ALTITUDEOMICSDB

Bloom syndrome protein

AltitudeomicsDB

Protein Official symbol	BLM
Aliases	BLM RECQ2 RECQL3
Chromosomal Location	15
Length	1417
Uniprot ID	P54132
EC number	3.6.4.12
Protein family Information(Pfam)	PF08072;PF16204;PF16202;PF00270;PF00271;PF00570;PF16124;PF09382;
PDB id	2KV2;2MH9;2RRD;3WE2;3WE3;4CDG;4CGZ;4O3M;5LUP;5MK5;5U6K;
InterPro ID	IPR012532;IPR032439;IPR032437;IPR011545;IPR002464;IPR004589;IPR014001;IPR001650;IPR010997;IPR002121;IPR027417;IPR032284;IPR018982;IPR036388;IPR036390;
dbSNP	rs28384988 rs28384991 rs28385012 rs747281324 rs767086502 rs137853152 rs2227935 rs758311406 rs137853153 rs2229035 rs367543029 rs28385141 rs1801256 rs28385142 rs7167216

Protein Protein Interaction

Download Tab separated file

AltitudeomicsDB

Protein 1	Protein 2	Combine Score
POLD1	POLE	0.999
RFC4	PCNA	0.998
POLE	POLE2	0.998
EME1	MUS81	0.998
RAD51	RAD52	0.998
RAD50	MRE11A	0.998
CHEK1	ATM	0.998
RAD51	BRCA2	0.997
RPA2	RPA1	0.997
CHEK1	RAD51	0.997
EXO1	DNA2	0.997
CHEK1	EXO1	0.997
BRCA1	BRCA2	0.996
PCNA	RPA2	0.996
C19orf40	FANCM	0.996
RAD17	HUS1	0.996
RAD51	EXO1	0.996
FANCA	FANCG	0.996
CHEK1	TOPBP1	0.995
RMI1	RMI2	0.995
CHEK1	ATR	0.995
TOP3A	RMI1	0.995
MSH4	MLH1	0.995
FANCA	FANCC	0.995
FANCA	FANCE	0.994
FANCG	FANCF	0.994
FANCG	FANCC	0.994
EXO1	BLM	0.994
FANCC	FANCE	0.994
ATM	TOPBP1	0.994
MLH3	MSH4	0.994
TIMELESS	TIPIN	0.994
FANCF	FANCE	0.993
EXO1	MLH1	0.993
FANCL	FANCA	0.993
FANCA	FANCF	0.993
ERCC4	ERCC1	0.993
EXO1	ATM	0.993
FANCG	FANCE	0.993
FANCF	FANCC	0.993
FANCL	FANCM	0.993
RAD17	CHEK1	0.993
RAD17	ATM	0.993
RAD51	DNA2	0.992
PCNA	RPA1	0.992
FANCL	FANCF	0.992
CHEK1	TIPIN	0.992
EXO1	WRN	0.992
BRCA2	ATM	0.991
RAD51	BLM	0.991
POLD1	POLE2	0.991
EXO1	ATR	0.991
FANCL	FANCE	0.991
MUS81	ERCC1	0.991
FANCL	FANCG	0.991
EME1	ERCC1	0.991
FANCL	FANCC	0.991
BRCA1	RAD51	0.991
BRCA1	ATM	0.991
TOPBP1	HUS1	0.991
MSH5	MLH1	0.991
PCNA	RFC2	0.991
RAD51	ATM	0.991
C19orf40	FANCA	0.991
TIMELESS	CHEK1	0.99
WRN	ATM	0.99
RFC4	POLE2	0.99
RAD17	TOPBP1	0.99
RFC4	RFC2	0.99
RAD52	ATM	0.99
TOP3A	BLM	0.99
EME1	EXO1	0.99
MSH5	MLH3	0.99
MRE11A	ATM	0.989
TOP3A	MUS81	0.989
CHEK1	HUS1	0.989
ERCC4	MUS81	0.989
DNA2	WRN	0.989
RAD51	MUS81	0.989
RAD17	ATR	0.989
XRCC3	BRCA2	0.988
ATR	TOPBP1	0.988
CHEK1	BLM	0.988
RAD51	MLH1	0.988
MUS81	FANCM	0.988
EXO1	RAD52	0.988
RAD17	RFC2	0.988
RPA2	ATM	0.988
TOP3A	EXO1	0.988
EXO1	MUS81	0.988
BRCA2	FANCG	0.988
CHEK1	RPA2	0.987
FANCA	FANCM	0.987
FANCM	FANCE	0.987
BRCA1	CHEK1	0.987
DNA2	BLM	0.987
RAD52	WRN	0.987
RAD51	RAD51AP1	0.987
RMI1	MUS81	0.987
CHEK1	RPA1	0.987
BRCA1	EXO1	0.987
RAD51	ERCC1	0.986
FANCG	FANCM	0.986
DNA2	ATR	0.986
FANCF	FANCM	0.986
TOP3A	WRN	0.986
RAD51	RPA1	0.986
TOP3A	DNA2	0.986
FANCC	FANCM	0.986
EME1	RAD51	0.986
ATM	HUS1	0.986
RAD51	ATR	0.986
RAD52	ATR	0.986
RAD51	TOPBP1	0.986
CHEK1	RFC4	0.986
DNA2	ATM	0.986
DNA2	RMI1	0.986
EME1	FANCM	0.985
RAD52	DNA2	0.985
RAD51	WRN	0.985
RAD17	EXO1	0.985
TOP3A	RAD52	0.985
EXO1	RMI1	0.985
RAD51	MRE11A	0.985
EME1	ERCC4	0.985
RAD51AP1	POLE2	0.985
RFC4	EXO1	0.985
TOP3A	RAD51	0.985
TIPIN	TOPBP1	0.984
C19orf40	FANCL	0.984
RAD51	RPA2	0.984
POLD1	RPA1	0.984
DNA2	MUS81	0.983
RAD52	ERCC1	0.983
EXO1	RAD51AP1	0.983
EXO1	MRE11A	0.983
XRCC3	ATM	0.983
XRCC3	MUS81	0.983
BRCA2	EXO1	0.982
BLM	RMI1	0.982
RAD51	MSH5	0.982
C19orf40	FANCG	0.982
RAD52	RPA1	0.982
C19orf40	FANCF	0.982
RFC4	TOPBP1	0.982
BRCA1	FANCA	0.982
RFC4	RPA1	0.982
RMI1	FANCM	0.982
EXO1	ERCC1	0.982
BLM	MUS81	0.982
RAD17	RFC4	0.981
RAD17	RAD51	0.981
CHEK1	BRCA2	0.981
BRCA2	MLH1	0.981
FANCM	ERCC1	0.981
TOP3A	FANCM	0.981
RFC4	TIPIN	0.981
