ALTITUDEOMICSDB

14-3-3 protein theta

AltitudeomicsDB

Protein Official symbol	YWHAQ
Aliases	YWHAQ
Chromosomal Location	2
Length	245
Uniprot ID	P27348
EC number	None
Protein family Information(Pfam)	PF00244;
PDB id	2BTP;5IQP;6BCR;6BD2;6BQT;
InterPro ID	IPR000308;IPR023409;IPR036815;IPR023410;IPR042584;
dbSNP	None

Protein Protein Interaction

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AltitudeomicsDB

Protein 1	Protein 2	Combine Score
MTOR	RPTOR	0.999
AKT1	FOXO3	0.998
AKT1	MTOR	0.997
MLST8	RPTOR	0.996
PPP2CA	PPP2R1A	0.995
AKT1	CTNNB1	0.995
MLST8	MTOR	0.994
AKT1	TP53	0.993
HRAS	RAF1	0.989
RAN	XPO1	0.988
CDC25C	TP53	0.987
HRAS	MAP2K1	0.986
AKT1	RPTOR	0.986
AKT1	CDKN1B	0.986
PPP2CA	PPP2R2A	0.985
AKT1	FOXO4	0.984
TP53	CDKN1B	0.982
HRAS	MAPK3	0.981
PPP3CC	PPP3R1	0.98
HRAS	MAP2K2	0.98
FOXO3	CDKN1B	0.979
MAPK3	KRAS	0.979
NRAS	MAP2K1	0.979
MAP2K1	KRAS	0.979
HRAS	MAPK1	0.979
NRAS	RAF1	0.978
PPP2R2A	PPP2R1A	0.977
KRAS	RAF1	0.975
CSNK1A1	CTNNB1	0.974
AKT1	PPP2CA	0.973
KRAS	MAPK1	0.973
NRAS	MAPK3	0.973
MLST8	AKT1	0.972
TP53	MAPK1	0.971
MAP2K2	KRAS	0.97
NRAS	MAPK1	0.97
NRAS	MAP2K2	0.97
FOXO3	CTNNB1	0.964
CABIN1	MEF2D	0.963
FOXO3	YWHAZ	0.962
PPP2R2B	PPP2R1A	0.961
FOXO3	MAPK1	0.958
AKT1	MEF2D	0.957
AKT1	PPP2R1A	0.957
PPP2CA	PPP2R2B	0.957
AKT1	ITGB4	0.955
YWHAZ	CTNNB1	0.955
TP53	PIN1	0.955
PPP2CA	YWHAQ	0.953
CABIN1	TP53	0.952
RAB14	YWHAG	0.952
HRAS	TP53	0.952
YWHAG	YWHAE	0.952
CDC25C	YWHAG	0.951
CABIN1	CAMK4	0.951
RAB14	LNPEP	0.951
CTNNB1	PPP2R1A	0.95
CSNK1E	CTNNB1	0.95
PPP2R1A	KRAS	0.95
FOXO4	TP53	0.949
AKT1	YWHAZ	0.949
RAF1	YWHAH	0.948
HRAS	PPP2R1A	0.948
MAP2K1	MAPK3	0.948
MAPK3	MAP2K2	0.948
MAP2K1	MAPK1	0.947
TP53	MAPK3	0.946
MAP2K2	MAPK1	0.946
PPP2CA	PIN1	0.945
PPP2CA	MAPK3	0.944
PPP2R1A	TP53	0.943
FOXO3	XPO1	0.942
YWHAB	RAF1	0.942
MAP2K1	RAF1	0.942
RAN	YWHAQ	0.94
RAN	YWHAE	0.94
AKT1	YWHAB	0.94
FOXO3	MAPK3	0.939
RAB10	LNPEP	0.939
PPP2CA	YWHAZ	0.939
AKT1	YWHAQ	0.939
PPP2CA	MAP2K1	0.938
RAF1	MAPK1	0.938
PPP2CA	MAPK1	0.937
SIK1	TP53	0.937
XPO1	PPP2R1A	0.937
YWHAZ	TP53	0.937
VAMP2	LNPEP	0.937
AKT1	YWHAE	0.937
MAP2K2	RAF1	0.937
YWHAB	CDC25B	0.937
MAPK3	RAF1	0.936
RAN	YWHAZ	0.936
PPP2CA	MTOR	0.936
AKT1	RAF1	0.936
CTNNB1	CSNK1D	0.935
PPP2CA	YWHAB	0.935
YWHAZ	YWHAH	0.935
XPO1	YWHAQ	0.934
YWHAZ	RAF1	0.933
PPP2CA	TP53	0.933
CSNK1A1	PPP2CA	0.933
PPP2CA	YWHAG	0.933
RAN	YWHAB	0.933
CABIN1	YWHAQ	0.932
YWHAZ	RAB14	0.932
PPP2CA	YWHAH	0.932
YWHAB	PPP2R1A	0.932
CSNK1A1	TP53	0.932
YWHAE	CDC25B	0.931
YWHAB	YWHAE	0.931
AKT1	YWHAH	0.931
PPP2R1A	MAPK3	0.931
VAMP2	RAB10	0.93
FOXO3	YWHAE	0.93
AKT1	YWHAG	0.93
XPO1	CTNNB1	0.929
YWHAE	MAP2K2	0.929
TP53	YWHAE	0.929
YWHAQ	MAPK1	0.929
FOXO3	YWHAB	0.929
YWHAZ	MAPK1	0.929
