ALTITUDEOMICSDB

A-Raf proto-oncogene, serine/threonine kinase

AltitudeomicsDB

Protein Official symbol	ARAF
Aliases	ARAF ARAF1 PKS PKS2
Chromosomal Location	X
Length	606
Uniprot ID	P10398
EC number	2.7.11.1
Protein family Information(Pfam)	PF00130;PF07714;PF02196;
PDB id	1WXM;2MSE;
InterPro ID	IPR020454;IPR011009;IPR002219;IPR000719;IPR017441;IPR003116;IPR001245;IPR008271;IPR029071;
dbSNP	rs56197559 rs55852926

Protein Protein Interaction

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AltitudeomicsDB

Protein 1	Protein 2	Combine Score
PPP2CA	PPP2R1A	0.9990000000000001
PPP2R1A	PPP2CB	0.9990000000000001
HRAS	RAF1	0.9990000000000001
PPP2CA	PPP2R5C	0.9990000000000001
MAP2K1	BRAF	0.9990000000000001
PPP2R5C	PPP2R1A	0.9990000000000001
PPP2R5D	PPP2R1A	0.998
KSR2	MAP2K1	0.998
PPP2R5E	PPP2R1A	0.998
PPP2CA	PPP2R5A	0.998
PPP2R1A	PPP2R5A	0.998
PPP2CA	PPP2R5B	0.998
PPP2CA	PPP2R5D	0.998
RAP1A	RAF1	0.998
PPP2CA	PPP2R5E	0.998
PPP2R1A	PPP2R5B	0.997
HRAS	BRAF	0.997
BRAF	KRAS	0.997
PPP2R5D	PPP2CB	0.997
PPP2R5E	PPP2CB	0.997
NRAS	RAF1	0.996
NRAS	KRAS	0.996
KRAS	RAF1	0.995
NRAS	BRAF	0.995
HRAS	KRAS	0.995
HRAS	NRAS	0.995
KSR1	MAP2K1	0.995
HRAS	ARAF	0.9940000000000001
HRAS	MAP2K1	0.9940000000000001
SRC	FN1	0.9940000000000001
KSR1	MAP2K2	0.9940000000000001
NRAS	ARAF	0.9940000000000001
KSR1	CNKSR2	0.9940000000000001
BRAF	MAP2K2	0.9940000000000001
PPP2R5C	PPP2CB	0.993
ARAF	MAP2K2	0.992
PPP2R5D	PPP2R5A	0.991
HRAS	SRC	0.991
MAP2K2	MAPK1	0.991
ARAF	KRAS	0.991
MAP2K1	MAPK1	0.991
MAP2K1	MAPK3	0.991
MAPK3	MAP2K2	0.991
PPP2R5A	PPP2CB	0.99
PPP2R5C	PPP2R5E	0.99
PPP2CA	PPP2CB	0.99
KSR1	CNKSR1	0.9890000000000001
MAP2K1	RAF1	0.9890000000000001
KSR2	MAP2K2	0.9890000000000001
MAP2K2	RAF1	0.988
ARRB2	MAPK3	0.988
MAP2K1	ARAF	0.988
PEBP1	RAF1	0.988
YWHAB	RAF1	0.988
MAPK3	MAPK1	0.987
NRAS	MAP2K1	0.986
HRAS	MAP2K2	0.986
MAP2K1	KRAS	0.986
RAF1	RAP1B	0.986
CNKSR2	RAF1	0.986
BCL2L11	MAPK3	0.985
KRAS	MAPK1	0.985
RAP1A	BRAF	0.985
HRAS	MAPK3	0.985
HRAS	MAPK1	0.9840000000000001
PPP2CB	PPP2R5B	0.983
MAPK3	KRAS	0.983
ARRB1	MAPK1	0.982
BCL2L11	MAPK1	0.982
MAP2K1	MAP2K2	0.982
RAF1	RRAS	0.982
KSR1	MAPK1	0.981
HRAS	JAK2	0.981
KSR2	CNKSR2	0.981
BRAF	RAP1B	0.98
MAP2K2	KRAS	0.98
ARRB1	MAPK3	0.98
YWHAB	BRAF	0.98
NRAS	MAP2K2	0.98
NRAS	MAPK3	0.9790000000000001
RAP1A	ARAF	0.9790000000000001
IQGAP1	MAPK1	0.9790000000000001
CNKSR1	RAF1	0.978
IQGAP1	MAPK3	0.977
NRAS	MAPK1	0.977
ARAF	RAP1B	0.977
SRC	IQGAP1	0.977
SRC	KRAS	0.975
FN1	ITGA2B	0.9740000000000001
ARRB1	SRC	0.9740000000000001
YWHAB	ARAF	0.973
ARRB2	MAPK1	0.972
KSR2	MAPK3	0.971
FN1	MAPK3	0.97
KSR1	MAPK3	0.97
KSR1	RAF1	0.97
KIAA1549	BRAF	0.9690000000000001
BRAF	MAPK3	0.9690000000000001
BRAP	KSR1	0.9690000000000001
ARRB1	ARRB2	0.968
KSR1	BRAF	0.9670000000000001
PPP2CA	MAPK3	0.9670000000000001
MARK3	KSR1	0.966
ARRB2	SRC	0.966
HRAS	IQGAP1	0.966
KSR2	MAPK1	0.965
HRAS	KSR1	0.965
MAPK3	RAF1	0.965
FN1	MAPK1	0.965
RAP1A	IQGAP1	0.965
RRAS2	RAF1	0.965
KSR2	BRAF	0.965
PHB	RAF1	0.965
RAF1	MAPK1	0.9640000000000001
BRAF	MAPK1	0.9640000000000001
SRC	MAPK3	0.9640000000000001
PPP2CA	MAPK1	0.963
SRC	MAPK1	0.963
MAP2K1	PEBP1	0.963
JAK2	RAF1	0.9620000000000001
JAK2	KRAS	0.9620000000000001
LAMTOR3	BRAF	0.9620000000000001
KSR2	RAF1	0.961
LAMTOR3	ARAF	0.961
JAK2	NRAS	0.961
LAMTOR3	MAP2K1	0.96
KSR1	KRAS	0.96
BRAF	IQGAP1	0.96
LAMTOR3	MAPK1	0.96
JAK2	FN1	0.96
JAK2	SRC	0.9590000000000001
LAMTOR3	MAPK3	0.9590000000000001
PPP2CA	RAF1	0.9590000000000001
IQGAP1	MAP2K2	0.9590000000000001
HRAS	PEBP1	0.958
LAMTOR3	WDR83	0.958
KSR1	NRAS	0.958
MARK3	YWHAB	0.958
HRAS	FN1	0.958
SRC	RAF1	0.958
HRAS	KSR2	0.9570000000000001
PAQR3	RAF1	0.9570000000000001
FN1	CSK	0.9570000000000001
PEBP1	MAPK1	0.956
SRC	CSK	0.956
SRC	NRAS	0.955
HRAS	CNKSR2	0.955
KSR2	KRAS	0.9540000000000001
BCL2L11	MAP2K1	0.9540000000000001
HRAS	BCL2L11	0.9540000000000001
CNKSR1	BRAF	0.9540000000000001
ARRB2	MAP2K1	0.9540000000000001
FN1	KRAS	0.953
SRC	RRAS	0.953
SRC	MAP2K1	0.953
PEBP1	KRAS	0.953
BRAF	RAF1	0.9520000000000001
KSR2	NRAS	0.9520000000000001
ARAF	BRAF	0.9520000000000001
LAMTOR3	MAP2K2	0.951
ARRB2	RAF1	0.95
PPP2R1A	KRAS	0.95
PPP2CA	YWHAB	0.95
PPP2CA	MAP2K1	0.95
BCL2L11	SRC	0.95
BCL2L11	KRAS	0.95
FN1	MAP2K1	0.95
ARRB1	CSK	0.95
CNKSR2	ARAF	0.9490000000000001
BRAP	RAF1	0.9490000000000001
KSR1	ARAF	0.9490000000000001
PHB	KRAS	0.9490000000000001
HRAS	PPP2R1A	0.9490000000000001
