ALTITUDEOMICSDB

Syntaxin-1A

AltitudeomicsDB

Protein Official symbol	STX1A
Aliases	STX1A STX1
Chromosomal Location	7
Length	288
Uniprot ID	Q16623
EC number	None
Protein family Information(Pfam)	PF05739;PF00804;
PDB id	None
InterPro ID	IPR010989;IPR028669;IPR006012;IPR006011;IPR000727;
dbSNP	None

Protein Protein Interaction

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AltitudeomicsDB

Protein 1	Protein 2	Combine Score
VAMP2	SNAP25	0.999
SYT1	STX1A	0.999
STX16	VAMP4	0.999
SNAP25	STX1A	0.999
SYT1	SNAP25	0.999
STXBP1	STX1A	0.999
VAMP2	SNAP23	0.999
VAMP8	STX17	0.999
SNAP23	VAMP3	0.999
VAMP8	SNAP23	0.999
STX6	VAMP4	0.999
SNAP23	STX1A	0.999
GAD1	SLC32A1	0.999
VAMP8	SNAP29	0.999
STX17	SNAP29	0.999
CPLX1	SYT1	0.998
CPLX1	SNAP25	0.998
STXBP1	SNAP25	0.998
STX16	NAPA	0.998
VAMP2	STX1A	0.998
STX16	STX6	0.997
RIMS1	UNC13B	0.997
RIMS1	RAB3A	0.996
NSF	NAPA	0.996
CPLX1	STX1A	0.996
VAMP7	SNAP29	0.996
VAMP7	SNAP23	0.995
VAMP8	STX6	0.995
NAPB	STX16	0.995
STX12	STX6	0.994
GAD2	SLC32A1	0.994
STX6	SNAP23	0.994
STX16	SNAP29	0.994
VAMP2	SYT1	0.994
STX6	VAMP3	0.993
STXBP2	STX1A	0.992
NAPA	STX6	0.992
STX5	STX6	0.991
SNAP25	RAB3A	0.991
NSF	STX5	0.991
VAMP2	SNAP29	0.99
STX12	VAMP8	0.99
NSF	SNAP25	0.99
VAMP7	STX6	0.99
VAMP2	STX6	0.989
VAMP4	STX1A	0.989
VAMP2	CPLX1	0.988
UNC13B	STX1A	0.988
SLC17A7	SLC32A1	0.988
VAMP8	SNAP25	0.988
NAPA	VAMP4	0.988
STX12	SNAP23	0.987
STX5	NAPA	0.987
VAMP7	SNAP25	0.987
STX12	VAMP7	0.987
STX16	VAMP3	0.986
STX12	VAMP3	0.986
SYN1	SNAP25	0.986
VAMP1	SNAP25	0.986
RIMS1	SNAP25	0.984
VAMP8	VAMP7	0.984
VAMP2	NAPA	0.984
VAMP2	VAMP3	0.984
UNC13B	SNAP25	0.984
VAMP7	STX17	0.984
SYN1	SYT1	0.984
STX16	VAMP7	0.984
STX5	STX17	0.983
NSF	STX6	0.983
VAMP7	VAMP3	0.983
UNC13B	SYT1	0.982
STXBP1	VAMP2	0.982
STX1A	SNAP29	0.982
SNAP23	VAMP4	0.981
SYN1	RAB3A	0.981
STX6	SNAP25	0.981
NSF	STX16	0.981
SYN2	SYT1	0.981
SYT1	RAB3A	0.981
SYT2	VAMP2	0.98
NSF	STX17	0.98
VAMP8	STX1A	0.98
STX6	SNAP29	0.98
STX5	VAMP4	0.979
SYN2	SNAP25	0.979
SNAP25	VAMP3	0.979
VAMP7	STX1A	0.979
UNC13B	RAB3A	0.979
STXBP1	APBA1	0.978
STX6	STX1A	0.978
APBA2	STXBP1	0.978
TXLNA	STX1A	0.978
SYT5	SNAP25	0.978
UNC13B	VAMP2	0.978
NSF	VAMP4	0.978
UNC13B	PPFIA3	0.977
NSF	VAMP3	0.977
STX12	SNAP25	0.977
NSF	STX1A	0.976
RIMS1	PPFIA3	0.976
SYT1	SLC32A1	0.976
SYT1	SLC17A7	0.976
UNC13B	PPFIA1	0.976
DNAJC5	SNAP25	0.976
VAMP7	VAMP4	0.976
STX12	VAMP4	0.975
VAMP8	NAPA	0.975
STX16	SNAP23	0.975
NRXN1	SYT1	0.974
NAPA	SNAP25	0.974
VAMP2	RAB3A	0.974
NAPA	STX1A	0.974
RIMS1	PPFIA1	0.974
VAMP2	VAMP7	0.973
SNAP25	SLC32A1	0.973
STX12	SNAP29	0.973
SYN3	SYT1	0.973
NRXN1	APBA1	0.973
SNAP25	SLC17A7	0.972
NAPA	STX17	0.972
STX1A	VAMP3	0.972
VAMP2	SYN1	0.972
NAPB	NSF	0.971
STXBP5	SNAP25	0.971
ENSG00000263620	SNAP25	0.971
STX12	NAPA	0.971
SYN3	SNAP25	0.971
SYN2	RAB3A	0.971
NAPA	VAMP7	0.97
NAPB	STX5	0.97
NAPB	STX6	0.97
SNAP29	VAMP3	0.97
STX12	VAMP2	0.97
CPLX1	RAB3A	0.97
SYT2	SNAP25	0.969
RIMS1	STX1A	0.969
STX1A	RAB3A	0.969
STX16	SNAP25	0.969
SYT2	CPLX1	0.969
STX16	VAMP8	0.968
STX16	VAMP2	0.968
SNAP23	SNAP29	0.968
NAPA	VAMP3	0.968
SYN2	CPLX1	0.968
STX17	STX6	0.967
STXBP5	STX1A	0.967
GAD2	SNAP25	0.967
VAMP2	SLC17A7	0.967
DNAJC5	RAB3A	0.967
SYT5	VAMP2	0.967
DNAJC5	SYT1	0.967
APBA2	NRXN1	0.966
VAMP1	STX1A	0.966
STX5	SNAP29	0.966
SYT5	STX1A	0.966
SYT1	VAMP4	0.965
CACNA1D	STX1A	0.965
STX12	STX5	0.964
SYN1	STX1A	0.962
STX17	VAMP3	0.962
RIMS1	SYT1	0.962
CPLX1	SYN1	0.962
NRXN1	SYT2	0.962
UNC13B	CPLX1	0.962
DNAJC5	VAMP2	0.961
APBA1	STX1A	0.961
RIMS1	SYN1	0.961
SYN3	RAB3A	0.96
SNAP25	VAMP4	0.96
STX17	SNAP23	0.96
