ALTITUDEOMICSDB

Heparin cofactor 2

AltitudeomicsDB

Protein Official symbol	SERPIND1
Aliases	SERPIND1 HCF2
Chromosomal Location	22
Length	499
Uniprot ID	P05546
EC number	None
Protein family Information(Pfam)	PF00079;
PDB id	1JMJ;1JMO;2NAT;2NCU;2NCV;2NCW;6J12;6KBO;6KBV;
InterPro ID	IPR033831;IPR023795;IPR023796;IPR000215;IPR036186;IPR042178;IPR042185;
dbSNP	rs5905 rs165867 rs34324685 rs11542069 rs5907 rs1042435 rs5904 rs142451096 rs121912420

Protein Protein Interaction

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AltitudeomicsDB

Protein 1	Protein 2	Combine Score
FGA	FGB	0.999
FGG	FGA	0.999
FGG	FGB	0.999
APOA1	APOB	0.998
APOA2	APOA1	0.998
AHSG	ALB	0.998
SERPINC1	F2	0.998
AHSG	AFP	0.997
APOA2	APOB	0.996
AHSG	APOA1	0.996
F8	VWF	0.996
SERPINC1	FGA	0.996
SERPINC1	FGG	0.995
AHSG	APOA2	0.995
SERPINC1	ITIH2	0.994
APOE	APOB	0.994
FGG	F2	0.992
PCSK9	APOB	0.992
F2	FGA	0.991
SERPINC1	FGB	0.991
AHSG	FGG	0.991
ALB	APOA1	0.99
AHSG	ITIH2	0.99
AFP	GPC3	0.989
F13B	FGA	0.989
AHSG	FGA	0.989
ITIH2	FGG	0.989
F2	SERPIND1	0.989
AFP	APOA2	0.989
FN1	ALB	0.989
SERPINC1	PROC	0.988
F11	F8	0.988
APOE	APOA1	0.987
AHSG	APOB	0.987
SERPINC1	ALB	0.987
AHSG	SERPINC1	0.987
AHSG	SPP2	0.986
ALB	APOB	0.986
F10	SERPINC1	0.985
F8	F2	0.985
F2	VWF	0.985
F2	FGB	0.985
F11	SERPINC1	0.985
AHSG	TF	0.985
ITIH2	FGA	0.985
AFP	IGFBP1	0.984
AFP	APOB	0.984
FGG	APOA1	0.984
SERPINA1	AFP	0.983
SERPINC1	VWF	0.983
IL6	ALB	0.983
SERPINA1	ALB	0.983
GP1BA	VWF	0.983
ITIH2	APOA1	0.983
IL6	TIMP1	0.982
TF	ALB	0.982
AHSG	IGFBP1	0.982
FGA	ALB	0.982
TF	APOA2	0.982
SERPINA1	CP	0.981
APOA2	ALB	0.981
APOA5	APOB	0.981
F13B	FGB	0.981
FGG	ALB	0.98
ALB	CP	0.98
FGG	APOB	0.98
ITIH2	SERPIND1	0.98
FN1	VWF	0.98
ITIH2	SERPINA10	0.979
APOA2	APOE	0.979
SERPINC1	F8	0.979
FGG	SERPIND1	0.979
AFP	APOA1	0.979
SERPINC1	APOA1	0.978
F5	F2	0.978
FGA	APOA1	0.978
CST3	ALB	0.978
FGA	SERPINA10	0.978
FGA	APOB	0.977
F13B	F13A1	0.977
TF	APOA1	0.977
SERPINC1	F13B	0.976
FGA	SERPIND1	0.975
F10	F8	0.975
AHSG	PROC	0.975
APOA2	ITIH2	0.974
SERPINA1	AHSG	0.974
GP5	VWF	0.974
ITIH2	APOB	0.974
SERPINC1	APOB	0.974
IL6	KNG1	0.974
AHSG	F2	0.973
AHSG	FGB	0.973
IGFBP1	APOB	0.973
FN1	IGFBP5	0.973
ALB	VWF	0.973
IL6	SERPINC1	0.973
F11	KNG1	0.972
FN1	TIMP1	0.972
AFP	ITIH2	0.972
SERPINC1	KNG1	0.972
APOL1	APOA1	0.972
ITIH2	ALB	0.972
APOA2	FGA	0.972
ALB	C3	0.972
AFP	FGG	0.972
FGA	SPP2	0.972
IL6	FN1	0.971
ALB	KNG1	0.971
IL6	APOA1	0.971
SERPINA1	IL6	0.971
APOA5	SERPINC1	0.97
APOA5	APOE	0.97
FGG	SERPINA10	0.97
FGB	SERPIND1	0.97
SERPINA1	APOA1	0.97
APOA2	FGG	0.97
FGB	ALB	0.969
IL6	APOE	0.969
F5	SERPINC1	0.969
F13B	FGG	0.969
APOA5	APOA2	0.969
IL6	IGFBP1	0.969
FGG	SPP2	0.969
ALB	IGFBP1	0.969
SERPINC1	SERPINA10	0.968
ALB	APOE	0.968
APOA1	SERPIND1	0.968
FGA	PROC	0.967
TF	ITIH2	0.967
TF	CP	0.967
C3	APOA1	0.967
TF	AFP	0.966
SERPINA1	TF	0.966
APOA5	AFP	0.966
PCSK9	APOE	0.966
SERPINA10	PROC	0.966
AFP	KNG1	0.966
IGFBP1	APOA1	0.965
APOA2	IGFBP1	0.965
FGG	BPIFB2	0.965
AFP	FGA	0.965
AHSG	SERPINA10	0.965
APOB	SERPIND1	0.964
AHSG	SERPIND1	0.964
APOA2	SERPIND1	0.964
AHSG	CP	0.964
F2	PROC	0.963
CP	C3	0.963
SERPINA1	C3	0.963
APOA5	PCSK9	0.963
APOA5	ALB	0.963
PROC	SPP2	0.963
APOA2	SERPINC1	0.963
AFP	SERPINC1	0.962
AHSG	KNG1	0.961
APOA2	C3	0.961
F10	SERPIND1	0.961
F2	KNG1	0.961
TF	C3	0.961
SERPINA1	APOA2	0.96
APOA5	FGA	0.96
APOA5	AHSG	0.96
PCSK9	APOA1	0.96
SERPINC1	SERPIND1	0.96
F2	ALB	0.959
NOTUM	GPC3	0.959
C4A	ALB	0.959
FGA	BPIFB2	0.959
APOE	C3	0.959
FGA	IGFBP1	0.959
CST3	APOE	0.959
IL6	C3	0.958
F8	ALB	0.958
C4A	SERPINC1	0.958
ITIH2	PROC	0.957
IGFBP1	SERPIND1	0.957
AFP	CP	0.957
AFP	C3	0.957
CP	APOA1	0.957
IL6	APOB	0.957
SERPINC1	SPP2	0.957
SERPINA1	FGA	0.957
C4A	AFP	0.957
FGG	IGFBP1	0.957
FGB	F13A1	0.956
AFP	ALB	0.956
IL6	CST3	0.956
SERPINC1	C3	0.956
AHSG	C3	0.956
ALB	TIMP1	0.956
ITIH2	SPP2	0.956
FN1	C3	0.956
FGA	F13A1	0.956
SERPINC1	CP	0.956
AHSG	GPC3	0.956
SERPINA1	FGG	0.955
APOA5	FGG	0.955
FGG	CP	0.954
KNG1	C3	0.954
SERPINC1	FN1	0.954
TF	KNG1	0.954
F10	VWF	0.954
SERPINA1	KNG1	0.954
F10	F5	0.954
PROC	SERPIND1	0.953
FGG	KNG1	0.953
CST3	TIMP1	0.953
ITIH2	IGFBP1	0.953
AHSG	BPIFB2	0.953
TF	FGG	0.953
APOA5	APOA1	0.953
KNG1	SERPIND1	0.952
