ALTITUDEOMICSDB

14-3-3 protein eta

AltitudeomicsDB

Protein Official symbol	YWHAH
Aliases	YWHAH YWHA1
Chromosomal Location	22
Length	246
Uniprot ID	Q04917
EC number	None
Protein family Information(Pfam)	PF00244;
PDB id	2C63;2C74;
InterPro ID	IPR000308;IPR023409;IPR036815;IPR023410;
dbSNP	None

Protein Protein Interaction

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AltitudeomicsDB

Protein 1	Protein 2	Combine Score
MTOR	RPTOR	0.999
CDK1	CCNB1	0.999
AKT1	FOXO3	0.998
CDC25C	CCNB1	0.998
CDK1	CDC25C	0.998
CHEK2	CDC25C	0.997
IGF1	IGF1R	0.997
CHEK2	TP53	0.997
AKT1	MTOR	0.997
AKT1	TSC2	0.997
MTOR	TSC2	0.996
CHEK1	CDC25C	0.996
MLST8	RPTOR	0.996
PPP2CA	PPP2R1A	0.995
AKT1	CTNNB1	0.995
SOS1	GRB2	0.995
MLST8	MTOR	0.994
AKT1	AKT1S1	0.994
CHEK1	TP53	0.993
AKT1	TP53	0.993
AKT1	FOXO1	0.993
RPTOR	TSC2	0.993
AKT1S1	RPTOR	0.992
HRAS	RAF1	0.989
MLST8	AKT1S1	0.988
RAN	XPO1	0.988
MLST8	TSC2	0.987
CDC25C	TP53	0.987
HRAS	MAP2K1	0.986
AKT1S1	MTOR	0.986
AKT1	GRB2	0.986
AKT1	RPTOR	0.986
PPP2CA	PPP2R2A	0.985
GRB2	MAPK3	0.984
GRB2	MAPK1	0.982
IGF1	MAPK3	0.981
HRAS	MAPK3	0.981
PPP3CC	PPP3R1	0.98
MAP2K1	KRAS	0.979
MAPK3	KRAS	0.979
HRAS	MAPK1	0.979
NRAS	MAP2K1	0.979
NRAS	RAF1	0.978
GRB2	MAP2K1	0.978
PPP2R2A	PPP2R1A	0.977
KSR1	MAP2K1	0.976
HRAS	SOS1	0.976
HRAS	GRB2	0.976
SOS1	MAP2K1	0.976
KRAS	RAF1	0.975
NRAS	MAPK3	0.973
AKT1	PPP2CA	0.973
SOS1	KRAS	0.973
KRAS	MAPK1	0.973
MLST8	AKT1	0.972
TP53	MAPK1	0.971
GRB2	KRAS	0.971
NRAS	MAPK1	0.97
MAPK3	TSC2	0.969
HRAS	IGF1R	0.968
KSR1	MAPK3	0.967
KSR1	MAPK1	0.967
GRB2	NRAS	0.965
SOS1	MAPK3	0.965
FOXO1	CTNNB1	0.965
FOXO3	CTNNB1	0.964
SOS1	NRAS	0.964
SOS1	MAPK1	0.963
FOXO3	YWHAZ	0.962
IGF1	MAPK1	0.962
PPP2R2B	PPP2R1A	0.961
AKT1S1	YWHAH	0.96
YWHAB	TSC2	0.96
TSC2	MAPK1	0.96
GRB2	IGF1R	0.959
FOXO3	MAPK1	0.958
HRAS	IGF1	0.958
AKT1	PPP2R1A	0.957
PPP2CA	PPP2R2B	0.957
AKT1	SOS1	0.956
GRB2	IGF1	0.955
YWHAZ	CTNNB1	0.955
PPP2CA	YWHAQ	0.953
YWHAG	YWHAE	0.952
RAB14	YWHAG	0.952
HRAS	TP53	0.952
RAB14	LNPEP	0.951
HRAS	RASGRF1	0.951
CDC25C	YWHAG	0.951
CHEK1	CCNB1	0.951
HRAS	KSR1	0.951
XPO1	CDK1	0.95
CSNK1E	CTNNB1	0.95
PPP2R1A	KRAS	0.95
CTNNB1	PPP2R1A	0.95
CTNNB1	IGF1	0.949
AKT1	YWHAZ	0.949
AKT1	IGF1	0.948
RAF1	YWHAH	0.948
HRAS	PPP2R1A	0.948
MAP2K1	MAPK3	0.948
MAP2K1	MAPK1	0.947
CTNNB1	IGF1R	0.947
GRB2	MTOR	0.946
TP53	MAPK3	0.946
CDK1	CSNK1D	0.945
RASGRF1	KRAS	0.944
PPP2CA	MAPK3	0.944
PPP2R1A	TP53	0.943
KSR1	NRAS	0.942
MAP2K1	RAF1	0.942
XPO1	CCNB1	0.942
YWHAB	RAF1	0.942
FOXO3	XPO1	0.942
PPP2CA	CDK1	0.941
AKT1	YWHAB	0.94
KSR1	KRAS	0.94
RAN	YWHAQ	0.94
RAN	YWHAE	0.94
RAB10	LNPEP	0.939
AKT1	YWHAQ	0.939
FOXO3	MAPK3	0.939
IGF1	RAF1	0.939
PPP2CA	YWHAZ	0.939
PPP2CA	MAP2K1	0.938
RAF1	MAPK1	0.938
VAMP2	LNPEP	0.937
AKT1	YWHAE	0.937
YWHAZ	TP53	0.937
PPP2CA	MAPK1	0.937
XPO1	PPP2R1A	0.937
XPO1	FOXO1	0.936
AKT1	RAF1	0.936
RAN	YWHAZ	0.936
PPP2CA	MTOR	0.936
