| Protein Official symbol | UMOD |
| Aliases | UMOD |
| Chromosomal Location | 16 |
| Length | 640 |
| Uniprot ID | P07911 |
| EC number | None |
| Protein family Information(Pfam) | PF12947;PF07645;PF00100; |
| PDB id | 4WRN; |
| InterPro ID | IPR001881;IPR013032;IPR000742;IPR000152;IPR018097;IPR024731;IPR009030;IPR001507;IPR017977; |
| dbSNP | rs121917768 rs28934584 rs780462125 rs1555487621 rs121917769 rs121917770 rs28934582 rs28934583 rs28934583 rs1447458978 rs886043751 rs121917771 rs121917772 rs121917773 rs1555487318 rs55772253 |
| Protein 1 | Protein 2 | Combine Score |
|---|---|---|
| UMOD | B4GALNT2 | 0.947 |
| # | 7369 (UMOD) | 124872 (B4GALNT2) |
|---|---|---|
| 7369 (UMOD) | 1.00 | 0.08 |
| 124872 (B4GALNT2) | 0.08 | 1.00 |
| Protein Official symbol | Source Organism | Tissue of Expression | Level of hypoxia | Altitude | Duration of experiment | Level of expression | Fold change | Experiment details | geographical location | ethnicity of the patients | Control group | Control (Fold change) | Reference (PMID) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UMOD | Human | Urine | - | 5400 m | 5 day | downregulated | - | MALDI-TOF/TOF of petides | Himalayas | Italians | - | Males and females residing < 500 m above sea level | 22146998 |
| UMOD | Human | Urine | - | 5400 m | 5 day | downregulated | - | MALDI-TOF/TOF of petides | Himalayas | Italians | - | Males and females residing < 500 m above sea level | 22146999 |
| UMOD | Human | Urine | - | 3500 m | 3 day | downregulated | - | MALDI-TOF/TOF of petides | Himalayas | Italians | - | Males and females residing < 500 m above sea level | 22146999 |
| UMOD | Human | Urine | - | 3500 m | 3 day | downregulated | - | MALDI-TOF/TOF of petides | Himalayas | Italians | - | Males and females residing < 500 m above sea level | 22146998 |
| miRTarBase ID | miRNA | Species (miRNA) | Protein Official Symbol | Human Entrez ID | Species (Target Gene) | Experiments | Support Type | References (PMID) |
|---|
| ID | GO ID | GO Term | GO Type |
|---|---|---|---|
| 7369 | GO:0072218 | metanephric ascending thin limb development | GOTERM_BP_DIRECT |
| 7369 | GO:0007159 | leukocyte cell-cell adhesion | GOTERM_BP_DIRECT |
| 7369 | GO:0031225 | anchored component of membrane | GOTERM_CC_DIRECT |
| 7369 | GO:0072233 | metanephric thick ascending limb development | GOTERM_BP_DIRECT |
| 7369 | GO:0072221 | metanephric distal convoluted tubule development | GOTERM_BP_DIRECT |
| 7369 | GO:0007588 | excretion | GOTERM_BP_DIRECT |
| 7369 | GO:0005509 | calcium ion binding | GOTERM_MF_DIRECT |
| 7369 | GO:0006968 | cellular defense response | GOTERM_BP_DIRECT |
| 7369 | GO:0016021 | integral component of membrane | GOTERM_CC_DIRECT |
| 7369 | GO:0016324 | apical plasma membrane | GOTERM_CC_DIRECT |
| 7369 | GO:0070062 | extracellular exosome | GOTERM_CC_DIRECT |
| 7369 | GO:0008285 | negative regulation of cell proliferation | GOTERM_BP_DIRECT |
| 7369 | GO:0019898 | extrinsic component of membrane | GOTERM_CC_DIRECT |
| 7369 | GO:0048878 | chemical homeostasis | GOTERM_BP_DIRECT |
| 7369 | GO:1990266 | neutrophil migration | GOTERM_BP_DIRECT |
| 7369 | GO:0000922 | spindle pole | GOTERM_CC_DIRECT |
| 7369 | GO:0072372 | primary cilium | GOTERM_CC_DIRECT |
| 7369 | GO:0005578 | proteinaceous extracellular matrix | GOTERM_CC_DIRECT |
| 7369 | GO:0016323 | basolateral plasma membrane | GOTERM_CC_DIRECT |
| 7369 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules | GOTERM_BP_DIRECT |
| 7369 | GO:2000021 | regulation of ion homeostasis | GOTERM_BP_DIRECT |
| 7369 | GO:0019864 | calcium channel inhibitor activity | GOTERM_MF_DIRECT |
| 7369 | GO:0005929 | cilium | GOTERM_CC_DIRECT |
| 7369 | GO:0005201 | extracellular matrix structural constituent | GOTERM_MF_DIRECT |
| 7369 | GO:0005576 | extracellular region | GOTERM_CC_DIRECT |
| 7369 | GO:0060170 | ciliary membrane | GOTERM_CC_DIRECT |
| Human Entrez ID | KEGG ID | KEGG Term |
|---|
| Protein Official Symbol | Human Entrez ID | Disease Name | Disease Id | Disease Semantic Type | Semantic score | DSI | DPI | Disease Type |
|---|---|---|---|---|---|---|---|---|
| UMOD | 7369 | Hypertensive disease | C0020538 | Disease or Syndrome | 0.5 | 0.6 | 0.517 | group |
| UMOD | 7369 | Kidney Diseases | C0022658 | Disease or Syndrome | 0.7 | 0.6 | 0.517 | group |
| UMOD | 7369 | Familial juvenile gout | C0268113 | Disease or Syndrome | 1 | 0.6 | 0.517 | disease |
| UMOD | 7369 | Medullary Cystic Kidney Disease Type 2 | C1859040 | Disease or Syndrome | 0.78 | 0.6 | 0.517 | disease |
| UMOD | 7369 | Glomerulocystic Kidney Disease with Hyperuricemia and Isosthenuria | C1835934 | Disease or Syndrome | 0.6 | 0.6 | 0.517 | disease |
| UMOD | 7369 | Cystic Kidney Diseases | C1691228 | Disease or Syndrome | 0.34 | 0.6 | 0.517 | group |
| UMOD | 7369 | Cakut | C1968949 | Disease or Syndrome | 0.3 | 0.6 | 0.517 | disease |
| UMOD | 7369 | Ciliopathies | C4277690 | Congenital Abnormality | 0.3 | 0.6 | 0.517 | group |