AFP	FN1	0.952
APOA5	SERPINA1	0.952
AFP	SERPIND1	0.952
FN1	APOE	0.952
FGG	F13A1	0.952
ALB	BPIFB2	0.952
SERPINA1	APOB	0.952
ALB	SERPIND1	0.952
SERPINA1	C4A	0.951
KNG1	APOA1	0.951
AFP	BPIFB2	0.951
C4A	APOA1	0.951
SERPINA1	FGB	0.951
F11	F2	0.951
GP5	SERPIND1	0.951
SERPINC1	IGFBP1	0.951
KNG1	VWF	0.951
F13A1	VWF	0.95
F11	PROC	0.95
C3	APOB	0.95
SERPINA1	APOE	0.95
SERPINA1	ITIH2	0.95
TF	SERPINC1	0.95
FN1	KNG1	0.95
SERPINA1	FN1	0.949
FGG	PROC	0.949
F11	SERPIND1	0.949
TF	APOB	0.949
CP	APOB	0.949
APOA2	APOL1	0.949
APOL1	APOE	0.949
IL6	CP	0.949
APOA5	KNG1	0.949
C4A	KNG1	0.949
IGFBP1	BPIFB2	0.948
GPC3	ALB	0.948
FGA	KNG1	0.948
CP	APOE	0.948
AHSG	IL6	0.947
FGB	KNG1	0.947
VWF	TIMP1	0.947
APOB	SPP2	0.947
ALB	PROC	0.947
SERPINA10	APOB	0.946
IL6	AFP	0.946
APOA5	TF	0.946
APOA2	CP	0.946
CST3	APOA1	0.946
APOA5	C3	0.946
GP1BA	F2	0.945
SERPINA1	F5	0.945
FN1	IGFBP1	0.945
APOA2	KNG1	0.945
FGA	CP	0.945
VWF	SERPIND1	0.945
SERPINA10	SPP2	0.945
FGA	C3	0.945
C4A	TF	0.945
F8	GP1BA	0.944
APOE	TIMP1	0.944
C4A	APOE	0.944
GP5	F8	0.944
AHSG	CST3	0.944
F2	F13A1	0.944
C4A	IL6	0.944
ITIH2	BPIFB2	0.943
F5	SERPINA10	0.943
AHSG	APOE	0.942
AFP	F2	0.942
F13B	SERPIND1	0.942
TF	FGA	0.942
APOL1	ALB	0.942
APOA5	IGFBP1	0.942
FGA	VWF	0.942
MATN3	FN1	0.942
KNG1	CP	0.942
ITIH2	CP	0.941
F13B	F2	0.941
F5	F13A1	0.941
ITIH2	KNG1	0.941
KNG1	APOE	0.941
GP5	GP1BA	0.94
ITIH2	C3	0.94
FGG	C3	0.94
APOA5	ITIH2	0.94
C4A	CP	0.94
SERPINA1	TIMP1	0.94
SERPINA1	SERPINC1	0.94
IGFBP1	TIMP1	0.94
SERPINA1	CST3	0.94
APLP2	APOE	0.94
F8	FN1	0.939
F5	VWF	0.939
FN1	APOA1	0.939
F5	FGA	0.939
FN1	CP	0.939
CST3	APOB	0.939
FGB	PROC	0.938
C4A	C3	0.938
C4A	FGA	0.938
PCSK9	ALB	0.938
GPC3	IGFBP1	0.938
APOA5	C4A	0.938
GPC3	APOA1	0.938
F8	PROC	0.938
C4A	F5	0.938
F11	F10	0.938
FN1	APOB	0.938
F10	F2	0.938
APOA5	SERPIND1	0.937
APOL1	APOB	0.937
CST3	C3	0.937
C4A	AHSG	0.937
FN1	IGFBP4	0.937
TF	APOE	0.937
SERPINA1	VWF	0.937
AHSG	FN1	0.936
C4A	FGG	0.936
C4A	SERPIND1	0.936
VWF	PROC	0.936
F10	FGA	0.935
F5	KNG1	0.935
F13B	PROC	0.935
APOB	BPIFB2	0.935
FN1	FGA	0.935
F5	FGG	0.935
FGG	APOE	0.935
SERPINC1	APOE	0.934
IGFBP4	TIMP1	0.934
CST3	FN1	0.934
IL6	MFI2	0.934
C4A	FN1	0.934
GPC3	FN1	0.934
SERPINA1	APOL1	0.934
FGG	VWF	0.934
AHSG	F13A1	0.934
LAMB2	FN1	0.933
KNG1	APOB	0.933
F5	FGB	0.933
APOA1	PROC	0.933
SERPINA1	SERPIND1	0.933
TF	SERPIND1	0.933
FGA	APOE	0.933
FGB	VWF	0.932
TIMP1	SERPIND1	0.932
APOA1	TIMP1	0.932
NOTUM	ALB	0.932
CST3	APOL1	0.932
AHSG	NOTUM	0.932
MATN3	APOB	0.932
SERPINA1	F8	0.932
F10	FGG	0.932
APOA1	BPIFB2	0.931
F5	APOE	0.931
APOA2	BPIFB2	0.931
APOA5	PROC	0.931
C4A	ITIH2	0.931
SERPINC1	F13A1	0.931
F8	KNG1	0.931
C4A	APOA2	0.931
F5	APOA1	0.931
C4A	APOB	0.931
MFI2	CP	0.93
GPC3	APOB	0.93
APOA5	BPIFB2	0.93
SERPINA10	SERPIND1	0.93
IL6	IGFBP5	0.93
GPC3	APOA2	0.93
F8	F13A1	0.93
F5	C3	0.93
IGFBP5	TIMP1	0.93
FN1	F13A1	0.93
FN1	FGB	0.93
FN1	FGG	0.93
F5	APOB	0.929
F5	ALB	0.929
F8	SERPIND1	0.929
IL6	PCSK9	0.929
C3	SERPIND1	0.929
PROC	APOB	0.928
IL6	IGFBP4	0.928
NOTUM	AFP	0.928
FN1	SERPIND1	0.928
C4A	PROC	0.927
KNG1	SERPINA10	0.927
SERPIND1	BPIFB2	0.927
APOL1	C3	0.927
F10	FGB	0.927
IGFBP4	TMEM132A	0.927
APOA5	APOL1	0.927
NOTUM	IGFBP1	0.926
IL6	GPC3	0.926
CST3	CP	0.926
AFP	PCSK9	0.926
NOTUM	BPIFB2	0.926
CST3	APOA2	0.926
IL6	APOA2	0.926
APOA2	PROC	0.926
F11	GP1BA	0.926
SERPINA1	PROC	0.925
IGFBP1	PROC	0.925
SERPINC1	GP1BA	0.925
F5	SERPIND1	0.925
F10	F13B	0.925
APOE	SERPIND1	0.925
AFP	PROC	0.925
SERPINA1	SERPINA10	0.924
ALB	SPP2	0.924
F5	PROC	0.924
SERPINA1	IGFBP1	0.924
APOA2	PCSK9	0.924
KNG1	PROC	0.924
FN1	PCSK9	0.923
GPC3	SERPINC1	0.923
F8	FGG	0.923
CST3	SERPINC1	0.923
GP5	SERPINC1	0.923
TF	FN1	0.923
GPC3	BPIFB2	0.923
KNG1	F13A1	0.923
MFI2	ALB	0.922
ALB	IGFBP4	0.922
AFP	SPP2	0.922
IGFBP1	CP	0.922
CST3	APLP2	0.922
FGA	PCSK9	0.922
LAMB2	ALB	0.922
C3	TIMP1	0.921
AFP	TIMP1	0.921
AHSG	F5	0.921
PCSK9	IGFBP1	0.921
GPC3	FGG	0.921
FGG	PCSK9	0.921
PCSK9	APLP2	0.921
F5	FN1	0.921
IL6	FGA	0.921
IGFBP1	C3	0.921
ALB	IGFBP5	0.921
KNG1	TIMP1	0.921
F5	F13B	0.921
NOTUM	FGA	0.92
IGFBP4	IGFBP5	0.92
IGFBP1	IGFBP4	0.92
AFP	APOE	0.92
TF	IGFBP1	0.92
AHSG	TIMP1	0.92
FGA	IGFBP4	0.92
KNG1	SPP2	0.92
IL6	PROC	0.92