SYT2	VAMP4	0.959
SYN2	VAMP2	0.959
GAD1	SNAP25	0.959
ENSG00000263620	STX1A	0.958
STX17	SNAP25	0.958
PPFIA3	APBA1	0.957
SYT1	VAMP3	0.957
GAD2	SYT1	0.957
STX5	SNAP23	0.957
RAB3A	SLC17A7	0.957
SYT2	VAMP8	0.956
GAD2	GAD1	0.956
INS	VAMP2	0.956
NAPB	SNAP25	0.956
NAPB	VAMP4	0.955
SYT2	VAMP3	0.955
NAPB	VAMP3	0.955
APBA1	SNAP25	0.955
DNAJC5	STX1A	0.955
STX16	STX17	0.954
SYT2	VAMP7	0.954
SYN2	STX1A	0.954
VAMP2	SLC32A1	0.954
APBA1	PPFIA1	0.954
RIMS1	SLC17A7	0.954
SLC18A2	SLC6A3	0.954
STX16	STX1A	0.954
STX5	SNAP25	0.954
VAMP8	SYT1	0.953
SLC6A3	STX1A	0.952
PPFIA3	RAB3A	0.952
SYN2	SYN1	0.952
STX5	VAMP7	0.952
CPLX1	SLC17A7	0.952
NRXN3	APBA1	0.951
NRXN2	SYT1	0.951
VAMP7	SYT1	0.951
SYN3	VAMP2	0.951
STX12	STX17	0.951
NRXN3	SYT1	0.951
RIMS1	VAMP2	0.95
NRXN2	APBA1	0.95
INS	SNAP25	0.95
RAB3A	SLC32A1	0.95
NRXN1	STXBP1	0.949
GAD1	SYT1	0.949
SYN2	RIMS1	0.949
STX5	STX1A	0.948
CPLX1	SNAP23	0.948
VAMP2	STX17	0.948
GAD2	VAMP2	0.947
DNAJC5	SNAP23	0.947
PPFIA3	SYN1	0.947
RIMS1	APBA1	0.947
CPLX1	SLC32A1	0.947
STXBP1	SYT5	0.946
RIMS1	SLC32A1	0.946
APBA2	STX1A	0.946
SYN3	STX1A	0.946
GAD1	RAB3A	0.945
INS	STX1A	0.945
VAMP1	VAMP3	0.945
NSF	INS	0.945
RIMS1	CPLX1	0.944
NAPB	STX17	0.944
UNC13B	SYN1	0.944
PPFIA3	SNAP25	0.944
VAMP1	SNAP23	0.943
STX1A	SLC17A7	0.943
UNC13B	SLC17A7	0.943
PPFIA3	SYT1	0.943
SLC18A2	SNAP25	0.943
GAD2	STX1A	0.943
CACNA1C	STX1A	0.942
CPLX1	SNAP29	0.942
SLC18A2	SLC32A1	0.942
CACNA1C	SNAP25	0.941
PPFIA3	CPLX1	0.941
RIMS1	SYN3	0.941
VAMP2	SLC18A2	0.94
VAMP2	VAMP8	0.94
STXBP1	NRXN2	0.94
VAMP8	VAMP3	0.939
SNAP25	SNAP29	0.939
STX1A	SLC32A1	0.939
STX12	STX1A	0.939
PPFIA1	RAB3A	0.939
NRXN3	SYT2	0.938
SLC18A2	SYT1	0.938
SYN2	PPFIA3	0.938
SYT1	PPFIA1	0.937
INS	CACNA1C	0.937
SLC18A2	SYN1	0.937
NRXN3	STXBP1	0.936
SYN1	PPFIA1	0.936
STX17	STX1A	0.936
PPFIA3	STX1A	0.936
SYN3	CPLX1	0.936
PPFIA3	VAMP2	0.936
SYN2	UNC13B	0.935
CACNA1D	SNAP25	0.935
SNAP25	PPFIA1	0.935
GAD2	CPLX1	0.935
PPFIA3	SLC17A7	0.935
UNC13B	SYN3	0.935
SYT2	NRXN2	0.934
NRXN1	STX1A	0.933
GAD2	RAB3A	0.933
SYN3	SYN1	0.932
INS	CACNA1D	0.932
VAMP2	PPFIA1	0.932
INS	STXBP1	0.932
SYT2	STX1A	0.932
SLC18A2	STX1A	0.931
SYN2	SYN3	0.931
STX12	STX16	0.93
SYN2	PPFIA1	0.93
SYN3	SLC18A2	0.929
DNAJC5	VAMP8	0.928
NAPB	STX1A	0.928
DNAJC5	CPLX1	0.928
SYT2	SYT1	0.928
APBA2	NRXN2	0.928
NRXN2	STX1A	0.927
APBA1	SYT1	0.927
SYT5	CACNA1D	0.927
APBA1	RAB3A	0.927
GAD1	STX1A	0.926
GAD1	CPLX1	0.926
ST8SIA2	STX1A	0.926
STX5	VAMP8	0.926
PPFIA1	STX1A	0.926
NRXN1	NRXN2	0.926
NRXN3	STX1A	0.925
SYN3	PPFIA3	0.925
APBA2	NRXN3	0.925
PPFIA1	SLC17A7	0.925
NAPB	SNAP29	0.925
NAPB	SNAP23	0.925
STXBP1	CACNA1C	0.924
VAMP2	CACNA1C	0.923
SYN2	SLC18A2	0.923
NAPA	SNAP29	0.923
SLC18A2	RAB3A	0.923
UNC13B	APBA1	0.923
PPFIA3	PPFIA1	0.923
GAD1	VAMP2	0.923
NSF	STXBP1	0.922
SYN3	PPFIA1	0.922
RIMS1	GAD2	0.922
VAMP2	CACNA1D	0.921
INS	SYT5	0.921
GAD2	DNAJC5	0.92
STX5	VAMP3	0.92
STXBP1	CACNA1D	0.92
RIMS1	DNAJC5	0.919
CPLX1	PPFIA1	0.918
NRXN3	NRXN1	0.918
DNAJC5	SLC32A1	0.917
SLC18A2	APBA1	0.916
UNC13B	SLC18A2	0.916
SYN2	APBA1	0.916
VAMP2	STX5	0.916
RIMS1	GAD1	0.915
DNAJC5	SNAP29	0.915
CPLX1	APBA1	0.915
CPLX1	SLC18A2	0.915
SYN1	APBA1	0.915
SLC18A2	SLC17A7	0.914
NRXN3	NRXN2	0.914
VAMP2	APBA1	0.913
VAMP8	VAMP4	0.911
NSF	SNAP23	0.91
INS	STX5	0.91
VAMP4	VAMP3	0.909
SYT5	CACNA1C	0.909
INS	NAPA	0.909
VAMP2	VAMP4	0.909
DNAJC5	GAD1	0.908
RIMS1	SLC18A2	0.906
CACNA1D	CACNA1C	0.905
SNAP25	SNAP23	0.904
PPFIA3	SLC18A2	0.903
SYN3	APBA1	0.903
SLC18A2	PPFIA1	0.901
NAPB	INS	0.901
STXBP2	TXLNA	0.901
TXLNA	VAMP2	0.901
TXLNA	SNAP25	0.9
NAPB	NAPA	0.9