RPA1	RFC2	0.981
C19orf40	FANCC	0.981
EME1	BLM	0.98
CHEK1	DNA2	0.98
POLD1	RFC4	0.98
RAD17	RAD52	0.98
MUS81	WRN	0.98
RMI1	WRN	0.98
ATM	ERCC1	0.98
ATR	HUS1	0.98
RAD52	BLM	0.98
RAD51	MSH4	0.98
EME1	RMI1	0.98
C19orf40	EME1	0.98
C19orf40	FANCE	0.98
GEN1	RMI2	0.979
DNA2	TOPBP1	0.979
XRCC3	MRE11A	0.979
TOPBP1	RPA1	0.979
HUS1	RFC2	0.979
C19orf40	MUS81	0.979
RAD52	MRE11A	0.979
TIMELESS	TOPBP1	0.978
RAD50	ATM	0.978
XRCC3	WRN	0.978
BLM	ATR	0.978
RAD17	TIPIN	0.978
RPA2	RAD52	0.978
RAD51	RMI2	0.978
BLM	ATM	0.978
XRCC3	EXO1	0.978
RFC4	POLE	0.978
RAD51	ERCC4	0.978
MUS81	ATM	0.978
WRN	TOPBP1	0.977
RAD51	RMI1	0.977
BLM	MLH1	0.977
EXO1	POLE2	0.977
BRCA1	RAD52	0.977
BRCA2	ATR	0.977
DNA2	GEN1	0.977
POLD1	PCNA	0.977
EME1	RMI2	0.976
EXO1	RMI2	0.976
BLM	FANCM	0.976
FANCG	ERCC1	0.976
ATR	FANCM	0.976
POLD1	EXO1	0.976
RAD52	RMI1	0.976
EXO1	TOPBP1	0.975
XRCC3	EME1	0.975
EXO1	RPA1	0.975
ATR	MRE11A	0.975
ATR	RPA1	0.975
GEN1	RMI1	0.975
BRCA2	BRIP1	0.975
TOP3A	RMI2	0.975
BRCA1	DNA2	0.975
EXO1	ERCC4	0.975
WRN	ERCC1	0.975
BRCA1	TOPBP1	0.975
TOP3A	EME1	0.974
ATM	RPA1	0.974
RPA2	EXO1	0.974
RTEL1	WRN	0.974
RPA2	TIPIN	0.974
RPA2	DNA2	0.974
XRCC3	BLM	0.974
CHEK1	MRE11A	0.973
BRCA2	WRN	0.973
DNA2	RPA1	0.973
RPA2	ATR	0.973
C19orf40	ERCC4	0.973
CHEK1	FANCE	0.973
FANCA	MUS81	0.973
BRCA2	MUS81	0.973
RAD51	PCNA	0.973
BLM	TOPBP1	0.973
RAD51	RAD50	0.972
RAD51	HUS1	0.972
POLD1	DNA2	0.972
XRCC3	BRCA1	0.972
RAD51	BRIP1	0.972
BRCA1	BRIP1	0.972
BLM	RPA1	0.972
RFC4	RAD51AP1	0.972
TIPIN	HUS1	0.972
PCNA	POLE	0.972
PCNA	EXO1	0.972
TOP3A	GEN1	0.972
ATM	MLH1	0.972
TOP3A	MSH4	0.971
RAD52	ERCC4	0.971
DNA2	MRE11A	0.971
BRCA2	DNA2	0.971
TOP3A	ATR	0.971
RAD50	ATR	0.971
TIMELESS	ATR	0.971
RAD52	UBE2I	0.97
BRCA2	MRE11A	0.97
TIMELESS	BLM	0.97
PCNA	WRN	0.97
ATR	WRN	0.97
BRCA1	ATR	0.97
BLM	ERCC1	0.97
BRCA1	ERCC1	0.97
DNA2	POLE	0.97
CHEK1	WRN	0.97
RAD50	RAD52	0.97
TOP3A	FANCF	0.97
ATR	ERCC4	0.969
FANCA	BLM	0.969
RAD51	GEN1	0.969
PCNA	POLE2	0.969
RAD51	RTEL1	0.969
BRCA1	WRN	0.969
BRCA1	RFC4	0.969
TOP3A	FANCE	0.969
BLM	ERCC4	0.969
POLD1	RAD51	0.969
RAD17	RPA1	0.969
BRCA1	FANCC	0.969
EME1	WRN	0.968
TOP3A	MLH1	0.968
BRCA1	FANCL	0.968
C19orf40	ERCC1	0.968
RAD17	BLM	0.968
RPA2	TOPBP1	0.968
XRCC3	TOP3A	0.968
BLM	MRE11A	0.968
XRCC3	GEN1	0.968
EME1	FANCA	0.968
ATR	TIPIN	0.968
MRE11A	WRN	0.967
RAD17	WRN	0.967
RMI2	MUS81	0.967
MRE11A	MUS81	0.967
RTEL1	BLM	0.967
BRCA1	MRE11A	0.967
RMI2	RAD51AP1	0.967
RPA1	ERCC1	0.967
RAD50	EXO1	0.966
RAD17	RPA2	0.966
TIMELESS	ATM	0.966
CHEK1	FANCA	0.966
TOP3A	ATM	0.966
RFC4	ATM	0.966
MRE11A	ERCC4	0.966
RFC4	BLM	0.966
ATM	RFC2	0.966
BRIP1	RPA1	0.966
FANCG	BLM	0.966
ERCC4	ATM	0.965
BRCA1	FANCF	0.965
CHEK1	RMI2	0.965
EXO1	HUS1	0.965
GEN1	WRN	0.965
TIMELESS	RAD17	0.965
C19orf40	RMI1	0.965
TIMELESS	RFC4	0.965
BRCA1	FANCG	0.965
RFC4	RPA2	0.965
FANCA	ERCC1	0.965
BLM	TIPIN	0.965
ATM	TIPIN	0.965
UBE2I	WRN	0.965
RTEL1	DNA2	0.964
TOP3A	FANCG	0.964
BRCA2	BLM	0.964
TOPBP1	RFC2	0.964
XRCC3	FANCG	0.964
EME1	DNA2	0.964
TOP3A	ERCC1	0.964
TOP3A	BRCA2	0.964
TIMELESS	WRN	0.964
TOP3A	FANCA	0.964
HUS1	RPA1	0.964
BLM	MSH4	0.964
EXO1	TIPIN	0.963
XRCC3	RMI2	0.963
BLM	RMI2	0.963
TOP3A	FANCC	0.963
RAD17	MRE11A	0.963
TIPIN	RFC2	0.963
POLD1	RFC2	0.963
EXO1	BRIP1	0.962
POLE	RPA1	0.962
WRN	RPA1	0.962
TIMELESS	HUS1	0.962
FANCL	MUS81	0.962
RAD17	BRCA1	0.962
ERCC4	FANCC	0.962
MUS81	BRIP1	0.962
MSH5	BLM	0.962
BLM	FANCF	0.962
RPA2	RFC2	0.962
BLM	GEN1	0.962
XRCC3	RAD50	0.961
FANCF	ERCC4	0.961
FANCA	ERCC4	0.961
RAD51	MLH3	0.961
BLM	FANCC	0.961
RPA2	BLM	0.961
FANCG	ERCC4	0.961
BLM	POLE2	0.961
RPA2	ERCC1	0.961
EXO1	POLE	0.961
