ALTITUDEOMICSDB

Desmin

AltitudeomicsDB

Protein Official symbol	DES
Aliases	DES
Chromosomal Location	2
Length	470
Uniprot ID	P17661
EC number	None
Protein family Information(Pfam)	PF00038;PF04732;
PDB id	None
InterPro ID	IPR018039;IPR039008;IPR042180;IPR006821;
dbSNP	rs58999456 rs903985237 rs62636495 rs60798368 rs60794845 rs60794845 rs267607499 rs397516695 rs41272699 rs201945924 rs267607486 rs59962885 rs57496341 rs267607482 rs57639980 rs57965306 rs61368398 rs58898021 rs121913000 rs59308628 rs57955682 rs121913004 rs121913001 rs61130669 rs57694264 rs121913003 rs62635763 rs121913005 rs267607485 rs121913002 rs267607488 rs267607490 rs267607491

Protein Protein Interaction

Download Tab separated file

AltitudeomicsDB

Protein 1	Protein 2	Combine Score
TNNI2	TNNC1	0.9990000000000001
TNNI2	TNNC2	0.9990000000000001
TNNI2	TNNT3	0.9990000000000001
NEB	TTN	0.9990000000000001
TNNC2	TNNT3	0.9990000000000001
TNNI3	TNNC1	0.9990000000000001
TNNI3	TNNT2	0.998
MYH6	TNNI1	0.998
TTN	TCAP	0.998
MYH3	TNNI1	0.997
ACTN2	MYH6	0.997
TNNI1	TNNC1	0.996
MYH3	ACTN2	0.996
NEB	MYL1	0.996
MYH6	TPM1	0.996
TNNI1	TNNT2	0.995
TNNI2	MYL1	0.995
ACTN2	TPM1	0.995
MYL1	TNNT3	0.995
ACTN2	TPM2	0.995
TNNI1	TPM1	0.995
TPM2	TNNI1	0.995
TTN	TNNC2	0.995
MYH3	TPM2	0.9940000000000001
MYH6	TPM2	0.9940000000000001
TNNT1	TNNI1	0.9940000000000001
ACTN2	TNNI1	0.9940000000000001
TTN	MYL1	0.9940000000000001
TNNT1	TNNI3	0.993
TNNC2	MYL1	0.993
TPM1	TNNT2	0.993
TNNI1	TNNT3	0.993
MYBPC3	TNNT2	0.992
NEB	TNNC2	0.992
MYBPC3	MYH6	0.992
MYH8	TPM1	0.992
ACTN2	MYH8	0.991
MYL3	MYL2	0.991
TNNT1	TNNI2	0.991
MYH8	MYL1	0.991
MYH6	TNNT2	0.991
MYH6	MYL2	0.991
MYH6	MYL3	0.99
TTN	ACTN2	0.99
TNNI3	TNNT3	0.9890000000000001
TNNC2	TNNI3	0.988
TNNI2	TPM2	0.988
TPM2	TNNT3	0.988
TNNT2	TNNC1	0.987
VIM	DES	0.987
MYH6	TNNI3	0.987
ACTN2	TNNT2	0.987
TPM1	TNNI3	0.986
TNNT1	TNNC1	0.986
MYBPC3	TNNI3	0.986
TPM3	TPM1	0.986
TNNT1	TPM1	0.985
TNNT2	MYL2	0.985
TPM1	MYL2	0.985
TPM3	TMOD1	0.985
MYL3	TNNI3	0.985
MYH6	MYL1	0.9840000000000001
TPM2	TPM1	0.983
NEB	TMOD4	0.983
TNNI3	MYL2	0.983
MYL3	TNNT2	0.983
NEB	TMOD1	0.983
MYH3	MYL1	0.983
MYBPC3	MYL2	0.983
MYH6	MYL4	0.982
MYL3	TNNI1	0.982
TNNT1	TPM3	0.981
TPM1	TNNT3	0.981
MYH8	MYL4	0.981
TNNC2	TNNT2	0.981
MYBPC3	MYL3	0.981
MYH3	MYL4	0.981
TTN	MYH6	0.981
MYH8	MYL3	0.981
TNNI2	TNNT2	0.98
MYH8	MYL2	0.98
MYBPC3	TPM1	0.98
MYH3	MYL3	0.98
TNNT1	TPM2	0.98
MYBPC2	TNNT3	0.98
MYL3	TPM1	0.9790000000000001
NEB	TPM2	0.9790000000000001
TPM2	TPM3	0.9790000000000001
TNNC2	TNNI1	0.978
TTN	ACTN3	0.978
MYH3	MYL2	0.978
TPM1	TPM4	0.977
TNNT3	TNNC1	0.977
MYH3	TNNI2	0.977
TPM3	TNNT2	0.977
MYBPC1	TNNI2	0.976
TTN	MYL2	0.976
TPM3	TNNT3	0.976
MYBPC1	TNNT3	0.976
TPM1	TMOD1	0.976
TTN	MYL3	0.976
TNNC2	TPM4	0.976
MYH3	TNNT3	0.976
ACTN3	TNNT3	0.976
ACTN2	TNNT3	0.975
TPM3	TNNI1	0.9740000000000001
ACTN2	TPM4	0.9740000000000001
TNNI3	MYL1	0.9740000000000001
TPM2	TPM4	0.9740000000000001
ACTN2	TPM3	0.9740000000000001
TTN	TNNT2	0.9740000000000001
TTN	TNNI3	0.9740000000000001
TPM3	TMOD3	0.9740000000000001
TNNI2	TPM1	0.9740000000000001
MYL1	TNNT2	0.973
TNNI1	MYL4	0.972
TNNI1	MYL1	0.972
TPM2	TNNT2	0.972
TTN	DMD	0.972
TNNC2	MYBPC2	0.972
TPM2	MYL1	0.972
ACTN2	MYL2	0.972
