	1.00	1.00	0.58	0.50	0.26	0.46	0.06	0.43	0.25	0.77	0.57	0.63	0.65	0.78	0.65	0.51	0.28	0.17	0.24	0.67	0.68	1.00	1.00	0.83	0.72	0.49	0.12	0.84	0.47	0.65	0.63	1.00

Association with High Altitude

Protein Official symbol	Source Organism	Tissue of Expression	Level of hypoxia	Altitude	Duration of experiment	Level of expression	Fold change	Experiment details	geographical location	ethnicity of the patients	Control group	Control (Fold change)	Reference (PMID)
SERPINF2	Human	Blood	-	3600 m	Native	downregulated	-	TMT-based proteomic analysis/LC-MS	Central Asia	Tibetans	-	High altitude native vs. low Lander	30908922

Association with TF

TF	TF Entrez	Gene	Gene Entrez	Type	PMID	Database
E2F6	1876	SERPINF2	5345	distal	22955619	TRANSFAC
TAL1	6886	SERPINF2	5345	distal	22955619	TRANSFAC
GABPA	2551	SERPINF2	5345	distal	22955619	TRANSFAC
JUND	3727	SERPINF2	5345	distal	22955619	TRANSFAC
EGR1	1958	SERPINF2	5345	distal	22955619	TRANSFAC
NFE2	4778	SERPINF2	5345	distal	22955619	TRANSFAC
CCNT2	905	SERPINF2	5345	distal	22955619	TRANSFAC
SPI1	6688	SERPINF2	5345	distal	22955619	TRANSFAC
NR2C2	7182	SERPINF2	5345	distal	22955619	TRANSFAC
YY1	7528	SERPINF2	5345	distal	22955619	TRANSFAC
MAFK	7975	SERPINF2	5345	distal	22955619	TRANSFAC
MAX	4149	SERPINF2	5345	distal	22955619	TRANSFAC
GATA2	2624	SERPINF2	5345	distal	22955619	TRANSFAC
TBP	6908	SERPINF2	5345	distal	22955619	TRANSFAC
REST	5978	SERPINF2	5345	distal	22955619	TRANSFAC
FOXA1	3169	SERPINF2	5345	proximal_filtered	22955619	TRANSFAC
FOXA2	3170	SERPINF2	5345	proximal_filtered	22955619	TRANSFAC

Association with miRNA

miRTarBase ID	miRNA	Species (miRNA)	Protein Official Symbol	Human Entrez ID	Species (Target Gene)	Experiments	Support Type	References (PMID)
MIRT437913	hsa-miR-224-5p	Homo sapiens	SERPINF2	5345	Homo sapiens	qRT-PCR//Western blot	Functional MTI	24785373
MIRT662465	hsa-miR-6833-3p	Homo sapiens	SERPINF2	5345	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT662472	hsa-miR-6832-3p	Homo sapiens	SERPINF2	5345	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT662467	hsa-miR-3191-5p	Homo sapiens	SERPINF2	5345	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT662469	hsa-miR-204-5p	Homo sapiens	SERPINF2	5345	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT662464	hsa-miR-6809-3p	Homo sapiens	SERPINF2	5345	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT662468	hsa-miR-211-5p	Homo sapiens	SERPINF2	5345	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT662470	hsa-miR-4685-3p	Homo sapiens	SERPINF2	5345	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT662475	hsa-miR-4687-5p	Homo sapiens	SERPINF2	5345	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT662474	hsa-miR-6887-3p	Homo sapiens	SERPINF2	5345	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT662471	hsa-miR-4287	Homo sapiens	SERPINF2	5345	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT662466	hsa-miR-4768-5p	Homo sapiens	SERPINF2	5345	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT662473	hsa-miR-6892-3p	Homo sapiens	SERPINF2	5345	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327

Gene Ontology

ID	GO ID	GO Term	GO Type
5345	GO:0010757	negative regulation of plasminogen activation	GOTERM_BP_DIRECT
5345	GO:0002576	platelet degranulation	GOTERM_BP_DIRECT
5345	GO:0010951	negative regulation of endopeptidase activity	GOTERM_BP_DIRECT
5345	GO:0006953	acute-phase response	GOTERM_BP_DIRECT
5345	GO:0070374	positive regulation of ERK1 and ERK2 cascade	GOTERM_BP_DIRECT
5345	GO:0009986	cell surface	GOTERM_CC_DIRECT
5345	GO:0031093	platelet alpha granule lumen	GOTERM_CC_DIRECT
5345	GO:0048661	positive regulation of smooth muscle cell proliferation	GOTERM_BP_DIRECT
5345	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin	GOTERM_BP_DIRECT
5345	GO:0051918	negative regulation of fibrinolysis	GOTERM_BP_DIRECT
5345	GO:0005577	fibrinogen complex	GOTERM_CC_DIRECT
5345	GO:0070062	extracellular exosome	GOTERM_CC_DIRECT
5345	GO:0071636	positive regulation of transforming growth factor beta production	GOTERM_BP_DIRECT
5345	GO:0046330	positive regulation of JNK cascade	GOTERM_BP_DIRECT
5345	GO:0005576	extracellular region	GOTERM_CC_DIRECT
5345	GO:0004867	serine-type endopeptidase inhibitor activity	GOTERM_MF_DIRECT
5345	GO:0005515	protein binding	GOTERM_MF_DIRECT
5345	GO:0048514	blood vessel morphogenesis	GOTERM_BP_DIRECT
5345	GO:0004866	endopeptidase inhibitor activity	GOTERM_MF_DIRECT
5345	GO:0045597	positive regulation of cell differentiation	GOTERM_BP_DIRECT
5345	GO:0072562	blood microparticle	GOTERM_CC_DIRECT
5345	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	GOTERM_BP_DIRECT
5345	GO:0051496	positive regulation of stress fiber assembly	GOTERM_BP_DIRECT
5345	GO:0002034	regulation of blood vessel size by renin-angiotensin	GOTERM_BP_DIRECT
5345	GO:0010033	response to organic substance	GOTERM_BP_DIRECT
5345	GO:0030199	collagen fibril organization	GOTERM_BP_DIRECT
5345	GO:0032967	positive regulation of collagen biosynthetic process	GOTERM_BP_DIRECT
5345	GO:0002020	protease binding	GOTERM_MF_DIRECT
5345	GO:0042803	protein homodimerization activity	GOTERM_MF_DIRECT
5345	GO:0005615	extracellular space	GOTERM_CC_DIRECT
5345	GO:0042730	fibrinolysis	GOTERM_BP_DIRECT

Pathways

Human Entrez ID	KEGG ID	KEGG Term
5345	hsa04610	Complement and coagulation cascades

Association with Disease

Protein Official Symbol	Human Entrez ID	Disease Name	Disease Id	Disease Semantic Type	Semantic score	DSI	DPI	Disease Type
SERPINF2	5345	Anti-plasmin deficiency, congenital	C3489734	Disease or Syndrome	0.3	0.681	0.552	disease
SERPINF2	5345	ALPHA-2-PLASMIN INHIBITOR DEFICIENCY	C2752081	Disease or Syndrome	0.9	0.681	0.552	disease

Association with Drug

Protein Official Symbol	Human Entrez ID	drug_claim_primary_name	drug_name	drug_chembl_id	interaction_types