ALTITUDEOMICSDB

Coagulation factor X

AltitudeomicsDB

Protein Official symbol	F10
Aliases	F10
Chromosomal Location	13
Length	488
Uniprot ID	P00742
EC number	3.4.21.6
Protein family Information(Pfam)	PF00008;PF00594;PF00089;
PDB id	1C5M;1EZQ;1F0R;1F0S;1FAX;1FJS;1FXY;1G2L;1G2M;1HCG;1IOE;1IQE;1IQF;1IQG;1IQH;1IQI;1IQJ;1IQK;1IQL;1IQM;1IQN;1KSN;1LPG;1LPK;1LPZ;1LQD;1MQ5;1MQ6;1MSX;1NFU;1NFW;1NFX;1NFY;1NL8;1P0S;1V3X;1WU1;1XKA;1XKB;1Z6E;2BMG;2BOH;2BOK;2BQ6;2BQ7;2BQW;2CJI;2D1J;2EI6;2EI7;2EI8;2FZZ;2G00;2GD4;2H9E;2J2U;2J34;2J38;2J4I;2J94;2J95;2JKH;2P16;2P3F;2P3T;2P3U;2P93;2P94;2P95;2PHB;2PR3;2Q1J;2RA0;2UWL;2UWO;2UWP;2VH0;2VH6;2VVC;2VVU;2VVV;2VWL;2VWM;2VWN;2VWO;2W26;2W3I;2W3K;2WYG;2WYJ;2XBV;2XBW;2XBX;2XBY;2XC0;2XC4;2XC5;2Y5F;2Y5G;2Y5H;2Y7X;2Y7Z;2Y80;2Y81;2Y82;3CEN;3CS7;3ENS;3FFG;3HPT;3IIT;3K9X;3KL6;3KQB;3KQC;3KQD;3KQE;3LIW;3M36;3M37;3Q3K;3SW2;3TK5;3TK6;4A7I;4BTI;4BTT;4BTU;4Y6D;4Y71;4Y76;4Y79;4Y7A;4Y7B;4ZH8;4ZHA;5JQY;5JTC;5JZ8;5JZU;5K0H;5VOE;5VOF;6Q9F;6Q9I;6RK9;
InterPro ID	IPR017857;IPR001881;IPR013032;IPR000742;IPR000152;IPR018097;IPR035972;IPR000294;IPR012224;IPR009003;IPR001314;IPR001254;IPR018114;IPR033116;
dbSNP	rs5963 rs5961 rs121964943 rs751782758 rs121964944 rs121964939 rs121964945 rs1477329751 rs61753266 rs3211772 rs3211783 rs1393705267 rs121964946 rs747292771 rs121964942 rs770119164 rs121964947 rs372309538 rs768222784 rs104894392 rs121964941 rs121964940 rs199778916 rs376163818 rs750759634 rs758726161

