ALTITUDEOMICSDB

Heparanase

AltitudeomicsDB

Protein Official symbol	HPSE
Aliases	HPSE HEP HPA HPA1 HPR1 HPSE1 HSE1
Chromosomal Location	4
Length	543
Uniprot ID	Q9Y251
EC number	3.2.1.166
Protein family Information(Pfam)	PF03662;
PDB id	5E8M;5E97;5E98;5E9B;5E9C;5L9Y;5L9Z;5LA4;5LA7;
InterPro ID	IPR005199;IPR017853;
dbSNP	rs11099592

Protein Protein Interaction

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AltitudeomicsDB

Protein 1	Protein 2	Combine Score
ELANE	DEFA4	0.987
ELANE	SLPI	0.982
HSPG2	GPC1	0.981
DEFA4	CAMP	0.98
SDC1	GPC1	0.98
GPC4	SDC2	0.978
GPC6	SDC2	0.978
HSPG2	GPC2	0.977
GPC6	HSPG2	0.976
SDC2	GPC2	0.976
SDC1	HSPG2	0.975
HSPG2	GPC4	0.975
SDC2	GPC1	0.974
TIMP2	MMP8	0.974
LCN2	SLPI	0.974
SDC4	GPC1	0.973
HSPG2	SDC2	0.973
GPC5	HSPG2	0.971
AGRN	GPC1	0.971
SDC3	GPC1	0.971
SDC1	GPC4	0.969
ELANE	CAMP	0.969
HSPG2	SDC4	0.969
SDC1	GPC6	0.969
SDC1	GPC2	0.968
ELANE	MMP8	0.967
AGRN	GPC2	0.967
AGRN	GPC4	0.967
GPC3	HSPG2	0.967
SDC3	GPC2	0.967
GPC5	SDC2	0.967
GPC4	SDC3	0.967
SDC1	GPC5	0.967
AGRN	GPC5	0.966
AGRN	GPC6	0.966
GPC6	SDC3	0.966
GPC3	SDC1	0.965
GPC5	SDC3	0.965
GPC3	SDC2	0.965
SLPI	CAMP	0.964
CTSD	CTSZ	0.964
CHIT1	LYZ	0.963
SDC4	GPC4	0.963
HSPG2	SDC3	0.963
GPC6	SDC4	0.963
SDC4	GPC2	0.962
CXCL1	LCN2	0.959
DEFA4	MMP8	0.959
LCN2	CAMP	0.958
SDC1	AGRN	0.958
GPC3	AGRN	0.958
GPC3	SDC3	0.958
GPC5	SDC4	0.957
HP	LRG1	0.956
GPC3	SDC4	0.955
B2M	LCN2	0.955
TCN1	MMP8	0.955
LCN2	TIMP2	0.954
CNN2	VCL	0.954
AGRN	SDC2	0.954
HPSE	HSPG2	0.953
LCN2	HP	0.951
HPSE	SDC1	0.951
ELANE	HP	0.95
ARG1	MMP8	0.95
LCN2	MMP8	0.948
AGRN	HSPG2	0.947
B2M	HP	0.946
B2M	LYZ	0.946
ELANE	LCN2	0.946
LCN2	TCN1	0.946
AGRN	SDC4	0.945
AGRN	SDC3	0.945
CXCL1	ARG1	0.943
PTPN6	ARG1	0.942
ELANE	CXCL1	0.942
CXCL1	MMP8	0.941
CYFIP1	HP	0.941
CXCL1	CAMP	0.941
LCN2	DEFA4	0.941
SLPI	LYZ	0.939
ELANE	CTSD	0.939
HPSE	GPC1	0.938
CXCL1	NFKB1	0.938
CXCL1	PTX3	0.938
CXCL1	TIMP2	0.938
CHIT1	ARG1	0.938
GPC3	GPC4	0.937
DEFA4	TCN1	0.935
CHIT1	CNN2	0.935
LYZ	MMP8	0.935
CXCL1	SLPI	0.935
ELANE	LYZ	0.934
FOLR3	DEFA4	0.934
FOLR3	TCN1	0.933
CAMP	MMP8	0.933
FRK	VCL	0.932
ARG1	HP	0.932
CAMP	LYZ	0.931
DEFA4	LYZ	0.931
LCN2	LYZ	0.931
B2M	CXCL1	0.931
TIMP2	CTSD	0.93
LCN2	PTX3	0.929
PTX3	CFP	0.929
SDC1	SDC4	0.929
GPC3	GPC6	0.928
ELANE	TIMP2	0.928
ELANE	ARG1	0.928
HPSE	SDC2	0.928
LCN2	LRG1	0.927
GPC3	GPC2	0.927
SDC1	SDC2	0.926
LYZ	CFP	0.926
GPC5	GPC2	0.926
HPSE	SDC4	0.925
SLPI	MMP8	0.925
HP	MMP8	0.925
B2M	NFKB1	0.924
SDC3	SDC2	0.924
SDC4	SDC3	0.924
GPC3	GPC1	0.924
FOLR3	OSCAR	0.924
HPSE	IDS	0.923
LCN2	CTSD	0.923
PTPN6	NFKB1	0.923
HP	PTX3	0.923
CAMP	PTX3	0.923
HPSE	GPC3	0.923
LCN2	ARG1	0.923
HPSE	AGRN	0.923
HP	CTSD	0.922
SDC1	SDC3	0.922
ELANE	TCN1	0.922
ACAA1	NFKB1	0.922
CXCL1	HP	0.922
HP	CAMP	0.922
CHIT1	CTSD	0.922
HPSE	GPC2	0.922
HPSE	GPC6	0.922
ELANE	CFP	0.922
GPC5	GPC6	0.922
HPSE	GPC4	0.921
B2M	CTSD	0.921
HP	LYZ	0.921
PTX3	MMP8	0.921
ELANE	PTX3	0.921
B2M	SLPI	0.921
HPSE	GPC5	0.92
PTPN6	DOCK2	0.92
GPC5	GPC4	0.92
B2M	HSPG2	0.92
ARG1	LYZ	0.919
CAMP	CFP	0.919
B2M	TIMP2	0.919
GPC5	GPC1	0.919
CXCL1	LYZ	0.919
HP	CFP	0.919
MMP8	CTSD	0.918
HP	SLPI	0.918
SLPI	LRG1	0.918
PTPN6	GHDC	0.918
TIMP2	CTSZ	0.918
SDC4	SDC2	0.917
MMP8	VCL	0.917
B2M	CAMP	0.917
B2M	LRG1	0.917
LYZ	CTSD	0.917
ARG1	CAMP	0.917
CYFIP1	TCN1	0.917
HPSE	HP	0.917
LYZ	DOCK2	0.917
ARG1	ACAA1	0.916
SLPI	DEFA4	0.916
