ALTITUDEOMICSDB

β-synuclein

AltitudeomicsDB

Protein Official symbol	SNCB
Aliases	SNCB
Chromosomal Location	5
Length	134
Uniprot ID	Q16143
EC number	None
Protein family Information(Pfam)	PF01387;
PDB id	None
InterPro ID	IPR001058;IPR002461;
dbSNP	None

Protein Protein Interaction

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AltitudeomicsDB

Protein 1	Protein 2	Combine Score
CPLX1	SNAP25	0.998
SNAP25	RAB3A	0.991
SLC17A7	SLC32A1	0.988
SYN1	SNAP25	0.986
SYN1	RAB3A	0.981
SNAP25	SLC32A1	0.973
SNAP25	SLC17A7	0.972
CPLX1	RAB3A	0.97
CPLX2	SNAP25	0.966
CCK	NTSR2	0.963
CAMK2A	MAPT	0.9620000000000001
CPLX1	SYN1	0.9620000000000001
RAB3A	SLC17A7	0.9570000000000001
CPLX1	SLC17A7	0.9520000000000001
RAB3A	SLC32A1	0.95
MAPT	APP	0.9490000000000001
CPLX1	SLC32A1	0.9470000000000001
HRH3	HTR5A	0.9470000000000001
RAB3C	RAB3A	0.9159999999999999
RAB14	RAB8B	0.915
CCK	APP	0.914
RAB8B	RAB3A	0.9129999999999999
RAB8B	RAB3C	0.912
SYP	SNAP25	0.91
RAB14	RAB3A	0.909
RAB14	SNAP25	0.909
HRH3	APP	0.907
RAB14	RAB3C	0.907
NTSR2	APP	0.9059999999999999
HTR5A	APP	0.904
MTF1	SNCB	0.9
CPLX2	CPLX1	0.898
SYN1	SYP	0.88
SYP	SLC17A7	0.856
SYN1	SLC17A7	0.83
SYN1	SLC32A1	0.813
FAM171B	SLC1A2	0.7979999999999999
OPALIN	HTR5A	0.792
ATP2B3	SLC8A2	0.7859999999999999
SYP	RAB3A	0.7859999999999999
HPCA	KCNC1	0.785
SYP	SLC32A1	0.7829999999999999
SLC1A2	SLC17A7	0.775
RAB3C	SNAP25	0.7709999999999999
APP	SYP	0.7659999999999999
SYNPR	SNAP25	0.758
MTF1	MT3	0.755
SNCB	RAB3A	0.727
UNC5A	SNCB	0.698
STMN2	SNAP25	0.687
SNCB	TMEM263	0.687
OPALIN	KCNJ9	0.684
TSACC	SNCB	0.684
MAPT	SYP	0.682
SLC1A2	SLC32A1	0.6779999999999999
KCNJ9	HTR5A	0.675
SNCB	SNAP25	0.67
SNCB	SNCAIP	0.664
SCRT1	KCNC1	0.662
SNCB	SYP	0.6579999999999999
OPALIN	KCNC1	0.657
SNCB	CPLX1	0.657
KCNJ9	KCNC1	0.655
CCK	SLC32A1	0.655
CPLX2	SYP	0.654
KCNC1	SLC32A1	0.654
MAPT	SNCB	0.654
OPALIN	NTSR2	0.65
RAB8B	SNCB	0.647
CAMK2A	CPLX2	0.647
CPLX2	SNCB	0.647
UCHL1	SYP	0.6459999999999999
CPLX2	SLC32A1	0.6459999999999999
MAPT	SLC1A2	0.6459999999999999
APP	UCHL1	0.645
CPLX2	RAB3A	0.644
SLC1A2	SNAP25	0.639
CAMK2A	SYN1	0.635
SYNC	SNCB	0.634
STMN2	ELAVL4	0.632
SYNC	RAB8B	0.631
SNCB	SLC32A1	0.63
STMN2	ACTL6B	0.63
SYNC	RAB3A	0.626
PIAS2	SNCB	0.626
SNCB	SLC17A7	0.626
PIAS2	RAB8B	0.622
SYN1	RAB3C	0.62
PIAS2	SYNC	0.62
SLC1A2	SYP	0.615
CAMK2A	KCNC1	0.613
KCNJ9	SNCB	0.611
SYNPR	SNCB	0.611
SNCB	SLC1A2	0.61
CCK	HTR5A	0.608
SYNPR	SLC17A7	0.603
MAPT	SNAP25	0.599
ELAVL4	SNAP25	0.599