Protein Protein Interaction

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AltitudeomicsDB

Protein 1	Protein 2	Combine Score
FGA	FGB	0.999
FGG	FGA	0.999
FGG	FGB	0.999
SERPINC1	F2	0.998
F8	VWF	0.996
SERPINC1	FGA	0.996
F7	F3	0.996
SERPINC1	FGG	0.995
F3	F2	0.993
SERPINC1	F9	0.992
FGG	F2	0.992
F2	FGA	0.991
GP1BA	GP9	0.991
SERPINC1	FGB	0.991
F3	TFPI	0.991
GP5	GP9	0.99
F8	F9	0.989
F13B	FGA	0.989
F2	SERPIND1	0.989
F10	F3	0.988
F11	F8	0.988
SERPINC1	PROC	0.988
THBD	F2	0.987
F3	F9	0.986
GP1BB	GP1BA	0.986
F2	VWF	0.985
ITGAM	ITGB2	0.985
F8	F2	0.985
F10	SERPINC1	0.985
F2	FGB	0.985
F11	SERPINC1	0.985
GP1BA	VWF	0.983
SERPINC1	VWF	0.983
GP5	GP1BB	0.982
F13B	FGB	0.981
FGG	SERPIND1	0.979
SERPINC1	F8	0.979
F10	TFPI	0.978
F5	F2	0.978
F7	TFPI	0.977
F13B	F13A1	0.977
SERPINC1	F13B	0.976
FGA	SERPIND1	0.975
F10	F8	0.975
GP5	VWF	0.974
GP9	VWF	0.973
VWF	F9	0.97
FGB	SERPIND1	0.97
F13B	FGG	0.969
F5	SERPINC1	0.969
THBD	PROC	0.968
FGA	PROC	0.967
F11	F9	0.966
GP1BB	VWF	0.966
F2	PROC	0.963
F7	SERPINC1	0.963
F7	GGCX	0.962
F10	SERPIND1	0.961
GGCX	F9	0.961
SERPINC1	SERPIND1	0.96
F7	F9	0.958
FGB	F13A1	0.956
F2	GGCX	0.956
FGA	F13A1	0.956
F5	F3	0.956
SERPINA5	F2	0.955
THBD	F10	0.955
F10	F5	0.954
F10	VWF	0.954
SERPINE2	F2	0.953
PROC	SERPIND1	0.953
SERPINA5	FGA	0.952
FGG	F13A1	0.952
GP5	SERPIND1	0.951
F11	F2	0.951
F11	PROC	0.95
F13A1	VWF	0.95
F11	SERPIND1	0.949
FGG	PROC	0.949
FGG	SERPINA5	0.949
SERPINA5	PROC	0.947
F2	F9	0.946
GP1BA	F2	0.945
F7	F10	0.945
VWF	SERPIND1	0.945
GP5	F8	0.944
F8	GP1BA	0.944
F2	F13A1	0.944
FGA	VWF	0.942
SERPINA5	FGB	0.942
F13B	SERPIND1	0.942
F8	GP9	0.942
F5	F13A1	0.941
F13B	F2	0.941
GP5	GP1BA	0.94
F13B	SERPINA5	0.94
F5	VWF	0.939
F5	FGA	0.939
FGB	PROC	0.938
F11	F10	0.938
F8	PROC	0.938
ITGAM	GP1BA	0.938
F10	F2	0.938
THBD	F5	0.937
F10	GGCX	0.937
VWF	PROC	0.936
F5	FGG	0.935
F2	GP9	0.935
F13B	PROC	0.935
F10	FGA	0.935
FGG	VWF	0.934
F5	FGB	0.933
F10	SERPINA5	0.933
F10	FGG	0.932
FGB	VWF	0.932
GP1BB	F8	0.932
SERPINC1	F13A1	0.931
F11	SERPINA5	0.93
F8	F13A1	0.93
F8	SERPIND1	0.929
SERPINE2	VWF	0.928
SERPINA5	VWF	0.928
FURIN	F2	0.928
F8	SERPINA5	0.928
FURIN	F9	0.927
SERPINE2	F11	0.927
F10	FGB	0.927
F11	GP1BA	0.926
F10	F13B	0.925
F5	SERPIND1	0.925
GP1BB	GP9	0.925
SERPINC1	GP1BA	0.925
ITGB2	FGA	0.925
PROC	GGCX	0.924
F5	PROC	0.924
FURIN	PROC	0.924
GP5	SERPINC1	0.923
F8	FGG	0.923
SERPINC1	F3	0.923
F5	F13B	0.921
F10	PROC	0.919
F13A1	SERPIND1	0.918
ITGB2	GP1BA	0.918
F10	GP1BA	0.917
F10	F9	0.916
SERPINE2	F10	0.915
F8	FGA	0.915
F5	F8	0.914
SERPINE2	F13A1	0.914
GP1BA	F9	0.913
F11	GP1BB	0.913
F11	GP9	0.913
GP5	F2	0.913
F10	F13A1	0.913
SERPINA5	F13A1	0.913
ITGAM	F10	0.913
GP1BA	PROC	0.913
F8	FGB	0.913
GP9	F9	0.912
SERPINE2	F8	0.912
GP5	SERPINA5	0.911
FURIN	F10	0.911
FURIN	F7	0.91
ITGB2	FGG	0.91
F5	SERPINA5	0.91
F11	GP5	0.91
SERPINC1	GP9	0.909
GP1BA	SERPIND1	0.908
GP1BB	F2	0.908
F13A1	PROC	0.906
F10	GP9	0.905
ITGB2	FGB	0.904
SERPINA5	GP1BA	0.904
ITGAM	FGG	0.904
ITGB2	PROC	0.904
GP1BB	SERPIND1	0.904
ITGB2	F10	0.903
SERPINE2	F5	0.903
ITGAM	FGB	0.903
GP1BB	F9	0.903
SERPINE2	F13B	0.902
GP9	PROC	0.902
ITGAM	FGA	0.902
ITGAM	PROC	0.902
GP1BB	F10	0.901
SERPINE2	GP1BB	0.9
GP5	F9	0.9
SERPINE2	GP9	0.9
GP5	F10	0.9
GP9	SERPIND1	0.9
SERPINA5	GP9	0.9
GP1BB	SERPINC1	0.9
SERPINE2	GP5	0.9
GP1BB	SERPINA5	0.9
GP1BB	PROC	0.9
SERPINE2	GP1BA	0.9
GP5	PROC	0.9