B2M	CTSZ	0.916
LYZ	NFKB1	0.916
ELANE	B2M	0.916
KPNB1	NFKB1	0.916
LCN2	NFKB1	0.915
B2M	ARG1	0.915
CAMP	CTSD	0.915
B2M	VCL	0.915
SLPI	CTSD	0.915
ARG1	DEFA4	0.914
CHIT1	CAMP	0.914
QSOX1	LRG1	0.914
QSOX1	CTSD	0.914
CHIT1	SLPI	0.914
PTX3	TIMP2	0.914
HPSE	SDC3	0.914
HPSE	TIMP2	0.913
PTPN6	LYZ	0.913
CTSD	VCL	0.913
KPNB1	TCN1	0.913
SLPI	TCN1	0.913
PTX3	CTSZ	0.913
TIMP2	VCL	0.913
HPSE	VCL	0.912
HP	NFKB1	0.912
FOLR3	MMP8	0.912
B2M	PTPN6	0.912
SLPI	CFP	0.912
QSOX1	TIMP2	0.912
LCN2	CHIT1	0.912
FOLR3	CAMP	0.912
AOC1	LCN2	0.911
AOC1	HP	0.911
B2M	DOCK2	0.911
LRG1	PTX3	0.91
OSCAR	LYZ	0.91
HPSE	LYZ	0.91
HP	TIMP2	0.91
OSCAR	CFP	0.91
LRG1	LYZ	0.91
GSDMD	CAMP	0.91
GSDMD	PTPN6	0.91
B2M	CFP	0.91
ARG1	NFKB1	0.909
HPSE	TCN1	0.909
AOC1	ACAA1	0.909
LRG1	DEFA4	0.909
AOC1	LYZ	0.909
OSCAR	DOCK2	0.909
MMP8	CTSZ	0.908
FOLR3	LYZ	0.908
NFKB1	VCL	0.908
CXCL1	CTSD	0.908
HPSE	MMP8	0.908
SLPI	TIMP2	0.908
TIMP2	NFKB1	0.908
ARG1	PTX3	0.908
CTSD	NFKB1	0.908
GPC4	GPC1	0.908
HPSE	KPNB1	0.908
DOCK2	CTSZ	0.908
DOCK2	CFP	0.908
CXCL1	QSOX1	0.908
DEFA4	CFP	0.908
DOCK2	NFKB1	0.908
GPC6	GPC4	0.908
CXCL1	CTSZ	0.908
GSDMD	LYZ	0.907
GHDC	CTSZ	0.907
B2M	MMP8	0.907
LYZ	CTSZ	0.907
CNN2	DOCK2	0.907
FRK	DOCK2	0.907
CYFIP1	VCL	0.907
FOLR3	ELANE	0.907
CFP	CTSD	0.907
OSCAR	PTPN6	0.907
OSCAR	CTSZ	0.907
FOLR3	CFP	0.907
CXCL1	VCL	0.907
PTPN6	CTSZ	0.907
FRK	PTPN6	0.907
CXCL1	CFP	0.907
GPC6	GPC1	0.907
ARG1	TCN1	0.907
ARG1	CFP	0.907
CAMP	TCN1	0.907
B2M	PTX3	0.907
ARG1	CTSD	0.907
GSDMD	CTSZ	0.907
GPC2	GPC1	0.907
DOCK2	VCL	0.907
HPSE	CTSD	0.907
ARG1	TIMP2	0.907
CHIT1	TCN1	0.906
CNN2	MMP8	0.906
GPC4	GPC2	0.906
ELANE	VCL	0.906
FRK	CRACR2A	0.906
HP	CTSZ	0.906
ARG1	CTSZ	0.906
ELANE	DOCK2	0.906
GSDMD	DOCK2	0.906
DOCK2	MMP8	0.906
QSOX1	CTSZ	0.906
B2M	GSDMD	0.906
LYZ	TCN1	0.906
QSOX1	PTX3	0.906
ELANE	NFKB1	0.906
ARG1	SLPI	0.906
PTPN6	VCL	0.906
NFKB1	CTSZ	0.906
LRG1	CFP	0.905
CXCL1	TCN1	0.905
FOLR3	CXCL1	0.905
OSCAR	ELANE	0.905
CHIT1	CTSZ	0.905
ELANE	CTSZ	0.905
PTPN6	CTSD	0.905
FOLR3	DOCK2	0.905
QSOX1	MMP8	0.905
GPC3	GPC5	0.905
HP	TCN1	0.905
FOLR3	QSOX1	0.905
ELANE	HPSE	0.905
PTPN6	CFP	0.905
GSDMD	CNN2	0.905
ARG1	LRG1	0.905
MMP8	NFKB1	0.905
CFP	VCL	0.905
ELANE	CHIT1	0.905
CHIT1	MMP8	0.905
OSCAR	CAMP	0.905
PTPN6	CAMP	0.904
CFP	MMP8	0.904
HPSE	LRG1	0.904
GSDMD	LRG1	0.904
AOC1	ARG1	0.904
SLPI	NFKB1	0.904
CXCL1	DOCK2	0.904
GSDMD	CFP	0.904
B2M	GHDC	0.904
ARMC8	NFKB1	0.904
FOLR3	ARG1	0.904
CYFIP1	FRK	0.904
HP	VCL	0.904
CNN2	TCN1	0.904
HPSE	DOCK2	0.904
CNN2	CFP	0.904
TIMP2	LYZ	0.904
HPSE	CTSZ	0.904
FRK	CNN2	0.904
B2M	HPSE	0.904
GPC6	GPC2	0.904
OSCAR	GSDMD	0.904
QSOX1	SLPI	0.904
PTPN6	KPNB1	0.904
DEFA4	DOCK2	0.904
B2M	CHIT1	0.904
PTX3	LYZ	0.904
PTPN6	CHIT1	0.904
HPSE	NFKB1	0.904
GSDMD	GHDC	0.904
CEP290	MMP8	0.904
HPSE	CFP	0.904
CYFIP1	DOCK2	0.904
QSOX1	HP	0.904
GHDC	CTSD	0.903
ARMC8	VCL	0.903
ELANE	QSOX1	0.903
SLPI	CTSZ	0.903
FOLR3	B2M	0.903
ACAA1	CTSZ	0.903
CYFIP1	QSOX1	0.903
CNN2	NFKB1	0.903
LYZ	VCL	0.903
OSCAR	CHIT1	0.903
OSCAR	B2M	0.903
PTPN6	LRG1	0.903
OSCAR	DEFA4	0.903
HSPG2	LYZ	0.903
ELANE	ACAA1	0.903
PTX3	CNN2	0.903
OSCAR	MMP8	0.903
SLPI	PTX3	0.903
FOLR3	CTSZ	0.903
CHIT1	LRG1	0.903
B2M	ACAA1	0.903
CHIT1	DOCK2	0.903
LCN2	CTSZ	0.903
OSCAR	CXCL1	0.903
CHIT1	DEFA4	0.903
KPNB1	CTSZ	0.903
FRK	CXCL1	0.903
CNN2	CTSZ	0.903
CHIT1	CFP	0.903
QSOX1	GHDC	0.903
LCN2	CFP	0.903
LRG1	TCN1	0.903
