ALTITUDEOMICSDB

Myosin light chain 2

AltitudeomicsDB

Protein Official symbol	MYL2
Aliases	MYL2 MLC2
Chromosomal Location	12
Length	166
Uniprot ID	P10916
EC number	None
Protein family Information(Pfam)	PF13405;
PDB id	5TBY;
InterPro ID	IPR011992;IPR018247;IPR002048;
dbSNP	rs104894363 rs104894370 rs104894368 rs2428140 rs104894369 rs121913658 rs199474815

Protein Protein Interaction

Download Tab separated file

AltitudeomicsDB

Protein 1	Protein 2	Combine Score
TNNC2	TNNT3	0.9990000000000001
TNNI3	TNNC1	0.9990000000000001
TNNI2	TNNT3	0.9990000000000001
TNNI2	TNNC1	0.9990000000000001
NEB	TTN	0.9990000000000001
TNNI2	TNNC2	0.9990000000000001
TTN	TCAP	0.998
MYH6	TNNI1	0.998
GATA4	NKX2-5	0.998
TNNI3	TNNT2	0.998
MYH3	TNNI1	0.997
TPM1	ACTC1	0.997
ACTN2	MYH6	0.997
MYH7	MYL2	0.996
NEB	MYL1	0.996
MYL3	MYH7	0.996
MYH6	TPM1	0.996
MYH3	ACTN2	0.996
TNNI1	TNNC1	0.996
TNNI2	MYL1	0.995
TNNI1	TPM1	0.995
MYL1	TNNT3	0.995
ACTN2	TPM2	0.995
TTN	TNNC2	0.995
ACTN2	TPM1	0.995
TNNI1	TNNT2	0.995
TPM2	TNNI1	0.995
MYH6	TPM2	0.9940000000000001
ACTN2	TNNI1	0.9940000000000001
TNNT1	TNNI1	0.9940000000000001
MYH3	TPM2	0.9940000000000001
TTN	MYL1	0.9940000000000001
TNNI1	TNNT3	0.993
MEF2C	GATA4	0.993
TNNC2	MYL1	0.993
TNNT1	TNNI3	0.993
TNNI1	MYH7	0.993
TPM1	TNNT2	0.993
MYBPC3	TNNT2	0.992
MYH8	TPM1	0.992
MYBPC3	MYH6	0.992
NEB	TNNC2	0.992
PPP1R12A	ROCK1	0.992
PPP1R12A	ROCK2	0.992
MYLK	MYL2	0.992
MYL3	MYL2	0.991
MYH6	TNNT2	0.991
MEF2C	NKX2-5	0.991
MYH8	MYL1	0.991
MYH6	MYL2	0.991
TNNT1	TNNI2	0.991
ACTN2	MYH8	0.991
MYH6	MYL3	0.99
TTN	ACTN2	0.99
TNNI3	TNNT3	0.9890000000000001
TNNI2	TPM2	0.988
TPM2	TNNT3	0.988
TNNC2	TNNI3	0.988
ACTN2	TNNT2	0.987
ROCK1	ROCK2	0.987
VIM	DES	0.987
MYH6	TNNI3	0.987
TNNT2	TNNC1	0.987
TPM3	TPM1	0.986
MYBPC3	TNNI3	0.986
TPM1	TNNI3	0.986
TNNT1	TNNC1	0.986
MYBPC3	MYH7	0.986
TPM3	TMOD1	0.985
TPM1	MYL2	0.985
TNNT2	MYL2	0.985
MYL3	TNNI3	0.985
TNNT1	TPM1	0.985
MYH10	MYH9	0.9840000000000001
MYH6	MYL1	0.9840000000000001
MYL3	TNNT2	0.983
TNNI3	MYL2	0.983
MYBPC3	MYL2	0.983
MYH3	MYL1	0.983
NEB	TMOD4	0.983
TPM2	TPM1	0.983
NEB	TMOD1	0.983
MYH6	MYL4	0.982
MYL3	TNNI1	0.982
MYH8	MYL4	0.981
TNNT1	TPM3	0.981
MYBPC3	MYL3	0.981
MYH8	MYL3	0.981
TNNC2	TNNT2	0.981
MYH3	MYL4	0.981
TPM1	TNNT3	0.981
MYH6	MYH7	0.981
TTN	MYH6	0.981
MYBPC3	TPM1	0.98
TNNT1	TPM2	0.98
TNNI2	TNNT2	0.98
MYBPC2	TNNT3	0.98
MYH3	MYL3	0.98
MYH8	MYL2	0.98
TPM2	TPM3	0.9790000000000001
TPM3	ACTC1	0.9790000000000001
MYL3	TPM1	0.9790000000000001
NEB	TPM2	0.9790000000000001
MYH3	MYL2	0.978
TTN	ACTN3	0.978
TNNC2	TNNI1	0.978
ROCK2	MYL2	0.978
TNNT3	TNNC1	0.977
TPM1	TPM4	0.977
MYH3	TNNI2	0.977
TPM3	TNNT2	0.977
TPM1	TMOD1	0.976
MYH3	TNNT3	0.976
MYLK3	MYL2	0.976
TNNC2	TPM4	0.976
NKX2-5	MYL2	0.976
MYBPC1	TNNT3	0.976
TPM3	TNNT3	0.976
ACTN3	TNNT3	0.976
TTN	MYL2	0.976
TTN	MYL3	0.976
MYBPC1	TNNI2	0.976
ACTN2	TNNT3	0.975
PPP1R12A	MYLK	0.975
TPM2	TPM4	0.9740000000000001
