ALTITUDEOMICSDB

Serum albumin

AltitudeomicsDB

Protein Official symbol	ALB
Aliases	ALB GIG20 GIG42 PRO0903 PRO1708 PRO2044 PRO2619 PRO2675 UNQ696/PRO1341
Chromosomal Location	4
Length	609
Uniprot ID	P02768
EC number	None
Protein family Information(Pfam)	PF00273;
PDB id	1AO6;1BJ5;1BKE;1BM0;1E78;1E7A;1E7B;1E7C;1E7E;1E7F;1E7G;1E7H;1E7I;1GNI;1GNJ;1H9Z;1HA2;1HK1;1HK2;1HK3;1HK4;1HK5;1N5U;1O9X;1TF0;1UOR;1YSX;2BX8;2BXA;2BXB;2BXC;2BXD;2BXE;2BXF;2BXG;2BXH;2BXI;2BXK;2BXL;2BXM;2BXN;2BXO;2BXP;2BXQ;2ESG;2I2Z;2I30;2N0X;2VDB;2VUE;2VUF;2XSI;2XVQ;2XVU;2XVV;2XVW;2XW0;2XW1;2YDF;3A73;3B9L;3B9M;3CX9;3JQZ;3JRY;3LU6;3LU7;3LU8;3SQJ;3TDL;3UIV;4BKE;4E99;4EMX;4G03;4G04;4HGK;4HGM;4IW1;4IW2;4K2C;4K71;4L8U;4L9K;4L9Q;4LA0;4LB2;4LB9;4N0F;4N0U;4S1Y;4Z69;5FUO;5GIX;5GIY;5ID7;5IFO;5IJF;5UJB;5VNW;5X52;5YB1;5YOQ;5Z0B;6A7P;6EZQ;6HSC;6JE7;6QIO;6QIP;6XV0;
InterPro ID	IPR000264;IPR020858;IPR021177;IPR020857;IPR014760;
dbSNP	rs80008208 rs72552709 rs74821926 rs74821926 rs74821926 rs75353611 rs76285851 rs141733599 rs77050410 rs78574148 rs77892378 rs80296402 rs77238412 rs75522063 rs77752336 rs80095457 rs77656691 rs3210154 rs3204504 rs3210163 rs75002628 rs75002628 rs79804069 rs79377490 rs80002911 rs79744198 rs74718349 rs72552710 rs76242087 rs76242087 rs77544362 rs78953271 rs72552711 rs77354753 rs76593094 rs75791663 rs75069738 rs77187142 rs78538497 rs78166690 rs77514449 rs79047363 rs79047363 rs76483862 rs78575701 rs1063469 rs80259813 rs75920790 rs75523493 rs74826639 rs78284052 rs77645174 rs80345158 rs79738788 rs79738788 rs76671808 rs76587671 rs75709682 rs79228041 rs80106970 rs75738598

Protein Protein Interaction

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AltitudeomicsDB

Protein 1	Protein 2	Combine Score
TKT	TALDO1	0.999
TPI1	GAPDH	0.999
GPI	TPI1	0.999
GPI	PGM1	0.997
ALDOA	GAPDH	0.995
TPI1	GAPDHS	0.995
PFKM	PFKL	0.994
TALDO1	TKTL2	0.994
GPI	PFKM	0.993
HP	HBB	0.993
MMP9	TIMP2	0.992
H6PD	GPI	0.991
GPI	TALDO1	0.991
GPI	PFKP	0.991
GPI	PFKL	0.991
ALDOA	TPI1	0.99
GPI	TKT	0.99
PFKP	PFKM	0.989