YWHAQ	YWHAG	0.928
CSNK1A1	YWHAZ	0.928
YWHAB	CDC25C	0.928
MAP2K1	YWHAE	0.928
YWHAQ	PPP2R1A	0.928
CDC25C	YWHAE	0.928
CAMK4	MEF2D	0.927
YWHAZ	CDC25B	0.927
AKT1	LNPEP	0.927
CSNK1A1	PPP2R1A	0.927
YWHAE	MAPK1	0.926
PPP2R1A	MAPK1	0.926
HRAS	YWHAZ	0.926
YWHAQ	MEF2D	0.926
YWHAB	MTOR	0.925
YWHAG	MAPK1	0.925
YWHAQ	YWHAE	0.925
YWHAQ	PPP2R2A	0.925
HRAS	YWHAB	0.924
TP53	KRAS	0.924
RAN	YWHAH	0.924
YWHAZ	MTOR	0.924
FOXO4	YWHAG	0.924
FOXO3	YWHAQ	0.924
YWHAG	TP53	0.923
YWHAB	MAPK3	0.923
PPP2CA	CTNNB1	0.923
XPO1	FOXO4	0.923
CSNK1E	YWHAQ	0.922
PPP2CA	XPO1	0.922
RPTOR	YWHAH	0.922
RAB14	VAMP2	0.922
PPP2R1A	PPP3R1	0.922
YWHAZ	MAPK3	0.922
PPP2CA	YWHAE	0.922
YWHAQ	TP53	0.921
HRAS	YWHAQ	0.921
RAB10	YWHAH	0.921
MTOR	YWHAH	0.921
PPP2CA	HRAS	0.92
YWHAH	MAPK1	0.92
HRAS	ITGB4	0.92
RAB14	RAB10	0.92
CTNNB1	YWHAE	0.92
YWHAB	MAPK1	0.919
YWHAQ	MAPK3	0.919
YWHAQ	CTNNB1	0.919
PPP2R2A	YWHAG	0.919
FOXO3	YWHAH	0.919
HRAS	YWHAE	0.919
FOXO3	YWHAG	0.919
PPP2R1A	YWHAE	0.919
PPP2R1A	YWHAH	0.919
YWHAG	PPP3R1	0.918
YWHAZ	CDKN1B	0.918
RAN	YWHAG	0.918
PPP2CA	KRAS	0.918
YWHAZ	YWHAB	0.918
XPO1	YWHAZ	0.918
PPP2R1A	CSNK1D	0.918
PPP2R1A	MAP2K2	0.918
PPP2CA	RAF1	0.918
YWHAB	TP53	0.918
CSNK1E	TP53	0.917
YWHAZ	RAB10	0.917
YWHAB	CTNNB1	0.917
CTNNB1	MEF2D	0.917
PPP2R1A	YWHAG	0.917
YWHAB	MAP2K1	0.917
PIN1	MAPK1	0.917
FOXO4	CTNNB1	0.917
PPP2R1A	MAP2K1	0.917
HRAS	YWHAG	0.917
XPO1	YWHAE	0.917
PPP2R2A	PPP3R1	0.917
YWHAE	RAF1	0.917
XPO1	YWHAB	0.916
YWHAQ	MTOR	0.916
YWHAZ	NRAS	0.916
PPP2CA	PPP3R1	0.916
CSNK1D	YWHAE	0.916
PPP2R2A	RAF1	0.916
PPP2R2B	YWHAQ	0.916
YWHAZ	KRAS	0.916
YWHAB	YWHAG	0.916
YWHAZ	PPP2R1A	0.915
CSNK1E	PPP2R1A	0.915
CTNNB1	YWHAH	0.915
XPO1	YWHAH	0.915
CDC25C	CDC25B	0.915
YWHAZ	YWHAG	0.915
YWHAZ	MAP2K1	0.915
YWHAB	MAP2K2	0.915
CSNK1E	YWHAH	0.915
YWHAQ	YWHAB	0.914
PPP2CA	NRAS	0.914
YWHAG	RAB10	0.914
YWHAZ	YWHAE	0.914
YWHAQ	KRAS	0.914
YWHAE	MAPK3	0.914
PPP2CA	MAP2K2	0.913
CTNNB1	YWHAG	0.913
YWHAB	KRAS	0.913
YWHAG	MAP2K1	0.913
YWHAB	NRAS	0.913
YWHAG	YWHAH	0.913
YWHAB	CDKN1B	0.913
MLST8	YWHAQ	0.913
YWHAG	MAPK3	0.913
YWHAZ	PPP2R2A	0.912
MLST8	YWHAH	0.912
CSNK1D	TP53	0.912
MLST8	YWHAG	0.912
MLST8	YWHAB	0.912
TP53	YWHAH	0.912
YWHAE	CDKN1B	0.912
PPP2R2B	RAF1	0.912
MLST8	YWHAZ	0.912
MLST8	YWHAE	0.912
YWHAQ	YWHAH	0.911
CABIN1	PPP3CC	0.911
PPP2R2A	YWHAH	0.911
YWHAQ	CSNK1D	0.911
YWHAZ	YWHAQ	0.911
YWHAQ	CSNK1G3	0.911
HRAS	YWHAH	0.911
VAMP2	YWHAG	0.911
MAPK3	PIN1	0.91
XPO1	YWHAG	0.91
YWHAE	YWHAH	0.91
YWHAQ	RAB13	0.91
RAB13	VAMP2	0.91
NRAS	YWHAE	0.91
RAB14	NRAS	0.91
RAB14	YWHAH	0.91
YWHAZ	CDC25C	0.91
MTOR	YWHAG	0.91
YWHAZ	VAMP2	0.91
YWHAB	YWHAH	0.91
FOXO3	FOXO4	0.91
KRAS	YWHAH	0.909
YWHAG	LNPEP	0.909
YWHAG	CDC25B	0.909
NRAS	YWHAG	0.909
RAB14	YWHAE	0.909