FOLR3	PTX3	0.903
OSCAR	ARG1	0.903
QSOX1	SDC2	0.903
ARG1	DOCK2	0.903
CAMP	DOCK2	0.903
CNN2	TIMP2	0.903
B2M	TCN1	0.903
CEP290	ARMC8	0.902
LRG1	CTSZ	0.902
CRACR2A	CFP	0.902
KPNB1	VCL	0.902
CTSZ	VCL	0.902
GSDMD	HPSE	0.902
LRG1	CAMP	0.902
TIMP2	DOCK2	0.902
GSDMD	NFKB1	0.902
LCN2	VCL	0.902
CYFIP1	PTPN6	0.902
CEP290	CRACR2A	0.902
AOC1	PTX3	0.902
CYFIP1	NFKB1	0.902
HPSE	GHDC	0.902
B2M	QSOX1	0.902
HPSE	CHIT1	0.902
ACAA1	VCL	0.902
AOC1	PTPN6	0.902
HP	DOCK2	0.902
LRG1	GHDC	0.902
FOLR3	LRG1	0.902
QSOX1	CNN2	0.902
ARG1	VCL	0.902
GSDMD	CTSD	0.902
CRACR2A	CNN2	0.902
PTX3	VCL	0.902
HP	ACAA1	0.902
LRG1	MMP8	0.902
LRG1	CTSD	0.902
ACAA1	LRG1	0.902
HPSE	CAMP	0.902
OSCAR	TCN1	0.902
HPSE	SLPI	0.902
HPSE	QSOX1	0.902
FRK	CHIT1	0.902
PTPN6	TCN1	0.902
CYFIP1	CTSD	0.902
CYFIP1	CTSZ	0.902
CYFIP1	KPNB1	0.902
CYFIP1	TIMP2	0.902
LCN2	CNN2	0.902
OSCAR	NFKB1	0.902
HPSE	ARG1	0.902
GHDC	TIMP2	0.902
GHDC	LYZ	0.902
QSOX1	ARG1	0.902
FRK	B2M	0.902
KPNB1	DOCK2	0.902
PTPN6	SLPI	0.902
FRK	GSDMD	0.902
B2M	CNN2	0.902
PTPN6	LCN2	0.902
OSCAR	LRG1	0.902
HP	DEFA4	0.902
PTPN6	QSOX1	0.902
ARMC8	LRG1	0.902
CHIT1	ACAA1	0.902
GSDMD	ARG1	0.902
LRG1	DOCK2	0.902
CRACR2A	HPSE	0.902
CXCL1	LRG1	0.902
ARMC8	PTPN6	0.902
CYFIP1	CEP290	0.902
ELANE	AOC1	0.902
CHIT1	HP	0.902
CFP	CTSZ	0.902
QSOX1	CFP	0.902
PTPN6	CXCL1	0.902
CNN2	LYZ	0.902
GSDMD	HP	0.902
ELANE	PTPN6	0.902
FOLR3	SLPI	0.902
AOC1	VCL	0.902
B2M	AOC1	0.902
B2M	CEP290	0.902
GHDC	DOCK2	0.902
GSDMD	SLPI	0.902
PTX3	NFKB1	0.902
SLPI	DOCK2	0.902
FRK	ARG1	0.902
GSDMD	MMP8	0.902
ACAA1	CTSD	0.902
PTPN6	DEFA4	0.902
CHIT1	TIMP2	0.902
CXCL1	CNN2	0.902
CFP	NFKB1	0.902
ELANE	LRG1	0.902
AOC1	CTSZ	0.902
OSCAR	CTSD	0.902
GSDMD	CXCL1	0.902
FRK	SLPI	0.902
ACAA1	CFP	0.902
GHDC	CFP	0.902
AOC1	LRG1	0.902
HPSE	CNN2	0.902
CRACR2A	CTSZ	0.901
TIMP2	TCN1	0.901
AOC1	SLPI	0.901
FOLR3	LCN2	0.901
AOC1	CAMP	0.901
ELANE	CNN2	0.901
FOLR3	GSDMD	0.901
OSCAR	VCL	0.901
DOCK2	CTSD	0.901
HPSE	ACAA1	0.901
TIMP2	CFP	0.901
GSDMD	DEFA4	0.901
KPNB1	LYZ	0.901
PTPN6	MMP8	0.901
CXCL1	CHIT1	0.901
CAMP	NFKB1	0.901
FRK	KPNB1	0.901
ARMC8	CTSZ	0.901
ARMC8	CNN2	0.901
AOC1	CTSD	0.901
PTPN6	HPSE	0.901
SLPI	CNN2	0.901
GSDMD	CHIT1	0.901
OSCAR	HP	0.901
SLPI	VCL	0.901
ACAA1	TIMP2	0.901
PTX3	CTSD	0.901
CRACR2A	QSOX1	0.901
AOC1	CRACR2A	0.901
CYFIP1	CRACR2A	0.901
ARMC8	CTSD	0.901
CHIT1	VCL	0.901
B2M	CRACR2A	0.901
DEFA4	PTX3	0.901
CHIT1	NFKB1	0.901
TCN1	CFP	0.901
FOLR3	HPSE	0.901
HPSE	DEFA4	0.901
AOC1	GHDC	0.901
ACAA1	PTX3	0.9
ARMC8	SLPI	0.9
CAMP	TIMP2	0.9
TCN1	DOCK2	0.9
DEFA4	CTSZ	0.9
QSOX1	NFKB1	0.9
AOC1	TCN1	0.9
AOC1	DEFA4	0.9
FRK	CTSZ	0.9
LCN2	GHDC	0.9
FOLR3	CTSD	0.9
CEP290	CTSD	0.9
FRK	PTX3	0.9
ARG1	KPNB1	0.9
CYFIP1	CHIT1	0.9
OSCAR	QSOX1	0.9
LRG1	CNN2	0.9
ARG1	GHDC	0.9
CAMP	CTSZ	0.9
ARMC8	TCN1	0.9
CRACR2A	GHDC	0.9
CEP290	LCN2	0.9
CEP290	HPSE	0.9
CRACR2A	LCN2	0.9
ARMC8	ARG1	0.9
FRK	HPSE	0.9
ACAA1	MMP8	0.9
CEP290	AOC1	0.9
CAMP	CNN2	0.9
CEP290	KPNB1	0.9
CRACR2A	VCL	0.9
FOLR3	HP	0.9
ACAA1	TCN1	0.9
GSDMD	ARMC8	0.9
FOLR3	PTPN6	0.9
CEP290	VCL	0.9
LRG1	NFKB1	0.9
AOC1	KPNB1	0.9
ARMC8	CHIT1	0.9
FRK	QSOX1	0.9
FOLR3	AOC1	0.9
CYFIP1	CXCL1	0.9
CEP290	CAMP	0.9
HP	KPNB1	0.9
CRACR2A	PTPN6	0.9
FRK	TIMP2	0.9
CYFIP1	LYZ	0.9
CYFIP1	PTX3	0.9
ARMC8	GHDC	0.9
FRK	LCN2	0.9
CYFIP1	ARMC8	0.9
ARMC8	CXCL1	0.9
QSOX1	KPNB1	0.9
GSDMD	KPNB1	0.9
ARMC8	MMP8	0.9
CXCL1	KPNB1	0.9
ARMC8	ACAA1	0.9
CRACR2A	PTX3	0.9