TPM3	TNNI1	0.9740000000000001
ACTN2	TPM4	0.9740000000000001
TTN	TNNT2	0.9740000000000001
TNNI2	TPM1	0.9740000000000001
TNNI3	MYL1	0.9740000000000001
TPM3	TMOD3	0.9740000000000001
ACTN2	TPM3	0.9740000000000001
TTN	TNNI3	0.9740000000000001
MYL1	TNNT2	0.973
MYL1	MYH9	0.973
ACTN2	MYL2	0.972
TNNI1	MYL1	0.972
TPM2	MYL1	0.972
TNNC2	MYBPC2	0.972
TPM2	TNNT2	0.972
TNNI1	MYL4	0.972
TTN	DMD	0.972
TPM2	TNNC2	0.971
TTN	TNNT3	0.971
TPM3	MYL1	0.971
TNNC2	TPM1	0.971
MYL3	TNNI2	0.971
ACTN3	TNNC2	0.971
TPM4	TNNT3	0.971
TNNI2	TPM4	0.971
MYL4	TNNI3	0.97
MYH6	TNNC1	0.97
MYH6	ACTC1	0.97
TNNI2	TPM3	0.97
TPM3	TMOD2	0.97
TNNI1	MYL2	0.97
MYH8	TNNT3	0.97
TPM1	TMOD2	0.97
MYBPC3	TCAP	0.97
MYL3	TNNT3	0.97
TNNT1	TPM4	0.9690000000000001
ACTN2	TCAP	0.9690000000000001
NEB	TPM3	0.9690000000000001
ACTN3	MYBPC2	0.9690000000000001
TTN	MYL4	0.9690000000000001
TNNT1	MYL2	0.9690000000000001
ACTN3	TNNI2	0.9690000000000001
TPM1	MYL1	0.968
TTN	MYH8	0.968
TNNT1	MYL3	0.968
ACTN2	MYL3	0.968
MYH7	ACTC1	0.968
MYL4	TNNT2	0.968
MYL3	TCAP	0.968
MYH6	TCAP	0.968
ACTN2	TNNC2	0.968
TCAP	TNNT2	0.968
TPM4	TMOD3	0.968
TTN	MYH3	0.968
TPM4	TNNT2	0.9670000000000001
MYH6	TNNT3	0.9670000000000001
MYH3	TNNC2	0.9670000000000001
CDC42BPA	MYL2	0.9670000000000001
ACTC1	TNNT2	0.9670000000000001
TCAP	MYL2	0.966
ACTN2	MYH7	0.966
ACTN2	TNNI3	0.966
TNNI2	MYBPC2	0.966
TNNI2	MYL4	0.966
TNNT3	MYL2	0.966
TNNT1	TNNC2	0.966
TPM2	TMOD1	0.966
ACTN3	TPM2	0.966
MYLK	MYH9	0.966
PPP1R12A	MYL2	0.966
NEB	TPM1	0.966
TPM4	MYL1	0.966
TNNI3	TCAP	0.965
TNNT1	MYL4	0.965
MYL3	TPM2	0.965
ACTN3	TPM1	0.965
MYBPC1	MYL1	0.965
ACTN2	MYBPC3	0.9640000000000001
MYH6	TNNC2	0.9640000000000001
MYLK	MYL4	0.9640000000000001
ACTN3	TNNT2	0.9640000000000001
ACTN3	MYH6	0.9640000000000001
TNNT1	MYL1	0.9640000000000001
TNNI2	MYL2	0.9640000000000001
TTN	TPM1	0.9640000000000001
MYH8	TPM2	0.963
MYL3	MYLK	0.963
MYH10	MYLK	0.963
ROCK1	MYL2	0.963
TTN	MYBPC3	0.963
TPM2	TMOD3	0.963
MYH7	MYL4	0.963
ACTC1	MYL2	0.963
GATA4	MYL2	0.963
ACTN2	MYL1	0.963
TPM2	TNNI3	0.963
MYL3	MYH10	0.963
TNNI3	ACTC1	0.9620000000000001
MYH8	TNNC2	0.9620000000000001
NEB	TNNT3	0.9620000000000001
MYH7	MYL1	0.9620000000000001
NEB	TCAP	0.9620000000000001
TPM4	TMOD1	0.9620000000000001
MYH3	TNNT2	0.9620000000000001
MYH8	TNNI3	0.9620000000000001
MYL3	TPM3	0.9620000000000001
MYH6	TPM3	0.961
TPM3	TNNI3	0.961
TNNT1	MYH6	0.961
MYL3	ACTC1	0.961
MYH6	DMD	0.961
NEB	TNNT1	0.961
MYL3	MYH9	0.96
MYH3	TNNI3	0.96
TTN	TNNC1	0.96
ACTN3	MYH8	0.96
ROCK1	MYH9	0.96
TNNT1	TTN	0.96
TPM1	TMOD3	0.96
MYL4	TNNT3	0.9590000000000001
TPM2	MYL2	0.9590000000000001
MYH8	TNNI1	0.9590000000000001
TPM3	MYL2	0.9590000000000001
MYH14	MYL3	0.9590000000000001
ACTN3	TPM4	0.9590000000000001
ACTN3	MYL1	0.9590000000000001
TPM1	TCAP	0.9590000000000001
TTN	TNNI1	0.9590000000000001
TPM2	MYL4	0.9590000000000001
TNNI1	TPM4	0.9590000000000001
MYH6	TNNI2	0.9590000000000001
MYBPC1	TNNI1	0.9590000000000001