TKTL1	TALDO1	0.989
PFKP	PFKL	0.987
GPI	PKM	0.987
GPI	GAPDH	0.986
TIMP2	MMP8	0.985
TKT	TPI1	0.984
CTSD	CTSH	0.983
TPI1	ALDOC	0.983
GPI	PKLR	0.983
ALDOA	ALDOC	0.981
CSTB	CTSH	0.98
CST3	CSTB	0.979
ALDOA	PKM	0.979
ALDOA	PFKP	0.979
TALDO1	TPI1	0.979
PFKP	ALDOC	0.978
ALDOA	PFKL	0.978
PFKL	ALDOC	0.977
ALDOA	PFKM	0.976
HP	ORM1	0.976
ALDOA	TALDO1	0.975
TKT	ALDOA	0.973
B2M	CST3	0.973
FBP1	TALDO1	0.973
PFKM	TALDO1	0.973
CST3	CTSD	0.972
GAPDH	ALDOC	0.972
GPI	GAPDHS	0.971
PFKM	ALDOC	0.971
TKT	GAPDH	0.97
PKM	GAPDH	0.969
PGAM1	TPI1	0.969
GPI	ALDOA	0.969
FBP1	GPI	0.969
TKT	PKM	0.967
ALDOA	GAPDHS	0.966
FBP2	TALDO1	0.966
H6PD	TPI1	0.966
ALDOC	GAPDHS	0.965
PKM	TPI1	0.964
CSTB	CTSD	0.964
IDH1	PGM1	0.964
MMP9	MMP8	0.964
PKM	PDHB	0.963
FBP1	ALDOA	0.962
B2M	CTSS	0.962
GPI	PGAM1	0.962
TKT	PFKM	0.962
FBP1	TKT	0.961
PFKP	TALDO1	0.961
GPI	TKTL1	0.961
TALDO1	PFKL	0.961
FBP2	ALDOC	0.961
GPI	FBP2	0.961
DAK	TPI1	0.96
CST3	CTSS	0.96
GPI	TKTL2	0.959
H6PD	TALDO1	0.959
CTSS	CTSD	0.959
H6PD	PGM1	0.959
DERA	TKTL2	0.958
FBP1	ALDOC	0.958
PGM1	TALDO1	0.957
ALDOA	PGM1	0.957
PKLR	PDHB	0.957
ALDOA	FBP2	0.957
H6PD	PKM	0.957
H6PD	GAPDH	0.957
MMP9	TNFAIP6	0.956
CST3	CTSH	0.955
ALDOA	TKTL2	0.954
H6PD	PKLR	0.954
HP	LTF	0.953
TKT	FBP2	0.952
TKT	ALDOC	0.952
PGM1	ALDOC	0.95
TALDO1	GAPDH	0.95
PKM	ALDOC	0.95
TALDO1	ALDOC	0.95
CST3	TIMP2	0.95
GPI	PGAM2	0.95
MMP8	LTF	0.949
TKT	PFKL	0.949
FBP2	PFKL	0.948
DERA	TALDO1	0.948
DERA	TKT	0.947
FBP1	PFKL	0.947
TKTL2	ALDOC	0.947
TKTL1	ALDOC	0.947
FBP2	PFKM	0.947
B2M	HP	0.946
IDH1	MMP9	0.946
FBP1	PFKM	0.945
PFKP	FBP2	0.945
TKTL1	PFKM	0.944
GPI	ALDOC	0.944
FBP1	PFKP	0.944
MMP9	CTSD	0.944
ALDOA	PKLR	0.944
PGM1	TPI1	0.943
ALDOA	LTA4H	0.943
PKLR	ALDOC	0.943
TKT	PFKP	0.943
TKTL2	PFKL	0.943
ALDOA	TKTL1	0.942
TKT	PGM1	0.941
ASAH1	CTSD	0.941
CST3	HP	0.941
PKLR	TPI1	0.941
B2M	CSTB	0.941
NIT2	PGM1	0.94
IDH1	LTA4H	0.94
PFKM	TPI1	0.94
IDH1	ALDOA	0.939
FBP2	TKTL1	0.939
FBP1	TKTL1	0.939
FBP1	TKTL2	0.939
FBP2	TKTL2	0.939
PGM1	LTA4H	0.939
PGM1	HP	0.939
CST3	MMP9	0.939
DERA	TKTL1	0.938