Gene Ontology Semantic Similarity

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#	6844 (VAMP2)	6857 (SYT1)	8675 (STX16)	6616 (SNAP25)	6812 (STXBP1)	8673 (VAMP8)	8773 (SNAP23)	10228 (STX6)	2571 (GAD1)	55014 (STX17)	10815 (CPLX1)	22999 (RIMS1)	4905 (NSF)	6845 (VAMP7)	63908 (NAPB)	23673 (STX12)	2572 (GAD2)	6813 (STXBP2)	8775 (NAPA)	6811 (STX5)	8674 (VAMP4)	10497 (UNC13B)	57030 (SLC17A7)	6853 (SYN1)	6843 (VAMP1)	6804 (STX1A)	6854 (SYN2)	127833 (SYT2)	321 (APBA2)	200081 (TXLNA)	6861 (SYT5)	9378 (NRXN1)	8224 (SYN3)	134957 (STXBP5)	9342 (SNAP29)	776 (CACNA1D)	320 (APBA1)	8541 (PPFIA3)	5864 (RAB3A)	3630 (INS)	6571 (SLC18A2)	6531 (SLC6A3)	9369 (NRXN3)	9379 (NRXN2)	775 (CACNA1C)	8500 (PPFIA1)	8128 (ST8SIA2)	9341 (VAMP3)	140679 (SLC32A1)
6844 (VAMP2)	1.00	0.86	0.88	0.90	0.86	0.71	0.85	0.88	0.71	0.82	0.84	0.68	0.75	0.84	0.85	0.84	0.71	0.81	0.85	0.82	1.00	0.83	0.18	0.68	1.00	0.77	0.27	0.84	0.73	0.75	0.80	0.66	0.27	0.68	0.85	0.38	0.73	1.00	0.70	0.74	0.11	0.62	0.59	0.56	0.60	1.00	0.28	1.00	0.08
6857 (SYT1)	0.86	1.00	0.74	0.74	0.74	0.58	0.71	0.74	0.58	0.69	0.69	0.57	0.66	0.70	0.71	0.70	0.58	0.66	0.73	0.70	1.00	0.70	0.16	0.58	1.00	0.66	0.30	0.92	0.60	0.62	0.93	0.65	0.30	0.57	0.71	0.33	0.60	1.00	0.58	0.64	0.10	0.54	0.50	0.48	0.50	1.00	0.33	1.00	0.07
8675 (STX16)	0.88	0.74	1.00	0.95	0.89	0.74	0.98	1.00	0.75	0.93	0.94	0.69	0.74	0.98	0.93	0.98	0.75	0.89	0.91	0.93	1.00	0.80	0.17	0.68	1.00	0.85	0.15	0.74	0.79	0.80	0.72	0.66	0.15	0.70	0.98	0.35	0.79	1.00	0.72	0.78	0.12	0.61	0.63	0.57	0.55	1.00	0.25	1.00	0.09
6616 (SNAP25)	0.90	0.74	0.95	1.00	0.88	0.72	0.96	0.95	0.73	0.87	0.86	0.68	0.75	0.90	0.91	0.90	0.73	0.87	0.87	0.87	1.00	0.83	0.17	0.67	1.00	0.81	0.15	0.72	0.76	0.78	0.69	0.66	0.15	0.72	0.96	0.36	0.76	1.00	0.71	0.76	0.11	0.61	0.61	0.56	0.55	1.00	0.24	1.00	0.08
6812 (STXBP1)	0.86	0.74	0.89	0.88	1.00	0.68	0.86	0.89	0.68	0.82	0.84	0.76	0.74	0.84	0.86	0.84	0.68	0.81	0.86	0.83	1.00	0.79	0.17	0.65	1.00	0.76	0.24	0.72	0.71	0.73	0.70	0.64	0.24	0.70	0.86	0.35	0.71	1.00	0.67	0.76	0.11	0.58	0.58	0.54	0.54	1.00	0.24	1.00	0.08
8673 (VAMP8)	0.71	0.58	0.74	0.72	0.68	1.00	0.73	0.74	0.58	0.73	0.74	0.59	0.61	0.76	0.73	0.76	0.58	0.69	0.72	0.75	1.00	0.67	0.16	0.55	1.00	0.90	0.15	0.57	0.64	0.69	0.52	0.63	0.15	0.48	0.73	0.27	0.64	1.00	0.58	0.70	0.11	0.44	0.53	0.56	0.43	1.00	0.21	1.00	0.08
8773 (SNAP23)	0.85	0.71	0.98	0.96	0.86	0.73	1.00	0.98	0.73	0.90	0.90	0.67	0.71	0.95	0.94	0.95	0.73	0.91	0.88	0.90	1.00	0.79	0.17	0.66	1.00	0.82	0.15	0.70	0.78	0.80	0.67	0.65	0.15	0.68	1.00	0.33	0.78	1.00	0.71	0.77	0.12	0.58	0.62	0.56	0.52	1.00	0.25	1.00	0.09
10228 (STX6)	0.88	0.74	1.00	0.95	0.89	0.74	0.98	1.00	0.75	0.93	0.94	0.69	0.74	0.98	0.93	0.98	0.75	0.89	0.91	0.93	1.00	0.80	0.17	0.68	1.00	0.85	0.15	0.74	0.79	0.80	0.72	0.66	0.15	0.70	0.98	0.35	0.79	1.00	0.72	0.78	0.12	0.61	0.63	0.57	0.55	1.00	0.25	1.00	0.09
2571 (GAD1)	0.71	0.58	0.75	0.73	0.68	0.58	0.73	0.75	1.00	0.73	0.74	0.57	0.61	0.76	0.73	0.76	1.00	0.69	0.72	0.76	1.00	0.67	0.16	0.55	1.00	0.66	0.15	0.57	0.64	0.69	0.52	0.57	0.15	0.45	0.73	0.27	0.64	1.00	0.58	0.70	0.11	0.45	0.53	0.47	0.43	1.00	0.25	1.00	0.08
55014 (STX17)	0.82	0.69	0.93	0.87	0.82	0.73	0.90	0.93	0.73	1.00	0.90	0.68	0.71	0.94	0.85	0.94	0.73	0.83	0.85	0.90	1.00	0.76	0.17	0.67	1.00	0.83	0.15	0.69	0.77	0.79	0.65	0.65	0.15	0.59	0.90	0.35	0.77	1.00	0.71	0.77	0.11	0.59	0.62	0.56	0.54	1.00	0.25	1.00	0.08