WRN	BRIP1	0.961
PCNA	RAD51AP1	0.961
DNA2	RMI2	0.961
ATR	RMI1	0.961
TIMELESS	DNA2	0.96
BLM	FANCE	0.96
ATR	ERCC1	0.96
EXO1	RTEL1	0.96
RFC4	RAD51	0.96
POLD1	WRN	0.96
C19orf40	TOP3A	0.96
EME1	BRCA2	0.96
BRCA1	RAD51AP1	0.96
BRCA2	TOPBP1	0.959
BRCA1	BLM	0.959
BRCA1	FANCE	0.959
TIMELESS	EXO1	0.959
RAD17	DNA2	0.959
RAD17	BRCA2	0.959
RFC4	RMI2	0.959
TOP3A	MRE11A	0.959
BRCA1	RPA2	0.959
TOP3A	MSH5	0.959
RMI2	WRN	0.959
RPA1	POLE2	0.959
FANCL	ERCC1	0.959
TOP3A	ERCC4	0.959
RAD52	TOPBP1	0.959
BRCA1	MUS81	0.959
XRCC3	RPA1	0.959
POLE	WRN	0.958
TOPBP1	BRIP1	0.958
FANCM	RPA1	0.958
RMI1	RPA1	0.958
RPA2	WRN	0.958
WRN	HUS1	0.958
DNA2	POLE2	0.958
ERCC4	FANCE	0.958
XRCC3	DNA2	0.958
BRCA2	RAD51AP1	0.958
RFC4	DNA2	0.958
FANCL	ERCC4	0.958
BRCA1	POLE	0.958
RFC4	HUS1	0.958
EME1	ATM	0.958
PCNA	UBE2I	0.958
DNA2	BRIP1	0.958
MRE11A	HUS1	0.957
CHEK1	RFC2	0.957
RMI1	ERCC4	0.957
ATM	BRIP1	0.957
ERCC4	WRN	0.956
BLM	BRIP1	0.956
RMI2	FANCM	0.956
BRCA1	HUS1	0.956
BRCA1	EME1	0.956
RAD17	ERCC1	0.956
UBE2I	BLM	0.956
BRCA1	RFC2	0.955
TIMELESS	RPA1	0.955
POLD1	RPA2	0.955
DNA2	ERCC1	0.955
FANCC	ERCC1	0.955
WRN	TIPIN	0.955
EXO1	RFC2	0.955
DNA2	TIPIN	0.955
MRE11A	RPA1	0.955
RTEL1	RMI1	0.955
TIPIN	RPA1	0.955
RAD50	MUS81	0.955
BLM	RAD51AP1	0.955
BRCA2	GEN1	0.955
TIMELESS	RFC2	0.954
BRCA1	ERCC4	0.954
MRE11A	GEN1	0.954
RAD51	POLE2	0.954
RAD50	BLM	0.954
RAD50	DNA2	0.954
FANCL	EME1	0.954
FANCL	BLM	0.954
BLM	RFC2	0.954
BRCA2	POLE	0.954
MSH5	MSH4	0.953
EME1	FANCG	0.953
RAD51	POLE	0.953
BLM	HUS1	0.953
ERCC4	RPA1	0.953
C19orf40	BLM	0.953
MRE11A	ERCC1	0.953
EME1	BRIP1	0.953
RPA1	MLH1	0.953
POLD1	MRE11A	0.953
POLD1	ERCC4	0.953
RFC4	WRN	0.953
TOP3A	FANCL	0.952
XRCC3	RMI1	0.952
XRCC3	RFC2	0.952
BRCA1	POLE2	0.952
RAD17	RAD50	0.952
FANCF	ERCC1	0.952
RAD17	ERCC4	0.952
GEN1	ATM	0.952
TOP3A	TOPBP1	0.952
DNA2	HUS1	0.952
DNA2	ERCC4	0.952
TOP3A	RTEL1	0.952
POLD1	BLM	0.952
PCNA	BLM	0.951
MRE11A	RMI1	0.951
FANCG	MUS81	0.951
BRCA1	RAD50	0.951
BRCA1	POLD1	0.951
ATR	ATM	0.951
EME1	FANCC	0.951
POLD1	BRCA2	0.95
RMI1	ATM	0.95
BLM	WRN	0.95
TOP3A	RPA1	0.95
MRE11A	POLE	0.95
MLH3	BLM	0.95
POLE	ERCC4	0.95
RPA2	HUS1	0.949
BLM	POLE	0.949
CHEK1	FANCC	0.949
MUS81	FANCC	0.949
BRCA2	RMI1	0.949
RMI1	TOPBP1	0.949
CHEK1	FANCG	0.949
ERCC4	BRIP1	0.948
POLE2	RFC2	0.948
WRN	RFC2	0.948
BRCA2	MLH3	0.948
EME1	FANCE	0.948
POLE	ATM	0.948
RMI1	ERCC1	0.948
BRCA2	HUS1	0.947
RFC4	FANCG	0.947
RFC4	ATR	0.947
XRCC3	RAD51	0.947
CHEK1	BRIP1	0.947
TOP3A	MLH3	0.947
BRIP1	ERCC1	0.947
TOP3A	RFC2	0.947
BRCA2	RPA1	0.946
ERCC4	HUS1	0.946
POLE	RFC2	0.946
DNA2	RFC2	0.946
C19orf40	RPA1	0.946
RPA2	POLE	0.946
BRCA1	GEN1	0.946
PCNA	MLH1	0.946
FANCF	RMI1	0.946
ERCC4	TOPBP1	0.946
FANCF	MUS81	0.946
BRCA1	RMI1	0.946
BRCA2	RPA2	0.946
C19orf40	RPA2	0.946
CHEK1	FANCL	0.945
C19orf40	ATR	0.945
TOP3A	RAD17	0.945
CHEK1	RMI1	0.945
MUS81	FANCE	0.945
TOP3A	RAD50	0.945
RPA2	ERCC4	0.945
BRCA1	RPA1	0.945
RPA2	FANCM	0.945
UBE2I	ATM	0.945
RMI2	TOPBP1	0.944
BRIP1	POLE2	0.944
HUS1	ERCC1	0.944
RAD52	RMI2	0.944
POLD1	ATM	0.944
EME1	FANCF	0.944
TIMELESS	TOP3A	0.944
RAD50	WRN	0.944
TOPBP1	ERCC1	0.944
CHEK1	FANCF	0.943
EXO1	GEN1	0.943
BRCA2	RTEL1	0.943
BRCA1	RTEL1	0.943
BRCA1	UBE2I	0.943
RAD52	HUS1	0.943
PCNA	MRE11A	0.943
RMI2	RPA1	0.943
RPA2	POLE2	0.943
MLH3	ATM	0.942
TOP3A	POLD1	0.942
FANCA	TOPBP1	0.942
FANCE	ERCC1	0.942
PCNA	DNA2	0.942
POLD1	ERCC1	0.942
BRIP1	MLH1	0.941
XRCC3	BRIP1	0.941
BRCA1	MSH4	0.941
RTEL1	ATM	0.941
MLH3	MLH1	0.941
FANCL	RMI1	0.941
RAD50	RMI1	0.941
BRCA1	TIPIN	0.941
TOP3A	RFC4	0.941
MRE11A	TOPBP1	0.941
TIMELESS	POLE	0.94
TOP3A	BRCA1	0.94
RTEL1	RMI2	0.94