ARAF	MAPK1	0.9490000000000001
YWHAB	PEBP1	0.9490000000000001
HRAS	BRAP	0.948
CNKSR1	MAP2K2	0.948
ARAF	RRAS2	0.948
CNKSR2	BRAF	0.948
HRAS	RAP1B	0.948
FN1	RAF1	0.9470000000000001
RRAS	MAPK1	0.9470000000000001
IQGAP1	RAP1B	0.9470000000000001
AKAP9	BRAF	0.9470000000000001
PPP2R5C	RAF1	0.9470000000000001
MAP2K1	IQGAP1	0.9470000000000001
KSR2	ARAF	0.946
YWHAB	MAP2K1	0.946
BCL2L11	RAF1	0.946
KSR1	IQGAP1	0.946
ARAF	MAPK3	0.946
YWHAB	MAP2K2	0.945
RAP1A	MAPK3	0.945
SRC	MAP2K2	0.9440000000000001
KSR1	PPP2R5E	0.9440000000000001
KSR1	PPP2R5B	0.9440000000000001
LAMTOR3	RAF1	0.9440000000000001
CNKSR1	ARAF	0.9440000000000001
ARRB1	MAP2K1	0.9440000000000001
MAPK3	PEBP1	0.943
SRC	RAP1A	0.943
WDR83	MAP2K2	0.9420000000000001
KSR1	PPP2R5A	0.9420000000000001
RAP1A	MAPK1	0.9420000000000001
IQGAP1	KRAS	0.9420000000000001
CNKSR2	KRAS	0.9420000000000001
KSR1	PPP2CB	0.9420000000000001
HRAS	YWHAB	0.9420000000000001
HRAS	CSK	0.941
MAPK3	RAP1B	0.941
KSR2	YWHAB	0.941
KSR1	YWHAB	0.941
ARRB2	MAP2K2	0.941
BCL2L11	NRAS	0.94
ATG7	MAPK3	0.94
BRAF	RRAS	0.94
JAK2	MAP2K1	0.94
PHB	YWHAB	0.94
KSR1	PEBP1	0.94
HRAS	ATG7	0.94
YWHAB	PPP2R1A	0.94
CNKSR2	NRAS	0.94
SRC	RAP1B	0.9390000000000001
MAPK3	CSK	0.9390000000000001
MAP2K1	CSK	0.9390000000000001
ITGA2B	RAP1B	0.9390000000000001
PPP2CA	ARRB2	0.9390000000000001
BCL2L11	YWHAB	0.9390000000000001
BCL2L11	BRAF	0.9390000000000001
ATG7	KRAS	0.9390000000000001
YWHAB	RAP1A	0.938
ARAF	PEBP1	0.938
BRAP	BRAF	0.938
ARAF	RAF1	0.938
PPP2R1A	RAF1	0.938
WDR83	MAP2K1	0.938
TRIM24	BRAF	0.938
WDR83	RAF1	0.938
ARRB1	RAF1	0.938
RAP1A	MAP2K1	0.938
WDR83	MAPK1	0.938
PHB	HRAS	0.938
YWHAB	PPP2CB	0.938
JAK2	MAPK3	0.937
BRAF	PPP2CB	0.937
AKAP9	TRIM24	0.937
ARRB2	AP3B1	0.937
MAP2K2	CSK	0.937
KIAA1549	HRAS	0.937
ARRB1	AP3B1	0.937
BCL2L11	ATG7	0.937
RAP1B	MAPK1	0.937
KIAA1549	RAF1	0.937
PPP2R5C	MAPK1	0.937
IQGAP1	RAF1	0.937
MAPK1	PPP5C	0.937
PPP2R5C	PPP2R5A	0.9359999999999999
ATG7	MAPK1	0.9359999999999999
BCL2L11	JAK2	0.9359999999999999
KRAS	CSK	0.9359999999999999
ARRB2	CSK	0.9359999999999999
CSK	MAPK1	0.9359999999999999
MAPK1	PPP2R5B	0.935
YWHAB	PPP5C	0.935
SRC	ITGA2B	0.935
KSR1	RAP1B	0.934
SRC	YWHAB	0.934
JAK2	MAPK1	0.934
WDR83	MAPK3	0.934
KIAA1549	ARAF	0.934
FN1	IQGAP1	0.934
BCL2L11	FN1	0.9329999999999999
YWHAB	NRAS	0.9329999999999999
RAP1A	MAP2K2	0.9329999999999999
KSR2	CNKSR1	0.9329999999999999
KIAA1549	KRAS	0.9329999999999999
YWHAB	KRAS	0.9329999999999999
KIAA1549	AKAP9	0.932
KRAS	AP3B1	0.932
MAP2K2	PEBP1	0.932
NRAS	IQGAP1	0.932
KRAS	PPP2CB	0.932
FN1	BRAF	0.932
MAP2K1	RAP1B	0.932
YWHAB	MAPK3	0.932
PPP2CA	HRAS	0.932
CNKSR1	SRC	0.9309999999999999
FN1	RAP1B	0.9309999999999999
PPP2R1A	MAPK3	0.9309999999999999
MAP2K2	RAP1B	0.9309999999999999
RAF1	PPP2CB	0.9309999999999999
JAK2	MAP2K2	0.9309999999999999
KSR1	FN1	0.93
PPP2CA	KRAS	0.93
PPP2CA	MAP2K2	0.93
JAK2	BRAF	0.93
KDM7A	BRAF	0.93
NRAS	CSK	0.929
YWHAB	MAPK1	0.929
AKAP9	RAF1	0.929
PPP2CA	ARRB1	0.929
HRAS	AP3B1	0.929
KSR1	RAP1A	0.929
JAK2	ARAF	0.9279999999999999
FN1	ARAF	0.9279999999999999
NRAS	FN1	0.9279999999999999
KSR2	RAP1B	0.927
ARAF	RRAS	0.927
KSR2	RAP1A	0.927
PPP2CA	NRAS	0.927
RAP1A	FN1	0.927
AKAP9	ARAF	0.927
YWHAB	RAP1B	0.927
MARK3	BRAP	0.927
PPP2CA	ARAF	0.927
TRIM24	RAF1	0.927
PPP2CA	BRAF	0.9259999999999999
ARRB2	PEBP1	0.9259999999999999
ARAF	PPP2CB	0.9259999999999999
SRC	BRAF	0.9259999999999999
BRAF	RRAS2	0.9259999999999999
PPP2CA	KSR1	0.9259999999999999
HRAS	CNKSR1	0.9259999999999999
HRAS	PPP2CB	0.9259999999999999
PPP2R1A	MAPK1	0.9259999999999999
SRC	ARAF	0.9259999999999999
KIAA1549	TRIM24	0.925
MAPK3	PPP2CB	0.925
PPP2R5E	KRAS	0.925
PHB	BRAF	0.925
BRAF	PEBP1	0.925
SRC	PEBP1	0.925
MAPK3	ITGA2B	0.925
BCL2L11	MAP2K2	0.925
PPP2CB	MAPK1	0.924
KSR2	FN1	0.924
YWHAB	IQGAP1	0.924
SRC	ATG7	0.924
BCL2L11	ARAF	0.924
ARRB1	KRAS	0.924
KIAA1549	MAP2K1	0.9229999999999999
NRAS	PPP2CB	0.9229999999999999
MAPK3	PPP5C	0.9229999999999999
TRIM24	ARAF	0.9229999999999999
BCL2L11	TRIM24	0.9229999999999999
YWHAB	ITGA2B	0.9229999999999999
CNKSR1	KRAS	0.9229999999999999
AKAP9	MAP2K2	0.922
HRAS	TRIM24	0.922
HRAS	AKAP9	0.922
ARRB1	FN1	0.9209999999999999
HRAS	ARRB2	0.9209999999999999
CNKSR2	MAP2K1	0.9209999999999999
KIAA1549	AGTRAP	0.9209999999999999
ARRB2	KRAS	0.9209999999999999
JAK2	RAP1A	0.9209999999999999
PPP2R5D	ARAF	0.9209999999999999
FN1	PEBP1	0.9209999999999999
PPP2R5C	HRAS	0.9209999999999999