10815 (CPLX1)	0.84	0.69	0.94	0.86	0.84	0.74	0.90	0.94	0.74	0.90	1.00	0.67	0.71	0.96	0.90	0.96	0.74	0.89	0.89	0.90	1.00	0.77	0.17	0.65	1.00	0.81	0.15	0.69	0.81	0.82	0.68	0.64	0.15	0.62	0.90	0.32	0.81	1.00	0.71	0.78	0.12	0.56	0.64	0.56	0.50	1.00	0.26	1.00	0.09
22999 (RIMS1)	0.68	0.57	0.69	0.68	0.76	0.59	0.67	0.69	0.57	0.68	0.67	1.00	0.67	0.69	0.67	0.69	0.57	0.64	0.68	0.70	1.00	0.73	0.16	0.57	1.00	0.65	0.24	0.57	0.61	0.64	0.51	0.59	0.24	0.71	0.67	0.30	0.61	1.00	0.57	0.66	0.11	0.49	0.50	0.50	0.46	1.00	0.21	1.00	0.08
4905 (NSF)	0.75	0.66	0.74	0.75	0.74	0.61	0.71	0.74	0.61	0.71	0.71	0.67	1.00	0.72	0.71	0.72	0.61	0.67	0.79	0.73	1.00	0.77	0.17	0.65	1.00	0.71	0.15	0.64	0.63	0.65	0.58	0.59	0.15	0.64	0.71	0.33	0.63	1.00	0.71	0.66	0.10	0.54	0.52	0.50	0.51	1.00	0.22	1.00	0.07
6845 (VAMP7)	0.84	0.70	0.98	0.90	0.84	0.76	0.95	0.98	0.76	0.94	0.96	0.69	0.72	1.00	0.89	1.00	0.76	0.87	0.88	0.94	1.00	0.77	0.17	0.67	1.00	0.85	0.15	0.70	0.81	0.82	0.67	0.66	0.15	0.61	0.95	0.34	0.81	1.00	0.73	0.79	0.12	0.59	0.64	0.57	0.53	1.00	0.26	1.00	0.09
63908 (NAPB)	0.85	0.71	0.93	0.91	0.86	0.73	0.94	0.93	0.73	0.85	0.90	0.67	0.71	0.89	1.00	0.89	0.73	0.91	0.93	0.85	1.00	0.79	0.17	0.66	1.00	0.77	0.15	0.70	0.78	0.80	0.67	0.65	0.15	0.68	0.94	0.33	0.78	1.00	0.71	0.77	0.12	0.58	0.62	0.56	0.52	1.00	0.25	1.00	0.09
23673 (STX12)	0.84	0.70	0.98	0.90	0.84	0.76	0.95	0.98	0.76	0.94	0.96	0.69	0.72	1.00	0.89	1.00	0.76	0.87	0.88	0.94	1.00	0.77	0.17	0.67	1.00	0.85	0.15	0.70	0.81	0.82	0.67	0.66	0.15	0.61	0.95	0.34	0.81	1.00	0.73	0.79	0.12	0.59	0.64	0.57	0.53	1.00	0.26	1.00	0.09
2572 (GAD2)	0.71	0.58	0.75	0.73	0.68	0.58	0.73	0.75	1.00	0.73	0.74	0.57	0.61	0.76	0.73	0.76	1.00	0.69	0.72	0.76	1.00	0.67	0.16	0.55	1.00	0.66	0.15	0.57	0.64	0.69	0.52	0.57	0.15	0.45	0.73	0.27	0.64	1.00	0.58	0.70	0.11	0.45	0.53	0.47	0.43	1.00	0.25	1.00	0.08
6813 (STXBP2)	0.81	0.66	0.89	0.87	0.81	0.69	0.91	0.89	0.69	0.83	0.89	0.64	0.67	0.87	0.91	0.87	0.69	1.00	0.85	0.84	1.00	0.76	0.16	0.62	1.00	0.74	0.15	0.66	0.75	0.78	0.64	0.62	0.15	0.63	0.91	0.30	0.75	1.00	0.67	0.76	0.11	0.52	0.60	0.53	0.48	1.00	0.24	1.00	0.08
8775 (NAPA)	0.85	0.73	0.91	0.87	0.86	0.72	0.88	0.91	0.72	0.85	0.89	0.68	0.79	0.88	0.93	0.88	0.72	0.85	1.00	0.86	1.00	0.78	0.18	0.67	1.00	0.79	0.15	0.73	0.76	0.78	0.70	0.66	0.15	0.67	0.88	0.36	0.76	1.00	0.71	0.76	0.12	0.60	0.61	0.56	0.55	1.00	0.26	1.00	0.09
6811 (STX5)	0.82	0.70	0.93	0.87	0.83	0.75	0.90	0.93	0.76	0.90	0.90	0.70	0.73	0.94	0.85	0.94	0.76	0.84	0.86	1.00	1.00	0.77	0.18	0.69	1.00	0.83	0.15	0.71	0.79	0.80	0.66	0.69	0.15	0.59	0.90	0.37	0.79	1.00	0.73	0.78	0.12	0.63	0.67	0.62	0.57	1.00	0.25	1.00	0.09
8674 (VAMP4)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.26	1.00	1.00	1.00	0.15	1.00	1.00	1.00	0.82	1.00	0.15	0.69	1.00	0.69	1.00	1.00	1.00	1.00	0.15	1.00	0.82	0.82	1.00	1.00	0.31	1.00	0.11
10497 (UNC13B)	0.83	0.70	0.80	0.83	0.79	0.67	0.79	0.80	0.67	0.76	0.77	0.73	0.77	0.77	0.79	0.77	0.67	0.76	0.78	0.77	1.00	1.00	0.17	0.63	1.00	0.71	0.15	0.67	0.70	0.72	0.62	0.63	0.15	0.71	0.79	0.34	0.70	1.00	0.66	0.72	0.11	0.57	0.57	0.53	0.56	1.00	0.24	1.00	0.08
57030 (SLC17A7)	0.18	0.16	0.17	0.17	0.17	0.16	0.17	0.17	0.16	0.17	0.17	0.16	0.17	0.17	0.17	0.17	0.16	0.16	0.18	0.18	0.26	0.17	1.00	0.35	0.26	0.17	0.07	0.16	0.16	0.16	0.14	0.18	0.07	0.12	0.17	0.26	0.16	0.26	0.15	0.17	0.45	0.39	0.15	0.15	0.25	0.26	0.10	0.26	0.55
