ALTITUDEOMICSDB

14-3-3 protein

AltitudeomicsDB

Protein Official symbol	YWHAB
Aliases	YWHAB
Chromosomal Location	20
Length	246
Uniprot ID	P31946
EC number	None
Protein family Information(Pfam)	PF00244;
PDB id	2BQ0;2C23;4DNK;5N10;6A5Q;6BYK;6GN0;6GN8;6GNJ;6GNK;6GNN;6HEP;
InterPro ID	IPR000308;IPR023409;IPR036815;IPR023410;
dbSNP	None

Protein Protein Interaction

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AltitudeomicsDB

Protein 1	Protein 2	Combine Score
MAP2K1	BRAF	0.9990000000000001
AKT1	PPP2CA	0.9990000000000001
HRAS	RAF1	0.9990000000000001
PPP2R1A	PPP2CB	0.9990000000000001
TSC1	TSC2	0.9990000000000001
MTOR	RPS6KB1	0.9990000000000001
PPP2CA	PPP2R1A	0.9990000000000001
AKT1	FOXO3	0.9990000000000001
YWHAZ	YWHAB	0.9990000000000001
MTOR	RHEB	0.9990000000000001
AKT1	MTOR	0.9990000000000001
RHEB	TSC2	0.9990000000000001
AKT1S1	MTOR	0.998
AKT1	TSC2	0.998
RAP1A	RAF1	0.998
YWHAZ	RAF1	0.998
TSC1	RHEB	0.998
MTOR	TSC2	0.998
KSR2	MAP2K1	0.998
CBY1	YWHAZ	0.997
YWHAZ	YWHAH	0.997
YWHAB	YWHAH	0.997
YWHAG	YWHAH	0.997
HRAS	BRAF	0.997
AKT1	AKT1S1	0.996
NRAS	RAF1	0.996
HRAS	NRAS	0.995
KSR1	MAP2K1	0.995
AKT1	CDKN1B	0.995
NRAS	BRAF	0.995
KSR1	MAP2K2	0.9940000000000001
HRAS	ARAF	0.9940000000000001
RHEB	RPS6KB1	0.9940000000000001
BRAF	MAP2K2	0.9940000000000001
FOXO3	BCL2L11	0.9940000000000001
NRAS	ARAF	0.9940000000000001
HRAS	MAP2K1	0.9940000000000001
AKT1	TP53	0.9940000000000001
AKT1	BAD	0.993
AKT1	RPS6KB1	0.992
ARAF	MAP2K2	0.992
CDC25C	TP53	0.992
YWHAZ	CDC25C	0.992
YWHAG	YWHAE	0.992
AKT1	TBC1D4	0.992
HRAS	SRC	0.991
YWHAB	YWHAE	0.991
PPP2CA	PPP2CB	0.99
YWHAZ	YWHAG	0.9890000000000001
MAP2K1	RAF1	0.9890000000000001
KSR2	MAP2K2	0.9890000000000001
MAP2K1	ARAF	0.988
AKT1	TSC1	0.988
PEBP1	RAF1	0.988
MAP2K2	RAF1	0.988
ITGA6	ITGB4	0.988
YWHAE	RAF1	0.988
CBY1	SFN	0.988
YWHAB	RAF1	0.988
FOXO3	CDKN1B	0.987
SFN	TP53	0.986
HRAS	MAP2K2	0.986
NRAS	MAP2K1	0.986
YWHAZ	YWHAE	0.986
YWHAQ	SFN	0.985
AKT1	RHEB	0.985
RAP1A	BRAF	0.985
CBY1	YWHAE	0.985
YWHAB	YWHAG	0.985
MTOR	TSC1	0.9840000000000001
YWHAE	YWHAH	0.9840000000000001
PPP2CA	RPS6KB1	0.982
TP53	CDKN1B	0.982
MAP2K1	MAP2K2	0.982
DDIT4	TSC2	0.982
YWHAB	CDC25B	0.981
YWHAB	BRAF	0.98
NRAS	MAP2K2	0.98
RAP1A	ARAF	0.9790000000000001
CDC25C	YWHAG	0.9790000000000001
RAF1	YWHAH	0.9790000000000001
AKT1	RAF1	0.9790000000000001
FOXO3	YWHAZ	0.9790000000000001
YWHAB	TSC2	0.978
AKT1	SRC	0.978
YWHAZ	BRAF	0.978
AKT1S1	RPS6KB1	0.978
BAD	RAF1	0.977
YWHAZ	SFN	0.976
YWHAG	HDAC4	0.976
SFN	YWHAG	0.976
AKT1S1	YWHAH	0.975
YWHAQ	RAF1	0.9740000000000001
BRAF	YWHAE	0.973
CBY1	YWHAB	0.973
YWHAB	ARAF	0.973
CBY1	YWHAQ	0.972
AKT1	PPP2R1A	0.972
AKT1	YWHAZ	0.972
YWHAQ	BRAF	0.972
YWHAE	CDC25B	0.972
YWHAG	CDC25B	0.972
YWHAZ	BAD	0.972
AKT1S1	RHEB	0.972
YWHAZ	CDC25B	0.971
YWHAB	CDC25C	0.971
PPP2R1A	TP53	0.971
CDC25C	YWHAE	0.971
YWHAQ	CDC25B	0.971
CBY1	YWHAG	0.971
KSR1	RAF1	0.97
CBY1	YWHAH	0.97
YAP1	SRC	0.9690000000000001
SFN	CDC25C	0.968
YWHAB	SFN	0.968
DDIT4	TP53	0.968
SFN	CDC25B	0.9670000000000001
KSR1	BRAF	0.9670000000000001
HRAS	TP53	0.966
MARK3	KSR1	0.966
BAD	BCL2L11	0.965
PHB	RAF1	0.965
KSR2	BRAF	0.965
HRAS	KSR1	0.965
BAD	YWHAQ	0.9640000000000001
AKT1	SFN	0.9640000000000001
MAP2K1	PEBP1	0.963
PPP2CA	YWHAQ	0.963
KSR2	RAF1	0.961
YWHAG	RAF1	0.96
SFN	MST1R	0.96
FOXO3	YWHAB	0.96
CDC25C	YWHAH	0.96
SFN	RAF1	0.9590000000000001
YWHAZ	TSC2	0.9590000000000001
YWHAZ	TP53	0.9590000000000001
CBY1	AKT1	0.9590000000000001
YWHAB	HDAC4	0.9590000000000001
YWHAQ	CDC25C	0.9590000000000001
PPP2CA	RAF1	0.9590000000000001
HDAC4	YWHAE	0.958
SRC	RAF1	0.958
KSR1	NRAS	0.958
HRAS	PEBP1	0.958
YWHAE	HDAC5	0.958
YWHAH	CDC25B	0.958
KSR1	YWHAZ	0.958
MARK3	YWHAB	0.958
HRAS	KSR2	0.9570000000000001
AKT1	ITGB4	0.9570000000000001
FOXO3	YWHAE	0.9570000000000001
DDIT4	TSC1	0.9570000000000001
FOXO3	YWHAQ	0.9570000000000001
YWHAB	TSC1	0.9570000000000001
BRAF	YWHAH	0.956
SFN	BRAF	0.955
SRC	NRAS	0.955
PPP2CA	TP53	0.9540000000000001
HRAS	BCL2L11	0.9540000000000001
YWHAG	BRAF	0.9540000000000001
HRAS	ITGA6	0.9540000000000001
YWHAB	HDAC5	0.9540000000000001
YWHAZ	MTOR	0.9540000000000001
TP53	YWHAE	0.9540000000000001
BCL2L11	MAP2K1	0.9540000000000001
SRC	MAP2K1	0.953
PPP2CA	YWHAZ	0.953
YWHAQ	MTOR	0.953
BRAF	RAF1	0.9520000000000001
ARAF	BRAF	0.9520000000000001
KSR2	NRAS	0.9520000000000001
PPP2CA	MTOR	0.951
YWHAZ	TBC1D4	0.951
AKT1	YWHAE	0.951
PPP2CA	MAP2K1	0.95
YWHAG	TP53	0.95
YWHAZ	RAP1A	0.95
YWHAH	TSC2	0.95
PPP2CA	YWHAB	0.95
BCL2L11	SRC	0.95
YAP1	YWHAB	0.9490000000000001
HRAS	PPP2R1A	0.9490000000000001
AKT1	YWHAB	0.9490000000000001
YWHAQ	YWHAG	0.9490000000000001
YWHAB	PEBP1	0.9490000000000001
KSR1	ARAF	0.9490000000000001
PPP2CA	YWHAH	0.948
PPP2CA	YWHAG	0.948
MST1R	YWHAH	0.948
AKT1	YWHAQ	0.948
KSR1	YWHAE	0.948
YWHAB	TP53	0.9470000000000001
AKT1	MST1R	0.9470000000000001
YWHAG	MST1R	0.9470000000000001
YWHAB	MST1R	0.9470000000000001
YWHAQ	MST1R	0.9470000000000001
RPS6KB1	TSC2	0.9470000000000001
MST1R	YWHAE	0.9470000000000001
BAD	YWHAB	0.9470000000000001
YWHAZ	CDKN1B	0.9470000000000001
YWHAZ	MST1R	0.9470000000000001
YWHAQ	YWHAE	0.946
AKT1	YWHAG	0.946
BCL2L11	RAF1	0.946
KSR2	ARAF	0.946
YWHAB	MAP2K1	0.946