PPP1R12B	MYLK	0.958
ACTN3	TPM3	0.958
MYH6	TPM4	0.958
TPM4	TNNI3	0.958
NEB	DES	0.958
MEF2C	MYL2	0.9570000000000001
NEB	MYH8	0.9570000000000001
TNNC1	MYL2	0.9570000000000001
MYL3	TPM4	0.9570000000000001
NEB	MYH6	0.9570000000000001
MYH8	TNNT2	0.9570000000000001
MYH8	TNNI2	0.9570000000000001
TPM4	MYL2	0.956
TPM2	TMOD2	0.956
NEB	DMD	0.956
TPM3	MYL4	0.956
MYBPC3	TPM3	0.956
MYL4	TPM4	0.956
MYH3	ACTN3	0.955
TPM2	TMOD4	0.955
TPM1	MYL4	0.955
TPM4	TMOD2	0.955
TPM1	TNNC1	0.955
PPP1R12B	ROCK1	0.955
TTN	TNNI2	0.9540000000000001
MYBPC1	MYL3	0.9540000000000001
NEB	MYH3	0.9540000000000001
DMD	TCAP	0.9540000000000001
TTN	MYBPC1	0.9540000000000001
TPM3	TMOD4	0.9540000000000001
TTN	TPM2	0.9540000000000001
TNNC2	TPM3	0.9540000000000001
MYH8	MYBPC2	0.9540000000000001
MYH10	MYL1	0.9540000000000001
NEB	ACTN2	0.9540000000000001
MYH3	TPM1	0.953
MYH8	TPM4	0.9520000000000001
MYH14	MYLK	0.9520000000000001
NEB	MYBPC2	0.9520000000000001
MYBPC1	TNNC2	0.9520000000000001
PPP1R12B	PPP1R12A	0.9520000000000001
TNNT1	ACTN2	0.9520000000000001
MYH8	TPM3	0.951
MYH3	DMD	0.951
NEB	ACTN3	0.951
MYBPC3	MYL4	0.951
MYH3	TPM4	0.95
TNNT1	MYBPC1	0.95
ACTN2	TNNI2	0.95
PPP1R12B	ROCK2	0.95
MYH3	TPM3	0.95
TNNI1	MYBPC2	0.95
TTN	DES	0.95
TPM4	TMOD4	0.9490000000000001
MYBPC1	TPM2	0.9490000000000001
TTN	TPM3	0.9490000000000001
MYH8	DMD	0.948
NEB	TMOD3	0.948
TPM1	TMOD4	0.948
TNNT1	MYH8	0.948
TNNT1	MYH3	0.948
TNNT1	ACTN3	0.9470000000000001
ACTN2	MYL4	0.9470000000000001
MYBPC1	MYH8	0.9470000000000001
TPM3	TNNC1	0.9470000000000001
TPM2	TNNC1	0.9470000000000001
ACTN2	DES	0.946
NEB	TPM4	0.946
MYLK	TPM1	0.946
TPM2	DMD	0.946
ACTN2	TNNC1	0.946
DES	TCAP	0.946
DMD	TPM1	0.946
MYBPC2	MYL1	0.946
MYH6	MYBPC2	0.946
MYH14	MYL1	0.946
ACTN3	MYL2	0.946
TPM3	DMD	0.946
TNNT1	MYBPC2	0.945
TTN	TPM4	0.945
MYBPC3	TNNI1	0.945
MYBPC3	TNNC1	0.945
MYBPC3	DES	0.9440000000000001
ACTN3	MYL3	0.9440000000000001
TCAP	MYL1	0.9440000000000001
TNNT1	MYBPC3	0.9440000000000001
TPM2	MYH7	0.943
MYH3	MYBPC1	0.943
TTN	TMOD1	0.943
NFATC1	GATA4	0.943
MYBPC1	TNNT2	0.943
ACTN3	TMOD4	0.9420000000000001
MYL3	TNNC1	0.9420000000000001
PPP1R12A	MYH9	0.9420000000000001
MYL3	DMD	0.9420000000000001
NEB	MYBPC1	0.9420000000000001
NEB	TNNI2	0.941
MYBPC3	TNNT3	0.941
TPM2	MYLK	0.941
NEB	MYL2	0.941
ACTN2	MYBPC2	0.941
NEB	MYL3	0.94
ACTN3	TNNI1	0.94
MYBPC2	TNNC1	0.94
DES	TPM1	0.94
DMD	TNNI3	0.94
DES	TNNI3	0.94
CIT	MYL2	0.94
MYBPC3	MYL1	0.94
MYL4	TCAP	0.94
NEB	MYL4	0.9390000000000001
TNNC2	TCAP	0.9390000000000001
MYBPC1	TMOD4	0.9390000000000001
DMD	TNNT2	0.9390000000000001
DES	TNNT2	0.9390000000000001
ACTN2	ACTN3	0.9390000000000001
ACTN2	MYBPC1	0.9390000000000001
MYH8	TNNC1	0.9390000000000001
TPM2	MYBPC2	0.938
MYL1	MYL2	0.938
ACTN3	MYL4	0.938
MYL3	MYBPC2	0.938
TPM3	TPM4	0.938
MYBPC2	MYL2	0.938
DMD	MYL1	0.938
TMOD4	TNNT3	0.938
DES	TNNC2	0.938
MYBPC1	MYH6	0.937
MYBPC1	MYL4	0.937
TPM3	MYLK	0.937
DES	MYL1	0.937
