ALTITUDEOMICSDB

Paxillin

AltitudeomicsDB

Protein Official symbol	PXN
Aliases	PXN
Chromosomal Location	12
Length	591
Uniprot ID	P49023
EC number	None
Protein family Information(Pfam)	PF00412;
PDB id	1KKY;1KL0;1OW6;1OW7;1OW8;2K2R;2O9V;2VZD;2VZG;2VZI;3GM1;3PY7;3RQE;3RQF;3RQG;3U3F;4EDN;4R32;4XGZ;4XH2;5UWH;6IUI;6U4M;6U4N;
InterPro ID	IPR017305;IPR001781;
dbSNP	rs4767884

Protein Protein Interaction

Download Tab separated file

AltitudeomicsDB

Protein 1	Protein 2	Combine Score
VEGFA	KDR	0.998
PXN	VCL	0.997
PARVB	ILK	0.997
EGFR	EGF	0.997
PTK2	PXN	0.997
MYLK	MYL9	0.995
ILK	PARVA	0.995
SRC	PXN	0.994
VEGFA	EGF	0.993
BCAR1	PXN	0.993
BCAR1	CRK	0.992
BCAR1	SRC	0.992
PTK2B	PXN	0.992
CTTN	SRC	0.991
CRK	DOCK1	0.991
CDC42	PAK1	0.991
ILK	PXN	0.991
BCAR1	PTK2	0.99
SRC	EGF	0.99
VEGFA	FN1	0.988
FN1	EGF	0.988
VEGFA	SRC	0.987
BCAR1	PTK2B	0.987
SRC	VCL	0.987
PTPN11	MAPK3	0.987
CDC42	SRC	0.986
ITGB3	ITGAV	0.986
TLN1	VCL	0.986
CDC42	ARHGEF7	0.984
PTPN11	EGFR	0.984
RHOA	MYL9	0.984
PTK2	VCL	0.984
PTPN11	MAPK1	0.983
BCAR1	DOCK1	0.983
CRK	PXN	0.983
GIT1	PXN	0.983
CDC42	PTK2	0.983
FN1	VCL	0.983
FN1	PXN	0.983
PTPN11	PXN	0.982
ITGB1	FN1	0.982
CTTN	PTK2	0.982
ACTN1	VCL	0.981
RHOA	VCL	0.981
GIT1	ARHGEF7	0.981
CDC42	PXN	0.981
ITGB1	ITGAV	0.981
BCAR1	FYN	0.98
RHOA	PXN	0.98
GIT2	PXN	0.98
VEGFA	EGFR	0.979
RHOA	MAPK1	0.979
SRC	EZR	0.979
BCAR1	VCL	0.979
NCK1	CDC42	0.979
SRC	CRK	0.977
BCAR1	CRKL	0.977
RHOA	SRC	0.977
VEGFA	RHOA	0.977
TLN1	PXN	0.976
ARHGEF7	GIT2	0.976
CTTN	PXN	0.976
CDC42	CTTN	0.976
SRC	FN1	0.975
FN1	PTK2	0.975
RHOA	ARF6	0.975
ARHGEF7	PAK1	0.975
ILK	ITGB1	0.975
PARVA	PXN	0.974
SRC	DOCK1	0.974
ACTN4	VCL	0.974
PXN	MAPK1	0.974
ITGB1	VCL	0.974
RHOA	PTK2	0.973
ITGB1	ITGA9	0.973
RHOA	MAPK3	0.972
CDC42	DOCK1	0.971
VEGFA	CDC42	0.971
RHOA	EZR	0.97
FN1	ITGAV	0.97
FN1	MAPK3	0.97
CDC42	EGFR	0.97
ILK	NCK2	0.969
CTTN	PAK1	0.969
PTK6	PXN	0.969
PTK2B	PTPN11	0.968
PTK2	PTPN11	0.968
ITGB3	TLN1	0.968
RAC1	PXN	0.968
GIT1	ARF6	0.968
CDC42	FN1	0.968
BCAR1	FN1	0.967
PXN	MAPK3	0.967
FYN	PXN	0.967
RHOA	PTPN11	0.967
BRK1	NCK1	0.966
NCK1	GIT1	0.966
CDC42	EGF	0.966
DOCK1	PXN	0.966
ILK	MYL9	0.966
RAC1	PAK1	0.965
NCK1	PTK2	0.965
FN1	MAPK1	0.965
ARF6	EGF	0.965
PTK2	CRK	0.965
RHOA	EGFR	0.965
FYN	CRK	0.965
CDC42	GIT1	0.965
PXN	CSK	0.964
HCK	PXN	0.964
CDC42	FYN	0.964
RHOA	EGF	0.964
CDC42	NCK2	0.964
RHOA	PAK1	0.964
LYN	BCAR1	0.964
SRC	TNS1	0.964
RAC1	ARF6	0.963
ACTN1	TLN1	0.963
ITGB3	ILK	0.963
ITGB1	TLN1	0.963
VEGFA	PTK2	0.963
CDC42	CRK	0.963
RHOA	FYN	0.963
PTK6	BCAR1	0.963
PTK2	TLN1	0.962
RAC1	DOCK1	0.962
ITGB3	FN1	0.962
GIT2	PTK2	0.962
CDC42	GIT2	0.962
SORBS3	VCL	0.962
NCK1	PAK1	0.961
CDC42	MYLK	0.961
CDC42	MYL9	0.96
ITGB1	PXN	0.96
CTTN	FYN	0.96
EZR	PXN	0.96
PXN	TNS1	0.96
ARF6	PXN	0.96
SRC	RAC1	0.959
RHOA	PTK2B	0.959
BCAR1	CDC42	0.959
PXN	EGF	0.959
EGFR	PXN	0.959
CTTN	EGFR	0.959
MAPK3	VCL	0.958
RHOA	DOCK1	0.958
ITGB1	PTK2	0.958
FYN	CRKL	0.958
PTPN11	EGF	0.957
ITGB3	KDR	0.957
RHOA	BCAR1	0.957
