Taperin

AltitudeomicsDB
Protein Official symbol TPRN
Aliases TPRN C9orf75
Chromosomal Location  9
Length 711
Uniprot ID Q4KMQ1
EC number None
Protein family Information(Pfam) PF13914;PF13916;
PDB id None
InterPro ID IPR025903;IPR025907;IPR026671;IPR033359;
dbSNP None

Protein Protein Interaction

0%
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AltitudeomicsDB
Protein 1 Protein 2 Combine Score
TPRN CLIC5 0.961
CLIC4 CLIC5 0.943
TPRN TSPEAR 0.87
TPRN CLIC4 0.869
TPRN SMPX 0.861
TPRN PPP1CB 0.86
CEACAM16 TSPEAR 0.856
SMPX TSPEAR 0.855
CEACAM16 SMPX 0.834
CEACAM16 TPRN 0.829
GPSM2 TSPEAR 0.803
TPRN GPSM2 0.795
PTPRQ TPRN 0.77
CEACAM16 GPSM2 0.765
GPSM2 SMPX 0.764
TPRN PTPRR 0.713
TPRN TRIOBP 0.704
Gene Ontology Semantic Similarity
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# 286262 (TPRN) 25932 (CLIC4) 388551 (CEACAM16) 29899 (GPSM2) 53405 (CLIC5) 54084 (TSPEAR) 5500 (PPP1CB) 5801 (PTPRR)
286262 (TPRN) 1.00 0.65 0.82 0.74 1.00 1.00 0.55 0.58
25932 (CLIC4) 0.65 1.00 0.82 0.68 1.00 0.48 0.44 0.48
388551 (CEACAM16) 0.82 0.82 1.00 1.00 0.82 0.38 0.82 0.82
29899 (GPSM2) 0.74 0.68 1.00 1.00 1.00 0.48 0.59 0.62
53405 (CLIC5) 1.00 1.00 0.82 1.00 1.00 0.48 1.00 1.00
54084 (TSPEAR) 1.00 0.48 0.38 0.48 0.48 1.00 0.48 0.48
5500 (PPP1CB) 0.55 0.44 0.82 0.59 1.00 0.48 1.00 0.82
5801 (PTPRR) 0.58 0.48 0.82 0.62 1.00 0.48 0.82 1.00
Association with High Altitude
Protein Official symbol Source Organism Tissue of Expression Level of hypoxia Altitude Duration of experiment Level of expression Fold change Experiment details geographical location ethnicity of the patients Control group Control (Fold change) Reference (PMID)
TPRN Bird Kidney - 4000 m Native upregulated 1.4 Sequencing Central Asia L. dichrous (Bird) 1 L. dichrous vs. Po. Palustris 31127049
Association with TF
TF TF Entrez Gene Gene Entrez Type PMID Database
ESRRA 2101 TPRN 286262 proximal_filtered 22955619 TRANSFAC
TAF1 6872 TPRN 286262 proximal_filtered 22955619 TRANSFAC
Association with miRNA
miRTarBase ID miRNA Species (miRNA) Protein Official Symbol Human Entrez ID Species (Target Gene) Experiments Support Type References (PMID)
MIRT039802 hsa-miR-615-3p Homo sapiens TPRN 286262 Homo sapiens CLASH Functional MTI (Weak) 23622248
MIRT049039 hsa-miR-92a-3p Homo sapiens TPRN 286262 Homo sapiens CLASH Functional MTI (Weak) 23622248
Gene Ontology
ID GO ID GO Term GO Type
286262 GO:0019902 protein kinase binding GOTERM_MF_DIRECT
286262 GO:0007605 sensory perception of sound GOTERM_BP_DIRECT
286262 GO:0032420 stereocilium GOTERM_CC_DIRECT
Pathways
Human Entrez ID KEGG ID KEGG Term
Association with Disease
Protein Official Symbol Human Entrez ID Disease Name Disease Id Disease Semantic Type Semantic score DSI DPI Disease Type
TPRN 286262 Deafness, Autosomal Recessive 79 C2750082 Disease or Syndrome 0.6 0.834 0.103 disease
Association with Drug
Protein Official Symbol Human Entrez ID drug_claim_primary_name drug_name drug_chembl_id interaction_types