HPCA	ATP2B3	0.598
SCRT1	CDK5R2	0.597
GABRD	CPLX1	0.596
SNCB	MT3	0.596
CPLX2	KCNC1	0.593
SNCB	NEUROD6	0.5920000000000001
OPALIN	SLC32A1	0.591
MAPT	SYN1	0.589
SNCB	SYN1	0.588
GABRD	SLC32A1	0.5870000000000001
NTSR2	HTR5A	0.586
CCK	SNCB	0.585
ELAVL4	SNCB	0.584
SNCB	ACTL6B	0.584
SNCAIP	RAB3A	0.583
HPCA	SNCB	0.583
SCRT1	SLC8A2	0.581
SYN1	APP	0.581
ELAVL4	MAPT	0.579
GABRD	NTSR2	0.578
SYNPR	HTR5A	0.578
SNCB	UCHL1	0.5770000000000001
GABRD	SNCB	0.5770000000000001
KCNJ4	KCNC1	0.575
SNCB	RAB3C	0.575
KCTD16	SNCB	0.574
KCNC1	SNAP25	0.573
SCRT1	SLC32A1	0.5720000000000001
CCK	SLC17A7	0.57
CA10	HTR5A	0.569
HRH3	SNCB	0.569
SNCB	APP	0.5670000000000001
SNCB	NTSR2	0.5670000000000001
STMN2	SNCB	0.5660000000000001
CPLX1	SYP	0.565
CDK5R2	SNAP25	0.565
GABRD	KCNC1	0.562
STMN2	SYN1	0.562
ATP2B3	SNAP25	0.562
SYNPR	CA10	0.562
FAM163B	HTR5A	0.561
SYNPR	NTSR2	0.561
SCRT1	KCNJ9	0.561
SYNC	SNCAIP	0.56
CPLX2	SYN1	0.5589999999999999
CCK	KCNJ9	0.557
SNCB	CDK5R2	0.557
CA10	MT3	0.555
SNCB	FAM171B	0.555
CPLX2	CDK5R2	0.555
KCNJ9	MT3	0.5529999999999999
MAPT	UCHL1	0.5529999999999999
HPCA	SYN1	0.5529999999999999
SYNPR	RAB3C	0.5529999999999999
CAMK2A	CDK5R2	0.5529999999999999
SNCB	HTR5A	0.552
OPALIN	FAM163B	0.551
SYNPR	KCNJ9	0.551
KCNJ9	HRH3	0.551
RAB14	SNCB	0.55
KCNJ9	SLC32A1	0.55
CAMK2A	SNCB	0.5489999999999999
OPALIN	MT3	0.5479999999999999
CAMK2A	HTR5A	0.547
SYNPR	OPALIN	0.547
CA10	KCNJ9	0.547
HTR5A	SLC8A2	0.544
NEUROD6	HTR5A	0.544
SYN1	ACTL6B	0.5429999999999999
KCNJ9	NTSR2	0.5429999999999999
CA10	ATP2B3	0.5429999999999999
KCNJ9	FAM163B	0.542
SYNPR	SLC32A1	0.542
FAM163B	SNCB	0.542
GABRD	HTR5A	0.541
CA10	VSTM2B	0.541
KCNJ9	ATP2B3	0.541
HTR5A	ATP2B3	0.541
SNCB	KCNJ4	0.54
GABRD	OPALIN	0.54
STMN2	SYP	0.539
HPCA	SNAP25	0.539
SCRT1	SLC17A7	0.5379999999999999
SYN1	SLC1A2	0.5379999999999999
NTSR2	MT3	0.5379999999999999
SCRT1	NEUROD6	0.537
SEPT4	SNCB	0.537
OPALIN	SNCB	0.536
HTR5A	SLC17A7	0.536
SNCB	KCNC1	0.536
HTR5A	SLC32A1	0.536
GABRD	KCNJ9	0.536
SCRT1	SNCB	0.535
STMN2	SLC1A2	0.535
STMN2	SYNPR	0.535
HTR5A	MT3	0.535
HRH3	NTSR2	0.535
KCNJ9	VSTM2B	0.535
STMN2	SLC32A1	0.535
SCRT1	HTR5A	0.535
GABRD	FAM163B	0.534
FAM163B	SLC32A1	0.534
SCRT1	FAM163B	0.534
CCK	OPALIN	0.534
SNCB	ATP2B3	0.534
HPCA	KCNJ9	0.534
OPALIN	VSTM2B	0.5329999999999999
VSTM2B	SNCB	0.5329999999999999
SYNPR	FAM163B	0.5329999999999999
HPCA	HTR5A	0.5329999999999999
SNCB	SLC8A2	0.5329999999999999
SCRT1	ATP2B3	0.5329999999999999
FAM163B	NTSR2	0.5329999999999999