YWHAG	KRAS	0.909
YWHAQ	PPP3R1	0.909
YWHAZ	LNPEP	0.909
MTOR	YWHAE	0.909
RPTOR	YWHAG	0.909
YWHAB	PPP2R2A	0.909
NRAS	YWHAH	0.908
YWHAQ	RPTOR	0.908
PPP3CC	YWHAH	0.908
YWHAB	LNPEP	0.908
YWHAE	KRAS	0.908
RAB14	RAB13	0.908
PPP2R2B	YWHAG	0.908
YWHAQ	NRAS	0.908
YWHAB	PPP3R1	0.908
RAB14	YWHAB	0.908
YWHAQ	MAP2K1	0.908
YWHAZ	PPP3R1	0.908
VAMP2	YWHAE	0.908
PPP2R2B	YWHAB	0.908
YWHAZ	ITGB4	0.907
YWHAQ	LNPEP	0.907
MAPK3	YWHAH	0.907
YWHAH	PPP3R1	0.907
YWHAZ	RPTOR	0.907
YWHAG	MAP2K2	0.907
YWHAQ	CSNK1G1	0.907
YWHAQ	CAMK4	0.907
YWHAQ	RAB14	0.907
CDC25C	YWHAH	0.907
YWHAB	RAB10	0.907
YWHAE	LNPEP	0.907
PPP2R1A	RAF1	0.907
FOXO4	YWHAB	0.907
CSNK1D	YWHAH	0.906
YWHAQ	VAMP2	0.906
YWHAE	PPP3R1	0.906
PPP2R2B	YWHAE	0.906
PPP2R2A	YWHAE	0.906
YWHAH	LNPEP	0.906
PPP2R2B	YWHAH	0.906
PPP2R2B	MAP2K1	0.906
YWHAQ	PIN1	0.906
RAF1	PIN1	0.906
MAP2K1	YWHAH	0.906
YWHAZ	PPP2R2B	0.906
PPP2R2B	MAP2K2	0.906
CSNK1A1	YWHAQ	0.906
YWHAQ	CDC25C	0.905
YWHAQ	ITGB4	0.905
CSNK1A1	YWHAB	0.905
YWHAQ	MAP2K2	0.905
YWHAZ	FOXO4	0.905
CSNK1E	YWHAB	0.905
RAB10	YWHAE	0.905
YWHAQ	RAB10	0.905
PPP3CC	YWHAG	0.905
VAMP2	YWHAH	0.905
YWHAZ	MAP2K2	0.905
YWHAB	CSNK1D	0.905
YWHAB	VAMP2	0.905
YWHAZ	CSNK1D	0.905
CSNK1E	YWHAZ	0.905
CSNK1E	YWHAE	0.905
YWHAE	CSNK1G2	0.904
YWHAZ	CSNK1G1	0.904
CSNK1G1	YWHAH	0.904
YWHAH	CDC25B	0.904
YWHAZ	CSNK1G3	0.904
PPP3CC	YWHAB	0.904
RPTOR	YWHAE	0.904
YWHAB	CSNK1G3	0.904
CSNK1G3	YWHAG	0.904
YWHAZ	CSNK1G2	0.904
PPP3CC	MEF2D	0.904
SIK1	YWHAE	0.904
YWHAB	CSNK1G1	0.904
YWHAQ	SIK3	0.904
YWHAG	CDKN1B	0.904
CSNK1G3	YWHAE	0.904
YWHAQ	CSNK1G2	0.904
CSNK1A1	YWHAE	0.904
YWHAQ	CDKN1B	0.904
YWHAG	CSNK1G1	0.904
YWHAG	RAF1	0.904
SIK3	YWHAE	0.904
YWHAZ	SIK1	0.904
RAB13	RAB10	0.904
CSNK1G3	YWHAH	0.904
SIK3	YWHAH	0.904
CSNK1A1	YWHAG	0.904
SIK3	YWHAG	0.904
YWHAB	SIK1	0.904
YWHAQ	FOXO4	0.904
YWHAB	CSNK1G2	0.904
SIK1	YWHAH	0.904
CSNK1E	CSNK1D	0.904
SIK3	YWHAB	0.904
YWHAH	ITGB4	0.904
YWHAZ	SIK3	0.904
YWHAQ	SIK1	0.904
CSNK1E	YWHAG	0.904
YWHAG	SIK1	0.904
CSNK1G1	YWHAE	0.904
CSNK1D	YWHAG	0.904
CSNK1G2	YWHAH	0.904
NRAS	KRAS	0.904
YWHAG	CSNK1G2	0.904
TP53	CSNK1G2	0.903
YWHAG	ITGB4	0.903
PPP3CC	YWHAZ	0.903
PPP3CC	YWHAE	0.903
YWHAQ	CDC25B	0.903
YWHAQ	RAF1	0.903
MAP2K2	YWHAH	0.903
FOXO4	YWHAH	0.903
PPP3CC	YWHAQ	0.903
FOXO4	YWHAE	0.903
YWHAB	RPTOR	0.903
YWHAE	ITGB4	0.902
YWHAB	ITGB4	0.902
HRAS	KRAS	0.902
CSNK1A1	YWHAH	0.902
NRAS	PPP2R1A	0.902
YWHAH	CDKN1B	0.902
HRAS	NRAS	0.902
MAPK3	MAPK1	0.902
MAP2K1	MAP2K2	0.902
RAB13	LNPEP	0.902
CSNK1G1	TP53	0.902
RAN	FOXO4	0.901
YWHAB	PIN1	0.901
CSNK1G3	TP53	0.901
RAN	FOXO3	0.901
RAB13	YWHAG	0.9
YWHAH	PIN1	0.9
YWHAB	RAB13	0.9
RAB13	YWHAH	0.9
YWHAZ	RAB13	0.9
YWHAG	PIN1	0.9
YWHAZ	PIN1	0.9
RAB13	YWHAE	0.9
YWHAE	PIN1	0.9