HRAS	RAP1A	0.9209999999999999
RAP1A	NRAS	0.9209999999999999
CNKSR2	MAP2K2	0.9209999999999999
ARRB2	BRAF	0.9209999999999999
KSR1	AKAP9	0.9209999999999999
NRAS	RAP1B	0.92
KRAS	RAP1B	0.92
KSR1	SRC	0.92
FN1	MAP2K2	0.92
RAP1A	KRAS	0.92
ARRB1	YWHAB	0.92
RAF1	PPP5C	0.92
MARK3	HRAS	0.919
ARRB1	AKAP9	0.919
JAK2	YWHAB	0.919
PPP2R5E	ARAF	0.919
RAP1A	CSK	0.919
PPP2R5D	RAF1	0.919
AKAP9	MAP2K1	0.919
ARAF	PPP5C	0.919
ARRB1	HRAS	0.919
KIAA1549	MAP2K2	0.919
ARAF	IQGAP1	0.919
ARRB2	AKAP9	0.919
TRIM24	MAP2K1	0.9179999999999999
PPP2R1A	MAP2K2	0.9179999999999999
KDM7A	TRIM24	0.9179999999999999
HRAS	ITGA2B	0.9179999999999999
CNKSR2	CNKSR1	0.9179999999999999
PHB	NRAS	0.917
KIAA1549	NRAS	0.917
PPP2R5E	RAF1	0.917
ARRB1	MAP2K2	0.917
ARRB1	KSR1	0.917
PPP2R1A	MAP2K1	0.917
MARK3	RAF1	0.917
YWHAB	CSK	0.917
ARRB1	BRAF	0.917
RAP1A	AP3B1	0.917
PPP2R5E	BRAF	0.917
HRAS	PPP5C	0.917
CNKSR1	NRAS	0.917
JAK2	ATG7	0.917
NRAS	AP3B1	0.917
AP3B1	RAP1B	0.917
NRAS	PEBP1	0.917
RAP1B	CSK	0.917
ITGA2B	MAPK1	0.9159999999999999
PPP2R5D	KSR1	0.9159999999999999
ARRB2	YWHAB	0.9159999999999999
RAP1A	RAP1B	0.9159999999999999
PPP2R5C	KSR1	0.9159999999999999
ARAF	PPP2R5A	0.9159999999999999
KSR1	BCL2L11	0.915
ARRB1	IQGAP1	0.915
MAP2K1	ITGA2B	0.915
NRAS	PPP5C	0.915
CNKSR2	MAPK1	0.915
HRAS	PPP2R5E	0.915
PPP2R5A	RAF1	0.915
PPP2R5C	BRAF	0.915
RAF1	PPP2R5B	0.915
PPP2R5C	KRAS	0.915
KRAS	PPP5C	0.915
ARRB2	FN1	0.915
ATG7	MAP2K1	0.915
PPP2R5D	BRAF	0.915
MARK3	ITGA2B	0.915
ARAF	PPP2R5B	0.915
PPP2R5D	YWHAB	0.915
BRAF	PPP2R5B	0.915
TRIM24	MAP2K2	0.915
BRAF	PPP2R5A	0.915
RAP1A	ITGA2B	0.915
ARRB2	ARAF	0.915
PPP2R5C	ARAF	0.915
ARRB1	ARAF	0.915
YWHAB	PPP2R5E	0.914
CNKSR1	TRIM24	0.914
AGTRAP	MAPK3	0.914
CNKSR2	SRC	0.914
KSR1	AP3B1	0.914
CNKSR1	IQGAP1	0.914
FN1	ATG7	0.9129999999999999
BRAF	PPP5C	0.9129999999999999
KDM7A	ARAF	0.9129999999999999
CNKSR1	MAPK3	0.9129999999999999
CNKSR2	MAPK3	0.9129999999999999
KSR2	KDM7A	0.9129999999999999
KDM7A	RAF1	0.9129999999999999
CNKSR2	YWHAB	0.9129999999999999
KSR1	KDM7A	0.9129999999999999
AKAP9	AGTRAP	0.9129999999999999
ARRB2	KSR1	0.9129999999999999
NRAS	ATG7	0.9129999999999999
ARRB1	KSR2	0.912
CNKSR1	RAP1B	0.912
SRC	AKAP9	0.912
CNKSR2	RAP1A	0.912
CNKSR1	PEBP1	0.912
CNKSR1	RAP1A	0.912
YWHAB	FN1	0.912
KSR1	PPP5C	0.912
TRIM24	KRAS	0.912
JAK2	TRIM24	0.912
ATG7	RAF1	0.912
CNKSR2	RAP1B	0.912
MARK3	CNKSR1	0.912
PPP2R5A	KRAS	0.912
IQGAP1	CSK	0.912
CNKSR1	MAP2K1	0.912
YWHAB	AP3B1	0.9109999999999999
ARAF	CSK	0.9109999999999999
CNKSR1	MAPK1	0.9109999999999999
MARK3	ARAF	0.9109999999999999
RAF1	CSK	0.9109999999999999
BRAP	KRAS	0.9109999999999999
AGTRAP	BRAF	0.9109999999999999
BRAP	ARAF	0.9109999999999999
HRAS	PPP2R5B	0.9109999999999999
ARRB2	AGTRAP	0.9109999999999999
BRAP	NRAS	0.9109999999999999
LAMTOR3	NRAS	0.9109999999999999
PPP2R5D	HRAS	0.91
CNKSR1	CSK	0.91
KSR2	PEBP1	0.91
PPP2R1A	ARAF	0.91
AKAP9	KRAS	0.91
MARK3	PPP2CB	0.91
TRIM24	MAPK1	0.91
LAMTOR3	RAP1A	0.91
ARRB2	KSR2	0.91
CNKSR2	CSK	0.91
AGTRAP	ARAF	0.91
PAQR3	ARAF	0.91
NRAS	TRIM24	0.909
SRC	TRIM24	0.909
ITGA2B	CSK	0.909
KSR2	SRC	0.909
KSR1	JAK2	0.909
PPP2R1A	BRAF	0.909
MARK3	SRC	0.909
MARK3	KSR2	0.909
ARRB2	RAP1A	0.909
AGTRAP	RAF1	0.909
PHB	ARAF	0.909
PPP2R5C	MAPK3	0.909
KDM7A	ATG7	0.909
HRAS	PPP2R5A	0.909
TRIM24	MAPK3	0.9079999999999999
PPP2R5D	MAPK3	0.9079999999999999
ARAF	ITGA2B	0.9079999999999999
MARK3	BRAF	0.9079999999999999
NRAS	PPP2R5E	0.9079999999999999
ATG7	MAP2K2	0.9079999999999999
MARK3	MAPK3	0.9079999999999999
PPP2R5D	NRAS	0.9079999999999999
WDR83	ARAF	0.9079999999999999
PPP2R5D	KRAS	0.9079999999999999
KIAA1549	MAPK3	0.9079999999999999
IQGAP1	PEBP1	0.9079999999999999
KRAS	PPP2R5B	0.9079999999999999
KSR2	AKAP9	0.9079999999999999
MARK3	MAP2K1	0.9079999999999999
NRAS	PPP2R5B	0.9079999999999999
NRAS	PPP2R5A	0.9079999999999999
AKAP9	RAP1B	0.9079999999999999
PPP2R5C	NRAS	0.9079999999999999
AKAP9	IQGAP1	0.9079999999999999
AGTRAP	MAPK1	0.907
PPP2R5C	YWHAB	0.907
MAPK3	PPP2R5B	0.907
KIAA1549	KDM7A	0.907
BRAF	CSK	0.907
ARRB2	IQGAP1	0.907
AKAP9	FN1	0.907
ARRB1	RAP1A	0.907
MARK3	FN1	0.907
PPP2R5D	MARK3	0.907
MAP2K2	ITGA2B	0.907
KDM7A	SRC	0.907
KDM7A	JAK2	0.907
SRC	AP3B1	0.907
YWHAB	ATG7	0.907
BCL2L11	CSK	0.907
AP3B1	RAF1	0.9059999999999999
YWHAB	PPP2R5B	0.9059999999999999
NRAS	AKAP9	0.9059999999999999
MARK3	PPP2R5E	0.9059999999999999
KSR1	ATG7	0.9059999999999999
PPP2R5C	MARK3	0.9059999999999999
KSR1	CSK	0.9059999999999999