FAM163B	ATP2B3	0.5329999999999999
VSTM2B	ATP2B3	0.5329999999999999
GABRD	VSTM2B	0.532
SYNPR	CCK	0.532
KCNC1	ATP2B3	0.532
CA10	SNCB	0.532
SCRT1	HPCA	0.532
SCRT1	VSTM2B	0.532
VSTM2B	HTR5A	0.532
FAM163B	VSTM2B	0.532
SYNPR	ATP2B3	0.531
OPALIN	ATP2B3	0.531
SCRT1	OPALIN	0.531
HPCA	FAM163B	0.531
SCRT1	HRH3	0.531
HPCA	OPALIN	0.531
CCK	FAM163B	0.531
KCTD8	SNCB	0.531
STMN2	CA10	0.531
GABRD	HPCA	0.531
SCRT1	CPLX2	0.53
GABRD	ATP2B3	0.53
FAM163B	HRH3	0.53
SCRT1	CA10	0.53
SYNPR	MT3	0.53
VSTM2B	NTSR2	0.53
FAM163B	KCNJ4	0.53
SCRT1	NTSR2	0.53
APP	SNAP25	0.529
KCNJ9	CPLX2	0.529
ATP2B3	SLC32A1	0.528
SYNPR	GABRD	0.528
CAMK2A	SLC17A7	0.528
SYNPR	SYN1	0.527
CAMK2A	SNAP25	0.526
CA10	OPALIN	0.526
GABRD	SLC17A7	0.525
CA10	FAM163B	0.522
SEPT4	OPALIN	0.522
GABRD	HRH3	0.521
HTR5A	KCNC1	0.521
OPALIN	SNAP25	0.52
RAB3C	SNCAIP	0.52
KCNJ9	SLC8A2	0.517
CAMK2A	SYP	0.517
KCNJ9	SNAP25	0.517
SCRT1	SNAP25	0.516
RAB3C	SYP	0.515
SYNPR	SLC1A2	0.515
NEUROD6	SLC17A7	0.515
UCHL1	SNCAIP	0.514
SYN1	SLC8A2	0.514
CA10	SNAP25	0.512
STMN2	NEUROD6	0.512
NEUROD6	ATP2B3	0.511
SYNPR	HPCA	0.511
KCNJ9	SYN1	0.51
CAMK2A	HPCA	0.51
NEUROD6	SLC32A1	0.51
CAMK2A	OPALIN	0.509
HRH3	VSTM2B	0.509
CCK	SNAP25	0.509
SCRT1	CCK	0.509
CAMK2A	SLC32A1	0.509
CA10	SLC32A1	0.509
CA10	NEUROD6	0.508
GABRD	MT3	0.507
VSTM2B	SLC32A1	0.506
ELAVL4	NEUROD6	0.506
KCNJ9	NEUROD6	0.505
VSTM2B	MT3	0.505
GABRD	KCNJ4	0.505
SCRT1	SYNPR	0.505
CDK5R2	HTR5A	0.504
SYNPR	VSTM2B	0.504
CPLX2	SLC17A7	0.501
CDK5R2	SLC32A1	0.5
FAM163B	MT3	0.499
ATP2B3	MT3	0.499
GABRD	CPLX2	0.498
FAM163B	SLC8A2	0.498
HPCA	SLC8A2	0.4970000000000001
CA10	KCNC1	0.496
CPLX2	ACTL6B	0.496
SCRT1	MT3	0.494
CA10	GABRD	0.494
HPCA	MT3	0.493
ELAVL4	SLC32A1	0.493
KCNJ4	ATP2B3	0.492
HPCA	NTSR2	0.492
CCK	GABRD	0.492
HRH3	SLC8A2	0.491
HTR5A	SNAP25	0.491
GABRD	NEUROD6	0.491
CAMK2A	KCNJ9	0.49
PIAS2	RAB3A	0.489
RAB3C	SLC32A1	0.489
KCNJ9	ACTL6B	0.489
CAMK2A	NTSR2	0.488
NTSR2	ATP2B3	0.488
ELAVL4	SYP	0.487
CPLX1	RAB3C	0.487
CA10	CCK	0.486
CA10	HPCA	0.485
CCK	SYP	0.484
SCRT1	SYN1	0.484
CPLX2	HTR5A	0.483
SYNPR	CAMK2A	0.483
SYN1	HTR5A	0.483
FAM171B	SNCAIP	0.483
CPLX2	ELAVL4	0.483
SYN1	KCNC1	0.482
VSTM2B	KCNC1	0.482
CAMK2A	ACTL6B	0.48
HPCA	ACTL6B	0.479
SEPT4	SNCAIP	0.478
CCK	HPCA	0.478
SNAP25	MT3	0.477
APP	SLC1A2	0.477
CPLX2	FAM163B	0.476
CA10	NTSR2	0.475
HPCA	SLC32A1	0.475
HRH3	SLC32A1	0.475
STMN2	CPLX2	0.475
KCNC1	SLC8A2	0.474
NEUROD6	SNAP25	0.474
CCK	SYN1	0.472
CDK5R2	KCNC1	0.472
CA10	SLC8A2	0.472
STMN2	MAPT	0.47
