ALTITUDEOMICSDB

Ephexin-1

AltitudeomicsDB

Protein Official symbol	NGEF
Aliases	NGEF
Chromosomal Location	:2
Length	710
Uniprot ID	Q8N5V2
EC number	None
Protein family Information(Pfam)	PF00169;PF00621;PF00018;
PDB id	None
InterPro ID	IPR035899;IPR000219;IPR035635;IPR011993;IPR001849;IPR036028;IPR001452;
dbSNP	rs2271703 rs4973588

Protein Protein Interaction

Download Tab separated file

AltitudeomicsDB

Protein 1	Protein 2	Combine Score
EFNA1	EPHA2	0.999
YES1	FYN	0.999
SRC	FYN	0.998
EFNA1	EPHA1	0.997
EFNA1	EPHA4	0.996
YES1	SRC	0.995
EPHA6	EFNA1	0.995
EFNA1	EPHA8	0.995
EPHB1	EFNA1	0.995
EPHA7	EFNA1	0.995
EFNA1	EPHA3	0.995
EPHA5	EFNA1	0.995
EPHB2	EFNA1	0.993
EFNA1	EPHB4	0.993
EPHB6	EFNA1	0.992
EFNA1	EPHB3	0.992
EPHA4	NGEF	0.989
CDC42	SRC	0.988
EPHA2	EPHA1	0.986
FGR	SRC	0.986
RHOA	RHOC	0.985
RAC3	RAC2	0.985
RAC1	RAC3	0.982
YES1	FGR	0.981
RHOA	SRC	0.98
FGR	FYN	0.98
CDC42	RHOC	0.976
RHOB	NGEF	0.976
RHOA	NGEF	0.972
CDC42	NGEF	0.972
HCK	FGR	0.971
CDC42	LCK	0.969
CDC42	FYN	0.968
RHOA	FYN	0.967
RHOA	EPHA3	0.966
RAC1	NGEF	0.965
CDC42	RAC2	0.965
SRC	RAC1	0.964
EPHA1	NGEF	0.962
SRC	NGEF	0.961
EFNA1	NGEF	0.958
RHOA	EPHA1	0.955
RHOA	EPHA4	0.955
CDC42	EPHB2	0.955
YES1	CDC42	0.953
EPHA3	NGEF	0.953
RHOA	EPHA2	0.953
EPHB2	SRC	0.953
RHOG	NGEF	0.952
EPHA2	NGEF	0.952
FYN	EPHA4	0.951
RHOD	NGEF	0.951
SRC	EFNA1	0.951
RAC1	FYN	0.95
RAC1	RHOC	0.949
CDC42	EPHB3	0.947
RAC3	RHOC	0.947
YES1	RHOA	0.947
RAC3	NGEF	0.946
RHOBTB2	RHOT2	0.945
RHOT1	RHOBTB1	0.945
RHOBTB2	RHOT1	0.945
RHOA	EFNA1	0.945
LYN	RHOA	0.944
FYN	EPHB3	0.944
RHOA	LCK	0.944
RHOA	EPHA7	0.944
RHOBTB1	RHOT2	0.943
NGEF	RHOV	0.942
RHOBTB2	NGEF	0.942
RHOBTB1	NGEF	0.942
RAC1	RHOB	0.942
RHOU	NGEF	0.941
EPHA5	RHOA	0.941
SRC	EPHA4	0.941
SRC	EPHA3	0.941
NGEF	RHOQ	0.94
YES1	EPHB2	0.94
RHOF	NGEF	0.94
RHOJ	NGEF	0.94
NGEF	RAC2	0.94
RAC1	LCK	0.94
EPHB6	EPHB4	0.939
EPHB2	RAC1	0.939
FYN	EPHA3	0.939
RHOH	NGEF	0.939
RHOA	CDC42	0.939
RHOA	EPHA6	0.938
RHOC	NGEF	0.938
EFNA1	FYN	0.938
SRC	RAC2	0.938
HCK	SRC	0.938
EPHB6	EPHB1	0.937
LYN	LCK	0.937
CDC42	RHOJ	0.937
LYN	SRC	0.936
EPHA7	EPHA2	0.935
CDC42	RAC3	0.934
LYN	RAC1	0.934
EPHA7	EPHA3	0.933
EPHB1	RAC1	0.933
EPHA2	RAC1	0.93
EPHA2	EPHA4	0.93
EPHB2	EPHA4	0.929
RHOC	RAC2	0.929
YES1	RAC1	0.928
RAC1	EPHB3	0.928
HCK	LYN	0.928
FYN	NGEF	0.927
EPHB6	RAC1	0.926
EPHB4	RAC1	0.926
EFNA1	RAC1	0.926
RHOA	RAC2	0.925
EFNA1	LCK	0.925
SRC	RAC3	0.924
LYN	EFNA1	0.923
RHOA	RAC1	0.923
EPHB1	SRC	0.922
SRC	EPHA2	0.922
EPHA2	EPHB4	0.921
RHOA	RAC3	0.92
HCK	NGEF	0.92
RHOB	RAC2	0.92
CDC42	RHOB	0.92
RHOT1	RHOT2	0.919
RHOG	RAC2	0.919
FGR	EFNA1	0.919
LYN	FGR	0.918
RAC3	RHOB	0.918
RHOBTB2	RHOF	0.917
EPHA7	EPHA4	0.917
HCK	EFNA1	0.917
YES1	EFNA1	0.917
EFNA1	BLK	0.917