ALB	APLP2	0.92
IGFBP4	APOE	0.92
SERPINA1	F13A1	0.92
NOTUM	FGG	0.92
FN1	APLP2	0.92
F10	PROC	0.919
KNG1	APLP2	0.919
C4A	SERPINA10	0.919
CP	SERPIND1	0.919
GPC3	APOE	0.919
TF	BPIFB2	0.919
NOTUM	ITIH2	0.919
DNAJC3	IL6	0.919
TF	CST3	0.919
APOB	TIMP1	0.919
IL6	APOL1	0.918
APOA5	IL6	0.918
SERPINA1	IGFBP4	0.918
GPC3	SERPIND1	0.918
APOA1	SPP2	0.918
F13A1	SERPIND1	0.918
ITIH2	FN1	0.918
LAMB2	IGFBP4	0.918
IL6	FGG	0.918
TF	IL6	0.918
C4A	CST3	0.918
F5	CP	0.918
GP1BA	KNG1	0.917
TF	F5	0.917
CP	TIMP1	0.917
ITIH2	TMEM132A	0.917
APOA5	NOTUM	0.917
F10	GP1BA	0.917
APOL1	SERPIND1	0.917
F5	ITIH2	0.917
C3	SPP2	0.917
GPC3	FGA	0.917
SERPINC1	IGFBP4	0.917
GPC3	ITIH2	0.917
SERPINC1	TIMP1	0.917
MFI2	APOE	0.916
IGFBP1	IGFBP5	0.916
SERPINC1	BPIFB2	0.916
LAMB2	SERPIND1	0.916
LAMB2	IGFBP5	0.916
APOE	PROC	0.916
CST3	IGFBP5	0.916
SERPIND1	SPP2	0.916
C3	PROC	0.915
SERPINC1	PCSK9	0.915
APOL1	FGA	0.915
IGFBP1	APOE	0.915
AHSG	MFI2	0.915
C4A	IGFBP5	0.915
CP	SPP2	0.915
AFP	APOL1	0.915
GPC3	IGFBP5	0.915
F8	FGA	0.915
NOTUM	APOA1	0.915
APOA2	F5	0.914
AHSG	PCSK9	0.914
PCSK9	PROC	0.914
APOA2	SERPINA10	0.914
APOA5	GPC3	0.914
FGG	IGFBP4	0.914
MFI2	C3	0.914
IL6	F5	0.914
F5	F8	0.914
GPC3	TIMP1	0.913
F8	FGB	0.913
AHSG	IGFBP4	0.913
IGFBP4	SERPIND1	0.913
ITIH2	APOE	0.913
CST3	FGA	0.913
ALB	SERPINA10	0.913
APOA5	F5	0.913
NOTUM	APOB	0.913
FN1	MFI2	0.913
GP1BA	PROC	0.913
C4A	TIMP1	0.913
NOTUM	PROC	0.913
FN1	APOL1	0.913
AFP	MFI2	0.913
GP5	F2	0.913
F10	F13A1	0.913
IL6	SERPIND1	0.913
TF	TMEM132A	0.913
C4A	IGFBP1	0.913
APOA2	FN1	0.913
AHSG	VWF	0.912
MATN3	ALB	0.912
GPC3	SERPINA10	0.912
APOL1	CP	0.912
TF	APOL1	0.912
NOTUM	APOA2	0.912
AHSG	MATN3	0.912
SERPINA1	PCSK9	0.912
APOE	IGFBP5	0.912
PCSK9	IGFBP4	0.912
CP	PROC	0.912
MATN3	AFP	0.912
DNAJC3	APOB	0.912
SERPINC1	APOL1	0.912
C4A	APOL1	0.912
ALB	F13A1	0.912
AHSG	APOL1	0.912
MFI2	SERPINA10	0.912
F13A1	TIMP1	0.911
APOA5	SERPINA10	0.911
APOA2	SPP2	0.911
MFI2	APOB	0.911
TF	GPC3	0.911
SERPINA10	C3	0.911
CST3	AFP	0.911
APOA5	MFI2	0.911
APOA5	SPP2	0.911
TF	MFI2	0.911
IGFBP1	KNG1	0.911
NOTUM	SERPIND1	0.911
CST3	KNG1	0.911
ITIH2	APLP2	0.911
MATN3	IGFBP1	0.911
SERPINA1	GPC3	0.911
TF	PROC	0.911
CP	APLP2	0.911
IGFBP4	APOA1	0.91
APOL1	PCSK9	0.91
SERPIND1	TMEM132A	0.91
APOL1	KNG1	0.91
PCSK9	SERPIND1	0.91
SERPINA1	SPP2	0.91
DNAJC3	ALB	0.91
APOA5	CP	0.91
PROC	BPIFB2	0.91
AFP	IGFBP4	0.91
ITIH2	PCSK9	0.91
CST3	IGFBP1	0.91
F11	GP5	0.91
F5	IGFBP1	0.91
MFI2	SERPIND1	0.91
CST3	BPIFB2	0.909
APOA1	IGFBP5	0.909
IL6	MATN3	0.909
AFP	F5	0.909
CP	BPIFB2	0.909
C4A	IGFBP4	0.909
APLP2	APOB	0.909
SERPINA1	IGFBP5	0.909
SERPINA1	BPIFB2	0.909
SERPINA10	APOA1	0.909
GP1BA	SERPIND1	0.908
CST3	ITIH2	0.908
SERPINA10	APOE	0.908
MATN3	IGFBP4	0.908
C3	IGFBP5	0.908
TF	SERPINA10	0.908
TF	TIMP1	0.908
BPIFB2	TMEM132A	0.907
C4A	LAMB2	0.907
MATN3	BPIFB2	0.907
APLP2	C3	0.907
MATN3	SERPIND1	0.907
NOTUM	FN1	0.907
IGFBP4	C3	0.907
CST3	PROC	0.907
APOA2	TIMP1	0.907
AHSG	IGFBP5	0.907
LAMB2	APLP2	0.907
LAMB2	TIMP1	0.907
C4A	MFI2	0.907
LAMB2	IL6	0.907
AFP	IGFBP5	0.907
LAMB2	MATN3	0.907
LAMB2	C3	0.907
APOA2	IGFBP4	0.907
PCSK9	C3	0.907
GPC3	PCSK9	0.907
C4A	BPIFB2	0.906
FN1	PROC	0.906
CST3	SERPIND1	0.906
ITIH2	IGFBP4	0.906
IGFBP5	APOB	0.906
F8	TIMP1	0.906
APLP2	SERPIND1	0.906
SERPINC1	APLP2	0.906
MATN3	GPC3	0.906
F13A1	PROC	0.906
MATN3	FGA	0.906
MFI2	APOA1	0.906
MATN3	APOA1	0.906
F5	SPP2	0.906
IGFBP5	SERPIND1	0.906
SERPINC1	MFI2	0.906
DNAJC3	SERPINC1	0.906
PCSK9	CP	0.906
NOTUM	MATN3	0.906
NOTUM	PCSK9	0.906
GPC3	IGFBP4	0.906
FN1	TMEM132A	0.906
MATN3	FGG	0.906
DNAJC3	SERPIND1	0.906
TF	SPP2	0.906
FGG	IGFBP5	0.905
CP	SERPINA10	0.905
MATN3	APOA2	0.905
C4A	SPP2	0.905
MATN3	PCSK9	0.905
FGG	TIMP1	0.905
DNAJC3	SERPINA1	0.905
C3	BPIFB2	0.905
PROC	TIMP1	0.905
APOA2	TMEM132A	0.905
GPC3	PROC	0.905
CST3	IGFBP4	0.905
MATN3	ITIH2	0.905
TIMP1	TMEM132A	0.905
LAMB2	CST3	0.905
NOTUM	SERPINC1	0.905
MFI2	TMEM132A	0.905
IGFBP4	PROC	0.905
C4A	APLP2	0.905
MFI2	IGFBP1	0.905
C4A	NOTUM	0.905
MATN3	IGFBP5	0.905
NOTUM	APOE	0.905
FGB	TIMP1	0.905
FGA	TIMP1	0.905
DNAJC3	CP	0.905
PCSK9	SERPINA10	0.905
LAMB2	TMEM132A	0.905
IGFBP1	SPP2	0.904
ITIH2	MFI2	0.904
LAMB2	APOE	0.904
CST3	SPP2	0.904
F5	PCSK9	0.904
