ALTITUDEOMICSDB

Tyrosine-protein kinase CSK

AltitudeomicsDB

Protein Official symbol	CSK
Aliases	CSK
Chromosomal Location	15
Length	450
Uniprot ID	P41240
EC number	2.7.10.2
Protein family Information(Pfam)	PF07714;PF00017;PF00018;
PDB id	1BYG;1CSK;3D7T;3D7U;3EAC;3EAZ;
InterPro ID	IPR035027;IPR011009;IPR000719;IPR017441;IPR001245;IPR000980;IPR036860;IPR036028;IPR001452;IPR008266;IPR020635;
dbSNP	rs34866753 rs34616395 rs35556162

Protein Protein Interaction

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AltitudeomicsDB

Protein 1	Protein 2	Combine Score
EGFR	EGF	0.997
HRAS	EGFR	0.997
PXN	VCL	0.997
PTK2	PXN	0.997
EGFR	KRAS	0.996
PTPN11	GAB1	0.995
CD3E	CD3D	0.995
SRC	PXN	0.994
VEGFA	EGF	0.993
BCAR1	PXN	0.993
BCAR1	SRC	0.992
CD247	CD3D	0.992
CD3G	CD3E	0.991
SRC	EGF	0.99
BCAR1	PTK2	0.99
SHC1	EGFR	0.989
FN1	EGF	0.988
VEGFA	FN1	0.988
SRC	VCL	0.987
PTPN11	MAPK3	0.987
CD247	ZAP70	0.987
VEGFA	SRC	0.987
HRAS	MAP2K1	0.986
TLN1	VCL	0.986
LCK	CD3D	0.985
CD247	LCK	0.985
CD3E	ZAP70	0.984
PTPN11	EGFR	0.984
CD3D	ZAP70	0.984
PTK2	VCL	0.984
PTPN11	MAPK1	0.983
CD3G	CD3D	0.983
FN1	VCL	0.983
HRAS	SRC	0.983
FN1	PXN	0.983
CD247	CD3E	0.983
CD3G	CD247	0.982
PAG1	CSK	0.982
PTPN11	PXN	0.982
HRAS	MAPK3	0.981
SHC1	EGF	0.981
RHOA	VCL	0.981
PTPN22	CSK	0.981
CD3E	LCK	0.981
HRAS	MAP2K2	0.98
HLA-DRB1	PTPN22	0.98
RHOA	PXN	0.98
BCAR1	FYN	0.98
NRAS	MAP2K1	0.979
RHOA	MAPK1	0.979
BCAR1	VCL	0.979
RHOA	IQGAP1	0.979
HRAS	MAPK1	0.979
HRAS	PTPN11	0.979
VEGFA	EGFR	0.979
MAP2K1	KRAS	0.979
MAPK3	KRAS	0.979
PTPN22	ZAP70	0.978
HRAS	EGF	0.977
PTPN22	LCK	0.977
RHOA	SRC	0.977
BCAR1	CRKL	0.977
VEGFA	RHOA	0.977
TLN1	PXN	0.976
NRAS	PTPN11	0.976
EGF	KRAS	0.976
FN1	PTK2	0.975
SRC	FN1	0.975
PXN	MAPK1	0.974
NRAS	EGFR	0.974
SRC	GAB1	0.973
NRAS	MAPK3	0.973
RHOA	PTK2	0.973
KRAS	MAPK1	0.973
PECAM1	SRC	0.972
PTPN11	KRAS	0.972
LYN	PTPN6	0.972
RHOA	MAPK3	0.972
SHC1	MAPK3	0.971
HCK	FGR	0.971
SRC	KRAS	0.971
LYN	SHC1	0.97
NRAS	MAP2K2	0.97
FN1	MAPK3	0.97
NRAS	MAPK1	0.97
MAP2K2	KRAS	0.97
PECAM1	PTPN11	0.969
HRAS	RASA1	0.968
EGFR	GAB1	0.968
ITGB3	TLN1	0.968
SHC1	MAPK1	0.968
CD3G	LCK	0.968
PTK2	PTPN11	0.968
SHC1	LCK	0.968
ARRB1	MAPK1	0.968
RHOA	PTPN11	0.967
BCAR1	FN1	0.967
FYN	PXN	0.967
PXN	MAPK3	0.967
CD3G	ZAP70	0.967
HRAS	FYN	0.967
PTPN11	MAP2K1	0.966
LYN	CD79B	0.966
HRAS	SHC1	0.965
IQGAP1	MAPK1	0.965
ARRB1	MAPK3	0.965
APBB1IP	TLN1	0.965
RHOA	EGFR	0.965
FN1	MAPK1	0.965
PXN	CSK	0.964
IQGAP1	MAPK3	0.964
SRC	IQGAP1	0.964
SHC1	FYN	0.964
RHOA	EGF	0.964
HCK	PXN	0.964
LYN	BCAR1	0.964
SRC	TNS1	0.964
CD79B	FYN	0.963
VEGFA	PTK2	0.963
LCK	ZAP70	0.963
RHOA	FYN	0.963
ITGB3	FN1	0.962
LYN	PAG1	0.962
PTK2	TLN1	0.962
PTPN11	MAP2K2	0.961
CD79B	BLK	0.961
FYN	KRAS	0.961
PXN	TNS1	0.96
HRAS	IQGAP1	0.96
PXN	EGF	0.959
PECAM1	ITGB3	0.959
EGFR	PXN	0.959
RASA1	EGF	0.959
RASA1	KRAS	0.959
FYN	CRKL	0.958
SHC1	PTK2	0.958
HRAS	FN1	0.958
RASA1	DOK1	0.958
MAPK3	VCL	0.958
ARRB2	MAPK3	0.958
SHC1	MAP2K1	0.957
PTPN11	EGF	0.957
VCL	TNS1	0.957
LYN	PTPN11	0.957
RHOA	BCAR1	0.957
SHC1	KRAS	0.956
SHC1	GAB1	0.956
IQGAP1	MAP2K2	0.956
RHOA	TNS1	0.956
BCAR1	CSK	0.956
CRKL	PXN	0.956
DOK1	CSK	0.956
BCAR1	PTPN11	0.955
APBB1IP	VCL	0.955
ARRB1	SRC	0.955
SRC	PAG1	0.955
ITGB3	VCL	0.955
FYN	EGF	0.954
FYN	VCL	0.954
FYN	PAG1	0.954
FN1	KRAS	0.953
PTK2	TNS1	0.952
HRAS	PTK2	0.952
BCAR1	TNS1	0.952
PECAM1	LYN	0.952
VEGFA	PXN	0.951
LYN	CRKL	0.951
RHOA	RASA1	0.951
FN1	TLN1	0.95