MAPK3	RAF1	0.936
PPP2CA	YWHAB	0.935
CTNNB1	CSNK1D	0.935
YWHAZ	YWHAH	0.935
CHEK2	CCNB1	0.935
XPO1	YWHAQ	0.934
PPP2CA	TP53	0.933
YWHAZ	RAF1	0.933
RAN	YWHAB	0.933
IGF1R	KRAS	0.933
PPP2CA	YWHAG	0.933
CDK1	PPP2R2A	0.932
PPP2CA	YWHAH	0.932
YWHAB	PPP2R1A	0.932
YWHAZ	RAB14	0.932
PPP2CA	CCNB1	0.932
FOXO1	MAPK1	0.931
PPP2R1A	MAPK3	0.931
YWHAB	YWHAE	0.931
AKT1	YWHAH	0.931
VAMP2	RAB10	0.93
IGF1R	MAPK3	0.93
AKT1	YWHAG	0.93
KSR1	RAF1	0.93
FOXO3	YWHAE	0.93
TP53	YWHAE	0.929
FOXO3	YWHAB	0.929
XPO1	CTNNB1	0.929
YWHAZ	MAPK1	0.929
YWHAQ	MAPK1	0.929
YWHAQ	YWHAG	0.928
YWHAB	CDC25C	0.928
YWHAQ	PPP2R1A	0.928
CDC25C	YWHAE	0.928
MAP2K1	YWHAE	0.928
AKT1	LNPEP	0.927
HRAS	YWHAZ	0.926
PPP2R1A	MAPK1	0.926
YWHAZ	TSC2	0.926
IGF1R	MAPK1	0.926
YWHAE	MAPK1	0.926
YWHAQ	PPP2R2A	0.925
YWHAG	MAPK1	0.925
YWHAB	MTOR	0.925
PPP2R2A	CCNB1	0.925
YWHAQ	YWHAE	0.925
YWHAZ	MTOR	0.924
CDK1	MAP2K1	0.924
TP53	KRAS	0.924
FOXO3	YWHAQ	0.924
RAN	YWHAH	0.924
HRAS	YWHAB	0.924
PPP2R1A	CCNB1	0.924
SOS1	IGF1R	0.924
YWHAG	TP53	0.923
PPP2CA	CHEK1	0.923
PPP2CA	CTNNB1	0.923
IGF1R	RAF1	0.923
YWHAB	MAPK3	0.923
SOS1	IGF1	0.923
RPTOR	YWHAH	0.922
PPP2CA	XPO1	0.922
PPP2R1A	PPP3R1	0.922
CDK1	PPP2R1A	0.922
CSNK1E	YWHAQ	0.922
PPP2CA	YWHAE	0.922
YWHAZ	MAPK3	0.922
RAB14	VAMP2	0.922
YWHAQ	TP53	0.921
CDK1	YWHAG	0.921
HRAS	YWHAQ	0.921
MTOR	YWHAH	0.921
RAB10	YWHAH	0.921
CDK1	YWHAE	0.921
RASGRF1	CDK1	0.921
RASGRF1	NRAS	0.92
PPP2CA	HRAS	0.92
RAB14	RAB10	0.92
CTNNB1	YWHAE	0.92
YWHAZ	FOXO1	0.92
YWHAH	MAPK1	0.92
YWHAB	MAPK1	0.919
HRAS	YWHAE	0.919
YWHAQ	CTNNB1	0.919
YWHAQ	MAPK3	0.919
PPP2R2A	YWHAG	0.919
PPP2R1A	YWHAH	0.919
PPP2R1A	YWHAE	0.919
FOXO3	YWHAH	0.919
FOXO3	YWHAG	0.919
PPP2CA	RAF1	0.918
CSNK1E	CDK1	0.918
XPO1	YWHAZ	0.918
PPP2R1A	CSNK1D	0.918
PPP2CA	KRAS	0.918
YWHAB	TP53	0.918
RAN	YWHAG	0.918
YWHAG	PPP3R1	0.918
YWHAZ	YWHAB	0.918
YWHAZ	RAB10	0.917
XPO1	YWHAE	0.917
YWHAB	CTNNB1	0.917
CHEK1	PPP2R1A	0.917
PPP2R1A	MAP2K1	0.917
PPP2R1A	YWHAG	0.917
YWHAB	MAP2K1	0.917
CSNK1E	TP53	0.917
HRAS	YWHAG	0.917
YWHAH	TSC2	0.917
PPP2R2A	PPP3R1	0.917
YWHAE	RAF1	0.917
SOS1	YWHAH	0.917
YWHAQ	MTOR	0.916
CSNK1D	YWHAE	0.916
YWHAZ	NRAS	0.916
PPP2R2A	RAF1	0.916
PPP2R2B	YWHAQ	0.916
YWHAB	YWHAG	0.916
PPP2CA	PPP3R1	0.916
XPO1	YWHAB	0.916
SOS1	MTOR	0.916
YWHAZ	KRAS	0.916
CSNK1E	PPP2R1A	0.915
CSNK1E	YWHAH	0.915
YWHAZ	PPP2R1A	0.915
CHEK2	YWHAH	0.915
CTNNB1	YWHAH	0.915
XPO1	YWHAH	0.915
YWHAZ	YWHAG	0.915
YWHAZ	MAP2K1	0.915
YWHAQ	YWHAB	0.914
PPP2CA	NRAS	0.914
CHEK1	YWHAZ	0.914
YWHAE	MAPK3	0.914
PPP2CA	KSR1	0.914
YWHAQ	KRAS	0.914
YWHAZ	YWHAE	0.914
YWHAG	RAB10	0.914
CTNNB1	YWHAG	0.913
MLST8	YWHAQ	0.913
YWHAG	MAP2K1	0.913
YWHAG	YWHAH	0.913
YWHAB	NRAS	0.913
YWHAG	MAPK3	0.913
YWHAB	KRAS	0.913
TP53	YWHAH	0.912
MLST8	YWHAB	0.912
YWHAZ	PPP2R2A	0.912
MLST8	YWHAH	0.912
CSNK1D	TP53	0.912
MLST8	YWHAZ	0.912
MLST8	YWHAE	0.912
PPP2R2B	RAF1	0.912