RHOT2	NGEF	0.917
EPHB1	FYN	0.916
EPHB2	FYN	0.916
RHOH	RHOT1	0.916
EPHB2	EPHA2	0.916
RHOBTB1	RHOF	0.916
RHOT1	NGEF	0.916
SRC	EPHA1	0.915
SRC	EPHA7	0.915
RHOT1	RAC2	0.915
RHOT1	RHOF	0.915
EPHA2	EPHB3	0.915
EPHA5	SRC	0.915
RHOT1	RHOQ	0.915
EPHA6	EPHA7	0.915
YES1	EPHB1	0.914
EPHA5	EPHA6	0.914
EPHB4	FYN	0.914
RHOH	RAC2	0.914
LCK	BLK	0.914
RHOT1	RHOG	0.914
RHOH	RHOBTB1	0.914
YES1	EPHA2	0.914
EPHB1	NGEF	0.913
CDC42	RHOT1	0.913
RHOU	RHOBTB1	0.913
RHOH	RHOF	0.913
RHOT1	RHOC	0.913
RHOBTB2	RHOU	0.913
RHOT1	RAC1	0.913
EPHB1	EPHA2	0.913
RHOD	RHOV	0.913
EPHA7	FYN	0.913
RHOBTB2	RHOH	0.913
RHOT2	RHOD	0.912
EPHA5	FYN	0.912
EPHA5	EPHA2	0.912
RHOBTB1	RHOV	0.912
RHOH	RHOD	0.912
RHOH	RHOT2	0.912
EPHA2	FYN	0.912
RHOBTB1	RHOD	0.912
EPHA2	EPHA3	0.912
RHOH	RHOG	0.911
EPHA5	NGEF	0.911
YES1	EPHA7	0.911
YES1	EPHA3	0.911
EPHA5	YES1	0.911
RHOT2	RHOC	0.911
RHOBTB2	RHOD	0.911
FYN	EPHA1	0.911
RHOT1	RHOB	0.911
LCK	EPHA1	0.911
RHOG	RHOT2	0.91
RHOT1	RHOV	0.91
RHOT2	RHOQ	0.91
RHOU	RHOT1	0.91
YES1	EPHA4	0.91
RHOA	RHOT1	0.91
RHOT1	RHOJ	0.91
EPHA2	LCK	0.91
RHOT1	RHOD	0.91
RHOD	RHOC	0.91
RHOU	RHOT2	0.91
EPHA7	NGEF	0.91
EPHB4	EPHA1	0.91
YES1	NGEF	0.91
RHOT2	RHOJ	0.909
RHOT2	RHOF	0.909
EPHA6	SRC	0.909
RHOH	RHOQ	0.909
RHOF	RHOV	0.909
RHOBTB2	RHOV	0.909
EPHB6	EPHA1	0.909
RHOBTB1	RHOJ	0.909
EPHB2	NGEF	0.909
RHOJ	RHOD	0.909
RHOH	RAC1	0.909
RHOU	RHOD	0.909
EPHA5	EPHA7	0.909
RHOT2	RHOB	0.909
LYN	EPHA2	0.909
RHOH	RAC3	0.908
RHOBTB1	RHOB	0.908
EPHB3	NGEF	0.908
RHOH	RHOJ	0.908
EPHB2	EPHA1	0.908
RAC3	RHOV	0.908
EPHA6	EPHA8	0.908
RHOH	RHOU	0.908
RHOBTB2	CDC42	0.908
CDC42	RHOBTB1	0.908
NGEF	EPHA8	0.908
RHOH	RHOV	0.908
RHOF	RAC2	0.908
CDC42	RHOH	0.908
RHOBTB2	RHOJ	0.908
EPHB6	EPHA2	0.908
RHOH	RHOB	0.907
EPHA4	EPHA1	0.907
FGR	BLK	0.907
RHOT2	RHOV	0.907
RHOH	RHOC	0.907
RHOG	RHOF	0.907
LYN	NGEF	0.907
LYN	EPHA3	0.907
RHOT2	RAC2	0.907
EPHB6	FYN	0.907
HCK	EPHA2	0.907
RHOA	RHOH	0.907
RHOC	RHOV	0.907
EPHA5	EPHA4	0.907
FGR	EPHA2	0.907
EPHB1	EPHA4	0.907
LYN	EPHA4	0.907
RHOBTB2	RHOB	0.907
RHOT2	RAC3	0.907
EPHB3	EPHA1	0.907
CDC42	RHOT2	0.907
RHOA	RHOD	0.907
LYN	EPHA1	0.907
EPHA5	EPHB1	0.907
EPHA7	EPHA8	0.907
FYN	LCK	0.907
RHOG	RHOC	0.907
RHOA	RHOT2	0.907
RHOBTB2	RAC1	0.907
RHOJ	RHOV	0.907
RHOJ	RHOF	0.907
EPHB1	EPHA1	0.907
RAC1	RHOBTB1	0.907
RHOA	RHOBTB1	0.906
RHOJ	RHOC	0.906
LCK	EPHA3	0.906
HCK	BLK	0.906
EPHA3	EPHA1	0.906
SRC	LCK	0.906
EPHA6	EPHA4	0.906
RHOD	RHOQ	0.906
RAC1	RAC2	0.906
RHOG	RHOD	0.906
FGR	NGEF	0.906
RHOBTB1	RHOQ	0.906
RHOA	RHOG	0.906
RHOD	RAC3	0.906
FGR	LCK	0.906
CDC42	RAC1	0.906
CDC42	RHOG	0.906
EPHA1	EPHA8	0.906
RHOA	RHOV	0.906
RHOA	RHOJ	0.906
FGR	EPHA1	0.906
HCK	LCK	0.906
RAC1	RHOD	0.906
YES1	EPHA1	0.906
RHOF	RHOQ	0.906
RHOB	RHOV	0.906
