Serum deprivation-response protein

AltitudeomicsDB
Protein Official symbol SDPR
Aliases CAVIN2 SDPR
Chromosomal Location 2
Length 425
Uniprot ID O95810
EC number None
Protein family Information(Pfam) PF15237;
PDB id None
InterPro ID IPR033298;IPR026752;
dbSNP rs35012125

Protein Protein Interaction

0%
Download Tab separated file
AltitudeomicsDB
Protein 1 Protein 2 Combine Score
SDPR DHRS1 0.904
Gene Ontology Semantic Similarity
Download Tab separated file
# 8436 (SDPR) 115817 (DHRS1)
8436 (SDPR) 1.00 1.00
115817 (DHRS1) 1.00 1.00
Association with High Altitude
Protein Official symbol Source Organism Tissue of Expression Level of hypoxia Altitude Duration of experiment Level of expression Fold change Experiment details geographical location ethnicity of the patients Control group Control (Fold change) Reference (PMID)
SDPR Human Blood - 3600 m Native upregulated - TMT-based proteomic analysis/LC-MS Central Asia Tibetans - High altitude native vs. low Lander 30908922
Association with TF
TF TF Entrez Gene Gene Entrez Type PMID Database
JUN 3725 SDPR 8436 proximal_filtered 22955619 TRANSFAC
Association with miRNA
miRTarBase ID miRNA Species (miRNA) Protein Official Symbol Human Entrez ID Species (Target Gene) Experiments Support Type References (PMID)
MIRT023867 hsa-miR-1-3p Homo sapiens SDPR 8436 Homo sapiens Microarray Functional MTI (Weak) 18668037
Gene Ontology
ID GO ID GO Term GO Type
8436 GO:0005737 cytoplasm GOTERM_CC_DIRECT
8436 GO:0005080 protein kinase C binding GOTERM_MF_DIRECT
8436 GO:0005515 protein binding GOTERM_MF_DIRECT
8436 GO:0045121 membrane raft GOTERM_CC_DIRECT
8436 GO:0005543 phospholipid binding GOTERM_MF_DIRECT
8436 GO:0005901 caveola GOTERM_CC_DIRECT
8436 GO:0001786 G-protein coupled receptor binding GOTERM_MF_DIRECT
8436 GO:0005829 cytosol GOTERM_CC_DIRECT
Pathways
Human Entrez ID KEGG ID KEGG Term
Association with Disease
Protein Official Symbol Human Entrez ID Disease Name Disease Id Disease Semantic Type Semantic score DSI DPI Disease Type
CAVIN2 8436 Aganglionosis, Rectosigmoid Colon C1257840 Congenital Abnormality 0.3 0.707 0.345 disease
CAVIN2 8436 Hirschsprung Disease C0019569 Disease or Syndrome 0.31 0.707 0.345 disease
CAVIN2 8436 Congenital Intestinal Aganglionosis C3661523 Disease or Syndrome 0.3 0.707 0.345 disease
CAVIN2 8436 Aganglionosis, Colonic C0085758 Congenital Abnormality 0.3 0.707 0.345 disease
Association with Drug
Protein Official Symbol Human Entrez ID drug_claim_primary_name drug_name drug_chembl_id interaction_types