YWHAB	RHEB	0.946
YWHAB	MAP2K2	0.945
TP53	HDAC5	0.945
SRC	MAP2K2	0.9440000000000001
ITGA6	YWHAZ	0.9440000000000001
YWHAB	CDKN1B	0.9440000000000001
SRC	RAP1A	0.943
YWHAE	CDKN1B	0.943
YWHAE	TSC2	0.943
HRAS	YWHAZ	0.943
YWHAZ	TSC1	0.943
YWHAQ	TSC1	0.9420000000000001
RAN	YWHAQ	0.9420000000000001
TSC1	YWHAE	0.9420000000000001
HRAS	YWHAB	0.9420000000000001
AKT1	YWHAH	0.9420000000000001
RAN	YWHAE	0.9420000000000001
KSR1	YWHAH	0.9420000000000001
KSR1	PPP2CB	0.9420000000000001
SFN	TSC2	0.9420000000000001
KSR1	YWHAG	0.9420000000000001
YAP1	AKT1	0.941
SIK3	YWHAE	0.941
KSR2	YWHAB	0.941
SIK3	SFN	0.941
TBC1D4	YWHAB	0.941
YWHAH	HDAC5	0.941
SIK3	YWHAB	0.941
BAD	YWHAG	0.941
SIK3	YWHAH	0.941
YWHAQ	TSC2	0.941
YWHAQ	SIK3	0.941
YWHAZ	SIK3	0.941
ZFP36	YWHAB	0.941
KSR1	YWHAB	0.941
YWHAB	PPP2R1A	0.94
AKT1	ITGA6	0.94
YWHAG	TSC2	0.94
PHB	YWHAB	0.94
BCL2L11	NRAS	0.94
KSR1	PEBP1	0.94
TSC1	YWHAH	0.94
YWHAQ	CDKN1B	0.94
MAP2K1	YWHAE	0.94
PPP2CA	YWHAE	0.94
RAN	YWHAZ	0.9390000000000001
BCL2L11	BRAF	0.9390000000000001
BCL2L11	YWHAB	0.9390000000000001
HRAS	YWHAQ	0.9390000000000001
BAD	YWHAE	0.938
RAP1A	MAP2K1	0.938
YWHAZ	DDIT4	0.938
AKT1S1	YWHAB	0.938
PPP2R1A	RAF1	0.938
PHB	HRAS	0.938
BAD	SFN	0.938
YWHAB	PPP2CB	0.938
ARAF	PEBP1	0.938
YWHAG	CDKN1B	0.938
YWHAB	RAP1A	0.938
HRAS	YWHAE	0.938
ARAF	RAF1	0.938
YWHAQ	YWHAB	0.938
BRAF	PPP2CB	0.937
ITGA6	YWHAQ	0.9359999999999999
YWHAQ	ITGB4	0.9359999999999999
KSR1	YWHAQ	0.9359999999999999
YWHAB	MTOR	0.9359999999999999
YWHAB	DDIT4	0.9359999999999999
FOXO3	TP53	0.9359999999999999
HRAS	YWHAG	0.9359999999999999
YWHAZ	MAP2K1	0.9359999999999999
YWHAB	RPS6KB1	0.9359999999999999
ITGA6	YWHAG	0.9359999999999999
YWHAZ	NRAS	0.935
YWHAB	PPP5C	0.935
RAN	YWHAB	0.935
ITGA6	YWHAB	0.935
KSR1	SFN	0.935
FOXO3	YWHAH	0.935
ITGA6	YWHAE	0.934
YWHAB	ITGB4	0.934
YWHAZ	AKT1S1	0.934
AKT1S1	YWHAG	0.934
SRC	YWHAB	0.934
ITGA6	YWHAH	0.9329999999999999
MTOR	YWHAH	0.9329999999999999
YWHAH	CDKN1B	0.9329999999999999
YWHAQ	TP53	0.9329999999999999
BAD	YWHAH	0.9329999999999999
YWHAQ	YWHAH	0.9329999999999999
RAP1A	MAP2K2	0.9329999999999999
YWHAB	NRAS	0.9329999999999999
AKT1	PPP2CB	0.9329999999999999
MAP2K2	PEBP1	0.932
PPP2CA	HRAS	0.932
PPP2CA	SFN	0.932
HRAS	SFN	0.932
YWHAQ	PPP2R1A	0.9309999999999999
NRAS	YWHAE	0.9309999999999999
YWHAZ	YWHAQ	0.9309999999999999
RAF1	PPP2CB	0.9309999999999999
HRAS	YWHAH	0.9309999999999999
HDAC4	HDAC5	0.9309999999999999
FOXO3	YWHAG	0.93
PPP2CA	MAP2K2	0.93
NRAS	YWHAG	0.93
NRAS	YWHAH	0.929
YWHAQ	NRAS	0.929
YWHAE	MAP2K2	0.929
KSR1	RAP1A	0.929
TBC1D4	YWHAE	0.9279999999999999
ITGA6	SFN	0.9279999999999999
YWHAQ	TBC1D4	0.9279999999999999
MTOR	SFN	0.9279999999999999
PPP2CA	NRAS	0.927
PPP2R1A	YWHAG	0.927
PPP2CA	ARAF	0.927
KSR2	RAP1A	0.927
RAN	YWHAH	0.927
SFN	ITGB4	0.9259999999999999
AKT1	BCL2L11	0.9259999999999999
HRAS	PPP2CB	0.9259999999999999
ARAF	PPP2CB	0.9259999999999999
PPP2CA	KSR1	0.9259999999999999
SRC	ARAF	0.9259999999999999
PPP2CA	BRAF	0.9259999999999999
RPS6KB1	PPP2CB	0.9259999999999999
SRC	BRAF	0.9259999999999999
BCL2L11	MAP2K2	0.925
PHB	BRAF	0.925
SRC	PEBP1	0.925
BRAF	PEBP1	0.925
BCL2L11	ARAF	0.924
SFN	MAP2K2	0.9229999999999999
NRAS	PPP2CB	0.9229999999999999
MTOR	YWHAG	0.9229999999999999
AKT1S1	YWHAQ	0.9229999999999999
SFN	TSC1	0.922
HRAS	ITGB4	0.922
PPP2R1A	YWHAE	0.922
MTOR	YWHAE	0.922
RAN	YWHAG	0.922
RAP1A	NRAS	0.9209999999999999
HRAS	RAP1A	0.9209999999999999
RAN	SFN	0.9209999999999999
PPP2R1A	YWHAH	0.9209999999999999
RAF1	PPP5C	0.92
KSR1	SRC	0.92
MARK3	HRAS	0.919
ARAF	PPP5C	0.919
SIK3	YWHAG	0.919
YWHAZ	PPP2R1A	0.919
PPP2R1A	MAP2K2	0.9179999999999999
NRAS	PEBP1	0.917
MARK3	RAF1	0.917
PPP2R1A	MAP2K1	0.917
PHB	NRAS	0.917
HRAS	PPP5C	0.917
YWHAG	TSC1	0.9159999999999999
NRAS	SFN	0.9159999999999999
NRAS	PPP5C	0.915
TBC1D4	YWHAH	0.915
CDC25C	CDC25B	0.915
KSR1	BCL2L11	0.915
BRAF	PPP5C	0.9129999999999999
YWHAG	MAP2K1	0.9129999999999999
TP53	YWHAH	0.912
KSR1	PPP5C	0.912
SFN	CDKN1B	0.912
MARK3	ARAF	0.9109999999999999
YWHAZ	ITGB4	0.91
KSR2	PEBP1	0.91
TBC1D4	YWHAG	0.91
PPP2R1A	ARAF	0.91
MARK3	PPP2CB	0.91
PHB	ARAF	0.909
PPP2R1A	BRAF	0.909
AKT1S1	YWHAE	0.909
KSR2	SRC	0.909
SFN	DDIT4	0.909
MARK3	KSR2	0.909
TP53	PPP2CB	0.909
MARK3	SRC	0.909
MARK3	MAP2K1	0.9079999999999999
MARK3	BRAF	0.9079999999999999
YWHAQ	MAP2K1	0.9079999999999999
FOXO3	SFN	0.9079999999999999
YWHAG	MAP2K2	0.907
ITGA6	RPS6KB1	0.907
TSC1	PPP5C	0.907
YWHAH	ITGB4	0.907
SFN	PPP2R1A	0.9059999999999999
YWHAG	ITGB4	0.9059999999999999
BCL2L11	PEBP1	0.9059999999999999
PHB	KSR1	0.9059999999999999
MAP2K1	YWHAH	0.9059999999999999
KSR2	BCL2L11	0.9059999999999999
YWHAZ	MAP2K2	0.905
MARK3	MAP2K2	0.905
YWHAQ	MAP2K2	0.905
KSR1	PPP2R1A	0.904
TBC1D4	SFN	0.904
YWHAE	ITGB4	0.904
KSR2	KSR1	0.904
AKT1S1	SFN	0.904
YWHAQ	DDIT4	0.903
NRAS	PPP2R1A	0.903
RAN	HDAC4	0.903
MARK3	RAP1A	0.903
MAP2K2	YWHAH	0.903
SFN	YWHAE	0.902
PPP2CA	MARK3	0.902
RAP1A	PEBP1	0.902
SFN	MAP2K1	0.902
AKT1	HRAS	0.9009999999999999
MARK3	PEBP1	0.9009999999999999
RAN	FOXO3	0.9009999999999999
DDIT4	YWHAE	0.9009999999999999
SFN	YWHAH	0.9009999999999999
DDIT4	YWHAG	0.9
MARK3	NRAS	0.9
MARK3	PPP2R1A	0.9
MARK3	BCL2L11	0.9
BCL2L11	RAP1A	0.9
DDIT4	YWHAH	0.9