MLST8	YWHAG	0.912
HRAS	YWHAH	0.911
KSR1	YWHAG	0.911
YWHAQ	CSNK1G3	0.911
VAMP2	YWHAG	0.911
FOXO3	FOXO1	0.911
YWHAQ	CSNK1D	0.911
YWHAZ	YWHAQ	0.911
YWHAQ	YWHAH	0.911
PPP2R2A	YWHAH	0.911
NRAS	YWHAE	0.91
YWHAB	YWHAH	0.91
MTOR	YWHAG	0.91
RAB14	NRAS	0.91
YWHAE	YWHAH	0.91
YWHAZ	VAMP2	0.91
YWHAG	CCNB1	0.91
XPO1	YWHAG	0.91
YWHAZ	CDC25C	0.91
RAB14	YWHAH	0.91
YWHAG	KRAS	0.909
KSR1	PPP2R2B	0.909
YWHAQ	PPP3R1	0.909
KRAS	YWHAH	0.909
KSR1	PPP2R2A	0.909
YWHAB	PPP2R2A	0.909
MTOR	YWHAE	0.909
RPTOR	YWHAG	0.909
NRAS	YWHAG	0.909
YWHAZ	LNPEP	0.909
YWHAG	LNPEP	0.909
RAB14	YWHAE	0.909
CHEK1	YWHAH	0.909
YWHAQ	MAP2K1	0.908
YWHAZ	PPP3R1	0.908
NRAS	YWHAH	0.908
VAMP2	YWHAE	0.908
YWHAQ	NRAS	0.908
YWHAB	LNPEP	0.908
FOXO1	MAPK3	0.908
PPP2R2B	YWHAG	0.908
YWHAQ	RPTOR	0.908
RAB14	YWHAB	0.908
NRAS	IGF1R	0.908
CDK1	YWHAH	0.908
PPP2R2B	YWHAB	0.908
PPP3CC	YWHAH	0.908
FOXO1	YWHAB	0.908
YWHAB	PPP3R1	0.908
YWHAE	KRAS	0.908
CDC25C	YWHAH	0.907
IGF1	YWHAH	0.907
YWHAQ	LNPEP	0.907
YWHAH	PPP3R1	0.907
YWHAE	LNPEP	0.907
PPP2R1A	RAF1	0.907
YWHAB	RAB10	0.907
YWHAQ	RAB14	0.907
YWHAZ	RPTOR	0.907
YWHAQ	CSNK1G1	0.907
MAPK3	YWHAH	0.907
MAP2K1	YWHAH	0.906
PPP2R2A	YWHAE	0.906
YWHAQ	VAMP2	0.906
PPP2R2B	YWHAE	0.906
PPP2R2B	MAP2K1	0.906
PPP2R2B	YWHAH	0.906
CHEK1	PPP2R2B	0.906
YWHAE	PPP3R1	0.906
IGF1R	YWHAH	0.906
FOXO1	YWHAH	0.906
YWHAH	LNPEP	0.906
YWHAZ	PPP2R2B	0.906
CSNK1D	YWHAH	0.906
CCNB1	YWHAH	0.906
YWHAE	TSC2	0.906
YWHAB	VAMP2	0.905
CSNK1E	YWHAB	0.905
CSNK1E	YWHAZ	0.905
FOXO1	YWHAE	0.905
YWHAQ	CDC25C	0.905
CSNK1E	YWHAE	0.905
YWHAZ	CSNK1D	0.905
YWHAB	CSNK1D	0.905
RAB10	YWHAE	0.905
YWHAE	CCNB1	0.905
VAMP2	YWHAH	0.905
KSR1	YWHAH	0.905
GRB2	YWHAH	0.905
YWHAQ	RAB10	0.905
PPP3CC	YWHAG	0.905
CSNK1G1	YWHAH	0.904
YWHAZ	CSNK1G3	0.904
CSNK1E	CSNK1D	0.904
YWHAB	CSNK1G1	0.904
CSNK1D	YWHAG	0.904
PPP3CC	YWHAB	0.904
CSNK1E	YWHAG	0.904
CHEK1	CHEK2	0.904
YWHAG	RAF1	0.904
YWHAG	CSNK1G2	0.904
CSNK1G3	YWHAE	0.904
RPTOR	YWHAE	0.904
RASGRF1	YWHAH	0.904
FOXO1	YWHAG	0.904
YWHAQ	CSNK1G2	0.904
NRAS	KRAS	0.904
YWHAZ	CSNK1G1	0.904
CSNK1G3	YWHAG	0.904
KSR1	PPP2R1A	0.904
YWHAB	CSNK1G2	0.904
AKT1S1	YWHAE	0.904
YWHAZ	CSNK1G2	0.904
YWHAB	CSNK1G3	0.904
CSNK1G2	YWHAH	0.904
CSNK1G1	YWHAE	0.904
YWHAG	CSNK1G1	0.904
CSNK1G3	YWHAH	0.904
YWHAE	CSNK1G2	0.904
RASGRF1	CCNB1	0.904
RASGRF1	CHEK2	0.903
RASGRF1	CHEK1	0.903
YWHAB	RPTOR	0.903
YWHAQ	FOXO1	0.903
PPP3CC	YWHAE	0.903
YWHAQ	RAF1	0.903
TP53	CSNK1G2	0.903
KSR1	YWHAE	0.903
PPP3CC	YWHAZ	0.903
PPP3CC	YWHAQ	0.903
KSR1	YWHAZ	0.902
RAN	FOXO1	0.902
KSR1	YWHAQ	0.902
NRAS	PPP2R1A	0.902
HRAS	NRAS	0.902
CSNK1G1	TP53	0.902
KSR1	YWHAB	0.902
HRAS	KRAS	0.902
YWHAQ	TSC2	0.902
MAPK3	MAPK1	0.902
CSNK1G3	TP53	0.901
YWHAG	TSC2	0.901
RAN	FOXO3	0.901
YWHAZ	AKT1S1	0.901
AKT1S1	YWHAB	0.9
AKT1S1	YWHAQ	0.9
FOXO1	CSNK1D	0.9
FOXO1	CSNK1G2	0.9
CSNK1E	FOXO1	0.9
FOXO1	CSNK1G3	0.9
FOXO1	CSNK1G1	0.9
AKT1S1	YWHAG	0.9