Gene Ontology Semantic Similarity

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#	2475 (MTOR)	207 (AKT1)	64223 (MLST8)	5515 (PPP2CA)	3265 (HRAS)	5901 (RAN)	995 (CDC25C)	7157 (TP53)	5533 (PPP3CC)	2309 (FOXO3)	5595 (MAPK3)	4893 (NRAS)	5604 (MAP2K1)	5520 (PPP2R2A)	3845 (KRAS)	1452 (CSNK1A1)	5605 (MAP2K2)	23523 (CABIN1)	5521 (PPP2R2B)	7534 (YWHAZ)	51552 (RAB14)	7532 (YWHAG)	1499 (CTNNB1)	1454 (CSNK1E)	5518 (PPP2R1A)	4303 (FOXO4)	5894 (RAF1)	7529 (YWHAB)	10890 (RAB10)	150094 (SIK1)	7514 (XPO1)	6844 (VAMP2)	7531 (YWHAE)	10971 (YWHAQ)	814 (CAMK4)	57521 (RPTOR)	7533 (YWHAH)	5300 (PIN1)	1453 (CSNK1D)	5872 (RAB13)	53944 (CSNK1G1)	1456 (CSNK1G3)	23387 (SIK3)	1455 (CSNK1G2)	1027 (CDKN1B)	5534 (PPP3R1)	5594 (MAPK1)	4209 (MEF2D)	3691 (ITGB4)	4012 (LNPEP)
2475 (MTOR)	1.00	0.71	0.46	0.46	0.45	0.45	0.47	0.57	0.49	0.53	0.77	0.50	0.73	0.44	0.50	0.78	0.69	0.26	0.46	0.63	0.43	0.56	0.59	0.77	0.47	0.60	0.81	0.62	0.43	0.65	0.46	0.57	0.60	0.57	0.38	0.72	0.58	0.56	0.74	0.44	0.71	0.45	0.66	0.71	0.59	0.50	0.78	0.51	0.52	0.43
207 (AKT1)	0.71	1.00	0.47	0.45	0.54	0.49	0.47	0.55	0.47	0.44	0.77	0.48	0.75	0.48	0.48	0.76	0.72	0.29	0.45	0.58	0.53	0.53	0.59	0.71	0.50	0.53	0.81	0.60	0.53	0.76	0.46	0.61	0.59	0.54	0.36	0.50	0.60	0.52	0.72	0.51	0.69	0.43	0.75	0.69	0.62	0.50	0.77	0.42	0.50	0.43
64223 (MLST8)	0.46	0.47	1.00	0.51	0.48	0.42	0.53	0.50	0.61	0.45	0.51	0.68	0.63	0.55	0.68	0.43	0.66	0.39	0.56	0.68	0.45	0.65	0.66	0.46	0.59	0.56	0.53	0.72	0.46	0.54	0.53	0.71	0.60	0.75	0.10	0.63	0.69	0.58	0.51	0.48	0.56	0.12	0.41	0.56	0.59	0.59	0.46	0.42	0.66	0.42
5515 (PPP2CA)	0.46	0.45	0.51	1.00	0.50	0.47	0.86	0.51	0.83	0.45	0.51	0.59	0.47	0.82	0.59	0.45	0.45	0.29	0.93	0.64	0.47	0.55	0.64	0.46	0.86	0.54	0.52	0.67	0.47	0.52	0.51	0.66	0.61	0.66	0.11	0.48	0.69	0.58	0.50	0.50	0.52	0.14	0.42	0.52	0.50	0.75	0.47	0.42	0.60	0.48
3265 (HRAS)	0.45	0.54	0.48	0.50	1.00	0.70	0.51	0.54	0.53	0.45	0.48	0.55	0.48	0.46	0.55	0.42	0.44	0.28	0.50	0.63	0.94	0.54	0.64	0.45	0.51	0.54	0.49	0.65	0.90	0.66	0.48	0.65	0.58	0.61	0.09	0.47	0.62	0.64	0.47	0.96	0.48	0.11	0.59	0.48	0.48	0.55	0.45	0.41	0.57	0.44
5901 (RAN)	0.45	0.49	0.42	0.47	0.70	1.00	0.44	0.62	0.45	0.51	0.43	0.49	0.42	0.42	0.49	0.40	0.41	0.28	0.43	0.64	0.69	0.56	0.71	0.52	0.48	0.54	0.44	0.57	0.69	0.61	0.54	0.54	0.62	0.49	0.08	0.49	0.58	0.54	0.46	0.67	0.42	0.10	0.56	0.42	0.47	0.51	0.42	0.41	0.48	0.44
995 (CDC25C)	0.47	0.47	0.53	0.86	0.51	0.44	1.00	0.52	0.77	0.50	0.51	0.59	0.48	0.75	0.59	0.47	0.47	0.30	0.83	0.70	0.49	0.61	0.65	0.47	0.74	0.55	0.54	0.69	0.49	0.59	0.52	0.65	0.59	0.65	0.10	0.54	0.66	0.62	0.51	0.51	0.53	0.13	0.43	0.53	0.56	0.73	0.48	0.43	0.60	0.49
7157 (TP53)	0.57	0.55	0.50	0.51	0.54	0.62	0.52	1.00	0.51	0.75	0.52	0.54	0.50	0.49	0.54	0.48	0.49	0.30	0.50	0.65	0.53	0.59	0.66	0.54	0.52	0.76	0.54	0.60	0.53	0.59	0.50	0.55	0.64	0.55	0.07	0.61	0.59	0.53	0.50	0.53	0.50	0.09	0.54	0.50	0.57	0.55	0.51	0.71	0.52	0.52
5533 (PPP3CC)	0.49	0.47	0.61	0.83	0.53	0.45	0.77	0.51	1.00	0.48	0.55	0.70	0.50	0.76	0.70	0.49	0.49	0.35	0.88	0.69	0.51	0.61	0.67	0.51	0.75	0.58	0.56	0.72	0.50	0.57	0.58	0.75	0.61	0.76	0.11	0.51	0.69	0.61	0.56	0.54	0.61	0.13	0.46	0.61	0.53	0.80	0.50	0.45	0.68	0.48
2309 (FOXO3)	0.53	0.44	0.45	0.45	0.45	0.51	0.50	0.75	0.48	1.00	0.45	0.50	0.44	0.43	0.50	0.42	0.43	0.28	0.45	0.68	0.44	0.60	0.63	0.52	0.47	0.88	0.47	0.57	0.44	0.53	0.46	0.56	0.59	0.52	0.08	0.59	0.56	0.55	0.45	0.44	0.45	0.10	0.42	0.45	0.51	0.49	0.44	0.78	0.51	0.41