LCK	PAG1	0.95
FN1	MAP2K1	0.95
CD247	FYN	0.95
EGF	CSK	0.95
NRAS	RASA1	0.95
HRAS	LCK	0.949
RASA1	MAPK3	0.949
YES1	HRAS	0.949
MAPK1	VCL	0.949
SHC1	DOK1	0.949
LYN	PXN	0.948
MAP2K1	MAPK3	0.948
MAPK3	MAP2K2	0.948
IQGAP1	VCL	0.948
RHOA	TLN1	0.948
PTK2	KRAS	0.948
SRC	DOK1	0.948
SRC	TLN1	0.947
MAP2K1	MAPK1	0.947
BCAR1	TLN1	0.947
VEGFA	SHC1	0.947
SRC	NRAS	0.947
ITGB3	SRC	0.946
MAP2K2	MAPK1	0.946
YES1	PXN	0.945
MAPK3	GAB1	0.945
SHC1	ZAP70	0.945
EGF	GAB1	0.945
ITGB3	PTK2	0.944
SHC1	RHOA	0.944
VEGFA	PTPN11	0.944
NRAS	EGF	0.944
ITGB3	PXN	0.944
SRC	PTPN11	0.943
LYN	HRAS	0.943
EGFR	RASA1	0.943
RHOA	CSK	0.943
CSK	VCL	0.943
YES1	VCL	0.943
RASA1	MAPK1	0.943
MAP2K1	IQGAP1	0.942
SHC1	SRC	0.941
SRC	MAPK3	0.941
ARRB2	SRC	0.941
HCK	PTPN11	0.941
YES1	KRAS	0.941
LYN	EGF	0.941
FGR	PXN	0.941
VEGFA	FYN	0.941
HRAS	VCL	0.94
LCK	EGF	0.94
SHC1	RASA1	0.94
YES1	BCAR1	0.94
TLN1	IQGAP1	0.94
SRC	MAPK1	0.94
PECAM1	PTK2	0.94
LCK	PXN	0.94
YES1	EGF	0.939
VEGFA	BCAR1	0.939
VEGFA	ITGB3	0.939
YES1	RHOA	0.939
FN1	CSK	0.939
ITGB3	RHOA	0.939
ZAP70	PAG1	0.939
LCK	KRAS	0.939
PECAM1	PXN	0.938
SHC1	PTPN6	0.938
LYN	DOK1	0.938
APBB1IP	SRC	0.938
SHC1	MAP2K2	0.938
ARRB2	MAPK1	0.938
PECAM1	FYN	0.938
VEGFA	CSK	0.937
EGFR	MAPK3	0.937
EGFR	MAPK1	0.937
PTPN11	CSK	0.937
BCAR1	LCK	0.937
FYN	PTPN11	0.937
LYN	RHOA	0.937
PTPN6	FYN	0.937
CRKL	PTK2	0.937
ARRB1	EGFR	0.937
HCK	EGF	0.937
LYN	MAPK3	0.937
CD247	HLA-DRB1	0.937
SRC	MAP2K1	0.936
ARRB1	MAP2K1	0.936
PTPN6	CD79B	0.936
PTPN11	PAG1	0.936
RHOA	LCK	0.936
GAB1	MAPK1	0.935
KRAS	VCL	0.935
PTPN6	LCK	0.934
HCK	BCAR1	0.934
MAP2K1	VCL	0.934
LYN	KRAS	0.934
TLN1	TNS1	0.934
HRAS	GAB1	0.933
FYN	MAPK1	0.933
SRC	RASA1	0.933
PTK2	MAPK3	0.932
IQGAP1	KRAS	0.932
HCK	HRAS	0.932
FGR	EGF	0.932
MAPK3	CSK	0.932
FYN	DOK1	0.932
SHC1	PTPN11	0.932
ARRB2	MAP2K2	0.932
HRAS	FGR	0.932
CRKL	VCL	0.932
GAB1	CSK	0.932
APBB1IP	FN1	0.932
FN1	IQGAP1	0.931
HRAS	CSK	0.931
NRAS	LCK	0.931
SRC	EGFR	0.931
ARRB1	EGF	0.93
PTPN6	CRKL	0.93
PTPN6	CD247	0.93
SRC	CRKL	0.93
CD3E	FYN	0.93
LCK	MAPK3	0.93
PTK2	MAPK1	0.929
LYN	MAPK1	0.929
PXN	PAG1	0.929
CRKL	GAB1	0.929
ITGB3	MAPK3	0.928
PECAM1	LCK	0.928
YES1	EGFR	0.928
PTK2	RASA1	0.928
NRAS	FN1	0.928
LCK	MAPK1	0.928
CSK	MAPK1	0.928
HCK	LYN	0.928
SHC1	NRAS	0.928
LCK	RASA1	0.927
SRC	MAP2K2	0.927
CD3G	FYN	0.927
PTPN6	ZAP70	0.927
PTPN11	LCK	0.927
PTPN6	HLA-DRB1	0.926
ARRB2	MAP2K1	0.926
SRC	PTK2	0.926
HLA-DRB1	CD3D	0.926
CRKL	PTPN11	0.926
NRAS	FYN	0.926
BCAR1	FGR	0.926
ZAP70	BLK	0.926
NRAS	PTK2	0.925
VEGFA	IQGAP1	0.925
KRAS	CSK	0.925
PRKACB	MAPK1	0.925
CSK	TNS1	0.925
EGF	BLK	0.925
CD3G	HLA-DRB1	0.925
SHC1	CSK	0.924
ITGB3	MAPK1	0.924
HRAS	RHOA	0.924
RHOA	KRAS	0.924
FYN	EGFR	0.924
ARRB1	KRAS	0.924
YES1	NRAS	0.924
BLK	CSK	0.924
LCK	DOK1	0.923
LCK	MAP2K1	0.923
FYN	ZAP70	0.923
YES1	DOK1	0.923
CD3E	HLA-DRB1	0.923
CD247	PTPN11	0.923
APBB1IP	PTK2	0.923
LYN	EGFR	0.923
ARRB2	EGF	0.923
CD247	CSK	0.923
RASA1	CSK	0.923
HLA-DRB1	LCK	0.922
ITGB3	HRAS	0.922
HLA-DRB1	ZAP70	0.922
ITGB3	BCAR1	0.922
HCK	EGFR	0.922
LCK	VCL	0.922
MAP2K1	GAB1	0.922
HRAS	DOK1	0.922
ARRB2	EGFR	0.922
LCK	EGFR	0.922
SRC	ZAP70	0.922
PXN	GAB1	0.922
CD247	PAG1	0.921
PTPN6	CSK	0.921
MAP2K1	CSK	0.921
RHOA	NRAS	0.921
ARRB1	FN1	0.921
HRAS	ARRB2	0.921
PXN	BLK	0.921
FGR	EGFR	0.921
PRKACB	MAPK3	0.921
YES1	PTPN11	0.92
ARRB1	CSK	0.92
FYN	PTK2	0.92
ZAP70	CSK	0.92
NRAS	IQGAP1	0.92
FN1	MAP2K2	0.92
FGR	ZAP70	0.92
SRC	CSK	0.92