RHOC	RHOQ	0.906
RHOU	RHOB	0.906
EPHB1	EPHA7	0.906
RHOU	RHOF	0.906
RHOBTB1	RHOC	0.906
RHOJ	RHOB	0.906
CDC42	RHOD	0.906
HCK	EPHA1	0.906
EPHB6	EPHA6	0.905
HCK	EPHA3	0.905
EPHB6	EPHA4	0.905
RHOG	RHOB	0.905
RHOBTB2	RHOQ	0.905
YES1	EPHA6	0.905
EPHB2	LCK	0.905
RHOG	RHOV	0.905
EPHA6	EPHA1	0.905
FGR	EPHA3	0.905
RHOBTB2	RHOG	0.905
RHOBTB1	RAC2	0.905
EPHB1	LCK	0.905
EPHA6	EPHA3	0.905
EPHB3	EPHA8	0.905
EPHA6	FYN	0.905
RHOU	RHOJ	0.905
EPHA7	EPHA1	0.905
RHOBTB2	RAC3	0.905
RHOB	RHOF	0.905
HCK	FYN	0.905
RAC1	RHOF	0.905
EPHA5	EPHA1	0.905
RHOBTB1	RAC3	0.905
EPHB1	FGR	0.905
RHOQ	RHOV	0.905
RHOBTB2	RHOC	0.905
RHOD	RHOB	0.905
CDC42	RHOF	0.905
CDC42	RHOU	0.905
RHOG	RHOJ	0.905
EPHB4	EPHB3	0.905
RHOD	RAC2	0.905
RAC1	RHOV	0.905
RHOBTB2	RHOA	0.905
RHOG	RHOBTB1	0.905
HCK	EPHB1	0.905
RHOU	RAC1	0.905
EPHB3	EPHA4	0.905
LYN	FYN	0.905
LYN	EPHB1	0.905
EPHA5	EPHA3	0.905
RAC1	RHOG	0.905
EPHB6	EPHA3	0.904
RHOG	RHOQ	0.904
EPHA1	BLK	0.904
RHOA	RHOU	0.904
RHOBTB2	RAC2	0.904
EPHA5	EPHA8	0.904
EPHB1	EPHB3	0.904
LYN	EPHB2	0.904
LCK	EPHA4	0.904
RHOU	RHOG	0.904
EPHB1	EPHA8	0.904
RHOB	RHOQ	0.904
EPHB2	FGR	0.904
EPHA7	LCK	0.904
EPHA3	EPHA4	0.904
RHOU	RAC2	0.904
EPHB6	EPHA8	0.904
EPHB6	EPHB3	0.904
RHOA	RHOQ	0.904
RHOA	RHOF	0.904
RHOJ	RHOQ	0.904
EPHB1	EPHA6	0.904
EPHA6	EPHB4	0.904
LYN	EPHA6	0.904
EPHB4	EPHA8	0.904
RHOD	RHOF	0.904
LCK	NGEF	0.904
HCK	EPHB2	0.904
EPHA6	EPHB3	0.904
RAC1	RHOJ	0.904
RHOU	RHOQ	0.904
EPHB6	EPHA5	0.904
EPHA4	EPHA8	0.904
EPHB6	EPHA7	0.904
RHOC	RHOB	0.904
EPHB2	EPHA8	0.904
RHOU	RHOV	0.904
RHOG	RAC3	0.904
EPHB4	EPHA4	0.904
FYN	BLK	0.904
RHOC	RHOF	0.904
EPHB1	EPHA3	0.904
CDC42	RHOV	0.904
HCK	EPHA4	0.904
FGR	EPHA4	0.904
EPHB2	EPHA7	0.904
NGEF	BLK	0.904
EPHA6	FGR	0.903
EPHB4	EPHA3	0.903
RAC1	RHOT2	0.903
RAC1	RHOQ	0.903
EPHA5	LCK	0.903
HCK	EPHA7	0.903
EPHA6	EPHB2	0.903
EPHA5	FGR	0.903
EPHA2	BLK	0.903
SRC	BLK	0.903
EPHA7	EPHB4	0.903
LYN	EPHA7	0.903
EPHA6	BLK	0.903
EPHA3	BLK	0.903
EPHB6	EPHB2	0.903
EPHB2	EPHB3	0.903
EPHB1	BLK	0.903
EPHA5	LYN	0.903
EPHA2	EPHA8	0.903
RHOU	RHOC	0.903
LYN	BLK	0.903
EPHA6	LCK	0.903
FGR	EPHA7	0.903
EPHB1	EPHB2	0.903
EPHA5	HCK	0.903
EPHB2	BLK	0.903
RAC2	RHOV	0.903
RHOU	RAC3	0.903
EPHA6	EPHA2	0.903
EPHA5	EPHB4	0.903
RHOJ	RAC2	0.903
EPHB1	EPHB4	0.903
EPHA3	EPHA8	0.903
RAC2	RHOQ	0.902
HCK	EPHA6	0.902
EPHA5	BLK	0.902
RAC3	RHOQ	0.902
RHOJ	RAC3	0.902
RHOA	RHOB	0.902
EPHA7	BLK	0.902
YES1	HCK	0.902
YES1	LYN	0.902
RHOBTB2	RHOBTB1	0.902
EPHA5	EPHB2	0.902
RAC3	RHOF	0.902
YES1	LCK	0.902
EPHA5	EPHB3	0.902
CDC42	RHOQ	0.902
EPHA4	BLK	0.902
EPHB2	EPHB4	0.902
EPHA7	EPHB3	0.902
RHOT1	RAC3	0.902
EPHA3	EPHB3	0.902
EPHB2	EPHA3	0.902
EPHA6	NGEF	0.901
EPHB4	NGEF	0.901
YES1	BLK	0.901
EPHB6	NGEF	0.901
FYN	RAC2	0.9