LAMB2	GPC3	0.904
PCSK9	KNG1	0.904
DNAJC3	SERPINA10	0.904
FGG	MFI2	0.904
PCSK9	TIMP1	0.904
F5	BPIFB2	0.904
DNAJC3	AHSG	0.904
APOE	SPP2	0.904
DNAJC3	ITIH2	0.904
ITIH2	APOL1	0.904
DNAJC3	FGG	0.904
NOTUM	C3	0.904
FGG	APOL1	0.904
C4A	PCSK9	0.904
LAMB2	APOA1	0.904
AFP	APLP2	0.904
KNG1	IGFBP5	0.904
NOTUM	TF	0.904
SERPINA1	NOTUM	0.904
IGFBP4	BPIFB2	0.904
MATN3	SERPINC1	0.904
MFI2	KNG1	0.904
F5	APOL1	0.904
IGFBP4	SERPINA10	0.904
AFP	SERPINA10	0.904
SERPINC1	IGFBP5	0.904
SERPINA10	TIMP1	0.904
LAMB2	APOL1	0.904
FGA	MFI2	0.903
SERPINA10	IGFBP5	0.903
APOA5	FN1	0.903
DNAJC3	FN1	0.903
MATN3	C3	0.903
CST3	FGG	0.903
IGFBP4	KNG1	0.903
C4A	MATN3	0.903
DNAJC3	PCSK9	0.903
FN1	SPP2	0.903
APLP2	APOA1	0.903
APOA2	MFI2	0.903
MFI2	IGFBP4	0.903
MATN3	PROC	0.903
IGFBP4	APOB	0.903
MATN3	TMEM132A	0.903
FN1	SERPINA10	0.903
GPC3	CP	0.903
AHSG	F8	0.903
IGFBP5	TMEM132A	0.903
ITIH2	TIMP1	0.903
SERPINA1	TMEM132A	0.903
TF	MATN3	0.903
MFI2	APLP2	0.903
APOA2	APLP2	0.903
FN1	BPIFB2	0.903
TF	PCSK9	0.903
APOA2	IGFBP5	0.903
IGFBP1	SERPINA10	0.903
APLP2	TIMP1	0.902
SERPINA1	MFI2	0.902
GPC3	SPP2	0.902
APOE	BPIFB2	0.902
MFI2	PROC	0.902
F5	IGFBP4	0.902
APLP2	SPP2	0.902
MFI2	SPP2	0.902
LAMB2	PCSK9	0.902
FGA	APLP2	0.902
TF	APLP2	0.902
DNAJC3	C3	0.902
MATN3	TIMP1	0.902
IL6	APLP2	0.902
NOTUM	SPP2	0.902
TF	IGFBP5	0.902
IL6	BPIFB2	0.902
MFI2	TIMP1	0.902
F5	MFI2	0.902
PCSK9	BPIFB2	0.902
APOE	TMEM132A	0.902
NOTUM	CP	0.902
LAMB2	CP	0.902
FGG	APLP2	0.902
APOA5	MATN3	0.902
NOTUM	KNG1	0.902
GPC3	C3	0.902
DNAJC3	APOA2	0.902
LAMB2	TF	0.902
IGFBP4	CP	0.902
NOTUM	F5	0.902
AHSG	APLP2	0.902
DNAJC3	APOE	0.902
KNG1	BPIFB2	0.902
APOL1	TIMP1	0.902
APLP2	IGFBP5	0.902
MATN3	SPP2	0.902
PCSK9	SPP2	0.902
CST3	PCSK9	0.902
NOTUM	SERPINA10	0.902
DNAJC3	APOA1	0.902
DNAJC3	IGFBP1	0.902
GPC3	KNG1	0.902
NOTUM	IGFBP4	0.902
GP5	KNG1	0.902
APOA5	IGFBP4	0.902
APLP2	TMEM132A	0.902
IL6	SERPINA10	0.902
DNAJC3	FGA	0.902
DNAJC3	APLP2	0.902
LAMB2	NOTUM	0.902
IGFBP4	SPP2	0.902
CST3	MFI2	0.902
CP	IGFBP5	0.902
MFI2	BPIFB2	0.902
IGFBP5	BPIFB2	0.902
DNAJC3	LAMB2	0.902
CST3	TMEM132A	0.902
DNAJC3	CST3	0.902
IL6	ITIH2	0.901
DNAJC3	MATN3	0.901
MFI2	IGFBP5	0.901
F5	APLP2	0.901
MATN3	APLP2	0.901
SERPINA1	LAMB2	0.901
CP	TMEM132A	0.901
TIMP1	SPP2	0.901
DNAJC3	C4A	0.901
DNAJC3	KNG1	0.901
APOA1	TMEM132A	0.901
IGFBP1	APLP2	0.901
APOL1	IGFBP5	0.901
C3	TMEM132A	0.901
PCSK9	IGFBP5	0.901
APOL1	APLP2	0.901
APOL1	SERPINA10	0.901
GPC3	MFI2	0.901
NOTUM	APLP2	0.901
IGFBP4	APLP2	0.901
LAMB2	BPIFB2	0.901
C4A	GPC3	0.901
IGFBP1	TMEM132A	0.9
MATN3	F5	0.9
DNAJC3	APOL1	0.9
SERPINC1	TMEM132A	0.9
NOTUM	IL6	0.9
MATN3	APOE	0.9
NOTUM	APOL1	0.9
SERPINA1	MATN3	0.9
APOB	TMEM132A	0.9
LAMB2	SERPINA10	0.9
F5	TMEM132A	0.9
APOL1	IGFBP4	0.9
CST3	F5	0.9
SERPINA10	TMEM132A	0.9
GPC3	APLP2	0.9
NOTUM	IGFBP5	0.9
AHSG	LAMB2	0.9
APOA5	APLP2	0.9
FGA	TMEM132A	0.9
GPC3	F5	0.9
LAMB2	SPP2	0.9
DNAJC3	TF	0.9
APLP2	SERPINA10	0.9
APOA5	CST3	0.9
APOA5	IGFBP5	0.9
GP5	PROC	0.9
DNAJC3	MFI2	0.9
MATN3	CST3	0.9
MATN3	APOL1	0.9
APOA5	TIMP1	0.9
APOL1	BPIFB2	0.9
LAMB2	SERPINC1	0.9
F5	IGFBP5	0.9
LAMB2	APOA2	0.9
KNG1	TMEM132A	0.9
DNAJC3	SPP2	0.9
AFP	TMEM132A	0.9
DNAJC3	TIMP1	0.9
ITIH2	IGFBP5	0.9
DNAJC3	BPIFB2	0.9
ALB	TMEM132A	0.9
DNAJC3	IGFBP4	0.9
BPIFB2	SPP2	0.9
LAMB2	F5	0.9
APOL1	IGFBP1	0.9
DNAJC3	GPC3	0.9
DNAJC3	APOA5	0.9
MATN3	MFI2	0.9
PCSK9	TMEM132A	0.9
C4A	TMEM132A	0.9
LAMB2	APOB	0.9
CST3	SERPINA10	0.9
APOL1	PROC	0.9
NOTUM	CST3	0.9
APLP2	PROC	0.9
IGFBP5	SPP2	0.9
DNAJC3	F5	0.9
LAMB2	FGA	0.9
DNAJC3	PROC	0.9
LAMB2	AFP	0.9
NOTUM	TMEM132A	0.9
APOA5	LAMB2	0.9
APLP2	BPIFB2	0.9
DNAJC3	TMEM132A	0.9
LAMB2	IGFBP1	0.9
DNAJC3	IGFBP5	0.9
IL6	TMEM132A	0.9
PROC	TMEM132A	0.9
LAMB2	MFI2	0.9
FGG	TMEM132A	0.9
MATN3	CP	0.9
TIMP1	BPIFB2	0.9
APOL1	SPP2	0.9
LAMB2	ITIH2	0.9
SPP2	TMEM132A	0.9
DNAJC3	AFP	0.9
GPC3	APOL1	0.9
MATN3	KNG1	0.9
NOTUM	MFI2	0.9
PCSK9	MFI2	0.9
SERPINA1	APLP2	0.9
SERPINA10	BPIFB2	0.9
APOL1	MFI2	0.9
NOTUM	TIMP1	0.9
IL6	SPP2	0.9
LAMB2	PROC	0.9
DNAJC3	NOTUM	0.9
GPC3	TMEM132A	0.9
GP5	F10	0.9
F5	TIMP1	0.9
APOL1	TMEM132A	0.9
TF	IGFBP4	0.9
CST3	GPC3	0.9
MATN3	SERPINA10	0.9
LAMB2	KNG1	0.9
LAMB2	FGG	0.9
APOA5	TMEM132A	0.9
AHSG	TMEM132A	0.9
PROC	IGFBP5	0.9
FGA	IGFBP5	0.9