CEP290	PTX3	0.9
CEP290	GSDMD	0.9
CHIT1	KPNB1	0.9
ARMC8	KPNB1	0.9
CRACR2A	ARG1	0.9
QSOX1	LYZ	0.9
ARMC8	HPSE	0.9
HP	CNN2	0.9
CYFIP1	OSCAR	0.9
PTX3	TCN1	0.9
FOLR3	VCL	0.9
CYFIP1	B2M	0.9
CEP290	CTSZ	0.9
LRG1	TIMP2	0.9
FOLR3	CRACR2A	0.9
CEP290	ARG1	0.9
PTPN6	ACAA1	0.9
CYFIP1	ARG1	0.9
PTPN6	TIMP2	0.9
KPNB1	MMP8	0.9
PTX3	KPNB1	0.9
ACAA1	KPNB1	0.9
CXCL1	DEFA4	0.9
CEP290	DEFA4	0.9
CEP290	DOCK2	0.9
OSCAR	SLPI	0.9
OSCAR	ACAA1	0.9
CEP290	ACAA1	0.9
CRACR2A	TCN1	0.9
GHDC	MMP8	0.9
ARMC8	HP	0.9
CEP290	TCN1	0.9
CEP290	NFKB1	0.9
FRK	CTSD	0.9
CRACR2A	CAMP	0.9
CRACR2A	KPNB1	0.9
CNN2	CTSD	0.9
CAMP	KPNB1	0.9
CYFIP1	CFP	0.9
AOC1	CHIT1	0.9
GSDMD	LCN2	0.9
GHDC	VCL	0.9
CYFIP1	SLPI	0.9
AOC1	HPSE	0.9
FRK	LRG1	0.9
AOC1	QSOX1	0.9
GSDMD	ACAA1	0.9
GHDC	CAMP	0.9
PTPN6	HP	0.9
LCN2	DOCK2	0.9
LCN2	KPNB1	0.9
CRACR2A	HP	0.9
ARMC8	DOCK2	0.9
ARMC8	QSOX1	0.9
CRACR2A	DOCK2	0.9
CRACR2A	ACAA1	0.9
B2M	DEFA4	0.9
FRK	ACAA1	0.9
TCN1	CTSZ	0.9
AOC1	DOCK2	0.9
FOLR3	TIMP2	0.9
CYFIP1	LRG1	0.9
TCN1	VCL	0.9
FOLR3	CHIT1	0.9
CEP290	GHDC	0.9
FOLR3	ACAA1	0.9
CYFIP1	ELANE	0.9
ARMC8	AOC1	0.9
QSOX1	ACAA1	0.9
HPSE	PTX3	0.9
CYFIP1	DEFA4	0.9
OSCAR	GHDC	0.9
CRACR2A	MMP8	0.9
OSCAR	ARMC8	0.9
FRK	CEP290	0.9
DEFA4	CTSD	0.9
ACAA1	CAMP	0.9
CHIT1	GHDC	0.9
CHIT1	PTX3	0.9
OSCAR	FRK	0.9
ELANE	ARMC8	0.9
OSCAR	LCN2	0.9
CEP290	PTPN6	0.9
CEP290	CFP	0.9
FRK	MMP8	0.9
OSCAR	PTX3	0.9
CRACR2A	DEFA4	0.9
SLPI	ACAA1	0.9
HPSE	LCN2	0.9
LCN2	QSOX1	0.9
FOLR3	FRK	0.9
CRACR2A	SLPI	0.9
DEFA4	CNN2	0.9
CRACR2A	LYZ	0.9
GPC3	QSOX1	0.9
CYFIP1	GSDMD	0.9
CEP290	CXCL1	0.9
AOC1	CXCL1	0.9
CEP290	SLPI	0.9
B2M	ARMC8	0.9
CRACR2A	LRG1	0.9
DEFA4	NFKB1	0.9
ELANE	KPNB1	0.9
GHDC	CNN2	0.9
GHDC	NFKB1	0.9
GSDMD	TIMP2	0.9
CRACR2A	CXCL1	0.9
FOLR3	GHDC	0.9
FRK	GHDC	0.9
OSCAR	CRACR2A	0.9
B2M	KPNB1	0.9
FOLR3	CYFIP1	0.9
KPNB1	CNN2	0.9
OSCAR	CNN2	0.9
ARMC8	CRACR2A	0.9
FRK	NFKB1	0.9
FOLR3	NFKB1	0.9
QSOX1	DEFA4	0.9
ACAA1	DEFA4	0.9
CRACR2A	NFKB1	0.9
ELANE	CEP290	0.9
ARMC8	CFP	0.9
FRK	CAMP	0.9
CYFIP1	ACAA1	0.9
CYFIP1	GHDC	0.9
FOLR3	ARMC8	0.9
QSOX1	DOCK2	0.9
FRK	ARMC8	0.9
HPSE	CXCL1	0.9
FOLR3	KPNB1	0.9
AOC1	TIMP2	0.9
ARMC8	CAMP	0.9
GSDMD	AOC1	0.9
PTX3	DOCK2	0.9
CEP290	CHIT1	0.9
CRACR2A	TIMP2	0.9
DEFA4	VCL	0.9
CEP290	CNN2	0.9
ACAA1	GHDC	0.9
AOC1	NFKB1	0.9
CYFIP1	AOC1	0.9
CXCL1	ACAA1	0.9
CRACR2A	CTSD	0.9
FRK	AOC1	0.9
ARMC8	PTX3	0.9
ARMC8	LCN2	0.9
CRACR2A	CHIT1	0.9
CEP290	LYZ	0.9
GSDMD	PTX3	0.9
ACAA1	LYZ	0.9
LCN2	ACAA1	0.9
LRG1	VCL	0.9
DEFA4	TIMP2	0.9
AOC1	MMP8	0.9
CYFIP1	HPSE	0.9
CEP290	LRG1	0.9
QSOX1	CHIT1	0.9
GSDMD	CRACR2A	0.9
ELANE	CRACR2A	0.9
CAMP	VCL	0.9
PTPN6	PTX3	0.9
ELANE	GSDMD	0.9
QSOX1	CAMP	0.9
ACAA1	CNN2	0.9
CXCL1	GHDC	0.9
QSOX1	VCL	0.9
KPNB1	CFP	0.9
CYFIP1	LCN2	0.9
CYFIP1	CAMP	0.9
GHDC	PTX3	0.9
AOC1	CFP	0.9
FRK	CFP	0.9
ARMC8	TIMP2	0.9
AOC1	CNN2	0.9
ARMC8	LYZ	0.9
GSDMD	QSOX1	0.9
OSCAR	TIMP2	0.9
GSDMD	VCL	0.9
ELANE	GHDC	0.9
QSOX1	TCN1	0.9
OSCAR	AOC1	0.9
PTPN6	CNN2	0.9
OSCAR	CEP290	0.9
CYFIP1	MMP8	0.9
GHDC	DEFA4	0.9
FRK	HP	0.9
OSCAR	HPSE	0.9
FRK	DEFA4	0.9
CYFIP1	CNN2	0.9
HP	GHDC	0.9
ARG1	CNN2	0.9
TCN1	NFKB1	0.9
LRG1	KPNB1	0.9
TCN1	CTSD	0.9
FOLR3	CNN2	0.9
FRK	TCN1	0.9
GHDC	TCN1	0.9
SLPI	KPNB1	0.9
GHDC	KPNB1	0.9
SLPI	GHDC	0.9
KPNB1	CTSD	0.9
ARMC8	DEFA4	0.9
CEP290	HP	0.9
CEP290	QSOX1	0.9
GSDMD	TCN1	0.9
KPNB1	TIMP2	0.9
OSCAR	KPNB1	0.9
DEFA4	KPNB1	0.9
ACAA1	DOCK2	0.9
FRK	LYZ	0.9
CEP290	TIMP2	0.9
FRK	ELANE	0.9
FOLR3	CEP290	0.9