HRH3	ATP2B3	0.469
FAM163B	KCNC1	0.469
CCK	KCNC1	0.468
GABRD	SLC8A2	0.467
SCRT1	CPLX1	0.467
CAMK2A	SLC8A2	0.467
NTSR2	SLC32A1	0.465
GABRD	SNAP25	0.465
CAMK2A	ATP2B3	0.464
KCNJ4	HTR5A	0.464
CAMK2A	RAB3A	0.463
RAB3C	SLC17A7	0.463
CCK	MT3	0.462
KCNJ9	KCNJ4	0.461
CPLX2	SLC8A2	0.461
HPCA	VSTM2B	0.46
FAM163B	SYN1	0.46
CPLX1	CDK5R2	0.46
SLC32A1	MT3	0.459
MAPT	SLC17A7	0.458
KCNJ9	SLC17A7	0.457
SYN1	ATP2B3	0.456
KCNJ9	CDK5R2	0.455
HPCA	CDK5R2	0.454
SNAP25	ACTL6B	0.453
CA10	ACTL6B	0.453
GABRD	ACTL6B	0.453
KCNC1	SLC17A7	0.452
VSTM2B	KCNJ4	0.452
GABRD	UNC5A	0.452
CDK5R2	SYN1	0.451
SCRT1	ACTL6B	0.45
FAM163B	CDK5R2	0.449
ATP2B3	ACTL6B	0.448
CDK5R2	SLC8A2	0.448
SYNPR	NEUROD6	0.448
OPALIN	SLC8A2	0.447
RAB8B	SNCAIP	0.447
SYNPR	KCNC1	0.446
SYNPR	RAB3A	0.446
SCRT1	GABRD	0.445
SYNPR	ACTL6B	0.444
SYNPR	SLC8A2	0.444
UNC5A	CDK5R2	0.4429999999999999
ELAVL4	KCNC1	0.4429999999999999
OPALIN	NEUROD6	0.442
KCTD16	KCNJ9	0.441
VSTM2B	SNAP25	0.441
KCNC1	ACTL6B	0.441
ELAVL4	ACTL6B	0.441
CDK5R2	SYP	0.44
OPALIN	SLC17A7	0.44
CA10	CPLX2	0.44
SYNPR	CPLX2	0.439
HPCA	SYP	0.4379999999999999
KCNJ4	SLC32A1	0.4379999999999999
SCRT1	KCNJ4	0.436
NTSR2	SNAP25	0.436
CDK5R2	ATP2B3	0.435
SYNPR	HRH3	0.435
CPLX2	ATP2B3	0.434
KCNC1	MT3	0.434
SNAP25	SLC8A2	0.433
RAB3A	MT3	0.433
HPCA	KCNJ4	0.4320000000000001
GABRD	SYN1	0.4320000000000001
CA10	CDK5R2	0.43
CCK	ATP2B3	0.43
OPALIN	SYN1	0.429
SLC8A2	SLC32A1	0.429
NTSR2	SLC8A2	0.428
STMN2	HPCA	0.427
VSTM2B	ACTL6B	0.427
HRH3	ACTL6B	0.427
HRH3	KCNC1	0.425
FAM163B	SNAP25	0.425
HTR5A	ACTL6B	0.425
CAMK2A	GABRD	0.425
CCK	VSTM2B	0.424
FAM163B	ACTL6B	0.424
ELAVL4	SYN1	0.422
CDK5R2	RAB3A	0.422
CPLX2	VSTM2B	0.422
CPLX1	KCNC1	0.422
SYNPR	CDK5R2	0.421
HRH3	UNC5A	0.42
SCRT1	STMN2	0.42
SLC1A2	MT3	0.419
VSTM2B	SLC8A2	0.419
MAPT	NEUROD6	0.418
ELAVL4	APP	0.418
CA10	SYN1	0.417
MAPT	SNCAIP	0.416
ATP2B3	SLC17A7	0.416
SYP	ACTL6B	0.416
CAMK2A	MT3	0.415
FAM163B	NEUROD6	0.415
SLC8A2	ACTL6B	0.414
OPALIN	HRH3	0.414
HPCA	HRH3	0.413
HRH3	KCNJ4	0.412
CAMK2A	CPLX1	0.412
OPALIN	KCNJ4	0.411
SLC8A2	SLC17A7	0.411
OPALIN	CPLX2	0.41
NEUROD6	RAB3A	0.409
SYN1	MT3	0.409
OPALIN	SLC1A2	0.409
CAMK2A	SLC1A2	0.408
SLC32A1	ACTL6B	0.408
CA10	HRH3	0.408
HTR5A	SLC1A2	0.408
HTR5A	SYP	0.408
ATP2B3	SYP	0.407
HPCA	CPLX2	0.406
NTSR2	SYN1	0.406
NTSR2	KCNC1	0.405
SYNPR	KCNJ4	0.404
FAM163B	CPLX1	0.403
HPCA	NEUROD6	0.403
KCNJ9	SLC1A2	0.403
STMN2	CAMK2A	0.403
CCK	SLC8A2	0.403
KCNJ4	SLC8A2	0.401
HRH3	CDK5R2	0.401
NTSR2	SYP	0.401
CCK	KCNJ4	0.4