Gene Ontology Semantic Similarity

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#	5604 (MAP2K1)	207 (AKT1)	3265 (HRAS)	5518 (PPP2R1A)	7248 (TSC1)	2475 (MTOR)	5515 (PPP2CA)	7534 (YWHAZ)	6009 (RHEB)	84335 (AKT1S1)	5906 (RAP1A)	283455 (KSR2)	25776 (CBY1)	7529 (YWHAB)	7532 (YWHAG)	4893 (NRAS)	8844 (KSR1)	673 (BRAF)	2309 (FOXO3)	369 (ARAF)	995 (CDC25C)	5037 (PEBP1)	5605 (MAP2K2)	3655 (ITGA6)	7531 (YWHAE)	2810 (SFN)	10971 (YWHAQ)	7157 (TP53)	5894 (RAF1)	572 (BAD)	10413 (YAP1)	4140 (MARK3)	5245 (PHB)	9759 (HDAC4)	6714 (SRC)	7533 (YWHAH)	10018 (BCL2L11)	4486 (MST1R)	6198 (RPS6KB1)	5901 (RAN)	23387 (SIK3)	9882 (TBC1D4)	7538 (ZFP36)	5516 (PPP2CB)	7249 (TSC2)	1027 (CDKN1B)	3691 (ITGB4)	994 (CDC25B)	10014 (HDAC5)	5536 (PPP5C)
5604 (MAP2K1)	1.00	0.75	0.43	0.48	0.53	0.72	1.00	0.54	0.19	1.00	0.43	0.60	0.51	0.54	0.47	0.71	0.78	0.81	0.42	0.84	0.43	0.47	0.94	0.49	0.50	0.50	0.51	0.49	0.83	0.47	0.43	0.80	0.55	0.46	0.77	0.53	0.45	0.63	0.86	0.39	0.72	0.27	0.49	0.41	0.50	0.54	0.49	0.41	0.47	0.44
207 (AKT1)	0.75	1.00	0.54	0.51	0.50	0.68	1.00	0.57	0.33	1.00	0.46	0.48	0.54	0.57	0.48	0.71	0.69	0.73	0.44	0.73	0.46	0.56	0.73	0.50	0.55	0.52	0.48	0.56	0.80	0.56	0.44	0.69	0.55	0.48	0.75	0.56	0.46	0.61	0.79	0.48	0.75	0.28	0.54	0.44	0.53	0.50	0.50	0.45	0.50	0.58
3265 (HRAS)	0.43	0.54	1.00	0.53	0.61	0.42	1.00	0.63	0.78	1.00	0.49	0.21	0.61	0.64	0.52	0.71	0.54	0.45	0.47	0.42	0.51	0.56	0.42	0.58	0.55	0.54	0.58	0.55	0.47	0.52	0.49	0.48	0.63	0.51	0.60	0.60	0.54	0.52	0.39	0.68	0.64	0.25	0.55	0.50	0.53	0.47	0.58	0.49	0.53	0.65
5518 (PPP2R1A)	0.48	0.51	0.53	1.00	0.73	0.46	1.00	0.68	0.23	1.00	0.59	0.27	0.72	0.70	0.60	0.71	0.58	0.51	0.50	0.49	0.56	0.62	0.49	0.68	0.64	0.67	0.71	0.54	0.52	0.62	0.61	0.60	0.66	0.52	0.60	0.74	0.66	0.62	0.45	0.48	0.51	0.39	0.58	0.60	0.66	0.58	0.68	0.54	0.55	0.50
7248 (TSC1)	0.53	0.50	0.61	0.73	1.00	0.51	1.00	0.76	0.25	1.00	0.68	0.27	0.84	0.78	0.67	0.71	0.67	0.57	0.56	0.57	0.65	0.72	0.53	0.80	0.63	0.75	0.96	0.56	0.58	0.67	0.63	0.75	0.74	0.56	0.64	0.74	0.83	0.76	0.53	0.48	0.61	0.38	0.64	0.75	0.71	0.58	0.80	0.64	0.61	0.55
2475 (MTOR)	0.72	0.68	0.42	0.46	0.51	1.00	1.00	0.59	0.20	1.00	0.43	0.47	0.52	0.58	0.50	0.71	0.67	0.71	0.56	0.72	0.45	0.53	0.69	0.50	0.55	0.47	0.49	0.57	0.76	0.45	0.58	0.70	0.66	0.62	0.75	0.53	0.46	0.58	0.78	0.43	0.63	0.21	0.54	0.43	0.47	0.44	0.50	0.43	0.64	0.43
5515 (PPP2CA)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.36	1.00	1.00	0.34	1.00	1.00	1.00	0.71	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.49	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00
7534 (YWHAZ)	0.54	0.57	0.63	0.68	0.76	0.59	1.00	1.00	0.26	1.00	0.65	0.25	0.79	0.79	0.79	0.71	0.66	0.65	0.72	0.63	0.70	0.85	0.55	0.78	0.77	0.78	0.75	0.67	0.66	0.71	0.67	0.68	0.74	0.67	0.70	0.74	0.72	0.72	0.56	0.63	0.62	0.36	0.84	0.68	0.68	0.64	0.72	0.70	0.72	0.61
6009 (RHEB)	0.19	0.33	0.78	0.23	0.25	0.20	0.36	0.26	1.00	0.36	0.21	0.15	0.24	0.27	0.23	0.25	0.22	0.28	0.23	0.19	0.23	0.27	0.19	0.23	0.23	0.22	0.24	0.29	0.21	0.27	0.21	0.21	0.24	0.32	0.24	0.23	0.22	0.22	0.20	0.56	0.62	0.10	0.24	0.24	0.21	0.19	0.23	0.23	0.25	0.44
84335 (AKT1S1)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.36	1.00	1.00	0.34	1.00	1.00	1.00	0.71	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.49	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00
5906 (RAP1A)	0.43	0.46	0.49	0.59	0.68	0.43	1.00	0.65	0.21	1.00	1.00	0.26	0.67	0.67	0.54	1.00	0.55	0.47	0.48	0.45	0.52	0.58	0.44	0.64	0.64	0.60	0.65	0.51	0.49	0.54	0.51	0.54	0.63	0.50	0.60	0.66	0.64	0.57	0.41	0.47	0.47	0.32	0.56	0.54	0.59	0.55	0.64	0.50	0.53	0.47