ACTN3	TNNC2	0.971
TPM4	TNNT3	0.971
TNNI2	TPM4	0.971
TPM3	MYL1	0.971
TTN	TNNT3	0.971
TPM2	TNNC2	0.971
TNNC2	TPM1	0.971
MYL3	TNNI2	0.971
TPM1	TMOD2	0.97
MYH6	TNNC1	0.97
MYH8	TNNT3	0.97
TNNI1	MYL2	0.97
MYBPC3	TCAP	0.97
TNNI2	TPM3	0.97
MYL3	TNNT3	0.97
TPM3	TMOD2	0.97
MYL4	TNNI3	0.97
ACTN3	TNNI2	0.9690000000000001
ACTN3	MYBPC2	0.9690000000000001
TNNT1	MYL2	0.9690000000000001
TNNT1	TPM4	0.9690000000000001
TTN	MYL4	0.9690000000000001
ACTN2	TCAP	0.9690000000000001
NEB	TPM3	0.9690000000000001
ACTN2	TNNC2	0.968
TPM4	TMOD3	0.968
TTN	MYH3	0.968
TCAP	TNNT2	0.968
TTN	MYH8	0.968
MYL4	TNNT2	0.968
MYH6	TCAP	0.968
MYL3	TCAP	0.968
ACTN2	MYL3	0.968
TNNT1	MYL3	0.968
TPM1	MYL1	0.968
MYH6	TNNT3	0.9670000000000001
MYH3	TNNC2	0.9670000000000001
TPM4	TNNT2	0.9670000000000001
ACTN3	TPM2	0.966
TNNI2	MYL4	0.966
TNNT1	TNNC2	0.966
TPM4	MYL1	0.966
TPM2	TMOD1	0.966
TNNT3	MYL2	0.966
NEB	TPM1	0.966
ACTN2	TNNI3	0.966
TCAP	MYL2	0.966
TNNI2	MYBPC2	0.966
MYL3	TPM2	0.965
TNNI3	TCAP	0.965
MYBPC1	MYL1	0.965
ACTN3	TPM1	0.965
TNNT1	MYL4	0.965
ACTN2	MYBPC3	0.9640000000000001
ACTN3	TNNT2	0.9640000000000001
TNNI2	MYL2	0.9640000000000001
MYH6	TNNC2	0.9640000000000001
TTN	TPM1	0.9640000000000001
ACTN3	MYH6	0.9640000000000001
TNNT1	MYL1	0.9640000000000001
TTN	MYBPC3	0.963
TPM2	TNNI3	0.963
TPM2	TMOD3	0.963
MYH8	TPM2	0.963
ACTN2	MYL1	0.963
MYH3	TNNT2	0.9620000000000001
NEB	TNNT3	0.9620000000000001
MYH8	TNNI3	0.9620000000000001
MYL3	TPM3	0.9620000000000001
NEB	TCAP	0.9620000000000001
TPM4	TMOD1	0.9620000000000001
MYH8	TNNC2	0.9620000000000001
NEB	TNNT1	0.961
MYH6	DMD	0.961
MYH6	TPM3	0.961
TPM3	TNNI3	0.961
TNNT1	MYH6	0.961
TPM1	TMOD3	0.96
ACTN3	MYH8	0.96
TTN	TNNC1	0.96
TNNT1	TTN	0.96
MYH3	TNNI3	0.96
TPM2	MYL2	0.9590000000000001
TTN	TNNI1	0.9590000000000001
TPM1	TCAP	0.9590000000000001
MYL4	TNNT3	0.9590000000000001
MYBPC1	TNNI1	0.9590000000000001
MYH6	TNNI2	0.9590000000000001
MYH8	TNNI1	0.9590000000000001
TPM3	MYL2	0.9590000000000001
TNNI1	TPM4	0.9590000000000001
ACTN3	MYL1	0.9590000000000001
TPM2	MYL4	0.9590000000000001
ACTN3	TPM4	0.9590000000000001
TPM4	TNNI3	0.958
NEB	DES	0.958
MYH6	TPM4	0.958
ACTN3	TPM3	0.958
TNNC1	MYL2	0.9570000000000001
NEB	MYH8	0.9570000000000001
MYL3	TPM4	0.9570000000000001
MYH8	TNNT2	0.9570000000000001
NEB	MYH6	0.9570000000000001
MYH8	TNNI2	0.9570000000000001
TPM2	TMOD2	0.956
NEB	DMD	0.956
TPM4	MYL2	0.956
MYBPC3	TPM3	0.956
MYL4	TPM4	0.956
TPM3	MYL4	0.956
TPM4	TMOD2	0.955
MYH3	ACTN3	0.955
TPM2	TMOD4	0.955
TPM1	TNNC1	0.955
TPM1	MYL4	0.955
NEB	MYH3	0.9540000000000001
NEB	ACTN2	0.9540000000000001
DMD	TCAP	0.9540000000000001
MYH8	MYBPC2	0.9540000000000001
TTN	MYBPC1	0.9540000000000001
TPM3	TMOD4	0.9540000000000001
TNNC2	TPM3	0.9540000000000001
MYBPC1	MYL3	0.9540000000000001
TTN	TNNI2	0.9540000000000001
TTN	TPM2	0.9540000000000001
MYH3	TPM1	0.953
MYH8	TPM4	0.9520000000000001
MYBPC1	TNNC2	0.9520000000000001
NEB	MYBPC2	0.9520000000000001
TNNT1	ACTN2	0.9520000000000001
NEB	ACTN3	0.951
MYH8	TPM3	0.951
MYBPC3	MYL4	0.951
MYH3	DMD	0.951
TNNI1	MYBPC2	0.95
ACTN2	TNNI2	0.95
TNNT1	MYBPC1	0.95
MYH3	TPM3	0.95
MYH3	TPM4	0.95
TTN	DES	0.95
MYBPC1	TPM2	0.9490000000000001
TPM4	TMOD4	0.9490000000000001
TTN	TPM3	0.9490000000000001