FYN	TLN1	0.92
PRKACG	MAPK1	0.92
PRKACG	MAPK3	0.92
HCK	ARRB1	0.92
ARRB2	KRAS	0.92
VEGFA	PTPN6	0.919
ARRB1	HRAS	0.919
CD3G	PTPN22	0.919
LYN	ZAP70	0.919
HCK	ZAP70	0.918
EGFR	BLK	0.918
NRAS	VCL	0.918
MAP2K2	CSK	0.918
YES1	PTK2	0.918
ARRB1	FGR	0.918
LYN	RASA1	0.918
CRKL	TLN1	0.918
LYN	FGR	0.918
LYN	NRAS	0.918
NRAS	CSK	0.917
APBB1IP	CSK	0.917
FYN	RASA1	0.917
CD3G	PAG1	0.917
FYN	CSK	0.917
CRKL	TNS1	0.917
BCAR1	APBB1IP	0.917
LCK	CSK	0.917
ITGB3	KRAS	0.917
PECAM1	BCAR1	0.917
ITGB3	APBB1IP	0.917
HCK	CRKL	0.917
PTPN22	CD3D	0.917
YES1	CRKL	0.917
HCK	CSK	0.917
CRKL	CSK	0.916
HRAS	TLN1	0.916
EGFR	CSK	0.916
PTK2	CSK	0.916
TLN1	MAPK1	0.916
YES1	MAPK1	0.916
LYN	CSK	0.916
TLN1	MAPK3	0.916
PECAM1	CSK	0.915
SHC1	CD247	0.915
VEGFA	GAB1	0.915
ARRB2	FN1	0.915
LYN	PTK2	0.915
ARRB1	IQGAP1	0.915
LYN	ARRB1	0.915
LCK	BLK	0.914
ITGB3	SHC1	0.914
HLA-DRB1	CSK	0.914
LCK	MAP2K2	0.914
HLA-DRB1	PAG1	0.914
TLN1	CSK	0.913
PRKACB	FYN	0.913
FYN	CD3D	0.913
ITGB3	CSK	0.913
HCK	DOK1	0.913
RHOA	PRKACB	0.913
CD79B	CSK	0.913
PRKACG	CSK	0.912
BCAR1	BLK	0.912
FGR	CSK	0.912
CD3D	CSK	0.912
HCK	RASA1	0.911
PECAM1	PTPN6	0.911
CD3E	CSK	0.911
CD3G	CSK	0.911
PRKACB	CSK	0.911
YES1	ZAP70	0.911
HCK	PTK2	0.911
FGR	PTK2	0.911
PRKACG	FYN	0.911
PTPN6	CD3E	0.911
IQGAP1	CSK	0.911
APBB1IP	MAPK3	0.911
FGR	DOK1	0.91
ITGB3	MAP2K1	0.91
ARRB2	FGR	0.91
EGFR	PAG1	0.91
YES1	CSK	0.91
PRKACB	TLN1	0.91
PTK2	LCK	0.91
MAP2K2	VCL	0.91
SHC1	TLN1	0.909
GAB1	PAG1	0.909
CD3D	PAG1	0.909
HLA-DRB1	PTPN11	0.909
CD3G	PTPN6	0.909
ARRB2	CSK	0.909
BLK	DOK1	0.909
CD3E	PTPN22	0.909
HRAS	APBB1IP	0.909
PTPN6	CD3D	0.908
PRKACG	TLN1	0.908
SHC1	APBB1IP	0.908
YES1	RASA1	0.908
ARRB2	IQGAP1	0.907
FGR	BLK	0.907
FYN	LCK	0.907
LYN	LCK	0.907
HLA-DRB1	FYN	0.907
PRKACB	IQGAP1	0.907
HCK	ARRB2	0.906
HCK	LCK	0.906
ARRB2	APBB1IP	0.906
SRC	LCK	0.906
HCK	BLK	0.906
RASA1	BLK	0.906
YES1	PECAM1	0.906
PTPN6	VCL	0.906
ITGB3	NRAS	0.906
PTK2	BLK	0.906
PRKACG	IQGAP1	0.906
APBB1IP	IQGAP1	0.906
FGR	LCK	0.906
TLN1	KRAS	0.905
HCK	FYN	0.905
APBB1IP	MAP2K1	0.905
ARRB1	VCL	0.905
LYN	SRC	0.905
EGF	PAG1	0.905
APBB1IP	MAPK1	0.905
LYN	FYN	0.905
FGR	RASA1	0.905
RHOA	PRKACG	0.905
ITGB3	IQGAP1	0.905
HCK	SRC	0.905
CD79B	DOK1	0.905
FYN	BLK	0.904
PRKACG	PRKACB	0.904
ARRB1	TLN1	0.904
CD3G	LYN	0.904
SHC1	CD79B	0.904
TLN1	MAP2K1	0.904
NRAS	KRAS	0.904
ARRB2	CD3D	0.904
ARRB1	ARRB2	0.904
PRKACB	FN1	0.904
LYN	ARRB2	0.904
APBB1IP	KRAS	0.904
ARRB1	MAP2K2	0.904
PTPN6	PTPN11	0.903
APBB1IP	MAP2K2	0.903
CD3D	EGFR	0.903
ARRB1	NRAS	0.903
CD3G	EGF	0.903
LYN	BLK	0.903
SRC	BLK	0.903
CD3E	PTPN11	0.903
SRC	FYN	0.903
HCK	CD3G	0.903
ARRB2	NRAS	0.903
YES1	HCK	0.902
CD3G	ARRB2	0.902
CD3G	PTPN11	0.902
YES1	LCK	0.902
VEGFA	PECAM1	0.902
MAP2K1	MAP2K2	0.902
CD3G	FGR	0.902
FGR	FYN	0.902
HRAS	NRAS	0.902
PRKACB	PTK2	0.902
CD3G	EGFR	0.902
ARRB1	CD3D	0.902
CD3D	EGF	0.902
YES1	LYN	0.902
MAPK3	MAPK1	0.902
FGR	SRC	0.902
HRAS	KRAS	0.902
CD3G	SHC1	0.902
PRKACG	PTK2	0.902
PTPN11	CD3D	0.902
APBB1IP	NRAS	0.902
ARRB2	VCL	0.901
YES1	FYN	0.901
CD3G	ARRB1	0.901
ARRB1	APBB1IP	0.901
YES1	SRC	0.901
YES1	BLK	0.901
NRAS	TLN1	0.901
TLN1	MAP2K2	0.901
HCK	GAB1	0.901
ARRB2	TLN1	0.901
CD79B	PAG1	0.901
ARRB2	FYN	0.901
YES1	FGR	0.901
CD79B	RASA1	0.9
ITGB3	MAP2K2	0.9
YES1	CD3G	0.9
ITGB3	ARRB1	0.9
SHC1	HLA-DRB1	0.9
PRKACG	CD247	0.9
PRKACB	CD247	0.9
SHC1	CD3D	0.9
SHC1	CD3E	0.9
PRKACB	PXN	0.9
CD3E	PAG1	0.9
ITGB3	ARRB2	0.9
PRKACG	PXN	0.9