5595 (MAPK3)	0.77	0.77	0.51	0.51	0.48	0.43	0.51	0.52	0.55	0.45	1.00	0.57	0.79	0.48	0.57	0.91	0.77	0.29	0.52	0.64	0.46	0.57	0.64	0.83	0.52	0.57	0.94	0.68	0.46	0.73	0.51	0.63	0.60	0.66	0.52	0.48	0.66	0.57	0.86	0.48	0.87	0.59	0.75	0.87	0.67	0.60	0.99	0.43	0.58	0.45
4893 (NRAS)	0.50	0.48	0.68	0.59	0.55	0.49	0.59	0.54	0.70	0.50	0.57	1.00	0.52	0.58	1.00	0.51	0.51	0.45	0.68	0.73	0.52	0.64	0.71	0.54	0.61	0.60	0.58	0.76	0.52	0.59	0.62	0.75	0.62	0.84	0.12	0.59	0.72	0.63	0.59	0.57	0.68	0.14	0.48	0.68	0.62	0.64	0.52	0.46	0.72	0.47
5604 (MAP2K1)	0.73	0.75	0.63	0.47	0.48	0.42	0.48	0.50	0.50	0.44	0.79	0.52	1.00	0.48	0.52	0.84	0.95	0.29	0.48	0.58	0.44	0.54	0.61	0.81	0.51	0.51	0.84	0.60	0.44	0.72	0.48	0.59	0.57	0.59	0.46	0.56	0.59	0.54	0.83	0.45	0.81	0.56	0.73	0.81	0.69	0.52	0.80	0.42	0.54	0.43
5520 (PPP2R2A)	0.44	0.48	0.55	0.82	0.46	0.42	0.75	0.49	0.76	0.43	0.48	0.58	0.48	1.00	0.58	0.40	0.46	0.52	0.84	0.64	0.44	0.57	0.64	0.42	0.93	0.53	0.49	0.67	0.44	0.51	0.49	0.66	0.60	0.66	0.11	0.51	0.66	0.56	0.47	0.45	0.49	0.13	0.38	0.49	0.52	0.70	0.44	0.40	0.60	0.43
3845 (KRAS)	0.50	0.48	0.68	0.59	0.55	0.49	0.59	0.54	0.70	0.50	0.57	1.00	0.52	0.58	1.00	0.51	0.51	0.45	0.68	0.73	0.52	0.64	0.71	0.54	0.61	0.60	0.58	0.76	0.52	0.59	0.62	0.75	0.62	0.84	0.12	0.59	0.72	0.63	0.59	0.57	0.68	0.14	0.48	0.68	0.62	0.64	0.52	0.46	0.72	0.47
1452 (CSNK1A1)	0.78	0.76	0.43	0.45	0.42	0.40	0.47	0.48	0.49	0.42	0.91	0.51	0.84	0.40	0.51	1.00	0.80	0.25	0.44	0.60	0.40	0.50	0.61	0.89	0.47	0.50	0.96	0.62	0.40	0.75	0.44	0.62	0.55	0.58	0.69	0.45	0.60	0.55	0.93	0.40	0.93	0.82	0.78	0.93	0.63	0.52	0.91	0.38	0.55	0.40
5605 (MAP2K2)	0.69	0.72	0.66	0.45	0.44	0.41	0.47	0.49	0.49	0.43	0.77	0.51	0.95	0.46	0.51	0.80	1.00	0.29	0.46	0.58	0.42	0.54	0.60	0.77	0.50	0.51	0.80	0.62	0.43	0.69	0.47	0.60	0.57	0.56	0.47	0.56	0.60	0.53	0.80	0.43	0.78	0.54	0.69	0.78	0.67	0.53	0.78	0.41	0.54	0.41
23523 (CABIN1)	0.26	0.29	0.39	0.29	0.28	0.28	0.30	0.30	0.35	0.28	0.29	0.45	0.29	0.52	0.45	0.25	0.29	1.00	0.33	0.39	0.26	0.38	0.40	0.27	0.49	0.32	0.30	0.41	0.27	0.31	0.31	0.40	0.38	0.43	0.06	0.34	0.40	0.33	0.30	0.28	0.33	0.08	0.24	0.33	0.37	0.33	0.27	0.24	0.42	0.24
5521 (PPP2R2B)	0.46	0.45	0.56	0.93	0.50	0.43	0.83	0.50	0.88	0.45	0.52	0.68	0.48	0.84	0.68	0.44	0.46	0.33	1.00	0.68	0.47	0.58	0.66	0.46	0.80	0.56	0.53	0.72	0.47	0.54	0.54	0.71	0.60	0.75	0.11	0.49	0.68	0.60	0.52	0.51	0.56	0.14	0.41	0.56	0.51	0.76	0.47	0.42	0.66	0.46
7534 (YWHAZ)	0.63	0.58	0.68	0.64	0.63	0.64	0.70	0.65	0.69	0.68	0.64	0.73	0.58	0.64	0.73	0.60	0.58	0.39	0.68	1.00	0.61	0.82	0.77	0.72	0.65	0.75	0.67	0.81	0.62	0.70	0.66	0.73	0.79	0.79	0.09	0.66	0.77	0.68	0.69	0.64	0.68	0.11	0.58	0.68	0.64	0.66	0.61	0.57	0.71	0.57
51552 (RAB14)	0.43	0.53	0.45	0.47	0.94	0.69	0.49	0.53	0.51	0.44	0.46	0.52	0.44	0.44	0.52	0.40	0.42	0.26	0.47	0.61	1.00	0.52	0.61	0.43	0.49	0.52	0.47	0.64	0.95	0.64	0.45	0.63	0.57	0.59	0.08	0.46	0.60	0.63	0.45	0.94	0.45	0.10	0.57	0.45	0.47	0.53	0.43	0.40	0.55	0.42
7532 (YWHAG)	0.56	0.53	0.65	0.55	0.54	0.56	0.61	0.59	0.61	0.60	0.57	0.64	0.54	0.57	0.64	0.50	0.54	0.38	0.58	0.82	0.52	1.00	0.66	0.64	0.59	0.67	0.59	0.72	0.52	0.61	0.56	0.68	0.68	0.73	0.09	0.70	0.74	0.62	0.55	0.54	0.58	0.10	0.49	0.58	0.70	0.59	0.53	0.49	0.64	0.48
1499 (CTNNB1)	0.59	0.59	0.66	0.64	0.64	0.71	0.65	0.66	0.67	0.63	0.64	0.71	0.61	0.64	0.71	0.61	0.60	0.40	0.66	0.77	0.61	0.66	1.00	0.62	0.64	0.68	0.66	0.75	0.62	0.66	0.65	0.69	0.69	0.70	0.08	0.63	0.76	0.65	0.66	0.63	0.66	0.10	0.60	0.66	0.67	0.67	0.62	0.60	0.68	0.59
1454 (CSNK1E)	0.77	0.71	0.46	0.46	0.45	0.52	0.47	0.54	0.51	0.52	0.83	0.54	0.81	0.42	0.54	0.89	0.77	0.27	0.46	0.72	0.43	0.64	0.62	1.00	0.48	0.60	0.88	0.64	0.44	0.72	0.46	0.63	0.63	0.61	0.60	0.51	0.61	0.55	0.88	0.43	0.88	0.70	0.75	0.88	0.62	0.53	0.83	0.42	0.57	0.40