Gene Ontology Semantic Similarity

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#	2243 (FGA)	2266 (FGG)	462 (SERPINC1)	2157 (F8)	2155 (F7)	2152 (F3)	2147 (F2)	2811 (GP1BA)	2814 (GP5)	2159 (F10)	2160 (F11)	7056 (THBD)	2812 (GP1BB)	3684 (ITGAM)	2153 (F5)	2815 (GP9)	7450 (VWF)	2244 (FGB)	2677 (GGCX)	5104 (SERPINA5)	5270 (SERPINE2)	5624 (PROC)	2162 (F13A1)	5045 (FURIN)	3689 (ITGB2)	2158 (F9)	7035 (TFPI)	3053 (SERPIND1)
2243 (FGA)	1.00	1.00	0.66	1.00	0.57	0.61	0.61	0.63	1.00	0.60	0.63	0.64	0.66	0.71	1.00	1.00	0.80	0.98	0.21	0.54	0.64	0.63	0.21	0.52	0.67	0.55	0.14	0.14
2266 (FGG)	1.00	1.00	0.66	1.00	0.57	0.61	0.61	0.63	1.00	0.60	0.63	0.64	0.66	0.71	1.00	1.00	0.80	0.98	0.21	0.54	0.64	0.63	0.21	0.52	0.67	0.55	0.14	0.14
462 (SERPINC1)	0.66	0.66	1.00	1.00	0.56	0.68	0.56	0.62	1.00	0.59	0.62	0.64	0.71	0.72	1.00	1.00	0.75	0.67	0.16	0.73	0.79	0.62	0.16	0.70	0.63	0.53	0.54	0.54
2157 (F8)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.16	1.00	1.00	1.00	0.16	1.00	1.00	1.00	0.13	0.13
2155 (F7)	0.57	0.57	0.56	1.00	1.00	0.84	0.72	0.48	1.00	0.87	0.97	0.49	0.54	0.63	1.00	1.00	0.62	0.60	0.20	0.46	0.50	0.97	0.20	0.74	0.57	0.85	0.10	0.10
2152 (F3)	0.61	0.61	0.68	1.00	0.84	1.00	0.72	0.55	1.00	0.96	0.85	0.57	0.59	0.66	1.00	1.00	0.68	0.63	0.16	0.64	0.58	0.85	0.16	0.74	0.60	0.77	0.10	0.10
2147 (F2)	0.61	0.61	0.56	1.00	0.72	0.72	1.00	0.60	1.00	0.72	0.71	0.68	0.66	0.60	1.00	1.00	0.61	0.63	0.16	0.61	0.71	0.71	0.16	0.64	0.63	0.68	0.10	0.10
2811 (GP1BA)	0.63	0.63	0.62	1.00	0.48	0.55	0.60	1.00	1.00	0.52	0.56	0.80	0.85	0.70	1.00	1.00	0.66	0.65	0.16	0.49	0.55	0.56	0.16	0.45	0.70	0.46	0.11	0.11
2814 (GP5)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.16	1.00	1.00	1.00	0.16	1.00	1.00	1.00	0.13	0.13
2159 (F10)	0.60	0.60	0.59	1.00	0.87	0.96	0.72	0.52	1.00	1.00	0.88	0.54	0.58	0.66	1.00	1.00	0.63	0.62	0.16	0.58	0.57	0.88	0.16	0.69	0.59	0.79	0.11	0.11
2160 (F11)	0.63	0.63	0.62	1.00	0.97	0.85	0.71	0.56	1.00	0.88	1.00	0.58	0.62	0.71	1.00	1.00	0.66	0.65	0.16	0.49	0.55	1.00	0.16	0.72	0.61	0.85	0.11	0.11
7056 (THBD)	0.64	0.64	0.64	1.00	0.49	0.57	0.68	0.80	1.00	0.54	0.58	1.00	0.88	0.72	1.00	1.00	0.66	0.66	0.16	0.50	0.56	0.58	0.16	0.46	0.72	0.47	0.12	0.12
2812 (GP1BB)	0.66	0.66	0.71	1.00	0.54	0.59	0.66	0.85	1.00	0.58	0.62	0.88	1.00	0.73	1.00	1.00	0.71	0.67	0.16	0.52	0.59	0.62	0.16	0.49	0.75	0.52	0.11	0.11