MYH8	DMD	0.948
TNNT1	MYH8	0.948
NEB	TMOD3	0.948
TNNT1	MYH3	0.948
TPM1	TMOD4	0.948
MYBPC1	MYH8	0.9470000000000001
ACTN2	MYL4	0.9470000000000001
TPM3	TNNC1	0.9470000000000001
TPM2	TNNC1	0.9470000000000001
TNNT1	ACTN3	0.9470000000000001
ACTN3	MYL2	0.946
DMD	TPM1	0.946
ACTN2	TNNC1	0.946
NEB	TPM4	0.946
MYH6	MYBPC2	0.946
TPM3	DMD	0.946
TPM2	DMD	0.946
MYBPC2	MYL1	0.946
DES	AURKB	0.946
DES	TCAP	0.946
ACTN2	DES	0.946
TTN	TPM4	0.945
MYBPC3	TNNC1	0.945
TNNT1	MYBPC2	0.945
MYBPC3	TNNI1	0.945
TNNT1	MYBPC3	0.9440000000000001
ACTN3	MYL3	0.9440000000000001
MYBPC3	DES	0.9440000000000001
TCAP	MYL1	0.9440000000000001
MYBPC1	TNNT2	0.943
MYH3	MYBPC1	0.943
TTN	TMOD1	0.943
MYL3	TNNC1	0.9420000000000001
NEB	MYBPC1	0.9420000000000001
ACTN3	TMOD4	0.9420000000000001
MYL3	DMD	0.9420000000000001
NEB	MYL2	0.941
ACTN2	MYBPC2	0.941
NEB	TNNI2	0.941
MYBPC3	TNNT3	0.941
ACTN3	TNNI1	0.94
MYL4	TCAP	0.94
DMD	TNNI3	0.94
MYBPC2	TNNC1	0.94
MYBPC3	MYL1	0.94
NEB	MYL3	0.94
DES	TNNI3	0.94
DES	TPM1	0.94
ACTN2	MYBPC1	0.9390000000000001
MYBPC1	TMOD4	0.9390000000000001
MYH8	TNNC1	0.9390000000000001
TNNC2	TCAP	0.9390000000000001
NEB	MYL4	0.9390000000000001
ACTN2	ACTN3	0.9390000000000001
DMD	TNNT2	0.9390000000000001
DES	TNNT2	0.9390000000000001
DES	TNNC2	0.938
MYBPC2	MYL2	0.938
DMD	MYL1	0.938
ACTN3	MYL4	0.938
TMOD4	TNNT3	0.938
TPM2	MYBPC2	0.938
MYL3	MYBPC2	0.938
TPM3	TPM4	0.938
MYL1	MYL2	0.938
MYBPC1	MYH6	0.937
DMD	TPM4	0.937
MYBPC1	MYL4	0.937
DES	MYL1	0.937
MYBPC2	TNNT2	0.937
ACTN3	TNNC1	0.9359999999999999
MYBPC3	TMOD1	0.9359999999999999
TNNI2	TMOD1	0.9359999999999999
TNNT1	TMOD4	0.9359999999999999
MYL1	TMOD4	0.935
TPM1	MYBPC2	0.935
ACTN3	TCAP	0.935
MYH3	TCAP	0.935
TCAP	TMOD4	0.935
NEB	TNNT2	0.935
MYBPC1	DMD	0.935
TTN	TMOD4	0.935
MYH6	DES	0.935
MYBPC1	MYL2	0.935
MYBPC3	TNNI2	0.935
MYH3	MYBPC2	0.934
DMD	MYL2	0.934
TPM4	TNNC1	0.934
TNNT3	TMOD1	0.934
TNNI2	TCAP	0.934
NEB	TNNI1	0.9329999999999999
MYBPC1	TNNI3	0.9329999999999999
TNNC2	TNNC1	0.932
TCAP	TNNT3	0.932
MYH3	TNNC1	0.932
MYBPC1	TNNC1	0.9309999999999999
ACTN3	TMOD1	0.9309999999999999
DMD	TNNT3	0.9309999999999999
TMOD4	TNNC1	0.93
MYBPC3	MYH8	0.93
ACTN3	MYBPC1	0.93
MYBPC3	DMD	0.93
TNNI2	TMOD4	0.93
NEB	MYBPC3	0.93
TMOD1	TNNT2	0.93
TCAP	TNNC1	0.93
NEB	TMOD2	0.93
TPM3	TCAP	0.93
DMD	TNNI1	0.929
TNNI1	TCAP	0.929
NEB	TNNI3	0.929
MYL3	TMOD4	0.9279999999999999
MYH8	TCAP	0.9279999999999999
VIM	TPM2	0.9279999999999999
DMD	MYL4	0.9279999999999999
MYBPC1	TPM1	0.927
TPM3	MYBPC2	0.927
MYBPC1	TPM3	0.927
TNNC2	TMOD4	0.9259999999999999
DMD	TMOD1	0.9259999999999999
ACTN2	DMD	0.9259999999999999
MYL3	DES	0.9259999999999999
MYL1	TNNC1	0.9259999999999999
TNNT1	DMD	0.925
MYL4	TMOD1	0.925
MYBPC2	TMOD4	0.925
MYH3	TMOD1	0.925
VIM	TPM4	0.925
TTN	MYBPC2	0.925
VIM	TPM1	0.925
DES	TNNC1	0.924
TCAP	TMOD1	0.924
TNNI1	TMOD1	0.924
MYH6	TMOD1	0.924
ACTN2	TMOD4	0.924
TPM2	TCAP	0.924
TNNT1	TMOD1	0.924
MYL4	MYL2	0.9229999999999999
MYH3	MYBPC3	0.9229999999999999
TTN	VIM	0.9229999999999999
TMOD4	MYL2	0.9229999999999999
TNNT1	TCAP	0.9229999999999999
ACTN3	TNNI3	0.922
ACTN3	DMD	0.922
MYH8	TMOD4	0.922
TNNI2	DMD	0.922
MYL3	TMOD1	0.922
MYL4	TNNC1	0.922
TNNI3	TMOD1	0.9209999999999999
TNNT1	DES	0.9209999999999999