LYN	PTPN11	0.957
TLN1	ACTN4	0.957
VCL	TNS1	0.957
CRKL	DOCK1	0.957
MYLK	PXN	0.957
MYLK	VCL	0.957
BCAR1	CSK	0.956
NCK1	BCAR1	0.956
CRKL	PXN	0.956
RHOA	TNS1	0.956
PXN	SORBS3	0.956
RHOA	ARHGEF7	0.955
ITGB3	VCL	0.955
CTTN	RAC1	0.955
BCAR1	PTPN11	0.955
NCK1	PXN	0.955
ITGB1	EGF	0.955
VEGFA	ITGB1	0.955
PTK2B	CRK	0.954
FYN	EGF	0.954
FYN	VCL	0.954
GIT1	PAK1	0.954
PARVA	TNS1	0.953
EZR	PTK2	0.953
RHOA	CRK	0.953
ILK	TNS1	0.953
CTTN	EGF	0.952
ITGB1	KDR	0.952
BCAR1	TNS1	0.952
PTK2	TNS1	0.952
PXN	ITGA9	0.952
BRK1	CDC42	0.951
VEGFA	PXN	0.951
NCK1	RAC1	0.951
LYN	CRKL	0.951
ARHGEF7	PXN	0.951
PAK1	PXN	0.95
RHOA	KDR	0.95
SRC	ARF6	0.95
ILK	ARHGEF7	0.95
ACTN1	PXN	0.95
EGF	CSK	0.95
CDC42	ITGB1	0.95
PTK2	DOCK1	0.95
FN1	TLN1	0.95
PTK2	ACTN4	0.949
MAPK1	VCL	0.949
RAC1	CRK	0.949
TLN1	ITGAV	0.949
ITGB1	ACTN1	0.949
RHOA	TLN1	0.948
PXN	ACTN4	0.948
LYN	PXN	0.948
RAC1	PTK2	0.948
ITGB1	SRC	0.947
CDC42	KDR	0.947
PTPN11	KDR	0.947
GIT1	NCK2	0.947
SRC	TLN1	0.947
BCAR1	TLN1	0.947
BRK1	PXN	0.947
RHOA	ACTN4	0.946
MYL9	PXN	0.946
ITGB1	EGFR	0.946
YES1	CDC42	0.946
ITGB3	SRC	0.946
MYL9	VCL	0.946
ILK	ITGAV	0.946
BCAR1	RAC1	0.946
PXN	KDR	0.946
RAC1	FN1	0.946
RAC1	MAPK3	0.945
FN1	CRK	0.945
YES1	PXN	0.945
BCAR1	ITGB1	0.944
ITGB3	PTK2	0.944
VEGFA	PTPN11	0.944
EZR	RAC1	0.944
ARHGEF7	SRC	0.944
GIT2	PAK1	0.944
ITGB3	PXN	0.944
SRC	PTPN11	0.943
CAPN2	PXN	0.943
VEGFA	ITGAV	0.943
ARF6	EGFR	0.943
YES1	VCL	0.943
CSK	VCL	0.943
RHOA	CSK	0.943
EZR	ACTN4	0.943
RAC1	FYN	0.943
GIT1	RAC1	0.943
PXN	ITGAV	0.942
PARVB	PXN	0.942
PXN	NCK2	0.942
ACTN1	FN1	0.942
RHOA	ITGB1	0.941
PTK6	EGF	0.941
VEGFA	FYN	0.941
ITGB1	ACTN4	0.941
NCK1	GIT2	0.941
RAC1	GIT2	0.941
LYN	EGF	0.941
RAC1	EGF	0.941
RAC1	EGFR	0.941
SRC	MAPK3	0.941
HCK	PTPN11	0.941
SRC	MAPK1	0.94
SRC	ITGAV	0.94
YES1	BCAR1	0.94
RAC1	MAPK1	0.94
YES1	CRK	0.94
PTK2	ITGAV	0.94
LYN	CRK	0.939
YES1	RHOA	0.939
FN1	ITGA9	0.939
VEGFA	BCAR1	0.939
YES1	EGF	0.939
ITGB3	RHOA	0.939
VEGFA	ITGB3	0.939
TLN1	CAPN2	0.939
CAPN2	MAPK3	0.939
SRC	GIT2	0.939
VEGFA	PTK2B	0.939
MYLK	RAC1	0.939
FN1	CSK	0.939
HCK	CRK	0.939
SRC	CAPN2	0.938
CRKL	PTK2	0.937
PTK2B	CRKL	0.937
FYN	PTPN11	0.937
EGFR	MAPK3	0.937
LYN	RHOA	0.937
HCK	EGF	0.937
ITGB3	CDC42	0.937
PTPN11	CSK	0.937
ILK	ACTN1	0.937
EGFR	MAPK1	0.937
LYN	MAPK3	0.937
VEGFA	CSK	0.937
ARHGEF7	RAC1	0.936
FN1	ARF6	0.936
PTK2B	RAC1	0.935
FN1	ACTN4	0.935
FYN	DOCK1	0.935
NCK1	DOCK1	0.935
BCAR1	KDR	0.934
TLN1	TNS1	0.934
KDR	ITGAV	0.934
CRK	ARF6	0.934
HCK	BCAR1	0.934
BRK1	RAC1	0.933
FYN	MAPK1	0.933
RHOA	ACTN1	0.933
CAPN2	MAPK1	0.933
NCK1	FYN	0.933
PTK2	MAPK3	0.932
RAC1	NCK2	0.932
CRKL	VCL	0.932
MAPK3	CSK	0.932
SRC	PAK1	0.932
SRC	EGFR	0.931
PAK1	NCK2	0.931
SRC	ACTN4	0.931
ARF6	MAPK3	0.931
ILK	RAC1	0.931
ITGB3	PTK2B	0.93
PTPN11	CRK	0.93
BRK1	DOCK1	0.93
PTK2	CAPN2	0.93
SRC	CRKL	0.93
SRC	KDR	0.93
ACTN1	EZR	0.93
LYN	MAPK1	0.929
BCAR1	ITGAV	0.929
ACTN1	SRC	0.929
GIT1	FN1	0.929
NCK1	SRC	0.929
PTK2	MAPK1	0.929
RHOA	CDC42	0.928
MYLK	MAPK1	0.928