Gene Ontology Semantic Similarity

Download Tab separated file

#	1956 (EGFR)	3265 (HRAS)	5829 (PXN)	5747 (PTK2)	5781 (PTPN11)	916 (CD3E)	6714 (SRC)	7422 (VEGFA)	9564 (BCAR1)	919 (CD247)	917 (CD3G)	6464 (SHC1)	2335 (FN1)	7094 (TLN1)	3932 (LCK)	915 (CD3D)	55824 (PAG1)	387 (RHOA)	26191 (PTPN22)	3123 (HLA-DRB1)	4893 (NRAS)	5604 (MAP2K1)	5595 (MAPK3)	1950 (EGF)	3845 (KRAS)	5175 (PECAM1)	4067 (LYN)	3055 (HCK)	5605 (MAP2K2)	3690 (ITGB3)	408 (ARRB1)	2534 (FYN)	8826 (IQGAP1)	54518 (APBB1IP)	974 (CD79B)	5921 (RASA1)	409 (ARRB2)	7414 (VCL)	1399 (CRKL)	1796 (DOK1)	7525 (YES1)	5594 (MAPK1)	1445 (CSK)	2268 (FGR)	7535 (ZAP70)	5777 (PTPN6)	2549 (GAB1)	5567 (PRKACB)	640 (BLK)	5568 (PRKACG)	7145 (TNS1)
1956 (EGFR)	1.00	0.44	0.54	0.74	0.55	0.63	0.73	0.56	0.48	0.52	0.53	0.55	0.55	0.51	0.71	0.49	0.48	0.46	0.51	0.28	0.50	0.65	0.67	0.74	0.50	0.48	0.63	0.64	0.62	0.62	0.58	0.73	0.57	1.00	0.48	0.49	0.57	0.58	0.56	1.00	0.68	0.67	0.66	0.65	0.62	0.50	0.59	0.61	0.65	0.27	0.49
3265 (HRAS)	0.44	1.00	0.61	0.47	0.43	0.55	0.57	0.59	0.55	0.58	0.42	0.54	0.62	0.55	0.56	0.36	0.56	0.90	0.53	0.31	0.55	0.48	0.48	0.44	0.55	0.55	0.47	0.49	0.44	0.59	0.53	0.50	0.53	1.00	0.55	0.63	0.63	0.63	0.59	1.00	0.55	0.45	0.56	0.52	0.62	0.44	0.45	0.56	0.48	0.10	0.54
5829 (PXN)	0.54	0.61	1.00	0.62	0.52	0.67	0.62	0.64	0.77	0.75	0.54	0.62	0.68	0.75	0.65	0.47	0.76	0.64	0.64	0.41	0.77	0.56	0.65	0.55	0.77	0.77	0.60	0.66	0.57	0.67	0.64	0.60	0.65	1.00	0.77	0.63	0.78	0.79	0.71	1.00	0.70	0.61	0.66	0.65	0.58	0.57	0.62	0.53	0.67	0.10	0.74
5747 (PTK2)	0.74	0.47	0.62	1.00	0.61	0.60	0.80	0.56	0.62	0.61	0.39	0.62	0.57	0.54	0.81	0.34	0.58	0.56	0.55	0.29	0.53	0.75	0.75	0.74	0.53	0.53	0.74	0.78	0.70	0.59	0.55	0.78	0.62	1.00	0.53	0.50	0.61	0.62	0.55	1.00	0.80	0.75	0.79	0.81	0.73	0.52	0.63	0.66	0.79	0.38	0.51
5781 (PTPN11)	0.55	0.43	0.52	0.61	1.00	0.56	0.72	0.53	0.53	0.54	0.40	0.58	0.55	0.51	0.80	0.31	0.54	0.51	0.73	0.28	0.46	0.57	0.58	0.56	0.46	0.46	0.57	0.62	0.53	0.57	0.48	0.60	0.52	1.00	0.46	0.51	0.56	0.54	0.60	1.00	0.65	0.57	0.62	0.67	0.56	0.73	0.73	0.52	0.56	0.24	0.44
916 (CD3E)	0.63	0.55	0.67	0.60	0.56	1.00	0.62	0.67	0.73	0.77	0.89	0.63	0.66	0.67	0.65	0.71	0.65	0.64	0.66	0.38	0.65	0.54	0.58	0.61	0.65	0.73	0.55	0.59	0.54	0.70	0.60	0.57	0.64	1.00	0.73	0.57	0.72	0.68	0.65	1.00	0.63	0.55	0.64	0.66	0.53	0.65	0.56	0.50	0.59	0.09	0.63
6714 (SRC)	0.73	0.57	0.62	0.80	0.72	0.62	1.00	0.64	0.61	0.61	0.45	0.64	0.68	0.65	0.85	0.39	0.66	0.58	0.61	0.33	0.59	0.78	0.77	0.74	0.59	0.59	0.83	0.81	0.74	0.67	0.60	0.81	0.61	1.00	0.59	0.60	0.68	0.65	0.67	1.00	0.84	0.77	0.80	0.82	0.76	0.56	0.76	0.73	0.81	0.30	0.60
7422 (VEGFA)	0.56	0.59	0.64	0.56	0.53	0.67	0.64	1.00	0.62	0.69	0.58	0.63	0.72	0.62	0.63	0.52	0.63	0.59	0.59	0.34	0.62	0.56	0.60	0.61	0.62	0.67	0.61	0.64	0.56	0.76	0.60	0.64	0.59	1.00	0.67	0.62	0.69	0.65	0.64	1.00	0.65	0.58	0.62	0.63	0.57	0.55	0.57	0.54	0.64	0.10	0.61
9564 (BCAR1)	0.48	0.55	0.77	0.62	0.53	0.73	0.61	0.62	1.00	0.86	0.53	0.63	0.66	0.68	0.62	0.45	0.77	0.71	0.66	0.43	0.80	0.52	0.57	0.49	0.80	0.80	0.54	0.61	0.51	0.65	0.61	0.56	0.63	1.00	0.80	0.57	0.77	0.76	0.70	1.00	0.67	0.52	0.69	0.69	0.51	0.60	0.56	0.46	0.61	0.11	0.74
919 (CD247)	0.52	0.58	0.75	0.61	0.54	0.77	0.61	0.69	0.86	1.00	0.65	0.66	0.69	0.68	0.64	0.60	0.74	0.68	0.65	0.41	0.76	0.54	0.64	0.52	0.76	0.89	0.56	0.63	0.54	0.68	0.62	0.60	0.63	1.00	0.89	0.59	0.76	0.75	0.75	1.00	0.67	0.59	0.73	0.67	0.55	0.60	0.59	0.50	0.63	0.10	0.72
917 (CD3G)	0.53	0.42	0.54	0.39	0.40	0.89	0.45	0.58	0.53	0.65	1.00	0.50	0.54	0.55	0.49	0.77	0.52	0.44	0.44	0.36	0.55	0.40	0.46	0.51	0.55	0.67	0.43	0.47	0.41	0.56	0.46	0.44	0.45	0.69	0.67	0.44	0.61	0.52	0.52	0.69	0.49	0.43	0.49	0.50	0.40	0.48	0.43	0.36	0.48	0.08	0.51
6464 (SHC1)	0.55	0.54	0.62	0.62	0.58	0.63	0.64	0.63	0.63	0.66	0.50	1.00	0.66	0.61	0.64	0.39	0.61	0.58	0.57	0.35	0.59	0.52	0.53	0.63	0.59	0.59	0.59	0.65	0.51	0.63	0.62	0.66	0.62	1.00	0.59	0.64	0.68	0.63	0.65	1.00	0.67	0.51	0.58	0.67	0.56	0.58	0.54	0.49	0.60	0.09	0.57
2335 (FN1)	0.55	0.62	0.68	0.57	0.55	0.66	0.68	0.72	0.66	0.69	0.54	0.66	1.00	0.72	0.66	0.44	0.65	0.61	0.61	0.40	0.65	0.57	0.61	0.55	0.65	0.66	0.59	0.62	0.55	0.72	0.62	0.71	0.61	1.00	0.66	0.61	0.75	0.68	0.66	1.00	0.67	0.58	0.65	0.65	0.57	0.56	0.58	0.54	0.63	0.09	0.63
7094 (TLN1)	0.51	0.55	0.75	0.54	0.51	0.67	0.65	0.62	0.68	0.68	0.55	0.61	0.72	1.00	0.60	0.43	0.68	0.58	0.59	0.40	0.68	0.53	0.56	0.51	0.68	0.68	0.55	0.60	0.53	0.68	0.60	0.56	0.63	1.00	0.68	0.58	0.72	0.75	0.71	1.00	0.63	0.53	0.61	0.62	0.53	0.52	0.56	0.49	0.60	0.10	0.65
3932 (LCK)	0.71	0.56	0.65	0.81	0.80	0.65	0.85	0.63	0.62	0.64	0.49	0.64	0.66	0.60	1.00	0.40	0.62	0.59	0.66	0.33	0.58	0.73	0.76	0.71	0.58	0.59	0.79	0.82	0.68	0.64	0.58	0.78	0.61	1.00	0.59	0.61	0.67	0.61	0.64	1.00	0.83	0.76	0.81	0.84	0.75	0.66	0.70	0.69	0.79	0.27	0.57