Gene Ontology Semantic Similarity

Download Tab separated file

#	2243 (FGA)	2266 (FGG)	335 (APOA1)	336 (APOA2)	197 (AHSG)	462 (SERPINC1)	2157 (F8)	348 (APOE)	255738 (PCSK9)	2147 (F2)	213 (ALB)	174 (AFP)	3698 (ITIH2)	2335 (FN1)	2160 (F11)	2159 (F10)	5265 (SERPINA1)	3569 (IL6)	2811 (GP1BA)	7018 (TF)	116519 (APOA5)	2153 (F5)	1471 (CST3)	2814 (GP5)	3484 (IGFBP1)	8542 (APOL1)	2244 (FGB)	718 (C3)	51156 (SERPINA10)	338 (APOB)	1356 (CP)	5624 (PROC)	147111 (NOTUM)	720 (C4A)	3827 (KNG1)	2162 (F13A1)	2719 (GPC3)	7450 (VWF)	4148 (MATN3)	334 (APLP2)	3487 (IGFBP4)	3913 (LAMB2)	7076 (TIMP1)	4241 (MFI2)	3488 (IGFBP5)	3053 (SERPIND1)	5611 (DNAJC3)	6694 (SPP2)	54972 (TMEM132A)
2243 (FGA)	1.00	1.00	0.62	0.54	0.20	0.66	1.00	0.62	0.60	0.61	0.60	1.00	0.16	0.77	0.63	0.60	0.66	0.73	0.63	0.63	0.47	1.00	0.59	1.00	0.73	0.62	0.98	0.69	0.15	0.60	0.49	0.63	0.16	0.39	0.62	0.21	0.63	0.80	0.91	0.68	0.74	0.70	0.59	0.65	0.70	0.14	0.58	0.16	0.64
2266 (FGG)	1.00	1.00	0.62	0.54	0.20	0.66	1.00	0.62	0.60	0.61	0.60	1.00	0.16	0.77	0.63	0.60	0.66	0.73	0.63	0.63	0.47	1.00	0.59	1.00	0.73	0.62	0.98	0.69	0.15	0.60	0.49	0.63	0.16	0.39	0.62	0.21	0.63	0.80	0.91	0.68	0.74	0.70	0.59	0.65	0.70	0.14	0.58	0.16	0.64
335 (APOA1)	0.62	0.62	1.00	0.84	0.42	0.62	1.00	0.80	0.60	0.58	0.61	1.00	0.33	0.65	0.55	0.62	0.62	0.59	0.55	0.55	0.79	1.00	0.66	1.00	0.62	0.59	0.63	0.59	0.30	0.73	0.44	0.55	0.12	0.34	0.60	0.21	0.58	0.64	0.56	0.60	0.62	0.27	0.58	0.56	0.59	0.14	0.53	0.33	0.64
336 (APOA2)	0.54	0.54	0.84	1.00	0.63	0.55	1.00	0.80	0.58	0.53	0.55	1.00	0.50	0.57	0.48	0.57	0.55	0.52	0.48	0.49	0.81	1.00	0.55	1.00	0.55	0.57	0.55	0.51	0.46	0.69	0.38	0.48	0.11	0.29	0.55	0.16	0.54	0.58	0.49	0.52	0.54	0.24	0.55	0.49	0.53	0.17	0.49	0.50	0.48
197 (AHSG)	0.20	0.20	0.42	0.63	1.00	0.42	0.16	0.42	0.29	0.16	0.20	0.16	0.46	0.16	0.16	0.16	0.42	0.16	0.16	0.16	0.49	0.16	0.46	0.16	0.16	0.16	0.20	0.16	0.42	0.16	0.13	0.16	0.09	0.10	0.42	0.09	0.50	0.16	0.16	0.16	0.16	0.20	0.57	0.16	0.16	0.46	0.81	0.46	0.27
462 (SERPINC1)	0.66	0.66	0.62	0.55	0.42	1.00	1.00	0.55	0.57	0.56	0.60	1.00	0.90	0.69	0.62	0.59	1.00	0.69	0.62	0.61	0.48	1.00	0.90	1.00	0.70	0.61	0.67	0.64	1.00	0.58	0.47	0.62	0.12	0.39	0.73	0.16	0.80	0.75	0.65	0.74	0.71	0.27	0.80	0.66	0.71	0.54	0.64	0.90	0.48
2157 (F8)	1.00	1.00	1.00	1.00	0.16	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.13	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.82	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.12	1.00	0.82	1.00	0.16	0.61	1.00	0.16	1.00	1.00	1.00	1.00	1.00	0.34	1.00	1.00	1.00	0.13	0.82	0.13	0.48
348 (APOE)	0.62	0.62	0.80	0.80	0.42	0.55	1.00	1.00	0.58	0.58	0.63	1.00	0.33	0.64	0.50	0.56	0.55	0.53	0.50	0.53	0.79	1.00	0.59	1.00	0.55	0.57	0.63	0.52	0.30	0.73	0.40	0.50	0.13	0.30	0.60	0.21	0.52	0.63	0.55	0.55	0.55	0.35	0.54	0.53	0.54	0.13	0.46	0.33	0.64
255738 (PCSK9)	0.60	0.60	0.60	0.58	0.29	0.57	1.00	0.58	1.00	0.64	0.58	1.00	0.23	0.59	0.66	0.64	0.57	0.58	0.53	0.54	0.51	1.00	0.54	1.00	0.62	0.53	0.61	0.69	0.22	0.58	0.43	0.66	0.14	0.46	0.56	0.16	0.55	0.60	0.54	0.62	0.61	0.24	0.54	0.55	0.58	0.12	0.50	0.23	0.48
2147 (F2)	0.61	0.61	0.58	0.53	0.16	0.56	1.00	0.58	0.64	1.00	0.56	1.00	0.13	0.69	0.71	0.72	0.56	0.67	0.60	0.55	0.54	1.00	0.52	1.00	0.65	0.56	0.63	0.76	0.12	0.64	0.42	0.71	0.16	0.52	0.67	0.16	0.52	0.61	0.53	0.57	0.64	0.25	0.51	0.54	0.60	0.10	0.51	0.13	0.48
213 (ALB)	0.60	0.60	0.61	0.55	0.20	0.60	1.00	0.63	0.58	0.56	1.00	1.00	0.16	0.64	0.55	0.59	0.60	0.60	0.55	0.62	0.50	1.00	0.57	1.00	0.61	0.57	0.63	0.57	0.15	0.59	0.48	0.55	0.14	0.34	0.62	0.21	0.56	0.65	0.57	0.72	0.60	0.30	0.58	0.63	0.60	0.12	0.54	0.16	0.64
174 (AFP)	1.00	1.00	1.00	1.00	0.16	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.13	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.82	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.12	1.00	0.82	1.00	0.16	0.61	1.00	0.16	1.00	1.00	1.00	1.00	1.00	0.34	1.00	1.00	1.00	0.13	0.82	0.13	0.48
3698 (ITIH2)	0.16	0.16	0.33	0.50	0.46	0.90	0.13	0.33	0.23	0.13	0.16	0.13	1.00	0.13	0.13	0.13	0.90	0.13	0.13	0.13	0.40	0.13	1.00	0.13	0.13	0.13	0.16	0.13	0.90	0.13	0.10	0.13	0.07	0.08	0.90	0.07	0.70	0.13	0.13	0.13	0.13	0.16	0.81	0.13	0.13	1.00	0.37	1.00	0.22
2335 (FN1)	0.77	0.77	0.65	0.57	0.16	0.69	1.00	0.64	0.59	0.69	0.64	1.00	0.13	1.00	0.61	0.62	0.69	0.68	0.61	0.62	0.57	1.00	0.65	1.00	0.69	0.61	0.79	0.66	0.12	0.69	0.52	0.61	0.11	0.38	0.70	0.16	0.61	0.87	0.73	0.67	0.69	0.38	0.63	0.63	0.66	0.10	0.59	0.13	0.48