CSK	MAPK1	0.928
PTK2	NCK2	0.928
YES1	EGFR	0.928
CTTN	GIT2	0.928
HCK	LYN	0.928
ITGB3	MAPK3	0.928
PTK6	CRK	0.928
PTK2B	SRC	0.928
ARHGEF7	EGFR	0.927
CRKL	PTPN11	0.926
EZR	TLN1	0.926
MAPK3	ITGAV	0.926
PTK2	KDR	0.926
CDC42	ITGAV	0.926
BCAR1	ACTN4	0.926
SRC	PTK2	0.926
ILK	GIT2	0.926
TLN1	SORBS3	0.925
NCK1	ARF6	0.925
PTK2B	ITGB1	0.925
LYN	RAC1	0.925
CSK	TNS1	0.925
VEGFA	NCK1	0.925
CRK	KDR	0.925
PTK2B	FYN	0.925
ITGB1	EZR	0.925
BCAR1	ACTN1	0.924
ITGB3	MAPK1	0.924
ITGB1	TNS1	0.924
MYLK	TLN1	0.924
SRC	NCK2	0.924
ITGB1	FYN	0.924
FYN	EGFR	0.924
RHOA	ITGAV	0.923
BCAR1	NCK2	0.923
VEGFA	ACTN4	0.923
PTK6	EGFR	0.923
LYN	EGFR	0.923
ARHGEF7	EGF	0.923
NCK1	KDR	0.923
CRK	PAK1	0.923
ARHGEF7	FYN	0.923
RAC1	CRKL	0.923
PTK2B	EGFR	0.923
HCK	EGFR	0.922
ACTN1	PTK2	0.922
ITGB3	BCAR1	0.922
ITGAV	MAPK1	0.922
PARVB	ACTN1	0.921
RAC1	MYL9	0.921
MYLK	PTK2	0.921
ITGB1	CTTN	0.921
FYN	PAK1	0.921
ARF6	MAPK1	0.921
SRC	ITGA9	0.92
MYLK	MAPK3	0.92
SRC	CSK	0.92
FYN	PTK2	0.92
FYN	TLN1	0.92
YES1	PTPN11	0.92
CRKL	ARF6	0.92
ARHGEF7	PTK2	0.92
RAC1	TLN1	0.92
FYN	NCK2	0.919
EGF	ACTN4	0.919
CTTN	ARHGEF7	0.919
GIT1	FYN	0.919
RAC1	KDR	0.919
ACTN1	EGF	0.919
TLN1	CRK	0.919
HCK	PTK2B	0.919
YES1	RAC1	0.918
CRKL	TLN1	0.918
ITGB1	CAPN2	0.918
NCK1	ARHGEF7	0.918
MYLK	SORBS3	0.918
MYLK	PAK1	0.918
TLN1	MYL9	0.918
YES1	PTK2	0.918
FYN	CSK	0.917
CRK	ITGAV	0.917
YES1	CRKL	0.917
FYN	ITGAV	0.917
FYN	CAPN2	0.917
ITGB1	ARF6	0.917
HCK	CSK	0.917
DOCK1	PAK1	0.917
CRKL	TNS1	0.917
HCK	CRKL	0.917
MYL9	PAK1	0.917
EGFR	CSK	0.916
YES1	MAPK1	0.916
ITGB1	MYLK	0.916
LYN	CSK	0.916
LYN	PTK2B	0.916
RAC1	ACTN4	0.916
TLN1	MAPK1	0.916
ITGB1	RAC1	0.916
TLN1	MAPK3	0.916
CRKL	CSK	0.916
YES1	DOCK1	0.916
PTK2	CSK	0.916
ITGB3	CRK	0.915
VEGFA	ITGA9	0.915
FYN	KDR	0.915
ITGB1	PAK1	0.915
LYN	PTK2	0.915
YES1	PTK2B	0.915
DOCK1	KDR	0.913
KDR	NCK2	0.913
TLN1	CSK	0.913
RHOA	RAC1	0.913
PTK2B	ITGAV	0.913
YES1	ITGAV	0.913
ITGB3	RAC1	0.913
ITGB3	CSK	0.913
ITGB1	ARHGEF7	0.913
PTK2B	KDR	0.912
ITGB1	CRKL	0.912
PTK2	PAK1	0.912
HCK	PTK2	0.911
MYL9	SORBS3	0.911
ACTN4	TNS1	0.91
PTK6	RHOA	0.91
ACTN1	RAC1	0.91
VEGFA	ACTN1	0.91
CRKL	ACTN4	0.91
YES1	CSK	0.91
ACTN1	FYN	0.909
ITGB1	CSK	0.908
ARHGEF7	NCK2	0.908
RAC1	ITGAV	0.908
VEGFA	NCK2	0.908
ACTN1	ACTN4	0.908
ACTN1	CRKL	0.908
ACTN1	TNS1	0.908
YES1	NCK1	0.908
ITGB3	ITGB1	0.908
YES1	PAK1	0.907
PTK2B	PTK2	0.907
KDR	CSK	0.907
BRK1	PTK2	0.906
CDC42	RAC1	0.906
CRKL	CRK	0.906
GIT2	NCK2	0.906
YES1	ACTN1	0.905
HCK	FYN	0.905
YES1	NCK2	0.905
LYN	FYN	0.905
YES1	ARHGEF7	0.905
ACTN4	CSK	0.905
LYN	SRC	0.905
HCK	SRC	0.905
ITGB3	ITGA9	0.905
ITGB3	ARF6	0.904
ITGB1	GIT2	0.904
ITGB3	GIT1	0.904
GIT2	FYN	0.904
ARF6	ITGAV	0.903
ACTN1	CSK	0.903
PARVB	PARVA	0.903
SRC	FYN	0.903
YES1	HCK	0.902
CRK	EGFR	0.902
YES1	LYN	0.902
BRK1	CRK	0.902
MAPK3	MAPK1	0.902
NCK1	NCK2	0.902
YES1	CAPN2	0.901
YES1	FYN	0.901
YES1	SRC	0.901
BRK1	MAPK1	0.901
BRK1	MAPK3	0.901
BRK1	BCAR1	0.9
PTK6	DOCK1	0.9
YES1	GIT2	0.9
BRK1	KDR	0.9
ARF6	ITGA9	0.9