Gene Ontology Semantic Similarity

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#	6616 (SNAP25)	57030 (SLC17A7)	6853 (SYN1)	885 (CCK)	815 (CAMK2A)	5864 (RAB3A)	4137 (MAPT)	115827 (RAB3C)	51552 (RAB14)	51762 (RAB8B)	6855 (SYP)	23620 (NTSR2)	3361 (HTR5A)	4520 (MTF1)	492 (ATP2B3)	3208 (HPCA)	6506 (SLC1A2)	351 (APP)	132204 (SYNPR)	6620 (SNCB)	11075 (STMN2)	128229 (TSACC)	3765 (KCNJ9)	83482 (SCRT1)	3746 (KCNC1)	7345 (UCHL1)	9063 (PIAS2)	1996 (ELAVL4)	2563 (GABRD)	9627 (SNCAIP)	3761 (KCNJ4)	56934 (CA10)	140679 (SLC32A1)	6543 (SLC8A2)	4504 (MT3)	51412 (ACTL6B)
6616 (SNAP25)	1.00	0.09	0.67	0.58	0.58	0.71	0.67	0.71	0.59	0.67	0.62	0.14	0.22	0.51	0.64	0.54	0.56	0.71	1.00	0.29	0.87	0.84	0.62	0.26	0.06	0.55	0.60	0.31	0.73	0.81	0.63	0.48	0.09	0.06	0.53	0.22
57030 (SLC17A7)	0.09	1.00	0.19	0.06	0.08	0.08	0.08	0.08	0.07	0.08	0.07	0.06	0.06	0.08	0.28	0.06	0.66	0.08	0.12	0.05	0.09	0.09	0.23	0.12	0.29	0.07	0.08	0.05	0.09	0.09	0.21	0.21	0.59	0.50	0.09	0.09
6853 (SYN1)	0.67	0.19	1.00	0.45	0.50	0.55	0.63	0.55	0.68	0.68	0.48	0.18	0.24	0.43	0.53	0.42	0.47	0.63	1.00	0.27	0.66	0.65	0.49	0.34	0.11	0.47	0.50	0.29	0.54	0.64	0.51	0.64	0.17	0.18	0.46	0.23
885 (CCK)	0.58	0.06	0.45	1.00	0.41	0.49	0.47	0.49	0.39	0.55	0.45	0.10	0.16	0.32	0.43	0.39	0.36	0.56	0.69	0.20	0.60	0.63	0.41	0.18	0.04	0.37	0.42	0.22	0.52	0.59	0.42	0.32	0.06	0.04	0.34	0.16
815 (CAMK2A)	0.58	0.08	0.50	0.41	1.00	0.50	0.62	0.50	0.45	0.51	0.41	0.14	0.18	0.41	0.47	0.36	0.42	0.59	1.00	0.24	0.57	0.56	0.44	0.26	0.05	0.46	0.55	0.23	0.49	0.57	0.46	0.48	0.08	0.06	0.46	0.19
5864 (RAB3A)	0.71	0.08	0.55	0.49	0.50	1.00	0.63	1.00	0.79	0.80	0.50	0.14	0.19	0.41	0.56	0.48	0.43	0.64	1.00	0.25	0.71	0.71	0.47	0.26	0.05	0.50	0.51	0.27	0.57	0.69	0.51	0.48	0.08	0.06	0.45	0.20
4137 (MAPT)	0.67	0.08	0.63	0.47	0.62	0.63	1.00	0.63	0.59	0.63	0.52	0.21	0.24	0.63	0.60	0.53	0.57	0.76	1.00	0.25	0.70	0.67	0.59	0.26	0.05	0.57	0.59	0.34	0.63	0.70	0.60	0.48	0.08	0.06	0.56	0.18
115827 (RAB3C)	0.71	0.08	0.55	0.49	0.50	1.00	0.63	1.00	0.79	0.80	0.50	0.14	0.19	0.41	0.56	0.48	0.43	0.64	1.00	0.25	0.71	0.71	0.47	0.26	0.05	0.50	0.51	0.27	0.57	0.69	0.51	0.48	0.08	0.06	0.45	0.20
51552 (RAB14)	0.59	0.07	0.68	0.39	0.45	0.79	0.59	0.79	1.00	0.92	0.41	0.14	0.22	0.38	0.47	0.40	0.37	0.57	1.00	0.24	0.57	0.55	0.40	0.26	0.04	0.45	0.45	0.27	0.45	0.56	0.43	0.48	0.07	0.06	0.40	0.16
51762 (RAB8B)	0.67	0.08	0.68	0.55	0.51	0.80	0.63	0.80	0.92	1.00	0.48	0.14	0.22	0.42	0.54	0.43	0.42	0.65	1.00	0.26	0.66	0.66	0.46	0.26	0.05	0.50	0.51	0.28	0.54	0.65	0.49	0.48	0.08	0.06	0.44	0.19