3684 (ITGAM)	0.71	0.71	0.72	1.00	0.63	0.66	0.60	0.70	1.00	0.66	0.71	0.72	0.73	1.00	1.00	1.00	0.71	0.72	0.16	0.57	0.65	0.71	0.16	0.54	0.81	0.59	0.11	0.11
2153 (F5)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.16	1.00	1.00	1.00	0.16	1.00	1.00	1.00	0.13	0.13
2815 (GP9)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.16	1.00	1.00	1.00	0.16	1.00	1.00	1.00	0.13	0.13
7450 (VWF)	0.80	0.80	0.75	1.00	0.62	0.68	0.61	0.66	1.00	0.63	0.66	0.66	0.71	0.71	1.00	1.00	1.00	0.82	0.16	0.62	0.64	0.66	0.16	0.60	0.70	0.60	0.10	0.10
2244 (FGB)	0.98	0.98	0.67	1.00	0.60	0.63	0.63	0.65	1.00	0.62	0.65	0.66	0.67	0.72	1.00	1.00	0.82	1.00	0.21	0.56	0.65	0.65	0.21	0.54	0.68	0.58	0.13	0.13
2677 (GGCX)	0.21	0.21	0.16	0.16	0.20	0.16	0.16	0.16	0.16	0.16	0.16	0.16	0.16	0.16	0.16	0.16	0.16	0.21	1.00	0.16	0.16	0.16	0.20	0.28	0.16	0.20	0.07	0.07
5104 (SERPINA5)	0.54	0.54	0.73	1.00	0.46	0.64	0.61	0.49	1.00	0.58	0.49	0.50	0.52	0.57	1.00	1.00	0.62	0.56	0.16	1.00	0.84	0.49	0.16	0.60	0.55	0.46	0.35	0.35
5270 (SERPINE2)	0.64	0.64	0.79	1.00	0.50	0.58	0.71	0.55	1.00	0.57	0.55	0.56	0.59	0.65	1.00	1.00	0.64	0.65	0.16	0.84	1.00	0.55	0.16	0.61	0.60	0.49	0.47	0.47
5624 (PROC)	0.63	0.63	0.62	1.00	0.97	0.85	0.71	0.56	1.00	0.88	1.00	0.58	0.62	0.71	1.00	1.00	0.66	0.65	0.16	0.49	0.55	1.00	0.16	0.72	0.61	0.85	0.11	0.11
2162 (F13A1)	0.21	0.21	0.16	0.16	0.20	0.16	0.16	0.16	0.16	0.16	0.16	0.16	0.16	0.16	0.16	0.16	0.16	0.21	0.20	0.16	0.16	0.16	1.00	0.28	0.16	0.20	0.07	0.07
5045 (FURIN)	0.52	0.52	0.70	1.00	0.74	0.74	0.64	0.45	1.00	0.69	0.72	0.46	0.49	0.54	1.00	1.00	0.60	0.54	0.28	0.60	0.61	0.72	0.28	1.00	0.57	0.75	0.35	0.35
3689 (ITGB2)	0.67	0.67	0.63	1.00	0.57	0.60	0.63	0.70	1.00	0.59	0.61	0.72	0.75	0.81	1.00	1.00	0.70	0.68	0.16	0.55	0.60	0.61	0.16	0.57	1.00	0.56	0.10	0.10
2158 (F9)	0.55	0.55	0.53	1.00	0.85	0.77	0.68	0.46	1.00	0.79	0.85	0.47	0.52	0.59	1.00	1.00	0.60	0.58	0.20	0.46	0.49	0.85	0.20	0.75	0.56	1.00	0.10	0.10
7035 (TFPI)	0.14	0.14	0.54	0.13	0.10	0.10	0.10	0.11	0.13	0.11	0.11	0.12	0.11	0.11	0.13	0.13	0.10	0.13	0.07	0.35	0.47	0.11	0.07	0.35	0.10	0.10	1.00	1.00
3053 (SERPIND1)	0.14	0.14	0.54	0.13	0.10	0.10	0.10	0.11	0.13	0.11	0.11	0.12	0.11	0.11	0.13	0.13	0.10	0.13	0.07	0.35	0.47	0.11	0.07	0.35	0.10	0.10	1.00	1.00