5518 (PPP2R1A)	0.47	0.50	0.59	0.86	0.51	0.48	0.74	0.52	0.75	0.47	0.52	0.61	0.51	0.93	0.61	0.47	0.50	0.49	0.80	0.65	0.49	0.59	0.64	0.48	1.00	0.56	0.53	0.67	0.49	0.54	0.54	0.67	0.64	0.67	0.10	0.53	0.71	0.58	0.52	0.51	0.55	0.12	0.45	0.55	0.55	0.70	0.49	0.44	0.62	0.48
4303 (FOXO4)	0.60	0.53	0.56	0.54	0.54	0.54	0.55	0.76	0.58	0.88	0.57	0.60	0.51	0.53	0.60	0.50	0.51	0.32	0.56	0.75	0.52	0.67	0.68	0.60	0.56	1.00	0.59	0.70	0.52	0.57	0.56	0.64	0.67	0.66	0.10	0.60	0.67	0.60	0.54	0.54	0.56	0.11	0.50	0.56	0.54	0.59	0.54	0.81	0.61	0.49
5894 (RAF1)	0.81	0.81	0.53	0.52	0.49	0.44	0.54	0.54	0.56	0.47	0.94	0.58	0.84	0.49	0.58	0.96	0.80	0.30	0.53	0.67	0.47	0.59	0.66	0.88	0.53	0.59	1.00	0.71	0.47	0.77	0.52	0.64	0.62	0.68	0.54	0.50	0.68	0.59	0.91	0.49	0.90	0.64	0.78	0.90	0.67	0.58	0.94	0.45	0.60	0.47
7529 (YWHAB)	0.62	0.60	0.72	0.67	0.65	0.57	0.69	0.60	0.72	0.57	0.68	0.76	0.60	0.67	0.76	0.62	0.62	0.41	0.72	0.81	0.64	0.72	0.75	0.64	0.67	0.70	0.71	1.00	0.64	0.67	0.69	0.75	0.81	0.82	0.09	0.60	0.80	0.77	0.72	0.67	0.72	0.11	0.61	0.72	0.63	0.72	0.64	0.60	0.73	0.59
10890 (RAB10)	0.43	0.53	0.46	0.47	0.90	0.69	0.49	0.53	0.50	0.44	0.46	0.52	0.44	0.44	0.52	0.40	0.43	0.27	0.47	0.62	0.95	0.52	0.62	0.44	0.49	0.52	0.47	0.64	1.00	0.63	0.45	0.62	0.57	0.57	0.08	0.46	0.59	0.62	0.48	0.89	0.46	0.10	0.56	0.46	0.47	0.53	0.44	0.40	0.55	0.43
150094 (SIK1)	0.65	0.76	0.54	0.52	0.66	0.61	0.59	0.59	0.57	0.53	0.73	0.59	0.72	0.51	0.59	0.75	0.69	0.31	0.54	0.70	0.64	0.61	0.66	0.72	0.54	0.57	0.77	0.67	0.63	1.00	0.53	0.65	0.59	0.64	0.34	0.56	0.64	0.61	0.75	0.63	0.73	0.38	0.91	0.73	0.64	0.62	0.75	0.45	0.60	0.51
7514 (XPO1)	0.46	0.46	0.53	0.51	0.48	0.54	0.52	0.50	0.58	0.46	0.51	0.62	0.48	0.49	0.62	0.44	0.47	0.31	0.54	0.66	0.45	0.56	0.65	0.46	0.54	0.56	0.52	0.69	0.45	0.53	1.00	0.68	0.60	0.69	0.13	0.49	0.66	0.57	0.51	0.47	0.54	0.15	0.42	0.54	0.51	0.57	0.47	0.43	0.62	0.43
6844 (VAMP2)	0.57	0.61	0.71	0.66	0.65	0.54	0.65	0.55	0.75	0.56	0.63	0.75	0.59	0.66	0.75	0.62	0.60	0.40	0.71	0.73	0.63	0.68	0.69	0.63	0.67	0.64	0.64	0.75	0.62	0.65	0.68	1.00	0.65	0.78	0.10	0.59	0.72	0.66	0.66	0.67	0.71	0.11	0.60	0.71	0.61	0.70	0.60	0.55	0.72	0.58
7531 (YWHAE)	0.60	0.59	0.60	0.61	0.58	0.62	0.59	0.64	0.61	0.59	0.60	0.62	0.57	0.60	0.62	0.55	0.57	0.38	0.60	0.79	0.57	0.68	0.69	0.63	0.64	0.67	0.62	0.81	0.57	0.59	0.60	0.65	1.00	0.67	0.09	0.59	0.78	0.67	0.61	0.58	0.60	0.10	0.55	0.60	0.58	0.61	0.58	0.56	0.63	0.54
10971 (YWHAQ)	0.57	0.54	0.75	0.66	0.61	0.49	0.65	0.55	0.76	0.52	0.66	0.84	0.59	0.66	0.84	0.58	0.56	0.43	0.75	0.79	0.59	0.73	0.70	0.61	0.67	0.66	0.68	0.82	0.57	0.64	0.69	0.78	0.67	1.00	0.11	0.56	0.78	0.66	0.66	0.65	0.75	0.13	0.55	0.75	0.59	0.68	0.61	0.51	0.76	0.54
814 (CAMK4)	0.38	0.36	0.10	0.11	0.09	0.08	0.10	0.07	0.11	0.08	0.52	0.12	0.46	0.11	0.12	0.69	0.47	0.06	0.11	0.09	0.08	0.09	0.08	0.60	0.10	0.10	0.54	0.09	0.08	0.34	0.13	0.10	0.09	0.11	1.00	0.08	0.09	0.11	0.60	0.10	0.68	0.85	0.50	0.68	0.24	0.09	0.55	0.08	0.09	0.11
57521 (RPTOR)	0.72	0.50	0.63	0.48	0.47	0.49	0.54	0.61	0.51	0.59	0.48	0.59	0.56	0.51	0.59	0.45	0.56	0.34	0.49	0.66	0.46	0.70	0.63	0.51	0.53	0.60	0.50	0.60	0.46	0.56	0.49	0.59	0.59	0.56	0.08	1.00	0.60	0.56	0.48	0.47	0.49	0.09	0.44	0.49	0.69	0.52	0.46	0.52	0.54	0.44
7533 (YWHAH)	0.58	0.60	0.69	0.69	0.62	0.58	0.66	0.59	0.69	0.56	0.66	0.72	0.59	0.66	0.72	0.60	0.60	0.40	0.68	0.77	0.60	0.74	0.76	0.61	0.71	0.67	0.68	0.80	0.59	0.64	0.66	0.72	0.78	0.78	0.09	0.60	1.00	0.65	0.64	0.64	0.68	0.11	0.58	0.68	0.62	0.69	0.62	0.56	0.71	0.57