2160 (F11)	0.63	0.63	0.55	0.48	0.16	0.62	1.00	0.50	0.66	0.71	0.55	1.00	0.13	0.61	1.00	0.88	0.62	0.67	0.56	0.57	0.40	1.00	0.54	1.00	0.69	0.56	0.65	0.89	0.12	0.53	0.45	1.00	0.22	0.80	0.53	0.16	0.57	0.66	0.60	0.66	0.69	0.27	0.51	0.61	0.69	0.11	0.58	0.13	0.48
2159 (F10)	0.60	0.60	0.62	0.57	0.16	0.59	1.00	0.56	0.64	0.72	0.59	1.00	0.13	0.62	0.88	1.00	0.59	0.63	0.52	0.54	0.51	1.00	0.52	1.00	0.65	0.58	0.62	0.82	0.12	0.68	0.42	0.88	0.20	0.69	0.55	0.16	0.53	0.63	0.55	0.61	0.65	0.26	0.50	0.57	0.65	0.11	0.55	0.13	0.48
5265 (SERPINA1)	0.66	0.66	0.62	0.55	0.42	1.00	1.00	0.55	0.57	0.56	0.60	1.00	0.90	0.69	0.62	0.59	1.00	0.69	0.62	0.61	0.48	1.00	0.90	1.00	0.70	0.61	0.67	0.64	1.00	0.58	0.47	0.62	0.12	0.39	0.73	0.16	0.80	0.75	0.65	0.74	0.71	0.27	0.80	0.66	0.71	0.54	0.64	0.90	0.48
3569 (IL6)	0.73	0.73	0.59	0.52	0.16	0.69	1.00	0.53	0.58	0.67	0.60	1.00	0.13	0.68	0.67	0.63	0.69	1.00	0.67	0.66	0.46	1.00	0.61	1.00	0.79	0.66	0.74	0.73	0.12	0.61	0.51	0.67	0.12	0.42	0.66	0.16	0.68	0.69	0.70	0.73	0.80	0.27	0.65	0.71	0.74	0.10	0.62	0.13	0.48
2811 (GP1BA)	0.63	0.63	0.55	0.48	0.16	0.62	1.00	0.50	0.53	0.60	0.55	1.00	0.13	0.61	0.56	0.52	0.62	0.67	1.00	0.57	0.40	1.00	0.53	1.00	0.69	0.56	0.65	0.60	0.12	0.53	0.42	0.56	0.13	0.35	0.53	0.16	0.56	0.66	0.59	0.66	0.69	0.27	0.51	0.61	0.69	0.11	0.58	0.13	0.48
7018 (TF)	0.63	0.63	0.55	0.49	0.16	0.61	1.00	0.53	0.54	0.55	0.62	1.00	0.13	0.62	0.57	0.54	0.61	0.66	0.57	1.00	0.43	1.00	0.54	1.00	0.69	0.57	0.65	0.62	0.12	0.54	0.43	0.57	0.12	0.35	0.67	0.16	0.57	0.65	0.59	0.64	0.69	0.26	0.63	0.88	0.66	0.10	0.56	0.13	0.48
116519 (APOA5)	0.47	0.47	0.79	0.81	0.49	0.48	0.82	0.79	0.51	0.54	0.50	0.82	0.40	0.57	0.40	0.51	0.48	0.46	0.40	0.43	1.00	0.82	0.48	0.82	0.47	0.50	0.48	0.45	0.37	0.74	0.32	0.40	0.11	0.25	0.56	0.16	0.47	0.48	0.41	0.43	0.47	0.23	0.50	0.42	0.44	0.18	0.44	0.40	0.48
2153 (F5)	1.00	1.00	1.00	1.00	0.16	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.13	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.82	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.12	1.00	0.82	1.00	0.16	0.61	1.00	0.16	1.00	1.00	1.00	1.00	1.00	0.34	1.00	1.00	1.00	0.13	0.82	0.13	0.48
1471 (CST3)	0.59	0.59	0.66	0.55	0.46	0.90	1.00	0.59	0.54	0.52	0.57	1.00	1.00	0.65	0.54	0.52	0.90	0.61	0.53	0.54	0.48	1.00	1.00	1.00	0.62	0.54	0.61	0.56	0.90	0.53	0.42	0.54	0.11	0.33	0.75	0.16	0.74	0.69	0.55	0.64	0.62	0.25	0.78	0.56	0.62	0.53	0.59	1.00	0.48
2814 (GP5)	1.00	1.00	1.00	1.00	0.16	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.13	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.82	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.12	1.00	0.82	1.00	0.16	0.61	1.00	0.16	1.00	1.00	1.00	1.00	1.00	0.34	1.00	1.00	1.00	0.13	0.82	0.13	0.48
3484 (IGFBP1)	0.73	0.73	0.62	0.55	0.16	0.70	1.00	0.55	0.62	0.65	0.61	1.00	0.13	0.69	0.69	0.65	0.70	0.79	0.69	0.69	0.47	1.00	0.62	1.00	1.00	0.67	0.74	0.74	0.12	0.63	0.52	0.69	0.12	0.42	0.66	0.16	0.69	0.71	0.71	0.74	0.98	0.27	0.62	0.72	0.94	0.10	0.62	0.13	0.48
8542 (APOL1)	0.62	0.62	0.59	0.57	0.16	0.61	1.00	0.57	0.53	0.56	0.57	1.00	0.13	0.61	0.56	0.58	0.61	0.66	0.56	0.57	0.50	1.00	0.54	1.00	0.67	1.00	0.64	0.59	0.12	0.58	0.43	0.56	0.13	0.35	0.53	0.16	0.56	0.65	0.59	0.64	0.67	0.28	0.52	0.60	0.67	0.11	0.57	0.13	0.48
2244 (FGB)	0.98	0.98	0.63	0.55	0.20	0.67	1.00	0.63	0.61	0.63	0.63	1.00	0.16	0.79	0.65	0.62	0.67	0.74	0.65	0.65	0.48	1.00	0.61	1.00	0.74	0.64	1.00	0.70	0.15	0.61	0.57	0.65	0.16	0.40	0.64	0.21	0.65	0.82	0.90	0.69	0.74	0.65	0.61	0.67	0.71	0.13	0.64	0.16	0.64
718 (C3)	0.69	0.69	0.59	0.51	0.16	0.64	1.00	0.52	0.69	0.76	0.57	1.00	0.13	0.66	0.89	0.82	0.64	0.73	0.60	0.62	0.45	1.00	0.56	1.00	0.74	0.59	0.70	1.00	0.12	0.57	0.47	0.89	0.18	0.67	0.61	0.16	0.60	0.67	0.62	0.67	0.75	0.26	0.56	0.63	0.69	0.10	0.58	0.13	0.48
51156 (SERPINA10)	0.15	0.15	0.30	0.46	0.42	1.00	0.12	0.30	0.22	0.12	0.15	0.12	0.90	0.12	0.12	0.12	1.00	0.12	0.12	0.12	0.37	0.12	0.90	0.12	0.12	0.12	0.15	0.12	1.00	0.12	0.10	0.12	0.07	0.07	0.80	0.07	0.64	0.12	0.12	0.12	0.12	0.15	0.74	0.12	0.12	1.00	0.33	0.90	0.21
338 (APOB)	0.60	0.60	0.73	0.69	0.16	0.58	1.00	0.73	0.58	0.64	0.59	1.00	0.13	0.69	0.53	0.68	0.58	0.61	0.53	0.54	0.74	1.00	0.53	1.00	0.63	0.58	0.61	0.57	0.12	1.00	0.42	0.53	0.11	0.33	0.67	0.16	0.54	0.62	0.55	0.59	0.63	0.25	0.51	0.56	0.62	0.10	0.53	0.13	0.48
1356 (CP)	0.49	0.49	0.44	0.38	0.13	0.47	0.82	0.40	0.43	0.42	0.48	0.82	0.10	0.52	0.45	0.42	0.47	0.51	0.42	0.43	0.32	0.82	0.42	0.82	0.52	0.43	0.57	0.47	0.10	0.42	1.00	0.45	0.22	0.32	0.41	0.28	0.42	0.55	0.44	0.49	0.52	0.25	0.40	0.45	0.52	0.10	0.53	0.10	0.38
5624 (PROC)	0.63	0.63	0.55	0.48	0.16	0.62	1.00	0.50	0.66	0.71	0.55	1.00	0.13	0.61	1.00	0.88	0.62	0.67	0.56	0.57	0.40	1.00	0.54	1.00	0.69	0.56	0.65	0.89	0.12	0.53	0.45	1.00	0.22	0.80	0.53	0.16	0.57	0.66	0.60	0.66	0.69	0.27	0.51	0.61	0.69	0.11	0.58	0.13	0.48
