ALTITUDEOMICSDB

Cullin 3

AltitudeomicsDB

Protein Official symbol	CUL3
Aliases	CUL3 KIAA0617
Chromosomal Location	2
Length	768
Uniprot ID	Q13618
EC number	None
Protein family Information(Pfam)	PF00888;PF10557;
PDB id	2MYL;2MYM;4AP2;4APF;4EOZ;4HXI;5NLB;6I2M;
InterPro ID	IPR016157;IPR016158;IPR036317;IPR001373;IPR019559;IPR016159;IPR036388;IPR036390;
dbSNP	rs2969802 rs17480168 rs199469656 rs199469658 rs3738952 rs763087632

Protein Protein Interaction

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AltitudeomicsDB

Protein 1	Protein 2	Combine Score
COPS8	COPS6	0.999
DCUN1D1	UBE2M	0.999
UBE2M	NEDD8	0.999
UBA3	NEDD8	0.999
TCEB1	RBX1	0.999
COPS2	COPS4	0.999
GPS1	COPS2	0.999
COPS7A	COPS8	0.999
COPS5	COPS4	0.999
SPOP	CUL3	0.999
GPS1	COPS4	0.999
COPS8	COPS2	0.999
UBE2M	RBX1	0.999
COPS5	COPS6	0.999
UBA3	UBE2M	0.999
COPS8	COPS4	0.999
NEDD8	RBX1	0.999
COPS5	COPS8	0.999
GPS1	COPS6	0.999
TCEB1	TCEB2	0.999
CAND1	RBX1	0.999
COPS5	COPS2	0.999
SKP2	RBX1	0.999
COPS7A	COPS5	0.999
UBE2D2	ANAPC11	0.999
COPS6	COPS2	0.999
FBXW7	SKP1	0.999
KLHL3	CUL3	0.999
COPS7A	COPS6	0.999
DCUN1D1	NEDD8	0.999
SKP2	SKP1	0.999
COPS7A	COPS4	0.999
COPS7A	COPS2	0.999
COPS7A	GPS1	0.999
GPS1	COPS5	0.999
COPS6	COPS4	0.999
GPS1	COPS8	0.999
SKP1	RBX1	0.999
DCUN1D1	RBX1	0.999
CUL3	KEAP1	0.999
UBE2F	RNF7	0.998
CUL3	RBX1	0.998
KLHL11	CUL3	0.998
UBE2F	DCUN1D3	0.998
TCEB1	RNF7	0.997
UBE2F	UBA3	0.997
COPS5	CUL3	0.997
CUL3	NEDD8	0.997
FBXW7	RBX1	0.996
CUL3	UBE2M	0.996
UBE2F	NEDD8	0.996
TCEB1	NEDD8	0.996
RNF7	NEDD8	0.995
RBX1	CDC34	0.995
CUL3	SKP1	0.995
KLHL9	CUL3	0.995
KLHL13	CUL3	0.995
RNF7	UBE2M	0.995
TCEB2	RBX1	0.995
UBE2D2	UBA1	0.995
ANAPC11	RNF7	0.994
DCUN1D2	UBE2M	0.994
COPS5	NEDD8	0.994
RNF7	SKP1	0.994
COPS5	SKP1	0.994
UBE2F	RBX1	0.993
BTRC	SKP1	0.993
UBE2D1	UBA1	0.993
KLHL2	CUL3	0.993
SKP1	CDC34	0.993
ANAPC11	RBX1	0.993
CAND1	CUL3	0.993
DCUN1D2	NEDD8	0.992
RNF7	CUL3	0.992
UBA1	CDC34	0.992
CUL3	COPS4	0.992
DCUN1D1	CUL3	0.991
SPOPL	CUL3	0.991
CAND1	RNF7	0.991
DCUN1D2	RBX1	0.991
CAND1	NEDD8	0.991
KLHL12	CUL3	0.991
COPS6	NEDD8	0.99
TCEB1	CUL3	0.99
RNF7	TCEB2	0.99
BTRC	SKP2	0.99
UBE2F	DCUN1D1	0.989
FBXW7	CDC34	0.988
KLHL13	AURKB	0.988
UBE2F	DCUN1D5	0.988
DCUN1D3	UBE2M	0.988
DCUN1D5	UBE2M	0.987
COPS4	NEDD8	0.987
UBE2F	CUL3	0.987
GPS1	CUL3	0.987
NEDD8	SKP1	0.987
DCUN1D2	CUL3	0.986
CAND1	UBE2M	0.986
TCEB1	SKP1	0.986
AURKB	CUL3	0.986
UBA1	UBE2M	0.985
RNF7	CDC34	0.984
TCEB2	NEDD8	0.984
KLHL21	CUL3	0.984
DCUN1D1	RNF7	0.984
UBE2D1	RBX1	0.984
RBX1	KEAP1	0.983
UBA3	CUL3	0.983
UBA3	RBX1	0.983
UBE2D2	RBX1	0.983
UBE2D1	ANAPC11	0.983
COPS5	RBX1	0.983
BTRC	RBX1	0.983
CUL3	KLHL20	0.983
CAND1	DCUN1D1	0.983
CUL7	RBX1	0.983
CAND1	SKP1	0.982
SKP2	CUL3	0.982
TCEB1	ANAPC11	0.982
COPS6	CUL3	0.982
ANAPC11	SKP1	0.981
BTBD6	CUL3	0.981
UBE2D2	UBE2D1	0.981
CUL7	SKP1	0.981
DCUN1D5	RBX1	0.981
SKP2	RNF7	0.981
DCUN1D3	RBX1	0.981
KLHL9	AURKB	0.981
KLHL22	CUL3	0.981
KLHL2	KLHL3	0.98
UBE2D2	NEDD8	0.98
DCUN1D5	NEDD8	0.98
KBTBD13	CUL3	0.98
TCEB1	COPS5	0.98
UBE2F	DCUN1D2	0.979
CAND1	DCUN1D3	0.979
UBA3	DCUN1D1	0.978
RNF7	DCUN1D5	0.978
GLI2	SPOP	0.978
UBE2D1	SKP1	0.977
UBE2D2	CUL3	0.977
CUL3	CDC34	0.977
KLHL42	CUL3	0.977
DCUN1D3	NEDD8	0.977
COPS2	CUL3	0.977
UBA3	RNF7	0.977
CUL3	DCUN1D5	0.976
GAN	UBA1	0.976
CUL3	TCEB2	0.976
KLHL25	CUL3	0.976
COPS2	NEDD8	0.976
DCUN1D3	RNF7	0.975
UBE2D1	CUL3	0.975
DCUN1D2	RNF7	0.975
ANAPC11	CUL3	0.975
COPS7A	CUL3	0.974
DCUN1D3	CUL3	0.974
CUL7	CUL3	0.973
GLI2	CUL3	0.973
FBXW7	SKP2	0.973
BTRC	CDC34	0.973
KCTD6	CUL3	0.973
SKP2	NEDD8	0.973
FBXW7	CUL3	0.972
GAN	CUL3	0.972
UBA1	RBX1	0.972
UBE2M	SKP1	0.971
UBA3	CDC34	0.971
COPS8	CUL3	0.971
UBE2F	UBA1	0.971
COPS8	NEDD8	0.971
COPS5	DCUN1D1	0.971
UBE2D1	RNF7	0.971
UBE2D2	RNF7	0.97
UBA1	CUL3	0.97
SKP2	CDC34	0.97
TCEB2	SKP1	0.97
COPS5	SKP2	0.969
BTRC	CUL3	0.969
COPS6	RBX1	0.969
CUL7	UBA3	0.969
UBA3	DCUN1D5	0.969
CAND1	DCUN1D5	0.968
UBE2D1	NEDD8	0.968
GLI2	BTRC	0.968
UBA1	SKP1	0.967
COPS5	RNF7	0.967
UBA3	SKP1	0.967
COPS7A	NEDD8	0.966
UBE2D1	BTRC	0.966
TCEB1	UBA3	0.966
COPS4	RBX1	0.966
BTRC	RNF7	0.965
UBE2F	CAND1	0.965
COPS2	RBX1	0.965
UBE2D2	BTRC	0.964
SPOP	RBX1	0.963
UBE2D2	SKP1	0.963
GPS1	NEDD8	0.963
ANAPC11	TCEB2	0.962
COPS4	SKP1	0.962
KLHL3	RBX1	0.962
CUL7	NEDD8	0.962
COPS6	SKP1	0.961
BTRC	NEDD8	0.961
COPS7A	RBX1	0.961
CAND1	TCEB2	0.96
TCEB1	SKP2	0.96
UBE2D2	UBA3	0.96
CUL7	UBE2M	0.96
CUL7	FBXW7	0.959
CAND1	SKP2	0.959
GPS1	RBX1	0.959
FBXW7	NEDD8	0.959
CAND1	DCUN1D2	0.959
CUL7	RNF7	0.959
TCEB1	CAND1	0.958
DCUN1D2	UBA3	0.958
DCUN1D2	COPS5	0.956
ANAPC11	CDC34	0.955
KLHL13	COPS4	0.955