5300 (PIN1)	0.56	0.52	0.58	0.58	0.64	0.54	0.62	0.53	0.61	0.55	0.57	0.63	0.54	0.56	0.63	0.55	0.53	0.33	0.60	0.68	0.63	0.62	0.65	0.55	0.58	0.60	0.59	0.77	0.62	0.61	0.57	0.66	0.67	0.66	0.11	0.56	0.65	1.00	0.57	0.66	0.59	0.13	0.52	0.59	0.57	0.60	0.55	0.49	0.63	0.53
1453 (CSNK1D)	0.74	0.72	0.51	0.50	0.47	0.46	0.51	0.50	0.56	0.45	0.86	0.59	0.83	0.47	0.59	0.93	0.80	0.30	0.52	0.69	0.45	0.55	0.66	0.88	0.52	0.54	0.91	0.72	0.48	0.75	0.51	0.66	0.61	0.66	0.60	0.48	0.64	0.57	1.00	0.46	0.93	0.71	0.78	0.93	0.64	0.56	0.86	0.42	0.61	0.43
5872 (RAB13)	0.44	0.51	0.48	0.50	0.96	0.67	0.51	0.53	0.54	0.44	0.48	0.57	0.45	0.45	0.57	0.40	0.43	0.28	0.51	0.64	0.94	0.54	0.63	0.43	0.51	0.54	0.49	0.67	0.89	0.63	0.47	0.67	0.58	0.65	0.10	0.47	0.64	0.66	0.46	1.00	0.48	0.12	0.54	0.48	0.48	0.56	0.44	0.40	0.60	0.43
53944 (CSNK1G1)	0.71	0.69	0.56	0.52	0.48	0.42	0.53	0.50	0.61	0.45	0.87	0.68	0.81	0.49	0.68	0.93	0.78	0.33	0.56	0.68	0.45	0.58	0.66	0.88	0.55	0.56	0.90	0.72	0.46	0.73	0.54	0.71	0.60	0.75	0.68	0.49	0.68	0.59	0.93	0.48	1.00	0.76	0.76	1.00	0.63	0.59	0.87	0.42	0.66	0.42
1456 (CSNK1G3)	0.45	0.43	0.12	0.14	0.11	0.10	0.13	0.09	0.13	0.10	0.59	0.14	0.56	0.13	0.14	0.82	0.54	0.08	0.14	0.11	0.10	0.10	0.10	0.70	0.12	0.11	0.64	0.11	0.10	0.38	0.15	0.11	0.10	0.13	0.85	0.09	0.11	0.13	0.71	0.12	0.76	1.00	0.58	0.76	0.27	0.11	0.63	0.10	0.11	0.14
23387 (SIK3)	0.66	0.75	0.41	0.42	0.59	0.56	0.43	0.54	0.46	0.42	0.75	0.48	0.73	0.38	0.48	0.78	0.69	0.24	0.41	0.58	0.57	0.49	0.60	0.75	0.45	0.50	0.78	0.61	0.56	0.91	0.42	0.60	0.55	0.55	0.50	0.44	0.58	0.52	0.78	0.54	0.76	0.58	1.00	0.76	0.58	0.56	0.76	0.37	0.52	0.42
1455 (CSNK1G2)	0.71	0.69	0.56	0.52	0.48	0.42	0.53	0.50	0.61	0.45	0.87	0.68	0.81	0.49	0.68	0.93	0.78	0.33	0.56	0.68	0.45	0.58	0.66	0.88	0.55	0.56	0.90	0.72	0.46	0.73	0.54	0.71	0.60	0.75	0.68	0.49	0.68	0.59	0.93	0.48	1.00	0.76	0.76	1.00	0.63	0.59	0.87	0.42	0.66	0.42
1027 (CDKN1B)	0.59	0.62	0.59	0.50	0.48	0.47	0.56	0.57	0.53	0.51	0.67	0.62	0.69	0.52	0.62	0.63	0.67	0.37	0.51	0.64	0.47	0.70	0.67	0.62	0.55	0.54	0.67	0.63	0.47	0.64	0.51	0.61	0.58	0.59	0.24	0.69	0.62	0.57	0.64	0.48	0.63	0.27	0.58	0.63	1.00	0.56	0.68	0.45	0.56	0.45
5534 (PPP3R1)	0.50	0.50	0.59	0.75	0.55	0.51	0.73	0.55	0.80	0.49	0.60	0.64	0.52	0.70	0.64	0.52	0.53	0.33	0.76	0.66	0.53	0.59	0.67	0.53	0.70	0.59	0.58	0.72	0.53	0.62	0.57	0.70	0.61	0.68	0.09	0.52	0.69	0.60	0.56	0.56	0.59	0.11	0.56	0.59	0.56	1.00	0.56	0.48	0.64	0.61
5594 (MAPK1)	0.78	0.77	0.46	0.47	0.45	0.42	0.48	0.51	0.50	0.44	0.99	0.52	0.80	0.44	0.52	0.91	0.78	0.27	0.47	0.61	0.43	0.53	0.62	0.83	0.49	0.54	0.94	0.64	0.44	0.75	0.47	0.60	0.58	0.61	0.55	0.46	0.62	0.55	0.86	0.44	0.87	0.63	0.76	0.87	0.68	0.56	1.00	0.41	0.55	0.43
4209 (MEF2D)	0.51	0.42	0.42	0.42	0.41	0.41	0.43	0.71	0.45	0.78	0.43	0.46	0.42	0.40	0.46	0.38	0.41	0.24	0.42	0.57	0.40	0.49	0.60	0.42	0.44	0.81	0.45	0.60	0.40	0.45	0.43	0.55	0.56	0.51	0.08	0.52	0.56	0.49	0.42	0.40	0.42	0.10	0.37	0.42	0.45	0.48	0.41	1.00	0.50	0.38
3691 (ITGB4)	0.52	0.50	0.66	0.60	0.57	0.48	0.60	0.52	0.68	0.51	0.58	0.72	0.54	0.60	0.72	0.55	0.54	0.42	0.66	0.71	0.55	0.64	0.68	0.57	0.62	0.61	0.60	0.73	0.55	0.60	0.62	0.72	0.63	0.76	0.09	0.54	0.71	0.63	0.61	0.60	0.66	0.11	0.52	0.66	0.56	0.64	0.55	0.50	1.00	0.52
4012 (LNPEP)	0.43	0.43	0.42	0.48	0.44	0.44	0.49	0.52	0.48	0.41	0.45	0.47	0.43	0.43	0.47	0.40	0.41	0.24	0.46	0.57	0.42	0.48	0.59	0.40	0.48	0.49	0.47	0.59	0.43	0.51	0.43	0.58	0.54	0.54	0.11	0.44	0.57	0.53	0.43	0.43	0.42	0.14	0.42	0.42	0.45	0.61	0.43	0.38	0.52	1.00