XRCC3	RAD51AP1	0.94
RFC4	FANCE	0.939
RAD50	GEN1	0.939
RAD51	RFC2	0.939
ATM	MSH4	0.939
RMI1	FANCC	0.939
DNA2	RAD51AP1	0.939
TOP3A	CHEK1	0.939
XRCC3	POLD1	0.939
TOP3A	PCNA	0.938
RAD50	ERCC1	0.938
RAD52	RFC2	0.938
ATR	RFC2	0.938
POLD1	RTEL1	0.938
MSH5	ATM	0.938
XRCC3	RTEL1	0.938
ERCC4	FANCM	0.938
XRCC3	RPA2	0.937
RMI1	RAD51AP1	0.937
RAD50	RFC2	0.937
RMI1	FANCE	0.937
FANCA	RMI1	0.937
MRE11A	BRIP1	0.936
EME1	MRE11A	0.936
TIMELESS	BRCA1	0.936
RFC4	RMI1	0.936
POLE	BRIP1	0.936
GEN1	BRIP1	0.936
RFC4	RAD50	0.936
BRCA2	POLE2	0.935
RMI2	POLE2	0.935
ATR	BRIP1	0.935
FANCG	RMI1	0.935
MRE11A	RAD51AP1	0.935
BRCA1	RMI2	0.935
RFC4	FANCA	0.935
RAD52	MUS81	0.934
RFC4	MRE11A	0.934
TIMELESS	RPA2	0.934
BRCA2	RAD50	0.934
UBE2I	RPA1	0.934
BRCA1	PCNA	0.934
RPA2	RMI1	0.934
RPA2	BRIP1	0.933
RFC4	BRIP1	0.933
BRCA2	MSH5	0.933
FANCC	RPA1	0.933
BRCA1	MSH5	0.932
FANCA	ATR	0.932
TIMELESS	RMI2	0.932
POLE	ERCC1	0.932
RAD50	RPA1	0.932
FANCA	RPA2	0.931
CHEK1	RAD50	0.931
BRCA2	RMI2	0.931
RMI1	TIPIN	0.931
FANCG	RFC2	0.931
EME1	RAD51AP1	0.931
XRCC3	POLE	0.931
RAD17	RMI1	0.931
FANCE	RFC2	0.931
RFC4	RAD52	0.931
RFC4	FANCF	0.931
RFC2	ERCC1	0.931
MRE11A	RFC2	0.93
RMI2	ERCC1	0.93
FANCL	TOPBP1	0.93
MSH5	RPA1	0.93
RPA2	MRE11A	0.93
FANCA	RFC2	0.93
RTEL1	MRE11A	0.93
XRCC3	PCNA	0.929
FANCA	RPA1	0.929
RPA2	MLH1	0.929
RFC4	BRCA2	0.929
POLD1	BRIP1	0.929
HUS1	FANCE	0.929
PCNA	RMI2	0.929
BRCA2	MSH4	0.929
MSH4	RPA1	0.929
RTEL1	RAD51AP1	0.929
POLD1	RAD51AP1	0.929
RPA2	RMI2	0.929
TOP3A	TIPIN	0.928
TOP3A	RPA2	0.928
WRN	POLE2	0.928
RPA2	FANCC	0.928
RFC4	FANCC	0.928
FANCF	RFC2	0.928
PCNA	ATM	0.926
FANCG	TOPBP1	0.926
FANCC	RFC2	0.926
RAD17	FANCA	0.926
FANCG	RPA2	0.926
TOPBP1	FANCE	0.926
FANCC	TOPBP1	0.925
POLE	RAD51AP1	0.925
BRCA2	RFC2	0.925
TIPIN	BRIP1	0.924
RAD17	FANCE	0.924
RAD50	HUS1	0.924
TIMELESS	BRIP1	0.924
RAD17	FANCC	0.924
RPA2	RAD51AP1	0.923
RAD50	POLE	0.923
BRIP1	RAD51AP1	0.923
FANCG	RPA1	0.923
RMI1	POLE2	0.923
RPA2	FANCE	0.923
RMI1	BRIP1	0.922
ATM	RAD51AP1	0.922
TOP3A	BRIP1	0.922
MLH3	RPA1	0.922
RMI2	BRIP1	0.922
RAD52	BRIP1	0.922
PCNA	ERCC4	0.922
WRN	RAD51AP1	0.922
TOP3A	POLE	0.921
FANCF	RPA1	0.921
RPA2	MSH4	0.921
EME1	RAD50	0.921
RMI2	ATM	0.921
FANCF	TOPBP1	0.921
PCNA	RAD50	0.921
RPA2	FANCF	0.92
RAD17	FANCL	0.92
RPA1	FANCE	0.92
POLD1	RAD50	0.92
ERCC4	RFC2	0.92
RAD17	BRIP1	0.919
ATR	FANCC	0.919
ATR	RMI2	0.919
TIMELESS	MRE11A	0.919
RAD51AP1	RFC2	0.919
FANCL	HUS1	0.919
POLD1	RMI1	0.918
FANCL	ATR	0.918
FANCA	HUS1	0.918
BRCA2	PCNA	0.918
RAD50	ERCC4	0.918
RAD50	TOPBP1	0.918
FANCG	HUS1	0.917
RAD17	FANCG	0.917
PCNA	RMI1	0.917
RMI2	TIPIN	0.917
RAD17	FANCF	0.917
PCNA	BRIP1	0.917
GEN1	MUS81	0.917
POLE	RMI1	0.916
POLD1	RMI2	0.916
ERCC4	POLE2	0.916
XRCC3	POLE2	0.916
POLE	RMI2	0.915
TIMELESS	RMI1	0.915
ATM	POLE2	0.915
FANCL	RPA2	0.915
RMI1	HUS1	0.915
BRIP1	RFC2	0.915
BRIP1	HUS1	0.914
FANCG	ATR	0.914
RAD50	RPA2	0.914
MRE11A	TIPIN	0.914
XRCC3	RFC4	0.914
MLH1	ERCC1	0.914
MSH5	RPA2	0.914
TOP3A	HUS1	0.913
FANCC	HUS1	0.913
RTEL1	BRIP1	0.913
ATR	FANCF	0.913
FANCF	HUS1	0.912
FANCL	RPA1	0.912
POLD1	MLH1	0.912
RFC4	ERCC4	0.912
GEN1	RAD51AP1	0.911
ATR	FANCE	0.911
RMI1	RFC2	0.911
RMI2	HUS1	0.911
ERCC4	RMI2	0.911
RFC4	ERCC1	0.911
FANCL	RFC4	0.91
PCNA	ERCC1	0.91
TOP3A	POLE2	0.91
RPA1	RAD51AP1	0.91
MUS81	RAD51AP1	0.908
MRE11A	POLE2	0.908
POLE2	ERCC1	0.906
UBE2I	MRE11A	0.906
RAD17	RMI2	0.906
MRE11A	RMI2	0.906
RMI2	RFC2	0.906
RAD50	TIPIN	0.904
RPA2	MLH3	0.904
TIMELESS	RAD50	0.903
FANCL	RFC2	0.903
RAD50	POLE2	0.902
RAD50	RTEL1	0.902
RAD50	BRIP1	0.902
RAD50	UBE2I	0.902
TOP3A	RAD51AP1	0.901
RAD50	RAD51AP1	0.9
RAD50	RMI2	0.9