ANAPC11	UBE2M	0.955
COPS5	FBXW7	0.955
KLHL13	KLHL22	0.955
ANAPC11	SKP2	0.954
COPS5	DCUN1D5	0.954
KLHL13	COPS2	0.954
UBA1	RNF7	0.954
KLHL21	UBA3	0.954
FBXW7	RNF7	0.953
KLHL13	KLHL9	0.953
COPS5	KLHL22	0.952
ANAPC11	FBXW7	0.952
BTRC	COPS6	0.951
KLHL3	KEAP1	0.951
TCEB1	CDC34	0.951
COPS8	RBX1	0.95
COPS6	SKP2	0.95
CAND1	BTRC	0.949
COPS8	SKP1	0.949
UBE2F	SKP1	0.949
CAND1	FBXW7	0.949
COPS2	DCUN1D5	0.948
COPS5	DCUN1D3	0.948
UBA3	DCUN1D3	0.948
UBE2F	ANAPC11	0.948
UBE2D1	KLHL9	0.948
TCEB1	CUL7	0.947
KLHL13	UBE2D1	0.947
UBA3	SKP2	0.947
KLHL21	KLHL9	0.947
KLHL13	KLHL21	0.946
GAN	RBX1	0.946
CUL7	SKP2	0.945
UBE2D1	UBA3	0.945
KLHL2	SKP1	0.945
UBE2D2	UBE2M	0.945
GLI2	SPOPL	0.944
TCEB1	UBE2D1	0.944
SKP2	TCEB2	0.943
KLHL21	RBX1	0.943
KLHL11	RBX1	0.943
CUL7	TCEB2	0.942
GPS1	SKP1	0.942
KLHL2	KEAP1	0.942
KLHL2	RBX1	0.942
UBE2F	UBE2D2	0.942
KLHL21	UBA1	0.942
SKP2	UBE2M	0.941
KLHL2	UBA1	0.941
UBA1	SKP2	0.941
DCUN1D3	SKP2	0.941
KLHL9	RBX1	0.94
GPS1	SKP2	0.94
COPS6	DCUN1D1	0.94
UBA1	FBXW7	0.94
UBE2M	CDC34	0.94
UBE2F	CUL7	0.939
CUL7	KCTD6	0.939
KLHL9	KLHL22	0.939
KLHL2	UBE2D1	0.939
KLHL13	COPS5	0.939
KLHL21	NEDD8	0.938
KLHL12	RBX1	0.938
CAND1	KLHL3	0.938
TCEB1	UBA1	0.938
BTRC	KEAP1	0.938
UBE2D2	KLHL21	0.937
TCEB1	UBE2D2	0.937
TCEB1	FBXW7	0.937
KLHL11	SKP1	0.937
ANAPC11	UBA1	0.937
BTRC	COPS5	0.937
CUL7	ANAPC11	0.937
TCEB2	CDC34	0.936
RNF7	COPS4	0.936
BTRC	ANAPC11	0.935
TCEB1	DCUN1D1	0.935
UBE2F	TCEB1	0.935
TCEB2	UBE2M	0.935
CUL7	BTRC	0.935
UBA1	TCEB2	0.934
CUL7	CDC34	0.934
NEDD8	KEAP1	0.934
TCEB1	COPS4	0.934
DCUN1D1	SKP1	0.934
KLHL42	KLHL11	0.933
KLHL13	NEDD8	0.933
UBA3	COPS5	0.933
BTRC	UBE2M	0.933
CUL7	KLHL25	0.932
UBE2D1	SKP2	0.932
GPS1	RNF7	0.932
KLHL3	NEDD8	0.931
COPS5	UBE2M	0.931
COPS6	RNF7	0.931
COPS8	SKP2	0.931
UBE2F	TCEB2	0.931
BTRC	COPS2	0.93
UBA3	UBA1	0.93
SKP1	KEAP1	0.93
KLHL42	KLHL9	0.93
COPS5	TCEB2	0.93
RBX1	KLHL20	0.93
FBXW7	KEAP1	0.93
SPOPL	RBX1	0.929
KLHL3	UBE2M	0.929
TCEB1	KLHL2	0.929
KLHL13	KLHL42	0.929
UBE2D2	SKP2	0.929
UBE2F	CDC34	0.929
CUL7	KLHL2	0.929
COPS7A	SKP1	0.929
KLHL9	KLHL11	0.929
DCUN1D3	DCUN1D5	0.929
CAND1	BTBD6	0.929
TCEB1	DCUN1D5	0.929
UBE2F	SKP2	0.928
FBXW7	TCEB2	0.928
TCEB1	COPS6	0.928
KLHL2	KBTBD13	0.928
DCUN1D1	SKP2	0.928
KLHL9	NEDD8	0.928
KLHL13	KLHL11	0.928
KLHL42	SKP1	0.928
KLHL13	RBX1	0.928
BTRC	FBXW7	0.928
KLHL22	NEDD8	0.927
UBE2D1	TCEB2	0.927
ANAPC11	AURKB	0.927
KLHL11	NEDD8	0.927
KLHL21	CDC34	0.927
UBE2D1	FBXW7	0.927
UBA3	KLHL3	0.927
DCUN1D2	DCUN1D5	0.927
UBE2D2	KLHL9	0.926
UBE2D2	TCEB2	0.926
CUL7	KLHL3	0.926
KCTD6	NEDD8	0.926
CAND1	KEAP1	0.926
KLHL42	NEDD8	0.926
COPS8	RNF7	0.926
DCUN1D1	TCEB2	0.926
KLHL13	CDC34	0.926
COPS7A	BTRC	0.926
TCEB1	DCUN1D2	0.925
NEDD8	KLHL20	0.925
GLI2	SKP1	0.925
DCUN1D1	DCUN1D5	0.925
KLHL3	RNF7	0.925
COPS7A	SKP2	0.925
DCUN1D3	SKP1	0.925
COPS6	TCEB2	0.925
DCUN1D2	UBE2D1	0.925
TCEB1	KLHL11	0.925
KLHL22	KLHL20	0.924
KLHL13	UBA1	0.924
KLHL2	UBA3	0.924
KLHL42	KLHL21	0.924
COPS4	TCEB2	0.924
TCEB1	UBE2M	0.924
BTRC	UBA3	0.924
COPS8	TCEB2	0.924
KLHL21	KLHL22	0.923
UBE2D2	KLHL3	0.923
DCUN1D3	DCUN1D1	0.923
KLHL11	KLHL3	0.923
COPS6	FBXW7	0.923
KLHL25	RBX1	0.923
KLHL9	SKP1	0.923
GAN	KLHL11	0.923
BTRC	COPS4	0.923
DCUN1D2	COPS6	0.923
UBA3	ANAPC11	0.923
DCUN1D2	TCEB2	0.922
KLHL22	RBX1	0.922
KLHL3	DCUN1D5	0.922
DCUN1D2	DCUN1D3	0.922
DCUN1D3	COPS6	0.922
SKP2	COPS4	0.922
COPS2	RNF7	0.921
DCUN1D2	SKP1	0.921
COPS2	SKP1	0.921
COPS2	DCUN1D1	0.921
COPS7A	RNF7	0.921
DCUN1D2	SKP2	0.921
CUL7	UBA1	0.921
UBE2M	KEAP1	0.92
KLHL21	UBE2D1	0.92
KLHL13	UBE2D2	0.92
KLHL2	NEDD8	0.92
TCEB1	KEAP1	0.92
KBTBD13	RBX1	0.92
TCEB1	DCUN1D3	0.92
FBXW7	COPS4	0.92
CDC34	KEAP1	0.919
KLHL21	DCUN1D1	0.919
UBE2D2	CDC34	0.919
UBE2M	KLHL20	0.919
FBXW7	UBE2M	0.919
CUL7	KLHL20	0.919
CAND1	KLHL9	0.919
COPS5	KCTD6	0.919
UBA3	TCEB2	0.919
TCEB1	KLHL25	0.919
GAN	KLHL42	0.919
RNF7	RBX1	0.919
KLHL3	SKP2	0.919
GAN	KLHL2	0.918
TCEB1	BTRC	0.918
UBE2D1	CDC34	0.918
DCUN1D3	TCEB2	0.918
COPS5	KEAP1	0.918
UBE2D2	FBXW7	0.918
UBE2F	BTRC	0.918
TCEB1	KLHL3	0.918
BTRC	TCEB2	0.917
UBE2D1	KLHL20	0.917
TCEB1	COPS8	0.917
BTRC	UBA1	0.917
CUL7	UBE2D1	0.917
GAN	KLHL9	0.917
KLHL25	KLHL11	0.917
UBA1	KLHL3	0.917
KLHL42	COPS5	0.917
KLHL2	DCUN1D5	0.917
COPS6	DCUN1D5	0.917
UBE2D2	KLHL11	0.916
UBE2F	UBE2M	0.916
KLHL42	KLHL25	0.916
BTBD6	SKP1	0.916
KCTD6	SKP1	0.916
KLHL21	UBE2M	0.916
UBE2D2	KLHL22	0.916
GPS1	BTRC	0.916
DCUN1D1	COPS4	0.916
KLHL13	KLHL2	0.916
SKP2	KEAP1	0.916
KLHL2	KLHL9	0.916
UBE2D2	DCUN1D1	0.915
KCTD6	COPS8	0.915
KLHL2	KLHL11	0.915
GAN	BTBD6	0.915
GAN	NEDD8	0.915
KLHL11	KEAP1	0.915
KLHL9	RNF7	0.915
GAN	SKP2	0.915