MMP9	LTF	0.938
MMP9	HP	0.937
PGM1	TKTL1	0.937
CTSS	CSTB	0.937
PGAM1	PGAM2	0.935
CHIT1	CNN2	0.935
MMP9	CTSS	0.935
PFKP	TKTL2	0.934
HBB	LTF	0.934
TKTL2	TPI1	0.934
PGM1	TKTL2	0.934
DERA	TPI1	0.933
HP	FTH1	0.933
PGAM1	TALDO1	0.933
TKTL1	PFKL	0.933
TALDO1	PKM	0.932
IDH1	ALDOC	0.932
TKTL1	TPI1	0.932
MMP9	CHIT1	0.93
FTH1	CTSD	0.93
KHK	ALDOC	0.93
TIMP2	CTSD	0.93
B2M	MMP9	0.929
PFKP	TKTL1	0.929
MMP9	LTA4H	0.929
B2M	HBB	0.929
PFKM	TKTL2	0.929
CTSS	CFP	0.929
DERA	ALDOA	0.928
FTH1	LTF	0.928
PFKP	PKM	0.928
FTH1	ALDOC	0.928
ALDOA	KHK	0.927
ORM1	LTF	0.927
PKM	TKTL2	0.927
MMP8	LTA4H	0.927
PKM	PFKL	0.927
PFKM	PKM	0.927
DERA	ALDOC	0.926
HP	MMP8	0.925
H6PD	TKT	0.925
B2M	LTF	0.925
TKT	PKLR	0.923
ALDOA	FTH1	0.923
CTSS	LTF	0.923
ALDOA	PGAM1	0.923
B2M	FTH1	0.922
TKTL1	PKM	0.922
METTL7A	ALDOC	0.922
CHIT1	CTSD	0.922
H6PD	GAPDHS	0.922
CTSS	CTSH	0.922
HP	CTSD	0.922
CTSS	FTH1	0.922
HBB	FTH1	0.921
GGH	CTSH	0.921
B2M	CTSH	0.921
B2M	CTSD	0.921
CTSS	MMP8	0.92
HP	CTSH	0.92
ALDOA	HBB	0.92
MMP9	CTSH	0.92
LTF	LTA4H	0.92
CSTB	LTF	0.92
B2M	TIMP2	0.919
CANT1	TIMP2	0.919
PFKP	TPI1	0.919
HP	CFP	0.919
ASAH1	CHIT1	0.919
PGM1	HBB	0.919
PFKL	TPI1	0.919
SPTAN1	CSTB	0.918
IDH1	HBB	0.918
MMP9	CFP	0.918
CTSS	TIMP2	0.918
PKLR	TKTL2	0.918
MMP8	CTSD	0.918
CST3	LTF	0.918
ORM1	MMP8	0.918
PGM1	ORM1	0.917
CST3	ORM1	0.917
PGM1	CTSD	0.916
B2M	IDH1	0.916
TKT	GAPDHS	0.916
TIMP2	TNFAIP6	0.916
ALDOA	CTSD	0.916
CTSS	HBB	0.916
CNN2	ALDOC	0.916
MMP9	ORM1	0.916
TALDO1	GAPDHS	0.915
PKLR	TALDO1	0.915
PGAM2	TPI1	0.915
CST3	FTH1	0.915
PGAM1	ALDOC	0.914
CST3	CHIT1	0.914
FTH1	CTSH	0.914
HBB	CTSD	0.914
ASAH1	CTSS	0.914
ALDOA	DAK	0.914
TNFAIP6	LTA4H	0.913
LTF	CTSH	0.913
CST3	HBB	0.913
SPTAN1	ALDOC	0.913
CTSS	TNFAIP6	0.913
B2M	ALDOA	0.913
TKTL1	GAPDH	0.913
CST3	MMP8	0.913
IDH1	FTH1	0.913
B2M	ORM1	0.913
TIMP2	CTSH	0.913
ASAH1	FTH1	0.912
MMP9	CSTB	0.912
HP	CSTB	0.912
ASAH1	HP	0.912
SPTAN1	CTSD	0.912
CSTB	TIMP2	0.912
ASAH1	MMP9	0.911
MMP9	FTH1	0.911
HBB	MMP8	0.911
MMP9	CNN2	0.911
ASAH1	CANT1	0.911
CTSS	LTA4H	0.911