Gene Ontology Semantic Similarity

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#	2475 (MTOR)	983 (CDK1)	207 (AKT1)	995 (CDC25C)	11200 (CHEK2)	3479 (IGF1)	1111 (CHEK1)	64223 (MLST8)	5515 (PPP2CA)	6654 (SOS1)	57521 (RPTOR)	84335 (AKT1S1)	3265 (HRAS)	5901 (RAN)	2885 (GRB2)	5533 (PPP3CC)	5604 (MAP2K1)	5595 (MAPK3)	4893 (NRAS)	5520 (PPP2R2A)	8844 (KSR1)	3845 (KRAS)	7157 (TP53)	2308 (FOXO1)	2309 (FOXO3)	5521 (PPP2R2B)	7529 (YWHAB)	7249 (TSC2)	7534 (YWHAZ)	7532 (YWHAG)	51552 (RAB14)	7514 (XPO1)	5518 (PPP2R1A)	1499 (CTNNB1)	5894 (RAF1)	5923 (RASGRF1)	10890 (RAB10)	6844 (VAMP2)	3480 (IGF1R)	10971 (YWHAQ)	7531 (YWHAE)	7533 (YWHAH)	1453 (CSNK1D)	891 (CCNB1)	53944 (CSNK1G1)	1456 (CSNK1G3)	1455 (CSNK1G2)	5594 (MAPK1)	5534 (PPP3R1)	4012 (LNPEP)
2475 (MTOR)	1.00	0.78	0.71	0.47	0.76	0.52	0.78	0.46	0.46	0.41	0.72	1.00	0.45	0.45	0.65	0.49	0.73	0.77	0.50	0.44	0.51	0.50	0.57	0.56	0.53	0.46	0.62	0.51	0.63	0.56	0.43	0.46	0.47	0.59	0.81	0.17	0.43	0.57	0.66	0.57	0.60	0.58	0.74	0.66	0.71	0.45	0.71	0.78	0.50	0.43
983 (CDK1)	0.78	1.00	0.76	0.40	0.83	0.46	0.90	0.37	0.38	0.34	0.41	1.00	0.37	0.37	0.63	0.41	0.85	0.86	0.42	0.35	0.44	0.42	0.46	0.45	0.39	0.37	0.54	0.45	0.52	0.44	0.36	0.39	0.41	0.56	0.91	0.17	0.37	0.53	0.71	0.47	0.51	0.52	0.92	0.80	0.90	0.78	0.90	0.87	0.45	0.36
207 (AKT1)	0.71	0.76	1.00	0.47	0.78	0.50	0.76	0.47	0.45	0.47	0.50	1.00	0.54	0.49	0.64	0.47	0.75	0.77	0.48	0.48	0.49	0.48	0.55	0.50	0.44	0.45	0.60	0.57	0.58	0.53	0.53	0.46	0.50	0.59	0.81	0.22	0.53	0.61	0.66	0.54	0.59	0.60	0.72	0.71	0.69	0.43	0.69	0.77	0.50	0.43
995 (CDC25C)	0.47	0.40	0.47	1.00	0.62	0.60	0.48	0.53	0.86	0.44	0.54	1.00	0.51	0.44	0.58	0.77	0.48	0.51	0.59	0.75	0.62	0.59	0.52	0.54	0.50	0.83	0.69	0.57	0.70	0.61	0.49	0.52	0.74	0.65	0.54	0.19	0.49	0.65	0.50	0.65	0.59	0.66	0.51	0.50	0.53	0.13	0.53	0.48	0.73	0.49
11200 (CHEK2)	0.76	0.83	0.78	0.62	1.00	0.61	0.85	0.56	0.55	0.48	0.55	1.00	0.52	0.46	0.71	0.59	0.77	0.87	0.61	0.53	0.63	0.61	0.56	0.61	0.52	0.57	0.72	0.65	0.78	0.66	0.50	0.55	0.56	0.66	0.92	0.19	0.50	0.66	0.69	0.71	0.65	0.69	0.82	0.77	0.81	0.46	0.81	0.88	0.58	0.49
3479 (IGF1)	0.52	0.46	0.50	0.60	0.61	1.00	0.53	0.65	0.60	0.52	0.54	1.00	0.57	0.48	0.59	0.67	0.54	0.58	0.72	0.59	0.71	0.72	0.52	0.61	0.51	0.65	0.73	0.65	0.71	0.70	0.55	0.62	0.61	0.67	0.59	0.20	0.54	0.72	0.61	0.76	0.63	0.75	0.60	0.51	0.65	0.11	0.65	0.54	0.63	0.51
1111 (CHEK1)	0.78	0.90	0.76	0.48	0.85	0.53	1.00	0.44	0.45	0.38	0.45	1.00	0.43	0.40	0.65	0.48	0.83	0.89	0.50	0.42	0.51	0.50	0.48	0.50	0.42	0.44	0.63	0.51	0.58	0.49	0.41	0.45	0.47	0.60	0.93	0.19	0.41	0.59	0.70	0.56	0.55	0.61	0.90	0.75	0.89	0.72	0.89	0.89	0.54	0.41
64223 (MLST8)	0.46	0.37	0.47	0.53	0.56	0.65	0.44	1.00	0.51	0.49	0.63	1.00	0.48	0.42	0.56	0.61	0.63	0.51	0.68	0.55	0.67	0.68	0.50	0.56	0.45	0.56	0.72	0.67	0.68	0.65	0.45	0.53	0.59	0.66	0.53	0.25	0.46	0.71	0.50	0.75	0.60	0.69	0.51	0.60	0.56	0.12	0.56	0.46	0.59	0.42
5515 (PPP2CA)	0.46	0.38	0.45	0.86	0.55	0.60	0.45	0.51	1.00	0.42	0.48	1.00	0.50	0.47	0.54	0.83	0.47	0.51	0.59	0.82	0.60	0.59	0.51	0.54	0.45	0.93	0.67	0.57	0.64	0.55	0.47	0.51	0.86	0.64	0.52	0.20	0.47	0.66	0.49	0.66	0.61	0.69	0.50	0.43	0.52	0.14	0.52	0.47	0.75	0.48
6654 (SOS1)	0.41	0.34	0.47	0.44	0.48	0.52	0.38	0.49	0.42	1.00	0.49	1.00	0.41	0.39	0.65	0.47	0.46	0.43	0.49	0.49	0.51	0.49	0.48	0.49	0.41	0.42	0.60	0.67	0.58	0.51	0.39	0.44	0.53	0.60	0.44	0.78	0.39	0.60	0.46	0.55	0.68	0.65	0.42	0.45	0.42	0.12	0.42	0.41	0.50	0.36