147111 (NOTUM)	0.16	0.16	0.12	0.11	0.09	0.12	0.16	0.13	0.14	0.16	0.14	0.16	0.07	0.11	0.22	0.20	0.12	0.12	0.13	0.12	0.11	0.16	0.11	0.16	0.12	0.13	0.16	0.18	0.07	0.11	0.22	0.22	1.00	0.21	0.11	0.20	0.13	0.12	0.15	0.13	0.12	0.18	0.11	0.13	0.12	0.07	0.11	0.07	0.28
720 (C4A)	0.39	0.39	0.34	0.29	0.10	0.39	0.61	0.30	0.46	0.52	0.34	0.61	0.08	0.38	0.80	0.69	0.39	0.42	0.35	0.35	0.25	0.61	0.33	0.61	0.42	0.35	0.40	0.67	0.07	0.33	0.32	0.80	0.21	1.00	0.33	0.16	0.36	0.40	0.37	0.41	0.42	0.18	0.31	0.38	0.42	0.07	0.36	0.08	0.27
3827 (KNG1)	0.62	0.62	0.60	0.55	0.42	0.73	1.00	0.60	0.56	0.67	0.62	1.00	0.90	0.70	0.53	0.55	0.73	0.66	0.53	0.67	0.56	1.00	0.75	1.00	0.66	0.53	0.64	0.61	0.80	0.67	0.41	0.53	0.11	0.33	1.00	0.16	0.67	0.63	0.55	0.59	0.66	0.25	0.81	0.68	0.62	0.43	0.57	0.90	0.48
2162 (F13A1)	0.21	0.21	0.21	0.16	0.09	0.16	0.16	0.21	0.16	0.16	0.21	0.16	0.07	0.16	0.16	0.16	0.16	0.16	0.16	0.16	0.16	0.16	0.16	0.16	0.16	0.16	0.21	0.16	0.07	0.16	0.28	0.16	0.20	0.16	0.16	1.00	0.16	0.16	0.16	0.16	0.16	0.21	0.16	0.16	0.16	0.07	0.13	0.07	0.28
2719 (GPC3)	0.63	0.63	0.58	0.54	0.50	0.80	1.00	0.52	0.55	0.52	0.56	1.00	0.70	0.61	0.57	0.53	0.80	0.68	0.56	0.57	0.47	1.00	0.74	1.00	0.69	0.56	0.65	0.60	0.64	0.54	0.42	0.57	0.13	0.36	0.67	0.16	1.00	0.66	0.60	0.67	0.69	0.28	0.75	0.62	0.69	0.54	0.67	0.70	0.48
7450 (VWF)	0.80	0.80	0.64	0.58	0.16	0.75	1.00	0.63	0.60	0.61	0.65	1.00	0.13	0.87	0.66	0.63	0.75	0.69	0.66	0.65	0.48	1.00	0.69	1.00	0.71	0.65	0.82	0.67	0.12	0.62	0.55	0.66	0.12	0.40	0.63	0.16	0.66	1.00	0.79	0.73	0.71	0.41	0.65	0.67	0.70	0.10	0.62	0.13	0.48
4148 (MATN3)	0.91	0.91	0.56	0.49	0.16	0.65	1.00	0.55	0.54	0.53	0.57	1.00	0.13	0.73	0.60	0.55	0.65	0.70	0.59	0.59	0.41	1.00	0.55	1.00	0.71	0.59	0.90	0.62	0.12	0.55	0.44	0.60	0.15	0.37	0.55	0.16	0.60	0.79	1.00	0.69	0.71	0.78	0.53	0.65	0.71	0.13	0.60	0.13	0.48
334 (APLP2)	0.68	0.68	0.60	0.52	0.16	0.74	1.00	0.55	0.62	0.57	0.72	1.00	0.13	0.67	0.66	0.61	0.74	0.73	0.66	0.64	0.43	1.00	0.64	1.00	0.74	0.64	0.69	0.67	0.12	0.59	0.49	0.66	0.13	0.41	0.59	0.16	0.67	0.73	0.69	1.00	0.74	0.29	0.57	0.70	0.74	0.11	0.62	0.13	0.48
3487 (IGFBP4)	0.74	0.74	0.62	0.54	0.16	0.71	1.00	0.55	0.61	0.64	0.60	1.00	0.13	0.69	0.69	0.65	0.71	0.80	0.69	0.69	0.47	1.00	0.62	1.00	0.98	0.67	0.74	0.75	0.12	0.63	0.52	0.69	0.12	0.42	0.66	0.16	0.69	0.71	0.71	0.74	1.00	0.27	0.62	0.72	0.95	0.11	0.62	0.13	0.48
3913 (LAMB2)	0.70	0.70	0.27	0.24	0.20	0.27	0.34	0.35	0.24	0.25	0.30	0.34	0.16	0.38	0.27	0.26	0.27	0.27	0.27	0.26	0.23	0.34	0.25	0.34	0.27	0.28	0.65	0.26	0.15	0.25	0.25	0.27	0.18	0.18	0.25	0.21	0.28	0.41	0.78	0.29	0.27	1.00	0.24	0.28	0.27	0.15	0.24	0.16	0.64
7076 (TIMP1)	0.59	0.59	0.58	0.55	0.57	0.80	1.00	0.54	0.54	0.51	0.58	1.00	0.81	0.63	0.51	0.50	0.80	0.65	0.51	0.63	0.50	1.00	0.78	1.00	0.62	0.52	0.61	0.56	0.74	0.51	0.40	0.51	0.11	0.31	0.81	0.16	0.75	0.65	0.53	0.57	0.62	0.24	1.00	0.64	0.60	0.44	0.59	0.81	0.48
4241 (MFI2)	0.65	0.65	0.56	0.49	0.16	0.66	1.00	0.53	0.55	0.54	0.63	1.00	0.13	0.63	0.61	0.57	0.66	0.71	0.61	0.88	0.42	1.00	0.56	1.00	0.72	0.60	0.67	0.63	0.12	0.56	0.45	0.61	0.13	0.38	0.68	0.16	0.62	0.67	0.65	0.70	0.72	0.28	0.64	1.00	0.72	0.11	0.61	0.13	0.48
3488 (IGFBP5)	0.70	0.70	0.59	0.53	0.16	0.71	1.00	0.54	0.58	0.60	0.60	1.00	0.13	0.66	0.69	0.65	0.71	0.74	0.69	0.66	0.44	1.00	0.62	1.00	0.94	0.67	0.71	0.69	0.12	0.62	0.52	0.69	0.12	0.42	0.62	0.16	0.69	0.70	0.71	0.74	0.95	0.27	0.60	0.72	1.00	0.11	0.62	0.13	0.48
3053 (SERPIND1)	0.14	0.14	0.14	0.17	0.46	0.54	0.13	0.13	0.12	0.10	0.12	0.13	1.00	0.10	0.11	0.11	0.54	0.10	0.11	0.10	0.18	0.13	0.53	0.13	0.10	0.11	0.13	0.10	1.00	0.10	0.10	0.11	0.07	0.07	0.43	0.07	0.54	0.10	0.13	0.11	0.11	0.15	0.44	0.11	0.11	1.00	0.21	1.00	0.22
5611 (DNAJC3)	0.58	0.58	0.53	0.49	0.81	0.64	0.82	0.46	0.50	0.51	0.54	0.82	0.37	0.59	0.58	0.55	0.64	0.62	0.58	0.56	0.44	0.82	0.59	0.82	0.62	0.57	0.64	0.58	0.33	0.53	0.53	0.58	0.11	0.36	0.57	0.13	0.67	0.62	0.60	0.62	0.62	0.24	0.59	0.61	0.62	0.21	1.00	0.37	0.38
6694 (SPP2)	0.16	0.16	0.33	0.50	0.46	0.90	0.13	0.33	0.23	0.13	0.16	0.13	1.00	0.13	0.13	0.13	0.90	0.13	0.13	0.13	0.40	0.13	1.00	0.13	0.13	0.13	0.16	0.13	0.90	0.13	0.10	0.13	0.07	0.08	0.90	0.07	0.70	0.13	0.13	0.13	0.13	0.16	0.81	0.13	0.13	1.00	0.37	1.00	0.22
54972 (TMEM132A)	0.64	0.64	0.64	0.48	0.27	0.48	0.48	0.64	0.48	0.48	0.64	0.48	0.22	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.64	0.48	0.21	0.48	0.38	0.48	0.28	0.27	0.48	0.28	0.48	0.48	0.48	0.48	0.48	0.64	0.48	0.48	0.48	0.22	0.38	0.22	1.00

