Tyrosylprotein sulfotransferase 1

AltitudeomicsDB
Protein Official symbol TPST1
Aliases TPST1
Chromosomal Location 7
Length 370
Uniprot ID O60507
EC number 2.8.2.20
Protein family Information(Pfam) None
PDB id 5WRI;5WRJ;
InterPro ID IPR027417;IPR026634;
dbSNP None

Protein Protein Interaction

0%
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AltitudeomicsDB
Protein 1 Protein 2 Combine Score
PODXL2 TPST1 0.904
Gene Ontology Semantic Similarity
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# 50512 (PODXL2) 8460 (TPST1)
50512 (PODXL2) 1.00 0.42
8460 (TPST1) 0.42 1.00
Association with High Altitude
Protein Official symbol Source Organism Tissue of Expression Level of hypoxia Altitude Duration of experiment Level of expression Fold change Experiment details geographical location ethnicity of the patients Control group Control (Fold change) Reference (PMID)
TPST1 Human Blood - 3650 m 48 hours downregulated 0.607 Microarray Himalayas Indians 1 HAPE Pateints Vs Normal http://medind.nic.in/iab/t12/i1/iabt12i1p1.pdf
Association with TF
TF TF Entrez Gene Gene Entrez Type PMID Database
EP300 2033 TPST1 8460 distal 22955619 TRANSFAC
PAX5 5079 TPST1 8460 proximal_filtered 22955619 TRANSFAC
Association with miRNA
miRTarBase ID miRNA Species (miRNA) Protein Official Symbol Human Entrez ID Species (Target Gene) Experiments Support Type References (PMID)
MIRT022966 hsa-miR-124-3p Homo sapiens TPST1 8460 Homo sapiens Microarray Functional MTI (Weak) 18668037
Gene Ontology
ID GO ID GO Term GO Type
8460 GO:0008476 alanine-glyoxylate transaminase activity GOTERM_MF_DIRECT
8460 GO:0005794 Golgi apparatus GOTERM_CC_DIRECT
8460 GO:0006954 inflammatory response GOTERM_BP_DIRECT
8460 GO:0000139 Golgi membrane GOTERM_CC_DIRECT
8460 GO:0016020 membrane GOTERM_CC_DIRECT
8460 GO:0006478 peptidyl-tyrosine sulfation GOTERM_BP_DIRECT
8460 GO:0016021 integral component of membrane GOTERM_CC_DIRECT
Pathways
Human Entrez ID KEGG ID KEGG Term
Association with Disease
Protein Official Symbol Human Entrez ID Disease Name Disease Id Disease Semantic Type Semantic score DSI DPI Disease Type
Association with Drug
Protein Official Symbol Human Entrez ID drug_claim_primary_name drug_name drug_chembl_id interaction_types