Gene Ontology Semantic Similarity

Download Tab separated file

#	1991 (ELANE)	3339 (HSPG2)	1669 (DEFA4)	6382 (SDC1)	2239 (GPC4)	10082 (GPC6)	6383 (SDC2)	7077 (TIMP2)	3934 (LCN2)	6385 (SDC4)	375790 (AGRN)	9672 (SDC3)	2719 (GPC3)	6590 (SLPI)	1509 (CTSD)	1118 (CHIT1)	2919 (CXCL1)	3240 (HP)	567 (B2M)	1265 (CNN2)	10855 (HPSE)	383 (ARG1)	5777 (PTPN6)	23191 (CYFIP1)	4069 (LYZ)	2352 (FOLR3)	820 (CAMP)	2444 (FRK)	5806 (PTX3)	30 (ACAA1)	4317 (MMP8)	3837 (KPNB1)	5768 (QSOX1)	26 (AOC1)	116844 (LRG1)	126014 (OSCAR)	79792 (GSDMD)	4790 (NFKB1)	1794 (DOCK2)	84514 (GHDC)	5199 (CFP)	221914 (GPC2)	25852 (ARMC8)	80184 (CEP290)	84766 (CRACR2A)	1522 (CTSZ)	2817 (GPC1)	7414 (VCL)
1991 (ELANE)	1.00	0.51	0.61	0.56	0.14	0.46	0.55	0.49	0.32	0.50	0.54	0.53	0.46	0.46	0.75	0.42	0.39	0.74	0.53	0.69	0.59	0.54	0.48	0.49	0.48	0.20	0.42	0.48	0.54	0.45	0.58	0.52	0.18	0.45	0.55	0.14	0.47	0.43	0.47	0.48	0.73	1.00	1.00	0.53	0.49	0.69	0.39	0.58
3339 (HSPG2)	0.51	1.00	0.61	0.80	0.14	0.63	0.73	0.55	0.32	0.66	0.64	0.74	0.63	0.54	0.50	0.29	0.55	0.65	0.74	0.69	0.62	0.59	0.51	0.61	0.52	0.20	0.42	0.60	0.71	0.51	0.20	0.63	0.13	0.38	0.71	0.14	0.51	0.49	0.62	0.48	0.63	1.00	1.00	0.74	0.66	0.51	0.51	0.72
1669 (DEFA4)	0.61	0.61	1.00	0.75	0.09	0.61	0.75	0.61	0.19	0.75	0.61	0.75	0.61	0.61	0.61	0.29	0.49	0.61	0.75	0.42	0.75	0.61	0.61	0.61	0.75	0.13	0.26	0.61	0.75	0.61	0.19	0.61	0.09	1.00	0.61	0.09	0.61	0.75	0.61	0.27	0.61	0.61	0.61	0.75	0.61	0.61	0.44	0.61
6382 (SDC1)	0.56	0.80	0.75	1.00	0.14	0.75	0.92	0.61	0.32	0.83	0.58	0.96	0.76	0.60	0.57	0.32	0.60	0.76	0.96	0.69	0.70	0.68	0.56	0.69	0.73	0.20	0.42	0.67	0.86	0.58	0.22	0.70	0.14	0.43	0.82	0.14	0.56	0.54	0.72	0.48	0.75	1.00	1.00	0.96	0.80	0.58	0.60	0.79
2239 (GPC4)	0.14	0.14	0.09	0.14	1.00	1.00	0.14	0.14	0.07	0.60	0.14	0.14	0.14	0.14	0.14	0.11	0.11	0.14	0.14	0.10	0.14	0.14	0.32	0.14	0.11	0.71	0.10	0.14	0.14	0.14	0.08	0.14	0.08	0.14	0.25	0.48	0.14	0.14	0.14	0.25	0.14	0.14	0.14	0.14	0.14	0.14	0.10	0.14
10082 (GPC6)	0.46	0.63	0.61	0.75	1.00	1.00	0.73	0.49	0.32	0.80	0.49	0.74	0.57	0.48	0.42	0.26	0.48	0.62	0.74	0.69	0.58	0.52	0.50	0.57	0.48	0.71	0.42	0.53	0.69	0.43	0.19	0.60	0.13	0.37	0.68	0.48	0.45	0.45	0.57	0.48	0.57	1.00	1.00	0.74	0.62	0.43	0.51	0.71
6383 (SDC2)	0.55	0.73	0.75	0.92	0.14	0.73	1.00	0.60	0.32	0.81	0.56	0.94	0.73	0.58	0.55	0.31	0.59	0.74	0.94	0.69	0.68	0.66	0.55	0.67	0.71	0.20	0.42	0.65	0.84	0.56	0.21	0.71	0.14	0.43	0.80	0.14	0.55	0.53	0.70	0.48	0.73	1.00	1.00	0.94	0.77	0.56	0.58	0.77
7077 (TIMP2)	0.49	0.55	0.61	0.61	0.14	0.49	0.60	1.00	0.75	0.53	0.51	0.58	0.76	0.71	0.40	0.25	0.53	0.53	0.58	0.69	0.52	0.58	0.43	0.51	0.40	0.20	0.42	0.48	0.59	0.41	0.34	0.68	0.11	0.48	0.56	0.14	0.43	0.44	0.52	0.48	0.48	1.00	1.00	0.58	0.60	0.41	0.54	0.63
3934 (LCN2)	0.32	0.32	0.19	0.32	0.07	0.32	0.32	0.75	1.00	0.32	0.63	0.32	0.32	0.32	0.32	0.25	0.25	0.32	0.32	0.21	0.32	0.75	0.32	0.32	0.25	0.12	0.23	0.32	0.32	0.32	0.75	0.75	0.08	0.75	0.32	0.08	0.32	0.32	0.32	0.26	0.32	0.32	0.32	0.32	0.63	0.32	0.75	0.32
6385 (SDC4)	0.50	0.66	0.75	0.83	0.60	0.80	0.81	0.53	0.32	1.00	0.52	0.84	0.63	0.52	0.48	0.28	0.52	0.65	0.84	0.69	0.62	0.58	0.55	0.61	0.62	0.88	0.42	0.58	0.77	0.49	0.20	0.63	0.14	0.41	0.72	0.62	0.49	0.50	0.62	0.48	0.62	1.00	1.00	0.84	0.67	0.49	0.52	0.72
375790 (AGRN)	0.54	0.64	0.61	0.58	0.14	0.49	0.56	0.51	0.63	0.52	1.00	0.55	0.49	0.47	0.43	0.33	0.42	0.52	0.55	0.69	0.52	0.53	0.45	0.51	0.41	0.20	0.45	0.49	0.56	0.44	0.27	0.57	0.12	0.54	0.56	0.14	0.53	0.45	0.50	0.48	0.49	1.00	1.00	0.55	0.63	0.44	0.53	0.65
9672 (SDC3)	0.53	0.74	0.75	0.96	0.14	0.74	0.94	0.58	0.32	0.84	0.55	1.00	0.74	0.57	0.53	0.31	0.59	0.75	1.00	0.69	0.68	0.66	0.53	0.67	0.74	0.20	0.42	0.65	0.87	0.54	0.22	0.69	0.15	0.43	0.82	0.14	0.53	0.52	0.71	0.48	0.73	1.00	1.00	1.00	0.79	0.54	0.60	0.78
2719 (GPC3)	0.46	0.63	0.61	0.76	0.14	0.57	0.73	0.76	0.32	0.63	0.49	0.74	1.00	0.69	0.42	0.26	0.59	0.62	0.74	0.69	0.58	0.52	0.45	0.57	0.48	0.20	0.42	0.53	0.69	0.43	0.19	0.60	0.14	0.37	0.68	0.14	0.45	0.45	0.58	0.48	0.57	1.00	1.00	0.74	0.62	0.43	0.51	0.71
6590 (SLPI)	0.46	0.54	0.61	0.60	0.14	0.48	0.58	0.71	0.32	0.52	0.47	0.57	0.69	1.00	0.41	0.26	0.49	0.52	0.57	0.69	0.52	0.47	0.44	0.59	0.40	0.20	0.42	0.48	0.57	0.42	0.18	0.67	0.11	0.36	0.55	0.14	0.43	0.54	0.50	0.48	0.48	1.00	1.00	0.57	0.51	0.42	0.41	0.62