Gene Ontology Semantic Similarity

Download Tab separated file

#	3791 (KDR)	7414 (VCL)	3611 (ILK)	1950 (EGF)	5829 (PXN)	10398 (MYL9)	55742 (PARVA)	1398 (CRK)	6714 (SRC)	1793 (DOCK1)	5058 (PAK1)	5747 (PTK2)	2335 (FN1)	2185 (PTK2B)	5595 (MAPK3)	3685 (ITGAV)	8874 (ARHGEF7)	1956 (EGFR)	5594 (MAPK1)	2534 (FYN)	7430 (EZR)	998 (CDC42)	1399 (CRKL)	387 (RHOA)	9815 (GIT2)	2017 (CTTN)	382 (ARF6)	3688 (ITGB1)	8440 (NCK2)	5781 (PTPN11)	7094 (TLN1)	4690 (NCK1)	28964 (GIT1)	1445 (CSK)	9564 (BCAR1)	7145 (TNS1)	4638 (MYLK)	5879 (RAC1)	81 (ACTN4)	10174 (SORBS3)	87 (ACTN1)	3690 (ITGB3)	824 (CAPN2)	4067 (LYN)	3055 (HCK)	7422 (VEGFA)	29780 (PARVB)	5753 (PTK6)	55845 (BRK1)	7525 (YES1)
3791 (KDR)	1.00	0.60	0.68	0.72	0.59	0.26	0.57	0.59	0.76	0.49	0.71	0.70	0.63	0.76	0.71	0.70	0.50	0.75	0.71	0.70	0.64	0.63	0.59	0.50	1.00	0.58	0.50	0.70	0.55	0.56	0.61	0.57	1.00	0.76	0.55	0.53	0.71	0.63	0.55	0.53	0.57	0.71	0.51	0.72	0.76	0.59	0.56	0.80	0.54	0.76
7414 (VCL)	0.60	1.00	0.70	0.57	0.79	0.26	0.89	0.72	0.65	0.67	0.63	0.62	0.68	0.58	0.63	0.66	0.66	0.58	0.59	0.60	0.78	0.60	0.76	0.65	1.00	0.84	0.66	0.75	0.72	0.54	0.75	0.71	1.00	0.67	0.76	0.73	0.65	0.64	0.64	0.72	0.63	0.68	0.68	0.60	0.66	0.65	0.84	0.68	0.73	0.69
3611 (ILK)	0.68	0.70	1.00	0.61	0.69	0.26	0.69	0.72	0.75	0.53	0.82	0.79	0.62	0.75	0.84	0.64	0.65	0.61	0.84	0.67	0.70	0.72	0.64	0.64	1.00	0.71	0.53	0.64	0.63	0.60	0.62	0.64	1.00	0.83	0.83	0.62	0.88	0.77	0.52	0.61	0.53	0.63	0.55	0.72	0.79	0.60	0.68	0.81	0.63	0.80
1950 (EGF)	0.72	0.57	0.61	1.00	0.55	0.26	0.52	0.56	0.74	0.60	0.63	0.74	0.55	0.69	0.64	0.59	0.60	0.74	0.65	0.76	0.59	0.56	0.52	0.46	1.00	0.53	0.45	0.60	0.51	0.56	0.51	0.58	1.00	0.67	0.49	0.47	0.64	0.58	0.47	0.48	0.47	0.61	0.46	0.67	0.70	0.61	0.50	0.71	0.49	0.71
5829 (PXN)	0.59	0.79	0.69	0.55	1.00	0.26	0.78	0.72	0.62	0.66	0.61	0.62	0.68	0.55	0.65	0.65	0.65	0.54	0.61	0.60	0.72	0.58	0.71	0.64	1.00	0.79	0.64	0.68	0.72	0.52	0.75	0.68	1.00	0.66	0.77	0.74	0.63	0.63	0.58	0.80	0.65	0.67	0.67	0.60	0.66	0.64	0.79	0.69	0.73	0.70
10398 (MYL9)	0.26	0.26	0.26	0.26	0.26	1.00	0.26	0.26	0.26	0.26	0.26	0.26	0.59	0.26	0.26	0.26	0.26	0.26	0.26	0.26	0.26	0.26	0.26	0.26	0.26	0.26	0.26	0.26	0.40	0.26	0.59	0.40	0.26	0.26	0.26	0.26	0.26	0.26	0.26	0.59	0.26	0.26	0.26	0.26	0.26	0.34	0.26	0.26	0.26	0.26
55742 (PARVA)	0.57	0.89	0.69	0.52	0.78	0.26	1.00	0.72	0.63	0.64	0.59	0.59	0.66	0.52	0.59	0.64	0.63	0.52	0.54	0.56	0.80	0.56	0.78	0.62	1.00	0.92	0.62	0.76	0.72	0.49	0.77	0.71	1.00	0.65	0.80	0.75	0.61	0.60	0.61	0.73	0.61	0.66	0.66	0.56	0.63	0.63	0.94	0.66	0.74	0.67
1398 (CRK)	0.59	0.72	0.72	0.56	0.72	0.26	0.72	1.00	0.71	0.64	0.62	0.65	0.67	0.57	0.61	0.66	0.69	0.52	0.58	0.62	0.73	0.62	0.81	0.67	1.00	0.73	0.63	0.67	0.82	0.67	0.68	0.75	1.00	0.67	0.77	0.69	0.63	0.65	0.58	0.69	0.61	0.66	0.64	0.63	0.72	0.64	0.72	0.67	0.69	0.74
6714 (SRC)	0.76	0.65	0.75	0.74	0.62	0.26	0.63	0.71	1.00	0.56	0.76	0.80	0.68	0.77	0.77	0.63	0.58	0.73	0.77	0.81	0.68	0.71	0.67	0.58	1.00	0.64	0.57	0.66	0.64	0.72	0.65	0.67	1.00	0.80	0.61	0.60	0.77	0.73	0.62	0.58	0.61	0.67	0.58	0.83	0.81	0.64	0.60	0.81	0.59	0.84
1793 (DOCK1)	0.49	0.67	0.53	0.60	0.66	0.26	0.64	0.64	0.56	1.00	0.47	0.62	0.59	0.41	0.49	0.59	0.94	0.54	0.45	0.62	0.66	0.49	0.61	0.50	1.00	0.66	0.49	0.62	0.60	0.41	0.59	0.61	1.00	0.54	0.61	0.56	0.45	0.51	0.50	0.57	0.50	0.61	0.51	0.47	0.51	0.59	0.63	0.54	0.58	0.57
