ALTITUDEOMICSDB

Chloride intracellular channel protein 4

AltitudeomicsDB

Protein Official symbol	CLIC4
Aliases	CLIC4
Chromosomal Location	1
Length	253
Uniprot ID	Q9Y696
EC number	None
Protein family Information(Pfam)	None
PDB id	2AHE;2D2Z;3OQS;
InterPro ID	IPR002946;IPR010987;IPR036282;IPR040079;IPR036249;
dbSNP	None

Protein Protein Interaction

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AltitudeomicsDB

Protein 1	Protein 2	Combine Score
CLIC2	CLIC5	0.973
TPRN	CLIC5	0.961
CLIC4	CLIC2	0.959
CLIC4	CLIC5	0.943
CLIC4	CRKL	0.873
TPRN	CLIC4	0.869
CLIC4	CLIC6	0.853
CLIC4	PPM1A	0.781
CLIC4	UBA2	0.725
CLIC4	ACADS	0.725
CLIC4	HIVEP2	0.715

Gene Ontology Semantic Similarity

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#	1193 (CLIC2)	286262 (TPRN)	25932 (CLIC4)	53405 (CLIC5)	1399 (CRKL)	54102 (CLIC6)	5494 (PPM1A)	10054 (UBA2)	35 (ACADS)
1193 (CLIC2)	1.00	0.58	0.83	1.00	0.59	0.38	0.46	0.50	0.27
286262 (TPRN)	0.58	1.00	0.65	1.00	0.69	0.48	0.60	0.58	0.28
25932 (CLIC4)	0.83	0.65	1.00	1.00	0.64	0.44	0.50	0.52	0.14
53405 (CLIC5)	1.00	1.00	1.00	1.00	1.00	0.54	1.00	1.00	0.18
1399 (CRKL)	0.59	0.69	0.64	1.00	1.00	0.41	0.60	0.58	0.14
54102 (CLIC6)	0.38	0.48	0.44	0.54	0.41	1.00	0.37	0.33	0.09
5494 (PPM1A)	0.46	0.60	0.50	1.00	0.60	0.37	1.00	0.51	0.16
10054 (UBA2)	0.50	0.58	0.52	1.00	0.58	0.33	0.51	1.00	0.15
35 (ACADS)	0.27	0.28	0.14	0.18	0.14	0.09	0.16	0.15	1.00

Association with High Altitude

Protein Official symbol	Source Organism	Tissue of Expression	Level of hypoxia	Altitude	Duration of experiment	Level of expression	Fold change	Experiment details	geographical location	ethnicity of the patients	Control group	Control (Fold change)	Reference (PMID)
CLIC4	Human	Pulmonary Artery	3-10% Oxygen	5800 m	2 hours	downregulated	-	-	-	-	-	Soldier exposed to high altitude compared to their low altitude profile	http://dx.doi.org/10.4172/jpb.S3-004

Association with TF

TF	TF Entrez	Gene	Gene Entrez	Type	PMID	Database
EP300	2033	CLIC4	25932	distal	22955619	TRANSFAC
EBF1	1879	CLIC4	25932	proximal_filtered	22955619	TRANSFAC