6855 (SYP)	0.62	0.07	0.48	0.45	0.41	0.50	0.52	0.50	0.41	0.48	1.00	0.12	0.20	0.34	0.43	0.40	0.35	0.54	0.82	0.23	0.63	0.64	0.40	0.21	0.05	0.38	0.42	0.28	0.50	0.61	0.43	0.38	0.07	0.05	0.36	0.17
23620 (NTSR2)	0.14	0.06	0.18	0.10	0.14	0.14	0.21	0.14	0.14	0.14	0.12	1.00	0.77	0.14	0.14	0.10	0.14	0.14	0.14	0.09	0.14	0.14	0.19	0.14	0.04	0.14	0.14	0.09	0.72	0.14	0.19	0.24	0.06	0.04	0.18	0.14
3361 (HTR5A)	0.22	0.06	0.24	0.16	0.18	0.19	0.24	0.19	0.22	0.22	0.20	0.77	1.00	0.25	0.17	0.25	0.15	0.25	0.29	0.26	0.22	0.22	0.20	0.18	0.04	0.16	0.18	0.32	0.45	0.22	0.20	0.30	0.06	0.05	0.25	0.14
4520 (MTF1)	0.51	0.08	0.43	0.32	0.41	0.41	0.63	0.41	0.38	0.42	0.34	0.14	0.25	1.00	0.38	0.30	0.33	0.64	1.00	0.21	0.49	0.47	0.35	1.00	0.05	0.38	0.52	0.43	0.39	0.48	0.38	0.48	0.07	0.06	0.38	0.36
492 (ATP2B3)	0.64	0.28	0.53	0.43	0.47	0.56	0.60	0.56	0.47	0.54	0.43	0.14	0.17	0.38	1.00	0.38	0.54	0.59	1.00	0.23	0.62	0.61	0.58	0.26	0.28	0.44	0.47	0.24	0.50	0.61	0.67	0.48	0.26	0.62	0.42	0.17
3208 (HPCA)	0.54	0.06	0.42	0.39	0.36	0.48	0.53	0.48	0.40	0.43	0.40	0.10	0.25	0.30	0.38	1.00	0.32	0.47	0.69	0.61	0.60	0.57	0.36	0.18	0.04	0.33	0.37	0.22	0.46	0.54	0.38	0.32	0.06	0.04	0.47	0.16
6506 (SLC1A2)	0.56	0.66	0.47	0.36	0.42	0.43	0.57	0.43	0.37	0.42	0.35	0.14	0.15	0.33	0.54	0.32	1.00	0.53	1.00	0.21	0.54	0.51	0.46	0.26	0.23	0.38	0.41	0.21	0.40	0.52	0.49	0.48	0.68	0.44	0.37	0.16
351 (APP)	0.71	0.08	0.63	0.56	0.59	0.64	0.76	0.64	0.57	0.65	0.54	0.14	0.25	0.64	0.59	0.47	0.53	1.00	1.00	0.31	0.71	0.72	0.57	0.26	0.05	0.55	0.58	0.43	0.64	0.75	0.59	0.48	0.08	0.06	0.60	0.20
132204 (SYNPR)	1.00	0.12	1.00	0.69	1.00	1.00	1.00	1.00	1.00	1.00	0.82	0.14	0.29	1.00	1.00	0.69	1.00	1.00	1.00	0.36	1.00	1.00	1.00	0.26	0.07	1.00	1.00	0.37	1.00	1.00	1.00	0.48	0.11	0.06	1.00	0.26
6620 (SNCB)	0.29	0.05	0.27	0.20	0.24	0.25	0.25	0.25	0.24	0.26	0.23	0.09	0.26	0.21	0.23	0.61	0.21	0.31	0.36	1.00	0.29	0.30	0.23	0.16	0.03	0.20	0.22	0.18	0.27	0.29	0.23	0.28	0.06	0.04	0.58	0.14
11075 (STMN2)	0.87	0.09	0.66	0.60	0.57	0.71	0.70	0.71	0.57	0.66	0.63	0.14	0.22	0.49	0.62	0.60	0.54	0.71	1.00	0.29	1.00	0.86	0.60	0.26	0.06	0.53	0.59	0.31	0.73	0.82	0.62	0.48	0.09	0.06	0.51	0.22
128229 (TSACC)	0.84	0.09	0.65	0.63	0.56	0.71	0.67	0.71	0.55	0.66	0.64	0.14	0.22	0.47	0.61	0.57	0.51	0.72	1.00	0.30	0.86	1.00	0.59	0.26	0.06	0.52	0.58	0.33	0.74	0.85	0.60	0.48	0.09	0.06	0.49	0.23
3765 (KCNJ9)	0.62	0.23	0.49	0.41	0.44	0.47	0.59	0.47	0.40	0.46	0.40	0.19	0.20	0.35	0.58	0.36	0.46	0.57	1.00	0.23	0.60	0.59	1.00	0.26	0.68	0.41	0.44	0.24	0.50	0.59	0.96	0.48	0.24	0.31	0.39	0.16