57521 (RPTOR)	0.72	0.41	0.50	0.54	0.55	0.54	0.45	0.63	0.48	0.49	1.00	1.00	0.47	0.49	0.60	0.51	0.56	0.48	0.59	0.51	0.54	0.59	0.61	0.60	0.59	0.49	0.60	0.57	0.66	0.70	0.46	0.49	0.53	0.63	0.50	0.20	0.46	0.59	0.48	0.56	0.59	0.60	0.48	0.59	0.49	0.09	0.49	0.46	0.52	0.44
84335 (AKT1S1)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.26	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.14	1.00	1.00	1.00	1.00
3265 (HRAS)	0.45	0.37	0.54	0.51	0.52	0.57	0.43	0.48	0.50	0.41	0.47	1.00	1.00	0.70	0.53	0.53	0.48	0.48	0.55	0.46	0.61	0.55	0.54	0.53	0.45	0.50	0.65	0.55	0.63	0.54	0.94	0.48	0.51	0.64	0.49	0.18	0.90	0.65	0.48	0.61	0.58	0.62	0.47	0.42	0.48	0.11	0.48	0.45	0.55	0.44
5901 (RAN)	0.45	0.37	0.49	0.44	0.46	0.48	0.40	0.42	0.47	0.39	0.49	1.00	0.70	1.00	0.55	0.45	0.42	0.43	0.49	0.42	0.47	0.49	0.62	0.56	0.51	0.43	0.57	0.47	0.64	0.56	0.69	0.54	0.48	0.71	0.44	0.17	0.69	0.54	0.45	0.49	0.62	0.58	0.46	0.40	0.42	0.10	0.42	0.42	0.51	0.44
2885 (GRB2)	0.65	0.63	0.64	0.58	0.71	0.59	0.65	0.56	0.54	0.65	0.60	1.00	0.53	0.55	1.00	0.57	0.63	0.66	0.58	0.54	0.59	0.58	0.58	0.58	0.58	0.55	0.66	0.59	0.72	0.68	0.52	0.55	0.56	0.63	0.68	0.31	0.52	0.62	0.63	0.63	0.70	0.66	0.64	0.64	0.63	0.23	0.63	0.65	0.57	0.50
5533 (PPP3CC)	0.49	0.41	0.47	0.77	0.59	0.67	0.48	0.61	0.83	0.47	0.51	1.00	0.53	0.45	0.57	1.00	0.50	0.55	0.70	0.76	0.70	0.70	0.51	0.58	0.48	0.88	0.72	0.63	0.69	0.61	0.51	0.58	0.75	0.67	0.56	0.21	0.50	0.75	0.52	0.76	0.61	0.69	0.56	0.46	0.61	0.13	0.61	0.50	0.80	0.48
5604 (MAP2K1)	0.73	0.85	0.75	0.48	0.77	0.54	0.83	0.63	0.47	0.46	0.56	1.00	0.48	0.42	0.63	0.50	1.00	0.79	0.52	0.48	0.56	0.52	0.50	0.51	0.44	0.48	0.60	0.56	0.58	0.54	0.44	0.48	0.51	0.61	0.84	0.20	0.44	0.59	0.69	0.59	0.57	0.59	0.83	0.83	0.81	0.56	0.81	0.80	0.52	0.43
5595 (MAPK3)	0.77	0.86	0.77	0.51	0.87	0.58	0.89	0.51	0.51	0.43	0.48	1.00	0.48	0.43	0.66	0.55	0.79	1.00	0.57	0.48	0.58	0.57	0.52	0.55	0.45	0.52	0.68	0.62	0.64	0.57	0.46	0.51	0.52	0.64	0.94	0.20	0.46	0.63	0.70	0.66	0.60	0.66	0.86	0.71	0.87	0.59	0.87	0.99	0.60	0.45
4893 (NRAS)	0.50	0.42	0.48	0.59	0.61	0.72	0.50	0.68	0.59	0.49	0.59	1.00	0.55	0.49	0.58	0.70	0.52	0.57	1.00	0.58	0.77	1.00	0.54	0.66	0.50	0.68	0.76	0.67	0.73	0.64	0.52	0.62	0.61	0.71	0.58	0.25	0.52	0.75	0.53	0.84	0.62	0.72	0.59	0.47	0.68	0.14	0.68	0.52	0.64	0.47
5520 (PPP2R2A)	0.44	0.35	0.48	0.75	0.53	0.59	0.42	0.55	0.82	0.49	0.51	1.00	0.46	0.42	0.54	0.76	0.48	0.48	0.58	1.00	0.59	0.58	0.49	0.53	0.43	0.84	0.67	0.61	0.64	0.57	0.44	0.49	0.93	0.64	0.49	0.31	0.44	0.66	0.48	0.66	0.60	0.66	0.47	0.46	0.49	0.13	0.49	0.44	0.70	0.43
8844 (KSR1)	0.51	0.44	0.49	0.62	0.63	0.71	0.51	0.67	0.60	0.51	0.54	1.00	0.61	0.47	0.59	0.70	0.56	0.58	0.77	0.59	1.00	0.77	0.52	0.61	0.50	0.68	0.76	0.67	0.73	0.65	0.54	0.63	0.62	0.71	0.60	0.22	0.53	0.74	0.54	0.81	0.63	0.72	0.60	0.50	0.68	0.12	0.68	0.53	0.64	0.50
3845 (KRAS)	0.50	0.42	0.48	0.59	0.61	0.72	0.50	0.68	0.59	0.49	0.59	1.00	0.55	0.49	0.58	0.70	0.52	0.57	1.00	0.58	0.77	1.00	0.54	0.66	0.50	0.68	0.76	0.67	0.73	0.64	0.52	0.62	0.61	0.71	0.58	0.25	0.52	0.75	0.53	0.84	0.62	0.72	0.59	0.47	0.68	0.14	0.68	0.52	0.64	0.47
7157 (TP53)	0.57	0.46	0.55	0.52	0.56	0.52	0.48	0.50	0.51	0.48	0.61	1.00	0.54	0.62	0.58	0.51	0.50	0.52	0.54	0.49	0.52	0.54	1.00	0.76	0.75	0.50	0.60	0.54	0.65	0.59	0.53	0.50	0.52	0.66	0.54	0.17	0.53	0.55	0.50	0.55	0.64	0.59	0.50	0.51	0.50	0.09	0.50	0.51	0.55	0.52
2308 (FOXO1)	0.56	0.45	0.50	0.54	0.61	0.61	0.50	0.56	0.54	0.49	0.60	1.00	0.53	0.56	0.58	0.58	0.51	0.55	0.66	0.53	0.61	0.66	0.76	1.00	0.82	0.56	0.67	0.61	0.74	0.61	0.52	0.56	0.56	0.72	0.56	0.21	0.51	0.65	0.52	0.64	0.65	0.65	0.54	0.51	0.56	0.11	0.56	0.52	0.59	0.48