Association with High Altitude

Protein Official symbol	Source Organism	Tissue of Expression	Level of hypoxia	Altitude	Duration of experiment	Level of expression	Fold change	Experiment details	geographical location	ethnicity of the patients	Control group	Control (Fold change)	Reference (PMID)
F10	Mice	Blood	8% Oxygen	7600 m	24 hours	upregulated	44.3	RT-qPCR	Western US	C57BL/6 mice	5.8	7600m mice(8% oxygen with Fenofibrate injections Vs Baseline normoxia mice (21% oxygen)	24183776
F10	Mice	Blood	8% Oxygen	7600 m	24 hours	upregulated	21.8	RT-qPCR	Western US	C57BL/6 mice	5.8	7600m mice(8% oxygen with no Fenofibrate injections Vs Baseline normoxia mice (21% oxygen)	24183776
F10	Human	Blood	-	4000 m	24 hours	upregulated	3	RT-qPCR	The South Atlantic States, USA	Americans	1	Soldier exposed to high altitude compared to their low altitude profile	24183776
F10	Human	Blood	-	3500 m	24 hours	upregulated	2.4	RT-qPCR	The South Atlantic States, USA	Americans	1	Soldier exposed to high altitude compared to their low altitude profile	24183776
F10	Human	Blood	-	3000m	24 hours	upregulated	1.5	RT-qPCR	The South Atlantic States, USA	Americans	1	Soldier exposed to high altitude compared to their low altitude profile	24183776

Association with TF

TF	TF Entrez	Gene	Gene Entrez	Type	PMID	Database
MYC	4609	F10	2159	proximal_filtered	22955619	TRANSFAC
HNF4A	3172	F10	2159	proximal_filtered	22955619	TRANSFAC
SP1	6667	F10	2159	Repression	8557038	TRUSST

