Acyl carrier protein

AltitudeomicsDB
Protein Official symbol ACPP
Aliases ACP3 ACPP
Chromosomal Location 3
Length 386.0
Uniprot ID P15309
EC number 3.1.3.2; 3.1.3.5
Protein family Information(Pfam) PF00328;
PDB id 1CVI;1ND5;1ND6;2HPA;2L3H;2L77;2L79;2MG0;3PPD;
InterPro ID IPR033379;IPR000560;IPR029033;
dbSNP rs17850347 rs17856254 rs17856253 rs17851392 rs17850198

Protein Protein Interaction

0%
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AltitudeomicsDB
Protein 1 Protein 2 Combine Score
VAPA LAMP1 0.935
LAMP1 ACPP 0.933
LAMP1 LAMTOR1 0.931
DDOST VAPA 0.917
PIGR LAMP1 0.914
VNN1 PIGR 0.913
PIGR ACPP 0.909
DDOST LAMP1 0.908
PRCP ACPP 0.906
VNN1 NFAM1 0.906
CPNE3 VNN1 0.906
LRMP NFAM1 0.906
ACPP LAMTOR1 0.904
DDOST ACPP 0.904
LRMP ACPP 0.904
VNN1 ACPP 0.904
DDOST VNN1 0.904
DDOST LAMTOR1 0.904
VNN1 LRMP 0.904
NFAM1 ACPP 0.903
VAPA ACPP 0.903
CPNE3 ACPP 0.903
LRMP LAMP1 0.902
PRCP VNN1 0.902
PRCP LAMP1 0.902
NFAM1 LAMP1 0.902
DDOST PRCP 0.902
PRCP LRMP 0.901
CPNE3 PRCP 0.901
LRMP LAMTOR1 0.901
LRMP VAPA 0.9
CPNE3 VAPA 0.9
NFAM1 LAMTOR1 0.9
PRCP VAPA 0.9
VNN1 LAMTOR1 0.9
PRCP LAMTOR1 0.9
VAPA LAMTOR1 0.9
VNN1 LAMP1 0.9
VNN1 VAPA 0.9
CPNE3 LRMP 0.9
PIGR LAMTOR1 0.9
PIGR VAPA 0.9
DDOST NFAM1 0.9
CPNE3 LAMTOR1 0.9
DDOST LRMP 0.9
PIGR LRMP 0.9
CPNE3 PIGR 0.9
CPNE3 DDOST 0.9
VAPA NFAM1 0.9
CPNE3 LAMP1 0.9
PRCP NFAM1 0.9
DDOST PIGR 0.9
PIGR NFAM1 0.9
PRCP PIGR 0.9
CPNE3 NFAM1 0.9
Gene Ontology Semantic Similarity
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# 3916 (LAMP1) 55 (ACPP) 55004 (LAMTOR1) 9218 (VAPA) 5284 (PIGR) 150372 (NFAM1) 8876 (VNN1) 5547 (PRCP) 1650 (DDOST) 8895 (CPNE3)
3916 (LAMP1) 1.00 0.49 0.78 0.78 0.13 0.16 0.16 0.61 0.62 0.60
55 (ACPP) 0.49 1.00 0.48 0.54 0.13 0.16 0.34 0.45 0.42 0.46
55004 (LAMTOR1) 0.78 0.48 1.00 0.71 0.13 0.16 0.16 0.56 0.57 0.57
9218 (VAPA) 0.78 0.54 0.71 1.00 0.13 0.16 0.16 0.63 0.63 0.61
5284 (PIGR) 0.13 0.13 0.13 0.13 1.00 0.82 0.08 0.13 0.13 0.17
150372 (NFAM1) 0.16 0.16 0.16 0.16 0.82 1.00 0.10 0.16 0.16 0.20
8876 (VNN1) 0.16 0.34 0.16 0.16 0.08 0.10 1.00 0.26 0.20 0.21
5547 (PRCP) 0.61 0.45 0.56 0.63 0.13 0.16 0.26 1.00 0.43 0.48
1650 (DDOST) 0.62 0.42 0.57 0.63 0.13 0.16 0.20 0.43 1.00 0.51
8895 (CPNE3) 0.60 0.46 0.57 0.61 0.17 0.20 0.21 0.48 0.51 1.00
Association with High Altitude
Protein Official symbol Source Organism Tissue of Expression Level of hypoxia Altitude Duration of experiment Level of expression Fold change Experiment details geographical location ethnicity of the patients Control group Control (Fold change) Reference (PMID)
ACPP Rat Left brain cortices 300hPa 9144 m 1 hour downregulated 0.81±0.0 TMT labeled LTQ orbitrap Southwestern europe Male wistar rats 1 Adult male Wistar rats weighing 350 g 28697276
Association with TF
TF TF Entrez Gene Gene Entrez Type PMID Database
Association with miRNA
miRTarBase ID miRNA Species (miRNA) Protein Official Symbol Human Entrez ID Species (Target Gene) Experiments Support Type References (PMID)
MIRT032233 hsa-let-7b-5p Homo sapiens ACPP 55 Homo sapiens Proteomics Functional MTI (Weak) 18668040
MIRT441291 hsa-miR-539-5p Homo sapiens ACPP 55 Homo sapiens HITS-CLIP Functional MTI (Weak) 24374217