283455 (KSR2)	0.60	0.48	0.21	0.27	0.27	0.47	0.34	0.25	0.15	0.34	0.26	1.00	0.26	0.25	0.23	0.24	0.68	0.55	0.23	0.63	0.23	0.24	0.54	0.25	0.24	0.25	0.27	0.22	0.57	0.25	0.24	0.62	0.24	0.22	0.40	0.26	0.25	0.42	0.75	0.22	0.46	0.15	0.23	0.25	0.24	0.28	0.25	0.23	0.23	0.36
25776 (CBY1)	0.51	0.54	0.61	0.72	0.84	0.52	1.00	0.79	0.24	1.00	0.67	0.26	1.00	0.77	0.66	0.71	0.66	0.62	0.59	0.57	0.64	0.71	0.53	0.78	0.63	0.80	0.84	0.56	0.62	0.66	0.63	0.73	0.73	0.57	0.64	0.73	0.79	0.73	0.54	0.49	0.61	0.36	0.63	0.73	0.79	0.58	0.78	0.64	0.61	0.60
7529 (YWHAB)	0.54	0.57	0.64	0.70	0.78	0.58	1.00	0.79	0.27	1.00	0.67	0.25	0.77	1.00	0.67	0.71	0.67	0.60	0.59	0.60	0.67	0.75	0.57	0.80	0.79	0.77	0.78	0.60	0.64	0.67	0.63	0.71	0.78	0.61	0.71	0.78	0.75	0.76	0.57	0.55	0.63	0.40	0.68	0.71	0.72	0.61	0.75	0.66	0.66	0.59
7532 (YWHAG)	0.47	0.48	0.52	0.60	0.67	0.50	1.00	0.79	0.23	1.00	0.54	0.23	0.66	0.67	1.00	0.71	0.55	0.52	0.64	0.51	0.59	0.77	0.49	0.63	0.64	0.79	0.65	0.59	0.53	0.62	0.56	0.55	0.67	0.57	0.62	0.70	0.60	0.59	0.43	0.54	0.49	0.33	0.79	0.55	0.60	0.70	0.64	0.58	0.64	0.49
4893 (NRAS)	0.71	0.71	0.71	0.71	0.71	0.71	0.71	0.71	0.25	0.71	1.00	0.24	0.71	0.71	0.71	1.00	0.71	0.71	0.71	0.71	0.71	0.71	0.71	0.71	0.72	0.71	0.71	0.71	0.71	0.71	0.71	0.71	0.71	0.71	0.72	0.71	0.74	0.71	0.71	0.71	0.71	0.35	0.71	0.71	0.71	1.00	0.71	0.71	0.71	0.71
8844 (KSR1)	0.78	0.69	0.54	0.58	0.67	0.67	1.00	0.66	0.22	1.00	0.55	0.68	0.66	0.67	0.55	0.71	1.00	0.74	0.50	0.77	0.55	0.60	0.72	0.64	0.58	0.60	0.65	0.52	0.78	0.56	0.53	0.77	0.67	0.52	0.76	0.65	0.61	0.70	0.81	0.45	0.65	0.30	0.57	0.56	0.58	0.57	0.64	0.53	0.55	0.59
673 (BRAF)	0.81	0.73	0.45	0.51	0.57	0.71	1.00	0.65	0.28	1.00	0.47	0.55	0.62	0.60	0.52	0.71	0.74	1.00	0.49	0.93	0.53	0.57	0.78	0.55	0.53	0.55	0.55	0.55	0.93	0.54	0.47	0.81	0.58	0.53	0.76	0.58	0.51	0.67	0.84	0.45	0.78	0.25	0.56	0.47	0.52	0.53	0.55	0.51	0.53	0.48
2309 (FOXO3)	0.42	0.44	0.47	0.50	0.56	0.56	1.00	0.72	0.23	1.00	0.48	0.23	0.59	0.59	0.64	0.71	0.50	0.49	1.00	0.47	0.53	0.69	0.43	0.54	0.60	0.52	0.54	0.73	0.50	0.54	0.62	0.47	0.70	0.67	0.60	0.57	0.51	0.51	0.41	0.52	0.45	0.25	0.69	0.47	0.51	0.52	0.54	0.52	0.68	0.46
369 (ARAF)	0.84	0.73	0.42	0.49	0.57	0.72	1.00	0.63	0.19	1.00	0.45	0.63	0.57	0.60	0.51	0.71	0.77	0.93	0.47	1.00	0.51	0.57	0.81	0.55	0.53	0.51	0.54	0.51	0.95	0.52	0.45	0.88	0.58	0.47	0.77	0.58	0.49	0.69	0.89	0.39	0.74	0.24	0.55	0.44	0.50	0.52	0.55	0.50	0.52	0.44
995 (CDC25C)	0.43	0.46	0.51	0.56	0.65	0.45	1.00	0.70	0.23	1.00	0.52	0.23	0.64	0.67	0.59	0.71	0.55	0.53	0.53	0.51	1.00	0.65	0.44	0.62	0.56	0.58	0.63	0.54	0.54	0.61	0.51	0.53	0.63	0.53	0.61	0.65	0.58	0.57	0.43	0.44	0.47	0.28	0.60	0.83	0.56	0.55	0.62	0.97	0.61	0.71
5037 (PEBP1)	0.47	0.56	0.56	0.62	0.72	0.53	1.00	0.85	0.27	1.00	0.58	0.24	0.71	0.75	0.77	0.71	0.60	0.57	0.69	0.57	0.65	1.00	0.48	0.68	0.69	0.64	0.71	0.64	0.60	0.77	0.60	0.61	0.75	0.60	0.65	0.70	0.66	0.69	0.47	0.56	0.54	0.36	0.86	0.61	0.65	0.60	0.68	0.64	0.66	0.52
5605 (MAP2K2)	0.94	0.73	0.42	0.49	0.53	0.69	1.00	0.55	0.19	1.00	0.44	0.54	0.53	0.57	0.49	0.71	0.72	0.78	0.43	0.81	0.44	0.48	1.00	0.51	0.51	0.52	0.50	0.49	0.80	0.48	0.44	0.78	0.54	0.46	0.74	0.56	0.47	0.62	0.83	0.39	0.69	0.28	0.50	0.43	0.52	0.55	0.51	0.42	0.48	0.45
3655 (ITGA6)	0.49	0.50	0.58	0.68	0.80	0.50	1.00	0.78	0.23	1.00	0.64	0.25	0.78	0.80	0.63	0.71	0.64	0.55	0.54	0.55	0.62	0.68	0.51	1.00	0.65	0.78	0.80	0.53	0.56	0.63	0.60	0.69	0.71	0.55	0.65	0.71	0.75	0.70	0.51	0.51	0.58	0.34	0.62	0.69	0.67	0.56	0.92	0.61	0.59	0.53