915 (CD3D)	0.49	0.36	0.47	0.34	0.31	0.71	0.39	0.52	0.45	0.60	0.77	0.39	0.44	0.43	0.40	1.00	0.45	0.38	0.38	0.26	0.46	0.35	0.41	0.45	0.46	0.62	0.35	0.38	0.35	0.49	0.39	0.38	0.38	0.69	0.62	0.37	0.47	0.47	0.47	0.69	0.41	0.38	0.43	0.39	0.33	0.43	0.36	0.30	0.38	0.08	0.43
55824 (PAG1)	0.48	0.56	0.76	0.58	0.54	0.65	0.66	0.63	0.77	0.74	0.52	0.61	0.65	0.68	0.62	0.45	1.00	0.60	0.62	0.42	0.77	0.53	0.58	0.51	0.77	0.77	0.55	0.61	0.53	0.65	0.62	0.55	0.60	1.00	0.77	0.58	0.75	0.75	0.80	1.00	0.65	0.53	0.63	0.61	0.53	0.52	0.70	0.48	0.62	0.11	0.72
387 (RHOA)	0.46	0.90	0.64	0.56	0.51	0.64	0.58	0.59	0.71	0.68	0.44	0.58	0.61	0.58	0.59	0.38	0.60	1.00	0.60	0.33	0.59	0.48	0.51	0.46	0.59	0.60	0.49	0.52	0.47	0.61	0.55	0.52	0.59	1.00	0.60	0.65	0.66	0.65	0.61	1.00	0.58	0.47	0.60	0.60	0.59	0.54	0.48	0.54	0.52	0.10	0.58
26191 (PTPN22)	0.51	0.53	0.64	0.55	0.73	0.66	0.61	0.59	0.66	0.65	0.44	0.57	0.61	0.59	0.66	0.38	0.62	0.60	1.00	0.33	0.61	0.50	0.54	0.48	0.61	0.61	0.52	0.55	0.49	0.63	0.62	0.54	0.58	1.00	0.61	0.55	0.73	0.72	0.61	1.00	0.61	0.51	0.60	0.59	0.48	0.75	0.51	0.53	0.54	0.12	0.58
3123 (HLA-DRB1)	0.28	0.31	0.41	0.29	0.28	0.38	0.33	0.34	0.43	0.41	0.36	0.35	0.40	0.40	0.33	0.26	0.42	0.33	0.33	1.00	0.48	0.29	0.31	0.27	0.48	0.44	0.29	0.33	0.28	0.38	0.33	0.29	0.32	0.52	0.44	0.31	0.40	0.40	0.38	0.52	0.35	0.29	0.35	0.35	0.29	0.27	0.31	0.26	0.33	0.08	0.42
4893 (NRAS)	0.50	0.55	0.77	0.53	0.46	0.65	0.59	0.62	0.80	0.76	0.55	0.59	0.65	0.68	0.58	0.46	0.77	0.59	0.61	0.48	1.00	0.52	0.57	0.49	1.00	0.80	0.53	0.61	0.51	0.65	0.61	0.55	0.58	1.00	0.80	0.57	0.76	0.76	0.70	1.00	0.65	0.52	0.63	0.61	0.51	0.50	0.56	0.46	0.61	0.12	0.74
5604 (MAP2K1)	0.65	0.48	0.56	0.75	0.57	0.54	0.78	0.56	0.52	0.54	0.40	0.52	0.57	0.53	0.73	0.35	0.53	0.48	0.50	0.29	0.52	1.00	0.79	0.71	0.52	0.52	0.73	0.77	0.95	0.58	0.55	0.69	0.61	1.00	0.52	0.51	0.58	0.58	0.54	1.00	0.77	0.80	0.79	0.74	0.72	0.44	0.66	0.72	0.78	0.51	0.50
5595 (MAPK3)	0.67	0.48	0.65	0.75	0.58	0.58	0.77	0.60	0.57	0.64	0.46	0.53	0.61	0.56	0.76	0.41	0.58	0.51	0.54	0.31	0.57	0.79	1.00	0.64	0.57	0.59	0.76	0.77	0.77	0.63	0.54	0.70	0.55	1.00	0.59	0.50	0.64	0.63	0.61	1.00	0.79	0.99	0.85	0.73	0.71	0.46	0.69	0.78	0.79	0.57	0.54
1950 (EGF)	0.74	0.44	0.55	0.74	0.56	0.61	0.74	0.61	0.49	0.52	0.51	0.63	0.55	0.51	0.71	0.45	0.51	0.46	0.48	0.27	0.49	0.71	0.64	1.00	0.49	0.49	0.67	0.70	0.67	0.61	0.54	0.76	0.56	1.00	0.49	0.52	0.59	0.57	0.52	1.00	0.71	0.65	0.67	0.68	0.63	0.47	0.64	0.58	0.71	0.31	0.47
3845 (KRAS)	0.50	0.55	0.77	0.53	0.46	0.65	0.59	0.62	0.80	0.76	0.55	0.59	0.65	0.68	0.58	0.46	0.77	0.59	0.61	0.48	1.00	0.52	0.57	0.49	1.00	0.80	0.53	0.61	0.51	0.65	0.61	0.55	0.58	1.00	0.80	0.57	0.76	0.76	0.70	1.00	0.65	0.52	0.63	0.61	0.51	0.50	0.56	0.46	0.61	0.12	0.74
5175 (PECAM1)	0.48	0.55	0.77	0.53	0.46	0.73	0.59	0.67	0.80	0.89	0.67	0.59	0.66	0.68	0.59	0.62	0.77	0.60	0.61	0.44	0.80	0.52	0.59	0.49	0.80	1.00	0.54	0.61	0.51	0.65	0.62	0.56	0.58	1.00	1.00	0.57	0.76	0.76	0.72	1.00	0.66	0.53	0.65	0.61	0.52	0.50	0.57	0.46	0.61	0.11	0.74
4067 (LYN)	0.63	0.47	0.60	0.74	0.57	0.55	0.83	0.61	0.54	0.56	0.43	0.59	0.59	0.55	0.79	0.35	0.55	0.49	0.52	0.29	0.53	0.73	0.76	0.67	0.53	0.54	1.00	0.84	0.69	0.60	0.54	0.76	0.52	1.00	0.54	0.52	0.65	0.60	0.56	1.00	0.86	0.76	0.81	0.81	0.75	0.59	0.65	0.69	0.86	0.40	0.51
3055 (HCK)	0.64	0.49	0.66	0.78	0.62	0.59	0.81	0.64	0.61	0.63	0.47	0.65	0.62	0.60	0.82	0.38	0.61	0.52	0.55	0.33	0.61	0.77	0.77	0.70	0.61	0.61	0.84	1.00	0.73	0.63	0.58	0.77	0.55	1.00	0.61	0.61	0.71	0.66	0.68	1.00	0.97	0.76	0.83	0.93	0.90	0.54	0.68	0.68	0.96	0.46	0.58
5605 (MAP2K2)	0.62	0.44	0.57	0.70	0.53	0.54	0.74	0.56	0.51	0.54	0.41	0.51	0.55	0.53	0.68	0.35	0.53	0.47	0.49	0.28	0.51	0.95	0.77	0.67	0.51	0.51	0.69	0.73	1.00	0.58	0.55	0.66	0.62	1.00	0.51	0.50	0.59	0.59	0.54	1.00	0.74	0.78	0.73	0.70	0.67	0.43	0.62	0.69	0.74	0.51	0.49
3690 (ITGB3)	0.62	0.59	0.67	0.59	0.57	0.70	0.67	0.76	0.65	0.68	0.56	0.63	0.72	0.68	0.64	0.49	0.65	0.61	0.63	0.38	0.65	0.58	0.63	0.61	0.65	0.65	0.60	0.63	0.58	1.00	0.62	0.63	0.61	1.00	0.65	0.62	0.71	0.68	0.66	1.00	0.66	0.61	0.64	0.64	0.58	0.60	0.60	0.56	0.63	0.10	0.63
408 (ARRB1)	0.58	0.53	0.64	0.55	0.48	0.60	0.60	0.60	0.61	0.62	0.46	0.62	0.62	0.60	0.58	0.39	0.62	0.55	0.62	0.33	0.61	0.55	0.54	0.54	0.61	0.62	0.54	0.58	0.55	0.62	1.00	0.58	0.69	1.00	0.62	0.69	0.77	0.70	0.64	1.00	0.62	0.51	0.57	0.59	0.51	0.51	0.53	0.53	0.58	0.09	0.63
2534 (FYN)	0.73	0.50	0.60	0.78	0.60	0.57	0.81	0.64	0.56	0.60	0.44	0.66	0.71	0.56	0.78	0.38	0.55	0.52	0.54	0.29	0.55	0.69	0.70	0.76	0.55	0.56	0.76	0.77	0.66	0.63	0.58	1.00	0.56	1.00	0.56	0.57	0.67	0.60	0.58	1.00	0.79	0.70	0.73	0.76	0.69	0.49	0.67	0.63	0.78	0.27	0.53
8826 (IQGAP1)	0.57	0.53	0.65	0.62	0.52	0.64	0.61	0.59	0.63	0.63	0.45	0.62	0.61	0.63	0.61	0.38	0.60	0.59	0.58	0.32	0.58	0.61	0.55	0.56	0.58	0.58	0.52	0.55	0.62	0.61	0.69	0.56	1.00	1.00	0.58	0.68	0.66	0.65	0.62	1.00	0.59	0.53	0.58	0.59	0.51	0.55	0.53	0.53	0.54	0.09	0.57