TCEB1	KLHL9	0.915
KLHL13	KLHL25	0.915
UBA3	FBXW7	0.914
SKP2	DCUN1D5	0.914
KBTBD13	SKP1	0.914
UBE2D2	KLHL20	0.914
KLHL9	UBA1	0.914
KLHL3	SKP1	0.914
KLHL9	KLHL3	0.914
DCUN1D5	SKP1	0.914
DCUN1D1	FBXW7	0.914
RNF7	KEAP1	0.914
GAN	KLHL13	0.914
KCTD6	UBE2M	0.914
UBA3	KLHL22	0.914
CAND1	KLHL42	0.914
TCEB2	KEAP1	0.914
UBE2D1	KEAP1	0.914
UBE2F	KLHL3	0.913
TCEB1	BTBD6	0.913
UBE2D2	KEAP1	0.913
KLHL42	COPS4	0.913
KLHL2	KCTD6	0.913
GAN	KLHL3	0.913
CUL7	KLHL9	0.913
UBE2D1	UBE2M	0.913
BTBD6	GPS1	0.913
UBE2D1	AURKB	0.913
KLHL11	RNF7	0.913
KBTBD13	KLHL3	0.913
COPS2	SKP2	0.912
UBE2D1	KLHL11	0.912
KLHL2	KLHL22	0.912
KLHL9	KLHL20	0.912
DCUN1D2	COPS2	0.912
KLHL11	SKP2	0.912
CAND1	KLHL2	0.912
BTBD6	KLHL9	0.912
UBE2D1	KCTD6	0.912
CUL7	KEAP1	0.912
KCTD6	CDC34	0.912
KLHL13	RNF7	0.912
KLHL22	KLHL3	0.912
KLHL21	RNF7	0.912
BTBD6	TCEB2	0.912
UBE2D2	KCTD6	0.912
KBTBD13	KLHL20	0.912
CUL7	KLHL22	0.912
COPS8	FBXW7	0.912
BTBD6	FBXW7	0.911
DCUN1D2	UBE2D2	0.911
KLHL2	UBE2D2	0.911
KLHL2	SKP2	0.911
SKP1	KLHL20	0.911
CDC34	KLHL20	0.911
KLHL3	DCUN1D1	0.911
GPS1	DCUN1D1	0.911
KLHL3	CDC34	0.911
KBTBD13	UBE2D1	0.911
GAN	KBTBD13	0.911
UBA3	KEAP1	0.91
KLHL2	KLHL42	0.91
UBA1	KEAP1	0.91
KLHL22	CDC34	0.91
UBE2D1	DCUN1D1	0.91
KLHL13	SKP1	0.91
DCUN1D3	COPS4	0.91
KLHL9	KLHL25	0.91
KLHL42	KLHL20	0.91
GAN	KEAP1	0.91
KLHL9	COPS5	0.91
KLHL11	KLHL20	0.91
UBE2D1	KLHL3	0.91
TCEB1	COPS7A	0.91
KLHL25	CDC34	0.91
CAND1	KLHL11	0.91
KLHL2	RNF7	0.91
COPS7A	KEAP1	0.909
KLHL21	SKP1	0.909
CAND1	KLHL20	0.909
DCUN1D3	COPS2	0.909
FBXW7	KLHL20	0.909
GAN	SKP1	0.909
KLHL2	UBE2M	0.909
KLHL13	COPS6	0.909
KLHL9	SKP2	0.909
KLHL20	KEAP1	0.909
KLHL9	CDC34	0.909
GAN	CUL7	0.909
KLHL42	COPS6	0.909
KLHL9	KEAP1	0.909
KLHL13	KLHL3	0.909
KLHL2	COPS4	0.909
KLHL9	COPS6	0.909
GPS1	TCEB2	0.909
KLHL22	UBE2M	0.909
COPS7A	DCUN1D3	0.909
UBE2F	UBE2D1	0.909
BTRC	COPS8	0.909
TCEB2	DCUN1D5	0.909
GPS1	FBXW7	0.908
KLHL22	SKP2	0.908
COPS6	KLHL20	0.908
KLHL2	CDC34	0.908
RNF7	KLHL20	0.908
UBA3	KLHL20	0.908
GAN	KLHL20	0.908
GAN	RNF7	0.908
BTBD6	KLHL22	0.908
KLHL2	KLHL20	0.908
KLHL42	UBE2M	0.908
UBE2D1	KLHL22	0.908
COPS7A	FBXW7	0.908
KLHL21	KLHL25	0.908
KLHL22	COPS6	0.908
TCEB1	COPS2	0.908
GAN	UBA3	0.908
KLHL13	CUL7	0.908
CUL7	KLHL11	0.908
UBE2F	FBXW7	0.908
SKP2	KLHL20	0.908
UBA3	KLHL9	0.907
UBE2D1	KLHL25	0.907
CUL7	KLHL42	0.907
UBE2F	KLHL20	0.907
KLHL2	COPS5	0.907
GAN	CDC34	0.907
KLHL13	COPS7A	0.907
COPS2	FBXW7	0.907
CAND1	KLHL21	0.907
GAN	KLHL25	0.907
KLHL25	SKP2	0.907
UBE2D2	KLHL25	0.907
GAN	UBE2D2	0.907
TCEB1	KLHL20	0.907
KBTBD13	NEDD8	0.907
KLHL3	KLHL20	0.907
KLHL42	RBX1	0.907
GAN	UBE2D1	0.907
KLHL22	KLHL11	0.907
COPS2	TCEB2	0.907
UBA1	KLHL22	0.906
GPS1	DCUN1D5	0.906
COPS7A	DCUN1D1	0.906
KBTBD13	KLHL9	0.906
KLHL9	COPS4	0.906
KLHL13	UBE2M	0.906
GAN	UBE2M	0.906
TCEB1	GAN	0.906
GLI2	RBX1	0.906
KLHL13	KBTBD13	0.906
TCEB1	KLHL13	0.906
KLHL21	KEAP1	0.906
KLHL21	KLHL20	0.906
DCUN1D2	GPS1	0.906
UBE2D2	DCUN1D5	0.906
UBE2F	KLHL2	0.906
KLHL25	SKP1	0.906
GPS1	DCUN1D3	0.906
COPS8	DCUN1D1	0.906
KLHL2	ANAPC11	0.906
COPS8	KEAP1	0.906
BTBD6	KLHL11	0.906
UBE2D2	KLHL42	0.906
TCEB1	KLHL21	0.905
KBTBD13	CDC34	0.905
DCUN1D1	KEAP1	0.905
KLHL25	UBE2M	0.905
KLHL42	KEAP1	0.905
KLHL21	SKP2	0.905
BTRC	DCUN1D1	0.905
KLHL13	CAND1	0.905
UBA1	KLHL20	0.905
KLHL2	BTRC	0.905
KLHL11	FBXW7	0.905
KLHL21	KLHL11	0.905
KLHL13	ANAPC11	0.905
KLHL25	RNF7	0.905
BTBD6	KLHL21	0.905
KLHL13	COPS8	0.905
CUL7	UBE2D2	0.905
KLHL42	KLHL3	0.905
COPS8	DCUN1D5	0.905
TCEB1	KLHL22	0.905
KCTD6	COPS6	0.905
KLHL42	CDC34	0.905
BTBD6	CDC34	0.905
KBTBD13	UBE2D2	0.905
GPS1	KEAP1	0.905
COPS8	DCUN1D3	0.905
KLHL42	UBE2D1	0.905
KLHL11	CDC34	0.905
KLHL2	KLHL25	0.905
KLHL9	COPS8	0.905
KLHL22	KEAP1	0.905
KBTBD13	KEAP1	0.904
UBE2F	KLHL11	0.904
TCEB1	KLHL42	0.904
KLHL13	UBA3	0.904
TCEB2	KLHL20	0.904
UBE2D1	DCUN1D5	0.904
UBE2F	KLHL21	0.904
KLHL13	TCEB2	0.904
KLHL2	FBXW7	0.904
BTRC	KLHL20	0.904
UBE2F	KEAP1	0.904
KLHL22	SKP1	0.904
BTBD6	UBE2M	0.904
DCUN1D2	KEAP1	0.904
GAN	KLHL22	0.904
DCUN1D3	KEAP1	0.904
KLHL2	BTBD6	0.904
ANAPC11	KEAP1	0.904
KLHL21	ANAPC11	0.904
COPS5	KLHL3	0.904
KLHL13	KEAP1	0.904
KLHL11	TCEB2	0.904
DCUN1D2	COPS4	0.904
DCUN1D2	FBXW7	0.904
ANAPC11	KLHL20	0.904
KLHL2	COPS6	0.903
KLHL3	TCEB2	0.903
GAN	DCUN1D1	0.903
DCUN1D3	FBXW7	0.903
KLHL42	TCEB2	0.903
KLHL2	KLHL21	0.903
TCEB1	GPS1	0.903
KLHL42	RNF7	0.903
BTBD6	RBX1	0.903
KCTD6	UBA1	0.903
COPS4	DCUN1D5	0.903
KLHL22	RNF7	0.903
COPS5	KLHL20	0.903
KLHL2	TCEB2	0.903
COPS7A	KLHL21	0.902
UBA3	KLHL11	0.902
FBXW7	DCUN1D5	0.902
COPS7A	DCUN1D5	0.902
KLHL9	COPS2	0.902
KLHL2	DCUN1D3	0.902