7531 (YWHAE)	0.50	0.55	0.55	0.64	0.63	0.55	1.00	0.77	0.23	1.00	0.64	0.24	0.63	0.79	0.64	0.72	0.58	0.53	0.60	0.53	0.56	0.69	0.51	0.65	1.00	0.63	0.61	0.64	0.57	0.58	0.60	0.57	0.69	0.60	0.67	0.76	0.60	0.62	0.50	0.60	0.54	0.35	0.73	0.57	0.61	0.57	0.61	0.56	0.61	0.54
2810 (SFN)	0.50	0.52	0.54	0.67	0.75	0.47	1.00	0.78	0.22	1.00	0.60	0.25	0.80	0.77	0.79	0.71	0.60	0.55	0.52	0.51	0.58	0.64	0.52	0.78	0.63	1.00	0.74	0.53	0.56	0.61	0.56	0.62	0.68	0.53	0.64	0.69	0.69	0.65	0.47	0.49	0.53	0.36	0.59	0.62	0.67	0.70	0.70	0.56	0.56	0.54
10971 (YWHAQ)	0.51	0.48	0.58	0.71	0.96	0.49	1.00	0.75	0.24	1.00	0.65	0.27	0.84	0.78	0.65	0.71	0.65	0.55	0.54	0.54	0.63	0.71	0.50	0.80	0.61	0.74	1.00	0.54	0.56	0.65	0.60	0.74	0.73	0.55	0.63	0.73	0.83	0.74	0.49	0.46	0.57	0.38	0.62	0.74	0.69	0.56	0.80	0.61	0.59	0.53
7157 (TP53)	0.49	0.56	0.55	0.54	0.56	0.57	1.00	0.67	0.29	1.00	0.51	0.22	0.56	0.60	0.59	0.71	0.52	0.55	0.73	0.51	0.54	0.64	0.49	0.53	0.64	0.53	0.54	1.00	0.56	0.54	0.63	0.51	0.67	0.69	0.60	0.59	0.52	0.56	0.48	0.63	0.57	0.28	0.67	0.51	0.55	0.56	0.54	0.53	0.66	0.57
5894 (RAF1)	0.83	0.80	0.47	0.52	0.58	0.76	1.00	0.66	0.21	1.00	0.49	0.57	0.62	0.64	0.53	0.71	0.78	0.93	0.50	0.95	0.54	0.60	0.80	0.56	0.57	0.56	0.56	0.56	1.00	0.54	0.48	0.85	0.62	0.51	0.81	0.61	0.53	0.72	0.91	0.42	0.75	0.29	0.59	0.49	0.56	0.54	0.56	0.53	0.56	0.50
572 (BAD)	0.47	0.56	0.52	0.62	0.67	0.45	1.00	0.71	0.27	1.00	0.54	0.25	0.66	0.67	0.62	0.71	0.56	0.54	0.54	0.52	0.61	0.77	0.48	0.63	0.58	0.61	0.65	0.54	0.54	1.00	0.52	0.55	0.64	0.51	0.61	0.65	0.60	0.59	0.43	0.45	0.50	0.38	0.61	0.55	0.63	0.70	0.63	0.60	0.57	0.49
10413 (YAP1)	0.43	0.44	0.49	0.61	0.63	0.58	1.00	0.67	0.21	1.00	0.51	0.24	0.63	0.63	0.56	0.71	0.53	0.47	0.62	0.45	0.51	0.60	0.44	0.60	0.60	0.56	0.60	0.63	0.48	0.52	1.00	0.52	0.71	0.66	0.58	0.65	0.57	0.55	0.42	0.60	0.47	0.26	0.60	0.52	0.55	0.49	0.60	0.49	0.66	0.47
4140 (MARK3)	0.80	0.69	0.48	0.60	0.75	0.70	1.00	0.68	0.21	1.00	0.54	0.62	0.73	0.71	0.55	0.71	0.77	0.81	0.47	0.88	0.53	0.61	0.78	0.69	0.57	0.62	0.74	0.51	0.85	0.55	0.52	1.00	0.66	0.51	0.75	0.67	0.66	0.76	0.91	0.42	0.75	0.30	0.57	0.56	0.60	0.49	0.69	0.50	0.54	0.46
5245 (PHB)	0.55	0.55	0.63	0.66	0.74	0.66	1.00	0.74	0.24	1.00	0.63	0.24	0.73	0.78	0.67	0.71	0.67	0.58	0.70	0.58	0.63	0.75	0.54	0.71	0.69	0.68	0.73	0.67	0.62	0.64	0.71	0.66	1.00	0.71	0.67	0.72	0.70	0.72	0.54	0.53	0.60	0.36	0.71	0.66	0.68	0.59	0.74	0.62	0.76	0.56
9759 (HDAC4)	0.46	0.48	0.51	0.52	0.56	0.62	1.00	0.67	0.32	1.00	0.50	0.22	0.57	0.61	0.57	0.71	0.52	0.53	0.67	0.47	0.53	0.60	0.46	0.55	0.60	0.53	0.55	0.69	0.51	0.51	0.66	0.51	0.71	1.00	0.59	0.58	0.53	0.53	0.47	0.55	0.53	0.25	0.62	0.53	0.53	0.49	0.55	0.53	0.90	0.51
6714 (SRC)	0.77	0.75	0.60	0.60	0.64	0.75	1.00	0.70	0.24	1.00	0.60	0.40	0.64	0.71	0.62	0.72	0.76	0.76	0.60	0.77	0.61	0.65	0.74	0.65	0.67	0.64	0.63	0.60	0.81	0.61	0.58	0.75	0.67	0.59	1.00	0.68	0.62	0.72	0.80	0.56	0.71	0.31	0.65	0.60	0.62	0.59	0.64	0.60	0.62	0.57
7533 (YWHAH)	0.53	0.56	0.60	0.74	0.74	0.53	1.00	0.74	0.23	1.00	0.66	0.26	0.73	0.78	0.70	0.71	0.65	0.58	0.57	0.58	0.65	0.70	0.56	0.71	0.76	0.69	0.73	0.59	0.61	0.65	0.65	0.67	0.72	0.58	0.68	1.00	0.70	0.71	0.55	0.55	0.60	0.38	0.65	0.67	0.70	0.61	0.71	0.63	0.62	0.56
10018 (BCL2L11)	0.45	0.46	0.54	0.66	0.83	0.46	1.00	0.72	0.22	1.00	0.64	0.25	0.79	0.75	0.60	0.74	0.61	0.51	0.51	0.49	0.58	0.66	0.47	0.75	0.60	0.69	0.83	0.52	0.53	0.60	0.57	0.66	0.70	0.53	0.62	0.70	1.00	0.68	0.44	0.44	0.52	0.34	0.60	0.66	0.65	0.55	0.75	0.56	0.56	0.49