83482 (SCRT1)	0.26	0.12	0.34	0.18	0.26	0.26	0.26	0.26	0.26	0.26	0.21	0.14	0.18	1.00	0.26	0.18	0.26	0.26	0.26	0.16	0.26	0.26	0.26	1.00	0.07	0.26	0.26	0.16	0.26	0.26	0.26	0.48	0.11	0.06	0.34	0.26
3746 (KCNC1)	0.06	0.29	0.11	0.04	0.05	0.05	0.05	0.05	0.04	0.05	0.05	0.04	0.04	0.05	0.28	0.04	0.23	0.05	0.07	0.03	0.06	0.06	0.68	0.07	1.00	0.04	0.05	0.04	0.06	0.06	0.57	0.11	0.30	0.36	0.05	0.06
7345 (UCHL1)	0.55	0.07	0.47	0.37	0.46	0.50	0.57	0.50	0.45	0.50	0.38	0.14	0.16	0.38	0.44	0.33	0.38	0.55	1.00	0.20	0.53	0.52	0.41	0.26	0.04	1.00	0.46	0.21	0.45	0.60	0.43	0.48	0.07	0.06	0.41	0.17
9063 (PIAS2)	0.60	0.08	0.50	0.42	0.55	0.51	0.59	0.51	0.45	0.51	0.42	0.14	0.18	0.52	0.47	0.37	0.41	0.58	1.00	0.22	0.59	0.58	0.44	0.26	0.05	0.46	1.00	0.24	0.49	0.58	0.46	0.48	0.08	0.06	0.43	0.40
1996 (ELAVL4)	0.31	0.05	0.29	0.22	0.23	0.27	0.34	0.27	0.27	0.28	0.28	0.09	0.32	0.43	0.24	0.22	0.21	0.43	0.37	0.18	0.31	0.33	0.24	0.16	0.04	0.21	0.24	1.00	0.28	0.31	0.24	0.28	0.06	0.04	0.24	0.14
2563 (GABRD)	0.73	0.09	0.54	0.52	0.49	0.57	0.63	0.57	0.45	0.54	0.50	0.72	0.45	0.39	0.50	0.46	0.40	0.64	1.00	0.27	0.73	0.74	0.50	0.26	0.06	0.45	0.49	0.28	1.00	0.71	0.53	0.48	0.08	0.06	0.43	0.21
9627 (SNCAIP)	0.81	0.09	0.64	0.59	0.57	0.69	0.70	0.69	0.56	0.65	0.61	0.14	0.22	0.48	0.61	0.54	0.52	0.75	1.00	0.29	0.82	0.85	0.59	0.26	0.06	0.60	0.58	0.31	0.71	1.00	0.60	0.48	0.09	0.06	0.50	0.22
3761 (KCNJ4)	0.63	0.21	0.51	0.42	0.46	0.51	0.60	0.51	0.43	0.49	0.43	0.19	0.20	0.38	0.67	0.38	0.49	0.59	1.00	0.23	0.62	0.60	0.96	0.26	0.57	0.43	0.46	0.24	0.53	0.60	1.00	0.48	0.21	0.31	0.41	0.17
56934 (CA10)	0.48	0.21	0.64	0.32	0.48	0.48	0.48	0.48	0.48	0.48	0.38	0.24	0.30	0.48	0.48	0.32	0.48	0.48	0.48	0.28	0.48	0.48	0.48	0.48	0.11	0.48	0.48	0.28	0.48	0.48	0.48	1.00	0.18	0.10	0.64	0.48
140679 (SLC32A1)	0.09	0.59	0.17	0.06	0.08	0.08	0.08	0.08	0.07	0.08	0.07	0.06	0.06	0.07	0.26	0.06	0.68	0.08	0.11	0.06	0.09	0.09	0.24	0.11	0.30	0.07	0.08	0.06	0.08	0.09	0.21	0.18	1.00	0.49	0.08	0.09
6543 (SLC8A2)	0.06	0.50	0.18	0.04	0.06	0.06	0.06	0.06	0.06	0.06	0.05	0.04	0.05	0.06	0.62	0.04	0.44	0.06	0.06	0.04	0.06	0.06	0.31	0.06	0.36	0.06	0.06	0.04	0.06	0.06	0.31	0.10	0.49	1.00	0.08	0.06
4504 (MT3)	0.53	0.09	0.46	0.34	0.46	0.45	0.56	0.45	0.40	0.44	0.36	0.18	0.25	0.38	0.42	0.47	0.37	0.60	1.00	0.58	0.51	0.49	0.39	0.34	0.05	0.41	0.43	0.24	0.43	0.50	0.41	0.64	0.08	0.08	1.00	0.21
51412 (ACTL6B)	0.22	0.09	0.23	0.16	0.19	0.20	0.18	0.20	0.16	0.19	0.17	0.14	0.14	0.36	0.17	0.16	0.16	0.20	0.26	0.14	0.22	0.23	0.16	0.26	0.06	0.17	0.40	0.14	0.21	0.22	0.17	0.48	0.09	0.06	0.21	1.00