Association with miRNA

miRTarBase ID	miRNA	Species (miRNA)	Protein Official Symbol	Human Entrez ID	Species (Target Gene)	Experiments	Support Type	References (PMID)
MIRT016555	hsa-miR-193b-3p	Homo sapiens	CLIC4	25932	Homo sapiens	Proteomics	Functional MTI (Weak)	21512034
MIRT018964	hsa-miR-335-5p	Homo sapiens	CLIC4	25932	Homo sapiens	Microarray	Functional MTI (Weak)	18185580
MIRT020967	hsa-miR-155-5p	Homo sapiens	CLIC4	25932	Homo sapiens	Proteomics	Functional MTI (Weak)	20584899
MIRT021633	hsa-miR-142-3p	Homo sapiens	CLIC4	25932	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	22473208
MIRT021633	hsa-miR-142-3p	Homo sapiens	CLIC4	25932	Homo sapiens	Microarray	Functional MTI (Weak)	17612493
MIRT023398	hsa-miR-122-5p	Homo sapiens	CLIC4	25932	Homo sapiens	Microarray	Functional MTI (Weak)	17612493
MIRT023398	hsa-miR-122-5p	Homo sapiens	CLIC4	25932	Homo sapiens	Luciferase reporter assay//qRT-PCR	Functional MTI	23793894
MIRT023398	hsa-miR-122-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT023398	hsa-miR-122-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT038674	hsa-miR-10a-3p	Homo sapiens	CLIC4	25932	Homo sapiens	CLASH	Functional MTI (Weak)	23622248
MIRT044169	hsa-miR-130b-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT044169	hsa-miR-130b-3p	Homo sapiens	CLIC4	25932	Homo sapiens	CLASH	Functional MTI (Weak)	23622248
MIRT044169	hsa-miR-130b-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT050194	hsa-miR-26a-5p	Homo sapiens	CLIC4	25932	Homo sapiens	CLASH	Functional MTI (Weak)	23622248
MIRT065619	hsa-miR-139-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT065616	hsa-miR-19a-3p	Homo sapiens	CLIC4	25932	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	22473208
MIRT065632	hsa-miR-4742-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT065621	hsa-miR-301a-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT065621	hsa-miR-301a-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT065623	hsa-miR-519b-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT065624	hsa-miR-519a-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT065627	hsa-miR-301b-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT065617	hsa-miR-19b-3p	Homo sapiens	CLIC4	25932	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	22473208
MIRT065618	hsa-miR-106a-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT065620	hsa-miR-130a-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT065622	hsa-miR-519c-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT065625	hsa-miR-1323	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT065627	hsa-miR-301b-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT065624	hsa-miR-519a-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT065628	hsa-miR-548o-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT065630	hsa-miR-3666	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT065633	hsa-miR-4772-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT065629	hsa-miR-4295	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT065629	hsa-miR-4295	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT065632	hsa-miR-4742-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT065619	hsa-miR-139-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT065630	hsa-miR-3666	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT065622	hsa-miR-519c-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT065626	hsa-miR-454-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT065628	hsa-miR-548o-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT065633	hsa-miR-4772-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT065625	hsa-miR-1323	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT065618	hsa-miR-106a-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT065620	hsa-miR-130a-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT065626	hsa-miR-454-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT065623	hsa-miR-519b-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT065631	hsa-miR-4476	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22100165
MIRT065634	hsa-miR-6876-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22100165
MIRT113353	hsa-miR-665	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT113353	hsa-miR-665	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT135347	hsa-miR-577	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22100165
MIRT135345	hsa-miR-374a-5p	Homo sapiens	CLIC4	25932	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	22473208
MIRT187297	hsa-miR-4744	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT187300	hsa-miR-6880-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT187295	hsa-miR-548ah-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT187290	hsa-miR-504-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT187353	hsa-miR-4799-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22100165
MIRT187296	hsa-miR-4509	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT187296	hsa-miR-4509	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT187295	hsa-miR-548ah-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT187290	hsa-miR-504-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT187294	hsa-miR-3609	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT187297	hsa-miR-4744	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22100165
MIRT187294	hsa-miR-3609	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT187296	hsa-miR-4509	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22100165
MIRT187291	hsa-miR-561-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT187291	hsa-miR-561-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT187297	hsa-miR-4744	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT187300	hsa-miR-6880-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT338103	hsa-miR-4796-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT338103	hsa-miR-4796-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT384602	hsa-miR-3163	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22100165
MIRT384604	hsa-miR-1273e	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22100165
MIRT384605	hsa-miR-3915	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22100165
MIRT445623	hsa-miR-1236-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22100165
MIRT445618	hsa-miR-526b-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22100165
MIRT445621	hsa-miR-493-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22100165
MIRT445624	hsa-miR-3662	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22100165