4486 (MST1R)	0.63	0.61	0.52	0.62	0.76	0.58	1.00	0.72	0.22	1.00	0.57	0.42	0.73	0.76	0.59	0.71	0.70	0.67	0.51	0.69	0.57	0.69	0.62	0.70	0.62	0.65	0.74	0.56	0.72	0.59	0.55	0.76	0.72	0.53	0.72	0.71	0.68	1.00	0.67	0.44	0.61	0.37	0.63	0.61	0.66	0.54	0.70	0.56	0.58	0.50
6198 (RPS6KB1)	0.86	0.79	0.39	0.45	0.53	0.78	1.00	0.56	0.20	1.00	0.41	0.75	0.54	0.57	0.43	0.71	0.81	0.84	0.41	0.89	0.43	0.47	0.83	0.51	0.50	0.47	0.49	0.48	0.91	0.43	0.42	0.91	0.54	0.47	0.80	0.55	0.44	0.67	1.00	0.38	0.76	0.21	0.50	0.40	0.46	0.42	0.51	0.40	0.49	0.41
5901 (RAN)	0.39	0.48	0.68	0.48	0.48	0.43	1.00	0.63	0.56	1.00	0.47	0.22	0.49	0.55	0.54	0.71	0.45	0.45	0.52	0.39	0.44	0.56	0.39	0.51	0.60	0.49	0.46	0.63	0.42	0.45	0.60	0.42	0.53	0.55	0.56	0.55	0.44	0.44	0.38	1.00	0.57	0.20	0.63	0.42	0.45	0.43	0.47	0.42	0.50	0.54
23387 (SIK3)	0.72	0.75	0.64	0.51	0.61	0.63	1.00	0.62	0.62	1.00	0.47	0.46	0.61	0.63	0.49	0.71	0.65	0.78	0.45	0.74	0.47	0.54	0.69	0.58	0.54	0.53	0.57	0.57	0.75	0.50	0.47	0.75	0.60	0.53	0.71	0.60	0.52	0.61	0.76	0.57	1.00	0.24	0.54	0.46	0.52	0.46	0.58	0.44	0.50	0.63
9882 (TBC1D4)	0.27	0.28	0.25	0.39	0.38	0.21	0.49	0.36	0.10	0.49	0.32	0.15	0.36	0.40	0.33	0.35	0.30	0.25	0.25	0.24	0.28	0.36	0.28	0.34	0.35	0.36	0.38	0.28	0.29	0.38	0.26	0.30	0.36	0.25	0.31	0.38	0.34	0.37	0.21	0.20	0.24	1.00	0.31	0.30	0.68	0.36	0.34	0.28	0.28	0.24
7538 (ZFP36)	0.49	0.54	0.55	0.58	0.64	0.54	1.00	0.84	0.24	1.00	0.56	0.23	0.63	0.68	0.79	0.71	0.57	0.56	0.69	0.55	0.60	0.86	0.50	0.62	0.73	0.59	0.62	0.67	0.59	0.61	0.60	0.57	0.71	0.62	0.65	0.65	0.60	0.63	0.50	0.63	0.54	0.31	1.00	0.57	0.60	0.58	0.62	0.60	0.64	0.53
5516 (PPP2CB)	0.41	0.44	0.50	0.60	0.75	0.43	1.00	0.68	0.24	1.00	0.54	0.25	0.73	0.71	0.55	0.71	0.56	0.47	0.47	0.44	0.83	0.61	0.43	0.69	0.57	0.62	0.74	0.51	0.49	0.55	0.52	0.56	0.66	0.53	0.60	0.67	0.66	0.61	0.40	0.42	0.46	0.30	0.57	1.00	0.60	0.49	0.69	0.85	0.57	0.70
7249 (TSC2)	0.50	0.53	0.53	0.66	0.71	0.47	1.00	0.68	0.21	1.00	0.59	0.24	0.79	0.72	0.60	0.71	0.58	0.52	0.51	0.50	0.56	0.65	0.52	0.67	0.61	0.67	0.69	0.55	0.56	0.63	0.55	0.60	0.68	0.53	0.62	0.70	0.65	0.66	0.46	0.45	0.52	0.68	0.60	0.60	1.00	0.62	0.67	0.55	0.56	0.51
1027 (CDKN1B)	0.54	0.50	0.47	0.58	0.58	0.44	1.00	0.64	0.19	1.00	0.55	0.28	0.58	0.61	0.70	1.00	0.57	0.53	0.52	0.52	0.55	0.60	0.55	0.56	0.57	0.70	0.56	0.56	0.54	0.70	0.49	0.49	0.59	0.49	0.59	0.61	0.55	0.54	0.42	0.43	0.46	0.36	0.58	0.49	0.62	1.00	0.56	0.54	0.54	0.50
3691 (ITGB4)	0.49	0.50	0.58	0.68	0.80	0.50	1.00	0.72	0.23	1.00	0.64	0.25	0.78	0.75	0.64	0.71	0.64	0.55	0.54	0.55	0.62	0.68	0.51	0.92	0.61	0.70	0.80	0.54	0.56	0.63	0.60	0.69	0.74	0.55	0.64	0.71	0.75	0.70	0.51	0.47	0.58	0.34	0.62	0.69	0.67	0.56	1.00	0.61	0.59	0.53
994 (CDC25B)	0.41	0.45	0.49	0.54	0.64	0.43	1.00	0.70	0.23	1.00	0.50	0.23	0.64	0.66	0.58	0.71	0.53	0.51	0.52	0.50	0.97	0.64	0.42	0.61	0.56	0.56	0.61	0.53	0.53	0.60	0.49	0.50	0.62	0.53	0.60	0.63	0.56	0.56	0.40	0.42	0.44	0.28	0.60	0.85	0.55	0.54	0.61	1.00	0.60	0.71
10014 (HDAC5)	0.47	0.50	0.53	0.55	0.61	0.64	1.00	0.72	0.25	1.00	0.53	0.23	0.61	0.66	0.64	0.71	0.55	0.53	0.68	0.52	0.61	0.66	0.48	0.59	0.61	0.56	0.59	0.66	0.56	0.57	0.66	0.54	0.76	0.90	0.62	0.62	0.56	0.58	0.49	0.50	0.50	0.28	0.64	0.57	0.56	0.54	0.59	0.60	1.00	0.52
5536 (PPP5C)	0.44	0.58	0.65	0.50	0.55	0.43	1.00	0.61	0.44	1.00	0.47	0.36	0.60	0.59	0.49	0.71	0.59	0.48	0.46	0.44	0.71	0.52	0.45	0.53	0.54	0.54	0.53	0.57	0.50	0.49	0.47	0.46	0.56	0.51	0.57	0.56	0.49	0.50	0.41	0.54	0.63	0.24	0.53	0.70	0.51	0.50	0.53	0.71	0.52	1.00