Gene Ontology Semantic Similarity

Download Tab separated file

#	1942 (EFNA1)	7525 (YES1)	6714 (SRC)	285220 (EPHA6)	2047 (EPHB1)	2045 (EPHA7)	2044 (EPHA5)	2048 (EPHB2)	2051 (EPHB6)	2043 (EPHA4)	998 (CDC42)	1969 (EPHA2)	2268 (FGR)	387 (RHOA)	5881 (RAC3)	5879 (RAC1)	388 (RHOB)	3055 (HCK)	2041 (EPHA1)	2042 (EPHA3)	391 (RHOG)	2534 (FYN)	29984 (RHOD)	23221 (RHOBTB2)	55288 (RHOT1)	4067 (LYN)	9886 (RHOBTB1)	25791 (NGEF)	58480 (RHOU)	54509 (RHOF)	57381 (RHOJ)	399 (RHOH)	389 (RHOC)	2050 (EPHB4)	89941 (RHOT2)	3932 (LCK)	2049 (EPHB3)	23433 (RHOQ)	5880 (RAC2)	2046 (EPHA8)	171177 (RHOV)
1942 (EFNA1)	1.00	0.73	0.66	0.29	0.50	0.41	0.11	0.50	0.14	0.47	0.58	0.57	0.70	0.63	0.65	0.61	0.63	0.71	0.32	0.49	0.63	0.64	0.39	0.63	0.61	0.66	0.39	0.22	0.63	0.39	0.63	0.52	0.63	0.45	0.63	0.64	0.12	0.55	0.63	0.12	0.63
7525 (YES1)	0.73	1.00	0.84	0.46	0.78	0.69	0.37	0.74	0.46	0.71	0.69	0.70	0.92	0.58	0.59	0.74	0.57	0.97	0.61	0.69	0.57	0.79	0.39	0.57	0.57	0.86	0.39	0.20	0.57	0.39	0.57	0.51	0.57	0.77	0.56	0.83	0.46	0.51	0.56	0.35	0.57
6714 (SRC)	0.66	0.84	1.00	0.40	0.73	0.69	0.28	0.71	0.37	0.73	0.71	0.68	0.82	0.58	0.59	0.73	0.58	0.81	0.58	0.66	0.58	0.81	0.39	0.58	0.58	0.83	0.39	0.18	0.58	0.39	0.58	0.55	0.58	0.72	0.56	0.85	0.35	0.51	0.56	0.27	0.58
285220 (EPHA6)	0.29	0.46	0.40	1.00	0.84	0.85	0.90	0.76	0.87	0.67	0.34	0.81	0.42	0.25	0.25	0.35	0.24	0.47	0.79	0.87	0.24	0.39	0.17	0.24	0.42	0.43	0.17	0.27	0.24	0.17	0.24	0.24	0.24	0.85	0.23	0.39	0.87	0.22	0.23	0.89	0.24
2047 (EPHB1)	0.50	0.78	0.73	0.84	1.00	0.93	0.86	0.92	0.90	0.86	0.58	0.93	0.73	0.40	0.42	0.60	0.37	0.77	0.90	0.95	0.37	0.67	0.23	0.37	0.39	0.72	0.23	0.17	0.37	0.23	0.37	0.35	0.37	0.99	0.34	0.70	0.91	0.36	0.34	0.85	0.37
2045 (EPHA7)	0.41	0.69	0.69	0.85	0.93	1.00	0.83	0.88	0.86	0.84	0.53	0.88	0.66	0.36	0.37	0.55	0.33	0.68	0.84	0.91	0.33	0.63	0.21	0.33	0.40	0.65	0.21	0.19	0.33	0.21	0.33	0.32	0.33	0.94	0.31	0.66	0.86	0.32	0.31	0.83	0.33
2044 (EPHA5)	0.11	0.37	0.28	0.90	0.86	0.83	1.00	0.74	0.94	0.66	0.24	0.81	0.35	0.10	0.10	0.26	0.10	0.42	0.85	0.91	0.10	0.28	0.08	0.10	0.15	0.37	0.08	0.11	0.10	0.08	0.10	0.10	0.10	0.89	0.10	0.27	0.96	0.09	0.10	0.99	0.10
2048 (EPHB2)	0.50	0.74	0.71	0.76	0.92	0.88	0.74	1.00	0.79	0.88	0.57	0.86	0.70	0.42	0.43	0.58	0.39	0.73	0.80	0.88	0.39	0.65	0.25	0.39	0.41	0.69	0.25	0.18	0.39	0.25	0.39	0.37	0.39	0.92	0.37	0.68	0.78	0.37	0.37	0.72	0.39