5058 (PAK1)	0.71	0.63	0.82	0.63	0.61	0.26	0.59	0.62	0.76	0.47	1.00	0.73	0.63	0.76	0.82	0.58	0.49	0.63	0.82	0.68	0.65	0.66	0.58	0.49	1.00	0.61	0.48	0.63	0.57	0.56	0.57	0.57	1.00	0.78	0.56	0.53	0.86	0.70	0.51	0.54	0.52	0.62	0.51	0.73	0.79	0.57	0.58	0.81	0.69	0.80
5747 (PTK2)	0.70	0.62	0.79	0.74	0.62	0.26	0.59	0.65	0.80	0.62	0.73	1.00	0.57	0.75	0.75	0.59	0.70	0.74	0.75	0.78	0.67	0.69	0.55	0.56	1.00	0.56	0.48	0.60	0.54	0.61	0.54	0.58	1.00	0.79	0.62	0.51	0.76	0.72	0.53	0.52	0.51	0.59	0.51	0.74	0.78	0.56	0.59	0.79	0.52	0.80
2335 (FN1)	0.63	0.68	0.62	0.55	0.68	0.59	0.66	0.67	0.68	0.59	0.63	0.57	1.00	0.56	0.61	0.68	0.60	0.55	0.58	0.71	0.70	0.61	0.66	0.61	1.00	0.67	0.61	0.72	0.64	0.55	0.72	0.66	1.00	0.65	0.66	0.63	0.58	0.63	0.62	0.67	0.64	0.72	0.60	0.59	0.62	0.72	0.65	0.66	0.64	0.67
2185 (PTK2B)	0.76	0.58	0.75	0.69	0.55	0.26	0.52	0.57	0.77	0.41	0.76	0.75	0.56	1.00	0.75	0.58	0.43	0.66	0.75	0.70	0.60	0.63	0.52	0.44	1.00	0.53	0.42	0.59	0.51	0.52	0.51	0.54	1.00	0.81	0.48	0.45	0.79	0.66	0.46	0.47	0.46	0.59	0.44	0.76	0.82	0.55	0.49	0.84	0.48	0.82
5595 (MAPK3)	0.71	0.63	0.84	0.64	0.65	0.26	0.59	0.61	0.77	0.49	0.82	0.75	0.61	0.75	1.00	0.58	0.50	0.67	0.99	0.70	0.65	0.71	0.61	0.51	1.00	0.61	0.50	0.61	0.57	0.58	0.56	0.58	1.00	0.85	0.57	0.54	0.85	0.73	0.51	0.54	0.51	0.63	0.53	0.76	0.77	0.60	0.58	0.82	0.55	0.79
3685 (ITGAV)	0.70	0.66	0.64	0.59	0.65	0.26	0.64	0.66	0.63	0.59	0.58	0.59	0.68	0.58	0.58	1.00	0.62	0.58	0.56	0.58	0.67	0.59	0.63	0.62	1.00	0.65	0.59	0.79	0.63	0.57	0.67	0.63	1.00	0.62	0.67	0.62	0.58	0.62	0.60	0.62	0.62	0.85	0.59	0.57	0.60	0.65	0.64	0.61	0.62	0.63
8874 (ARHGEF7)	0.50	0.66	0.65	0.60	0.65	0.26	0.63	0.69	0.58	0.94	0.49	0.70	0.60	0.43	0.50	0.62	1.00	0.55	0.46	0.62	0.68	0.56	0.61	0.60	1.00	0.65	0.50	0.62	0.60	0.48	0.59	0.63	1.00	0.60	0.74	0.57	0.47	0.59	0.51	0.57	0.51	0.61	0.52	0.48	0.52	0.59	0.62	0.55	0.58	0.59
1956 (EGFR)	0.75	0.58	0.61	0.74	0.54	0.26	0.52	0.52	0.73	0.54	0.63	0.74	0.55	0.66	0.67	0.58	0.55	1.00	0.67	0.73	0.64	0.60	0.56	0.46	1.00	0.52	0.46	0.65	0.48	0.55	0.51	0.54	1.00	0.66	0.48	0.49	0.62	0.62	0.55	0.47	0.52	0.62	0.46	0.63	0.64	0.56	0.49	0.67	0.50	0.68
5594 (MAPK1)	0.71	0.59	0.84	0.65	0.61	0.26	0.54	0.58	0.77	0.45	0.82	0.75	0.58	0.75	0.99	0.56	0.46	0.67	1.00	0.70	0.63	0.72	0.57	0.47	1.00	0.56	0.46	0.58	0.53	0.57	0.53	0.55	1.00	0.84	0.52	0.49	0.84	0.74	0.49	0.50	0.49	0.61	0.49	0.76	0.76	0.58	0.53	0.81	0.51	0.78
2534 (FYN)	0.70	0.60	0.67	0.76	0.60	0.26	0.56	0.62	0.81	0.62	0.68	0.78	0.71	0.70	0.70	0.58	0.62	0.73	0.70	1.00	0.63	0.64	0.58	0.52	1.00	0.57	0.52	0.59	0.56	0.60	0.56	0.60	1.00	0.73	0.56	0.53	0.69	0.65	0.53	0.54	0.53	0.63	0.54	0.76	0.77	0.64	0.56	0.80	0.55	0.79
7430 (EZR)	0.64	0.78	0.70	0.59	0.72	0.26	0.80	0.73	0.68	0.66	0.65	0.67	0.70	0.60	0.65	0.67	0.68	0.64	0.63	0.63	1.00	0.66	0.80	0.68	1.00	0.76	0.66	0.75	0.69	0.60	0.73	0.70	1.00	0.73	0.74	0.77	0.65	0.67	0.75	0.69	0.73	0.71	0.68	0.61	0.65	0.66	0.77	0.68	0.69	0.68
998 (CDC42)	0.63	0.60	0.72	0.56	0.58	0.26	0.56	0.62	0.71	0.49	0.66	0.69	0.61	0.63	0.71	0.59	0.56	0.60	0.72	0.64	0.66	1.00	0.59	0.78	1.00	0.57	0.78	0.58	0.55	0.57	0.55	0.58	1.00	0.71	0.61	0.53	0.67	0.88	0.53	0.53	0.51	0.61	0.53	0.64	0.65	0.59	0.55	0.69	0.54	0.69
1399 (CRKL)	0.59	0.76	0.64	0.52	0.71	0.26	0.78	0.81	0.67	0.61	0.58	0.55	0.66	0.52	0.61	0.63	0.61	0.56	0.57	0.58	0.80	0.59	1.00	0.61	1.00	0.80	0.61	0.69	0.83	0.60	0.71	0.74	1.00	0.65	0.70	0.83	0.59	0.60	0.67	0.66	0.66	0.66	0.61	0.56	0.68	0.64	0.72	0.66	0.68	0.70