Association with High Altitude

Protein Official symbol	Source Organism	Tissue of Expression	Level of hypoxia	Altitude	Duration of experiment	Level of expression	Fold change	Experiment details	geographical location	ethnicity of the patients	Control group	Control (Fold change)	Reference (PMID)
YWHAQ	Human	Blood	-	3600 m	Native	upregulated	-	TMT-based proteomic analysis/LC-MS	Central Asia	Tibetans	-	High altitude native vs. low Lander	30908922

Association with TF

TF	TF Entrez	Gene	Gene Entrez	Type	PMID	Database
RFX5	5993	YWHAQ	10971	proximal_filtered	22955619	TRANSFAC
NR3C1	2908	YWHAQ	10971	proximal_filtered	22955619	TRANSFAC
PGR	5241	YWHAQ	10971	Unknown	10816575	TRUSST
ESR1	2099	YWHAQ	10971	Unknown	10816575	TRUSST

Association with miRNA

miRTarBase ID	miRNA	Species (miRNA)	Protein Official Symbol	Human Entrez ID	Species (Target Gene)	Experiments	Support Type	References (PMID)
MIRT001321	hsa-miR-1-3p	Homo sapiens	YWHAQ	10971	Homo sapiens	pSILAC//Proteomics;Other	Functional MTI (Weak)	18668040
MIRT024964	hsa-miR-214-3p	Homo sapiens	YWHAQ	10971	Homo sapiens	Microarray;Other	Functional MTI (Weak)	19859982
MIRT035800	hsa-miR-1910-5p	Homo sapiens	YWHAQ	10971	Homo sapiens	CLASH	Functional MTI (Weak)	23622248
MIRT041385	hsa-miR-193b-3p	Homo sapiens	YWHAQ	10971	Homo sapiens	CLASH	Functional MTI (Weak)	23622248
MIRT042441	hsa-miR-424-5p	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT042441	hsa-miR-424-5p	Homo sapiens	YWHAQ	10971	Homo sapiens	CLASH	Functional MTI (Weak)	23622248
MIRT042637	hsa-miR-423-3p	Homo sapiens	YWHAQ	10971	Homo sapiens	CLASH	Functional MTI (Weak)	23622248
MIRT043806	hsa-miR-328-3p	Homo sapiens	YWHAQ	10971	Homo sapiens	CLASH	Functional MTI (Weak)	23622248
MIRT048886	hsa-miR-93-5p	Homo sapiens	YWHAQ	10971	Homo sapiens	CLASH	Functional MTI (Weak)	23622248
MIRT049225	hsa-miR-92a-3p	Homo sapiens	YWHAQ	10971	Homo sapiens	CLASH	Functional MTI (Weak)	23622248
MIRT051526	hsa-let-7e-5p	Homo sapiens	YWHAQ	10971	Homo sapiens	CLASH	Functional MTI (Weak)	23622248
MIRT051373	hsa-let-7f-5p	Homo sapiens	YWHAQ	10971	Homo sapiens	CLASH	Functional MTI (Weak)	23622248
MIRT510499	hsa-miR-4683	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT510498	hsa-miR-526b-5p	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT510496	hsa-miR-1270	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT510494	hsa-miR-620	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT510497	hsa-miR-6505-5p	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT510500	hsa-miR-4635	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT510495	hsa-miR-578	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT510503	hsa-miR-576-3p	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT510501	hsa-miR-3691-3p	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT510502	hsa-miR-511-3p	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT545967	hsa-miR-651-3p	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT545974	hsa-miR-16-5p	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT545970	hsa-miR-4311	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT545965	hsa-miR-4496	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT545973	hsa-miR-15a-5p	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT545972	hsa-miR-15b-5p	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT545976	hsa-miR-195-5p	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT545975	hsa-miR-497-5p	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT545966	hsa-miR-5586-3p	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT545971	hsa-miR-6838-5p	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT545968	hsa-miR-583	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT545969	hsa-miR-1276	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT545963	hsa-miR-302a-5p	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT545964	hsa-miR-545-3p	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT571554	hsa-miR-4717-3p	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT571556	hsa-miR-4762-5p	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT571553	hsa-miR-342-3p	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT571547	hsa-miR-7702	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT571551	hsa-miR-3148	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT571555	hsa-miR-4719	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT571561	hsa-miR-8054	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT571552	hsa-miR-20a-3p	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT571563	hsa-miR-548av-5p	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT571550	hsa-miR-6124	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT571548	hsa-miR-5011-3p	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT571558	hsa-miR-890	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT571560	hsa-miR-548at-5p	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT571564	hsa-miR-548n	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT571559	hsa-miR-561-3p	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT571557	hsa-miR-3688-3p	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT571549	hsa-miR-151a-3p	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT571562	hsa-miR-548k	Homo sapiens	YWHAQ	10971	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350

Gene Ontology

ID	GO ID	GO Term	GO Type
10971	GO:0061024	membrane organization	GOTERM_BP_DIRECT
10971	GO:0044325	ion channel binding	GOTERM_MF_DIRECT
10971	GO:0019904	protein domain specific binding	GOTERM_MF_DIRECT
10971	GO:0005515	protein binding	GOTERM_MF_DIRECT
10971	GO:0070062	extracellular exosome	GOTERM_CC_DIRECT
10971	GO:0016020	membrane	GOTERM_CC_DIRECT
10971	GO:0043234	protein complex	GOTERM_CC_DIRECT
10971	GO:0007264	small GTPase mediated signal transduction	GOTERM_BP_DIRECT
10971	GO:1900740	positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	GOTERM_BP_DIRECT
10971	GO:0071889	14-3-3 protein binding	GOTERM_MF_DIRECT
10971	GO:0034766	negative regulation of ion transmembrane transport	GOTERM_BP_DIRECT
10971	GO:0005737	cytoplasm	GOTERM_CC_DIRECT
10971	GO:0008022	protein C-terminus binding	GOTERM_MF_DIRECT
10971	GO:0030659	cytoplasmic vesicle membrane	GOTERM_CC_DIRECT
10971	GO:0005739	mitochondrion	GOTERM_CC_DIRECT
10971	GO:0005829	cytosol	GOTERM_CC_DIRECT
10971	GO:0006605	protein targeting	GOTERM_BP_DIRECT
10971	GO:0021762	substantia nigra development	GOTERM_BP_DIRECT
10971	GO:0047485	protein N-terminus binding	GOTERM_MF_DIRECT
10971	GO:0045892	negative regulation of transcription	GOTERM_BP_DIRECT
10971	GO:0005925	focal adhesion	GOTERM_CC_DIRECT

Pathways

Human Entrez ID	KEGG ID	KEGG Term
10971	hsa04110	Cell cycle
10971	hsa04114	Oocyte meiosis
10971	hsa04151	PI3K-Akt signaling pathway
10971	hsa04390	Hippo signaling pathway
10971	hsa05161	Hepatitis B
10971	hsa05203	Viral carcinogenesis

Association with Disease

Protein Official Symbol	Human Entrez ID	Disease Name	Disease Id	Disease Semantic Type	Semantic score	DSI	DPI	Disease Type
YWHAQ	10971	Osteoarthrosis Deformans	C0086743	Disease or Syndrome	0.3	0.72	0.379	disease
YWHAQ	10971	Degenerative polyarthritis	C0029408	Disease or Syndrome	0.3	0.72	0.379	disease

Association with Drug

Protein Official Symbol	Human Entrez ID	drug_claim_primary_name	drug_name	drug_chembl_id	interaction_types