ACTN3	TMOD3	0.9209999999999999
DES	DMD	0.9209999999999999
TNNC2	DMD	0.9209999999999999
MYBPC3	TPM2	0.9209999999999999
MYH6	TMOD4	0.92
TNNC2	MYL2	0.92
ACTN2	TMOD1	0.92
MYBPC2	TCAP	0.92
MYL3	MYL1	0.92
TNNT1	TNNT2	0.92
MYL3	TNNC2	0.92
ACTN2	TMOD2	0.919
MYL4	TMOD4	0.919
DES	MYL2	0.919
MYBPC3	TPM4	0.919
TNNI2	TMOD3	0.919
VIM	TPM3	0.919
MYBPC2	TNNI3	0.919
MYBPC3	ACTN3	0.9179999999999999
MYBPC3	TNNC2	0.9179999999999999
DMD	TNNC1	0.9179999999999999
VIM	MYH6	0.9179999999999999
TTN	TMOD3	0.9179999999999999
NEB	VIM	0.9179999999999999
TMOD1	TNNC1	0.917
MYH8	TMOD1	0.917
DMD	TMOD3	0.917
MYBPC2	TMOD1	0.917
TPM4	TCAP	0.9159999999999999
MYL1	TMOD1	0.9159999999999999
MYBPC2	MYL4	0.9159999999999999
ACTN2	TMOD3	0.9159999999999999
ACTN3	TMOD2	0.9159999999999999
VIM	TNNC2	0.9159999999999999
VIM	TNNT2	0.915
TNNT1	VIM	0.915
TMOD1	MYL2	0.915
DMD	TMOD4	0.915
DMD	MYBPC2	0.915
DES	TNNT3	0.914
VIM	TNNI2	0.914
DES	TNNI1	0.914
VIM	ACTN2	0.9129999999999999
TMOD3	TNNT3	0.9129999999999999
TPM2	DES	0.9129999999999999
MYBPC2	TPM4	0.9129999999999999
TMOD3	MYL1	0.9129999999999999
TNNI2	TMOD2	0.9129999999999999
TMOD4	TNNT2	0.9129999999999999
TMOD3	TNNT2	0.9129999999999999
MYBPC1	MYBPC2	0.9129999999999999
TNNT3	TMOD2	0.9129999999999999
TMOD2	TNNT2	0.9129999999999999
MYH3	TMOD4	0.9129999999999999
TNNI3	TMOD2	0.912
MYBPC3	TMOD2	0.912
VIM	MYL1	0.912
VIM	ACTN3	0.912
TNNI1	TMOD2	0.912
TNNI1	TMOD3	0.912
ACTN3	DES	0.912
MYBPC3	TMOD3	0.912
TNNI3	TMOD3	0.912
VIM	TNNT3	0.9109999999999999
TNNI2	TNNI1	0.9109999999999999
TTN	TMOD2	0.9109999999999999
DMD	TMOD2	0.9109999999999999
VIM	AURKB	0.9109999999999999
NEB	TNNC1	0.9109999999999999
TNNC2	MYL4	0.91
VIM	TNNI3	0.91
MYL4	MYL1	0.91
TNNT1	TMOD3	0.91
TNNI2	TNNI3	0.91
DES	TPM4	0.909
DES	TPM3	0.909
DES	TMOD1	0.909
VIM	MYBPC3	0.909
TNNT1	TMOD2	0.9079999999999999
TNNI3	TMOD4	0.9079999999999999
VIM	MYL4	0.9079999999999999
MYH6	MYH8	0.9079999999999999
MYH3	TMOD3	0.9079999999999999
MYH3	TMOD2	0.9079999999999999
MYH8	DES	0.9079999999999999
VIM	MYL2	0.9079999999999999
MYH8	TMOD2	0.907
MYH8	TMOD3	0.907
TNNT1	TNNT3	0.907
MYH6	TMOD2	0.907
VIM	DMD	0.907
TNNI1	TMOD4	0.907
MYL1	TMOD2	0.907
TNNI2	DES	0.907
MYH6	TMOD3	0.907
MYBPC3	TMOD4	0.907
TMOD2	TNNC1	0.9059999999999999
MYBPC1	TCAP	0.9059999999999999
VIM	TMOD4	0.9059999999999999
MYBPC1	DES	0.9059999999999999
MYH3	DES	0.9059999999999999
VIM	TNNI1	0.9059999999999999
MYBPC1	TMOD2	0.9059999999999999
VIM	TMOD1	0.905
MYBPC1	TPM4	0.905
TNNT3	TNNT2	0.905
TMOD3	TNNC1	0.905
MYBPC3	MYBPC1	0.905
MYH3	MYH8	0.905
DES	MYBPC2	0.905
TMOD4	TMOD1	0.905
MYL3	TMOD3	0.905
MYBPC3	MYBPC2	0.904
MYBPC1	TMOD1	0.904
MYH3	VIM	0.904
DES	TMOD4	0.904
VIM	TNNC1	0.904
VIM	TCAP	0.904
VIM	MYL3	0.904
VIM	MYH8	0.903
VIM	MYBPC1	0.903
VIM	TMOD2	0.903
TNNI1	TNNI3	0.903
MYBPC1	TMOD3	0.903
DES	MYL4	0.903
DES	TMOD2	0.903
MYL3	TMOD2	0.903
MYH3	MYH6	0.903
VIM	TMOD3	0.903
TMOD4	TMOD2	0.903
MYL3	MYL4	0.903
DES	TMOD3	0.903
TMOD3	TMOD4	0.903
MYL4	TMOD3	0.903
TCAP	TMOD3	0.902
TNNC2	TMOD1	0.902
TMOD3	TMOD1	0.902
VIM	MYBPC2	0.902
TCAP	TMOD2	0.902
MYBPC2	TMOD2	0.902
MYBPC2	TMOD3	0.902
TMOD1	TMOD2	0.902
TMOD2	MYL2	0.902
TMOD3	MYL2	0.902
MYL4	TMOD2	0.902
TMOD3	TMOD2	0.9009999999999999
TNNC2	TMOD3	0.9
TNNC2	TMOD2	0.9

