3,2-trans-Enoyl-CoA isomerase, mitochondrial

AltitudeomicsDB
Protein Official symbol ECI1
Aliases ECI1 DCI
Chromosomal Location 16
Length 302
Uniprot ID P42126
EC number 5.3.3.8
Protein family Information(Pfam) PF00378;
PDB id 1SG4;
InterPro ID IPR029045;IPR018376;IPR001753;
dbSNP None

Protein Protein Interaction

0%
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AltitudeomicsDB
Protein 1 Protein 2 Combine Score
ECI2 ECI1 0.993
ECHS1 ECI1 0.959
Gene Ontology Semantic Similarity
Download Tab separated file
# 10455 (ECI2) 1892 (ECHS1) 1632 (ECI1)
10455 (ECI2) 1.00 0.51 0.62
1892 (ECHS1) 0.51 1.00 0.54
1632 (ECI1) 0.62 0.54 1.00
Association with High Altitude
Protein Official symbol Source Organism Tissue of Expression Level of hypoxia Altitude Duration of experiment Level of expression Fold change Experiment details geographical location ethnicity of the patients Control group Control (Fold change) Reference (PMID)
ECI1 Human Skeletal muscle - 4559 m 9 day downregulated -1.11 2-DIGE Southern Europe Italians 1 Fasting control subjects at laboratory in Copenhagen with no caffeine intake 18937252
Association with TF
TF TF Entrez Gene Gene Entrez Type PMID Database
Association with miRNA
miRTarBase ID miRNA Species (miRNA) Protein Official Symbol Human Entrez ID Species (Target Gene) Experiments Support Type References (PMID)
MIRT020571 hsa-miR-155-5p Homo sapiens ECI1 1632 Homo sapiens Proteomics Functional MTI (Weak) 18668040
MIRT050587 hsa-miR-20a-5p Homo sapiens ECI1 1632 Homo sapiens CLASH Functional MTI (Weak) 23622248
Gene Ontology
ID GO ID GO Term GO Type
1632 GO:0016860 isomerase activity GOTERM_MF_DIRECT
1632 GO:0070062 extracellular exosome GOTERM_CC_DIRECT
1632 GO:0003824 catalytic activity GOTERM_MF_DIRECT
1632 GO:0004165 cytochrome-c oxidase activity GOTERM_MF_DIRECT
1632 GO:0005759 mitochondrial matrix GOTERM_CC_DIRECT
1632 GO:0005739 mitochondrion GOTERM_CC_DIRECT
1632 GO:0006635 fatty acid beta-oxidation GOTERM_BP_DIRECT
1632 GO:0008152 metabolic process GOTERM_BP_DIRECT
1632 GO:0005743 mitochondrial inner membrane GOTERM_CC_DIRECT
Pathways
Human Entrez ID KEGG ID KEGG Term
1632 hsa00071 Fatty acid degradation
Association with Disease
Protein Official Symbol Human Entrez ID Disease Name Disease Id Disease Semantic Type Semantic score DSI DPI Disease Type
Association with Drug
Protein Official Symbol Human Entrez ID drug_claim_primary_name drug_name drug_chembl_id interaction_types