6853 (SYN1)	0.68	0.58	0.68	0.67	0.65	0.55	0.66	0.68	0.55	0.67	0.65	0.57	0.65	0.67	0.66	0.67	0.55	0.62	0.67	0.69	1.00	0.63	0.35	1.00	1.00	0.67	1.00	0.57	0.58	0.63	0.52	0.56	1.00	0.42	0.66	0.33	0.58	1.00	0.55	0.65	0.22	0.52	0.49	0.46	0.48	1.00	0.27	1.00	0.16
6843 (VAMP1)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.26	1.00	1.00	1.00	0.15	1.00	1.00	1.00	0.82	1.00	0.15	0.69	1.00	0.69	1.00	1.00	1.00	1.00	0.15	1.00	0.82	0.82	1.00	1.00	0.31	1.00	0.11
6804 (STX1A)	0.77	0.66	0.85	0.81	0.76	0.90	0.82	0.85	0.66	0.83	0.81	0.65	0.71	0.85	0.77	0.85	0.66	0.74	0.79	0.83	1.00	0.71	0.17	0.67	1.00	1.00	0.15	0.66	0.70	0.72	0.61	0.67	0.15	0.56	0.82	0.33	0.70	1.00	0.65	0.72	0.11	0.55	0.57	0.59	0.51	1.00	0.23	1.00	0.08
6854 (SYN2)	0.27	0.30	0.15	0.15	0.24	0.15	0.15	0.15	0.15	0.15	0.15	0.24	0.15	0.15	0.15	0.15	0.15	0.15	0.15	0.15	0.15	0.15	0.07	1.00	0.15	0.15	1.00	0.31	0.15	0.15	0.30	0.16	1.00	0.11	0.15	0.11	0.15	0.15	0.15	0.15	0.04	0.22	0.12	0.12	0.15	0.15	0.35	0.15	0.03
127833 (SYT2)	0.84	0.92	0.74	0.72	0.72	0.57	0.70	0.74	0.57	0.69	0.69	0.57	0.64	0.70	0.70	0.70	0.57	0.66	0.73	0.71	1.00	0.67	0.16	0.57	1.00	0.66	0.31	1.00	0.60	0.62	0.95	0.66	0.31	0.54	0.70	0.32	0.60	1.00	0.57	0.64	0.10	0.53	0.49	0.47	0.48	1.00	0.38	1.00	0.08
321 (APBA2)	0.73	0.60	0.79	0.76	0.71	0.64	0.78	0.79	0.64	0.77	0.81	0.61	0.63	0.81	0.78	0.81	0.64	0.75	0.76	0.79	1.00	0.70	0.16	0.58	1.00	0.70	0.15	0.60	1.00	0.74	0.55	0.60	0.15	0.48	0.78	0.29	1.00	1.00	0.63	0.73	0.12	0.49	0.57	0.50	0.45	1.00	0.25	1.00	0.08
200081 (TXLNA)	0.75	0.62	0.80	0.78	0.73	0.69	0.80	0.80	0.69	0.79	0.82	0.64	0.65	0.82	0.80	0.82	0.69	0.78	0.78	0.80	1.00	0.72	0.16	0.63	1.00	0.72	0.15	0.62	0.74	1.00	0.57	0.63	0.15	0.50	0.80	0.32	0.74	1.00	0.67	0.76	0.11	0.55	0.64	0.57	0.50	1.00	0.24	1.00	0.08
6861 (SYT5)	0.80	0.93	0.72	0.69	0.70	0.52	0.67	0.72	0.52	0.65	0.68	0.51	0.58	0.67	0.67	0.67	0.52	0.64	0.70	0.66	0.82	0.62	0.14	0.52	0.82	0.61	0.30	0.95	0.55	0.57	1.00	0.60	0.30	0.54	0.67	0.27	0.55	0.82	0.52	0.57	0.10	0.48	0.45	0.42	0.42	0.82	0.36	0.82	0.07
9378 (NRXN1)	0.66	0.65	0.66	0.66	0.64	0.63	0.65	0.66	0.57	0.65	0.64	0.59	0.59	0.66	0.65	0.66	0.57	0.62	0.66	0.69	1.00	0.63	0.18	0.56	1.00	0.67	0.16	0.66	0.60	0.63	0.60	1.00	0.16	0.44	0.65	0.31	0.60	1.00	0.57	0.65	0.11	0.52	0.80	0.85	0.48	1.00	0.22	1.00	0.08
8224 (SYN3)	0.27	0.30	0.15	0.15	0.24	0.15	0.15	0.15	0.15	0.15	0.15	0.24	0.15	0.15	0.15	0.15	0.15	0.15	0.15	0.15	0.15	0.15	0.07	1.00	0.15	0.15	1.00	0.31	0.15	0.15	0.30	0.16	1.00	0.11	0.15	0.11	0.15	0.15	0.15	0.15	0.04	0.22	0.12	0.12	0.15	0.15	0.35	0.15	0.03
134957 (STXBP5)	0.68	0.57	0.70	0.72	0.70	0.48	0.68	0.70	0.45	0.59	0.62	0.71	0.64	0.61	0.68	0.61	0.45	0.63	0.67	0.59	0.69	0.71	0.12	0.42	0.69	0.56	0.11	0.54	0.48	0.50	0.54	0.44	0.11	1.00	0.68	0.22	0.48	0.69	0.44	0.50	0.08	0.37	0.39	0.39	0.34	0.69	0.16	0.69	0.06
9342 (SNAP29)	0.85	0.71	0.98	0.96	0.86	0.73	1.00	0.98	0.73	0.90	0.90	0.67	0.71	0.95	0.94	0.95	0.73	0.91	0.88	0.90	1.00	0.79	0.17	0.66	1.00	0.82	0.15	0.70	0.78	0.80	0.67	0.65	0.15	0.68	1.00	0.33	0.78	1.00	0.71	0.77	0.12	0.58	0.62	0.56	0.52	1.00	0.25	1.00	0.09
776 (CACNA1D)	0.38	0.33	0.35	0.36	0.35	0.27	0.33	0.35	0.27	0.35	0.32	0.30	0.33	0.34	0.33	0.34	0.27	0.30	0.36	0.37	0.69	0.34	0.26	0.33	0.69	0.33	0.11	0.32	0.29	0.32	0.27	0.31	0.11	0.22	0.33	1.00	0.29	0.69	0.30	0.36	0.27	0.40	0.25	0.24	0.90	0.69	0.11	0.69	0.22