2051 (EPHB6)	0.14	0.46	0.37	0.87	0.90	0.86	0.94	0.79	1.00	0.70	0.30	0.79	0.43	0.13	0.13	0.31	0.13	0.51	0.88	0.87	0.13	0.36	0.10	0.13	0.20	0.46	0.10	0.14	0.13	0.10	0.13	0.13	0.13	0.92	0.13	0.35	0.98	0.12	0.13	0.93	0.13
2043 (EPHA4)	0.47	0.71	0.73	0.67	0.86	0.84	0.66	0.88	0.70	1.00	0.63	0.81	0.71	0.46	0.46	0.64	0.44	0.69	0.81	0.83	0.44	0.65	0.31	0.44	0.43	0.70	0.31	0.16	0.44	0.31	0.44	0.41	0.44	0.86	0.39	0.72	0.68	0.43	0.39	0.64	0.44
998 (CDC42)	0.58	0.69	0.71	0.34	0.58	0.53	0.24	0.57	0.30	0.63	1.00	0.55	0.69	0.78	0.79	0.88	0.79	0.65	0.52	0.53	0.79	0.64	0.67	0.79	0.74	0.64	0.67	0.17	0.79	0.67	0.79	0.70	0.79	0.57	0.74	0.70	0.29	0.78	0.74	0.22	0.79
1969 (EPHA2)	0.57	0.70	0.68	0.81	0.93	0.88	0.81	0.86	0.79	0.81	0.55	1.00	0.66	0.46	0.47	0.57	0.43	0.67	0.82	0.96	0.43	0.61	0.27	0.43	0.44	0.62	0.27	0.17	0.43	0.27	0.43	0.39	0.43	0.93	0.41	0.64	0.79	0.41	0.41	0.80	0.43
2268 (FGR)	0.70	0.92	0.82	0.42	0.73	0.66	0.35	0.70	0.43	0.71	0.69	0.66	1.00	0.60	0.61	0.71	0.60	0.93	0.62	0.65	0.60	0.76	0.42	0.60	0.53	0.81	0.42	0.18	0.60	0.42	0.60	0.53	0.60	0.72	0.52	0.84	0.43	0.53	0.52	0.32	0.60
387 (RHOA)	0.63	0.58	0.58	0.25	0.40	0.36	0.10	0.42	0.13	0.46	0.78	0.46	0.60	1.00	0.95	0.85	0.97	0.52	0.37	0.40	0.97	0.52	0.88	0.97	0.86	0.49	0.88	0.18	0.97	0.88	0.97	0.79	0.97	0.38	0.91	0.59	0.11	0.89	0.91	0.10	0.97
5881 (RAC3)	0.65	0.59	0.59	0.25	0.42	0.37	0.10	0.43	0.13	0.46	0.79	0.47	0.61	0.95	1.00	0.86	0.98	0.54	0.38	0.41	0.98	0.53	0.89	0.98	0.88	0.50	0.89	0.18	0.98	0.89	0.98	0.80	0.98	0.39	0.93	0.59	0.11	0.90	0.93	0.11	0.98
5879 (RAC1)	0.61	0.74	0.73	0.35	0.60	0.55	0.26	0.58	0.31	0.64	0.88	0.57	0.71	0.85	0.86	1.00	0.86	0.67	0.58	0.55	0.86	0.65	0.77	0.86	0.79	0.65	0.77	0.18	0.86	0.77	0.86	0.75	0.86	0.59	0.81	0.71	0.31	0.80	0.81	0.24	0.86
388 (RHOB)	0.63	0.57	0.58	0.24	0.37	0.33	0.10	0.39	0.13	0.44	0.79	0.43	0.60	0.97	0.98	0.86	1.00	0.51	0.37	0.37	1.00	0.51	0.94	1.00	0.89	0.47	0.94	0.18	1.00	0.94	1.00	0.80	1.00	0.34	0.94	0.58	0.11	0.92	0.94	0.10	1.00
3055 (HCK)	0.71	0.97	0.81	0.47	0.77	0.68	0.42	0.73	0.51	0.69	0.65	0.67	0.93	0.52	0.54	0.67	0.51	1.00	0.60	0.66	0.51	0.77	0.32	0.51	0.51	0.84	0.32	0.19	0.51	0.32	0.51	0.45	0.51	0.76	0.49	0.82	0.53	0.46	0.49	0.40	0.51
2041 (EPHA1)	0.32	0.61	0.58	0.79	0.90	0.84	0.85	0.80	0.88	0.81	0.52	0.82	0.62	0.37	0.38	0.58	0.37	0.60	1.00	0.87	0.37	0.50	0.33	0.37	0.28	0.56	0.33	0.13	0.37	0.33	0.37	0.33	0.37	0.90	0.24	0.57	0.88	0.35	0.24	0.84	0.37