MIRT443462 hsa-miR-6803-5p Homo sapiens ACPP 55 Homo sapiens PAR-CLIP Functional MTI (Weak) 22100165
MIRT443463 hsa-miR-6751-5p Homo sapiens ACPP 55 Homo sapiens PAR-CLIP Functional MTI (Weak) 22100165
MIRT443464 hsa-miR-548s Homo sapiens ACPP 55 Homo sapiens PAR-CLIP Functional MTI (Weak) 22100165
MIRT443465 hsa-miR-6881-5p Homo sapiens ACPP 55 Homo sapiens PAR-CLIP Functional MTI (Weak) 22100165
MIRT443466 hsa-miR-7110-5p Homo sapiens ACPP 55 Homo sapiens PAR-CLIP Functional MTI (Weak) 22100165
MIRT443467 hsa-miR-6752-5p Homo sapiens ACPP 55 Homo sapiens PAR-CLIP Functional MTI (Weak) 22100165
MIRT443468 hsa-miR-6842-5p Homo sapiens ACPP 55 Homo sapiens PAR-CLIP Functional MTI (Weak) 22100165
MIRT443469 hsa-miR-6835-5p Homo sapiens ACPP 55 Homo sapiens PAR-CLIP Functional MTI (Weak) 22100165
MIRT443470 hsa-miR-4731-5p Homo sapiens ACPP 55 Homo sapiens PAR-CLIP Functional MTI (Weak) 22100165
MIRT443471 hsa-miR-3926 Homo sapiens ACPP 55 Homo sapiens PAR-CLIP Functional MTI (Weak) 22100165
MIRT443472 hsa-miR-637 Homo sapiens ACPP 55 Homo sapiens PAR-CLIP Functional MTI (Weak) 22100165
MIRT443473 hsa-miR-3973 Homo sapiens ACPP 55 Homo sapiens PAR-CLIP Functional MTI (Weak) 22100165
MIRT443474 hsa-miR-5197-5p Homo sapiens ACPP 55 Homo sapiens PAR-CLIP Functional MTI (Weak) 22100165
MIRT443475 hsa-miR-320e Homo sapiens ACPP 55 Homo sapiens PAR-CLIP Functional MTI (Weak) 22100165
MIRT443476 hsa-miR-548l Homo sapiens ACPP 55 Homo sapiens PAR-CLIP Functional MTI (Weak) 22100165
MIRT443477 hsa-miR-4429 Homo sapiens ACPP 55 Homo sapiens PAR-CLIP Functional MTI (Weak) 22100165
MIRT443478 hsa-miR-320d Homo sapiens ACPP 55 Homo sapiens PAR-CLIP Functional MTI (Weak) 22100165
MIRT443479 hsa-miR-320c Homo sapiens ACPP 55 Homo sapiens PAR-CLIP Functional MTI (Weak) 22100165
MIRT443480 hsa-miR-320b Homo sapiens ACPP 55 Homo sapiens PAR-CLIP Functional MTI (Weak) 22100165
MIRT443481 hsa-miR-320a Homo sapiens ACPP 55 Homo sapiens PAR-CLIP Functional MTI (Weak) 22100165
MIRT785110 hsa-miR-3672 Homo sapiens ACPP 55 Homo sapiens HITS-CLIP Functional MTI (Weak) 27418678
MIRT785938 hsa-miR-4461 Homo sapiens ACPP 55 Homo sapiens HITS-CLIP Functional MTI (Weak) 27418678
MIRT786098 hsa-miR-4524a-3p Homo sapiens ACPP 55 Homo sapiens HITS-CLIP Functional MTI (Weak) 27418678
MIRT786146 hsa-miR-4524b-3p Homo sapiens ACPP 55 Homo sapiens HITS-CLIP Functional MTI (Weak) 27418678
MIRT789115 hsa-miR-6864-3p Homo sapiens ACPP 55 Homo sapiens HITS-CLIP Functional MTI (Weak) 27418678
Gene Ontology
ID GO ID GO Term GO Type
Pathways
Human Entrez ID KEGG ID KEGG Term
Association with Disease
Protein Official Symbol Human Entrez ID Disease Name Disease Id Disease Semantic Type Semantic score DSI DPI Disease Type
ACPP 55 Juvenile-Onset Still Disease C0087031 Disease or Syndrome 0.3 0.63 0.517 disease
ACPP 55 Juvenile arthritis C3495559 Disease or Syndrome 0.3 0.63 0.517 disease
ACPP 55 Juvenile psoriatic arthritis C3714758 Disease or Syndrome 0.3 0.63 0.517 disease
Association with Drug
Protein Official Symbol Human Entrez ID drug_claim_primary_name drug_name drug_chembl_id interaction_types
ACPP 55 MVA-BN None None None
ACPP 55 MVA-BN None None None
ACPP 55 MVA-BN None None None