2309 (FOXO3)	0.53	0.39	0.44	0.50	0.52	0.51	0.42	0.45	0.45	0.41	0.59	1.00	0.45	0.51	0.58	0.48	0.44	0.45	0.50	0.43	0.50	0.50	0.75	0.82	1.00	0.45	0.57	0.50	0.68	0.60	0.44	0.46	0.47	0.63	0.47	0.19	0.44	0.56	0.46	0.52	0.59	0.56	0.45	0.46	0.45	0.10	0.45	0.44	0.49	0.41
5521 (PPP2R2B)	0.46	0.37	0.45	0.83	0.57	0.65	0.44	0.56	0.93	0.42	0.49	1.00	0.50	0.43	0.55	0.88	0.48	0.52	0.68	0.84	0.68	0.68	0.50	0.56	0.45	1.00	0.72	0.61	0.68	0.58	0.47	0.54	0.80	0.66	0.53	0.22	0.47	0.71	0.50	0.75	0.60	0.68	0.52	0.43	0.56	0.14	0.56	0.47	0.76	0.46
7529 (YWHAB)	0.62	0.54	0.60	0.69	0.72	0.73	0.63	0.72	0.67	0.60	0.60	1.00	0.65	0.57	0.66	0.72	0.60	0.68	0.76	0.67	0.76	0.76	0.60	0.67	0.57	0.72	1.00	0.73	0.81	0.72	0.64	0.69	0.67	0.75	0.71	0.21	0.64	0.75	0.61	0.82	0.81	0.80	0.72	0.59	0.72	0.11	0.72	0.64	0.72	0.59
7249 (TSC2)	0.51	0.45	0.57	0.57	0.65	0.65	0.51	0.67	0.57	0.67	0.57	1.00	0.55	0.47	0.59	0.63	0.56	0.62	0.67	0.61	0.67	0.67	0.54	0.61	0.50	0.61	0.73	1.00	0.68	0.64	0.53	0.59	0.63	0.68	0.61	0.23	0.52	0.69	0.54	0.72	0.64	0.71	0.57	0.53	0.61	0.11	0.61	0.58	0.66	0.50
7534 (YWHAZ)	0.63	0.52	0.58	0.70	0.78	0.71	0.58	0.68	0.64	0.58	0.66	1.00	0.63	0.64	0.72	0.69	0.58	0.64	0.73	0.64	0.73	0.73	0.65	0.74	0.68	0.68	0.81	0.68	1.00	0.82	0.61	0.66	0.65	0.77	0.67	0.20	0.62	0.73	0.59	0.79	0.79	0.77	0.69	0.62	0.68	0.11	0.68	0.61	0.66	0.57
7532 (YWHAG)	0.56	0.44	0.53	0.61	0.66	0.70	0.49	0.65	0.55	0.51	0.70	1.00	0.54	0.56	0.68	0.61	0.54	0.57	0.64	0.57	0.65	0.64	0.59	0.61	0.60	0.58	0.72	0.64	0.82	1.00	0.52	0.56	0.59	0.66	0.59	0.21	0.52	0.68	0.54	0.73	0.68	0.74	0.55	0.58	0.58	0.10	0.58	0.53	0.59	0.48
51552 (RAB14)	0.43	0.36	0.53	0.49	0.50	0.55	0.41	0.45	0.47	0.39	0.46	1.00	0.94	0.69	0.52	0.51	0.44	0.46	0.52	0.44	0.54	0.52	0.53	0.52	0.44	0.47	0.64	0.53	0.61	0.52	1.00	0.45	0.49	0.61	0.47	0.17	0.95	0.63	0.47	0.59	0.57	0.60	0.45	0.41	0.45	0.10	0.45	0.43	0.53	0.42
7514 (XPO1)	0.46	0.39	0.46	0.52	0.55	0.62	0.45	0.53	0.51	0.44	0.49	1.00	0.48	0.54	0.55	0.58	0.48	0.51	0.62	0.49	0.63	0.62	0.50	0.56	0.46	0.54	0.69	0.59	0.66	0.56	0.45	1.00	0.54	0.65	0.52	0.28	0.45	0.68	0.50	0.69	0.60	0.66	0.51	0.44	0.54	0.15	0.54	0.47	0.57	0.43
5518 (PPP2R1A)	0.47	0.41	0.50	0.74	0.56	0.61	0.47	0.59	0.86	0.53	0.53	1.00	0.51	0.48	0.56	0.75	0.51	0.52	0.61	0.93	0.62	0.61	0.52	0.56	0.47	0.80	0.67	0.63	0.65	0.59	0.49	0.54	1.00	0.64	0.53	0.27	0.49	0.67	0.51	0.67	0.64	0.71	0.52	0.50	0.55	0.12	0.55	0.49	0.70	0.48
1499 (CTNNB1)	0.59	0.56	0.59	0.65	0.66	0.67	0.60	0.66	0.64	0.60	0.63	1.00	0.64	0.71	0.63	0.67	0.61	0.64	0.71	0.64	0.71	0.71	0.66	0.72	0.63	0.66	0.75	0.68	0.77	0.66	0.61	0.65	0.64	1.00	0.66	0.19	0.62	0.69	0.59	0.70	0.69	0.76	0.66	0.60	0.66	0.10	0.66	0.62	0.67	0.59
5894 (RAF1)	0.81	0.91	0.81	0.54	0.92	0.59	0.93	0.53	0.52	0.44	0.50	1.00	0.49	0.44	0.68	0.56	0.84	0.94	0.58	0.49	0.60	0.58	0.54	0.56	0.47	0.53	0.71	0.61	0.67	0.59	0.47	0.52	0.53	0.66	1.00	0.20	0.47	0.64	0.74	0.68	0.62	0.68	0.91	0.77	0.90	0.64	0.90	0.94	0.58	0.47
5923 (RASGRF1)	0.17	0.17	0.22	0.19	0.19	0.20	0.19	0.25	0.20	0.78	0.20	0.26	0.18	0.17	0.31	0.21	0.20	0.20	0.25	0.31	0.22	0.25	0.17	0.21	0.19	0.22	0.21	0.23	0.20	0.21	0.17	0.28	0.27	0.19	0.20	1.00	0.16	0.21	0.17	0.23	0.32	0.27	0.20	0.22	0.22	0.13	0.22	0.19	0.20	0.19
10890 (RAB10)	0.43	0.37	0.53	0.49	0.50	0.54	0.41	0.46	0.47	0.39	0.46	1.00	0.90	0.69	0.52	0.50	0.44	0.46	0.52	0.44	0.53	0.52	0.53	0.51	0.44	0.47	0.64	0.52	0.62	0.52	0.95	0.45	0.49	0.62	0.47	0.16	1.00	0.62	0.47	0.57	0.57	0.59	0.48	0.41	0.46	0.10	0.46	0.44	0.53	0.43