Association with miRNA

miRTarBase ID	miRNA	Species (miRNA)	Protein Official Symbol	Human Entrez ID	Species (Target Gene)	Experiments	Support Type	References (PMID)
MIRT016852	hsa-miR-335-5p	Homo sapiens	F10	2159	Homo sapiens	Microarray	Functional MTI (Weak)	18185580

Gene Ontology

ID	GO ID	GO Term	GO Type
2159	GO:0006888	ER to Golgi vesicle-mediated transport	GOTERM_BP_DIRECT
2159	GO:0004252	serine-type endopeptidase activity	GOTERM_MF_DIRECT
2159	GO:0007597	blood coagulation	GOTERM_BP_DIRECT
2159	GO:0007596	blood coagulation	GOTERM_BP_DIRECT
2159	GO:0030335	positive regulation of cell migration	GOTERM_BP_DIRECT
2159	GO:0007598	blood coagulation	GOTERM_BP_DIRECT
2159	GO:0005788	endoplasmic reticulum lumen	GOTERM_CC_DIRECT
2159	GO:0005886	plasma membrane	GOTERM_CC_DIRECT
2159	GO:0005576	extracellular region	GOTERM_CC_DIRECT
2159	GO:0031233	intrinsic component of external side of plasma membrane	GOTERM_CC_DIRECT
2159	GO:0005796	Golgi lumen	GOTERM_CC_DIRECT
2159	GO:0017187	peptidyl-glutamic acid carboxylation	GOTERM_BP_DIRECT
2159	GO:0005509	calcium ion binding	GOTERM_MF_DIRECT
2159	GO:0051897	positive regulation of protein kinase B signaling	GOTERM_BP_DIRECT
2159	GO:0005543	phospholipid binding	GOTERM_MF_DIRECT
2159	GO:0006465	signal peptide processing	GOTERM_BP_DIRECT
2159	GO:0005515	protein binding	GOTERM_MF_DIRECT

Pathways

Human Entrez ID	KEGG ID	KEGG Term
2159	hsa04610	Complement and coagulation cascades

Association with Disease

Protein Official Symbol	Human Entrez ID	Disease Name	Disease Id	Disease Semantic Type	Semantic score	DSI	DPI	Disease Type
F10	2159	Thrombosis	C0040053	Pathologic Function	0.3	0.636	0.448	phenotype
F10	2159	Thrombus	C0087086	Pathologic Function	0.3	0.636	0.448	phenotype
F10	2159	Blood Coagulation Disorders	C0005779	Disease or Syndrome	0.4	0.636	0.448	group
F10	2159	Factor X Deficiency	C0015519	Disease or Syndrome	0.75	0.636	0.448	disease