Gene Ontology Semantic Similarity

Download Tab separated file

#	5424 (POLD1)	5984 (RFC4)	5426 (POLE)	146956 (EME1)	5888 (RAD51)	10111 (RAD50)	1111 (CHEK1)	6118 (RPA2)	9156 (EXO1)	672 (BRCA1)	5111 (PCNA)	91442 (C19orf40)	5884 (RAD17)	2175 (FANCA)	80010 (RMI1)	7156 (TOP3A)	4438 (MSH4)	2189 (FANCG)	2176 (FANCC)	472 (ATM)	27030 (MLH3)	8914 (TIMELESS)	2188 (FANCF)	55120 (FANCL)	2072 (ERCC4)	675 (BRCA2)	80198 (MUS81)	11073 (TOPBP1)	4439 (MSH5)	7486 (WRN)	5893 (RAD52)	4361 (MRE11A)	1763 (DNA2)	7517 (XRCC3)	545 (ATR)	57697 (FANCM)	10635 (RAD51AP1)	54962 (TIPIN)	641 (BLM)	6117 (RPA1)	348654 (GEN1)	3364 (HUS1)	51750 (RTEL1)	83990 (BRIP1)	7329 (UBE2I)	5427 (POLE2)	2178 (FANCE)	5982 (RFC2)	4292 (MLH1)	2067 (ERCC1)
5424 (POLD1)	1.00	0.51	0.97	0.51	0.66	0.67	0.52	0.72	0.71	0.66	0.68	0.62	0.67	1.00	1.00	0.45	0.65	0.70	1.00	0.57	0.53	0.70	0.48	0.49	0.73	0.61	0.49	0.56	0.61	0.51	0.73	0.70	0.50	0.59	0.51	0.62	0.69	0.70	0.43	0.71	0.64	1.00	0.44	0.63	0.63	0.66	0.48	0.51	0.69	0.73
5984 (RFC4)	0.51	1.00	0.51	0.44	0.71	0.53	0.41	0.60	0.36	0.58	0.57	0.56	0.84	1.00	1.00	0.47	0.65	0.64	1.00	0.49	0.73	0.67	0.51	0.47	0.56	0.57	0.39	0.66	0.66	0.47	0.67	0.52	0.60	0.51	0.46	0.56	0.60	0.67	0.52	0.55	0.31	1.00	0.65	0.74	0.58	0.49	0.48	1.00	0.71	0.57
5426 (POLE)	0.97	0.51	1.00	0.51	0.65	0.64	0.53	0.69	0.67	0.65	0.65	0.66	0.68	1.00	1.00	0.46	0.61	0.64	1.00	0.59	0.53	0.67	0.50	0.50	0.68	0.59	0.48	0.59	0.56	0.48	0.71	0.66	0.45	0.58	0.52	0.66	0.68	0.67	0.41	0.67	0.62	1.00	0.45	0.60	0.62	0.71	0.48	0.51	0.68	0.69
146956 (EME1)	0.51	0.44	0.51	1.00	0.50	0.54	0.41	0.48	0.61	0.52	0.53	0.54	0.49	1.00	1.00	0.47	0.38	0.51	1.00	0.48	0.47	0.52	0.50	0.47	0.76	0.52	0.97	0.64	0.38	0.35	0.53	0.68	0.55	0.84	0.46	0.54	0.46	0.52	0.29	0.41	0.59	1.00	0.46	0.45	0.55	0.48	0.48	0.44	0.53	0.72
5888 (RAD51)	0.66	0.71	0.65	0.50	1.00	0.66	0.51	0.73	0.58	0.68	0.71	0.60	0.70	1.00	1.00	0.55	0.82	0.61	1.00	0.55	0.69	0.64	0.54	0.54	0.68	0.67	0.48	0.62	0.81	0.61	0.71	0.67	0.68	0.55	0.51	0.60	0.69	0.64	0.67	0.66	0.47	1.00	0.74	0.72	0.65	0.52	0.48	0.71	0.81	0.67
10111 (RAD50)	0.67	0.53	0.64	0.54	0.66	1.00	0.48	0.68	0.68	0.62	0.57	0.40	0.50	1.00	1.00	0.39	0.65	0.56	1.00	0.48	0.56	0.60	0.42	0.42	0.78	0.56	0.55	0.46	0.60	0.66	0.64	0.84	0.71	0.58	0.45	0.40	0.62	0.60	0.63	0.69	0.64	1.00	0.51	0.70	0.56	0.41	0.48	0.53	0.62	0.77
1111 (CHEK1)	0.52	0.41	0.53	0.41	0.51	0.48	1.00	0.46	0.33	0.55	0.49	0.48	0.45	1.00	1.00	0.49	0.38	0.46	1.00	0.84	0.42	0.47	0.53	0.56	0.46	0.52	0.38	0.56	0.38	0.31	0.49	0.42	0.34	0.42	0.86	0.48	0.44	0.47	0.29	0.40	0.25	1.00	0.43	0.43	0.61	0.61	0.48	0.41	0.48	0.48
6118 (RPA2)	0.72	0.60	0.69	0.48	0.73	0.68	0.46	1.00	0.55	0.77	0.73	0.55	0.63	1.00	1.00	0.50	0.74	0.80	1.00	0.51	0.66	0.82	0.51	0.56	0.74	0.72	0.45	0.60	0.71	0.46	0.85	0.61	0.53	0.63	0.50	0.55	0.83	0.82	0.48	0.91	0.50	1.00	0.52	0.76	0.70	0.52	0.48	0.60	0.77	0.77
9156 (EXO1)	0.71	0.36	0.67	0.61	0.58	0.68	0.33	0.55	1.00	0.53	0.55	0.40	0.44	1.00	1.00	0.35	0.49	0.42	1.00	0.38	0.42	0.45	0.36	0.34	0.74	0.45	0.62	0.38	0.45	0.57	0.50	0.81	0.66	0.56	0.33	0.40	0.49	0.45	0.41	0.49	0.80	1.00	0.32	0.43	0.47	0.31	0.48	0.36	0.53	0.71
672 (BRCA1)	0.66	0.58	0.65	0.52	0.68	0.62	0.55	0.77	0.53	1.00	0.69	0.57	0.61	1.00	1.00	0.55	0.66	0.68	1.00	0.57	0.60	0.71	0.63	0.72	0.68	0.70	0.50	0.63	0.62	0.48	0.75	0.60	0.52	0.60	0.56	0.57	0.73	0.71	0.49	0.69	0.45	1.00	0.54	0.67	0.77	0.57	0.48	0.58	0.68	0.68
5111 (PCNA)	0.68	0.57	0.65	0.53	0.71	0.57	0.49	0.73	0.55	0.69	1.00	0.64	0.66	1.00	1.00	0.53	0.64	0.67	1.00	0.56	0.58	0.66	0.56	0.54	0.66	0.63	0.50	0.63	0.63	0.51	0.70	0.58	0.50	0.58	0.59	0.64	0.66	0.66	0.46	0.66	0.42	1.00	0.57	0.63	0.65	0.54	0.48	0.57	0.74	0.66
91442 (C19orf40)	0.62	0.56	0.66	0.54	0.60	0.40	0.48	0.55	0.40	0.57	0.64	1.00	0.84	1.00	1.00	0.58	0.44	0.70	1.00	0.63	0.57	0.71	0.62	0.57	0.53	0.59	0.47	0.82	0.45	0.34	0.67	0.43	0.32	0.57	0.55	1.00	0.58	0.71	0.28	0.49	0.25	1.00	0.57	0.59	0.62	0.66	0.48	0.56	0.73	0.54
5884 (RAD17)	0.67	0.84	0.68	0.49	0.70	0.50	0.45	0.63	0.44	0.61	0.66	0.84	1.00	1.00	1.00	0.52	0.58	0.71	1.00	0.58	0.65	0.74	0.55	0.52	0.58	0.61	0.43	0.72	0.58	0.46	0.72	0.49	0.48	0.57	0.51	0.84	0.65	0.74	0.45	0.60	0.32	1.00	0.61	0.69	0.61	0.57	0.48	0.84	0.77	0.60
2175 (FANCA)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.61	1.00	1.00	1.00	1.00	1.00	0.48	1.00	1.00	1.00
80010 (RMI1)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.61	1.00	1.00	1.00	1.00	1.00	0.48	1.00	1.00	1.00