KCTD6	RNF7	0.902
COPS7A	TCEB2	0.902
BTBD6	DCUN1D1	0.902
DCUN1D2	BTBD6	0.902
KLHL42	KLHL22	0.902
GAN	ANAPC11	0.902
KLHL25	KEAP1	0.902
GAN	CAND1	0.902
COPS6	KEAP1	0.902
ANAPC11	KLHL3	0.902
BTBD6	COPS5	0.902
KLHL25	KLHL22	0.902
KLHL22	COPS4	0.902
BTRC	DCUN1D3	0.902
DCUN1D2	KLHL21	0.902
ANAPC11	KLHL22	0.902
BTBD6	UBA3	0.902
BTRC	KLHL25	0.902
KLHL21	COPS4	0.902
GAN	COPS4	0.902
GPS1	KLHL25	0.902
KBTBD13	KLHL21	0.902
KLHL13	SKP2	0.902
KLHL21	COPS5	0.902
KLHL13	BTBD6	0.902
UBE2F	BTBD6	0.902
KBTBD13	KLHL25	0.902
DCUN1D2	BTRC	0.902
KBTBD13	RNF7	0.902
KLHL11	COPS6	0.902
COPS4	KLHL20	0.902
COPS4	KEAP1	0.902
BTBD6	ANAPC11	0.902
BTBD6	RNF7	0.902
BTBD6	COPS6	0.902
ANAPC11	KLHL25	0.902
COPS2	KLHL20	0.902
UBA3	KCTD6	0.902
BTBD6	UBA1	0.902
DCUN1D3	KLHL3	0.902
KLHL13	KLHL20	0.902
COPS7A	KLHL22	0.902
KLHL25	NEDD8	0.902
BTBD6	KEAP1	0.902
UBA3	KLHL25	0.902
KBTBD13	KLHL22	0.902
KLHL3	COPS4	0.902
COPS5	KLHL11	0.902
CAND1	KLHL22	0.902
BTBD6	BTRC	0.902
KLHL9	DCUN1D5	0.902
COPS7A	DCUN1D2	0.902
GPS1	KLHL11	0.902
KBTBD13	COPS5	0.902
BTBD6	KLHL20	0.902
KBTBD13	COPS6	0.902
KLHL9	ANAPC11	0.902
COPS7A	BTBD6	0.902
COPS7A	KCTD6	0.902
KLHL25	COPS4	0.902
CAND1	KCTD6	0.901
BTRC	KLHL3	0.901
KBTBD13	COPS2	0.901
DCUN1D3	KLHL11	0.901
KLHL9	DCUN1D3	0.901
KLHL25	KLHL20	0.901
KLHL11	COPS2	0.901
CUL7	KBTBD13	0.901
KLHL13	BTRC	0.901
KLHL25	KLHL3	0.901
KLHL13	DCUN1D2	0.901
KLHL13	DCUN1D3	0.901
DCUN1D2	DCUN1D1	0.901
COPS2	KEAP1	0.901
GAN	BTRC	0.901
ANAPC11	KLHL11	0.901
CUL7	BTBD6	0.901
KLHL21	BTRC	0.901
BTRC	KCTD6	0.901
DCUN1D2	KLHL9	0.901
DCUN1D3	KLHL20	0.901
GPS1	KLHL42	0.901
DCUN1D2	KLHL20	0.901
SPOP	SPOPL	0.901
BTRC	KLHL22	0.901
DCUN1D5	KEAP1	0.901
KLHL42	COPS2	0.901
KLHL13	DCUN1D5	0.901
KLHL9	DCUN1D1	0.901
BTBD6	KLHL25	0.901
COPS5	KLHL25	0.901
BTRC	KLHL9	0.901
KLHL13	DCUN1D1	0.901
GAN	COPS5	0.901
BTRC	DCUN1D5	0.901
UBA1	KLHL25	0.901
KCTD6	RBX1	0.901
KBTBD13	GPS1	0.901
DCUN1D1	KLHL20	0.901
KLHL42	ANAPC11	0.901
KBTBD13	ANAPC11	0.901
COPS8	KLHL20	0.9
UBE2D2	BTBD6	0.9
KLHL21	KLHL3	0.9
KLHL42	DCUN1D5	0.9
KLHL9	KCTD6	0.9
TCEB1	KCTD6	0.9
KBTBD13	BTRC	0.9
KLHL3	COPS6	0.9
KLHL21	KCTD6	0.9
DCUN1D2	KLHL22	0.9
UBE2F	KBTBD13	0.9
KLHL42	SKP2	0.9
BTBD6	COPS4	0.9
COPS7A	KLHL2	0.9
UBA1	KLHL11	0.9
KLHL22	DCUN1D5	0.9
GAN	KCTD6	0.9
KLHL11	UBE2M	0.9
KLHL21	COPS6	0.9
GAN	TCEB2	0.9
UBE2F	GAN	0.9
BTBD6	DCUN1D5	0.9
KLHL21	COPS2	0.9
KLHL3	COPS2	0.9
KLHL22	DCUN1D3	0.9
KCTD6	COPS2	0.9
KLHL22	COPS2	0.9
BTBD6	COPS2	0.9
COPS7A	KLHL3	0.9
KLHL42	DCUN1D3	0.9
KLHL25	DCUN1D3	0.9
KBTBD13	COPS4	0.9
COPS7A	KLHL9	0.9
GPS1	KLHL3	0.9
KLHL9	TCEB2	0.9
COPS8	KLHL22	0.9
BTBD6	KLHL42	0.9
COPS8	KLHL25	0.9
KLHL42	DCUN1D1	0.9
UBE2F	KLHL42	0.9
KBTBD13	KLHL42	0.9
KBTBD13	DCUN1D5	0.9
UBE2F	KLHL13	0.9
KLHL2	COPS2	0.9
GAN	COPS7A	0.9
KCTD6	KLHL3	0.9
GAN	COPS6	0.9
KLHL3	FBXW7	0.9
KLHL9	UBE2M	0.9
GAN	COPS8	0.9
COPS7A	KLHL25	0.9
GPS1	KCTD6	0.9
KLHL13	KCTD6	0.9
KLHL21	FBXW7	0.9
DCUN1D2	KLHL3	0.9
DCUN1D2	KBTBD13	0.9
KLHL42	UBA3	0.9
GAN	KLHL21	0.9
KCTD6	DCUN1D5	0.9
UBE2F	KLHL9	0.9
KLHL22	DCUN1D1	0.9
CUL7	KLHL21	0.9
BTBD6	NEDD8	0.9
BTBD6	KCTD6	0.9
KCTD6	SKP2	0.9
DCUN1D2	KLHL42	0.9
COPS7A	KBTBD13	0.9
KCTD6	KLHL20	0.9
CAND1	KBTBD13	0.9
KCTD6	DCUN1D3	0.9
DCUN1D2	KLHL25	0.9
KBTBD13	SKP2	0.9
KLHL42	BTRC	0.9
KLHL13	GPS1	0.9
KLHL21	TCEB2	0.9
COPS8	KLHL3	0.9
KBTBD13	DCUN1D1	0.9
KBTBD13	KLHL11	0.9
GPS1	KLHL9	0.9
KBTBD13	UBA1	0.9
GAN	FBXW7	0.9
KBTBD13	UBA3	0.9
KLHL42	KCTD6	0.9
KLHL13	FBXW7	0.9
GAN	DCUN1D3	0.9
KLHL11	DCUN1D1	0.9
KCTD6	TCEB2	0.9
KLHL9	FBXW7	0.9
KBTBD13	FBXW7	0.9
GAN	DCUN1D5	0.9
KLHL2	DCUN1D2	0.9
KLHL25	TCEB2	0.9
CAND1	KLHL25	0.9
KLHL22	FBXW7	0.9
GPS1	KLHL20	0.9
KLHL25	DCUN1D5	0.9
KCTD6	KLHL22	0.9
COPS7A	KLHL11	0.9
KBTBD13	DCUN1D3	0.9
KCTD6	DCUN1D1	0.9
GAN	DCUN1D2	0.9
KCTD6	KLHL25	0.9
KCTD6	FBXW7	0.9
COPS7A	KLHL42	0.9
KLHL25	DCUN1D1	0.9
KCTD6	KEAP1	0.9
TCEB1	KBTBD13	0.9
KLHL11	DCUN1D5	0.9
KLHL42	UBA1	0.9
DCUN1D2	COPS8	0.9
UBE2F	KCTD6	0.9
BTBD6	COPS8	0.9
BTBD6	DCUN1D3	0.9
ANAPC11	KCTD6	0.9
DCUN1D2	KCTD6	0.9
BTRC	KLHL11	0.9
GPS1	KLHL21	0.9
DCUN1D5	KLHL20	0.9
KLHL2	COPS8	0.9
KLHL25	COPS2	0.9
KBTBD13	KCTD6	0.9
KLHL42	FBXW7	0.9
KLHL25	FBXW7	0.9
KLHL42	COPS8	0.9
KBTBD13	UBE2M	0.9
BTBD6	KLHL3	0.9
KBTBD13	TCEB2	0.9
KCTD6	COPS4	0.9
KLHL11	COPS4	0.9
KBTBD13	COPS8	0.9
KLHL25	COPS6	0.9
UBE2F	KLHL25	0.9
GAN	GPS1	0.9
DCUN1D2	KLHL11	0.9
KLHL21	DCUN1D3	0.9
KLHL22	TCEB2	0.9
GAN	COPS2	0.9
KBTBD13	BTBD6	0.9
KLHL21	DCUN1D5	0.9
KLHL21	COPS8	0.9
COPS8	KLHL11	0.9
KCTD6	KLHL11	0.9
BTBD6	SKP2	0.9
BTBD6	UBE2D1	0.9
COPS7A	KLHL20	0.9
GPS1	KLHL22	0.9
KLHL2	GPS1	0.9
UBE2F	KLHL22	0.9
KLHL2	DCUN1D1	0.9