Association with High Altitude

Protein Official symbol	Source Organism	Tissue of Expression	Level of hypoxia	Altitude	Duration of experiment	Level of expression	Fold change	Experiment details	geographical location	ethnicity of the patients	Control group	Control (Fold change)	Reference (PMID)
SERPIND1	Human	Blood	-	3600 m	Native	downregulated	-	TMT-based proteomic analysis/LC-MS	Central Asia	Tibetans	-	High altitude native vs. low Lander	30908922

Association with TF

TF	TF Entrez	Gene	Gene Entrez	Type	PMID	Database
CEBPB	1051	SERPIND1	3053	distal	22955619	TRANSFAC
E2F6	1876	SERPIND1	3053	distal	22955619	TRANSFAC
FOS	2353	SERPIND1	3053	distal	22955619	TRANSFAC
NFYA	4800	SERPIND1	3053	distal	22955619	TRANSFAC
GABPA	2551	SERPIND1	3053	distal	22955619	TRANSFAC
JUN	3725	SERPIND1	3053	distal	22955619	TRANSFAC
RAD21	5885	SERPIND1	3053	distal	22955619	TRANSFAC
CTCFL	140690	SERPIND1	3053	distal	22955619	TRANSFAC
EGR1	1958	SERPIND1	3053	distal	22955619	TRANSFAC
CTCF	10664	SERPIND1	3053	distal	22955619	TRANSFAC
JUND	3727	SERPIND1	3053	distal	22955619	TRANSFAC
USF1	7391	SERPIND1	3053	distal	22955619	TRANSFAC
EP300	2033	SERPIND1	3053	distal	22955619	TRANSFAC
JUNB	3726	SERPIND1	3053	distal	22955619	TRANSFAC
NFYB	4801	SERPIND1	3053	distal	22955619	TRANSFAC
SPI1	6688	SERPIND1	3053	distal	22955619	TRANSFAC
MAFK	7975	SERPIND1	3053	proximal_filtered	22955619	TRANSFAC
MAFF	23764	SERPIND1	3053	proximal_filtered	22955619	TRANSFAC
FOXA1	3169	SERPIND1	3053	proximal_filtered	22955619	TRANSFAC
XRCC4	7518	SERPIND1	3053	proximal_filtered	22955619	TRANSFAC
FOSL1	8061	SERPIND1	3053	proximal_filtered	22955619	TRANSFAC
BDP1	55814	SERPIND1	3053	proximal_filtered	22955619	TRANSFAC
SIRT6	51548	SERPIND1	3053	proximal_filtered	22955619	TRANSFAC
BRF1	2972	SERPIND1	3053	proximal_filtered	22955619	TRANSFAC
HDAC2	3066	SERPIND1	3053	proximal_filtered	22955619	TRANSFAC
FOXA2	3170	SERPIND1	3053	proximal_filtered	22955619	TRANSFAC
SETDB1	9869	SERPIND1	3053	proximal_filtered	22955619	TRANSFAC
GATA2	2624	SERPIND1	3053	proximal_filtered	22955619	TRANSFAC
ZNF274	10782	SERPIND1	3053	proximal_filtered	22955619	TRANSFAC
BRF2	55290	SERPIND1	3053	proximal_filtered	22955619	TRANSFAC

Association with miRNA

miRTarBase ID	miRNA	Species (miRNA)	Protein Official Symbol	Human Entrez ID	Species (Target Gene)	Experiments	Support Type	References (PMID)
MIRT018769	hsa-miR-335-5p	Homo sapiens	SERPIND1	3053	Homo sapiens	Microarray	Functional MTI (Weak)	18185580

Gene Ontology

ID	GO ID	GO Term	GO Type
3053	GO:0007596	blood coagulation	GOTERM_BP_DIRECT
3053	GO:0005615	extracellular space	GOTERM_CC_DIRECT
3053	GO:0008218	bioluminescence	GOTERM_BP_DIRECT
3053	GO:0008201	heparin binding	GOTERM_MF_DIRECT
3053	GO:0005576	extracellular region	GOTERM_CC_DIRECT
3053	GO:0010951	negative regulation of endopeptidase activity	GOTERM_BP_DIRECT
3053	GO:0004866	endopeptidase inhibitor activity	GOTERM_MF_DIRECT
3053	GO:0070062	extracellular exosome	GOTERM_CC_DIRECT
3053	GO:0006935	chemotaxis	GOTERM_BP_DIRECT
3053	GO:0004867	serine-type endopeptidase inhibitor activity	GOTERM_MF_DIRECT

Pathways

Human Entrez ID	KEGG ID	KEGG Term
3053	hsa04610	Complement and coagulation cascades

Association with Disease

Protein Official Symbol	Human Entrez ID	Disease Name	Disease Id	Disease Semantic Type	Semantic score	DSI	DPI	Disease Type
SERPIND1	3053	Internal Carotid Artery Thrombosis	C0750990	Disease or Syndrome	0.3	0.659	0.379	disease
SERPIND1	3053	Venous Thromboembolism	C1861172	Disease or Syndrome	0.3	0.659	0.379	phenotype
SERPIND1	3053	Mesenteric Vascular Occlusion	C0025472	Disease or Syndrome	0.3	0.659	0.379	disease
SERPIND1	3053	Common Carotid Artery Thrombosis	C0750988	Disease or Syndrome	0.3	0.659	0.379	disease
SERPIND1	3053	Carotid Artery Thrombosis	C0007274	Disease or Syndrome	0.3	0.659	0.379	disease
SERPIND1	3053	Thrombophilia	C0398623	Disease or Syndrome	0.31	0.659	0.379	disease
SERPIND1	3053	External Carotid Artery Thrombosis	C0750989	Disease or Syndrome	0.3	0.659	0.379	disease
SERPIND1	3053	Heparin cofactor II deficiency (disorder)	C0398626	Disease or Syndrome	0.6	0.659	0.379	disease

Association with Drug

Protein Official Symbol	Human Entrez ID	drug_claim_primary_name	drug_name	drug_chembl_id	interaction_types
SERPIND1	3053	ARDEPARIN	ARDEPARIN SODIUM	CHEMBL1201448	None
SERPIND1	3053	ARDEPARIN	None	None	binder
SERPIND1	3053	ARDEPARIN	ARDEPARIN SODIUM	CHEMBL1201448	None
SERPIND1	3053	SULODEXIDE	SULODEXIDE	CHEMBL2108086	None
SERPIND1	3053	SULODEXIDE	SULODEXIDE	CHEMBL2108086	None