7156 (TOP3A)	0.45	0.47	0.46	0.47	0.55	0.39	0.49	0.50	0.35	0.55	0.53	0.58	0.52	1.00	1.00	1.00	0.40	0.55	1.00	0.53	0.48	0.55	0.57	0.54	0.50	0.55	0.43	0.67	0.40	0.32	0.56	0.45	0.36	0.48	0.51	0.58	0.49	0.55	0.30	0.43	0.27	1.00	0.48	0.48	0.60	0.54	0.48	0.47	0.54	0.50
4438 (MSH4)	0.65	0.65	0.61	0.38	0.82	0.65	0.38	0.74	0.49	0.66	0.64	0.44	0.58	1.00	1.00	0.40	1.00	0.70	1.00	0.43	0.67	0.73	0.42	0.40	0.68	0.61	0.36	0.51	0.99	0.57	0.75	0.61	0.65	0.53	0.41	0.44	0.72	0.73	0.68	0.71	0.46	1.00	0.66	0.78	0.59	0.40	0.48	0.65	0.71	0.70
2189 (FANCG)	0.70	0.64	0.64	0.51	0.61	0.56	0.46	0.80	0.42	0.68	0.67	0.70	0.71	1.00	1.00	0.55	0.70	1.00	1.00	0.55	0.65	0.94	0.59	0.54	0.70	0.67	0.44	0.79	0.68	0.39	0.89	0.51	0.40	0.66	0.53	0.70	0.82	0.94	0.40	0.82	0.39	1.00	0.55	0.77	0.67	0.62	0.48	0.64	0.69	0.75
2176 (FANCC)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.61	1.00	1.00	1.00	1.00	1.00	0.48	1.00	1.00	1.00
472 (ATM)	0.57	0.49	0.59	0.48	0.55	0.48	0.84	0.51	0.38	0.57	0.56	0.63	0.58	1.00	1.00	0.53	0.43	0.55	1.00	1.00	0.50	0.55	0.56	0.57	0.52	0.55	0.45	0.62	0.44	0.36	0.55	0.43	0.36	0.50	0.81	0.63	0.51	0.55	0.31	0.46	0.27	1.00	0.50	0.50	0.61	0.62	0.48	0.49	0.57	0.50
27030 (MLH3)	0.53	0.73	0.53	0.47	0.69	0.56	0.42	0.66	0.42	0.60	0.58	0.57	0.65	1.00	1.00	0.48	0.67	0.65	1.00	0.50	1.00	0.69	0.52	0.48	0.59	0.58	0.42	0.67	0.65	0.52	0.69	0.55	0.67	0.53	0.47	0.57	0.67	0.69	0.57	0.63	0.36	1.00	0.60	0.74	0.59	0.51	0.48	0.73	0.78	0.60
8914 (TIMELESS)	0.70	0.67	0.67	0.52	0.64	0.60	0.47	0.82	0.45	0.71	0.66	0.71	0.74	1.00	1.00	0.55	0.73	0.94	1.00	0.55	0.69	1.00	0.60	0.55	0.71	0.69	0.45	0.80	0.68	0.42	0.95	0.54	0.42	0.71	0.54	0.71	0.90	1.00	0.43	0.84	0.43	1.00	0.56	0.82	0.68	0.63	0.48	0.67	0.72	0.76
2188 (FANCF)	0.48	0.51	0.50	0.50	0.54	0.42	0.53	0.51	0.36	0.63	0.56	0.62	0.55	1.00	1.00	0.57	0.42	0.59	1.00	0.56	0.52	0.60	1.00	0.84	0.52	0.57	0.45	0.71	0.43	0.33	0.59	0.45	0.37	0.51	0.55	0.62	0.52	0.60	0.31	0.45	0.27	1.00	0.51	0.52	0.67	0.60	1.00	0.51	0.56	0.52
55120 (FANCL)	0.49	0.47	0.50	0.47	0.54	0.42	0.56	0.56	0.34	0.72	0.54	0.57	0.52	1.00	1.00	0.54	0.40	0.54	1.00	0.57	0.48	0.55	0.84	1.00	0.49	0.56	0.43	0.65	0.41	0.31	0.55	0.44	0.35	0.48	0.56	0.57	0.49	0.55	0.29	0.44	0.26	1.00	0.48	0.49	0.72	0.60	0.48	0.47	0.54	0.49
2072 (ERCC4)	0.73	0.56	0.68	0.76	0.68	0.78	0.46	0.74	0.74	0.68	0.66	0.53	0.58	1.00	1.00	0.50	0.68	0.70	1.00	0.52	0.59	0.71	0.52	0.49	1.00	0.68	0.76	0.63	0.64	0.52	0.78	0.84	0.69	0.76	0.48	0.53	0.72	0.71	0.50	0.74	0.73	1.00	0.49	0.67	0.62	0.50	0.48	0.56	0.67	0.96
675 (BRCA2)	0.61	0.57	0.59	0.52	0.67	0.56	0.52	0.72	0.45	0.70	0.63	0.59	0.61	1.00	1.00	0.55	0.61	0.67	1.00	0.55	0.58	0.69	0.57	0.56	0.68	1.00	0.48	0.71	0.58	0.42	0.77	0.56	0.44	0.59	0.54	0.59	0.71	0.69	0.44	0.71	0.41	1.00	0.54	0.63	0.65	0.57	0.48	0.57	0.66	0.69
80198 (MUS81)	0.49	0.39	0.48	0.97	0.48	0.55	0.38	0.45	0.62	0.50	0.50	0.47	0.43	1.00	1.00	0.43	0.36	0.44	1.00	0.45	0.42	0.45	0.45	0.43	0.76	0.48	1.00	0.56	0.36	0.35	0.48	0.68	0.55	0.83	0.42	0.47	0.42	0.45	0.28	0.38	0.60	1.00	0.41	0.40	0.52	0.41	0.48	0.39	0.49	0.71
11073 (TOPBP1)	0.56	0.66	0.59	0.64	0.62	0.46	0.56	0.60	0.38	0.63	0.63	0.82	0.72	1.00	1.00	0.67	0.51	0.79	1.00	0.62	0.67	0.80	0.71	0.65	0.63	0.71	0.56	1.00	0.53	0.33	0.79	0.52	0.38	0.67	0.63	0.82	0.67	0.80	0.32	0.56	0.30	1.00	0.65	0.68	0.67	0.75	0.48	0.66	0.66	0.63
4439 (MSH5)	0.61	0.66	0.56	0.38	0.81	0.60	0.38	0.71	0.45	0.62	0.63	0.45	0.58	1.00	1.00	0.40	0.99	0.68	1.00	0.44	0.65	0.68	0.43	0.41	0.64	0.58	0.36	0.53	1.00	0.53	0.70	0.58	0.62	0.49	0.41	0.45	0.68	0.68	0.64	0.66	0.41	1.00	0.69	0.74	0.57	0.41	0.48	0.66	0.69	0.66
7486 (WRN)	0.51	0.47	0.48	0.35	0.61	0.66	0.31	0.46	0.57	0.48	0.51	0.34	0.46	1.00	1.00	0.32	0.57	0.39	1.00	0.36	0.52	0.42	0.33	0.31	0.52	0.42	0.35	0.33	0.53	1.00	0.45	0.68	0.71	0.44	0.34	0.34	0.42	0.42	0.88	0.43	0.54	1.00	0.48	0.59	0.42	0.29	0.48	0.47	0.63	0.50
5893 (RAD52)	0.73	0.67	0.71	0.53	0.71	0.64	0.49	0.85	0.50	0.75	0.70	0.67	0.72	1.00	1.00	0.56	0.75	0.89	1.00	0.55	0.69	0.95	0.59	0.55	0.78	0.77	0.48	0.79	0.70	0.45	1.00	0.60	0.48	0.71	0.54	0.67	0.92	0.95	0.48	0.88	0.49	1.00	0.57	0.82	0.69	0.61	0.48	0.67	0.77	0.80
4361 (MRE11A)	0.70	0.52	0.66	0.68	0.67	0.84	0.42	0.61	0.81	0.60	0.58	0.43	0.49	1.00	1.00	0.45	0.61	0.51	1.00	0.43	0.55	0.54	0.45	0.44	0.84	0.56	0.68	0.52	0.58	0.68	0.60	1.00	0.79	0.64	0.42	0.43	0.57	0.54	0.60	0.56	0.74	1.00	0.52	0.63	0.54	0.41	0.48	0.52	0.58	0.80