Gene Ontology Semantic Similarity

Download Tab separated file

#	7136 (TNNI2)	4703 (NEB)	7125 (TNNC2)	7137 (TNNI3)	4624 (MYH6)	7273 (TTN)	4621 (MYH3)	88 (ACTN2)	7135 (TNNI1)	4632 (MYL1)	7169 (TPM2)	7138 (TNNT1)	7168 (TPM1)	4607 (MYBPC3)	4626 (MYH8)	4634 (MYL3)	7139 (TNNT2)	7431 (VIM)	7170 (TPM3)	4606 (MYBPC2)	7140 (TNNT3)	4604 (MYBPC1)	89 (ACTN3)	7171 (TPM4)	4635 (MYL4)	8557 (TCAP)	7134 (TNNC1)	1756 (DMD)	1674 (DES)	7111 (TMOD1)	29766 (TMOD3)	4633 (MYL2)	9212 (AURKB)
7136 (TNNI2)	1.00	0.73	0.82	0.82	0.31	0.62	0.50	0.69	1.00	0.26	0.73	0.82	0.77	0.63	0.40	0.61	0.85	0.70	0.70	0.65	0.73	0.66	0.70	0.68	0.69	0.73	0.79	0.77	0.80	1.00	0.49	0.70	0.54
4703 (NEB)	0.73	1.00	0.66	0.66	0.26	0.68	0.39	0.73	1.00	1.00	0.78	0.74	0.83	0.72	0.47	0.74	0.72	0.72	0.83	0.81	0.59	0.79	0.85	0.81	0.47	0.83	0.66	0.82	0.80	0.69	0.49	0.79	0.44
7125 (TNNC2)	0.82	0.66	1.00	0.81	0.31	0.71	0.57	0.67	1.00	0.26	0.72	0.73	0.78	0.66	0.45	0.55	0.80	0.67	0.74	0.70	0.73	0.70	0.66	0.87	0.69	0.69	0.90	0.74	0.73	1.00	0.49	0.80	0.53
7137 (TNNI3)	0.82	0.66	0.81	1.00	0.40	0.68	0.55	0.71	1.00	0.26	0.67	0.70	0.76	0.67	0.46	0.53	0.80	0.67	0.72	0.68	0.74	0.69	0.66	0.70	0.62	0.69	0.79	0.72	0.73	1.00	0.49	0.67	0.56
4624 (MYH6)	0.31	0.26	0.31	0.40	1.00	0.38	0.79	0.34	0.60	0.16	0.22	0.30	0.29	0.29	0.67	0.20	0.33	0.33	0.32	0.26	0.51	0.27	0.30	0.26	0.19	0.33	0.32	0.33	0.31	0.40	0.28	0.27	0.23
7273 (TTN)	0.62	0.68	0.71	0.68	0.38	1.00	0.51	0.70	1.00	1.00	0.61	0.60	0.74	0.77	0.48	0.51	0.63	0.66	0.72	0.79	0.54	0.79	0.68	0.77	0.46	0.69	0.71	0.70	0.70	0.72	0.49	0.72	0.71
4621 (MYH3)	0.50	0.39	0.57	0.55	0.79	0.51	1.00	0.49	0.82	0.21	0.48	0.44	0.53	0.48	0.76	0.34	0.51	0.47	0.54	0.48	0.62	0.49	0.44	0.50	0.46	0.48	0.55	0.49	0.46	0.72	0.40	0.42	0.31
88 (ACTN2)	0.69	0.73	0.67	0.71	0.34	0.70	0.49	1.00	1.00	1.00	0.61	0.68	0.77	0.76	0.48	0.54	0.71	0.71	0.72	0.72	0.60	0.75	0.83	0.71	0.48	0.83	0.71	0.74	0.76	0.84	0.49	0.71	0.58
7135 (TNNI1)	1.00	1.00	1.00	1.00	0.60	1.00	0.82	1.00	1.00	0.26	0.69	1.00	1.00	1.00	0.60	0.60	1.00	1.00	1.00	1.00	0.82	1.00	1.00	1.00	0.60	1.00	1.00	1.00	1.00	0.69	0.49	1.00	1.00
4632 (MYL1)	0.26	1.00	0.26	0.26	0.16	1.00	0.21	1.00	0.26	1.00	1.00	0.26	1.00	1.00	1.00	1.00	0.26	0.59	1.00	1.00	0.21	1.00	1.00	1.00	0.16	1.00	0.26	1.00	0.59	0.18	0.13	1.00	0.26
7169 (TPM2)	0.73	0.78	0.72	0.67	0.22	0.61	0.48	0.61	0.69	1.00	1.00	0.58	0.90	0.71	0.58	0.80	0.72	0.55	0.84	0.82	0.64	0.80	0.68	0.81	0.73	0.66	0.63	0.77	0.68	1.00	0.33	0.73	0.36
7138 (TNNT1)	0.82	0.74	0.73	0.70	0.30	0.60	0.44	0.68	1.00	0.26	0.58	1.00	0.68	0.60	0.35	0.51	0.87	0.70	0.66	0.61	0.73	0.62	0.70	0.64	0.56	0.73	0.71	0.71	0.79	0.70	0.49	0.65	0.51
7168 (TPM1)	0.77	0.83	0.78	0.76	0.29	0.74	0.53	0.77	1.00	1.00	0.90	0.68	1.00	0.80	0.61	0.76	0.78	0.76	0.86	0.85	0.69	0.85	0.78	0.85	0.66	0.80	0.73	0.86	0.89	1.00	0.49	0.80	0.49
4607 (MYBPC3)	0.63	0.72	0.66	0.67	0.29	0.77	0.48	0.76	1.00	1.00	0.71	0.60	0.80	1.00	0.58	0.64	0.64	0.68	0.76	0.86	0.57	0.89	0.72	0.75	0.57	0.75	0.67	0.77	0.75	0.72	0.49	0.75	0.49
4626 (MYH8)	0.40	0.47	0.45	0.46	0.67	0.48	0.76	0.48	0.60	1.00	0.58	0.35	0.61	0.58	1.00	0.49	0.44	0.41	0.59	0.56	0.53	0.57	0.47	0.54	0.42	0.48	0.45	0.55	0.44	0.72	0.28	0.50	0.26