DMD	TPM4	0.937
MYBPC2	TNNT2	0.937
MYH10	ACTC1	0.9359999999999999
TNNT1	TMOD4	0.9359999999999999
ACTN3	TNNC1	0.9359999999999999
MYLK	TPM4	0.9359999999999999
TNNI2	TMOD1	0.9359999999999999
MYBPC3	TMOD1	0.9359999999999999
MYH3	TCAP	0.935
PPP1R12B	MYL2	0.935
TCAP	TMOD4	0.935
ACTN3	TCAP	0.935
MYBPC1	DMD	0.935
PPP1R12B	MYH9	0.935
NEB	TNNT2	0.935
MYH6	DES	0.935
MYBPC1	MYL2	0.935
TTN	TMOD4	0.935
TPM1	MYBPC2	0.935
MYBPC3	TNNI2	0.935
MYL1	TMOD4	0.935
TNNI2	TCAP	0.934
DMD	MYL2	0.934
TPM4	TNNC1	0.934
TNNT3	TMOD1	0.934
MYH3	MYBPC2	0.934
MYBPC1	TNNI3	0.9329999999999999
NEB	TNNI1	0.9329999999999999
TCAP	TNNT3	0.932
MYH3	TNNC1	0.932
PPP1R12A	MYH10	0.932
TNNC2	TNNC1	0.932
ACTN3	TMOD1	0.9309999999999999
DMD	TNNT3	0.9309999999999999
MYBPC1	TNNC1	0.9309999999999999
TPM3	TCAP	0.93
NEB	MYBPC3	0.93
NFATC1	MEF2C	0.93
MYBPC3	MYH8	0.93
ACTN3	MYBPC1	0.93
TCAP	TNNC1	0.93
MYBPC3	DMD	0.93
NEB	TMOD2	0.93
TNNI2	TMOD4	0.93
TMOD4	TNNC1	0.93
TMOD1	TNNT2	0.93
DMD	TNNI1	0.929
TNNI1	TCAP	0.929
NEB	TNNI3	0.929
MYL3	TMOD4	0.9279999999999999
DMD	MYL4	0.9279999999999999
MYH8	TCAP	0.9279999999999999
VIM	TPM2	0.9279999999999999
NFATC1	MYL2	0.9279999999999999
NFATC1	NKX2-5	0.9279999999999999
MYLK	MYL1	0.9279999999999999
TPM3	MYBPC2	0.927
MYBPC1	TPM3	0.927
MYBPC1	TPM1	0.927
ROCK1	MYH10	0.927
DMD	TMOD1	0.9259999999999999
ACTN2	DMD	0.9259999999999999
CIT	MYH10	0.9259999999999999
TNNC2	TMOD4	0.9259999999999999
MYL1	TNNC1	0.9259999999999999
MYL3	DES	0.9259999999999999
TNNT1	DMD	0.925
MYH3	TMOD1	0.925
MYBPC2	TMOD4	0.925
VIM	TPM4	0.925
ROCK2	MYH9	0.925
TTN	MYBPC2	0.925
MYL4	TMOD1	0.925
VIM	TPM1	0.925
MYH10	ROCK2	0.924
ACTN2	TMOD4	0.924
DES	TNNC1	0.924
PPP1R12B	MYH10	0.924
MYH6	TMOD1	0.924
TPM2	TCAP	0.924
TNNI1	TMOD1	0.924
TNNT1	TMOD1	0.924
TCAP	TMOD1	0.924
MYH3	MYBPC3	0.9229999999999999
MYL4	MYL2	0.9229999999999999
TMOD4	MYL2	0.9229999999999999
TNNT1	TCAP	0.9229999999999999
TTN	VIM	0.9229999999999999
MYH8	TMOD4	0.922
ACTN3	DMD	0.922
MYL3	TMOD1	0.922
ACTN3	TNNI3	0.922
MYL4	TNNC1	0.922
TNNI2	DMD	0.922
ACTN3	TMOD3	0.9209999999999999
DES	DMD	0.9209999999999999
TNNT1	DES	0.9209999999999999
MYBPC3	TPM2	0.9209999999999999
TNNC2	DMD	0.9209999999999999
TNNI3	TMOD1	0.9209999999999999
MYH14	MYH9	0.9209999999999999
MYH6	TMOD4	0.92
TNNT1	TNNT2	0.92
MYBPC2	TCAP	0.92
ACTN2	TMOD1	0.92
MYL3	TNNC2	0.92
TNNC2	MYL2	0.92
MYL3	MYL1	0.92
DES	MYL2	0.919
MYBPC2	TNNI3	0.919
VIM	TPM3	0.919
ACTN2	TMOD2	0.919
TNNI2	TMOD3	0.919
MYH10	MYL2	0.919
MYBPC3	TPM4	0.919
MYL4	TMOD4	0.919
CIT	MYH9	0.919
DMD	TNNC1	0.9179999999999999
MYBPC3	ACTN3	0.9179999999999999
NEB	VIM	0.9179999999999999
VIM	MYH6	0.9179999999999999
MYH6	MYH10	0.9179999999999999
TTN	TMOD3	0.9179999999999999
MYBPC3	TNNC2	0.9179999999999999
MYH8	TMOD1	0.917
DMD	TMOD3	0.917
MYBPC2	TMOD1	0.917
TMOD1	TNNC1	0.917
MYH10	MYH7	0.917
MYBPC2	MYL4	0.9159999999999999
ACTN3	TMOD2	0.9159999999999999
ACTN2	TMOD3	0.9159999999999999