320 (APBA1)	0.73	0.60	0.79	0.76	0.71	0.64	0.78	0.79	0.64	0.77	0.81	0.61	0.63	0.81	0.78	0.81	0.64	0.75	0.76	0.79	1.00	0.70	0.16	0.58	1.00	0.70	0.15	0.60	1.00	0.74	0.55	0.60	0.15	0.48	0.78	0.29	1.00	1.00	0.63	0.73	0.12	0.49	0.57	0.50	0.45	1.00	0.25	1.00	0.08
8541 (PPFIA3)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.26	1.00	1.00	1.00	0.15	1.00	1.00	1.00	0.82	1.00	0.15	0.69	1.00	0.69	1.00	1.00	1.00	1.00	0.15	1.00	0.82	0.82	1.00	1.00	0.31	1.00	0.11
5864 (RAB3A)	0.70	0.58	0.72	0.71	0.67	0.58	0.71	0.72	0.58	0.71	0.71	0.57	0.71	0.73	0.71	0.73	0.58	0.67	0.71	0.73	1.00	0.66	0.15	0.55	1.00	0.65	0.15	0.57	0.63	0.67	0.52	0.57	0.15	0.44	0.71	0.30	0.63	1.00	1.00	0.69	0.10	0.46	0.52	0.47	0.44	1.00	0.22	1.00	0.08
3630 (INS)	0.74	0.64	0.78	0.76	0.76	0.70	0.77	0.78	0.70	0.77	0.78	0.66	0.66	0.79	0.77	0.79	0.70	0.76	0.76	0.78	1.00	0.72	0.17	0.65	1.00	0.72	0.15	0.64	0.73	0.76	0.57	0.65	0.15	0.50	0.77	0.36	0.73	1.00	0.69	1.00	0.11	0.60	0.64	0.59	0.55	1.00	0.23	1.00	0.08
6571 (SLC18A2)	0.11	0.10	0.12	0.11	0.11	0.11	0.12	0.12	0.11	0.11	0.12	0.11	0.10	0.12	0.12	0.12	0.11	0.11	0.12	0.12	0.15	0.11	0.45	0.22	0.15	0.11	0.04	0.10	0.12	0.11	0.10	0.11	0.04	0.08	0.12	0.27	0.12	0.15	0.10	0.11	1.00	0.66	0.11	0.10	0.23	0.15	0.08	0.15	0.50
6531 (SLC6A3)	0.62	0.54	0.61	0.61	0.58	0.44	0.58	0.61	0.45	0.59	0.56	0.49	0.54	0.59	0.58	0.59	0.45	0.52	0.60	0.63	1.00	0.57	0.39	0.52	1.00	0.55	0.22	0.53	0.49	0.55	0.48	0.52	0.22	0.37	0.58	0.40	0.49	1.00	0.46	0.60	0.66	1.00	0.42	0.39	0.50	1.00	0.20	1.00	0.36
9369 (NRXN3)	0.59	0.50	0.63	0.61	0.58	0.53	0.62	0.63	0.53	0.62	0.64	0.50	0.52	0.64	0.62	0.64	0.53	0.60	0.61	0.67	0.82	0.57	0.15	0.49	0.82	0.57	0.12	0.49	0.57	0.64	0.45	0.80	0.12	0.39	0.62	0.25	0.57	0.82	0.52	0.64	0.11	0.42	1.00	0.82	0.39	0.82	0.20	0.82	0.08
9379 (NRXN2)	0.56	0.48	0.57	0.56	0.54	0.56	0.56	0.57	0.47	0.56	0.56	0.50	0.50	0.57	0.56	0.57	0.47	0.53	0.56	0.62	0.82	0.53	0.15	0.46	0.82	0.59	0.12	0.47	0.50	0.57	0.42	0.85	0.12	0.39	0.56	0.24	0.50	0.82	0.47	0.59	0.10	0.39	0.82	1.00	0.37	0.82	0.18	0.82	0.07
775 (CACNA1C)	0.60	0.50	0.55	0.55	0.54	0.43	0.52	0.55	0.43	0.54	0.50	0.46	0.51	0.53	0.52	0.53	0.43	0.48	0.55	0.57	1.00	0.56	0.25	0.48	1.00	0.51	0.15	0.48	0.45	0.50	0.42	0.48	0.15	0.34	0.52	0.90	0.45	1.00	0.44	0.55	0.23	0.50	0.39	0.37	1.00	1.00	0.15	1.00	0.19
8500 (PPFIA1)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.26	1.00	1.00	1.00	0.15	1.00	1.00	1.00	0.82	1.00	0.15	0.69	1.00	0.69	1.00	1.00	1.00	1.00	0.15	1.00	0.82	0.82	1.00	1.00	0.31	1.00	0.11
8128 (ST8SIA2)	0.28	0.33	0.25	0.24	0.24	0.21	0.25	0.25	0.25	0.25	0.26	0.21	0.22	0.26	0.25	0.26	0.25	0.24	0.26	0.25	0.31	0.24	0.10	0.27	0.31	0.23	0.35	0.38	0.25	0.24	0.36	0.22	0.35	0.16	0.25	0.11	0.25	0.31	0.22	0.23	0.08	0.20	0.20	0.18	0.15	0.31	1.00	0.31	0.06
9341 (VAMP3)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.26	1.00	1.00	1.00	0.15	1.00	1.00	1.00	0.82	1.00	0.15	0.69	1.00	0.69	1.00	1.00	1.00	1.00	0.15	1.00	0.82	0.82	1.00	1.00	0.31	1.00	0.11
140679 (SLC32A1)	0.08	0.07	0.09	0.08	0.08	0.08	0.09	0.09	0.08	0.08	0.09	0.08	0.07	0.09	0.09	0.09	0.08	0.08	0.09	0.09	0.11	0.08	0.55	0.16	0.11	0.08	0.03	0.08	0.08	0.08	0.07	0.08	0.03	0.06	0.09	0.22	0.08	0.11	0.08	0.08	0.50	0.36	0.08	0.07	0.19	0.11	0.06	0.11	1.00