2042 (EPHA3)	0.49	0.69	0.66	0.87	0.95	0.91	0.91	0.88	0.87	0.83	0.53	0.96	0.65	0.40	0.41	0.55	0.37	0.66	0.87	1.00	0.37	0.60	0.23	0.37	0.38	0.61	0.23	0.16	0.37	0.23	0.37	0.34	0.37	0.96	0.34	0.63	0.87	0.36	0.34	0.91	0.37
391 (RHOG)	0.63	0.57	0.58	0.24	0.37	0.33	0.10	0.39	0.13	0.44	0.79	0.43	0.60	0.97	0.98	0.86	1.00	0.51	0.37	0.37	1.00	0.51	0.94	1.00	0.89	0.47	0.94	0.18	1.00	0.94	1.00	0.80	1.00	0.34	0.94	0.58	0.11	0.92	0.94	0.10	1.00
2534 (FYN)	0.64	0.79	0.81	0.39	0.67	0.63	0.28	0.65	0.36	0.65	0.64	0.61	0.76	0.52	0.53	0.65	0.51	0.77	0.50	0.60	0.51	1.00	0.33	0.51	0.52	0.76	0.33	0.29	0.51	0.33	0.51	0.50	0.51	0.66	0.50	0.78	0.35	0.44	0.50	0.27	0.51
29984 (RHOD)	0.39	0.39	0.39	0.17	0.23	0.21	0.08	0.25	0.10	0.31	0.67	0.27	0.42	0.88	0.89	0.77	0.94	0.32	0.33	0.23	0.94	0.33	1.00	0.94	0.78	0.30	1.00	0.12	0.94	1.00	0.94	0.72	0.94	0.22	0.87	0.41	0.09	0.86	0.87	0.08	0.94
23221 (RHOBTB2)	0.63	0.57	0.58	0.24	0.37	0.33	0.10	0.39	0.13	0.44	0.79	0.43	0.60	0.97	0.98	0.86	1.00	0.51	0.37	0.37	1.00	0.51	0.94	1.00	0.89	0.47	0.94	0.18	1.00	0.94	1.00	0.80	1.00	0.34	0.94	0.58	0.11	0.92	0.94	0.10	1.00
55288 (RHOT1)	0.61	0.57	0.58	0.42	0.39	0.40	0.15	0.41	0.20	0.43	0.74	0.44	0.53	0.86	0.88	0.79	0.89	0.51	0.28	0.38	0.89	0.52	0.78	0.89	1.00	0.49	0.78	0.29	0.89	0.78	0.89	0.74	0.89	0.37	0.93	0.56	0.17	0.81	0.93	0.16	0.89
4067 (LYN)	0.66	0.86	0.83	0.43	0.72	0.65	0.37	0.69	0.46	0.70	0.64	0.62	0.81	0.49	0.50	0.65	0.47	0.84	0.56	0.61	0.47	0.76	0.30	0.47	0.49	1.00	0.30	0.17	0.47	0.30	0.47	0.43	0.47	0.71	0.46	0.79	0.47	0.43	0.46	0.35	0.47
9886 (RHOBTB1)	0.39	0.39	0.39	0.17	0.23	0.21	0.08	0.25	0.10	0.31	0.67	0.27	0.42	0.88	0.89	0.77	0.94	0.32	0.33	0.23	0.94	0.33	1.00	0.94	0.78	0.30	1.00	0.12	0.94	1.00	0.94	0.72	0.94	0.22	0.87	0.41	0.09	0.86	0.87	0.08	0.94
25791 (NGEF)	0.22	0.20	0.18	0.27	0.17	0.19	0.11	0.18	0.14	0.16	0.17	0.17	0.18	0.18	0.18	0.18	0.18	0.19	0.13	0.16	0.18	0.29	0.12	0.18	0.29	0.17	0.12	1.00	0.18	0.12	0.18	0.23	0.18	0.16	0.18	0.18	0.12	0.16	0.18	0.12	0.18
58480 (RHOU)	0.63	0.57	0.58	0.24	0.37	0.33	0.10	0.39	0.13	0.44	0.79	0.43	0.60	0.97	0.98	0.86	1.00	0.51	0.37	0.37	1.00	0.51	0.94	1.00	0.89	0.47	0.94	0.18	1.00	0.94	1.00	0.80	1.00	0.34	0.94	0.58	0.11	0.92	0.94	0.10	1.00
54509 (RHOF)	0.39	0.39	0.39	0.17	0.23	0.21	0.08	0.25	0.10	0.31	0.67	0.27	0.42	0.88	0.89	0.77	0.94	0.32	0.33	0.23	0.94	0.33	1.00	0.94	0.78	0.30	1.00	0.12	0.94	1.00	0.94	0.72	0.94	0.22	0.87	0.41	0.09	0.86	0.87	0.08	0.94