1509 (CTSD)	0.75	0.50	0.61	0.57	0.14	0.42	0.55	0.40	0.32	0.48	0.43	0.53	0.42	0.41	1.00	0.34	0.37	0.86	0.53	0.69	0.55	0.48	0.42	0.47	0.45	0.20	0.42	0.43	0.55	0.36	0.70	0.50	0.16	0.34	0.52	0.14	0.38	0.41	0.44	0.48	0.86	1.00	1.00	0.53	0.45	0.81	0.39	0.60
1118 (CHIT1)	0.42	0.29	0.29	0.32	0.11	0.26	0.31	0.25	0.25	0.28	0.33	0.31	0.26	0.26	0.34	1.00	0.22	0.35	0.31	0.33	0.63	0.38	0.29	0.29	0.64	0.17	0.58	0.28	0.33	0.28	0.32	0.31	0.20	0.31	0.37	0.12	0.27	0.25	0.26	0.38	0.35	0.48	0.48	0.31	0.29	0.38	0.23	0.34
2919 (CXCL1)	0.39	0.55	0.49	0.60	0.11	0.48	0.59	0.53	0.25	0.52	0.42	0.59	0.59	0.49	0.37	0.22	1.00	0.51	0.59	0.56	0.48	0.45	0.38	0.47	0.40	0.17	0.34	0.54	0.56	0.38	0.16	0.49	0.11	0.31	0.57	0.12	0.38	0.38	0.56	0.38	0.48	0.82	0.82	0.59	0.52	0.38	0.41	0.57
3240 (HP)	0.74	0.65	0.61	0.76	0.14	0.62	0.74	0.53	0.32	0.65	0.52	0.75	0.62	0.52	0.86	0.35	0.51	1.00	0.75	0.69	0.66	0.61	0.51	0.60	0.57	0.20	0.42	0.57	0.71	0.49	0.60	0.62	0.15	0.38	0.70	0.14	0.49	0.47	0.61	0.48	0.96	1.00	1.00	0.75	0.66	0.72	0.52	0.72
567 (B2M)	0.53	0.74	0.75	0.96	0.14	0.74	0.94	0.58	0.32	0.84	0.55	1.00	0.74	0.57	0.53	0.31	0.59	0.75	1.00	0.69	0.68	0.66	0.53	0.67	0.74	0.20	0.42	0.65	0.87	0.54	0.22	0.69	0.15	0.43	0.82	0.14	0.53	0.52	0.71	0.48	0.73	1.00	1.00	1.00	0.79	0.54	0.60	0.78
1265 (CNN2)	0.69	0.69	0.42	0.69	0.10	0.69	0.69	0.69	0.21	0.69	0.69	0.69	0.69	0.69	0.69	0.33	0.56	0.69	0.69	1.00	0.69	0.69	0.69	0.69	0.56	0.15	0.29	0.69	0.69	0.69	0.21	0.69	0.11	0.42	0.69	0.10	0.69	0.69	0.69	0.32	0.69	0.69	0.69	0.69	0.69	0.69	0.49	1.00
10855 (HPSE)	0.59	0.62	0.75	0.70	0.14	0.58	0.68	0.52	0.32	0.62	0.52	0.68	0.58	0.52	0.55	0.63	0.48	0.66	0.68	0.69	1.00	0.62	0.53	0.58	0.73	0.20	0.42	0.56	0.66	0.51	0.30	0.60	0.17	0.41	0.67	0.14	0.49	0.49	0.58	0.48	0.63	1.00	1.00	0.68	0.61	0.58	0.48	0.68
383 (ARG1)	0.54	0.59	0.61	0.68	0.14	0.52	0.66	0.58	0.75	0.58	0.53	0.66	0.52	0.47	0.48	0.38	0.45	0.61	0.66	0.69	0.62	1.00	0.47	0.54	0.51	0.20	0.42	0.51	0.64	0.44	0.43	0.67	0.16	0.49	0.62	0.14	0.43	0.44	0.53	0.48	0.57	1.00	1.00	0.66	0.69	0.51	0.62	0.67
5777 (PTPN6)	0.48	0.51	0.61	0.56	0.32	0.50	0.55	0.43	0.32	0.55	0.45	0.53	0.45	0.44	0.42	0.29	0.38	0.51	0.53	0.69	0.53	0.47	1.00	0.48	0.41	0.49	0.42	0.45	0.54	0.39	0.21	0.52	0.11	0.33	0.51	0.54	0.41	0.42	0.46	0.48	0.47	1.00	1.00	0.53	0.47	0.43	0.38	0.59
23191 (CYFIP1)	0.49	0.61	0.61	0.69	0.14	0.57	0.67	0.51	0.32	0.61	0.51	0.67	0.57	0.59	0.47	0.29	0.47	0.60	0.67	0.69	0.58	0.54	0.48	1.00	0.47	0.20	0.42	0.55	0.65	0.48	0.20	0.68	0.12	0.45	0.62	0.14	0.48	0.50	0.58	0.48	0.57	1.00	1.00	0.67	0.60	0.48	0.47	0.69
4069 (LYZ)	0.48	0.52	0.75	0.73	0.11	0.48	0.71	0.40	0.25	0.62	0.41	0.74	0.48	0.40	0.45	0.64	0.40	0.57	0.74	0.56	0.73	0.51	0.41	0.47	1.00	0.17	0.34	0.46	0.66	0.40	0.29	0.49	0.18	0.36	0.57	0.12	0.37	0.40	0.47	0.38	0.54	0.82	0.82	0.74	0.52	0.48	0.42	0.58
2352 (FOLR3)	0.20	0.20	0.13	0.20	0.71	0.71	0.20	0.20	0.12	0.88	0.20	0.20	0.20	0.20	0.20	0.17	0.17	0.20	0.20	0.15	0.20	0.20	0.49	0.20	0.17	1.00	0.15	0.20	0.20	0.20	0.13	0.20	0.13	0.20	0.34	0.72	0.20	0.20	0.20	0.34	0.20	0.20	0.20	0.20	0.20	0.20	0.15	0.20
820 (CAMP)	0.42	0.42	0.26	0.42	0.10	0.42	0.42	0.42	0.23	0.42	0.45	0.42	0.42	0.42	0.42	0.58	0.34	0.42	0.42	0.29	0.42	0.42	0.42	0.42	0.34	0.15	1.00	0.42	0.42	0.42	0.23	0.42	0.11	0.42	0.42	0.11	0.43	0.42	0.42	0.32	0.42	0.42	0.42	0.42	0.42	0.42	0.31	0.45
2444 (FRK)	0.48	0.60	0.61	0.67	0.14	0.53	0.65	0.48	0.32	0.58	0.49	0.65	0.53	0.48	0.43	0.28	0.54	0.57	0.65	0.69	0.56	0.51	0.45	0.55	0.46	0.20	0.42	1.00	0.63	0.50	0.20	0.57	0.15	0.36	0.62	0.14	0.45	0.45	0.56	0.48	0.53	1.00	1.00	0.65	0.57	0.44	0.46	0.66
5806 (PTX3)	0.54	0.71	0.75	0.86	0.14	0.69	0.84	0.59	0.32	0.77	0.56	0.87	0.69	0.57	0.55	0.33	0.56	0.71	0.87	0.69	0.66	0.64	0.54	0.65	0.66	0.20	0.42	0.63	1.00	0.56	0.22	0.67	0.14	0.43	0.75	0.14	0.54	0.53	0.68	0.48	0.69	1.00	1.00	0.87	0.73	0.55	0.55	0.75
30 (ACAA1)	0.45	0.51	0.61	0.58	0.14	0.43	0.56	0.41	0.32	0.49	0.44	0.54	0.43	0.42	0.36	0.28	0.38	0.49	0.54	0.69	0.51	0.44	0.39	0.48	0.40	0.20	0.42	0.50	0.56	1.00	0.21	0.51	0.21	0.38	0.55	0.14	0.39	0.42	0.45	0.48	0.43	1.00	1.00	0.54	0.47	0.39	0.39	0.61
4317 (MMP8)	0.58	0.20	0.19	0.22	0.08	0.19	0.21	0.34	0.75	0.20	0.27	0.22	0.19	0.18	0.70	0.32	0.16	0.60	0.22	0.21	0.30	0.43	0.21	0.20	0.29	0.13	0.23	0.20	0.22	0.21	1.00	0.36	0.16	0.39	0.27	0.09	0.22	0.17	0.19	0.28	0.66	0.32	0.32	0.22	0.33	0.60	0.32	0.21