6844 (VAMP2)	0.57	0.53	0.61	0.65	0.66	0.72	0.59	0.71	0.66	0.60	0.59	1.00	0.65	0.54	0.62	0.75	0.59	0.63	0.75	0.66	0.74	0.75	0.55	0.65	0.56	0.71	0.75	0.69	0.73	0.68	0.63	0.68	0.67	0.69	0.64	0.21	0.62	1.00	0.59	0.78	0.65	0.72	0.66	0.56	0.71	0.11	0.71	0.60	0.70	0.58
3480 (IGF1R)	0.66	0.71	0.66	0.50	0.69	0.61	0.70	0.50	0.49	0.46	0.48	1.00	0.48	0.45	0.63	0.52	0.69	0.70	0.53	0.48	0.54	0.53	0.50	0.52	0.46	0.50	0.61	0.54	0.59	0.54	0.47	0.50	0.51	0.59	0.74	0.17	0.47	0.59	1.00	0.59	0.57	0.60	0.70	0.64	0.67	0.35	0.67	0.70	0.53	0.47
10971 (YWHAQ)	0.57	0.47	0.54	0.65	0.71	0.76	0.56	0.75	0.66	0.55	0.56	1.00	0.61	0.49	0.63	0.76	0.59	0.66	0.84	0.66	0.81	0.84	0.55	0.64	0.52	0.75	0.82	0.72	0.79	0.73	0.59	0.69	0.67	0.70	0.68	0.23	0.57	0.78	0.59	1.00	0.67	0.78	0.66	0.52	0.75	0.13	0.75	0.61	0.68	0.54
7531 (YWHAE)	0.60	0.51	0.59	0.59	0.65	0.63	0.55	0.60	0.61	0.68	0.59	1.00	0.58	0.62	0.70	0.61	0.57	0.60	0.62	0.60	0.63	0.62	0.64	0.65	0.59	0.60	0.81	0.64	0.79	0.68	0.57	0.60	0.64	0.69	0.62	0.32	0.57	0.65	0.57	0.67	1.00	0.78	0.61	0.57	0.60	0.10	0.60	0.58	0.61	0.54
7533 (YWHAH)	0.58	0.52	0.60	0.66	0.69	0.75	0.61	0.69	0.69	0.65	0.60	1.00	0.62	0.58	0.66	0.69	0.59	0.66	0.72	0.66	0.72	0.72	0.59	0.65	0.56	0.68	0.80	0.71	0.77	0.74	0.60	0.66	0.71	0.76	0.68	0.27	0.59	0.72	0.60	0.78	0.78	1.00	0.64	0.59	0.68	0.11	0.68	0.62	0.69	0.57
1453 (CSNK1D)	0.74	0.92	0.72	0.51	0.82	0.60	0.90	0.51	0.50	0.42	0.48	1.00	0.47	0.46	0.64	0.56	0.83	0.86	0.59	0.47	0.60	0.59	0.50	0.54	0.45	0.52	0.72	0.57	0.69	0.55	0.45	0.51	0.52	0.66	0.91	0.20	0.48	0.66	0.70	0.66	0.61	0.64	1.00	0.73	0.93	0.71	0.93	0.86	0.56	0.43
891 (CCNB1)	0.66	0.80	0.71	0.50	0.77	0.51	0.75	0.60	0.43	0.45	0.59	1.00	0.42	0.40	0.64	0.46	0.83	0.71	0.47	0.46	0.50	0.47	0.51	0.51	0.46	0.43	0.59	0.53	0.62	0.58	0.41	0.44	0.50	0.60	0.77	0.22	0.41	0.56	0.64	0.52	0.57	0.59	0.73	1.00	0.69	0.47	0.69	0.71	0.49	0.40
53944 (CSNK1G1)	0.71	0.90	0.69	0.53	0.81	0.65	0.89	0.56	0.52	0.42	0.49	1.00	0.48	0.42	0.63	0.61	0.81	0.87	0.68	0.49	0.68	0.68	0.50	0.56	0.45	0.56	0.72	0.61	0.68	0.58	0.45	0.54	0.55	0.66	0.90	0.22	0.46	0.71	0.67	0.75	0.60	0.68	0.93	0.69	1.00	0.76	1.00	0.87	0.59	0.42
1456 (CSNK1G3)	0.45	0.78	0.43	0.13	0.46	0.11	0.72	0.12	0.14	0.12	0.09	0.14	0.11	0.10	0.23	0.13	0.56	0.59	0.14	0.13	0.12	0.14	0.09	0.11	0.10	0.14	0.11	0.11	0.11	0.10	0.10	0.15	0.12	0.10	0.64	0.13	0.10	0.11	0.35	0.13	0.10	0.11	0.71	0.47	0.76	1.00	0.76	0.63	0.11	0.14
1455 (CSNK1G2)	0.71	0.90	0.69	0.53	0.81	0.65	0.89	0.56	0.52	0.42	0.49	1.00	0.48	0.42	0.63	0.61	0.81	0.87	0.68	0.49	0.68	0.68	0.50	0.56	0.45	0.56	0.72	0.61	0.68	0.58	0.45	0.54	0.55	0.66	0.90	0.22	0.46	0.71	0.67	0.75	0.60	0.68	0.93	0.69	1.00	0.76	1.00	0.87	0.59	0.42
5594 (MAPK1)	0.78	0.87	0.77	0.48	0.88	0.54	0.89	0.46	0.47	0.41	0.46	1.00	0.45	0.42	0.65	0.50	0.80	0.99	0.52	0.44	0.53	0.52	0.51	0.52	0.44	0.47	0.64	0.58	0.61	0.53	0.43	0.47	0.49	0.62	0.94	0.19	0.44	0.60	0.70	0.61	0.58	0.62	0.86	0.71	0.87	0.63	0.87	1.00	0.56	0.43
5534 (PPP3R1)	0.50	0.45	0.50	0.73	0.58	0.63	0.54	0.59	0.75	0.50	0.52	1.00	0.55	0.51	0.57	0.80	0.52	0.60	0.64	0.70	0.64	0.64	0.55	0.59	0.49	0.76	0.72	0.66	0.66	0.59	0.53	0.57	0.70	0.67	0.58	0.20	0.53	0.70	0.53	0.68	0.61	0.69	0.56	0.49	0.59	0.11	0.59	0.56	1.00	0.61
4012 (LNPEP)	0.43	0.36	0.43	0.49	0.49	0.51	0.41	0.42	0.48	0.36	0.44	1.00	0.44	0.44	0.50	0.48	0.43	0.45	0.47	0.43	0.50	0.47	0.52	0.48	0.41	0.46	0.59	0.50	0.57	0.48	0.42	0.43	0.48	0.59	0.47	0.19	0.43	0.58	0.47	0.54	0.54	0.57	0.43	0.40	0.42	0.14	0.42	0.43	0.61	1.00