387 (RHOA)	0.50	0.65	0.64	0.46	0.64	0.26	0.62	0.67	0.58	0.50	0.49	0.56	0.61	0.44	0.51	0.62	0.60	0.46	0.47	0.52	0.68	0.78	0.61	1.00	1.00	0.63	0.89	0.61	0.59	0.51	0.58	0.61	1.00	0.60	0.71	0.58	0.48	0.85	0.54	0.57	0.52	0.61	0.57	0.49	0.52	0.59	0.61	0.55	0.58	0.58
9815 (GIT2)	1.00	1.00	1.00	1.00	1.00	0.26	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00
2017 (CTTN)	0.58	0.84	0.71	0.53	0.79	0.26	0.92	0.73	0.64	0.66	0.61	0.56	0.67	0.53	0.61	0.65	0.65	0.52	0.56	0.57	0.76	0.57	0.80	0.63	1.00	1.00	0.64	0.73	0.73	0.50	0.78	0.71	1.00	0.66	0.82	0.77	0.63	0.61	0.57	0.74	0.60	0.67	0.66	0.57	0.65	0.64	0.84	0.67	0.76	0.68
382 (ARF6)	0.50	0.66	0.53	0.45	0.64	0.26	0.62	0.63	0.57	0.49	0.48	0.48	0.61	0.42	0.50	0.59	0.50	0.46	0.46	0.52	0.66	0.78	0.61	0.89	1.00	0.64	1.00	0.61	0.59	0.44	0.58	0.59	1.00	0.55	0.60	0.57	0.46	0.86	0.53	0.56	0.51	0.61	0.54	0.48	0.52	0.59	0.61	0.54	0.57	0.59
3688 (ITGB1)	0.70	0.75	0.64	0.60	0.68	0.26	0.76	0.67	0.66	0.62	0.63	0.60	0.72	0.59	0.61	0.79	0.62	0.65	0.58	0.59	0.75	0.58	0.69	0.61	1.00	0.73	0.61	1.00	0.66	0.56	0.73	0.67	1.00	0.63	0.67	0.65	0.61	0.61	0.66	0.65	0.65	0.81	0.63	0.59	0.62	0.67	0.72	0.64	0.71	0.65
8440 (NCK2)	0.55	0.72	0.63	0.51	0.72	0.40	0.72	0.82	0.64	0.60	0.57	0.54	0.64	0.51	0.57	0.63	0.60	0.48	0.53	0.56	0.69	0.55	0.83	0.59	1.00	0.73	0.59	0.66	1.00	0.60	0.67	0.80	1.00	0.62	0.71	0.67	0.57	0.58	0.55	0.68	0.57	0.64	0.62	0.55	0.68	0.62	0.72	0.62	0.67	0.70
5781 (PTPN11)	0.56	0.54	0.60	0.56	0.52	0.26	0.49	0.67	0.72	0.41	0.56	0.61	0.55	0.52	0.58	0.57	0.48	0.55	0.57	0.60	0.60	0.57	0.60	0.51	1.00	0.50	0.44	0.56	0.60	1.00	0.51	0.59	1.00	0.62	0.53	0.44	0.55	0.59	0.48	0.45	0.48	0.57	0.48	0.57	0.62	0.53	0.47	0.58	0.46	0.65
7094 (TLN1)	0.61	0.75	0.62	0.51	0.75	0.59	0.77	0.68	0.65	0.59	0.57	0.54	0.72	0.51	0.56	0.67	0.59	0.51	0.53	0.56	0.73	0.55	0.71	0.58	1.00	0.78	0.58	0.73	0.67	0.51	1.00	0.68	1.00	0.61	0.68	0.65	0.57	0.57	0.60	0.88	0.67	0.68	0.61	0.55	0.60	0.62	0.69	0.62	0.65	0.63
4690 (NCK1)	0.57	0.71	0.64	0.58	0.68	0.40	0.71	0.75	0.67	0.61	0.57	0.58	0.66	0.54	0.58	0.63	0.63	0.54	0.55	0.60	0.70	0.58	0.74	0.61	1.00	0.71	0.59	0.67	0.80	0.59	0.68	1.00	1.00	0.62	0.68	0.63	0.58	0.60	0.57	0.64	0.58	0.65	0.60	0.59	0.63	0.65	0.66	0.64	0.64	0.65
28964 (GIT1)	1.00	1.00	1.00	1.00	1.00	0.26	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00
1445 (CSK)	0.76	0.67	0.83	0.67	0.66	0.26	0.65	0.67	0.80	0.54	0.78	0.79	0.65	0.81	0.85	0.62	0.60	0.66	0.84	0.73	0.73	0.71	0.65	0.60	1.00	0.66	0.55	0.63	0.62	0.62	0.61	0.62	1.00	1.00	0.69	0.60	0.82	0.72	0.53	0.60	0.55	0.64	0.58	0.81	0.83	0.62	0.64	0.89	0.61	0.84
9564 (BCAR1)	0.55	0.76	0.83	0.49	0.77	0.26	0.80	0.77	0.61	0.61	0.56	0.62	0.66	0.48	0.57	0.67	0.74	0.48	0.52	0.56	0.74	0.61	0.70	0.71	1.00	0.82	0.60	0.67	0.71	0.53	0.68	0.68	1.00	0.69	1.00	0.74	0.57	0.66	0.54	0.71	0.56	0.65	0.62	0.54	0.61	0.62	0.82	0.64	0.73	0.67
7145 (TNS1)	0.53	0.73	0.62	0.47	0.74	0.26	0.75	0.69	0.60	0.56	0.53	0.51	0.63	0.45	0.54	0.62	0.57	0.49	0.49	0.53	0.77	0.53	0.83	0.58	1.00	0.77	0.57	0.65	0.67	0.44	0.65	0.63	1.00	0.60	0.74	1.00	0.53	0.57	0.65	0.66	0.64	0.63	0.58	0.51	0.58	0.61	0.76	0.61	0.68	0.63
4638 (MYLK)	0.71	0.65	0.88	0.64	0.63	0.26	0.61	0.63	0.77	0.45	0.86	0.76	0.58	0.79	0.85	0.58	0.47	0.62	0.84	0.69	0.65	0.67	0.59	0.48	1.00	0.63	0.46	0.61	0.57	0.55	0.57	0.58	1.00	0.82	0.57	0.53	1.00	0.71	0.49	0.54	0.49	0.60	0.49	0.76	0.84	0.58	0.59	0.86	0.55	0.83