MIRT445615	hsa-miR-4689	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22100165
MIRT445614	hsa-miR-6858-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22100165
MIRT445619	hsa-miR-3928-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22100165
MIRT445622	hsa-miR-6515-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22100165
MIRT445617	hsa-miR-580-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22100165
MIRT445616	hsa-miR-1224-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22100165
MIRT445620	hsa-miR-539-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22100165
MIRT507728	hsa-miR-144-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT507722	hsa-miR-545-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT507730	hsa-miR-362-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT507731	hsa-miR-329-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT507724	hsa-miR-4514	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT507728	hsa-miR-144-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT507726	hsa-miR-4269	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT507721	hsa-miR-3941	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT507729	hsa-miR-603	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT507729	hsa-miR-603	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT507730	hsa-miR-362-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT507723	hsa-miR-4692	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT507723	hsa-miR-4692	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT507726	hsa-miR-4269	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT507720	hsa-miR-101-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT507732	hsa-miR-8485	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT507721	hsa-miR-3941	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT507724	hsa-miR-4514	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT507725	hsa-miR-6715b-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT507731	hsa-miR-329-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT507722	hsa-miR-545-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT507720	hsa-miR-101-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT507727	hsa-miR-383-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT507732	hsa-miR-8485	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT507725	hsa-miR-6715b-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT507727	hsa-miR-383-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT524463	hsa-miR-4764-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT524465	hsa-miR-1236-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT524466	hsa-miR-508-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT524466	hsa-miR-508-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT524464	hsa-miR-4765	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT524465	hsa-miR-1236-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT524463	hsa-miR-4764-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT524464	hsa-miR-4765	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT548815	hsa-miR-5695	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT548816	hsa-miR-519d-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT548817	hsa-miR-6800-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT548819	hsa-miR-526b-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT548813	hsa-miR-8071	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT548822	hsa-miR-20a-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT548814	hsa-miR-520f-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT548815	hsa-miR-5695	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT548823	hsa-miR-17-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT548817	hsa-miR-6800-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT548810	hsa-miR-519e-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT548812	hsa-miR-3165	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT548824	hsa-miR-106b-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT548812	hsa-miR-3165	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT548816	hsa-miR-519d-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT548821	hsa-miR-20b-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT548822	hsa-miR-20a-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT548823	hsa-miR-17-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT548825	hsa-miR-106a-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT548814	hsa-miR-520f-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT548818	hsa-miR-93-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT548820	hsa-miR-519d-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT548821	hsa-miR-20b-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT548810	hsa-miR-519e-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT548820	hsa-miR-519d-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT548811	hsa-miR-515-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT548819	hsa-miR-526b-3p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT548813	hsa-miR-8071	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT548811	hsa-miR-515-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT548818	hsa-miR-93-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT548825	hsa-miR-106a-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT548824	hsa-miR-106b-5p	Homo sapiens	CLIC4	25932	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT704621	hsa-miR-4420	Homo sapiens	CLIC4	25932	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT704626	hsa-miR-1910-5p	Homo sapiens	CLIC4	25932	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT704623	hsa-miR-181b-2-3p	Homo sapiens	CLIC4	25932	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT704629	hsa-miR-129-1-3p	Homo sapiens	CLIC4	25932	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT704622	hsa-miR-181b-3p	Homo sapiens	CLIC4	25932	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT704625	hsa-miR-4264	Homo sapiens	CLIC4	25932	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT704628	hsa-miR-129-2-3p	Homo sapiens	CLIC4	25932	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT704630	hsa-miR-6779-3p	Homo sapiens	CLIC4	25932	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT704627	hsa-miR-455-3p	Homo sapiens	CLIC4	25932	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT704631	hsa-miR-4687-5p	Homo sapiens	CLIC4	25932	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT704624	hsa-miR-4290	Homo sapiens	CLIC4	25932	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552