Association with Drug

Protein Official Symbol	Human Entrez ID	drug_claim_primary_name	drug_name	drug_chembl_id	interaction_types
F10	2159	2-O, 3-O DESULFATED HEPARIN	None	None	None
F10	2159	ANTIHEMOPHILIC FACTOR	ANTIHEMOPHILIC FACTOR	CHEMBL2108175	None
F10	2159	ANTIHEMOPHILIC FACTOR	ANTIHEMOPHILIC FACTOR	CHEMBL2108175	None
F10	2159	ANTITHROMBIN	None	None	None
F10	2159	APIXABAN	APIXABAN	CHEMBL231779	None
F10	2159	APIXABAN	APIXABAN	CHEMBL231779	inhibitor
F10	2159	APIXABAN	APIXABAN	CHEMBL231779	inhibitor
F10	2159	APIXABAN	APIXABAN	CHEMBL231779	inhibitor
F10	2159	AVE5026	None	None	inhibitor
F10	2159	BETRIXABAN	BETRIXABAN	CHEMBL512351	inhibitor
F10	2159	BETRIXABAN	BETRIXABAN	CHEMBL512351	inhibitor
F10	2159	BETRIXABAN	BETRIXABAN	CHEMBL512351	None
F10	2159	COAGULATION FACTOR IX	CHOLESTEROL	CHEMBL112570	None
F10	2159	COAGULATION FACTOR IX	CHOLESTEROL	CHEMBL112570	activator
F10	2159	COAGULATION FACTOR IX	CHOLESTEROL	CHEMBL112570	None
F10	2159	COAGULATION FACTOR VIIA	None	None	None
F10	2159	COAGULATION FACTOR VIIA	None	None	None
F10	2159	CS-3030	None	None	None
F10	2159	DANAPAROID	DANAPAROID SODIUM	CHEMBL1201534	inhibitor
F10	2159	EDOXABAN TOSYLATE	EDOXABAN TOSYLATE	CHEMBL2105682	inhibitor
F10	2159	EDOXABAN	EDOXABAN	CHEMBL1269025	inhibitor
F10	2159	EMICIZUMAB	EMICIZUMAB	CHEMBL3833393	None
F10	2159	EDOXABAN	EDOXABAN	CHEMBL1269025	None
F10	2159	ENOXAPARIN	ENOXAPARIN	CHEMBL1201685	inhibitor
F10	2159	EP42675	None	None	None
F10	2159	EP217609	None	None	None
F10	2159	ERIBAXABAN	ERIBAXABAN	CHEMBL476186	inhibitor
F10	2159	FACTOR IX	None	None	None
F10	2159	FACTOR VIII	None	None	None
F10	2159	FONDAPARINUX SODIUM	FONDAPARINUX SODIUM	CHEMBL1200644	inhibitor
F10	2159	HEPARIN	HEPARIN	CHEMBL1909300	None
F10	2159	HEPARIN	HEPARIN	CHEMBL1909300	None
F10	2159	IDRAPARINUX	IDRAPARINUX	CHEMBL1908845	inhibitor
F10	2159	IDRAPARINUX	IDRAPARINUX	CHEMBL1908845	None
F10	2159	IDRABIOTAPARINUX	None	None	None
F10	2159	IDRAPARINUX SODIUM	IDRAPARINUX SODIUM	CHEMBL1908371	inhibitor
F10	2159	LETAXABAN	LETAXABAN	CHEMBL1095032	inhibitor
F10	2159	LY-517717	CHEMBL1271162	CHEMBL1271162	None
F10	2159	MENADIONE	MENADIONE	CHEMBL590	None
F10	2159	NONACOG ALFA	NONACOG ALFA	CHEMBL2109205	None
F10	2159	OCTOPAMINE	OCTOPAMINE	CHEMBL53929	inhibitor
F10	2159	OTAMIXABAN	OTAMIXABAN	CHEMBL46618	inhibitor
F10	2159	OTAMIXABAN	OTAMIXABAN	CHEMBL46618	None
F10	2159	PD-348292	ERIBAXABAN	CHEMBL476186	inhibitor
F10	2159	RECOMBINANT FACTOR IX FC FUSION PROTEIN	None	None	None
F10	2159	RECOMBINANT HUMAN THROMBIN	None	None	None
F10	2159	RECOMBINANT ANTIHEMOPHILIC FACTOR	None	None	None
F10	2159	RFIX	None	None	None
F10	2159	RIVAROXABAN	RIVAROXABAN	CHEMBL198362	inhibitor
F10	2159	RIVAROXABAN	RIVAROXABAN	CHEMBL198362	inhibitor
F10	2159	RIVAROXABAN	RIVAROXABAN	CHEMBL198362	None
F10	2159	SR-123781A	None	None	inhibitor
F10	2159	TAK-442	LETAXABAN	CHEMBL1095032	None
F10	2159	TAK-442	LETAXABAN	CHEMBL1095032	inhibitor
F10	2159	THROMBIN	THROMBIN	CHEMBL2108110	None
F10	2159	TINZAPARIN	TINZAPARIN SODIUM	CHEMBL1201414	None