3837 (KPNB1)	0.52	0.63	0.61	0.70	0.14	0.60	0.71	0.68	0.75	0.63	0.57	0.69	0.60	0.67	0.50	0.31	0.49	0.62	0.69	0.69	0.60	0.67	0.52	0.68	0.49	0.20	0.42	0.57	0.67	0.51	0.36	1.00	0.12	0.52	0.64	0.14	0.51	0.54	0.60	0.48	0.60	1.00	1.00	0.69	0.70	0.51	0.59	0.70
5768 (QSOX1)	0.18	0.13	0.09	0.14	0.08	0.13	0.14	0.11	0.08	0.14	0.12	0.15	0.14	0.11	0.16	0.20	0.11	0.15	0.15	0.11	0.17	0.16	0.11	0.12	0.18	0.13	0.11	0.15	0.14	0.21	0.16	0.12	1.00	0.17	0.25	0.09	0.10	0.11	0.13	0.28	0.15	0.16	0.16	0.15	0.14	0.18	0.10	0.12
26 (AOC1)	0.45	0.38	1.00	0.43	0.14	0.37	0.43	0.48	0.75	0.41	0.54	0.43	0.37	0.36	0.34	0.31	0.31	0.38	0.43	0.42	0.41	0.49	0.33	0.45	0.36	0.20	0.42	0.36	0.43	0.38	0.39	0.52	0.17	1.00	0.42	0.14	0.40	0.36	0.38	0.48	0.37	0.61	0.61	0.43	0.53	0.35	0.46	0.40
116844 (LRG1)	0.55	0.71	0.61	0.82	0.25	0.68	0.80	0.56	0.32	0.72	0.56	0.82	0.68	0.55	0.52	0.37	0.57	0.70	0.82	0.69	0.67	0.62	0.51	0.62	0.57	0.34	0.42	0.62	0.75	0.55	0.27	0.64	0.25	0.42	1.00	0.24	0.49	0.52	0.66	1.00	0.67	1.00	1.00	0.82	0.71	0.54	0.55	0.75
126014 (OSCAR)	0.14	0.14	0.09	0.14	0.48	0.48	0.14	0.14	0.08	0.62	0.14	0.14	0.14	0.14	0.14	0.12	0.12	0.14	0.14	0.10	0.14	0.14	0.54	0.14	0.12	0.72	0.11	0.14	0.14	0.14	0.09	0.14	0.09	0.14	0.24	1.00	0.14	0.14	0.14	0.24	0.14	0.14	0.14	0.14	0.14	0.14	0.11	0.14
79792 (GSDMD)	0.47	0.51	0.61	0.56	0.14	0.45	0.55	0.43	0.32	0.49	0.53	0.53	0.45	0.43	0.38	0.27	0.38	0.49	0.53	0.69	0.49	0.43	0.41	0.48	0.37	0.20	0.43	0.45	0.54	0.39	0.22	0.51	0.10	0.40	0.49	0.14	1.00	0.42	0.46	0.48	0.44	1.00	1.00	0.53	0.47	0.39	0.40	0.59
4790 (NFKB1)	0.43	0.49	0.75	0.54	0.14	0.45	0.53	0.44	0.32	0.50	0.45	0.52	0.45	0.54	0.41	0.25	0.38	0.47	0.52	0.69	0.49	0.44	0.42	0.50	0.40	0.20	0.42	0.45	0.53	0.42	0.17	0.54	0.11	0.36	0.52	0.14	0.42	1.00	0.46	0.48	0.45	1.00	1.00	0.52	0.47	0.42	0.36	0.54
1794 (DOCK2)	0.47	0.62	0.61	0.72	0.14	0.57	0.70	0.52	0.32	0.62	0.50	0.71	0.58	0.50	0.44	0.26	0.56	0.61	0.71	0.69	0.58	0.53	0.46	0.58	0.47	0.20	0.42	0.56	0.68	0.45	0.19	0.60	0.13	0.38	0.66	0.14	0.46	0.46	1.00	0.48	0.57	1.00	1.00	0.71	0.61	0.45	0.49	0.69
84514 (GHDC)	0.48	0.48	0.27	0.48	0.25	0.48	0.48	0.48	0.26	0.48	0.48	0.48	0.48	0.48	0.48	0.38	0.38	0.48	0.48	0.32	0.48	0.48	0.48	0.48	0.38	0.34	0.32	0.48	0.48	0.48	0.28	0.48	0.28	0.48	1.00	0.24	0.48	0.48	0.48	1.00	0.48	0.48	0.48	0.48	0.48	0.48	0.32	0.48
5199 (CFP)	0.73	0.63	0.61	0.75	0.14	0.57	0.73	0.48	0.32	0.62	0.49	0.73	0.57	0.48	0.86	0.35	0.48	0.96	0.73	0.69	0.63	0.57	0.47	0.57	0.54	0.20	0.42	0.53	0.69	0.43	0.66	0.60	0.15	0.37	0.67	0.14	0.44	0.45	0.57	0.48	1.00	1.00	1.00	0.73	0.62	0.70	0.50	0.71
221914 (GPC2)	1.00	1.00	0.61	1.00	0.14	1.00	1.00	1.00	0.32	1.00	1.00	1.00	1.00	1.00	1.00	0.48	0.82	1.00	1.00	0.69	1.00	1.00	1.00	1.00	0.82	0.20	0.42	1.00	1.00	1.00	0.32	1.00	0.16	0.61	1.00	0.14	1.00	1.00	1.00	0.48	1.00	1.00	1.00	1.00	1.00	1.00	0.71	1.00
25852 (ARMC8)	1.00	1.00	0.61	1.00	0.14	1.00	1.00	1.00	0.32	1.00	1.00	1.00	1.00	1.00	1.00	0.48	0.82	1.00	1.00	0.69	1.00	1.00	1.00	1.00	0.82	0.20	0.42	1.00	1.00	1.00	0.32	1.00	0.16	0.61	1.00	0.14	1.00	1.00	1.00	0.48	1.00	1.00	1.00	1.00	1.00	1.00	0.71	1.00
80184 (CEP290)	0.53	0.74	0.75	0.96	0.14	0.74	0.94	0.58	0.32	0.84	0.55	1.00	0.74	0.57	0.53	0.31	0.59	0.75	1.00	0.69	0.68	0.66	0.53	0.67	0.74	0.20	0.42	0.65	0.87	0.54	0.22	0.69	0.15	0.43	0.82	0.14	0.53	0.52	0.71	0.48	0.73	1.00	1.00	1.00	0.79	0.54	0.60	0.78
84766 (CRACR2A)	0.49	0.66	0.61	0.80	0.14	0.62	0.77	0.60	0.63	0.67	0.63	0.79	0.62	0.51	0.45	0.29	0.52	0.66	0.79	0.69	0.61	0.69	0.47	0.60	0.52	0.20	0.42	0.57	0.73	0.47	0.33	0.70	0.14	0.53	0.71	0.14	0.47	0.47	0.61	0.48	0.62	1.00	1.00	0.79	1.00	0.46	0.68	0.73
1522 (CTSZ)	0.69	0.51	0.61	0.58	0.14	0.43	0.56	0.41	0.32	0.49	0.44	0.54	0.43	0.42	0.81	0.38	0.38	0.72	0.54	0.69	0.58	0.51	0.43	0.48	0.48	0.20	0.42	0.44	0.55	0.39	0.60	0.51	0.18	0.35	0.54	0.14	0.39	0.42	0.45	0.48	0.70	1.00	1.00	0.54	0.46	1.00	0.39	0.61
2817 (GPC1)	0.39	0.51	0.44	0.60	0.10	0.51	0.58	0.54	0.75	0.52	0.53	0.60	0.51	0.41	0.39	0.23	0.41	0.52	0.60	0.49	0.48	0.62	0.38	0.47	0.42	0.15	0.31	0.46	0.55	0.39	0.32	0.59	0.10	0.46	0.55	0.11	0.40	0.36	0.49	0.32	0.50	0.71	0.71	0.60	0.68	0.39	1.00	0.55
7414 (VCL)	0.58	0.72	0.61	0.79	0.14	0.71	0.77	0.63	0.32	0.72	0.65	0.78	0.71	0.62	0.60	0.34	0.57	0.72	0.78	1.00	0.68	0.67	0.59	0.69	0.58	0.20	0.45	0.66	0.75	0.61	0.21	0.70	0.12	0.40	0.75	0.14	0.59	0.54	0.69	0.48	0.71	1.00	1.00	0.78	0.73	0.61	0.55	1.00