57381 (RHOJ)	0.63	0.57	0.58	0.24	0.37	0.33	0.10	0.39	0.13	0.44	0.79	0.43	0.60	0.97	0.98	0.86	1.00	0.51	0.37	0.37	1.00	0.51	0.94	1.00	0.89	0.47	0.94	0.18	1.00	0.94	1.00	0.80	1.00	0.34	0.94	0.58	0.11	0.92	0.94	0.10	1.00
399 (RHOH)	0.52	0.51	0.55	0.24	0.35	0.32	0.10	0.37	0.13	0.41	0.70	0.39	0.53	0.79	0.80	0.75	0.80	0.45	0.33	0.34	0.80	0.50	0.72	0.80	0.74	0.43	0.72	0.23	0.80	0.72	0.80	1.00	0.80	0.33	0.74	0.55	0.10	0.75	0.74	0.10	0.80
389 (RHOC)	0.63	0.57	0.58	0.24	0.37	0.33	0.10	0.39	0.13	0.44	0.79	0.43	0.60	0.97	0.98	0.86	1.00	0.51	0.37	0.37	1.00	0.51	0.94	1.00	0.89	0.47	0.94	0.18	1.00	0.94	1.00	0.80	1.00	0.34	0.94	0.58	0.11	0.92	0.94	0.10	1.00
2050 (EPHB4)	0.45	0.77	0.72	0.85	0.99	0.94	0.89	0.92	0.92	0.86	0.57	0.93	0.72	0.38	0.39	0.59	0.34	0.76	0.90	0.96	0.34	0.66	0.22	0.34	0.37	0.71	0.22	0.16	0.34	0.22	0.34	0.33	0.34	1.00	0.31	0.70	0.92	0.34	0.31	0.87	0.34
89941 (RHOT2)	0.63	0.56	0.56	0.23	0.34	0.31	0.10	0.37	0.13	0.39	0.74	0.41	0.52	0.91	0.93	0.81	0.94	0.49	0.24	0.34	0.94	0.50	0.87	0.94	0.93	0.46	0.87	0.18	0.94	0.87	0.94	0.74	0.94	0.31	1.00	0.55	0.11	0.87	1.00	0.10	0.94
3932 (LCK)	0.64	0.83	0.85	0.39	0.70	0.66	0.27	0.68	0.35	0.72	0.70	0.64	0.84	0.59	0.59	0.71	0.58	0.82	0.57	0.63	0.58	0.78	0.41	0.58	0.56	0.79	0.41	0.18	0.58	0.41	0.58	0.55	0.58	0.70	0.55	1.00	0.34	0.52	0.55	0.26	0.58
2049 (EPHB3)	0.12	0.46	0.35	0.87	0.91	0.86	0.96	0.78	0.98	0.68	0.29	0.79	0.43	0.11	0.11	0.31	0.11	0.53	0.88	0.87	0.11	0.35	0.09	0.11	0.17	0.47	0.09	0.12	0.11	0.09	0.11	0.10	0.11	0.92	0.11	0.34	1.00	0.10	0.11	0.95	0.11
23433 (RHOQ)	0.55	0.51	0.51	0.22	0.36	0.32	0.09	0.37	0.12	0.43	0.78	0.41	0.53	0.89	0.90	0.80	0.92	0.46	0.35	0.36	0.92	0.44	0.86	0.92	0.81	0.43	0.86	0.16	0.92	0.86	0.92	0.75	0.92	0.34	0.87	0.52	0.10	1.00	0.87	0.09	0.92
5880 (RAC2)	0.63	0.56	0.56	0.23	0.34	0.31	0.10	0.37	0.13	0.39	0.74	0.41	0.52	0.91	0.93	0.81	0.94	0.49	0.24	0.34	0.94	0.50	0.87	0.94	0.93	0.46	0.87	0.18	0.94	0.87	0.94	0.74	0.94	0.31	1.00	0.55	0.11	0.87	1.00	0.10	0.94
2046 (EPHA8)	0.12	0.35	0.27	0.89	0.85	0.83	0.99	0.72	0.93	0.64	0.22	0.80	0.32	0.10	0.11	0.24	0.10	0.40	0.84	0.91	0.10	0.27	0.08	0.10	0.16	0.35	0.08	0.12	0.10	0.08	0.10	0.10	0.10	0.87	0.10	0.26	0.95	0.09	0.10	1.00	0.10
171177 (RHOV)	0.63	0.57	0.58	0.24	0.37	0.33	0.10	0.39	0.13	0.44	0.79	0.43	0.60	0.97	0.98	0.86	1.00	0.51	0.37	0.37	1.00	0.51	0.94	1.00	0.89	0.47	0.94	0.18	1.00	0.94	1.00	0.80	1.00	0.34	0.94	0.58	0.11	0.92	0.94	0.10	1.00