1763 (DNA2)	0.50	0.60	0.45	0.55	0.68	0.71	0.34	0.53	0.66	0.52	0.50	0.32	0.48	1.00	1.00	0.36	0.65	0.40	1.00	0.36	0.67	0.42	0.37	0.35	0.69	0.44	0.55	0.38	0.62	0.71	0.48	0.79	1.00	0.50	0.33	0.32	0.46	0.42	0.69	0.48	0.61	1.00	0.52	0.61	0.47	0.30	0.48	0.60	0.69	0.65
7517 (XRCC3)	0.59	0.51	0.58	0.84	0.55	0.58	0.42	0.63	0.56	0.60	0.58	0.57	0.57	1.00	1.00	0.48	0.53	0.66	1.00	0.50	0.53	0.71	0.51	0.48	0.76	0.59	0.83	0.67	0.49	0.44	0.71	0.64	0.50	1.00	0.47	0.57	0.64	0.71	0.41	0.59	0.62	1.00	0.48	0.60	0.60	0.50	0.48	0.51	0.60	0.74
545 (ATR)	0.51	0.46	0.52	0.46	0.51	0.45	0.86	0.50	0.33	0.56	0.59	0.55	0.51	1.00	1.00	0.51	0.41	0.53	1.00	0.81	0.47	0.54	0.55	0.56	0.48	0.54	0.42	0.63	0.41	0.34	0.54	0.42	0.33	0.47	1.00	0.55	0.49	0.54	0.29	0.44	0.25	1.00	0.48	0.48	0.60	0.61	0.48	0.46	0.62	0.48
57697 (FANCM)	0.62	0.56	0.66	0.54	0.60	0.40	0.48	0.55	0.40	0.57	0.64	1.00	0.84	1.00	1.00	0.58	0.44	0.70	1.00	0.63	0.57	0.71	0.62	0.57	0.53	0.59	0.47	0.82	0.45	0.34	0.67	0.43	0.32	0.57	0.55	1.00	0.58	0.71	0.28	0.49	0.25	1.00	0.57	0.59	0.62	0.66	0.48	0.56	0.73	0.54
10635 (RAD51AP1)	0.69	0.60	0.68	0.46	0.69	0.62	0.44	0.83	0.49	0.73	0.66	0.58	0.65	1.00	1.00	0.49	0.72	0.82	1.00	0.51	0.67	0.90	0.52	0.49	0.72	0.71	0.42	0.67	0.68	0.42	0.92	0.57	0.46	0.64	0.49	0.58	1.00	0.90	0.44	0.83	0.48	1.00	0.50	0.78	0.72	0.53	0.48	0.60	0.74	0.76
54962 (TIPIN)	0.70	0.67	0.67	0.52	0.64	0.60	0.47	0.82	0.45	0.71	0.66	0.71	0.74	1.00	1.00	0.55	0.73	0.94	1.00	0.55	0.69	1.00	0.60	0.55	0.71	0.69	0.45	0.80	0.68	0.42	0.95	0.54	0.42	0.71	0.54	0.71	0.90	1.00	0.43	0.84	0.43	1.00	0.56	0.82	0.68	0.63	0.48	0.67	0.72	0.76
641 (BLM)	0.43	0.52	0.41	0.29	0.67	0.63	0.29	0.48	0.41	0.49	0.46	0.28	0.45	1.00	1.00	0.30	0.68	0.40	1.00	0.31	0.57	0.43	0.31	0.29	0.50	0.44	0.28	0.32	0.64	0.88	0.48	0.60	0.69	0.41	0.29	0.28	0.44	0.43	1.00	0.46	0.45	1.00	0.57	0.65	0.42	0.27	0.48	0.52	0.63	0.48
6117 (RPA1)	0.71	0.55	0.67	0.41	0.66	0.69	0.40	0.91	0.49	0.69	0.66	0.49	0.60	1.00	1.00	0.43	0.71	0.82	1.00	0.46	0.63	0.84	0.45	0.44	0.74	0.71	0.38	0.56	0.66	0.43	0.88	0.56	0.48	0.59	0.44	0.49	0.83	0.84	0.46	1.00	0.48	1.00	0.44	0.75	0.63	0.45	0.48	0.55	0.74	0.78
348654 (GEN1)	0.64	0.31	0.62	0.59	0.47	0.64	0.25	0.50	0.80	0.45	0.42	0.25	0.32	0.61	0.61	0.27	0.46	0.39	0.61	0.27	0.36	0.43	0.27	0.26	0.73	0.41	0.60	0.30	0.41	0.54	0.49	0.74	0.61	0.62	0.25	0.25	0.48	0.43	0.45	0.48	1.00	0.61	0.25	0.41	0.37	0.24	0.28	0.31	0.42	0.69
3364 (HUS1)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.61	1.00	1.00	1.00	1.00	1.00	0.48	1.00	1.00	1.00
51750 (RTEL1)	0.44	0.65	0.45	0.46	0.74	0.51	0.43	0.52	0.32	0.54	0.57	0.57	0.61	1.00	1.00	0.48	0.66	0.55	1.00	0.50	0.60	0.56	0.51	0.48	0.49	0.54	0.41	0.65	0.69	0.48	0.57	0.52	0.52	0.48	0.48	0.57	0.50	0.56	0.57	0.44	0.25	1.00	1.00	0.76	0.58	0.51	0.48	0.65	0.64	0.49
83990 (BRIP1)	0.63	0.74	0.60	0.45	0.72	0.70	0.43	0.76	0.43	0.67	0.63	0.59	0.69	1.00	1.00	0.48	0.78	0.77	1.00	0.50	0.74	0.82	0.52	0.49	0.67	0.63	0.40	0.68	0.74	0.59	0.82	0.63	0.61	0.60	0.48	0.59	0.78	0.82	0.65	0.75	0.41	1.00	0.76	1.00	0.63	0.52	0.48	0.74	0.75	0.70
7329 (UBE2I)	0.63	0.58	0.62	0.55	0.65	0.56	0.61	0.70	0.47	0.77	0.65	0.62	0.61	1.00	1.00	0.60	0.59	0.67	1.00	0.61	0.59	0.68	0.67	0.72	0.62	0.65	0.52	0.67	0.57	0.42	0.69	0.54	0.47	0.60	0.60	0.62	0.72	0.68	0.42	0.63	0.37	1.00	0.58	0.63	1.00	0.63	0.48	0.58	0.66	0.64
5427 (POLE2)	0.66	0.49	0.71	0.48	0.52	0.41	0.61	0.52	0.31	0.57	0.54	0.66	0.57	1.00	1.00	0.54	0.40	0.62	1.00	0.62	0.51	0.63	0.60	0.60	0.50	0.57	0.41	0.75	0.41	0.29	0.61	0.41	0.30	0.50	0.61	0.66	0.53	0.63	0.27	0.45	0.24	1.00	0.51	0.52	0.63	1.00	0.48	0.49	0.56	0.50
2178 (FANCE)	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	1.00	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.28	0.48	0.48	0.48	0.48	0.48	1.00	0.48	0.48	0.48
5982 (RFC2)	0.51	1.00	0.51	0.44	0.71	0.53	0.41	0.60	0.36	0.58	0.57	0.56	0.84	1.00	1.00	0.47	0.65	0.64	1.00	0.49	0.73	0.67	0.51	0.47	0.56	0.57	0.39	0.66	0.66	0.47	0.67	0.52	0.60	0.51	0.46	0.56	0.60	0.67	0.52	0.55	0.31	1.00	0.65	0.74	0.58	0.49	0.48	1.00	0.71	0.57
4292 (MLH1)	0.69	0.71	0.68	0.53	0.81	0.62	0.48	0.77	0.53	0.68	0.74	0.73	0.77	1.00	1.00	0.54	0.71	0.69	1.00	0.57	0.78	0.72	0.56	0.54	0.67	0.66	0.49	0.66	0.69	0.63	0.77	0.58	0.69	0.60	0.62	0.73	0.74	0.72	0.63	0.74	0.42	1.00	0.64	0.75	0.66	0.56	0.48	0.71	1.00	0.69
2067 (ERCC1)	0.73	0.57	0.69	0.72	0.67	0.77	0.48	0.77	0.71	0.68	0.66	0.54	0.60	1.00	1.00	0.50	0.70	0.75	1.00	0.50	0.60	0.76	0.52	0.49	0.96	0.69	0.71	0.63	0.66	0.50	0.80	0.80	0.65	0.74	0.48	0.54	0.76	0.76	0.48	0.78	0.69	1.00	0.49	0.70	0.64	0.50	0.48	0.57	0.69	1.00