VIM	TNNC2	0.9159999999999999
MYL1	TMOD1	0.9159999999999999
MYH14	MYH10	0.9159999999999999
TPM4	TCAP	0.9159999999999999
MYH14	MYL2	0.9159999999999999
DMD	MYBPC2	0.915
TMOD1	MYL2	0.915
TNNT1	VIM	0.915
VIM	TNNT2	0.915
DMD	TMOD4	0.915
MYH8	MYH10	0.915
VIM	TNNI2	0.914
DES	TNNT3	0.914
DES	TNNI1	0.914
MYBPC1	MYBPC2	0.9129999999999999
TPM2	DES	0.9129999999999999
VIM	ACTN2	0.9129999999999999
TMOD3	MYL1	0.9129999999999999
TNNT3	TMOD2	0.9129999999999999
TMOD3	TNNT3	0.9129999999999999
MYH14	PPP1R12A	0.9129999999999999
MYH3	TMOD4	0.9129999999999999
TNNI2	TMOD2	0.9129999999999999
TMOD4	TNNT2	0.9129999999999999
TMOD2	TNNT2	0.9129999999999999
PPP1R12B	MYH14	0.9129999999999999
MYBPC2	TPM4	0.9129999999999999
TMOD3	TNNT2	0.9129999999999999
VIM	MYL1	0.912
TNNI1	TMOD2	0.912
MYBPC3	TMOD3	0.912
TNNI3	TMOD3	0.912
MYBPC3	TMOD2	0.912
ACTN3	DES	0.912
VIM	ACTN3	0.912
TNNI1	TMOD3	0.912
TNNI3	TMOD2	0.912
NEB	TNNC1	0.9109999999999999
TNNI2	TNNI1	0.9109999999999999
TTN	TMOD2	0.9109999999999999
DMD	TMOD2	0.9109999999999999
VIM	TNNT3	0.9109999999999999
TNNC2	MYL4	0.91
TNNI2	TNNI3	0.91
MYL4	MYL1	0.91
TNNT1	TMOD3	0.91
MYL4	ACTC1	0.91
MYH14	CIT	0.91
VIM	TNNI3	0.91
MYH7	TNNT2	0.91
DES	TPM3	0.909
VIM	MYBPC3	0.909
DES	TPM4	0.909
MYH14	ROCK2	0.909
DES	TMOD1	0.909
MYH6	MYH8	0.9079999999999999
MYH3	TMOD3	0.9079999999999999
TNNI3	TMOD4	0.9079999999999999
VIM	MYL4	0.9079999999999999
VIM	MYL2	0.9079999999999999
TNNT1	TMOD2	0.9079999999999999
MYH3	TMOD2	0.9079999999999999
MYH8	DES	0.9079999999999999
MYH8	MYH7	0.907
TNNI1	TMOD4	0.907
MYBPC3	TMOD4	0.907
VIM	DMD	0.907
MYH6	TMOD2	0.907
TNNT1	TNNT3	0.907
MYH6	TMOD3	0.907
MYL1	TMOD2	0.907
MYH14	ROCK1	0.907
MYH8	TMOD2	0.907
MYH8	TMOD3	0.907
TNNI2	DES	0.907
MYBPC1	DES	0.9059999999999999
MYBPC1	TMOD2	0.9059999999999999
VIM	TMOD4	0.9059999999999999
MYH14	MYH6	0.9059999999999999
MYH3	DES	0.9059999999999999
TMOD2	TNNC1	0.9059999999999999
MYBPC1	TCAP	0.9059999999999999
VIM	TNNI1	0.9059999999999999
TTN	MYH7	0.9059999999999999
DES	MYBPC2	0.905
MYL3	TMOD3	0.905
TMOD3	TNNC1	0.905
VIM	TMOD1	0.905
MYH3	MYH8	0.905
MYBPC1	TPM4	0.905
MYBPC3	MYBPC1	0.905
TNNT3	TNNT2	0.905
MYH14	MYH7	0.905
TMOD4	TMOD1	0.905
MYH3	VIM	0.904
MYBPC1	TMOD1	0.904
VIM	MYL3	0.904
VIM	TCAP	0.904
MYBPC3	MYBPC2	0.904
VIM	TNNC1	0.904
DES	TMOD4	0.904
MYH14	MYH8	0.903
TNNI1	TNNI3	0.903
TMOD3	TMOD4	0.903
TMOD4	TMOD2	0.903
MYL3	TMOD2	0.903
MYL3	MYL4	0.903
MYBPC1	TMOD3	0.903
MYL2	MYH9	0.903
VIM	TMOD3	0.903
MYL4	TMOD3	0.903
VIM	MYH8	0.903
DES	TMOD2	0.903
VIM	TMOD2	0.903
DES	TMOD3	0.903
VIM	MYBPC1	0.903
DES	MYL4	0.903
MYH3	MYH6	0.903
MYL4	TMOD2	0.902
MYH6	MYH9	0.902
TMOD3	MYL2	0.902
TMOD3	TMOD1	0.902
TMOD2	MYL2	0.902
TCAP	TMOD3	0.902
TNNC2	TMOD1	0.902
TCAP	TMOD2	0.902
TMOD1	TMOD2	0.902
MYBPC2	TMOD3	0.902
MYBPC2	TMOD2	0.902
VIM	MYBPC2	0.902
MYH7	MYH9	0.9009999999999999
TMOD3	TMOD2	0.9009999999999999
TNNC2	TMOD3	0.9
MYH8	MYH9	0.9
TNNC2	TMOD2	0.9