ATG7	ARAF	0.9059999999999999
PHB	KSR1	0.9059999999999999
MARK3	CSK	0.9059999999999999
NRAS	ITGA2B	0.9059999999999999
RAP1A	AKAP9	0.9059999999999999
MAPK3	AP3B1	0.9059999999999999
KSR2	ATG7	0.9059999999999999
BCL2L11	PEBP1	0.9059999999999999
KIAA1549	MAPK1	0.9059999999999999
ATG7	BRAF	0.9059999999999999
ARAF	AP3B1	0.9059999999999999
BRAF	AP3B1	0.9059999999999999
MARK3	MAPK1	0.9059999999999999
KSR2	BCL2L11	0.9059999999999999
YWHAB	PPP2R5A	0.9059999999999999
BCL2L11	ITGA2B	0.9059999999999999
KSR2	AP3B1	0.9059999999999999
KSR2	TRIM24	0.9059999999999999
AKAP9	PEBP1	0.905
KIAA1549	YWHAB	0.905
PPP2R5D	PPP2R5B	0.905
KSR1	TRIM24	0.905
ARRB1	BCL2L11	0.905
KIAA1549	KSR1	0.905
ITGA2B	RAF1	0.905
MARK3	MAP2K2	0.905
KDM7A	CSK	0.905
PPP2R5D	MAPK1	0.905
AP3B1	MAPK1	0.905
AKAP9	MAPK1	0.905
ATG7	AP3B1	0.905
ITGA2B	KRAS	0.905
MARK3	IQGAP1	0.905
ARRB2	ITGA2B	0.904
KSR1	PPP2R1A	0.904
ARRB2	NRAS	0.904
ATG7	RAP1B	0.904
MARK3	JAK2	0.904
MARK3	TRIM24	0.904
KSR2	KSR1	0.904
ATG7	CSK	0.904
AP3B1	CSK	0.904
HRAS	KDM7A	0.904
KDM7A	KRAS	0.904
BRAF	ITGA2B	0.904
KSR2	ITGA2B	0.904
FN1	AP3B1	0.904
KDM7A	NRAS	0.904
RAP1A	ATG7	0.904
KSR1	ITGA2B	0.904
PPP2R5D	PPP2R5E	0.904
KDM7A	AP3B1	0.904
CNKSR2	IQGAP1	0.904
CNKSR1	YWHAB	0.904
ARRB1	NRAS	0.904
JAK2	AP3B1	0.904
KSR2	CSK	0.904
AKAP9	MAPK3	0.904
MARK3	RAP1B	0.903
YWHAB	AKAP9	0.903
MARK3	RAP1A	0.903
NRAS	PPP2R1A	0.903
TRIM24	CSK	0.903
MARK3	AKAP9	0.903
PPP2R5C	PPP2R5B	0.903
FN1	TRIM24	0.903
ARRB1	PEBP1	0.903
PPP2R5D	PPP2R5C	0.903
KIAA1549	SRC	0.903
PPP2R5E	PPP2R5A	0.903
PAQR3	BRAF	0.903
PEBP1	RAP1B	0.903
LAMTOR3	YWHAB	0.903
PPP2R5D	AKAP9	0.903
ARRB1	AGTRAP	0.903
AKAP9	CSK	0.903
MARK3	PPP2R5B	0.903
MARK3	KDM7A	0.903
MARK3	PPP2R5A	0.903
FN1	AGTRAP	0.903
AKAP9	ITGA2B	0.903
KIAA1549	CNKSR1	0.902
ARRB1	PPP2R1A	0.902
KDM7A	RAP1A	0.902
CNKSR2	FN1	0.902
CNKSR2	AP3B1	0.902
PEBP1	CSK	0.902
PPP2R5E	PPP2R5B	0.902
RAP1A	TRIM24	0.902
PPP2CA	MARK3	0.902
MAP2K1	AP3B1	0.902
RAP1A	PEBP1	0.902
CNKSR1	FN1	0.902
KDM7A	MAPK3	0.902
KDM7A	MAPK1	0.902
IQGAP1	ITGA2B	0.902
MARK3	CNKSR2	0.902
BRAP	YWHAB	0.902
IQGAP1	AP3B1	0.902
ARRB1	ITGA2B	0.902
MARK3	ARRB2	0.902
KDM7A	IQGAP1	0.902
CNKSR2	PEBP1	0.902
KDM7A	RAP1B	0.902
YWHAB	AGTRAP	0.902
MAP2K2	AP3B1	0.902
KIAA1549	CNKSR2	0.902
AGTRAP	KRAS	0.902
KDM7A	AKAP9	0.902
ARRB2	ATG7	0.902
TRIM24	RAP1B	0.902
ATG7	ITGA2B	0.9009999999999999
JAK2	AGTRAP	0.9009999999999999
MARK3	KRAS	0.9009999999999999
WDR83	BRAF	0.9009999999999999
HRAS	AGTRAP	0.9009999999999999
PPP2R5A	PPP2R5B	0.9009999999999999
ITGA2B	PEBP1	0.9009999999999999
MARK3	AP3B1	0.9009999999999999
MARK3	PEBP1	0.9009999999999999
ARRB1	CNKSR2	0.9009999999999999
KSR2	IQGAP1	0.9009999999999999
JAK2	AKAP9	0.9009999999999999
CNKSR1	AP3B1	0.9009999999999999
KIAA1549	IQGAP1	0.9009999999999999
PEBP1	AP3B1	0.9009999999999999
YWHAB	TRIM24	0.9009999999999999
ITGA2B	AP3B1	0.9009999999999999
CNKSR2	TRIM24	0.9009999999999999
ARRB1	ATG7	0.9009999999999999
AGTRAP	IQGAP1	0.9
SRC	AGTRAP	0.9
KIAA1549	ITGA2B	0.9
ATG7	IQGAP1	0.9
KDM7A	CNKSR1	0.9
CNKSR2	ITGA2B	0.9
KDM7A	BCL2L11	0.9
NRAS	AGTRAP	0.9
KDM7A	MAP2K1	0.9
KDM7A	MAP2K2	0.9
AGTRAP	MAP2K1	0.9
ATG7	PEBP1	0.9
KDM7A	CNKSR2	0.9
TRIM24	ITGA2B	0.9
ARRB2	CNKSR1	0.9
AGTRAP	ITGA2B	0.9
KIAA1549	AP3B1	0.9
BCL2L11	CNKSR2	0.9
CNKSR1	AGTRAP	0.9
KIAA1549	PEBP1	0.9
BCL2L11	AP3B1	0.9
KIAA1549	ARRB2	0.9
KIAA1549	RAP1A	0.9
AGTRAP	RAP1B	0.9
AKAP9	PPP2R1A	0.9
ATG7	TRIM24	0.9
AGTRAP	CSK	0.9
ARRB2	TRIM24	0.9
MARK3	PPP2R1A	0.9
ARRB2	CNKSR2	0.9
MARK3	BCL2L11	0.9
TRIM24	AP3B1	0.9
KIAA1549	ATG7	0.9
CNKSR1	ITGA2B	0.9
AGTRAP	PEBP1	0.9
KIAA1549	KSR2	0.9
ATG7	AGTRAP	0.9
KIAA1549	RAP1B	0.9
ARRB1	TRIM24	0.9
ARRB1	KDM7A	0.9
KDM7A	ITGA2B	0.9
BCL2L11	CNKSR1	0.9
AGTRAP	MAP2K2	0.9
KIAA1549	ARRB1	0.9
ARRB2	PPP2R1A	0.9
AGTRAP	AP3B1	0.9
ARRB1	RAP1B	0.9
BCL2L11	AGTRAP	0.9
KDM7A	PEBP1	0.9
AKAP9	AP3B1	0.9
ARRB2	BCL2L11	0.9
TRIM24	IQGAP1	0.9
MARK3	ARRB1	0.9
ARRB1	CNKSR1	0.9
AKAP9	ATG7	0.9
ARRB2	KDM7A	0.9
KIAA1549	FN1	0.9
TRIM24	PEBP1	0.9
CNKSR2	AKAP9	0.9
KIAA1549	MARK3	0.9
KIAA1549	JAK2	0.9
KSR2	AGTRAP	0.9
KSR1	AGTRAP	0.9
CNKSR1	ATG7	0.9
BCL2L11	AKAP9	0.9
CNKSR2	AGTRAP	0.9
KIAA1549	CSK	0.9
KIAA1549	BCL2L11	0.9
KDM7A	FN1	0.9
TRIM24	AGTRAP	0.9
MARK3	NRAS	0.9
BCL2L11	RAP1B	0.9
BCL2L11	RAP1A	0.9
MARK3	ATG7	0.9
BCL2L11	IQGAP1	0.9
CNKSR1	AKAP9	0.9
RAP1A	AGTRAP	0.9
KDM7A	YWHAB	0.9
CNKSR2	ATG7	0.9
MARK3	AGTRAP	0.9
ARRB2	RAP1B	0.9
KDM7A	AGTRAP	0.9