Association with High Altitude

Protein Official symbol	Source Organism	Tissue of Expression	Level of hypoxia	Altitude	Duration of experiment	Level of expression	Fold change	Experiment details	geographical location	ethnicity of the patients	Control group	Control (Fold change)	Reference (PMID)
YWHAB	Human	Skeletal muscle	-	4559 m	9 day	downregulated	-1.14	2-DIGE	Southern Europe	Italians	1	Fasting control subjects at laboratory in Copenhagen with no caffeine intake	18937252

Association with TF

TF	TF Entrez	Gene	Gene Entrez	Type	PMID	Database

Association with miRNA

miRTarBase ID	miRNA	Species (miRNA)	Protein Official Symbol	Human Entrez ID	Species (Target Gene)	Experiments	Support Type	References (PMID)
MIRT035990	hsa-miR-1301-3p	Homo sapiens	YWHAB	7529	Homo sapiens	CLASH	Functional MTI (Weak)	23622248
MIRT037014	hsa-miR-877-3p	Homo sapiens	YWHAB	7529	Homo sapiens	CLASH	Functional MTI (Weak)	23622248
MIRT044012	hsa-miR-378a-5p	Homo sapiens	YWHAB	7529	Homo sapiens	CLASH	Functional MTI (Weak)	23622248
MIRT046917	hsa-miR-221-3p	Homo sapiens	YWHAB	7529	Homo sapiens	CLASH	Functional MTI (Weak)	23622248
MIRT439267	hsa-miR-218-5p	Homo sapiens	YWHAB	7529	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23212916
MIRT505098	hsa-miR-513a-3p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT505099	hsa-miR-3606-3p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT505100	hsa-miR-551b-5p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT505096	hsa-miR-5094	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT505103	hsa-miR-152-3p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT505101	hsa-miR-148b-3p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT505097	hsa-miR-513c-3p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT505102	hsa-miR-148a-3p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT505095	hsa-miR-6758-3p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT505094	hsa-miR-627-3p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT529367	hsa-miR-504-3p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT529360	hsa-miR-1270	Homo sapiens	YWHAB	7529	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	21572407
MIRT529361	hsa-miR-4423-5p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT529365	hsa-miR-3652	Homo sapiens	YWHAB	7529	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	21572407
MIRT529370	hsa-miR-6088	Homo sapiens	YWHAB	7529	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	21572407
MIRT529363	hsa-miR-143-5p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT529370	hsa-miR-6088	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT529366	hsa-miR-122-5p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT529362	hsa-miR-6501-5p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT529365	hsa-miR-3652	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT529371	hsa-miR-4770	Homo sapiens	YWHAB	7529	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	21572407
MIRT529360	hsa-miR-1270	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT529369	hsa-miR-3135b	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT529372	hsa-miR-143-3p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT529364	hsa-miR-4430	Homo sapiens	YWHAB	7529	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	21572407
MIRT529373	hsa-miR-4781-3p	Homo sapiens	YWHAB	7529	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	21572407
MIRT529359	hsa-miR-620	Homo sapiens	YWHAB	7529	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	21572407
MIRT529362	hsa-miR-6501-5p	Homo sapiens	YWHAB	7529	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	21572407
MIRT529364	hsa-miR-4430	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT529359	hsa-miR-620	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT529369	hsa-miR-3135b	Homo sapiens	YWHAB	7529	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	21572407
MIRT529358	hsa-miR-744-3p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT529361	hsa-miR-4423-5p	Homo sapiens	YWHAB	7529	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	21572407
MIRT529371	hsa-miR-4770	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT529373	hsa-miR-4781-3p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT529366	hsa-miR-122-5p	Homo sapiens	YWHAB	7529	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	21572407
MIRT529367	hsa-miR-504-3p	Homo sapiens	YWHAB	7529	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	21572407
MIRT529368	hsa-miR-4683	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT529368	hsa-miR-4683	Homo sapiens	YWHAB	7529	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	21572407
MIRT529372	hsa-miR-143-3p	Homo sapiens	YWHAB	7529	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	21572407
MIRT529358	hsa-miR-744-3p	Homo sapiens	YWHAB	7529	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	21572407
MIRT529363	hsa-miR-143-5p	Homo sapiens	YWHAB	7529	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	21572407
MIRT641784	hsa-miR-4457	Homo sapiens	YWHAB	7529	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	27418678
MIRT641784	hsa-miR-4457	Homo sapiens	YWHAB	7529	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	28735896
MIRT641784	hsa-miR-4457	Homo sapiens	YWHAB	7529	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23824327
MIRT641784	hsa-miR-4457	Homo sapiens	YWHAB	7529	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	19536157
MIRT706790	hsa-miR-7850-5p	Homo sapiens	YWHAB	7529	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	21572407
MIRT706791	hsa-miR-4531	Homo sapiens	YWHAB	7529	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	21572407
MIRT761654	hsa-miR-1255a	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	27292025
MIRT761663	hsa-miR-1255b-5p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	27292025
MIRT762101	hsa-miR-1273h-5p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	27292025
MIRT763253	hsa-miR-1909-5p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	27292025
MIRT764731	hsa-miR-30c-2-3p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	27292025
MIRT764639	hsa-miR-30b-3p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	27292025
MIRT764686	hsa-miR-30c-1-3p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	27292025
MIRT766075	hsa-miR-3614-5p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	27292025
MIRT766462	hsa-miR-3663-3p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	27292025
MIRT766457	hsa-miR-3661	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	27292025
MIRT766867	hsa-miR-3689a-3p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	27292025
MIRT766955	hsa-miR-3689b-3p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	27292025
MIRT767043	hsa-miR-3689c	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	27292025
MIRT768482	hsa-miR-4299	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	27292025
MIRT768242	hsa-miR-4269	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	27292025
MIRT768651	hsa-miR-4325	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	27292025
MIRT773980	hsa-miR-542-3p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	27292025
MIRT774723	hsa-miR-5582-5p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	27292025
MIRT776045	hsa-miR-619-3p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	27292025
MIRT776135	hsa-miR-631	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	27292025
MIRT777696	hsa-miR-6715b-5p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	27292025
MIRT778188	hsa-miR-6744-5p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	27292025
MIRT777987	hsa-miR-6731-5p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	27292025
MIRT779035	hsa-miR-6780a-5p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	27292025
MIRT778945	hsa-miR-6779-5p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	27292025
MIRT779263	hsa-miR-6788-5p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	27292025
MIRT780780	hsa-miR-6878-5p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	27292025
MIRT781971	hsa-miR-769-5p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	27292025
MIRT782430	hsa-miR-8085	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	27292025
MIRT782581	hsa-miR-887-5p	Homo sapiens	YWHAB	7529	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	27292025
MIRT783740	hsa-miR-130b-5p	Homo sapiens	YWHAB	7529	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	28735896
MIRT783740	hsa-miR-130b-5p	Homo sapiens	YWHAB	7529	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	27418678
MIRT786616	hsa-miR-4753-3p	Homo sapiens	YWHAB	7529	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	28735896
MIRT786616	hsa-miR-4753-3p	Homo sapiens	YWHAB	7529	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	27418678
MIRT788883	hsa-miR-6809-3p	Homo sapiens	YWHAB	7529	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	28735896
MIRT788883	hsa-miR-6809-3p	Homo sapiens	YWHAB	7529	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	27418678