4634 (MYL3)	0.61	0.74	0.55	0.53	0.20	0.51	0.34	0.54	0.60	1.00	0.80	0.51	0.76	0.64	0.49	1.00	0.61	0.48	0.69	0.67	0.53	0.66	0.60	0.65	0.80	0.60	0.48	0.70	0.62	0.86	0.28	0.80	0.33
7139 (TNNT2)	0.85	0.72	0.80	0.80	0.33	0.63	0.51	0.71	1.00	0.26	0.72	0.87	0.78	0.64	0.44	0.61	1.00	0.70	0.70	0.66	0.89	0.67	0.69	0.68	0.67	0.72	0.78	0.76	0.81	1.00	0.49	0.70	0.57
7431 (VIM)	0.70	0.72	0.67	0.67	0.33	0.66	0.47	0.71	1.00	0.59	0.55	0.70	0.76	0.68	0.41	0.48	0.70	1.00	0.69	0.69	0.57	0.69	0.72	0.68	0.46	0.72	0.68	0.73	0.84	0.69	0.49	0.68	0.56
7170 (TPM3)	0.70	0.83	0.74	0.72	0.32	0.72	0.54	0.72	1.00	1.00	0.84	0.66	0.86	0.76	0.59	0.69	0.70	0.69	1.00	0.85	0.60	0.83	0.78	0.85	0.59	0.77	0.72	0.78	0.74	0.72	0.49	0.74	0.49
4606 (MYBPC2)	0.65	0.81	0.70	0.68	0.26	0.79	0.48	0.72	1.00	1.00	0.82	0.61	0.85	0.86	0.56	0.67	0.66	0.69	0.85	1.00	0.57	0.97	0.76	0.83	0.56	0.76	0.69	0.77	0.74	0.72	0.49	0.73	0.44
7140 (TNNT3)	0.73	0.59	0.73	0.74	0.51	0.54	0.62	0.60	0.82	0.21	0.64	0.73	0.69	0.57	0.53	0.53	0.89	0.57	0.60	0.57	1.00	0.58	0.57	0.58	0.59	0.61	0.71	0.66	0.68	1.00	0.40	0.60	0.48
4604 (MYBPC1)	0.66	0.79	0.70	0.69	0.27	0.79	0.49	0.75	1.00	1.00	0.80	0.62	0.85	0.89	0.57	0.66	0.67	0.69	0.83	0.97	0.58	1.00	0.76	0.82	0.56	0.80	0.69	0.77	0.75	0.72	0.49	0.73	0.46
89 (ACTN3)	0.70	0.85	0.66	0.66	0.30	0.68	0.44	0.83	1.00	1.00	0.68	0.70	0.78	0.72	0.47	0.60	0.69	0.72	0.78	0.76	0.57	0.76	1.00	0.76	0.47	0.81	0.73	0.78	0.76	0.69	0.49	0.75	0.51
7171 (TPM4)	0.68	0.81	0.87	0.70	0.26	0.77	0.50	0.71	1.00	1.00	0.81	0.64	0.85	0.75	0.54	0.65	0.68	0.68	0.85	0.83	0.58	0.82	0.76	1.00	0.58	0.76	0.82	0.77	0.72	0.72	0.49	0.87	0.44
4635 (MYL4)	0.69	0.47	0.69	0.62	0.19	0.46	0.46	0.48	0.60	0.16	0.73	0.56	0.66	0.57	0.42	0.80	0.67	0.46	0.59	0.56	0.59	0.56	0.47	0.58	1.00	0.48	0.60	0.59	0.56	0.86	0.28	0.65	0.34
8557 (TCAP)	0.73	0.83	0.69	0.69	0.33	0.69	0.48	0.83	1.00	1.00	0.66	0.73	0.80	0.75	0.48	0.60	0.72	0.72	0.77	0.76	0.61	0.80	0.81	0.76	0.48	1.00	0.69	0.78	0.79	0.70	0.49	0.76	0.58
7134 (TNNC1)	0.79	0.66	0.90	0.79	0.32	0.71	0.55	0.71	1.00	0.26	0.63	0.71	0.73	0.67	0.45	0.48	0.78	0.68	0.72	0.69	0.71	0.69	0.73	0.82	0.60	0.69	1.00	0.69	0.74	0.72	0.49	0.74	0.55
1756 (DMD)	0.77	0.82	0.74	0.72	0.33	0.70	0.49	0.74	1.00	1.00	0.77	0.71	0.86	0.77	0.55	0.70	0.76	0.73	0.78	0.77	0.66	0.77	0.78	0.77	0.59	0.78	0.69	1.00	0.79	1.00	0.49	0.82	0.55
1674 (DES)	0.80	0.80	0.73	0.73	0.31	0.70	0.46	0.76	1.00	0.59	0.68	0.79	0.89	0.75	0.44	0.62	0.81	0.84	0.74	0.74	0.68	0.75	0.76	0.72	0.56	0.79	0.74	0.79	1.00	0.84	0.49	0.74	0.53
7111 (TMOD1)	1.00	0.69	1.00	1.00	0.40	0.72	0.72	0.84	0.69	0.18	1.00	0.70	1.00	0.72	0.72	0.86	1.00	0.69	0.72	0.72	1.00	0.72	0.69	0.72	0.86	0.70	0.72	1.00	0.84	1.00	0.33	0.86	0.69
29766 (TMOD3)	0.49	0.49	0.49	0.49	0.28	0.49	0.40	0.49	0.49	0.13	0.33	0.49	0.49	0.49	0.28	0.28	0.49	0.49	0.49	0.49	0.40	0.49	0.49	0.49	0.28	0.49	0.49	0.49	0.49	0.33	1.00	0.49	0.49
4633 (MYL2)	0.70	0.79	0.80	0.67	0.27	0.72	0.42	0.71	1.00	1.00	0.73	0.65	0.80	0.75	0.50	0.80	0.70	0.68	0.74	0.73	0.60	0.73	0.75	0.87	0.65	0.76	0.74	0.82	0.74	0.86	0.49	1.00	0.47
9212 (AURKB)	0.54	0.44	0.53	0.56	0.23	0.71	0.31	0.58	1.00	0.26	0.36	0.51	0.49	0.49	0.26	0.33	0.57	0.56	0.49	0.44	0.48	0.46	0.51	0.44	0.34	0.58	0.55	0.55	0.53	0.69	0.49	0.47	1.00