Gene Ontology Semantic Similarity

Download Tab separated file

#	5515 (PPP2CA)	5518 (PPP2R1A)	3265 (HRAS)	5604 (MAP2K1)	5527 (PPP2R5C)	5528 (PPP2R5D)	283455 (KSR2)	5529 (PPP2R5E)	5906 (RAP1A)	673 (BRAF)	4893 (NRAS)	3845 (KRAS)	8844 (KSR1)	6714 (SRC)	369 (ARAF)	5605 (MAP2K2)	5595 (MAPK3)	5525 (PPP2R5A)	409 (ARRB2)	5037 (PEBP1)	7529 (YWHAB)	5894 (RAF1)	10018 (BCL2L11)	5516 (PPP2CB)	408 (ARRB1)	8826 (IQGAP1)	10256 (CNKSR1)	2335 (FN1)	8315 (BRAP)	4140 (MARK3)	22800 (RRAS2)	5245 (PHB)	3717 (JAK2)	8649 (LAMTOR3)	152559 (PAQR3)	6237 (RRAS)	10142 (AKAP9)	84292 (WDR83)	10533 (ATG7)	3674 (ITGA2B)	8805 (TRIM24)	5908 (RAP1B)	5594 (MAPK1)	1445 (CSK)	80853 (KDM7A)	8546 (AP3B1)	57085 (AGTRAP)	5526 (PPP2R5B)	5536 (PPP5C)
5515 (PPP2CA)	1.00	1.00	1.00	1.00	1.00	1.00	0.34	1.00	1.00	1.00	0.71	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.26	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.69	0.82	1.00	1.00	1.00
5518 (PPP2R1A)	1.00	1.00	0.53	0.48	0.88	0.60	0.27	1.00	0.59	0.51	0.71	0.70	0.58	0.60	0.49	0.49	0.51	0.69	0.70	0.62	0.70	0.52	0.66	0.60	0.65	0.61	0.70	0.64	0.55	0.60	1.00	0.66	0.52	0.69	0.26	0.56	0.66	1.00	0.58	0.71	0.52	0.51	0.50	0.57	0.31	0.57	1.00	1.00	0.50
3265 (HRAS)	1.00	0.53	1.00	0.43	0.49	0.50	0.21	1.00	0.49	0.45	0.71	0.57	0.54	0.60	0.42	0.42	0.44	0.56	0.63	0.56	0.64	0.47	0.54	0.50	0.51	0.52	0.57	0.64	0.48	0.48	1.00	0.63	0.47	0.53	0.26	0.93	0.56	1.00	0.50	0.58	0.48	0.95	0.45	0.55	0.30	0.47	1.00	1.00	0.65
5604 (MAP2K1)	1.00	0.48	0.43	1.00	0.45	0.41	0.60	1.00	0.43	0.81	0.71	0.47	0.78	0.77	0.84	0.94	0.81	0.46	0.54	0.47	0.54	0.83	0.45	0.41	0.50	0.57	0.47	0.55	0.51	0.80	1.00	0.55	0.73	0.46	0.26	0.42	0.50	1.00	0.45	0.48	0.64	0.40	0.82	0.78	0.31	0.38	1.00	1.00	0.44
5527 (PPP2R5C)	1.00	0.88	0.49	0.45	1.00	0.58	0.26	1.00	0.58	0.48	0.71	0.72	0.57	0.60	0.44	0.46	0.47	0.72	0.71	0.62	0.71	0.49	0.67	0.58	0.65	0.60	0.72	0.64	0.52	0.58	1.00	0.67	0.50	0.71	0.26	0.53	0.67	1.00	0.56	0.75	0.50	0.48	0.47	0.56	0.29	0.59	1.00	1.00	0.47
5528 (PPP2R5D)	1.00	0.60	0.50	0.41	0.58	1.00	0.25	1.00	0.54	0.47	0.71	0.71	0.56	0.60	0.44	0.43	0.47	0.71	0.71	0.61	0.71	0.49	0.66	1.00	0.55	0.54	0.71	0.64	0.53	0.56	1.00	0.66	0.48	0.62	0.26	0.54	0.62	1.00	0.56	0.74	0.50	0.49	0.47	0.56	0.30	0.58	1.00	1.00	0.70
283455 (KSR2)	0.34	0.27	0.21	0.60	0.26	0.25	1.00	0.34	0.26	0.55	0.24	0.26	0.68	0.40	0.63	0.54	0.59	0.26	0.25	0.24	0.25	0.57	0.25	0.25	0.24	0.23	0.26	0.23	0.31	0.62	0.34	0.24	0.46	0.28	0.34	0.22	0.27	0.34	0.25	0.27	0.37	0.20	0.58	0.50	0.23	0.22	0.34	0.34	0.36
5529 (PPP2R5E)	1.00	1.00	1.00	1.00	1.00	1.00	0.34	1.00	1.00	1.00	0.71	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.26	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.69	0.82	1.00	1.00	1.00
5906 (RAP1A)	1.00	0.59	0.49	0.43	0.58	0.54	0.26	1.00	1.00	0.47	1.00	0.73	0.55	0.60	0.45	0.44	0.47	0.63	0.67	0.58	0.67	0.49	0.64	0.54	0.57	0.55	0.64	0.66	0.51	0.54	1.00	0.63	0.56	0.72	0.26	0.59	0.72	1.00	0.54	0.65	0.51	0.54	0.47	0.54	0.30	0.52	1.00	1.00	0.47
673 (BRAF)	1.00	0.51	0.45	0.81	0.48	0.47	0.55	1.00	0.47	1.00	0.71	0.53	0.74	0.76	0.93	0.78	0.81	0.56	0.60	0.57	0.60	0.93	0.51	0.47	0.50	0.60	0.53	0.60	0.57	0.81	1.00	0.58	0.74	0.51	0.26	0.47	0.54	1.00	0.51	0.59	0.67	0.44	0.84	0.81	0.38	0.44	1.00	1.00	0.48
4893 (NRAS)	0.71	0.71	0.71	0.71	0.71	0.71	0.24	0.71	1.00	0.71	1.00	1.00	0.71	0.72	0.71	0.71	0.71	0.71	0.71	0.71	0.71	0.71	0.74	0.71	0.71	0.71	0.71	0.87	0.71	0.71	0.71	0.71	0.71	0.71	0.19	1.00	0.71	0.71	0.71	0.71	0.71	1.00	0.71	0.71	0.49	0.58	0.71	0.71	0.71
3845 (KRAS)	1.00	0.70	0.57	0.47	0.72	0.71	0.26	1.00	0.73	0.53	1.00	1.00	0.63	0.63	0.52	0.49	0.55	0.85	0.77	0.69	0.77	0.55	0.87	0.71	0.61	0.58	0.86	0.73	0.60	0.71	1.00	0.72	0.52	0.74	0.26	0.72	0.69	1.00	0.64	0.88	0.56	0.64	0.53	0.61	0.32	0.70	1.00	1.00	0.51
8844 (KSR1)	1.00	0.58	0.54	0.78	0.57	0.56	0.68	1.00	0.55	0.74	0.71	0.63	1.00	0.76	0.77	0.72	0.75	0.66	0.68	0.60	0.67	0.78	0.61	0.56	0.55	0.55	0.64	0.65	0.58	0.77	1.00	0.67	0.71	0.62	0.34	0.53	0.63	1.00	0.56	0.65	0.62	0.49	0.76	0.79	0.34	0.53	1.00	1.00	0.59
6714 (SRC)	1.00	0.60	0.60	0.77	0.60	0.60	0.40	1.00	0.60	0.76	0.72	0.63	0.76	1.00	0.77	0.74	0.77	0.65	0.71	0.65	0.71	0.81	0.62	0.60	0.61	0.62	0.64	0.71	0.64	0.75	1.00	0.67	0.86	0.61	0.26	0.60	0.66	1.00	0.60	0.63	0.73	0.59	0.77	0.85	0.41	0.52	1.00	1.00	0.57