Association with High Altitude

Protein Official symbol	Source Organism	Tissue of Expression	Level of hypoxia	Altitude	Duration of experiment	Level of expression	Fold change	Experiment details	geographical location	ethnicity of the patients	Control group	Control (Fold change)	Reference (PMID)
STX1A	Bird	Flight Muscle	-	4000 m	Native	downregulated	-6.78	Sequencing	Central Asia	L. dichrous (Bird)	1	L. dichrous vs. Po. Palustris	31127049
STX1A	Human	Blood	-	3650 m	48 hours	upregulated	1.609	Microarray	Himalayas	Indians	1	HAPE Pateints Vs Normal	http://medind.nic.in/iab/t12/i1/iabt12i1p1.pdf
STX1A	Rat	Left brain cortices	300hPa	9144 m	1 hour	downregulated	0.96±0.0	TMT labeled LTQ orbitrap	Southwestern europe	Male wistar rats	1	Adult male Wistar rats weighing 350 g	28697276

Association with TF

TF	TF Entrez	Gene	Gene Entrez	Type	PMID	Database

Association with miRNA

miRTarBase ID	miRNA	Species (miRNA)	Protein Official Symbol	Human Entrez ID	Species (Target Gene)	Experiments	Support Type	References (PMID)
MIRT006305	hsa-miR-34a-5p	Homo sapiens	STX1A	6804	Homo sapiens	Luciferase reporter assay//Western blot	Functional MTI	22160687
MIRT018783	hsa-miR-335-5p	Homo sapiens	STX1A	6804	Homo sapiens	Microarray	Functional MTI (Weak)	18185580
MIRT030051	hsa-miR-26b-5p	Homo sapiens	STX1A	6804	Homo sapiens	Microarray	Functional MTI (Weak)	19088304
MIRT736325	hsa-miR-1237-5p	Homo sapiens	STX1A	6804	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT736474	hsa-miR-1249-5p	Homo sapiens	STX1A	6804	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT737002	hsa-miR-128-2-5p	Homo sapiens	STX1A	6804	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT736983	hsa-miR-128-1-5p	Homo sapiens	STX1A	6804	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT737375	hsa-miR-1321	Homo sapiens	STX1A	6804	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT737797	hsa-miR-149-3p	Homo sapiens	STX1A	6804	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT740425	hsa-miR-3154	Homo sapiens	STX1A	6804	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT742962	hsa-miR-3919	Homo sapiens	STX1A	6804	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT744213	hsa-miR-4419a	Homo sapiens	STX1A	6804	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT745248	hsa-miR-4488	Homo sapiens	STX1A	6804	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT745653	hsa-miR-4510	Homo sapiens	STX1A	6804	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT746350	hsa-miR-4641	Homo sapiens	STX1A	6804	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT747251	hsa-miR-4697-5p	Homo sapiens	STX1A	6804	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT747893	hsa-miR-4728-5p	Homo sapiens	STX1A	6804	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT748092	hsa-miR-4739	Homo sapiens	STX1A	6804	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT748464	hsa-miR-4756-5p	Homo sapiens	STX1A	6804	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT752127	hsa-miR-6127	Homo sapiens	STX1A	6804	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT752200	hsa-miR-6129	Homo sapiens	STX1A	6804	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT752392	hsa-miR-6133	Homo sapiens	STX1A	6804	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT752288	hsa-miR-6130	Homo sapiens	STX1A	6804	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT755297	hsa-miR-6770-5p	Homo sapiens	STX1A	6804	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT755689	hsa-miR-6781-5p	Homo sapiens	STX1A	6804	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT755888	hsa-miR-6785-5p	Homo sapiens	STX1A	6804	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT756234	hsa-miR-6797-5p	Homo sapiens	STX1A	6804	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT756455	hsa-miR-6804-5p	Homo sapiens	STX1A	6804	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT757449	hsa-miR-6846-5p	Homo sapiens	STX1A	6804	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT757523	hsa-miR-6848-5p	Homo sapiens	STX1A	6804	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT758473	hsa-miR-6883-5p	Homo sapiens	STX1A	6804	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT759398	hsa-miR-7515	Homo sapiens	STX1A	6804	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT759306	hsa-miR-7160-3p	Homo sapiens	STX1A	6804	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625