Gene Ontology Semantic Similarity

Download Tab separated file

#	10920 (COPS8)	54165 (DCUN1D1)	9040 (UBE2M)	9039 (UBA3)	6921 (TCEB1)	9318 (COPS2)	2873 (GPS1)	50813 (COPS7A)	10987 (COPS5)	8405 (SPOP)	4738 (NEDD8)	55832 (CAND1)	6502 (SKP2)	7322 (UBE2D2)	10980 (COPS6)	55294 (FBXW7)	26249 (KLHL3)	6500 (SKP1)	8452 (CUL3)	140739 (UBE2F)	9616 (RNF7)	9978 (RBX1)	55958 (KLHL9)	90293 (KLHL13)	6923 (TCEB2)	51529 (ANAPC11)	55208 (DCUN1D2)	8945 (BTRC)	7321 (UBE2D1)	11275 (KLHL2)	7317 (UBA1)	339745 (SPOPL)	59349 (KLHL12)	123879 (DCUN1D3)	84259 (DCUN1D5)	51138 (COPS4)	9212 (AURKB)	9903 (KLHL21)	9820 (CUL7)	84861 (KLHL22)	2736 (GLI2)	57542 (KLHL42)	8139 (GAN)	200845 (KCTD6)	997 (CDC34)	27252 (KLHL20)	9817 (KEAP1)
10920 (COPS8)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.18	0.18	1.00	0.82	0.82	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.18	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00
54165 (DCUN1D1)	1.00	1.00	0.66	0.68	0.74	0.74	0.73	1.00	0.51	0.81	0.74	1.00	0.67	0.64	1.00	0.69	0.76	0.74	0.65	0.65	0.67	0.62	0.18	0.18	0.81	0.55	0.97	0.63	0.64	0.82	0.68	0.81	0.84	0.94	0.94	0.73	0.59	0.18	1.00	0.84	0.60	0.74	0.79	0.87	0.65	0.72	0.84
9040 (UBE2M)	1.00	0.66	1.00	0.81	0.94	0.51	0.50	1.00	0.40	0.59	0.57	1.00	0.90	0.87	1.00	0.76	0.56	0.88	0.83	0.91	0.83	0.88	1.00	1.00	0.59	0.83	0.56	0.83	0.87	0.64	0.51	0.59	0.64	0.67	0.67	0.51	0.53	1.00	1.00	0.64	0.47	0.94	0.63	0.67	0.91	0.88	0.64
9039 (UBA3)	1.00	0.68	0.81	1.00	0.74	0.58	0.57	1.00	0.46	0.64	0.61	1.00	0.76	0.70	1.00	0.71	0.61	0.74	0.70	0.81	0.74	0.75	0.70	0.70	0.64	0.61	0.57	0.68	0.70	0.72	0.70	0.64	0.72	0.68	0.68	0.58	0.56	0.70	1.00	0.67	0.52	0.74	0.66	0.73	0.71	0.72	0.67
6921 (TCEB1)	1.00	0.74	0.94	0.74	1.00	0.59	0.58	1.00	0.42	0.70	0.64	1.00	0.93	0.90	1.00	0.76	0.64	0.90	0.84	0.79	0.77	0.84	1.00	1.00	0.70	0.85	0.64	0.85	0.90	0.74	0.57	0.70	0.75	0.72	0.72	0.59	0.56	1.00	1.00	0.75	0.50	1.00	0.70	0.75	0.95	0.92	0.75
9318 (COPS2)	1.00	0.74	0.51	0.58	0.59	1.00	0.58	1.00	0.51	0.70	0.64	1.00	0.55	0.52	1.00	0.61	0.64	0.62	0.56	0.50	0.52	0.50	0.18	0.18	0.70	0.37	0.64	0.52	0.52	0.74	0.54	0.70	0.75	0.72	0.72	0.58	0.46	0.18	1.00	0.75	0.50	0.59	0.70	0.75	0.50	0.59	0.75
2873 (GPS1)	1.00	0.73	0.50	0.57	0.58	0.58	1.00	1.00	0.38	0.69	0.63	1.00	0.55	0.51	1.00	0.64	0.63	0.61	0.56	0.49	0.51	0.50	0.18	0.18	0.69	0.37	0.63	0.52	0.51	0.73	0.53	0.69	0.74	0.71	0.71	0.57	0.46	0.18	1.00	0.74	0.50	0.58	0.68	0.74	0.49	0.59	0.74
50813 (COPS7A)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.18	0.18	1.00	0.82	0.82	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.18	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00
10987 (COPS5)	1.00	0.51	0.40	0.46	0.42	0.51	0.38	1.00	1.00	0.44	0.45	1.00	0.43	0.41	1.00	0.51	0.43	0.50	0.46	0.39	0.42	0.44	0.24	0.24	0.44	0.32	0.42	0.49	0.41	0.49	0.50	0.44	0.46	0.55	0.55	0.71	0.37	0.24	1.00	0.46	0.43	0.42	0.48	0.52	0.39	0.44	0.46
8405 (SPOP)	1.00	0.81	0.59	0.64	0.70	0.70	0.69	1.00	0.44	1.00	0.87	1.00	0.62	0.72	1.00	0.73	0.74	0.67	0.71	0.59	0.58	0.63	0.18	0.18	1.00	0.43	0.71	0.58	0.72	0.82	0.63	1.00	0.85	0.76	0.76	0.68	0.52	0.18	1.00	0.85	0.55	0.70	0.77	0.82	0.59	0.68	0.85
4738 (NEDD8)	1.00	0.74	0.57	0.61	0.64	0.64	0.63	1.00	0.45	0.87	1.00	1.00	0.60	0.68	1.00	0.70	0.70	0.64	0.68	0.56	0.56	0.62	0.23	0.23	0.87	0.42	0.64	0.56	0.68	0.74	0.59	0.87	0.75	0.77	0.77	0.62	0.51	0.23	1.00	0.75	0.54	0.64	0.78	0.75	0.56	0.63	0.75
55832 (CAND1)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.18	0.18	1.00	0.82	0.82	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.18	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00
6502 (SKP2)	1.00	0.67	0.90	0.76	0.93	0.55	0.55	1.00	0.43	0.62	0.60	1.00	1.00	0.87	1.00	0.80	0.60	0.93	0.88	0.76	0.83	0.89	1.00	1.00	0.62	0.90	0.57	0.88	0.87	0.72	0.55	0.62	0.72	0.68	0.68	0.55	0.55	1.00	1.00	0.66	0.50	0.93	0.64	0.73	0.91	0.88	0.66
7322 (UBE2D2)	1.00	0.64	0.87	0.70	0.90	0.52	0.51	1.00	0.41	0.72	0.68	1.00	0.87	1.00	1.00	0.81	0.56	0.86	0.89	0.74	0.73	0.88	1.00	1.00	0.72	0.79	0.55	0.81	1.00	0.63	0.52	0.72	0.62	0.65	0.65	0.52	0.53	1.00	1.00	0.62	0.48	0.90	0.61	0.66	0.94	0.85	0.62