369 (ARAF)	1.00	0.49	0.42	0.84	0.44	0.44	0.63	1.00	0.45	0.93	0.71	0.52	0.77	0.77	1.00	0.81	0.86	0.56	0.61	0.57	0.60	0.95	0.49	0.44	0.48	0.52	0.52	0.58	0.53	0.88	1.00	0.58	0.76	0.49	0.26	0.44	0.53	1.00	0.48	0.54	0.64	0.41	0.86	0.81	0.31	0.43	1.00	1.00	0.44
5605 (MAP2K2)	1.00	0.49	0.42	0.94	0.46	0.43	0.54	1.00	0.44	0.78	0.71	0.49	0.72	0.74	0.81	1.00	0.79	0.48	0.56	0.48	0.57	0.80	0.47	0.43	0.51	0.59	0.49	0.54	0.50	0.78	1.00	0.54	0.69	0.48	0.26	0.43	0.51	1.00	0.46	0.50	0.62	0.41	0.80	0.72	0.30	0.40	1.00	1.00	0.45
5595 (MAPK3)	1.00	0.51	0.44	0.81	0.47	0.47	0.59	1.00	0.47	0.81	0.71	0.55	0.75	0.77	0.86	0.79	1.00	0.55	0.63	0.54	0.63	0.89	0.52	0.47	0.50	0.53	0.55	0.59	0.57	0.87	1.00	0.60	0.70	0.51	0.26	0.47	0.55	1.00	0.51	0.56	0.64	0.43	0.98	0.81	0.35	0.53	1.00	1.00	0.46
5525 (PPP2R5A)	1.00	0.69	0.56	0.46	0.72	0.71	0.26	1.00	0.63	0.56	0.71	0.85	0.66	0.65	0.56	0.48	0.55	1.00	0.79	0.75	0.79	0.58	0.80	0.71	0.60	0.61	0.85	0.70	0.60	0.71	1.00	0.74	0.55	0.73	0.26	0.62	0.68	1.00	0.63	0.88	0.55	0.55	0.53	0.63	0.32	0.71	1.00	1.00	0.51
409 (ARRB2)	1.00	0.70	0.63	0.54	0.71	0.71	0.25	1.00	0.67	0.60	0.71	0.77	0.68	0.71	0.61	0.56	0.63	0.79	1.00	0.75	0.79	0.64	0.75	0.71	0.77	0.63	0.77	0.77	0.64	0.71	1.00	0.80	0.62	0.78	0.26	0.66	0.78	1.00	0.67	0.78	0.63	0.62	0.61	0.69	0.37	0.65	1.00	1.00	0.58
5037 (PEBP1)	1.00	0.62	0.56	0.47	0.62	0.61	0.24	1.00	0.58	0.57	0.71	0.69	0.60	0.65	0.57	0.48	0.54	0.75	0.75	1.00	0.75	0.60	0.66	0.61	0.62	0.65	0.69	0.70	0.56	0.61	1.00	0.75	0.58	0.64	0.26	0.58	0.63	1.00	0.59	0.71	0.56	0.55	0.53	0.62	0.33	0.60	1.00	1.00	0.52
7529 (YWHAB)	1.00	0.70	0.64	0.54	0.71	0.71	0.25	1.00	0.67	0.60	0.71	0.77	0.67	0.71	0.60	0.57	0.63	0.79	0.79	0.75	1.00	0.64	0.75	0.71	0.65	0.68	0.77	0.73	0.64	0.71	1.00	0.78	0.58	0.72	0.26	0.67	0.69	1.00	0.66	0.78	0.59	0.63	0.60	0.65	0.37	0.66	1.00	1.00	0.59
5894 (RAF1)	1.00	0.52	0.47	0.83	0.49	0.49	0.57	1.00	0.49	0.93	0.71	0.55	0.78	0.81	0.95	0.80	0.89	0.58	0.64	0.60	0.64	1.00	0.53	0.49	0.51	0.54	0.55	0.63	0.61	0.85	1.00	0.62	0.76	0.52	0.26	0.48	0.55	1.00	0.53	0.59	0.67	0.46	0.91	0.86	0.36	0.47	1.00	1.00	0.50
10018 (BCL2L11)	1.00	0.66	0.54	0.45	0.67	0.66	0.25	1.00	0.64	0.51	0.74	0.87	0.61	0.62	0.49	0.47	0.52	0.80	0.75	0.66	0.75	0.53	1.00	0.66	0.59	0.56	0.80	0.68	0.57	0.66	1.00	0.70	0.50	0.70	0.26	0.63	0.66	1.00	0.61	0.83	0.53	0.56	0.51	0.59	0.31	0.66	1.00	1.00	0.49
5516 (PPP2CB)	1.00	0.60	0.50	0.41	0.58	1.00	0.25	1.00	0.54	0.47	0.71	0.71	0.56	0.60	0.44	0.43	0.47	0.71	0.71	0.61	0.71	0.49	0.66	1.00	0.55	0.54	0.71	0.64	0.53	0.56	1.00	0.66	0.48	0.62	0.26	0.54	0.62	1.00	0.56	0.74	0.50	0.49	0.47	0.56	0.30	0.58	1.00	1.00	0.70
408 (ARRB1)	1.00	0.65	0.51	0.50	0.65	0.55	0.24	1.00	0.57	0.50	0.71	0.61	0.55	0.61	0.48	0.51	0.50	0.60	0.77	0.62	0.65	0.51	0.59	0.55	1.00	0.69	0.61	0.63	0.53	0.55	1.00	0.73	0.54	0.64	0.26	0.53	0.65	1.00	0.57	0.62	0.60	0.50	0.49	0.57	0.31	0.50	1.00	1.00	0.50
8826 (IQGAP1)	1.00	0.61	0.52	0.57	0.60	0.54	0.23	1.00	0.55	0.60	0.71	0.58	0.55	0.62	0.52	0.59	0.53	0.61	0.63	0.65	0.68	0.54	0.56	0.54	0.69	1.00	0.58	0.61	0.52	0.54	1.00	0.61	0.55	0.60	0.26	0.53	0.60	1.00	0.54	0.59	0.54	0.51	0.52	0.56	0.37	0.54	1.00	1.00	0.50
10256 (CNKSR1)	1.00	0.70	0.57	0.47	0.72	0.71	0.26	1.00	0.64	0.53	0.71	0.86	0.64	0.64	0.52	0.49	0.55	0.85	0.77	0.69	0.77	0.55	0.80	0.71	0.61	0.58	1.00	0.69	0.60	0.71	1.00	0.72	0.52	0.74	0.26	0.62	0.69	1.00	0.64	0.88	0.55	0.55	0.53	0.61	0.32	0.70	1.00	1.00	0.51
2335 (FN1)	1.00	0.64	0.64	0.55	0.64	0.64	0.23	1.00	0.66	0.60	0.87	0.73	0.65	0.71	0.58	0.54	0.59	0.70	0.77	0.70	0.73	0.63	0.68	0.64	0.63	0.61	0.69	1.00	0.63	0.64	1.00	0.73	0.59	0.66	0.26	0.67	0.68	1.00	0.63	0.72	0.60	0.65	0.60	0.68	0.37	0.58	1.00	1.00	0.60
8315 (BRAP)	1.00	0.55	0.48	0.51	0.52	0.53	0.31	1.00	0.51	0.57	0.71	0.60	0.58	0.64	0.53	0.50	0.57	0.60	0.64	0.56	0.64	0.61	0.57	0.53	0.53	0.52	0.60	0.63	1.00	0.58	1.00	0.61	0.53	0.56	0.26	0.51	0.58	1.00	0.56	0.67	0.65	0.47	0.60	0.65	0.36	0.49	1.00	1.00	0.50
4140 (MARK3)	1.00	0.60	0.48	0.80	0.58	0.56	0.62	1.00	0.54	0.81	0.71	0.71	0.77	0.75	0.88	0.78	0.87	0.71	0.71	0.61	0.71	0.85	0.66	0.56	0.55	0.54	0.71	0.64	0.58	1.00	1.00	0.66	0.69	0.62	0.26	0.52	0.62	1.00	0.56	0.74	0.62	0.47	0.87	0.79	0.31	0.58	1.00	1.00	0.46
22800 (RRAS2)	1.00	1.00	1.00	1.00	1.00	1.00	0.34	1.00	1.00	1.00	0.71	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.26	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.69	0.82	1.00	1.00	1.00
5245 (PHB)	1.00	0.66	0.63	0.55	0.67	0.66	0.24	1.00	0.63	0.58	0.71	0.72	0.67	0.67	0.58	0.54	0.60	0.74	0.80	0.75	0.78	0.62	0.70	0.66	0.73	0.61	0.72	0.73	0.61	0.66	1.00	1.00	0.57	0.68	0.26	0.63	0.67	1.00	0.63	0.73	0.65	0.59	0.58	0.65	0.36	0.61	1.00	1.00	0.56