Association with High Altitude

Protein Official symbol	Source Organism	Tissue of Expression	Level of hypoxia	Altitude	Duration of experiment	Level of expression	Fold change	Experiment details	geographical location	ethnicity of the patients	Control group	Control (Fold change)	Reference (PMID)
YWHAH	Human	Blood	-	3600 m	Native	upregulated	-	TMT-based proteomic analysis/LC-MS	Central Asia	Tibetans	-	High altitude native vs. low Lander	30908922

Association with TF

TF	TF Entrez	Gene	Gene Entrez	Type	PMID	Database

Association with miRNA

miRTarBase ID	miRNA	Species (miRNA)	Protein Official Symbol	Human Entrez ID	Species (Target Gene)	Experiments	Support Type	References (PMID)
MIRT021116	hsa-miR-186-5p	Homo sapiens	YWHAH	7533	Homo sapiens	Sequencing	Functional MTI (Weak)	20371350
MIRT021116	hsa-miR-186-5p	Homo sapiens	YWHAH	7533	Homo sapiens	CLASH	Functional MTI (Weak)	23622248
MIRT027235	hsa-miR-103a-3p	Homo sapiens	YWHAH	7533	Homo sapiens	Sequencing//PAR-CLIP	Functional MTI (Weak)	20371350
MIRT028247	hsa-miR-33a-5p	Homo sapiens	YWHAH	7533	Homo sapiens	Sequencing//PAR-CLIP	Functional MTI (Weak)	20371350
MIRT028247	hsa-miR-33a-5p	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT028327	hsa-miR-32-5p	Homo sapiens	YWHAH	7533	Homo sapiens	Sequencing	Functional MTI (Weak)	20371350
MIRT032075	hsa-miR-16-5p	Homo sapiens	YWHAH	7533	Homo sapiens	Sequencing//PAR-CLIP	Functional MTI (Weak)	20371350
MIRT032075	hsa-miR-16-5p	Homo sapiens	YWHAH	7533	Homo sapiens	Proteomics	Functional MTI (Weak)	18668040
MIRT043064	hsa-miR-324-5p	Homo sapiens	YWHAH	7533	Homo sapiens	CLASH	Functional MTI (Weak)	23622248
MIRT087559	hsa-miR-424-5p	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT087552	hsa-miR-4748	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT087561	hsa-miR-660-5p	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT087540	hsa-miR-5696	Homo sapiens	YWHAH	7533	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	19536157
MIRT087549	hsa-miR-2113	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT087539	hsa-miR-664b-3p	Homo sapiens	YWHAH	7533	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	19536157
MIRT087528	hsa-miR-153-5p	Homo sapiens	YWHAH	7533	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	19536157
MIRT087548	hsa-miR-33b-5p	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT087553	hsa-miR-5087	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT087566	hsa-miR-4729	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT087549	hsa-miR-2113	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT087547	hsa-miR-598-3p	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT087551	hsa-miR-4464	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT087556	hsa-miR-15b-5p	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT087560	hsa-miR-497-5p	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT087531	hsa-miR-579-3p	Homo sapiens	YWHAH	7533	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	19536157
MIRT087533	hsa-miR-1250-3p	Homo sapiens	YWHAH	7533	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	19536157
MIRT087553	hsa-miR-5087	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT087555	hsa-miR-107	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT087568	hsa-miR-6838-5p	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT087567	hsa-miR-5591-3p	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT087551	hsa-miR-4464	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT087548	hsa-miR-33b-5p	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT087554	hsa-miR-15a-5p	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT087552	hsa-miR-4748	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT087558	hsa-miR-330-3p	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT087557	hsa-miR-195-5p	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT087564	hsa-miR-4310	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT087569	hsa-miR-7157-5p	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT254727	hsa-miR-186-3p	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT301127	hsa-miR-586	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT301127	hsa-miR-586	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT301126	hsa-miR-583	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT520014	hsa-miR-4669	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT520015	hsa-miR-3657	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT520014	hsa-miR-4669	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT520016	hsa-miR-1289	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT520015	hsa-miR-3657	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT520013	hsa-miR-142-3p	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT520017	hsa-miR-4267	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT520018	hsa-miR-648	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT520017	hsa-miR-4267	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT520013	hsa-miR-142-3p	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT520018	hsa-miR-648	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT552703	hsa-miR-4311	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT552700	hsa-miR-1245b-3p	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT552699	hsa-miR-5100	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT552702	hsa-miR-1276	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT552698	hsa-miR-3942-3p	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT552701	hsa-miR-32-3p	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT561356	hsa-miR-6793-3p	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT561357	hsa-miR-4699-3p	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT561358	hsa-miR-198	Homo sapiens	YWHAH	7533	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT713121	hsa-miR-30e-3p	Homo sapiens	YWHAH	7533	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	19536157
MIRT713124	hsa-miR-205-5p	Homo sapiens	YWHAH	7533	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	19536157
MIRT713127	hsa-miR-34b-3p	Homo sapiens	YWHAH	7533	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	19536157
MIRT713123	hsa-miR-30a-3p	Homo sapiens	YWHAH	7533	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	19536157
MIRT713126	hsa-miR-6865-3p	Homo sapiens	YWHAH	7533	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	19536157
MIRT713125	hsa-miR-3620-3p	Homo sapiens	YWHAH	7533	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	19536157
MIRT713122	hsa-miR-30d-3p	Homo sapiens	YWHAH	7533	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	19536157

Gene Ontology

ID	GO ID	GO Term	GO Type
7533	GO:0045893	positive regulation of transcription	GOTERM_BP_DIRECT
7533	GO:0048167	regulation of synaptic plasticity	GOTERM_BP_DIRECT
7533	GO:0035259	nuclear hormone receptor binding	GOTERM_MF_DIRECT
7533	GO:0021762	substantia nigra development	GOTERM_BP_DIRECT
7533	GO:0050774	negative regulation of dendrite morphogenesis	GOTERM_BP_DIRECT
7533	GO:0019899	enzyme binding	GOTERM_MF_DIRECT
7533	GO:0044325	ion channel binding	GOTERM_MF_DIRECT
7533	GO:0046982	protein heterodimerization activity	GOTERM_MF_DIRECT
7533	GO:0002028	regulation of sodium ion transport	GOTERM_BP_DIRECT
7533	GO:0042921	glucocorticoid receptor signaling pathway	GOTERM_BP_DIRECT
7533	GO:0014704	intercalated disc	GOTERM_CC_DIRECT
7533	GO:0070062	extracellular exosome	GOTERM_CC_DIRECT
7533	GO:0006713	glucocorticoid catabolic process	GOTERM_BP_DIRECT
7533	GO:0045664	regulation of neuron differentiation	GOTERM_BP_DIRECT
7533	GO:0086010	membrane depolarization during action potential	GOTERM_BP_DIRECT
7533	GO:0004497	monooxygenase activity	GOTERM_MF_DIRECT
7533	GO:0005515	protein binding	GOTERM_MF_DIRECT
7533	GO:0030659	cytoplasmic vesicle membrane	GOTERM_CC_DIRECT
7533	GO:0061024	membrane organization	GOTERM_BP_DIRECT
7533	GO:1900740	positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	GOTERM_BP_DIRECT
7533	GO:0006886	intracellular protein transport	GOTERM_BP_DIRECT
7533	GO:0019904	protein domain specific binding	GOTERM_MF_DIRECT
7533	GO:2000649	regulation of sodium ion transmembrane transporter activity	GOTERM_BP_DIRECT
7533	GO:0005739	mitochondrion	GOTERM_CC_DIRECT
7533	GO:0003779	actin binding	GOTERM_MF_DIRECT
7533	GO:0005737	cytoplasm	GOTERM_CC_DIRECT
7533	GO:0005159	interleukin-6 receptor binding	GOTERM_MF_DIRECT
7533	GO:0017080	snRNA binding	GOTERM_MF_DIRECT
7533	GO:0005829	cytosol	GOTERM_CC_DIRECT
7533	GO:0005886	plasma membrane	GOTERM_CC_DIRECT

Pathways

Human Entrez ID	KEGG ID	KEGG Term
7533	hsa04110	Cell cycle
7533	hsa04114	Oocyte meiosis
7533	hsa04151	PI3K-Akt signaling pathway
7533	hsa04390	Hippo signaling pathway
7533	hsa05203	Viral carcinogenesis

Association with Disease

Protein Official Symbol	Human Entrez ID	Disease Name	Disease Id	Disease Semantic Type	Semantic score	DSI	DPI	Disease Type
YWHAH	7533	Cardiomyopathies	C0878544	Disease or Syndrome	0.3	0.743	0.207	group
YWHAH	7533	Alloxan Diabetes	C0002152	Experimental Model of Disease	0.3	0.743	0.207	disease
YWHAH	7533	Diabetes Mellitus, Experimental	C0011853	Experimental Model of Disease	0.3	0.743	0.207	disease
YWHAH	7533	Myocardial Diseases, Secondary	C0036529	Disease or Syndrome	0.3	0.743	0.207	group
YWHAH	7533	Streptozotocin Diabetes	C0038433	Experimental Model of Disease	0.3	0.743	0.207	disease
YWHAH	7533	Cardiomyopathies, Primary	C0033141	Disease or Syndrome	0.3	0.743	0.207	group
YWHAH	7533	Bipolar Disorder	C0005586	Mental or Behavioral Dysfunction	0.31	0.743	0.207	disease
YWHAH	7533	Schizophrenia	C0036341	Mental or Behavioral Dysfunction	0.04	0.743	0.207	disease

Association with Drug

Protein Official Symbol	Human Entrez ID	drug_claim_primary_name	drug_name	drug_chembl_id	interaction_types