10980 (COPS6)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.18	0.18	1.00	0.82	0.82	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.18	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00
55294 (FBXW7)	1.00	0.69	0.76	0.71	0.76	0.61	0.64	1.00	0.51	0.73	0.70	1.00	0.80	0.81	1.00	1.00	0.64	0.77	0.80	0.70	0.70	0.80	1.00	1.00	0.73	0.67	0.59	0.74	0.81	0.70	0.60	0.73	0.71	0.70	0.70	0.62	0.59	1.00	1.00	0.67	0.56	0.76	0.67	0.71	0.76	0.75	0.67
26249 (KLHL3)	1.00	0.76	0.56	0.61	0.64	0.64	0.63	1.00	0.43	0.74	0.70	1.00	0.60	0.56	1.00	0.64	1.00	0.65	0.59	0.55	0.56	0.54	0.23	0.23	0.74	0.41	0.67	0.56	0.56	0.77	0.58	0.74	0.79	0.79	0.79	0.63	0.50	0.23	1.00	0.79	0.54	0.64	0.82	0.78	0.55	0.64	0.79
6500 (SKP1)	1.00	0.74	0.88	0.74	0.90	0.62	0.61	1.00	0.50	0.67	0.64	1.00	0.93	0.86	1.00	0.77	0.65	1.00	0.88	0.77	0.86	0.90	1.00	1.00	0.67	0.90	0.65	0.91	0.86	0.70	0.61	0.67	0.70	0.74	0.74	0.62	0.60	1.00	1.00	0.70	0.55	0.90	0.69	0.75	0.89	0.87	0.70
8452 (CUL3)	1.00	0.65	0.83	0.70	0.84	0.56	0.56	1.00	0.46	0.71	0.68	1.00	0.88	0.89	1.00	0.80	0.59	0.88	1.00	0.72	0.78	0.90	1.00	1.00	0.71	0.81	0.55	0.83	0.89	0.65	0.56	0.71	0.64	0.66	0.66	0.56	0.56	1.00	1.00	0.64	0.51	0.84	0.63	0.66	0.84	0.82	0.64
140739 (UBE2F)	1.00	0.65	0.91	0.81	0.79	0.50	0.49	1.00	0.39	0.59	0.56	1.00	0.76	0.74	1.00	0.70	0.55	0.77	0.72	1.00	0.81	0.79	0.70	0.70	0.59	0.66	0.55	0.70	0.74	0.64	0.50	0.59	0.63	0.66	0.66	0.50	0.52	0.70	1.00	0.63	0.47	0.79	0.61	0.66	0.77	0.76	0.63
9616 (RNF7)	1.00	0.67	0.83	0.74	0.77	0.52	0.51	1.00	0.42	0.58	0.56	1.00	0.83	0.73	1.00	0.70	0.56	0.86	0.78	0.81	1.00	0.88	0.77	0.77	0.58	0.83	0.59	0.78	0.73	0.62	0.52	0.58	0.61	0.68	0.68	0.52	0.53	0.77	1.00	0.61	0.56	0.77	0.60	0.68	0.75	0.75	0.61
9978 (RBX1)	1.00	0.62	0.88	0.75	0.84	0.50	0.50	1.00	0.44	0.63	0.62	1.00	0.89	0.88	1.00	0.80	0.54	0.90	0.90	0.79	0.88	1.00	1.00	1.00	0.63	0.89	0.54	0.84	0.88	0.58	0.51	0.63	0.57	0.65	0.65	0.51	0.53	1.00	1.00	0.57	0.51	0.84	0.58	0.63	0.83	0.82	0.61
55958 (KLHL9)	0.18	0.18	1.00	0.70	1.00	0.18	0.18	0.18	0.24	0.18	0.23	0.18	1.00	1.00	0.18	1.00	0.23	1.00	1.00	0.70	0.77	1.00	1.00	1.00	0.18	1.00	0.15	1.00	1.00	0.18	0.24	0.18	0.18	0.32	0.32	0.19	0.32	1.00	0.18	0.18	0.18	1.00	0.32	0.18	1.00	1.00	0.18
90293 (KLHL13)	0.18	0.18	1.00	0.70	1.00	0.18	0.18	0.18	0.24	0.18	0.23	0.18	1.00	1.00	0.18	1.00	0.23	1.00	1.00	0.70	0.77	1.00	1.00	1.00	0.18	1.00	0.15	1.00	1.00	0.18	0.24	0.18	0.18	0.32	0.32	0.19	0.32	1.00	0.18	0.18	0.18	1.00	0.32	0.18	1.00	1.00	0.18
6923 (TCEB2)	1.00	0.81	0.59	0.64	0.70	0.70	0.69	1.00	0.44	1.00	0.87	1.00	0.62	0.72	1.00	0.73	0.74	0.67	0.71	0.59	0.58	0.63	0.18	0.18	1.00	0.43	0.71	0.58	0.72	0.82	0.63	1.00	0.85	0.76	0.76	0.68	0.52	0.18	1.00	0.85	0.55	0.70	0.77	0.82	0.59	0.68	0.85
51529 (ANAPC11)	0.82	0.55	0.83	0.61	0.85	0.37	0.37	0.82	0.32	0.43	0.42	0.82	0.90	0.79	0.82	0.67	0.41	0.90	0.81	0.66	0.83	0.89	1.00	1.00	0.43	1.00	0.50	0.83	0.79	0.47	0.39	0.43	0.46	0.57	0.57	0.38	0.43	1.00	0.82	0.46	0.36	0.85	0.47	0.56	0.84	0.80	0.46
55208 (DCUN1D2)	0.82	0.97	0.56	0.57	0.64	0.64	0.63	0.82	0.42	0.71	0.64	0.82	0.57	0.55	0.82	0.59	0.67	0.65	0.55	0.55	0.59	0.54	0.15	0.15	0.71	0.50	1.00	0.53	0.55	0.71	0.58	0.71	0.74	0.90	0.90	0.63	0.49	0.15	0.82	0.74	0.49	0.64	0.69	0.78	0.55	0.61	0.74
8945 (BTRC)	1.00	0.63	0.83	0.68	0.85	0.52	0.52	1.00	0.49	0.58	0.56	1.00	0.88	0.81	1.00	0.74	0.56	0.91	0.83	0.70	0.78	0.84	1.00	1.00	0.58	0.83	0.53	1.00	0.81	0.62	0.65	0.58	0.61	0.64	0.64	0.52	0.53	1.00	1.00	0.61	0.53	0.85	0.60	0.64	0.84	0.81	0.61
7321 (UBE2D1)	1.00	0.64	0.87	0.70	0.90	0.52	0.51	1.00	0.41	0.72	0.68	1.00	0.87	1.00	1.00	0.81	0.56	0.86	0.89	0.74	0.73	0.88	1.00	1.00	0.72	0.79	0.55	0.81	1.00	0.63	0.52	0.72	0.62	0.65	0.65	0.52	0.53	1.00	1.00	0.62	0.48	0.90	0.61	0.66	0.94	0.85	0.62
11275 (KLHL2)	1.00	0.82	0.64	0.72	0.74	0.74	0.73	1.00	0.49	0.82	0.74	1.00	0.72	0.63	1.00	0.70	0.77	0.70	0.65	0.64	0.62	0.58	0.18	0.18	0.82	0.47	0.71	0.62	0.63	1.00	0.67	0.82	0.94	0.78	0.78	0.73	0.57	0.18	1.00	0.86	0.59	0.74	0.80	0.89	0.64	0.72	0.86
7317 (UBA1)	1.00	0.68	0.51	0.70	0.57	0.54	0.53	1.00	0.50	0.63	0.59	1.00	0.55	0.52	1.00	0.60	0.58	0.61	0.56	0.50	0.52	0.51	0.24	0.24	0.63	0.39	0.58	0.65	0.52	0.67	1.00	0.63	0.67	0.67	0.67	0.54	0.46	0.24	1.00	0.67	0.55	0.57	0.63	0.69	0.50	0.57	0.67