FTH1	CNN2	0.911
B2M	CFP	0.91
DAK	ALDOC	0.91
HP	TIMP2	0.91
CANT1	ALDOC	0.91
ORM1	CFP	0.91
CTSD	LTF	0.91
B2M	NIT2	0.91
CHIT1	CTSH	0.91
MMP9	HBB	0.91
CHIT1	GGH	0.909
CFP	CTSH	0.909
CTSS	GGH	0.909
FTH1	LTA4H	0.909
ALDOA	HP	0.909
B2M	TNFAIP6	0.908
CST3	PGM1	0.908
ALDOA	CSTB	0.908
CHIT1	LTF	0.908
CTSD	ALDOC	0.908
ALDOA	MMP9	0.908
CSTB	MMP8	0.908
LTA4H	CTSH	0.908
HBB	CTSH	0.908
METTL7A	ALDOA	0.908
HBB	ORM1	0.908
CSTB	FTH1	0.908
TIMP2	LTF	0.908
ALDOA	CNN2	0.908
CTSD	LTA4H	0.908
LTF	ALDOC	0.907
NIT2	SPTAN1	0.907
B2M	LTA4H	0.907
PGM1	CANT1	0.907
CST3	ALDOC	0.907
CFP	CTSD	0.907
ALDOA	LTF	0.907
MMP9	PGM1	0.907
ALDOA	ORM1	0.907
MMP8	CTSH	0.907
TNFAIP6	MMP8	0.907
B2M	MMP8	0.907
B2M	ASAH1	0.907
CTSS	CHIT1	0.907
CSTB	LTA4H	0.907
TKTL1	PKLR	0.907
TNFAIP6	LTF	0.907
GGH	CTSD	0.907
ASAH1	SPTAN1	0.906
CSTB	ORM1	0.906
LTA4H	ALDOC	0.906
CNN2	MMP8	0.906
CTSS	ALDOC	0.906
FBP1	FBP2	0.906
HBB	CFP	0.906
ORM1	CTSD	0.906
IDH1	MMP8	0.906
ASAH1	CTSH	0.906
ALDOA	CANT1	0.906
ALDOA	TNFAIP6	0.906
CST3	ALDOA	0.906
PGM1	CNN2	0.906
ALDOA	CTSS	0.906
CHIT1	LTA4H	0.905
IDH1	CSTB	0.905
FTH1	TNFAIP6	0.905
CHIT1	HBB	0.905
FTH1	TIMP2	0.905
ALDOA	PDHB	0.905
CFP	TNFAIP6	0.905
ALDOA	TIMP2	0.905
IDH1	HP	0.905
TIMP2	LTA4H	0.905
ASAH1	LTA4H	0.905
FTH1	GGH	0.905
IDH1	ASAH1	0.905
CHIT1	ORM1	0.905
ALDOA	SPTAN1	0.905
CHIT1	MMP8	0.905
IDH1	CTSD	0.905
METTL7A	NIT2	0.904
CNN2	CFP	0.904
ASAH1	ORM1	0.904
ASAH1	CSTB	0.904
CFP	MMP8	0.904
CST3	CFP	0.904
CST3	ASAH1	0.904
PDHB	ALDOC	0.904
B2M	CHIT1	0.904
IDH1	NIT2	0.904
NIT2	FTH1	0.904
TKTL2	GAPDH	0.904
CTSS	HP	0.904
MMP8	ALDOC	0.904
PGM1	LTF	0.904
ALDOA	MMP8	0.904
NIT2	HP	0.904
SPTAN1	HP	0.904
MMP9	ALDOC	0.904
B2M	METTL7A	0.904
HBB	ALDOC	0.904
METTL7A	LTA4H	0.904
ORM1	TNFAIP6	0.904
IDH1	CTSH	0.903
ALDOA	CFP	0.903
TNFAIP6	CTSD	0.903
PGAM1	GAPDH	0.903
GGH	ALDOC	0.903
ASAH1	PGM1	0.903
CFP	ALDOC	0.903
SPTAN1	MMP9	0.903
HP	ALDOC	0.903
FTH1	ORM1	0.903
CHIT1	CFP	0.903
CANT1	CTSD	0.903
CHIT1	ALDOC	0.903
CSTB	GGH	0.903
NIT2	LTF	0.903
TIMP2	ALDOC	0.903
H6PD	ALDOC	0.903