54518 (APBB1IP)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.69	1.00	1.00	1.00	1.00	0.69	1.00	1.00	1.00	0.52	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.13	1.00
974 (CD79B)	0.48	0.55	0.77	0.53	0.46	0.73	0.59	0.67	0.80	0.89	0.67	0.59	0.66	0.68	0.59	0.62	0.77	0.60	0.61	0.44	0.80	0.52	0.59	0.49	0.80	1.00	0.54	0.61	0.51	0.65	0.62	0.56	0.58	1.00	1.00	0.57	0.76	0.76	0.72	1.00	0.66	0.53	0.65	0.61	0.52	0.50	0.57	0.46	0.61	0.11	0.74
5921 (RASA1)	0.49	0.63	0.63	0.50	0.51	0.57	0.60	0.62	0.57	0.59	0.44	0.64	0.61	0.58	0.61	0.37	0.58	0.65	0.55	0.31	0.57	0.51	0.50	0.52	0.57	0.57	0.52	0.61	0.50	0.62	0.69	0.57	0.68	1.00	0.57	1.00	0.69	0.63	0.64	1.00	0.66	0.48	0.54	0.63	0.53	0.53	0.48	0.44	0.54	0.10	0.54
409 (ARRB2)	0.57	0.63	0.78	0.61	0.56	0.72	0.68	0.69	0.77	0.76	0.61	0.68	0.75	0.72	0.67	0.47	0.75	0.66	0.73	0.40	0.76	0.58	0.64	0.59	0.76	0.76	0.65	0.71	0.59	0.71	0.77	0.67	0.66	1.00	0.76	0.69	1.00	0.81	0.71	1.00	0.76	0.61	0.68	0.72	0.60	0.60	0.64	0.61	0.72	0.10	0.73
7414 (VCL)	0.58	0.63	0.79	0.62	0.54	0.68	0.65	0.65	0.76	0.75	0.52	0.63	0.68	0.75	0.61	0.47	0.75	0.65	0.72	0.40	0.76	0.58	0.63	0.57	0.76	0.76	0.60	0.66	0.59	0.68	0.70	0.60	0.65	1.00	0.76	0.63	0.81	1.00	0.76	1.00	0.69	0.59	0.67	0.65	0.60	0.59	0.64	0.61	0.66	0.10	0.73
1399 (CRKL)	0.56	0.59	0.71	0.55	0.60	0.65	0.67	0.64	0.70	0.75	0.52	0.65	0.66	0.71	0.64	0.47	0.80	0.61	0.61	0.38	0.70	0.54	0.61	0.52	0.70	0.72	0.56	0.68	0.54	0.66	0.64	0.58	0.62	1.00	0.72	0.64	0.71	0.76	1.00	1.00	0.70	0.57	0.65	0.66	0.63	0.60	0.67	0.51	0.61	0.10	0.83
1796 (DOK1)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.69	1.00	1.00	1.00	1.00	0.69	1.00	1.00	1.00	0.52	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.13	1.00
7525 (YES1)	0.68	0.55	0.70	0.80	0.65	0.63	0.84	0.65	0.67	0.67	0.49	0.67	0.67	0.63	0.83	0.41	0.65	0.58	0.61	0.35	0.65	0.77	0.79	0.71	0.65	0.66	0.86	0.97	0.74	0.66	0.62	0.79	0.59	1.00	0.66	0.66	0.76	0.69	0.70	1.00	1.00	0.78	0.84	0.92	0.88	0.59	0.71	0.71	0.93	0.38	0.63
5594 (MAPK1)	0.67	0.45	0.61	0.75	0.57	0.55	0.77	0.58	0.52	0.59	0.43	0.51	0.58	0.53	0.76	0.38	0.53	0.47	0.51	0.29	0.52	0.80	0.99	0.65	0.52	0.53	0.76	0.76	0.78	0.61	0.51	0.70	0.53	1.00	0.53	0.48	0.61	0.59	0.57	1.00	0.78	1.00	0.84	0.73	0.71	0.43	0.68	0.79	0.78	0.60	0.49
1445 (CSK)	0.66	0.56	0.66	0.79	0.62	0.64	0.80	0.62	0.69	0.73	0.49	0.58	0.65	0.61	0.81	0.43	0.63	0.60	0.60	0.35	0.63	0.79	0.85	0.67	0.63	0.65	0.81	0.83	0.73	0.64	0.57	0.73	0.58	1.00	0.65	0.54	0.68	0.67	0.65	1.00	0.84	0.84	1.00	0.82	0.77	0.54	0.72	0.73	0.86	0.41	0.60
2268 (FGR)	0.65	0.52	0.65	0.81	0.67	0.66	0.82	0.63	0.69	0.67	0.50	0.67	0.65	0.62	0.84	0.39	0.61	0.60	0.59	0.35	0.61	0.74	0.73	0.68	0.61	0.61	0.81	0.93	0.70	0.64	0.59	0.76	0.59	1.00	0.61	0.63	0.72	0.65	0.66	1.00	0.92	0.73	0.82	1.00	0.83	0.61	0.66	0.66	0.89	0.34	0.58
7535 (ZAP70)	0.62	0.62	0.58	0.73	0.56	0.53	0.76	0.57	0.51	0.55	0.40	0.56	0.57	0.53	0.75	0.33	0.53	0.59	0.48	0.29	0.51	0.72	0.71	0.63	0.51	0.52	0.75	0.90	0.67	0.58	0.51	0.69	0.51	1.00	0.52	0.53	0.60	0.60	0.63	1.00	0.88	0.71	0.77	0.83	1.00	0.47	0.61	0.76	0.84	0.45	0.49
5777 (PTPN6)	0.50	0.44	0.57	0.52	0.73	0.65	0.56	0.55	0.60	0.60	0.48	0.58	0.56	0.52	0.66	0.43	0.52	0.54	0.75	0.27	0.50	0.44	0.46	0.47	0.50	0.50	0.59	0.54	0.43	0.60	0.51	0.49	0.55	1.00	0.50	0.53	0.60	0.59	0.60	1.00	0.59	0.43	0.54	0.61	0.47	1.00	0.42	0.39	0.45	0.09	0.47
2549 (GAB1)	0.59	0.45	0.62	0.63	0.73	0.56	0.76	0.57	0.56	0.59	0.43	0.54	0.58	0.56	0.70	0.36	0.70	0.48	0.51	0.31	0.56	0.66	0.69	0.64	0.56	0.57	0.65	0.68	0.62	0.60	0.53	0.67	0.53	1.00	0.57	0.48	0.64	0.64	0.67	1.00	0.71	0.68	0.72	0.66	0.61	0.42	1.00	0.60	0.69	0.39	0.53
5567 (PRKACB)	0.61	0.56	0.53	0.66	0.52	0.50	0.73	0.54	0.46	0.50	0.36	0.49	0.54	0.49	0.69	0.30	0.48	0.54	0.53	0.26	0.46	0.72	0.78	0.58	0.46	0.46	0.69	0.68	0.69	0.56	0.53	0.63	0.53	1.00	0.46	0.44	0.61	0.61	0.51	1.00	0.71	0.79	0.73	0.66	0.76	0.39	0.60	1.00	0.68	0.56	0.44
640 (BLK)	0.65	0.48	0.67	0.79	0.56	0.59	0.81	0.64	0.61	0.63	0.48	0.60	0.63	0.60	0.79	0.38	0.62	0.52	0.54	0.33	0.61	0.78	0.79	0.71	0.61	0.61	0.86	0.96	0.74	0.63	0.58	0.78	0.54	1.00	0.61	0.54	0.72	0.66	0.61	1.00	0.93	0.78	0.86	0.89	0.84	0.45	0.69	0.68	1.00	0.52	0.57
5568 (PRKACG)	0.27	0.10	0.10	0.38	0.24	0.09	0.30	0.10	0.11	0.10	0.08	0.09	0.09	0.10	0.27	0.08	0.11	0.10	0.12	0.08	0.12	0.51	0.57	0.31	0.12	0.11	0.40	0.46	0.51	0.10	0.09	0.27	0.09	0.13	0.11	0.10	0.10	0.10	0.10	0.13	0.38	0.60	0.41	0.34	0.45	0.09	0.39	0.56	0.52	1.00	0.11
7145 (TNS1)	0.49	0.54	0.74	0.51	0.44	0.63	0.60	0.61	0.74	0.72	0.51	0.57	0.63	0.65	0.57	0.43	0.72	0.58	0.58	0.42	0.74	0.50	0.54	0.47	0.74	0.74	0.51	0.58	0.49	0.63	0.63	0.53	0.57	1.00	0.74	0.54	0.73	0.73	0.83	1.00	0.63	0.49	0.60	0.58	0.49	0.47	0.53	0.44	0.57	0.11	1.00