Gene Ontology

ID	GO ID	GO Term	GO Type
7529	GO:0051291	protein heterooligomerization	GOTERM_BP_DIRECT
7529	GO:0019899	enzyme binding	GOTERM_MF_DIRECT
7529	GO:0030659	cytoplasmic vesicle membrane	GOTERM_CC_DIRECT
7529	GO:0035308	negative regulation of protein dephosphorylation	GOTERM_BP_DIRECT
7529	GO:0042826	histone deacetylase binding	GOTERM_MF_DIRECT
7529	GO:0000165	MAPK cascade	GOTERM_BP_DIRECT
7529	GO:0050815	RAGE receptor binding	GOTERM_MF_DIRECT
7529	GO:0005737	cytoplasm	GOTERM_CC_DIRECT
7529	GO:0016020	membrane	GOTERM_CC_DIRECT
7529	GO:0043488	regulation of mRNA stability	GOTERM_BP_DIRECT
7529	GO:0098641	cadherin binding involved in cell-cell adhesion	GOTERM_MF_DIRECT
7529	GO:0048471	perinuclear region of cytoplasm	GOTERM_CC_DIRECT
7529	GO:0008022	protein C-terminus binding	GOTERM_MF_DIRECT
7529	GO:0005925	focal adhesion	GOTERM_CC_DIRECT
7529	GO:0070062	extracellular exosome	GOTERM_CC_DIRECT
7529	GO:0035329	hippo signaling	GOTERM_BP_DIRECT
7529	GO:0061024	membrane organization	GOTERM_BP_DIRECT
7529	GO:0005829	cytosol	GOTERM_CC_DIRECT
7529	GO:0042470	melanosome	GOTERM_CC_DIRECT
7529	GO:0043085	positive regulation of catalytic activity	GOTERM_BP_DIRECT
7529	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway	GOTERM_BP_DIRECT
7529	GO:0045892	negative regulation of transcription	GOTERM_BP_DIRECT
7529	GO:0098609	cell-cell adhesion	GOTERM_BP_DIRECT
7529	GO:0032403	protein complex binding	GOTERM_MF_DIRECT
7529	GO:0005634	nucleus	GOTERM_CC_DIRECT
7529	GO:0019904	protein domain specific binding	GOTERM_MF_DIRECT
7529	GO:0005515	protein binding	GOTERM_MF_DIRECT
7529	GO:0006605	protein targeting	GOTERM_BP_DIRECT
7529	GO:0051219	vitamin transporter activity	GOTERM_MF_DIRECT
7529	GO:0005913	cell-cell adherens junction	GOTERM_CC_DIRECT
7529	GO:0043234	protein complex	GOTERM_CC_DIRECT
7529	GO:0016032	viral process	GOTERM_BP_DIRECT
7529	GO:1900740	positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	GOTERM_BP_DIRECT
7529	GO:0003714	transcription corepressor activity	GOTERM_MF_DIRECT
7529	GO:0017053	transcriptional repressor complex	GOTERM_CC_DIRECT
7529	GO:0051220	cytoplasmic sequestering of protein	GOTERM_BP_DIRECT
7529	GO:0005739	mitochondrion	GOTERM_CC_DIRECT

Pathways

Human Entrez ID	KEGG ID	KEGG Term
7529	hsa04114	Oocyte meiosis
7529	hsa04110	Cell cycle
7529	hsa04151	PI3K-Akt signaling pathway
7529	hsa04390	Hippo signaling pathway
7529	hsa05161	Hepatitis B
7529	hsa05203	Viral carcinogenesis

Association with Disease

Protein Official Symbol	Human Entrez ID	Disease Name	Disease Id	Disease Semantic Type	Semantic score	DSI	DPI	Disease Type

Association with Drug

Protein Official Symbol	Human Entrez ID	drug_claim_primary_name	drug_name	drug_chembl_id	interaction_types