Gene Ontology Semantic Similarity

Download Tab separated file

#	7125 (TNNC2)	7137 (TNNI3)	7136 (TNNI2)	4703 (NEB)	7273 (TTN)	4624 (MYH6)	7168 (TPM1)	88 (ACTN2)	4621 (MYH3)	7135 (TNNI1)	4625 (MYH7)	4634 (MYL3)	7169 (TPM2)	4632 (MYL1)	7138 (TNNT1)	4607 (MYBPC3)	4638 (MYLK)	4626 (MYH8)	7431 (VIM)	7139 (TNNT2)	7170 (TPM3)	4606 (MYBPC2)	7140 (TNNT3)	4604 (MYBPC1)	89 (ACTN3)	7171 (TPM4)	4635 (MYL4)	8557 (TCAP)	70 (ACTC1)	7134 (TNNC1)	1756 (DMD)	1674 (DES)	7111 (TMOD1)	29766 (TMOD3)	4633 (MYL2)
7125 (TNNC2)	1.00	0.81	0.82	0.66	0.71	0.31	0.78	0.67	0.57	1.00	0.53	0.55	0.72	0.26	0.73	0.66	0.64	0.45	0.67	0.80	0.74	0.70	0.73	0.70	0.66	0.87	0.69	0.69	0.46	0.90	0.74	0.73	1.00	0.49	0.80
7137 (TNNI3)	0.81	1.00	0.82	0.66	0.68	0.40	0.76	0.71	0.55	1.00	0.56	0.53	0.67	0.26	0.70	0.67	0.64	0.46	0.67	0.80	0.72	0.68	0.74	0.69	0.66	0.70	0.62	0.69	0.49	0.79	0.72	0.73	1.00	0.49	0.67
7136 (TNNI2)	0.82	0.82	1.00	0.73	0.62	0.31	0.77	0.69	0.50	1.00	0.53	0.61	0.73	0.26	0.82	0.63	0.70	0.40	0.70	0.85	0.70	0.65	0.73	0.66	0.70	0.68	0.69	0.73	0.51	0.79	0.77	0.80	1.00	0.49	0.70
4703 (NEB)	0.66	0.66	0.73	1.00	0.68	0.26	0.83	0.73	0.39	1.00	0.44	0.74	0.78	1.00	0.74	0.72	0.60	0.47	0.72	0.72	0.83	0.81	0.59	0.79	0.85	0.81	0.47	0.83	0.37	0.66	0.82	0.80	0.69	0.49	0.79
7273 (TTN)	0.71	0.68	0.62	0.68	1.00	0.38	0.74	0.70	0.51	1.00	0.52	0.51	0.61	1.00	0.60	0.77	0.69	0.48	0.66	0.63	0.72	0.79	0.54	0.79	0.68	0.77	0.46	0.69	0.42	0.71	0.70	0.70	0.72	0.49	0.72
4624 (MYH6)	0.31	0.40	0.31	0.26	0.38	1.00	0.29	0.34	0.79	0.60	0.82	0.20	0.22	0.16	0.30	0.29	0.26	0.67	0.33	0.33	0.32	0.26	0.51	0.27	0.30	0.26	0.19	0.33	0.57	0.32	0.33	0.31	0.40	0.28	0.27
7168 (TPM1)	0.78	0.76	0.77	0.83	0.74	0.29	1.00	0.77	0.53	1.00	0.49	0.76	0.90	1.00	0.68	0.80	0.58	0.61	0.76	0.78	0.86	0.85	0.69	0.85	0.78	0.85	0.66	0.80	0.47	0.73	0.86	0.89	1.00	0.49	0.80
88 (ACTN2)	0.67	0.71	0.69	0.73	0.70	0.34	0.77	1.00	0.49	1.00	0.58	0.54	0.61	1.00	0.68	0.76	0.63	0.48	0.71	0.71	0.72	0.72	0.60	0.75	0.83	0.71	0.48	0.83	0.47	0.71	0.74	0.76	0.84	0.49	0.71
4621 (MYH3)	0.57	0.55	0.50	0.39	0.51	0.79	0.53	0.49	1.00	0.82	0.77	0.34	0.48	0.21	0.44	0.48	0.37	0.76	0.47	0.51	0.54	0.48	0.62	0.49	0.44	0.50	0.46	0.48	0.55	0.55	0.49	0.46	0.72	0.40	0.42
7135 (TNNI1)	1.00	1.00	1.00	1.00	1.00	0.60	1.00	1.00	0.82	1.00	1.00	0.60	0.69	0.26	1.00	1.00	1.00	0.60	1.00	1.00	1.00	1.00	0.82	1.00	1.00	1.00	0.60	1.00	0.69	1.00	1.00	1.00	0.69	0.49	1.00
4625 (MYH7)	0.53	0.56	0.53	0.44	0.52	0.82	0.49	0.58	0.77	1.00	1.00	0.33	0.36	0.26	0.51	0.49	0.41	0.64	0.56	0.57	0.49	0.44	0.73	0.46	0.51	0.44	0.34	0.58	0.71	0.55	0.55	0.53	0.69	0.49	0.47
4634 (MYL3)	0.55	0.53	0.61	0.74	0.51	0.20	0.76	0.54	0.34	0.60	0.33	1.00	0.80	1.00	0.51	0.64	0.41	0.49	0.48	0.61	0.69	0.67	0.53	0.66	0.60	0.65	0.80	0.60	0.39	0.48	0.70	0.62	0.86	0.28	0.80
7169 (TPM2)	0.72	0.67	0.73	0.78	0.61	0.22	0.90	0.61	0.48	0.69	0.36	0.80	1.00	1.00	0.58	0.71	0.45	0.58	0.55	0.72	0.84	0.82	0.64	0.80	0.68	0.81	0.73	0.66	0.39	0.63	0.77	0.68	1.00	0.33	0.73
4632 (MYL1)	0.26	0.26	0.26	1.00	1.00	0.16	1.00	1.00	0.21	0.26	0.26	1.00	1.00	1.00	0.26	1.00	0.26	1.00	0.59	0.26	1.00	1.00	0.21	1.00	1.00	1.00	0.16	1.00	0.18	0.26	1.00	0.59	0.18	0.13	1.00
7138 (TNNT1)	0.73	0.70	0.82	0.74	0.60	0.30	0.68	0.68	0.44	1.00	0.51	0.51	0.58	0.26	1.00	0.60	0.70	0.35	0.70	0.87	0.66	0.61	0.73	0.62	0.70	0.64	0.56	0.73	0.47	0.71	0.71	0.79	0.70	0.49	0.65
4607 (MYBPC3)	0.66	0.67	0.63	0.72	0.77	0.29	0.80	0.76	0.48	1.00	0.49	0.64	0.71	1.00	0.60	1.00	0.55	0.58	0.68	0.64	0.76	0.86	0.57	0.89	0.72	0.75	0.57	0.75	0.51	0.67	0.77	0.75	0.72	0.49	0.75