339745 (SPOPL)	1.00	0.81	0.59	0.64	0.70	0.70	0.69	1.00	0.44	1.00	0.87	1.00	0.62	0.72	1.00	0.73	0.74	0.67	0.71	0.59	0.58	0.63	0.18	0.18	1.00	0.43	0.71	0.58	0.72	0.82	0.63	1.00	0.85	0.76	0.76	0.68	0.52	0.18	1.00	0.85	0.55	0.70	0.77	0.82	0.59	0.68	0.85
59349 (KLHL12)	1.00	0.84	0.64	0.72	0.75	0.75	0.74	1.00	0.46	0.85	0.75	1.00	0.72	0.62	1.00	0.71	0.79	0.70	0.64	0.63	0.61	0.57	0.18	0.18	0.85	0.46	0.74	0.61	0.62	0.94	0.67	0.85	1.00	0.79	0.79	0.74	0.55	0.18	1.00	0.91	0.57	0.75	0.82	0.92	0.63	0.72	0.91
123879 (DCUN1D3)	1.00	0.94	0.67	0.68	0.72	0.72	0.71	1.00	0.55	0.76	0.77	1.00	0.68	0.65	1.00	0.70	0.79	0.74	0.66	0.66	0.68	0.65	0.32	0.32	0.76	0.57	0.90	0.64	0.65	0.78	0.67	0.76	0.79	1.00	1.00	0.71	0.60	0.32	1.00	0.79	0.62	0.72	0.89	0.82	0.66	0.70	0.79
84259 (DCUN1D5)	1.00	0.94	0.67	0.68	0.72	0.72	0.71	1.00	0.55	0.76	0.77	1.00	0.68	0.65	1.00	0.70	0.79	0.74	0.66	0.66	0.68	0.65	0.32	0.32	0.76	0.57	0.90	0.64	0.65	0.78	0.67	0.76	0.79	1.00	1.00	0.71	0.60	0.32	1.00	0.79	0.62	0.72	0.89	0.82	0.66	0.70	0.79
51138 (COPS4)	1.00	0.73	0.51	0.58	0.59	0.58	0.57	1.00	0.71	0.68	0.62	1.00	0.55	0.52	1.00	0.62	0.63	0.62	0.56	0.50	0.52	0.51	0.19	0.19	0.68	0.38	0.63	0.52	0.52	0.73	0.54	0.68	0.74	0.71	0.71	1.00	0.46	0.19	1.00	0.74	0.50	0.59	0.68	0.74	0.50	0.59	0.74
9212 (AURKB)	1.00	0.59	0.53	0.56	0.56	0.46	0.46	1.00	0.37	0.52	0.51	1.00	0.55	0.53	1.00	0.59	0.50	0.60	0.56	0.52	0.53	0.53	0.32	0.32	0.52	0.43	0.49	0.53	0.53	0.57	0.46	0.52	0.55	0.60	0.60	0.46	1.00	0.32	1.00	0.55	0.45	0.56	0.54	0.60	0.52	0.57	0.55
9903 (KLHL21)	0.18	0.18	1.00	0.70	1.00	0.18	0.18	0.18	0.24	0.18	0.23	0.18	1.00	1.00	0.18	1.00	0.23	1.00	1.00	0.70	0.77	1.00	1.00	1.00	0.18	1.00	0.15	1.00	1.00	0.18	0.24	0.18	0.18	0.32	0.32	0.19	0.32	1.00	0.18	0.18	0.18	1.00	0.32	0.18	1.00	1.00	0.18
9820 (CUL7)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.18	0.18	1.00	0.82	0.82	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.18	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00
84861 (KLHL22)	1.00	0.84	0.64	0.67	0.75	0.75	0.74	1.00	0.46	0.85	0.75	1.00	0.66	0.62	1.00	0.67	0.79	0.70	0.64	0.63	0.61	0.57	0.18	0.18	0.85	0.46	0.74	0.61	0.62	0.86	0.67	0.85	0.91	0.79	0.79	0.74	0.55	0.18	1.00	1.00	0.57	0.75	0.82	0.86	0.63	0.72	0.91
2736 (GLI2)	1.00	0.60	0.47	0.52	0.50	0.50	0.50	1.00	0.43	0.55	0.54	1.00	0.50	0.48	1.00	0.56	0.54	0.55	0.51	0.47	0.56	0.51	0.18	0.18	0.55	0.36	0.49	0.53	0.48	0.59	0.55	0.55	0.57	0.62	0.62	0.50	0.45	0.18	1.00	0.57	1.00	0.50	0.58	0.61	0.47	0.51	0.61
57542 (KLHL42)	1.00	0.74	0.94	0.74	1.00	0.59	0.58	1.00	0.42	0.70	0.64	1.00	0.93	0.90	1.00	0.76	0.64	0.90	0.84	0.79	0.77	0.84	1.00	1.00	0.70	0.85	0.64	0.85	0.90	0.74	0.57	0.70	0.75	0.72	0.72	0.59	0.56	1.00	1.00	0.75	0.50	1.00	0.70	0.75	0.95	0.92	0.75
8139 (GAN)	1.00	0.79	0.63	0.66	0.70	0.70	0.68	1.00	0.48	0.77	0.78	1.00	0.64	0.61	1.00	0.67	0.82	0.69	0.63	0.61	0.60	0.58	0.32	0.32	0.77	0.47	0.69	0.60	0.61	0.80	0.63	0.77	0.82	0.89	0.89	0.68	0.54	0.32	1.00	0.82	0.58	0.70	1.00	0.80	0.61	0.68	0.82
200845 (KCTD6)	1.00	0.87	0.67	0.73	0.75	0.75	0.74	1.00	0.52	0.82	0.75	1.00	0.73	0.66	1.00	0.71	0.78	0.75	0.66	0.66	0.68	0.63	0.18	0.18	0.82	0.56	0.78	0.64	0.66	0.89	0.69	0.82	0.92	0.82	0.82	0.74	0.60	0.18	1.00	0.86	0.61	0.75	0.80	1.00	0.66	0.73	0.86
997 (CDC34)	1.00	0.65	0.91	0.71	0.95	0.50	0.49	1.00	0.39	0.59	0.56	1.00	0.91	0.94	1.00	0.76	0.55	0.89	0.84	0.77	0.75	0.83	1.00	1.00	0.59	0.84	0.55	0.84	0.94	0.64	0.50	0.59	0.63	0.66	0.66	0.50	0.52	1.00	1.00	0.63	0.47	0.95	0.61	0.66	1.00	0.90	0.63
27252 (KLHL20)	1.00	0.72	0.88	0.72	0.92	0.59	0.59	1.00	0.44	0.68	0.63	1.00	0.88	0.85	1.00	0.75	0.64	0.87	0.82	0.76	0.75	0.82	1.00	1.00	0.68	0.80	0.61	0.81	0.85	0.72	0.57	0.68	0.72	0.70	0.70	0.59	0.57	1.00	1.00	0.72	0.51	0.92	0.68	0.73	0.90	1.00	0.72
9817 (KEAP1)	1.00	0.84	0.64	0.67	0.75	0.75	0.74	1.00	0.46	0.85	0.75	1.00	0.66	0.62	1.00	0.67	0.79	0.70	0.64	0.63	0.61	0.61	0.18	0.18	0.85	0.46	0.74	0.61	0.62	0.86	0.67	0.85	0.91	0.79	0.79	0.74	0.55	0.18	1.00	0.91	0.61	0.75	0.82	0.86	0.63	0.72	1.00