Association with High Altitude

Protein Official symbol	Source Organism	Tissue of Expression	Level of hypoxia	Altitude	Duration of experiment	Level of expression	Fold change	Experiment details	geographical location	ethnicity of the patients	Control group	Control (Fold change)	Reference (PMID)
SNCB	Rat	Left brain cortices	300hPa	9144 m	1 hour	upregulated	1.54±0.2	TMT labeled LTQ orbitrap	Southwestern europe	Male wistar rats	1	Adult male Wistar rats weighing 350 g	28697276

Association with TF

TF	TF Entrez	Gene	Gene Entrez	Type	PMID	Database
MTF1	4520	SNCB	6620	Unknown	14521756	TRUSST

Association with miRNA

miRTarBase ID	miRNA	Species (miRNA)	Protein Official Symbol	Human Entrez ID	Species (Target Gene)	Experiments	Support Type	References (PMID)
MIRT018267	hsa-miR-335-5p	Homo sapiens	SNCB	6620	Homo sapiens	Microarray	Functional MTI (Weak)	18185580
MIRT544931	hsa-miR-4773	Homo sapiens	SNCB	6620	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT544932	hsa-miR-376c-3p	Homo sapiens	SNCB	6620	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT544935	hsa-miR-548j-3p	Homo sapiens	SNCB	6620	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT544937	hsa-miR-548am-3p	Homo sapiens	SNCB	6620	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT544934	hsa-miR-548x-3p	Homo sapiens	SNCB	6620	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT544933	hsa-miR-4789-3p	Homo sapiens	SNCB	6620	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT544939	hsa-miR-548ah-3p	Homo sapiens	SNCB	6620	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT544944	hsa-miR-548bb-3p	Homo sapiens	SNCB	6620	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT544942	hsa-miR-548h-3p	Homo sapiens	SNCB	6620	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT544945	hsa-miR-548ac	Homo sapiens	SNCB	6620	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT544938	hsa-miR-548aj-3p	Homo sapiens	SNCB	6620	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT544943	hsa-miR-548d-3p	Homo sapiens	SNCB	6620	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT544936	hsa-miR-548aq-3p	Homo sapiens	SNCB	6620	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT544941	hsa-miR-548z	Homo sapiens	SNCB	6620	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407
MIRT544940	hsa-miR-548ae-3p	Homo sapiens	SNCB	6620	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	21572407

Gene Ontology

ID	GO ID	GO Term	GO Type
6620	GO:0050808	synapse organization	GOTERM_BP_DIRECT
6620	GO:0005509	calcium ion binding	GOTERM_MF_DIRECT
6620	GO:0004859	enzyme inhibitor activity	GOTERM_MF_DIRECT
6620	GO:0005794	Golgi apparatus	GOTERM_CC_DIRECT
6620	GO:0043086	negative regulation of catalytic activity	GOTERM_BP_DIRECT
6620	GO:0043524	negative regulation of neuron apoptotic process	GOTERM_BP_DIRECT
6620	GO:0005739	mitochondrion	GOTERM_CC_DIRECT
6620	GO:0042417	dopamine metabolic process	GOTERM_BP_DIRECT
6620	GO:0005737	cytoplasm	GOTERM_CC_DIRECT
6620	GO:0045202	synapse	GOTERM_CC_DIRECT
6620	GO:0007268	chemical synaptic transmission	GOTERM_BP_DIRECT
6620	GO:0016234	inclusion body	GOTERM_CC_DIRECT
6620	GO:0005654	nucleoplasm	GOTERM_CC_DIRECT

Pathways

Human Entrez ID	KEGG ID	KEGG Term

Association with Disease

Protein Official Symbol	Human Entrez ID	Disease Name	Disease Id	Disease Semantic Type	Semantic score	DSI	DPI	Disease Type
SNCB	6620	Lewy Body Disease	C0752347	Disease or Syndrome	0.47	0.707	0.241	disease
SNCB	6620	Schizophrenia	C0036341	Mental or Behavioral Dysfunction	0.31	0.707	0.241	disease

Association with Drug

Protein Official Symbol	Human Entrez ID	drug_claim_primary_name	drug_name	drug_chembl_id	interaction_types