4638 (MYLK)	0.64	0.64	0.70	0.60	0.69	0.26	0.58	0.63	0.37	1.00	0.41	0.41	0.45	0.26	0.70	0.55	1.00	0.29	0.64	0.70	0.58	0.53	0.57	0.55	0.61	0.54	0.45	0.67	0.35	0.64	0.64	0.67	0.69	0.49	0.56
4626 (MYH8)	0.45	0.46	0.40	0.47	0.48	0.67	0.61	0.48	0.76	0.60	0.64	0.49	0.58	1.00	0.35	0.58	0.29	1.00	0.41	0.44	0.59	0.56	0.53	0.57	0.47	0.54	0.42	0.48	0.73	0.45	0.55	0.44	0.72	0.28	0.50
7431 (VIM)	0.67	0.67	0.70	0.72	0.66	0.33	0.76	0.71	0.47	1.00	0.56	0.48	0.55	0.59	0.70	0.68	0.64	0.41	1.00	0.70	0.69	0.69	0.57	0.69	0.72	0.68	0.46	0.72	0.42	0.68	0.73	0.84	0.69	0.49	0.68
7139 (TNNT2)	0.80	0.80	0.85	0.72	0.63	0.33	0.78	0.71	0.51	1.00	0.57	0.61	0.72	0.26	0.87	0.64	0.70	0.44	0.70	1.00	0.70	0.66	0.89	0.67	0.69	0.68	0.67	0.72	0.56	0.78	0.76	0.81	1.00	0.49	0.70
7170 (TPM3)	0.74	0.72	0.70	0.83	0.72	0.32	0.86	0.72	0.54	1.00	0.49	0.69	0.84	1.00	0.66	0.76	0.58	0.59	0.69	0.70	1.00	0.85	0.60	0.83	0.78	0.85	0.59	0.77	0.40	0.72	0.78	0.74	0.72	0.49	0.74
4606 (MYBPC2)	0.70	0.68	0.65	0.81	0.79	0.26	0.85	0.72	0.48	1.00	0.44	0.67	0.82	1.00	0.61	0.86	0.53	0.56	0.69	0.66	0.85	1.00	0.57	0.97	0.76	0.83	0.56	0.76	0.38	0.69	0.77	0.74	0.72	0.49	0.73
7140 (TNNT3)	0.73	0.74	0.73	0.59	0.54	0.51	0.69	0.60	0.62	0.82	0.73	0.53	0.64	0.21	0.73	0.57	0.57	0.53	0.57	0.89	0.60	0.57	1.00	0.58	0.57	0.58	0.59	0.61	0.64	0.71	0.66	0.68	1.00	0.40	0.60
4604 (MYBPC1)	0.70	0.69	0.66	0.79	0.79	0.27	0.85	0.75	0.49	1.00	0.46	0.66	0.80	1.00	0.62	0.89	0.55	0.57	0.69	0.67	0.83	0.97	0.58	1.00	0.76	0.82	0.56	0.80	0.42	0.69	0.77	0.75	0.72	0.49	0.73
89 (ACTN3)	0.66	0.66	0.70	0.85	0.68	0.30	0.78	0.83	0.44	1.00	0.51	0.60	0.68	1.00	0.70	0.72	0.61	0.47	0.72	0.69	0.78	0.76	0.57	0.76	1.00	0.76	0.47	0.81	0.40	0.73	0.78	0.76	0.69	0.49	0.75
7171 (TPM4)	0.87	0.70	0.68	0.81	0.77	0.26	0.85	0.71	0.50	1.00	0.44	0.65	0.81	1.00	0.64	0.75	0.54	0.54	0.68	0.68	0.85	0.83	0.58	0.82	0.76	1.00	0.58	0.76	0.37	0.82	0.77	0.72	0.72	0.49	0.87
4635 (MYL4)	0.69	0.62	0.69	0.47	0.46	0.19	0.66	0.48	0.46	0.60	0.34	0.80	0.73	0.16	0.56	0.57	0.45	0.42	0.46	0.67	0.59	0.56	0.59	0.56	0.47	0.58	1.00	0.48	0.44	0.60	0.59	0.56	0.86	0.28	0.65
8557 (TCAP)	0.69	0.69	0.73	0.83	0.69	0.33	0.80	0.83	0.48	1.00	0.58	0.60	0.66	1.00	0.73	0.75	0.67	0.48	0.72	0.72	0.77	0.76	0.61	0.80	0.81	0.76	0.48	1.00	0.48	0.69	0.78	0.79	0.70	0.49	0.76
70 (ACTC1)	0.46	0.49	0.51	0.37	0.42	0.57	0.47	0.47	0.55	0.69	0.71	0.39	0.39	0.18	0.47	0.51	0.35	0.73	0.42	0.56	0.40	0.38	0.64	0.42	0.40	0.37	0.44	0.48	1.00	0.48	0.55	0.48	0.70	0.33	0.46
7134 (TNNC1)	0.90	0.79	0.79	0.66	0.71	0.32	0.73	0.71	0.55	1.00	0.55	0.48	0.63	0.26	0.71	0.67	0.64	0.45	0.68	0.78	0.72	0.69	0.71	0.69	0.73	0.82	0.60	0.69	0.48	1.00	0.69	0.74	0.72	0.49	0.74
1756 (DMD)	0.74	0.72	0.77	0.82	0.70	0.33	0.86	0.74	0.49	1.00	0.55	0.70	0.77	1.00	0.71	0.77	0.64	0.55	0.73	0.76	0.78	0.77	0.66	0.77	0.78	0.77	0.59	0.78	0.55	0.69	1.00	0.79	1.00	0.49	0.82
1674 (DES)	0.73	0.73	0.80	0.80	0.70	0.31	0.89	0.76	0.46	1.00	0.53	0.62	0.68	0.59	0.79	0.75	0.67	0.44	0.84	0.81	0.74	0.74	0.68	0.75	0.76	0.72	0.56	0.79	0.48	0.74	0.79	1.00	0.84	0.49	0.74
7111 (TMOD1)	1.00	1.00	1.00	0.69	0.72	0.40	1.00	0.84	0.72	0.69	0.69	0.86	1.00	0.18	0.70	0.72	0.69	0.72	0.69	1.00	0.72	0.72	1.00	0.72	0.69	0.72	0.86	0.70	0.70	0.72	1.00	0.84	1.00	0.33	0.86
29766 (TMOD3)	0.49	0.49	0.49	0.49	0.49	0.28	0.49	0.49	0.40	0.49	0.49	0.28	0.33	0.13	0.49	0.49	0.49	0.28	0.49	0.49	0.49	0.49	0.40	0.49	0.49	0.49	0.28	0.49	0.33	0.49	0.49	0.49	0.33	1.00	0.49
4633 (MYL2)	0.80	0.67	0.70	0.79	0.72	0.27	0.80	0.71	0.42	1.00	0.47	0.80	0.73	1.00	0.65	0.75	0.56	0.50	0.68	0.70	0.74	0.73	0.60	0.73	0.75	0.87	0.65	0.76	0.46	0.74	0.82	0.74	0.86	0.49	1.00