3717 (JAK2)	1.00	0.52	0.47	0.73	0.50	0.48	0.46	1.00	0.56	0.74	0.71	0.52	0.71	0.86	0.76	0.69	0.70	0.55	0.62	0.58	0.58	0.76	0.50	0.48	0.54	0.55	0.52	0.59	0.53	0.69	1.00	0.57	1.00	0.57	0.26	0.48	0.64	1.00	0.50	0.53	0.69	0.47	0.71	0.81	0.35	0.42	1.00	1.00	0.47
8649 (LAMTOR3)	1.00	0.69	0.53	0.46	0.71	0.62	0.28	1.00	0.72	0.51	0.71	0.74	0.62	0.61	0.49	0.48	0.51	0.73	0.78	0.64	0.72	0.52	0.70	0.62	0.64	0.60	0.74	0.66	0.56	0.62	1.00	0.68	0.57	1.00	0.26	0.57	0.84	1.00	0.59	0.76	0.53	0.52	0.50	0.58	0.31	0.61	1.00	1.00	0.50
152559 (PAQR3)	0.26	0.26	0.26	0.26	0.26	0.26	0.34	0.26	0.26	0.26	0.19	0.26	0.34	0.26	0.26	0.26	0.26	0.26	0.26	0.26	0.26	0.26	0.26	0.26	0.26	0.26	0.26	0.26	0.26	0.26	0.26	0.26	0.26	0.26	1.00	0.26	0.26	0.26	0.26	0.26	0.26	0.26	0.26	0.26	0.21	0.21	0.26	0.26	0.34
6237 (RRAS)	1.00	0.56	0.93	0.42	0.53	0.54	0.22	1.00	0.59	0.47	1.00	0.72	0.53	0.60	0.44	0.43	0.47	0.62	0.66	0.58	0.67	0.48	0.63	0.54	0.53	0.53	0.62	0.67	0.51	0.52	1.00	0.63	0.48	0.57	0.26	1.00	0.59	1.00	0.53	0.64	0.50	0.99	0.47	0.54	0.31	0.51	1.00	1.00	0.63
10142 (AKAP9)	1.00	0.66	0.56	0.50	0.67	0.62	0.27	1.00	0.72	0.54	0.71	0.69	0.63	0.66	0.53	0.51	0.55	0.68	0.78	0.63	0.69	0.55	0.66	0.62	0.65	0.60	0.69	0.68	0.58	0.62	1.00	0.67	0.64	0.84	0.26	0.59	1.00	1.00	0.60	0.70	0.57	0.55	0.54	0.62	0.34	0.56	1.00	1.00	0.54
84292 (WDR83)	1.00	1.00	1.00	1.00	1.00	1.00	0.34	1.00	1.00	1.00	0.71	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.26	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.69	0.82	1.00	1.00	1.00
10533 (ATG7)	1.00	0.58	0.50	0.45	0.56	0.56	0.25	1.00	0.54	0.51	0.71	0.64	0.56	0.60	0.48	0.46	0.51	0.63	0.67	0.59	0.66	0.53	0.61	0.56	0.57	0.54	0.64	0.63	0.56	0.56	1.00	0.63	0.50	0.59	0.26	0.53	0.60	1.00	1.00	0.67	0.52	0.49	0.52	0.58	0.35	0.52	1.00	1.00	0.50
3674 (ITGA2B)	1.00	0.71	0.58	0.48	0.75	0.74	0.27	1.00	0.65	0.59	0.71	0.88	0.65	0.63	0.54	0.50	0.56	0.88	0.78	0.71	0.78	0.59	0.83	0.74	0.62	0.59	0.88	0.72	0.67	0.74	1.00	0.73	0.53	0.76	0.26	0.64	0.70	1.00	0.67	1.00	0.56	0.57	0.58	0.66	0.33	0.72	1.00	1.00	0.56
8805 (TRIM24)	1.00	0.52	0.48	0.64	0.50	0.50	0.37	1.00	0.51	0.67	0.71	0.56	0.62	0.73	0.64	0.62	0.64	0.55	0.63	0.56	0.59	0.67	0.53	0.50	0.60	0.54	0.55	0.60	0.65	0.62	1.00	0.65	0.69	0.53	0.26	0.50	0.57	1.00	0.52	0.56	1.00	0.48	0.65	0.72	0.46	0.45	1.00	1.00	0.48
5908 (RAP1B)	1.00	0.51	0.95	0.40	0.48	0.49	0.20	1.00	0.54	0.44	1.00	0.64	0.49	0.59	0.41	0.41	0.43	0.55	0.62	0.55	0.63	0.46	0.56	0.49	0.50	0.51	0.55	0.65	0.47	0.47	1.00	0.59	0.47	0.52	0.26	0.99	0.55	1.00	0.49	0.57	0.48	1.00	0.44	0.51	0.30	0.46	1.00	1.00	0.64
5594 (MAPK1)	1.00	0.50	0.45	0.82	0.47	0.47	0.58	1.00	0.47	0.84	0.71	0.53	0.76	0.77	0.86	0.80	0.98	0.53	0.61	0.53	0.60	0.91	0.51	0.47	0.49	0.52	0.53	0.60	0.60	0.87	1.00	0.58	0.71	0.50	0.26	0.47	0.54	1.00	0.52	0.58	0.65	0.44	1.00	0.82	0.35	0.50	1.00	1.00	0.49
1445 (CSK)	1.00	0.57	0.55	0.78	0.56	0.56	0.50	1.00	0.54	0.81	0.71	0.61	0.79	0.85	0.81	0.72	0.81	0.63	0.69	0.62	0.65	0.86	0.59	0.56	0.57	0.56	0.61	0.68	0.65	0.79	1.00	0.65	0.81	0.58	0.26	0.54	0.62	1.00	0.58	0.66	0.72	0.51	0.82	1.00	0.38	0.50	1.00	1.00	0.53
80853 (KDM7A)	0.69	0.31	0.30	0.31	0.29	0.30	0.23	0.69	0.30	0.38	0.49	0.32	0.34	0.41	0.31	0.30	0.35	0.32	0.37	0.33	0.37	0.36	0.31	0.30	0.31	0.37	0.32	0.37	0.36	0.31	0.69	0.36	0.35	0.31	0.21	0.31	0.34	0.69	0.35	0.33	0.46	0.30	0.35	0.38	1.00	0.26	0.69	0.69	0.32
8546 (AP3B1)	0.82	0.57	0.47	0.38	0.59	0.58	0.22	0.82	0.52	0.44	0.58	0.70	0.53	0.52	0.43	0.40	0.53	0.71	0.65	0.60	0.66	0.47	0.66	0.58	0.50	0.54	0.70	0.58	0.49	0.58	0.82	0.61	0.42	0.61	0.21	0.51	0.56	0.82	0.52	0.72	0.45	0.46	0.50	0.50	0.26	1.00	0.82	0.82	0.42
57085 (AGTRAP)	1.00	1.00	1.00	1.00	1.00	1.00	0.34	1.00	1.00	1.00	0.71	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.26	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.69	0.82	1.00	1.00	1.00
5526 (PPP2R5B)	1.00	1.00	1.00	1.00	1.00	1.00	0.34	1.00	1.00	1.00	0.71	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.26	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.69	0.82	1.00	1.00	1.00
5536 (PPP5C)	1.00	0.50	0.65	0.44	0.47	0.70	0.36	1.00	0.47	0.48	0.71	0.51	0.59	0.57	0.44	0.45	0.46	0.51	0.58	0.52	0.59	0.50	0.49	0.70	0.50	0.50	0.51	0.60	0.50	0.46	1.00	0.56	0.47	0.50	0.34	0.63	0.54	1.00	0.50	0.56	0.48	0.64	0.49	0.53	0.32	0.42	1.00	1.00	1.00