Association with High Altitude

Protein Official symbol	Source Organism	Tissue of Expression	Level of hypoxia	Altitude	Duration of experiment	Level of expression	Fold change	Experiment details	geographical location	ethnicity of the patients	Control group	Control (Fold change)	Reference (PMID)
BLM	Mice	Blood	8% Oxygen	7600 m	24 hours	upregulated	13.1	RT-qPCR	Western US	C57BL/6 mice	3.5	7600m mice(8% oxygen with Fenofibrate injections Vs Baseline normoxia mice (21% oxygen)	24183776
BLM	Mice	Blood	8% Oxygen	7600 m	24 hours	upregulated	13.9	RT-qPCR	Western US	C57BL/6 mice	3.5	7600m mice(8% oxygen with no Fenofibrate injections Vs Baseline normoxia mice (21% oxygen)	24183776

Association with TF

TF	TF Entrez	Gene	Gene Entrez	Type	PMID	Database
E2F4	1874	BLM	641	proximal_filtered	22955619	TRANSFAC
E2F1	1869	BLM	641	proximal_filtered	22955619	TRANSFAC
ESR1	2099	BLM	641	Unknown	14739605	TRUSST

Association with miRNA

miRTarBase ID	miRNA	Species (miRNA)	Protein Official Symbol	Human Entrez ID	Species (Target Gene)	Experiments	Support Type	References (PMID)
MIRT016590	hsa-miR-193b-3p	Homo sapiens	BLM	641	Homo sapiens	Microarray	Functional MTI (Weak)	20304954
MIRT024921	hsa-miR-215-5p	Homo sapiens	BLM	641	Homo sapiens	Microarray	Functional MTI (Weak)	19074876
MIRT026815	hsa-miR-192-5p	Homo sapiens	BLM	641	Homo sapiens	Microarray	Functional MTI (Weak)	19074876

Gene Ontology

ID	GO ID	GO Term	GO Type
641	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	GOTERM_BP_DIRECT
641	GO:0000724	double-strand break repair via homologous recombination	GOTERM_BP_DIRECT
641	GO:0006281	DNA repair	GOTERM_BP_DIRECT
641	GO:0006310	DNA recombination	GOTERM_BP_DIRECT
641	GO:0031297	replication fork processing	GOTERM_BP_DIRECT
641	GO:0072757	cellular response to camptothecin	GOTERM_BP_DIRECT
641	GO:0004386	glycogen	GOTERM_MF_DIRECT
641	GO:0045893	positive regulation of transcription	GOTERM_BP_DIRECT
641	GO:0036310	13-prostaglandin reductase activity	GOTERM_MF_DIRECT
641	GO:0000732	strand displacement	GOTERM_BP_DIRECT
641	GO:0016925	protein sumoylation	GOTERM_BP_DIRECT
641	GO:0071479	cellular response to ionizing radiation	GOTERM_BP_DIRECT
641	GO:0000729	DNA double-strand break processing	GOTERM_BP_DIRECT
641	GO:0000731	DNA synthesis involved in DNA repair	GOTERM_BP_DIRECT
641	GO:0051880	Hsp90 protein binding	GOTERM_MF_DIRECT
641	GO:0072711	cellular response to hydroxyurea	GOTERM_BP_DIRECT
641	GO:0006260	DNA replication	GOTERM_BP_DIRECT
641	GO:0010165	response to X-ray	GOTERM_BP_DIRECT
641	GO:0007095	mitotic G2 DNA damage checkpoint	GOTERM_BP_DIRECT
641	GO:0045910	negative regulation of DNA recombination	GOTERM_BP_DIRECT
641	GO:0009378	electron carrier activity	GOTERM_MF_DIRECT
641	GO:0016887	ATPase activity	GOTERM_MF_DIRECT
641	GO:0005524	ATP binding	GOTERM_MF_DIRECT
641	GO:0016818	hydrolase activity	GOTERM_MF_DIRECT
641	GO:0002039	protease binding	GOTERM_MF_DIRECT
641	GO:0003677	DNA binding	GOTERM_MF_DIRECT
641	GO:0005634	nucleus	GOTERM_CC_DIRECT
641	GO:0005730	nucleolus	GOTERM_CC_DIRECT
641	GO:0016363	nuclear matrix	GOTERM_CC_DIRECT
641	GO:0000733	DNA strand renaturation	GOTERM_BP_DIRECT
641	GO:1901796	regulation of signal transduction by p53 class mediator	GOTERM_BP_DIRECT
641	GO:0008026	protein C-terminus binding	GOTERM_MF_DIRECT
641	telomericregion	None	GOTERM_CC_DIRECT
641	GO:0006974	cellular response to DNA damage stimulus	GOTERM_BP_DIRECT
641	GO:0051782	negative regulation of cell division	GOTERM_BP_DIRECT
641	GO:0003697	double-stranded DNA binding	GOTERM_MF_DIRECT
641	GO:0043140	ubiquitin binding	GOTERM_MF_DIRECT
641	GO:0032508	DNA duplex unwinding	GOTERM_BP_DIRECT
641	GO:0004003	acyl-CoA dehydrogenase activity	GOTERM_MF_DIRECT
641	GO:0048478	replication fork protection	GOTERM_BP_DIRECT
641	GO:0051259	protein oligomerization	GOTERM_BP_DIRECT
641	GO:0005515	protein binding	GOTERM_MF_DIRECT
641	GO:0000405	RNA cap binding	GOTERM_MF_DIRECT
641	GO:0000228	nuclear chromosome	GOTERM_CC_DIRECT
641	GO:0016605	PML body	GOTERM_CC_DIRECT
641	GO:0000781	chromosome	GOTERM_CC_DIRECT
641	GO:0005654	nucleoplasm	GOTERM_CC_DIRECT
641	GO:0000800	lateral element	GOTERM_CC_DIRECT
641	GO:0005737	cytoplasm	GOTERM_CC_DIRECT

Pathways

Human Entrez ID	KEGG ID	KEGG Term
641	hsa03440	Homologous recombination
641	hsa03460	Fanconi anemia pathway

Association with Disease

Protein Official Symbol	Human Entrez ID	Disease Name	Disease Id	Disease Semantic Type	Semantic score	DSI	DPI	Disease Type
BLM	641	leukemia	C0023418	Neoplastic Process	0.42	0.562	0.69	disease
BLM	641	Squamous cell carcinoma	C0007137	Neoplastic Process	0.4	0.562	0.69	disease
BLM	641	Malignant Neoplasms	C0006826	Neoplastic Process	0.3	0.562	0.69	group
BLM	641	Lymphoma	C0024299	Neoplastic Process	0.41	0.562	0.69	group
BLM	641	Bloom Syndrome	C0005859	Disease or Syndrome	1	0.562	0.69	disease
BLM	641	Hematologic Neoplasms	C0376545	Neoplastic Process	0.4	0.562	0.69	group
BLM	641	Intellectual Disability	C3714756	Mental or Behavioral Dysfunction	0.3	0.562	0.69	group
BLM	641	Primary microcephaly	C0431350	Congenital Abnormality	0.3	0.562	0.69	disease
BLM	641	Osteogenesis Imperfecta	C0029434	Congenital Abnormality; Disease or Syndrome	0.3	0.562	0.69	disease

Association with Drug

Protein Official Symbol	Human Entrez ID	drug_claim_primary_name	drug_name	drug_chembl_id	interaction_types
BLM	641	HYDROXYUREA	HYDROXYUREA	CHEMBL467	None
BLM	641	TRICHOSTATIN A	TRICHOSTATIN	CHEMBL99	None