Association with High Altitude

Protein Official symbol	Source Organism	Tissue of Expression	Level of hypoxia	Altitude	Duration of experiment	Level of expression	Fold change	Experiment details	geographical location	ethnicity of the patients	Control group	Control (Fold change)	Reference (PMID)
DES	Human	Skeletal muscle	-	4559 m	9 day	downregulated	-1.32	2-DIGE	Southern Europe	Italians	1	Fasting control subjects at laboratory in Copenhagen with no caffeine intake	18937252

Association with TF

TF	TF Entrez	Gene	Gene Entrez	Type	PMID	Database
EP300	2033	DES	1674	distal	22955619	TRANSFAC
TRIM16	10626147166	DES	1674	Unknown	11556541	TRUSST

Association with miRNA

miRTarBase ID	miRNA	Species (miRNA)	Protein Official Symbol	Human Entrez ID	Species (Target Gene)	Experiments	Support Type	References (PMID)

Gene Ontology

ID	GO ID	GO Term	GO Type
1674	GO:0030049	muscle filament sliding	GOTERM_BP_DIRECT
1674	GO:0045109	intermediate filament organization	GOTERM_BP_DIRECT
1674	GO:0005198	structural molecule activity	GOTERM_MF_DIRECT
1674	GO:0008092	cytoskeletal protein binding	GOTERM_MF_DIRECT
1674	GO:0005882	intermediate filament	GOTERM_CC_DIRECT
1674	GO:0006936	muscle contraction	GOTERM_BP_DIRECT
1674	GO:0007010	cytoskeleton organization	GOTERM_BP_DIRECT
1674	GO:0005200	structural constituent of cytoskeleton	GOTERM_MF_DIRECT
1674	GO:0014704	intercalated disc	GOTERM_CC_DIRECT
1674	GO:0008016	regulation of heart contraction	GOTERM_BP_DIRECT
1674	GO:0005515	protein binding	GOTERM_MF_DIRECT
1674	GO:0005916	fascia adherens	GOTERM_CC_DIRECT
1674	GO:0031594	neuromuscular junction	GOTERM_CC_DIRECT
1674	GO:0042383	sarcolemma	GOTERM_CC_DIRECT
1674	GO:0042802	identical protein binding	GOTERM_MF_DIRECT
1674	GO:0005829	cytosol	GOTERM_CC_DIRECT
1674	GO:0030018	Z disc	GOTERM_CC_DIRECT
1674	GO:0045111	intermediate filament cytoskeleton	GOTERM_CC_DIRECT
1674	GO:0070062	extracellular exosome	GOTERM_CC_DIRECT

Pathways

Human Entrez ID	KEGG ID	KEGG Term
1674	hsa05410	Hypertrophic cardiomyopathy
1674	hsa05412	Arrhythmogenic right ventricular cardiomyopathy
1674	hsa05414	Dilated cardiomyopathy