Association with High Altitude

Protein Official symbol	Source Organism	Tissue of Expression	Level of hypoxia	Altitude	Duration of experiment	Level of expression	Fold change	Experiment details	geographical location	ethnicity of the patients	Control group	Control (Fold change)	Reference (PMID)
HPSE	Human	Blood	-	3600 m	Native	upregulated	-	TMT-based proteomic analysis/LC-MS	Central Asia	Tibetans	-	High altitude native vs. low Lander	30908922

Association with TF

TF	TF Entrez	Gene	Gene Entrez	Type	PMID	Database
NFKB1	4790	HPSE	10855	Repression	19509297	TRUSST
EGR1	1958	HPSE	10855	Unknown	23926105	TRUSST
POU4F1	5457	HPSE	10855	Activation	14662017	TRUSST
RELA	5970	HPSE	10855	Unknown	20453883	TRUSST

Association with miRNA

miRTarBase ID	miRNA	Species (miRNA)	Protein Official Symbol	Human Entrez ID	Species (Target Gene)	Experiments	Support Type	References (PMID)
MIRT005537	hsa-miR-1258	Homo sapiens	HPSE	10855	Homo sapiens	Immunohistochemistry//In situ hybridization//Luciferase reporter assay//qRT-PCR	Functional MTI	21266359
MIRT530350	hsa-miR-190a-3p	Homo sapiens	HPSE	10855	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT530349	hsa-miR-3161	Homo sapiens	HPSE	10855	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT530351	hsa-miR-4536-5p	Homo sapiens	HPSE	10855	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT530356	hsa-miR-3681-5p	Homo sapiens	HPSE	10855	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT530357	hsa-miR-186-5p	Homo sapiens	HPSE	10855	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT530348	hsa-miR-1261	Homo sapiens	HPSE	10855	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT530352	hsa-miR-376c-5p	Homo sapiens	HPSE	10855	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT530355	hsa-miR-6849-5p	Homo sapiens	HPSE	10855	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT530354	hsa-miR-5011-5p	Homo sapiens	HPSE	10855	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT530358	hsa-miR-3133	Homo sapiens	HPSE	10855	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT530353	hsa-miR-376b-5p	Homo sapiens	HPSE	10855	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT673600	hsa-miR-26a-5p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT673601	hsa-miR-1297	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT673605	hsa-miR-4284	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT673619	hsa-miR-5697	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT673595	hsa-miR-5001-3p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT673607	hsa-miR-6791-3p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT673618	hsa-miR-6890-3p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT673596	hsa-miR-6783-3p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT673597	hsa-miR-1343-3p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT673598	hsa-miR-4465	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT673603	hsa-miR-23b-5p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT673609	hsa-miR-4772-3p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT673604	hsa-miR-23a-5p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT673614	hsa-miR-6742-3p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT673619	hsa-miR-5697	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT673612	hsa-miR-1304-3p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT673614	hsa-miR-6742-3p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT673594	hsa-miR-6836-3p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT673616	hsa-miR-939-3p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT673617	hsa-miR-660-3p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT673598	hsa-miR-4465	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT673599	hsa-miR-26b-5p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT673601	hsa-miR-1297	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT673610	hsa-miR-4638-5p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT673615	hsa-miR-6852-5p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT673602	hsa-miR-891a-3p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT673600	hsa-miR-26a-5p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT673606	hsa-miR-6829-3p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT673608	hsa-miR-6778-3p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT673613	hsa-miR-6741-3p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT673599	hsa-miR-26b-5p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT673611	hsa-miR-1307-3p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT680209	hsa-miR-4279	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT680209	hsa-miR-4279	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT680210	hsa-miR-5571-5p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT680210	hsa-miR-5571-5p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT685080	hsa-miR-324-3p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT685081	hsa-miR-1913	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT685087	hsa-miR-6849-3p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT685082	hsa-miR-1976	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT685084	hsa-miR-6747-3p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT685078	hsa-miR-4758-3p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT685083	hsa-miR-3653-5p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT685086	hsa-miR-4722-3p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT685085	hsa-miR-6727-3p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT685077	hsa-miR-3189-5p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT685079	hsa-miR-5699-5p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT702804	hsa-miR-4701-3p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT702809	hsa-miR-542-3p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT702805	hsa-miR-1262	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT702811	hsa-miR-766-3p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT702806	hsa-miR-183-5p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT702808	hsa-miR-6720-5p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT702810	hsa-miR-6776-5p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT702803	hsa-miR-6736-5p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT702807	hsa-miR-6512-3p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT702812	hsa-miR-508-5p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT702813	hsa-miR-7153-3p	Homo sapiens	HPSE	10855	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT733540	hsa-miR-558	Homo sapiens	HPSE	10855	Homo sapiens	ChIP-seq//Immunohistochemistry//Luciferase reporter assay//qRT-PCR//Western blot	Functional MTI	27685626

Gene Ontology

ID	GO ID	GO Term	GO Type
10855	GO:0007160	cell-matrix adhesion	GOTERM_BP_DIRECT
10855	GO:0043395	proteoglycan binding	GOTERM_MF_DIRECT
10855	GO:0016020	membrane	GOTERM_CC_DIRECT
10855	GO:0005975	carbohydrate metabolic process	GOTERM_BP_DIRECT
10855	GO:0030194	positive regulation of blood coagulation	GOTERM_BP_DIRECT
10855	GO:0005515	protein binding	GOTERM_MF_DIRECT
10855	GO:0016798	phosphatase activity	GOTERM_MF_DIRECT
10855	GO:0045545	chemorepellent activity	GOTERM_MF_DIRECT
10855	GO:0005764	lysosome	GOTERM_CC_DIRECT
10855	GO:0051897	positive regulation of protein kinase B signaling	GOTERM_BP_DIRECT
10855	GO:0043231	intracellular membrane-bounded organelle	GOTERM_CC_DIRECT
10855	GO:0033690	positive regulation of osteoblast proliferation	GOTERM_BP_DIRECT
10855	GO:0045121	membrane raft	GOTERM_CC_DIRECT
10855	GO:0006029	proteoglycan metabolic process	GOTERM_BP_DIRECT
10855	GO:0051797	regulation of hair follicle development	GOTERM_BP_DIRECT
10855	GO:0061042	vascular wound healing	GOTERM_BP_DIRECT
10855	GO:0030198	extracellular matrix organization	GOTERM_BP_DIRECT
10855	GO:0005765	lysosomal membrane	GOTERM_CC_DIRECT
10855	GO:0030200	heparan sulfate proteoglycan catabolic process	GOTERM_BP_DIRECT
10855	GO:0005654	nucleoplasm	GOTERM_CC_DIRECT
10855	GO:0004566	hydrolase activity	GOTERM_MF_DIRECT
10855	GO:0005578	proteinaceous extracellular matrix	GOTERM_CC_DIRECT
10855	GO:0005634	nucleus	GOTERM_CC_DIRECT
10855	GO:0043202	lysosomal lumen	GOTERM_CC_DIRECT
10855	GO:0051798	positive regulation of hair follicle development	GOTERM_BP_DIRECT
10855	GO:0060055	angiogenesis involved in wound healing	GOTERM_BP_DIRECT
10855	GO:0030305	protein kinase activator activity	GOTERM_MF_DIRECT
10855	GO:0046983	protein dimerization activity	GOTERM_MF_DIRECT
10855	GO:0006027	glycosaminoglycan catabolic process	GOTERM_BP_DIRECT
10855	GO:0010575	positive regulation of vascular endothelial growth factor production	GOTERM_BP_DIRECT

Pathways

Human Entrez ID	KEGG ID	KEGG Term
10855	hsa00531	Glycosaminoglycan degradation
10855	hsa01100	Metabolic pathways
10855	hsa05205	Proteoglycans in cancer

Association with Disease

Protein Official Symbol	Human Entrez ID	Disease Name	Disease Id	Disease Semantic Type	Semantic score	DSI	DPI	Disease Type
HPSE	10855	Liver Cirrhosis, Experimental	C0023893	Experimental Model of Disease	0.3	0.464	0.759	disease
HPSE	10855	Neoplasm Invasiveness	C0027626	Pathologic Function	0.3	0.464	0.759	phenotype
HPSE	10855	Mammary Neoplasms	C1458155	Neoplastic Process	0.32	0.464	0.759	group
HPSE	10855	Nephrosis	C0027720	Disease or Syndrome	0.3	0.464	0.759	disease
HPSE	10855	Mammary Neoplasms, Human	C1257931	Neoplastic Process	0.3	0.464	0.759	group
HPSE	10855	IGA Glomerulonephritis	C0017661	Disease or Syndrome	0.3	0.464	0.759	disease
HPSE	10855	Neoplasm Metastasis	C0027627	Neoplastic Process	0.4	0.464	0.759	phenotype
HPSE	10855	Malignant neoplasm of breast	C0006142	Neoplastic Process	0.4	0.464	0.759	disease
HPSE	10855	Breast Carcinoma	C0678222	Neoplastic Process	0.4	0.464	0.759	disease
HPSE	10855	melanoma	C0025202	Neoplastic Process	0.4	0.464	0.759	disease
HPSE	10855	Depressive disorder	C0011581	Mental or Behavioral Dysfunction	0.3	0.464	0.759	disease
HPSE	10855	Major Depressive Disorder	C1269683	Mental or Behavioral Dysfunction	0.31	0.464	0.759	disease
HPSE	10855	Depressive episode, unspecified	C0349217	Mental or Behavioral Dysfunction	0.3	0.464	0.759	disease
HPSE	10855	Unipolar Depression	C0041696	Mental or Behavioral Dysfunction	0.31	0.464	0.759	disease
HPSE	10855	Liver carcinoma	C2239176	Neoplastic Process	0.4	0.464	0.759	disease

Association with Drug

Protein Official Symbol	Human Entrez ID	drug_claim_primary_name	drug_name	drug_chembl_id	interaction_types
HPSE	10855	2-O, 3-O DESULFATED HEPARIN	None	None	None
HPSE	10855	ANTIESTROGEN	None	None	None
HPSE	10855	HEPARIN	HEPARIN	CHEMBL1909300	None
HPSE	10855	HEPARAN SULFATE	None	None	None
HPSE	10855	MUPARFOSTAT	MUPARFOSTAT (CHEMBL1615835)	CHEMBL1615835	inhibitor
HPSE	10855	PG545	None	None	None
HPSE	10855	PI-88	None	None	inhibitor
HPSE	10855	PI-88	None	None	None
HPSE	10855	TGF	None	None	None
HPSE	10855	THROMBIN	THROMBIN	CHEMBL2108110	None