Gene Ontology

ID	GO ID	GO Term	GO Type
25932	GO:0005829	cytosol	GOTERM_CC_DIRECT
25932	GO:0030496	midbody	GOTERM_CC_DIRECT
25932	GO:0005622	intracellular	GOTERM_CC_DIRECT
25932	GO:0009986	cell surface	GOTERM_CC_DIRECT
25932	GO:0015630	microtubule cytoskeleton	GOTERM_CC_DIRECT
25932	GO:0016363	nuclear matrix	GOTERM_CC_DIRECT
25932	GO:0034707	chloride channel complex	GOTERM_CC_DIRECT
25932	GO:0006821	chloride transport	GOTERM_BP_DIRECT
25932	GO:0006915	apoptotic process	GOTERM_BP_DIRECT
25932	GO:0005244	intracellular calcium activated chloride channel activity	GOTERM_MF_DIRECT
25932	GO:0045177	apical part of cell	GOTERM_CC_DIRECT
25932	GO:0005254	voltage-gated potassium channel activity	GOTERM_MF_DIRECT
25932	GO:0015629	actin cytoskeleton	GOTERM_CC_DIRECT
25932	GO:0071277	cellular response to calcium ion	GOTERM_BP_DIRECT
25932	GO:0001525	angiogenesis	GOTERM_BP_DIRECT
25932	GO:0001886	endothelial cell morphogenesis	GOTERM_BP_DIRECT
25932	GO:0048754	branching morphogenesis of an epithelial tube	GOTERM_BP_DIRECT
25932	GO:0004364	glutamate dehydrogenase [NAD	GOTERM_MF_DIRECT
25932	GO:0005902	microvillus	GOTERM_CC_DIRECT
25932	GO:0061299	retina vasculature morphogenesis in camera-type eye	GOTERM_BP_DIRECT
25932	GO:0005737	cytoplasm	GOTERM_CC_DIRECT
25932	GO:0048471	perinuclear region of cytoplasm	GOTERM_CC_DIRECT
25932	GO:0030216	keratinocyte differentiation	GOTERM_BP_DIRECT
25932	GO:0034765	regulation of ion transmembrane transport	GOTERM_BP_DIRECT
25932	GO:0005739	mitochondrion	GOTERM_CC_DIRECT
25932	GO:0030154	cell differentiation	GOTERM_BP_DIRECT
25932	GO:0030336	negative regulation of cell migration	GOTERM_BP_DIRECT
25932	GO:0009566	fertilization	GOTERM_BP_DIRECT
25932	GO:0035264	multicellular organism growth	GOTERM_BP_DIRECT
25932	GO:0005886	plasma membrane	GOTERM_CC_DIRECT
25932	GO:0005911	cell-cell junction	GOTERM_CC_DIRECT
25932	GO:0007035	vacuolar acidification	GOTERM_BP_DIRECT
25932	GO:0035088	establishment or maintenance of apical/basal cell polarity	GOTERM_BP_DIRECT
25932	GO:0030659	cytoplasmic vesicle membrane	GOTERM_CC_DIRECT
25932	GO:0006749	glutathione metabolic process	GOTERM_BP_DIRECT
25932	GO:0051493	regulation of cytoskeleton organization	GOTERM_BP_DIRECT
25932	GO:0005515	protein binding	GOTERM_MF_DIRECT
25932	GO:0070062	extracellular exosome	GOTERM_CC_DIRECT
25932	GO:1902476	chloride transmembrane transport	GOTERM_BP_DIRECT
25932	GO:0005813	centrosome	GOTERM_CC_DIRECT

Pathways

Human Entrez ID	KEGG ID	KEGG Term

Association with Disease

Protein Official Symbol	Human Entrez ID	Disease Name	Disease Id	Disease Semantic Type	Semantic score	DSI	DPI	Disease Type
CLIC4	25932	Degenerative polyarthritis	C0029408	Disease or Syndrome	0.3	0.696	0.241	disease
CLIC4	25932	Weight Gain	C0043094	Finding	0.3	0.696	0.241	phenotype
CLIC4	25932	Osteoarthrosis Deformans	C0086743	Disease or Syndrome	0.3	0.696	0.241	disease
CLIC4	25932	Prostatic Neoplasms	C0033578	Neoplastic Process	0.3	0.696	0.241	group
CLIC4	25932	Malignant neoplasm of prostate	C0376358	Neoplastic Process	0.3	0.696	0.241	disease

Association with Drug

Protein Official Symbol	Human Entrez ID	drug_claim_primary_name	drug_name	drug_chembl_id	interaction_types