Gene Ontology

ID	GO ID	GO Term	GO Type
6804	GO:0016081	synaptic vesicle docking	GOTERM_BP_DIRECT
6804	GO:0017157	regulation of exocytosis	GOTERM_BP_DIRECT
6804	GO:0061025	membrane fusion	GOTERM_BP_DIRECT
6804	GO:0001948	glycoprotein binding	GOTERM_MF_DIRECT
6804	GO:2000463	positive regulation of excitatory postsynaptic potential	GOTERM_BP_DIRECT
6804	GO:0010807	regulation of synaptic vesicle priming	GOTERM_BP_DIRECT
6804	GO:0019900	kinase binding	GOTERM_MF_DIRECT
6804	GO:0019869	IgG binding	GOTERM_MF_DIRECT
6804	GO:0001956	positive regulation of neurotransmitter secretion	GOTERM_BP_DIRECT
6804	GO:0006886	intracellular protein transport	GOTERM_BP_DIRECT
6804	GO:0033605	positive regulation of catecholamine secretion	GOTERM_BP_DIRECT
6804	GO:0031629	synaptic vesicle fusion to presynaptic active zone membrane	GOTERM_BP_DIRECT
6804	GO:0007269	neurotransmitter secretion	GOTERM_BP_DIRECT
6804	GO:0032940	secretion by cell	GOTERM_BP_DIRECT
6804	GO:0000149	microfilament motor activity	GOTERM_MF_DIRECT
6804	GO:0017022	myosin binding	GOTERM_MF_DIRECT
6804	GO:0014047	glutamate secretion	GOTERM_BP_DIRECT
6804	GO:0005484	sodium:potassium-exchanging ATPase activity	GOTERM_MF_DIRECT
6804	GO:0005829	cytosol	GOTERM_CC_DIRECT
6804	GO:0048278	vesicle docking	GOTERM_BP_DIRECT
6804	GO:0009629	response to gravity	GOTERM_BP_DIRECT
6804	GO:0008076	voltage-gated potassium channel complex	GOTERM_CC_DIRECT
6804	GO:0016192	vesicle-mediated transport	GOTERM_BP_DIRECT
6804	GO:0050796	regulation of insulin secretion	GOTERM_BP_DIRECT
6804	GO:0046982	protein heterodimerization activity	GOTERM_MF_DIRECT
6804	GO:0030141	secretory granule	GOTERM_CC_DIRECT
6804	GO:0043005	neuron projection	GOTERM_CC_DIRECT
6804	GO:0045956	positive regulation of calcium ion-dependent exocytosis	GOTERM_BP_DIRECT
6804	GO:0005515	protein binding	GOTERM_MF_DIRECT
6804	GO:0010701	positive regulation of norepinephrine secretion	GOTERM_BP_DIRECT
6804	GO:0019855	retinol binding	GOTERM_MF_DIRECT
6804	GO:0048306	calcium-dependent protein binding	GOTERM_MF_DIRECT
6804	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex	GOTERM_CC_DIRECT
6804	GO:0008021	synaptic vesicle	GOTERM_CC_DIRECT
6804	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex	GOTERM_CC_DIRECT
6804	GO:0005576	extracellular region	GOTERM_CC_DIRECT
6804	GO:0005886	plasma membrane	GOTERM_CC_DIRECT
6804	GO:0043008	histone deacetylase binding	GOTERM_MF_DIRECT
6804	GO:0044325	ion channel binding	GOTERM_MF_DIRECT
6804	GO:0030054	cell junction	GOTERM_CC_DIRECT
6804	GO:0030672	synaptic vesicle membrane	GOTERM_CC_DIRECT
6804	GO:0030674	protein binding	GOTERM_MF_DIRECT
6804	GO:0047485	protein N-terminus binding	GOTERM_MF_DIRECT
6804	GO:0042641	actomyosin	GOTERM_CC_DIRECT
6804	GO:0031201	SNARE complex	GOTERM_CC_DIRECT
6804	GO:0019904	protein domain specific binding	GOTERM_MF_DIRECT
6804	GO:0005622	intracellular	GOTERM_CC_DIRECT
6804	GO:0032028	thioesterase binding	GOTERM_MF_DIRECT
6804	GO:0016021	integral component of membrane	GOTERM_CC_DIRECT
6804	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex	GOTERM_CC_DIRECT

Pathways

Human Entrez ID	KEGG ID	KEGG Term
6804	hsa04130	SNARE interactions in vesicular transport
6804	hsa04721	Synaptic vesicle cycle
6804	hsa04911	Insulin secretion
6804	hsa05031	Amphetamine addiction

Association with Disease

Protein Official Symbol	Human Entrez ID	Disease Name	Disease Id	Disease Semantic Type	Semantic score	DSI	DPI	Disease Type
STX1A	6804	Autistic Disorder	C0004352	Mental or Behavioral Dysfunction	0.32	0.652	0.621	group
STX1A	6804	Cystic Fibrosis	C0010674	Disease or Syndrome	0.31	0.652	0.621	disease
STX1A	6804	Schizophrenia	C0036341	Mental or Behavioral Dysfunction	0.32	0.652	0.621	disease

Association with Drug

Protein Official Symbol	Human Entrez ID	drug_claim_primary_name	drug_name	drug_chembl_id	interaction_types