Association with High Altitude

Protein Official symbol	Source Organism	Tissue of Expression	Level of hypoxia	Altitude	Duration of experiment	Level of expression	Fold change	Experiment details	geographical location	ethnicity of the patients	Control group	Control (Fold change)	Reference (PMID)
CSK	Bird	Cardiac muscle	-	4000 m	Native	downregulated	-3.59	Sequencing	Central Asia	L. dichrous (Bird)	1	L. dichrous vs. Po. Palustris	31127049
CSK	Bird	Lungs	-	4000 m	Native	downregulated	-3.38	Sequencing	Central Asia	L. dichrous (Bird)	1	L. dichrous vs. Po. Palustris	31127049

Association with TF

TF	TF Entrez	Gene	Gene Entrez	Type	PMID	Database
MEF2C	4208	CSK	1445	proximal_filtered	22955619	TRANSFAC
BCL11A	53335	CSK	1445	proximal_filtered	22955619	TRANSFAC
MEF2A	4205	CSK	1445	proximal_filtered	22955619	TRANSFAC
SPI1	6688	CSK	1445	proximal_filtered	22955619	TRANSFAC
POU2F2	5452	CSK	1445	proximal_filtered	22955619	TRANSFAC
EBF1	1879	CSK	1445	proximal_filtered	22955619	TRANSFAC

Association with miRNA

miRTarBase ID	miRNA	Species (miRNA)	Protein Official Symbol	Human Entrez ID	Species (Target Gene)	Experiments	Support Type	References (PMID)
MIRT003960	hsa-miR-140-5p	Homo sapiens	CSK	1445	Homo sapiens	Microarray	Functional MTI (Weak)	17875710
MIRT030606	hsa-miR-24-3p	Homo sapiens	CSK	1445	Homo sapiens	Microarray	Functional MTI (Weak)	19748357
MIRT035928	hsa-miR-1180-3p	Homo sapiens	CSK	1445	Homo sapiens	CLASH	Functional MTI (Weak)	23622248
MIRT736232	hsa-miR-1233-5p	Homo sapiens	CSK	1445	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT738318	hsa-miR-1908-5p	Homo sapiens	CSK	1445	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT740242	hsa-miR-3148	Homo sapiens	CSK	1445	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT740345	hsa-miR-3151-5p	Homo sapiens	CSK	1445	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT740771	hsa-miR-3180-3p	Homo sapiens	CSK	1445	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT740811	hsa-miR-3180	Homo sapiens	CSK	1445	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT741055	hsa-miR-3194-5p	Homo sapiens	CSK	1445	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT741068	hsa-miR-3196	Homo sapiens	CSK	1445	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT743451	hsa-miR-4258	Homo sapiens	CSK	1445	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT745516	hsa-miR-4505	Homo sapiens	CSK	1445	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT747350	hsa-miR-4707-3p	Homo sapiens	CSK	1445	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT748217	hsa-miR-4747-3p	Homo sapiens	CSK	1445	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT750363	hsa-miR-541-3p	Homo sapiens	CSK	1445	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT751466	hsa-miR-5787	Homo sapiens	CSK	1445	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT753196	hsa-miR-6511b-5p	Homo sapiens	CSK	1445	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT753578	hsa-miR-663a	Homo sapiens	CSK	1445	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT753434	hsa-miR-654-5p	Homo sapiens	CSK	1445	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT753702	hsa-miR-671-5p	Homo sapiens	CSK	1445	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT755146	hsa-miR-6768-3p	Homo sapiens	CSK	1445	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT755179	hsa-miR-6769a-5p	Homo sapiens	CSK	1445	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT755225	hsa-miR-6769b-5p	Homo sapiens	CSK	1445	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT755939	hsa-miR-6787-5p	Homo sapiens	CSK	1445	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT756797	hsa-miR-6816-5p	Homo sapiens	CSK	1445	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT756683	hsa-miR-6811-5p	Homo sapiens	CSK	1445	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT759102	hsa-miR-7113-5p	Homo sapiens	CSK	1445	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT760547	hsa-miR-92a-2-5p	Homo sapiens	CSK	1445	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT760306	hsa-miR-873-5p	Homo sapiens	CSK	1445	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT760665	hsa-miR-92b-5p	Homo sapiens	CSK	1445	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT760878	hsa-miR-9500	Homo sapiens	CSK	1445	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625