Association with High Altitude

Protein Official symbol	Source Organism	Tissue of Expression	Level of hypoxia	Altitude	Duration of experiment	Level of expression	Fold change	Experiment details	geographical location	ethnicity of the patients	Control group	Control (Fold change)	Reference (PMID)
NGEF	Toad	Heart	-	3464 m	33 day	upregulated	2.3940664	RNA-seq	Tibetan Plateau	Asiatic toad	1	Zoige (High altitute Toad) Vs Chengdu (Low altitude toad) -	28673260

Association with TF

TF	TF Entrez	Gene	Gene Entrez	Type	PMID	Database
FOXA1	3169	NGEF	25791	proximal_filtered	22955619	TRANSFAC
FOXA2	3170	NGEF	25791	proximal_filtered	22955619	TRANSFAC

Association with miRNA

miRTarBase ID	miRNA	Species (miRNA)	Protein Official Symbol	Human Entrez ID	Species (Target Gene)	Experiments	Support Type	References (PMID)

Gene Ontology

ID	GO ID	GO Term	GO Type
25791	GO:0043087	regulation of GTPase activity	GOTERM_BP_DIRECT
25791	GO:0043547	positive regulation of GTPase activity	GOTERM_BP_DIRECT
25791	GO:0035023	regulation of Rho protein signal transduction	GOTERM_BP_DIRECT
25791	GO:0043065	positive regulation of apoptotic process	GOTERM_BP_DIRECT
25791	GO:0005089	Rho guanyl-nucleotide exchange factor activity	GOTERM_MF_DIRECT
25791	GO:0051056	regulation of small GTPase mediated signal transduction	GOTERM_BP_DIRECT
25791	GO:0016020	membrane	GOTERM_CC_DIRECT
25791	GO:0030426	growth cone	GOTERM_CC_DIRECT
25791	GO:0005085	guanyl-nucleotide exchange factor activity	GOTERM_MF_DIRECT
25791	GO:0048013	ephrin receptor signaling pathway	GOTERM_BP_DIRECT
25791	GO:0061002	negative regulation of dendritic spine morphogenesis	GOTERM_BP_DIRECT
25791	GO:0005829	cytosol	GOTERM_CC_DIRECT

Pathways

Human Entrez ID	KEGG ID	KEGG Term
25791	hsa04360	Axon guidance

Association with Disease

Protein Official Symbol	Human Entrez ID	Disease Name	Disease Id	Disease Semantic Type	Semantic score	DSI	DPI	Disease Type

Association with Drug

Protein Official Symbol	Human Entrez ID	drug_claim_primary_name	drug_name	drug_chembl_id	interaction_types