Association with High Altitude

Protein Official symbol	Source Organism	Tissue of Expression	Level of hypoxia	Altitude	Duration of experiment	Level of expression	Fold change	Experiment details	geographical location	ethnicity of the patients	Control group	Control (Fold change)	Reference (PMID)
CUL3	Human	Blood	-	3650 m	48 hours	downregulated	0.66	Microarray	Himalayas	Indians	1	HAPE Pateints Vs Normal	http://medind.nic.in/iab/t12/i1/iabt12i1p1.pdf

Association with TF

TF	TF Entrez	Gene	Gene Entrez	Type	PMID	Database

Association with miRNA

miRTarBase ID	miRNA	Species (miRNA)	Protein Official Symbol	Human Entrez ID	Species (Target Gene)	Experiments	Support Type	References (PMID)
MIRT004141	hsa-miR-192-5p	Homo sapiens	CUL3	8452	Homo sapiens	Microarray	Functional MTI (Weak)	16822819
MIRT032239	hsa-let-7b-5p	Homo sapiens	CUL3	8452	Homo sapiens	Proteomics	Functional MTI (Weak)	18668040
MIRT040752	hsa-miR-18a-3p	Homo sapiens	CUL3	8452	Homo sapiens	CLASH	Functional MTI (Weak)	23622248
MIRT047577	hsa-miR-10a-5p	Homo sapiens	CUL3	8452	Homo sapiens	CLASH	Functional MTI (Weak)	23622248
MIRT048703	hsa-miR-99a-5p	Homo sapiens	CUL3	8452	Homo sapiens	CLASH	Functional MTI (Weak)	23622248
MIRT440856	hsa-miR-218-5p	Homo sapiens	CUL3	8452	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23212916
MIRT447617	hsa-miR-1266-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22100165
MIRT447623	hsa-miR-3177-5p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22100165
MIRT447626	hsa-miR-511-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22100165
MIRT447615	hsa-miR-4477a	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22100165
MIRT447618	hsa-miR-4668-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22100165
MIRT447622	hsa-miR-4764-5p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22100165
MIRT447619	hsa-miR-3613-5p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22100165
MIRT447621	hsa-miR-6807-5p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22100165
MIRT447614	hsa-miR-203a-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22100165
MIRT447625	hsa-miR-1225-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22100165
MIRT447616	hsa-miR-4635	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22100165
MIRT447620	hsa-miR-591	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22100165
MIRT447624	hsa-miR-1233-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22100165
MIRT447627	hsa-miR-1265	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22100165
MIRT538251	hsa-miR-3529-5p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538259	hsa-miR-302d-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538260	hsa-miR-302a-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT538262	hsa-miR-520c-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538248	hsa-miR-4536-5p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT538251	hsa-miR-3529-5p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT538253	hsa-miR-5197-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT538253	hsa-miR-5197-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538258	hsa-miR-520e	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT538261	hsa-miR-302b-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538252	hsa-miR-4650-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538250	hsa-miR-379-5p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT538260	hsa-miR-302a-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538258	hsa-miR-520e	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538268	hsa-miR-302c-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538269	hsa-miR-520a-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT538275	hsa-miR-301a-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538265	hsa-miR-373-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT538267	hsa-miR-302e	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT538269	hsa-miR-520a-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538272	hsa-miR-130a-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT538273	hsa-miR-130b-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT538254	hsa-miR-3120-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538252	hsa-miR-4650-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT538263	hsa-miR-520d-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538256	hsa-miR-519b-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT538266	hsa-miR-372-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT538276	hsa-miR-301b-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT538270	hsa-miR-454-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538271	hsa-miR-4295	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT538276	hsa-miR-301b-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538248	hsa-miR-4536-5p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538257	hsa-miR-519a-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538249	hsa-miR-4451	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT538261	hsa-miR-302b-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT538256	hsa-miR-519b-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538270	hsa-miR-454-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT538274	hsa-miR-3666	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT538265	hsa-miR-373-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538268	hsa-miR-302c-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT538271	hsa-miR-4295	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538273	hsa-miR-130b-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538275	hsa-miR-301a-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT538266	hsa-miR-372-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538274	hsa-miR-3666	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538264	hsa-miR-520b	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538254	hsa-miR-3120-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT538255	hsa-miR-519c-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT538249	hsa-miR-4451	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538250	hsa-miR-379-5p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538255	hsa-miR-519c-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538257	hsa-miR-519a-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT538259	hsa-miR-302d-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT538262	hsa-miR-520c-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT538263	hsa-miR-520d-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT538264	hsa-miR-520b	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT538272	hsa-miR-130a-3p	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538267	hsa-miR-302e	Homo sapiens	CUL3	8452	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT659247	hsa-miR-4524b-5p	Homo sapiens	CUL3	8452	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT659249	hsa-miR-6734-3p	Homo sapiens	CUL3	8452	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT659259	hsa-miR-15b-5p	Homo sapiens	CUL3	8452	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT659254	hsa-miR-503-5p	Homo sapiens	CUL3	8452	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT659250	hsa-miR-4705	Homo sapiens	CUL3	8452	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT659260	hsa-miR-15a-5p	Homo sapiens	CUL3	8452	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT659253	hsa-miR-6838-5p	Homo sapiens	CUL3	8452	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT659257	hsa-miR-195-5p	Homo sapiens	CUL3	8452	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT659251	hsa-miR-339-5p	Homo sapiens	CUL3	8452	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT659256	hsa-miR-424-5p	Homo sapiens	CUL3	8452	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT659258	hsa-miR-16-5p	Homo sapiens	CUL3	8452	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT659252	hsa-miR-646	Homo sapiens	CUL3	8452	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT659255	hsa-miR-497-5p	Homo sapiens	CUL3	8452	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT659248	hsa-miR-4524a-5p	Homo sapiens	CUL3	8452	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT659246	hsa-miR-670-5p	Homo sapiens	CUL3	8452	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327

Gene Ontology

ID	GO ID	GO Term	GO Type
8452	GO:0017145	stem cell division	GOTERM_BP_DIRECT
8452	GO:0035024	negative regulation of Rho protein signal transduction	GOTERM_BP_DIRECT
8452	GO:0045842	positive regulation of mitotic metaphase/anaphase transition	GOTERM_BP_DIRECT
8452	GO:0005794	Golgi apparatus	GOTERM_CC_DIRECT
8452	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation	GOTERM_BP_DIRECT
8452	GO:0032467	positive regulation of cytokinesis	GOTERM_BP_DIRECT
8452	GO:0072576	liver morphogenesis	GOTERM_BP_DIRECT
8452	GO:0090090	negative regulation of canonical Wnt signaling pathway	GOTERM_BP_DIRECT
8452	GO:0031208	heat shock protein binding	GOTERM_MF_DIRECT
8452	GO:0061630	ubiquitin protein ligase activity	GOTERM_MF_DIRECT
8452	GO:0000139	Golgi membrane	GOTERM_CC_DIRECT
8452	GO:0031461	cullin-RING ubiquitin ligase complex	GOTERM_CC_DIRECT
8452	GO:0000165	MAPK cascade	GOTERM_BP_DIRECT
8452	GO:0006513	protein monoubiquitination	GOTERM_BP_DIRECT
8452	GO:0007080	mitotic metaphase plate congression	GOTERM_BP_DIRECT
8452	GO:0007369	gastrulation	GOTERM_BP_DIRECT
8452	GO:0005654	nucleoplasm	GOTERM_CC_DIRECT
8452	GO:0000278	mitotic cell cycle	GOTERM_BP_DIRECT
8452	GO:0007229	integrin-mediated signaling pathway	GOTERM_BP_DIRECT
8452	GO:0008284	positive regulation of cell proliferation	GOTERM_BP_DIRECT
8452	GO:0016567	protein ubiquitination	GOTERM_BP_DIRECT
8452	GO:0016020	membrane	GOTERM_CC_DIRECT
8452	GO:0000122	negative regulation of transcription from RNA polymerase II promoter	GOTERM_BP_DIRECT
8452	GO:0007050	cell cycle arrest	GOTERM_BP_DIRECT
8452	GO:0016477	cell migration	GOTERM_BP_DIRECT
8452	GO:0030030	cell projection organization	GOTERM_BP_DIRECT
8452	GO:0005634	nucleus	GOTERM_CC_DIRECT
8452	GO:0070062	extracellular exosome	GOTERM_CC_DIRECT
8452	GO:0031145	anaphase-promoting complex-dependent catabolic process	GOTERM_BP_DIRECT
8452	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	GOTERM_BP_DIRECT
8452	GO:0048208	COPII vesicle coating	GOTERM_BP_DIRECT
8452	GO:0031625	ubiquitin protein ligase binding	GOTERM_MF_DIRECT
8452	GO:0040016	embryonic cleavage	GOTERM_BP_DIRECT
8452	GO:0097193	intrinsic apoptotic signaling pathway	GOTERM_BP_DIRECT
8452	GO:0030332	protein kinase activator activity	GOTERM_MF_DIRECT
8452	GO:0000209	protein polyubiquitination	GOTERM_BP_DIRECT
8452	GO:0004842	ubiquitin-protein transferase activity	GOTERM_MF_DIRECT
8452	GO:0005829	cytosol	GOTERM_CC_DIRECT
8452	GO:0000082	G1/S transition of mitotic cell cycle	GOTERM_BP_DIRECT
8452	GO:0042803	protein homodimerization activity	GOTERM_MF_DIRECT
8452	GO:0006888	ER to Golgi vesicle-mediated transport	GOTERM_BP_DIRECT
8452	GO:0043149	stress fiber assembly	GOTERM_BP_DIRECT
8452	GO:0005515	protein binding	GOTERM_MF_DIRECT
8452	GO:0046982	protein heterodimerization activity	GOTERM_MF_DIRECT
8452	GO:0031463	Cul3-RING ubiquitin ligase complex	GOTERM_CC_DIRECT
8452	GO:0006511	ubiquitin-dependent protein catabolic process	GOTERM_BP_DIRECT
8452	GO:0016055	Wnt signaling pathway	GOTERM_BP_DIRECT
8452	GO:0001831	trophectodermal cellular morphogenesis	GOTERM_BP_DIRECT
8452	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	GOTERM_BP_DIRECT
8452	GO:0044346	fibroblast apoptotic process	GOTERM_BP_DIRECT
8452	GO:0005827	polar microtubule	GOTERM_CC_DIRECT

Pathways

Human Entrez ID	KEGG ID	KEGG Term
8452	hsa04120	Ubiquitin mediated proteolysis

Association with Disease

Protein Official Symbol	Human Entrez ID	Disease Name	Disease Id	Disease Semantic Type	Semantic score	DSI	DPI	Disease Type
CUL3	8452	Prostatic Neoplasms	C0033578	Neoplastic Process	0.3	0.639	0.483	group
CUL3	8452	Neurodevelopmental Disorders	C1535926	Mental or Behavioral Dysfunction	0.3	0.639	0.483	group
CUL3	8452	melanoma	C0025202	Neoplastic Process	0.3	0.639	0.483	disease
CUL3	8452	Malignant neoplasm of prostate	C0376358	Neoplastic Process	0.3	0.639	0.483	disease
CUL3	8452	PSEUDOHYPOALDOSTERONISM, TYPE IIE	C3469606	Disease or Syndrome	0.71	0.639	0.483	disease
CUL3	8452	Intellectual Disability	C3714756	Mental or Behavioral Dysfunction	0.3	0.639	0.483	group

Association with Drug

Protein Official Symbol	Human Entrez ID	drug_claim_primary_name	drug_name	drug_chembl_id	interaction_types