5879 (RAC1)	0.63	0.64	0.77	0.58	0.63	0.26	0.60	0.65	0.73	0.51	0.70	0.72	0.63	0.66	0.73	0.62	0.59	0.62	0.74	0.65	0.67	0.88	0.60	0.85	1.00	0.61	0.86	0.61	0.58	0.59	0.57	0.60	1.00	0.72	0.66	0.57	0.71	1.00	0.54	0.56	0.52	0.63	0.55	0.65	0.67	0.59	0.59	0.69	0.58	0.74
81 (ACTN4)	0.55	0.64	0.52	0.47	0.58	0.26	0.61	0.58	0.62	0.50	0.51	0.53	0.62	0.46	0.51	0.60	0.51	0.55	0.49	0.53	0.75	0.53	0.67	0.54	1.00	0.57	0.53	0.66	0.55	0.48	0.60	0.57	1.00	0.53	0.54	0.65	0.49	0.54	1.00	0.53	0.80	0.62	0.53	0.52	0.53	0.59	0.61	0.55	0.55	0.58
10174 (SORBS3)	0.53	0.72	0.61	0.48	0.80	0.59	0.73	0.69	0.58	0.57	0.54	0.52	0.67	0.47	0.54	0.62	0.57	0.47	0.50	0.54	0.69	0.53	0.66	0.57	1.00	0.74	0.56	0.65	0.68	0.45	0.88	0.64	1.00	0.60	0.71	0.66	0.54	0.56	0.53	1.00	0.60	0.63	0.60	0.52	0.58	0.61	0.73	0.60	0.67	0.63
87 (ACTN1)	0.57	0.63	0.53	0.47	0.65	0.26	0.61	0.61	0.61	0.50	0.52	0.51	0.64	0.46	0.51	0.62	0.51	0.52	0.49	0.53	0.73	0.51	0.66	0.52	1.00	0.60	0.51	0.65	0.57	0.48	0.67	0.58	1.00	0.55	0.56	0.64	0.49	0.52	0.80	0.60	1.00	0.64	0.54	0.52	0.53	0.60	0.60	0.55	0.55	0.59
3690 (ITGB3)	0.71	0.68	0.63	0.61	0.67	0.26	0.66	0.66	0.67	0.61	0.62	0.59	0.72	0.59	0.63	0.85	0.61	0.62	0.61	0.63	0.71	0.61	0.66	0.61	1.00	0.67	0.61	0.81	0.64	0.57	0.68	0.65	1.00	0.64	0.65	0.63	0.60	0.63	0.62	0.63	0.64	1.00	0.61	0.60	0.63	0.76	0.65	0.65	0.64	0.66
824 (CAPN2)	0.51	0.68	0.55	0.46	0.67	0.26	0.66	0.64	0.58	0.51	0.51	0.51	0.60	0.44	0.53	0.59	0.52	0.46	0.49	0.54	0.68	0.53	0.61	0.57	1.00	0.66	0.54	0.63	0.62	0.48	0.61	0.60	1.00	0.58	0.62	0.58	0.49	0.55	0.53	0.60	0.54	0.61	1.00	0.51	0.54	0.59	0.66	0.56	0.59	0.59
4067 (LYN)	0.72	0.60	0.72	0.67	0.60	0.26	0.56	0.63	0.83	0.47	0.73	0.74	0.59	0.76	0.76	0.57	0.48	0.63	0.76	0.76	0.61	0.64	0.56	0.49	1.00	0.57	0.48	0.59	0.55	0.57	0.55	0.59	1.00	0.81	0.54	0.51	0.76	0.65	0.52	0.52	0.52	0.60	0.51	1.00	0.84	0.61	0.54	0.86	0.53	0.86
3055 (HCK)	0.76	0.66	0.79	0.70	0.66	0.26	0.63	0.72	0.81	0.51	0.79	0.78	0.62	0.82	0.77	0.60	0.52	0.64	0.76	0.77	0.65	0.65	0.68	0.52	1.00	0.65	0.52	0.62	0.68	0.62	0.60	0.63	1.00	0.83	0.61	0.58	0.84	0.67	0.53	0.58	0.53	0.63	0.54	0.84	1.00	0.64	0.62	0.94	0.59	0.97
7422 (VEGFA)	0.59	0.65	0.60	0.61	0.64	0.34	0.63	0.64	0.64	0.59	0.57	0.56	0.72	0.55	0.60	0.65	0.59	0.56	0.58	0.64	0.66	0.59	0.64	0.59	1.00	0.64	0.59	0.67	0.62	0.53	0.62	0.65	1.00	0.62	0.62	0.61	0.58	0.59	0.59	0.61	0.60	0.76	0.59	0.61	0.64	1.00	0.63	0.67	0.62	0.65
29780 (PARVB)	0.56	0.84	0.68	0.50	0.79	0.26	0.94	0.72	0.60	0.63	0.58	0.59	0.65	0.49	0.58	0.64	0.62	0.49	0.53	0.56	0.77	0.55	0.72	0.61	1.00	0.84	0.61	0.72	0.72	0.47	0.69	0.66	1.00	0.64	0.82	0.76	0.59	0.59	0.61	0.73	0.60	0.65	0.66	0.54	0.62	0.63	1.00	0.65	0.75	0.67
5753 (PTK6)	0.80	0.68	0.81	0.71	0.69	0.26	0.66	0.67	0.81	0.54	0.81	0.79	0.66	0.84	0.82	0.61	0.55	0.67	0.81	0.80	0.68	0.69	0.66	0.55	1.00	0.67	0.54	0.64	0.62	0.58	0.62	0.64	1.00	0.89	0.64	0.61	0.86	0.69	0.55	0.60	0.55	0.65	0.56	0.86	0.94	0.67	0.65	1.00	0.62	0.92
55845 (BRK1)	0.54	0.73	0.63	0.49	0.73	0.26	0.74	0.69	0.59	0.58	0.69	0.52	0.64	0.48	0.55	0.62	0.58	0.50	0.51	0.55	0.69	0.54	0.68	0.58	1.00	0.76	0.57	0.71	0.67	0.46	0.65	0.64	1.00	0.61	0.73	0.68	0.55	0.58	0.55	0.67	0.55	0.64	0.59	0.53	0.59	0.62	0.75	0.62	1.00	0.64
7525 (YES1)	0.76	0.69	0.80	0.71	0.70	0.26	0.67	0.74	0.84	0.57	0.80	0.80	0.67	0.82	0.79	0.63	0.59	0.68	0.78	0.79	0.68	0.69	0.70	0.58	1.00	0.68	0.59	0.65	0.70	0.65	0.63	0.65	1.00	0.84	0.67	0.63	0.83	0.74	0.58	0.63	0.59	0.66	0.59	0.86	0.97	0.65	0.67	0.92	0.64	1.00