Association with Disease

Protein Official Symbol	Human Entrez ID	Disease Name	Disease Id	Disease Semantic Type	Semantic score	DSI	DPI	Disease Type
DES	1674	MYOPATHY, MYOFIBRILLAR, DESMIN-RELATED	C1832370	Disease or Syndrome	1	0.503	0.759	disease
DES	1674	Malignant neoplasm of stomach	C0024623	Neoplastic Process	0.3	0.503	0.759	disease
DES	1674	Animal Mammary Neoplasms	C0024667	Neoplastic Process	0.3	0.503	0.759	group
DES	1674	Nephrosis	C0027720	Disease or Syndrome	0.3	0.503	0.759	disease
DES	1674	Stomach Neoplasms	C0038356	Neoplastic Process	0.3	0.503	0.759	group
DES	1674	Carcinomatosis	C0205699	Neoplastic Process	0.3	0.503	0.759	phenotype
DES	1674	Malignant neoplasm of breast	C0006142	Neoplastic Process	0.32	0.503	0.759	disease
DES	1674	Fetal Growth Retardation	C0015934	Pathologic Function	0.3	0.503	0.759	phenotype
DES	1674	Glomerulonephritis	C0017658	Disease or Syndrome	0.3	0.503	0.759	disease
DES	1674	Anaplastic carcinoma	C0205696	Neoplastic Process	0.3	0.503	0.759	disease
DES	1674	Breast Carcinoma	C0678222	Neoplastic Process	0.32	0.503	0.759	disease
DES	1674	Mammary Carcinoma, Animal	C1257925	Neoplastic Process	0.3	0.503	0.759	disease
DES	1674	Hereditary Diffuse Gastric Cancer	C1708349	Neoplastic Process	0.3	0.503	0.759	disease
DES	1674	Persistent atrial fibrillation	C2585653	Pathologic Function	0.3	0.503	0.759	phenotype
DES	1674	familial atrial fibrillation	C3468561	Pathologic Function	0.3	0.503	0.759	phenotype
DES	1674	Atrial Fibrillation	C0004238	Disease or Syndrome	0.3	0.503	0.759	disease
DES	1674	Mammary Neoplasms, Experimental	C0024668	Experimental Model of Disease; Neoplastic Process	0.3	0.503	0.759	group
DES	1674	Carcinoma, Spindle-Cell	C0205697	Neoplastic Process	0.31	0.503	0.759	disease
DES	1674	Congenital diaphragmatic hernia	C0235833	Disease or Syndrome	0.3	0.503	0.759	disease
DES	1674	Carcinoma	C0007097	Neoplastic Process	0.3	0.503	0.759	group
DES	1674	Undifferentiated carcinoma	C0205698	Neoplastic Process	0.3	0.503	0.759	phenotype
DES	1674	Paroxysmal atrial fibrillation	C0235480	Disease or Syndrome	0.3	0.503	0.759	disease
DES	1674	Congenital hernia of foramen of Morgagni	C0265699	Congenital Abnormality	0.3	0.503	0.759	disease
DES	1674	Congenital hernia of foramen of Bochdalek	C0265700	Congenital Abnormality	0.3	0.503	0.759	disease
DES	1674	Hyperhomocysteinemia	C0598608	Disease or Syndrome	0.3	0.503	0.759	disease
DES	1674	Mammary Neoplasms, Human	C1257931	Neoplastic Process	0.3	0.503	0.759	group
DES	1674	Mammary Neoplasms	C1458155	Neoplastic Process	0.3	0.503	0.759	group
DES	1674	Bright Disease	C1704377	Disease or Syndrome	0.3	0.503	0.759	disease
DES	1674	Myofibrillar Myopathy	C2678065	Disease or Syndrome	0.5	0.503	0.759	disease
DES	1674	MUSCULAR DYSTROPHY, LIMB-GIRDLE, TYPE 2R	C3809137	Disease or Syndrome	0.6	0.503	0.759	disease
DES	1674	Scapuloperoneal Syndrome, Neurogenic, Kaeser Type	C1867005	Disease or Syndrome	0.7	0.503	0.759	disease
DES	1674	CARDIOMYOPATHY, DILATED, 1I	C1858154	Disease or Syndrome	0.8	0.503	0.759	disease
DES	1674	Conduction disorder of the heart	C0264886	Disease or Syndrome	0.3	0.503	0.759	group
DES	1674	Arthrogryposis	C0003886	Disease or Syndrome	0.3	0.503	0.759	disease
DES	1674	Palmoplantar Keratosis	C0022596	Disease or Syndrome	0.3	0.503	0.759	disease
DES	1674	Charcot-Marie-Tooth Disease	C0007959	Disease or Syndrome	0.3	0.503	0.759	disease
DES	1674	Congenital myopathy (disorder)	C0270960	Congenital Abnormality	0.33	0.503	0.759	group
DES	1674	Arrhythmogenic Right Ventricular Dysplasia	C0349788	Congenital Abnormality; Disease or Syndrome	0.45	0.503	0.759	disease
DES	1674	Erythrokeratoderma	C0432330	Congenital Abnormality	0.3	0.503	0.759	disease
DES	1674	Distal Muscular Dystrophies	C0751336	Disease or Syndrome	0.34	0.503	0.759	group
DES	1674	Cardiomyopathy, Dilated	C0007193	Disease or Syndrome	0.7	0.503	0.759	group
DES	1674	Hypertrophic Cardiomyopathy	C0007194	Disease or Syndrome	0.42	0.503	0.759	disease
DES	1674	Muscular Dystrophies, Limb-Girdle	C0686353	Disease or Syndrome	0.31	0.503	0.759	group
DES	1674	Familial dilated cardiomyopathy	C0340427	Disease or Syndrome	0.32	0.503	0.759	disease
DES	1674	MUSCULAR DYSTROPHY, LIMB-GIRDLE, TYPE 1E	C3148763	Disease or Syndrome	0.3	0.503	0.759	disease

Association with Drug

Protein Official Symbol	Human Entrez ID	drug_claim_primary_name	drug_name	drug_chembl_id	interaction_types
DES	1674	THROMBIN	THROMBIN	CHEMBL2108110	None
DES	1674	TPA	PHORBOL MYRISTATE ACETATE	CHEMBL279115	None