Gene Ontology

ID	GO ID	GO Term	GO Type
1445	GO:0007417	central nervous system development	GOTERM_BP_DIRECT
1445	GO:0008285	negative regulation of cell proliferation	GOTERM_BP_DIRECT
1445	GO:0010989	negative regulation of low-density lipoprotein particle clearance	GOTERM_BP_DIRECT
1445	GO:0048709	oligodendrocyte differentiation	GOTERM_BP_DIRECT
1445	GO:0071375	cellular response to peptide hormone stimulus	GOTERM_BP_DIRECT
1445	GO:0005524	ATP binding	GOTERM_MF_DIRECT
1445	GO:0004713	protein serine/threonine/tyrosine kinase activity	GOTERM_MF_DIRECT
1445	GO:0045779	negative regulation of bone resorption	GOTERM_BP_DIRECT
1445	GO:0060368	regulation of Fc receptor mediated stimulatory signaling pathway	GOTERM_BP_DIRECT
1445	GO:0034236	apolipoprotein A-I receptor binding	GOTERM_MF_DIRECT
1445	GO:0031295	T cell costimulation	GOTERM_BP_DIRECT
1445	GO:0016301	kinase activity	GOTERM_MF_DIRECT
1445	GO:0033673	negative regulation of kinase activity	GOTERM_BP_DIRECT
1445	GO:0038083	peptidyl-tyrosine autophosphorylation	GOTERM_BP_DIRECT
1445	GO:0043406	positive regulation of MAP kinase activity	GOTERM_BP_DIRECT
1445	GO:0050765	negative regulation of phagocytosis	GOTERM_BP_DIRECT
1445	GO:0001817	regulation of cytokine production	GOTERM_BP_DIRECT
1445	GO:0006468	protein phosphorylation	GOTERM_BP_DIRECT
1445	GO:0030154	cell differentiation	GOTERM_BP_DIRECT
1445	GO:0042997	negative regulation of Golgi to plasma membrane protein transport	GOTERM_BP_DIRECT
1445	GO:0042802	identical protein binding	GOTERM_MF_DIRECT
1445	GO:0002250	adaptive immune response	GOTERM_BP_DIRECT
1445	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	GOTERM_BP_DIRECT
1445	GO:0019903	phosphatase binding	GOTERM_MF_DIRECT
1445	GO:0046872	metal ion binding	GOTERM_MF_DIRECT
1445	GO:0046777	protein autophosphorylation	GOTERM_BP_DIRECT
1445	GO:0007420	brain development	GOTERM_BP_DIRECT
1445	GO:0016477	cell migration	GOTERM_BP_DIRECT
1445	GO:0050852	T cell receptor signaling pathway	GOTERM_BP_DIRECT
1445	GO:0005515	protein binding	GOTERM_MF_DIRECT
1445	GO:0070064	thrombospondin receptor activity	GOTERM_MF_DIRECT
1445	GO:0032715	negative regulation of interleukin-6 production	GOTERM_BP_DIRECT
1445	GO:0042127	regulation of cell proliferation	GOTERM_BP_DIRECT
1445	GO:0004715	transmembrane receptor protein tyrosine kinase activity	GOTERM_MF_DIRECT
1445	GO:0008022	microtubule binding	GOTERM_MF_DIRECT
1445	GO:0045087	innate immune response	GOTERM_BP_DIRECT
1445	GO:0034332	adherens junction organization	GOTERM_BP_DIRECT
1445	GO:0070373	negative regulation of ERK1 and ERK2 cascade	GOTERM_BP_DIRECT
1445	GO:0007173	epidermal growth factor receptor signaling pathway	GOTERM_BP_DIRECT
1445	GO:0005102	receptor binding	GOTERM_MF_DIRECT
1445	GO:0005737	cytoplasm	GOTERM_CC_DIRECT
1445	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	GOTERM_CC_DIRECT
1445	GO:0005911	cell-cell junction	GOTERM_CC_DIRECT
1445	GO:0070062	extracellular exosome	GOTERM_CC_DIRECT
1445	GO:0045121	membrane raft	GOTERM_CC_DIRECT
1445	GO:0005829	cytosol	GOTERM_CC_DIRECT
1445	GO:0005886	plasma membrane	GOTERM_CC_DIRECT

Pathways

Human Entrez ID	KEGG ID	KEGG Term
1445	hsa05120	Epithelial cell signaling in Helicobacter pylori infection

Association with Disease

Protein Official Symbol	Human Entrez ID	Disease Name	Disease Id	Disease Semantic Type	Semantic score	DSI	DPI	Disease Type
CSK	1445	Lupus Erythematosus, Systemic	C0024141	Disease or Syndrome	0.32	0.633	0.621	disease
CSK	1445	Hyperalgesia	C0020429	Sign or Symptom	0.3	0.633	0.621	phenotype
CSK	1445	Libman-Sacks Disease	C0242380	Disease or Syndrome	0.3	0.633	0.621	disease
CSK	1445	Hyperalgesia, Thermal	C0751214	Sign or Symptom	0.3	0.633	0.621	phenotype
CSK	1445	Hyperalgesia, Primary	C0751211	Sign or Symptom	0.3	0.633	0.621	phenotype
CSK	1445	Mechanical Allodynia	C2936719	Sign or Symptom	0.3	0.633	0.621	phenotype
CSK	1445	Hyperalgesia, Secondary	C0751212	Sign or Symptom	0.3	0.633	0.621	phenotype
CSK	1445	Tactile Allodynia	C0751213	Sign or Symptom	0.3	0.633	0.621	phenotype
CSK	1445	Allodynia	C0458247	Finding	0.3	0.633	0.621	phenotype

Association with Drug

Protein Official Symbol	Human Entrez ID	drug_claim_primary_name	drug_name	drug_chembl_id	interaction_types
CSK	1445	APATINIB	None	None	inhibitor
CSK	1445	NG-25	None	None	inhibitor
CSK	1445	PP1	CHEMBL306380	CHEMBL306380	inhibitor