Association with High Altitude

Protein Official symbol	Source Organism	Tissue of Expression	Level of hypoxia	Altitude	Duration of experiment	Level of expression	Fold change	Experiment details	geographical location	ethnicity of the patients	Control group	Control (Fold change)	Reference (PMID)
PXN	Human	Blood	-	3250 m	4 day	upregulated	2.25	Microarray	Himalayas	Indians	1	Sea level healthy individuals	24465776
PXN	Human	Blood	-	3250 m	4 day	upregulated	2.25	Microarray	Himalayas	Indians	1	Sea level healthy individuals	24465776
PXN	Human	Blood	-	3250 m	4 day	upregulated	2.25	Microarray	Himalayas	Indians	1	Sea level healthy individuals	24465776

Association with TF

TF	TF Entrez	Gene	Gene Entrez	Type	PMID	Database
GATA2	2624	PXN	5829	proximal_filtered	22955619	TRANSFAC
RAD21	5885	PXN	5829	proximal_filtered	22955619	TRANSFAC

Association with miRNA

miRTarBase ID	miRNA	Species (miRNA)	Protein Official Symbol	Human Entrez ID	Species (Target Gene)	Experiments	Support Type	References (PMID)
MIRT007346	hsa-miR-137	Homo sapiens	PXN	5829	Homo sapiens	Luciferase reporter assay//qRT-PCR//Western blot	Functional MTI	23275153
MIRT018650	hsa-miR-335-5p	Homo sapiens	PXN	5829	Homo sapiens	Microarray	Functional MTI (Weak)	18185580
MIRT023030	hsa-miR-124-3p	Homo sapiens	PXN	5829	Homo sapiens	Microarray	Functional MTI (Weak)	18668037
MIRT046850	hsa-miR-221-3p	Homo sapiens	PXN	5829	Homo sapiens	CLASH	Functional MTI (Weak)	23622248
MIRT049136	hsa-miR-92a-3p	Homo sapiens	PXN	5829	Homo sapiens	CLASH	Functional MTI (Weak)	23622248
MIRT732117	hsa-miR-212-3p	Homo sapiens	PXN	5829	Homo sapiens	Luciferase reporter assay//qRT-PCR//Western blot	Functional MTI	26693054
MIRT732799	hsa-miR-27b-5p	Homo sapiens	PXN	5829	Homo sapiens	Luciferase reporter assay//Western blot	Functional MTI	26473412
MIRT734440	hsa-miR-145-5p	Homo sapiens	PXN	5829	Homo sapiens	Luciferase reporter assay//qRT-PCR//Western blot	Functional MTI	25973017
MIRT736599	hsa-miR-1255b-5p	Homo sapiens	PXN	5829	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT736576	hsa-miR-1255a	Homo sapiens	PXN	5829	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT737549	hsa-miR-139-3p	Homo sapiens	PXN	5829	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT739989	hsa-miR-3123	Homo sapiens	PXN	5829	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT740562	hsa-miR-3165	Homo sapiens	PXN	5829	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT741756	hsa-miR-3621	Homo sapiens	PXN	5829	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT741931	hsa-miR-3656	Homo sapiens	PXN	5829	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT742525	hsa-miR-3691-5p	Homo sapiens	PXN	5829	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT742856	hsa-miR-3913-3p	Homo sapiens	PXN	5829	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT742885	hsa-miR-3915	Homo sapiens	PXN	5829	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT743049	hsa-miR-3928-3p	Homo sapiens	PXN	5829	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT747979	hsa-miR-4734	Homo sapiens	PXN	5829	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT748350	hsa-miR-4753-5p	Homo sapiens	PXN	5829	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT748974	hsa-miR-4796-3p	Homo sapiens	PXN	5829	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT751237	hsa-miR-5693	Homo sapiens	PXN	5829	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT751717	hsa-miR-6077	Homo sapiens	PXN	5829	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT754443	hsa-miR-6744-5p	Homo sapiens	PXN	5829	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT754897	hsa-miR-6759-3p	Homo sapiens	PXN	5829	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625
MIRT755694	hsa-miR-6782-3p	Homo sapiens	PXN	5829	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	26701625

Gene Ontology

ID	GO ID	GO Term	GO Type
5829	GO:0007155	cell adhesion	GOTERM_BP_DIRECT
5829	GO:0007165	signal transduction	GOTERM_BP_DIRECT
5829	GO:0008270	zinc ion binding	GOTERM_MF_DIRECT
5829	GO:0005925	focal adhesion	GOTERM_CC_DIRECT
5829	GO:0005654	nucleoplasm	GOTERM_CC_DIRECT
5829	GO:0007179	transforming growth factor beta receptor signaling pathway	GOTERM_BP_DIRECT
5829	GO:0034614	cellular response to reactive oxygen species	GOTERM_BP_DIRECT
5829	GO:0005875	microtubule associated complex	GOTERM_CC_DIRECT
5829	GO:0060396	growth hormone receptor signaling pathway	GOTERM_BP_DIRECT
5829	GO:0005737	cytoplasm	GOTERM_CC_DIRECT
5829	GO:0005829	cytosol	GOTERM_CC_DIRECT
5829	GO:0005886	plasma membrane	GOTERM_CC_DIRECT
5829	GO:0006936	muscle contraction	GOTERM_BP_DIRECT
5829	GO:0008013	chemokine activity	GOTERM_MF_DIRECT
5829	GO:0030027	lamellipodium	GOTERM_CC_DIRECT
5829	GO:0007172	signal complex assembly	GOTERM_BP_DIRECT
5829	GO:0048010	vascular endothelial growth factor receptor signaling pathway	GOTERM_BP_DIRECT
5829	GO:0005856	cytoskeleton	GOTERM_CC_DIRECT
5829	GO:0005178	integrin binding	GOTERM_MF_DIRECT
5829	GO:0001725	stress fiber	GOTERM_CC_DIRECT
5829	GO:0007160	cell-matrix adhesion	GOTERM_BP_DIRECT
5829	GO:0007173	epidermal growth factor receptor signaling pathway	GOTERM_BP_DIRECT
5829	GO:0005515	protein binding	GOTERM_MF_DIRECT
5829	GO:0019901	protein kinase binding	GOTERM_MF_DIRECT
5829	GO:0005938	cell cortex	GOTERM_CC_DIRECT
5829	GO:0017166	semaphorin receptor activity	GOTERM_MF_DIRECT

Pathways

Human Entrez ID	KEGG ID	KEGG Term
5829	hsa04062	Chemokine signaling pathway
5829	hsa04370	VEGF signaling pathway
5829	hsa04510	Focal adhesion
5829	hsa04670	Leukocyte transendothelial migration
5829	hsa04810	Regulation of actin cytoskeleton
5829	hsa05100	Bacterial invasion of epithelial cells
5829	hsa05205	Proteoglycans in cancer
5829	hsa05203	Viral carcinogenesis

Association with Disease

Protein Official Symbol	Human Entrez ID	Disease Name	Disease Id	Disease Semantic Type	Semantic score	DSI	DPI	Disease Type
PXN	5829	Non-Small Cell Lung Carcinoma	C0007131	Neoplastic Process	0.34	0.604	0.517	disease
PXN	5829	Neoplastic Cell Transformation	C0007621	Neoplastic Process	0.3	0.604	0.517	phenotype
PXN	5829	Neoplasm Metastasis	C0027627	Neoplastic Process	0.4	0.604	0.517	phenotype
PXN	5829	Melanoma, Experimental	C0025205	Experimental Model of Disease; Neoplastic Process	0.3	0.604	0.517	disease
PXN	5829	Melanoma, B16	C0004565	Experimental Model of Disease; Neoplastic Process	0.3	0.604	0.517	disease
PXN	5829	Melanoma, Cloudman S91	C0009075	Experimental Model of Disease; Neoplastic Process	0.3	0.604	0.517	disease
PXN	5829	Melanoma, Harding-Passey	C0018598	Experimental Model of Disease; Neoplastic Process	0.3	0.604	0.517	disease

Association with Drug

Protein Official Symbol	Human Entrez ID	drug_claim_primary_name	drug_name	drug_chembl_id	interaction_types
PXN	5829	ANTISENSE OLIGONUCLEOTIDES	None	None	None
PXN	5829	H2O2	HYDROGEN PEROXIDE	CHEMBL71595	None
PXN	5829	LOVASTATIN	LOVASTATIN	CHEMBL503	None