Association with High Altitude

Protein Official symbol	Source Organism	Tissue of Expression	Level of hypoxia	Altitude	Duration of experiment	Level of expression	Fold change	Experiment details	geographical location	ethnicity of the patients	Control group	Control (Fold change)	Reference (PMID)
ARAF	Human	Blood	-	3250 m	4 day	upregulated	2.33	Microarray	Himalayas	Indians	1	Sea level healthy individuals	24465776
ARAF	Human	Blood	-	3250 m	4 day	upregulated	2.33	Microarray	Himalayas	Indians	1	Sea level healthy individuals	24465776

Association with TF

TF	TF Entrez	Gene	Gene Entrez	Type	PMID	Database
FOS	2353	ARAF	369	proximal_filtered	22955619	TRANSFAC
NFYB	4801	ARAF	369	proximal_filtered	22955619	TRANSFAC

Association with miRNA

miRTarBase ID	miRNA	Species (miRNA)	Protein Official Symbol	Human Entrez ID	Species (Target Gene)	Experiments	Support Type	References (PMID)
MIRT004929	hsa-miR-124-3p	Homo sapiens	ARAF	369	Homo sapiens	Microarray	Functional MTI (Weak)	15685193
MIRT004929	hsa-miR-124-3p	Homo sapiens	ARAF	369	Homo sapiens	Microarray	Functional MTI (Weak)	18668037
MIRT043358	hsa-miR-331-3p	Homo sapiens	ARAF	369	Homo sapiens	CLASH	Functional MTI (Weak)	23622248

Gene Ontology

ID	GO ID	GO Term	GO Type
369	GO:0033138	positive regulation of peptidyl-serine phosphorylation	GOTERM_BP_DIRECT
369	GO:0035556	intracellular signal transduction	GOTERM_BP_DIRECT
369	GO:0004674	protein kinase activity	GOTERM_MF_DIRECT
369	GO:0046872	cadmium ion binding	GOTERM_MF_DIRECT
369	GO:0000165	MAPK cascade	GOTERM_BP_DIRECT
369	GO:0005057	scavenger receptor activity	GOTERM_MF_DIRECT
369	GO:0004709	MAP kinase kinase activity	GOTERM_MF_DIRECT
369	GO:0005515	protein binding	GOTERM_MF_DIRECT
369	GO:0032006	regulation of TOR signaling	GOTERM_BP_DIRECT
369	GO:0043066	negative regulation of apoptotic process	GOTERM_BP_DIRECT
369	GO:0004672	procollagen-proline 4-dioxygenase activity	GOTERM_MF_DIRECT
369	GO:0006464	cellular protein modification process	GOTERM_BP_DIRECT
369	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	GOTERM_BP_DIRECT
369	GO:0005524	tropomyosin binding	GOTERM_MF_DIRECT
369	GO:0005739	mitochondrion	GOTERM_CC_DIRECT
369	GO:0005829	cytosol	GOTERM_CC_DIRECT
369	GO:0005622	intracellular	GOTERM_CC_DIRECT

Pathways

Human Entrez ID	KEGG ID	KEGG Term
369	hsa04012	ErbB signaling pathway
369	hsa04068	FoxO signaling pathway
369	hsa04270	Vascular smooth muscle contraction
369	hsa04650	Natural killer cell mediated cytotoxicity
369	hsa04720	Long-term potentiation
369	hsa04726	Serotonergic synapse
369	hsa04914	Progesterone-mediated oocyte maturation
369	hsa04730	Long-term depression
369	hsa04810	Regulation of actin cytoskeleton
369	hsa04910	Insulin signaling pathway
369	hsa05034	Alcoholism
369	hsa05160	Hepatitis C
369	hsa05200	Pathways in cancer
369	hsa05210	Colorectal cancer
369	hsa05211	Renal cell carcinoma
369	hsa05215	Prostate cancer
369	hsa05212	Pancreatic cancer
369	hsa05205	Proteoglycans in cancer
369	hsa05219	Bladder cancer
369	hsa05218	Melanoma
369	hsa05223	Non-small cell lung cancer
369	hsa05220	Chronic myeloid leukemia
369	hsa05221	Acute myeloid leukemia
369	hsa05213	Endometrial cancer
369	hsa05214	Glioma

Association with Disease

Protein Official Symbol	Human Entrez ID	Disease Name	Disease Id	Disease Semantic Type	Semantic score	DSI	DPI	Disease Type
ARAF	369	Adenocarcinoma of lung (disorder)	C0152013	Neoplastic Process	0.41	0.701	0.414	disease
ARAF	369	Breast Carcinoma	C0678222	Neoplastic Process	0.3	0.701	0.414	disease
ARAF	369	Mammary Neoplasms	C1458155	Neoplastic Process	0.3	0.701	0.414	group
ARAF	369	Malignant neoplasm of breast	C0006142	Neoplastic Process	0.3	0.701	0.414	disease
ARAF	369	Mammary Neoplasms, Human	C1257931	Neoplastic Process	0.3	0.701	0.414	group
ARAF	369	Adenocarcinoma of large intestine	C1319315	Neoplastic Process	0.3	0.701	0.414	disease

Association with Drug

Protein Official Symbol	Human Entrez ID	drug_claim_primary_name	drug_name	drug_chembl_id	interaction_types
ARAF	369	1096708-71-2	MLN-2480	CHEMBL3348923	inhibitor
ARAF	369	BGB-283	BGB-283	CHEMBL3545246	inhibitor
ARAF	369	LGX818	ENCORAFENIB	CHEMBL3301612	inhibitor
ARAF	369	LY3009120	LY-3009120	CHEMBL3545195	inhibitor
ARAF	369	LY-3009120	LY-3009120	CHEMBL3545195	inhibitor
ARAF	369	MLN-2480	MLN-2480	CHEMBL3348923	inhibitor
ARAF	369	REGORAFENIB	REGORAFENIB	CHEMBL1946170	inhibitor
ARAF	369	Sorafenib	SORAFENIB	CHEMBL1336	None
ARAF	369	Sorafenib	SORAFENIB	CHEMBL1336	None
ARAF	369	SORAFENIB	SORAFENIB	CHEMBL1336	None
ARAF	369	SORAFENIB	SORAFENIB	CHEMBL1336	None
ARAF	369	SORAFENIB	SORAFENIB	CHEMBL1336	inhibitor
ARAF	369	TRAMETINIB	TRAMETINIB	CHEMBL2103875	None
ARAF	369	XL281	XL-281	CHEMBL3545027	None
ARAF	369	XL281	XL-281	CHEMBL3545027	inhibitor