Association with High Altitude

Protein Official symbol	Source Organism	Tissue of Expression	Level of hypoxia	Altitude	Duration of experiment	Level of expression	Fold change	Experiment details	geographical location	ethnicity of the patients	Control group	Control (Fold change)	Reference (PMID)
MYL2	Human	Blood	-	3250 m	4 day	upregulated	1.5014	Microarray	Himalayas	Indians	1	Sea level healthy individuals	24465776

Association with TF

TF	TF Entrez	Gene	Gene Entrez	Type	PMID	Database
USF1	7391	MYL2	4633	distal	22955619	TRANSFAC
BCL3	602	MYL2	4633	distal	22955619	TRANSFAC
MAX	4149	MYL2	4633	distal	22955619	TRANSFAC
POU5F1	5460	MYL2	4633	distal	22955619	TRANSFAC
TCF12	6938	MYL2	4633	distal	22955619	TRANSFAC
PBX3	5090	MYL2	4633	distal	22955619	TRANSFAC
NFKB1	4790	MYL2	4633	distal	22955619	TRANSFAC
TBP	6908	MYL2	4633	distal	22955619	TRANSFAC
CHD2	1106	MYL2	4633	distal	22955619	TRANSFAC
POU2F2	5452	MYL2	4633	distal	22955619	TRANSFAC
TAF1	6872	MYL2	4633	distal	22955619	TRANSFAC
BATF	10538	MYL2	4633	distal	22955619	TRANSFAC
USF2	7392	MYL2	4633	distal	22955619	TRANSFAC
E2F6	1876	MYL2	4633	distal	22955619	TRANSFAC
EGR1	1958	MYL2	4633	distal	22955619	TRANSFAC
PAX5	5079	MYL2	4633	distal	22955619	TRANSFAC
SP1	6667	MYL2	4633	distal	22955619	TRANSFAC
YY1	7528	MYL2	4633	distal	22955619	TRANSFAC
EBF1	1879	MYL2	4633	distal	22955619	TRANSFAC
IRF4	3662	MYL2	4633	distal	22955619	TRANSFAC
CTCF	10664	MYL2	4633	distal	22955619	TRANSFAC
EP300	2033	MYL2	4633	distal	22955619	TRANSFAC
MEF2C	4208	MYL2	4633	distal	22955619	TRANSFAC
RXRA	6256	MYL2	4633	distal	22955619	TRANSFAC
NANOG	79923	MYL2	4633	distal	22955619	TRANSFAC
SRF	6722	MYL2	4633	distal	22955619	TRANSFAC
ZEB1	6935	MYL2	4633	distal	22955619	TRANSFAC
SMC3	9126	MYL2	4633	distal	22955619	TRANSFAC
MEF2A	4205	MYL2	4633	distal	22955619	TRANSFAC
BCL11A	53335	MYL2	4633	distal	22955619	TRANSFAC
HDAC2	3066	MYL2	4633	distal	22955619	TRANSFAC
RAD21	5885	MYL2	4633	distal	22955619	TRANSFAC
SPI1	6688	MYL2	4633	distal	22955619	TRANSFAC

Association with miRNA

miRTarBase ID	miRNA	Species (miRNA)	Protein Official Symbol	Human Entrez ID	Species (Target Gene)	Experiments	Support Type	References (PMID)
MIRT048671	hsa-miR-99a-5p	Homo sapiens	MYL2	4633	Homo sapiens	CLASH	Functional MTI (Weak)	23622248

Gene Ontology

ID	GO ID	GO Term	GO Type
4633	GO:0002026	regulation of the force of heart contraction	GOTERM_BP_DIRECT
4633	GO:0060047	heart contraction	GOTERM_BP_DIRECT
4633	GO:0032036	N-terminal myristoylation domain binding	GOTERM_MF_DIRECT
4633	GO:0006942	regulation of striated muscle contraction	GOTERM_BP_DIRECT
4633	GO:0030049	muscle filament sliding	GOTERM_BP_DIRECT
4633	GO:0098735	positive regulation of the force of heart contraction	GOTERM_BP_DIRECT
4633	GO:0015629	actin cytoskeleton	GOTERM_CC_DIRECT
4633	GO:0005509	calcium ion binding	GOTERM_MF_DIRECT
4633	GO:0016459	myosin complex	GOTERM_CC_DIRECT
4633	GO:0042694	muscle cell fate specification	GOTERM_BP_DIRECT
4633	GO:0009791	post-embryonic development	GOTERM_BP_DIRECT
4633	GO:0008307	lipid binding	GOTERM_MF_DIRECT
4633	GO:0030017	sarcomere	GOTERM_CC_DIRECT
4633	GO:0055003	cardiac myofibril assembly	GOTERM_BP_DIRECT
4633	GO:0048747	muscle fiber development	GOTERM_BP_DIRECT
4633	GO:0055010	ventricular cardiac muscle tissue morphogenesis	GOTERM_BP_DIRECT
4633	GO:0060048	cardiac muscle contraction	GOTERM_BP_DIRECT
4633	GO:0005829	cytosol	GOTERM_CC_DIRECT
4633	GO:0005856	cytoskeleton	GOTERM_CC_DIRECT
4633	GO:0003007	heart morphogenesis	GOTERM_BP_DIRECT
4633	GO:0003785	actin binding	GOTERM_MF_DIRECT
4633	GO:0005515	protein binding	GOTERM_MF_DIRECT
4633	GO:0031672	A band	GOTERM_CC_DIRECT
4633	GO:0030308	negative regulation of cell growth	GOTERM_BP_DIRECT
4633	GO:0007507	heart development	GOTERM_BP_DIRECT
4633	GO:0030016	myofibril	GOTERM_CC_DIRECT

Pathways

Human Entrez ID	KEGG ID	KEGG Term
4633	hsa04260	Cardiac muscle contraction
4633	hsa04261	Adrenergic signaling in cardiomyocytes
4633	hsa04530	Tight junction
4633	hsa04510	Focal adhesion
4633	hsa04670	Leukocyte transendothelial migration
4633	hsa04810	Regulation of actin cytoskeleton
4633	hsa05414	Dilated cardiomyopathy
4633	hsa05410	Hypertrophic cardiomyopathy

Association with Disease

Protein Official Symbol	Human Entrez ID	Disease Name	Disease Id	Disease Semantic Type	Semantic score	DSI	DPI	Disease Type
MYL2	4633	CARDIOMYOPATHY, FAMILIAL HYPERTROPHIC, 10	C1834460	Disease or Syndrome	0.7	0.72	0.31	disease
MYL2	4633	Idiopathic hypertrophic subaortic stenosis	C0700053	Congenital Abnormality	0.3	0.72	0.31	disease
MYL2	4633	Cardiomyopathy, Hypertrophic, Familial	C0949658	Disease or Syndrome	0.42	0.72	0.31	disease
MYL2	4633	Obstructive asymmetric septal hypertrophy	C0597124	Disease or Syndrome	0.3	0.72	0.31	disease
MYL2	4633	Hypertrophic Cardiomyopathy	C0007194	Disease or Syndrome	0.65	0.72	0.31	disease
MYL2	4633	Charcot-Marie-Tooth Disease	C0007959	Disease or Syndrome	0.3	0.72	0.31	disease
MYL2	4633	Cardiomyopathy, Dilated	C0007193	Disease or Syndrome	0.3	0.72	0.31	group
MYL2	4633	Conduction disorder of the heart	C0264886	Disease or Syndrome	0.3	0.72	0.31	group
MYL2	4633	Congenital Fiber Type Disproportion	C0546264	Congenital Abnormality	0.3	0.72	0.31	disease

Association with Drug

Protein Official Symbol	Human Entrez ID	drug_claim_primary_name	drug_name	drug_chembl_id	interaction_types
MYL2	4633	OMECAMTIV MECARBIL	OMECAMTIV MECARBIL	CHEMBL1800955	activator