CNN2	TIMP2	0.903
IDH1	GGH	0.903
B2M	ALDOC	0.903
CNN2	LTA4H	0.903
ALDOC	CTSH	0.903
ALDOA	CTSH	0.903
ORM1	LTA4H	0.903
METTL7A	HP	0.903
ASAH1	ALDOC	0.903
ALDOA	CHIT1	0.903
NIT2	LTA4H	0.903
METTL7A	HBB	0.903
ASAH1	LTF	0.903
CSTB	ALDOC	0.903
METTL7A	CTSS	0.902
B2M	CNN2	0.902
B2M	CANT1	0.902
IDH1	CNN2	0.902
CHIT1	TIMP2	0.902
CANT1	CTSH	0.902
NIT2	CTSD	0.902
HP	TNFAIP6	0.902
CTSS	CNN2	0.902
ORM1	ALDOC	0.902
NIT2	CANT1	0.902
CANT1	FTH1	0.902
CTSS	CANT1	0.902
SPTAN1	TIMP2	0.902
NIT2	ORM1	0.902
ALDOA	NIT2	0.902
IDH1	CANT1	0.902
CHIT1	HP	0.902
PGAM2	ALDOC	0.902
CNN2	CTSH	0.902
HBB	LTA4H	0.902
CHIT1	CSTB	0.902
TNFAIP6	ALDOC	0.902
METTL7A	PGM1	0.902
METTL7A	ORM1	0.902
HBB	TNFAIP6	0.902
ALDOA	ASAH1	0.902
ASAH1	TNFAIP6	0.902
NIT2	ALDOC	0.902
NIT2	CSTB	0.902
FTH1	MMP8	0.902
PKM	CANT1	0.902
ALDOA	PGAM2	0.902
HBB	TIMP2	0.902
B2M	GGH	0.902
FTH1	CFP	0.902
IDH1	TIMP2	0.902
HP	LTA4H	0.902
B2M	PGM1	0.902
METTL7A	CTSD	0.902
ASAH1	MMP8	0.902
PGM1	CHIT1	0.902
IDH1	CTSS	0.902
CNN2	TNFAIP6	0.902
ASAH1	GGH	0.902
METTL7A	LTF	0.901
ORM1	CTSH	0.901
NIT2	CTSH	0.901
GGH	LTF	0.901
SPTAN1	PGM1	0.901
IDH1	SPTAN1	0.901
METTL7A	CHIT1	0.901
CFP	LTF	0.901
TIMP2	CFP	0.901
CST3	TNFAIP6	0.901
METTL7A	ASAH1	0.901
NIT2	HBB	0.901
HP	GGH	0.901
ASAH1	TIMP2	0.901
SPTAN1	HBB	0.901
CST3	SPTAN1	0.901
METTL7A	FTH1	0.901
SPTAN1	CFP	0.901
IDH1	CST3	0.901
CHIT1	FTH1	0.901
CHIT1	TNFAIP6	0.901
SPTAN1	CHIT1	0.901
NIT2	CTSS	0.901
TNFAIP6	CTSH	0.901
MMP9	CANT1	0.901
MMP9	GGH	0.901
CTSS	ORM1	0.901
TIMP2	GGH	0.9
GGH	ORM1	0.9
CANT1	GGH	0.9
SPTAN1	CANT1	0.9
HP	CANT1	0.9
TIMP2	ORM1	0.9
ASAH1	HBB	0.9
NIT2	MMP9	0.9
METTL7A	GGH	0.9
CNN2	CTSD	0.9
SPTAN1	CTSH	0.9
PGM1	FTH1	0.9
METTL7A	SPTAN1	0.9
NIT2	TIMP2	0.9
CANT1	CSTB	0.9
CST3	CANT1	0.9
CANT1	ORM1	0.9
METTL7A	CST3	0.9
CST3	CNN2	0.9
NIT2	GGH	0.9
HBB	CANT1	0.9
SPTAN1	TNFAIP6	0.9
CANT1	MMP8	0.9
IDH1	LTF	0.9
IDH1	CHIT1	0.9
METTL7A	TNFAIP6	0.9
NIT2	MMP8	0.9
METTL7A	TIMP2	0.9
NIT2	CHIT1	0.9
SPTAN1	ORM1	0.9
CSTB	CFP	0.9
METTL7A	CNN2	0.9
IDH1	CFP	0.9
NIT2	TNFAIP6	0.9
SPTAN1	LTA4H	0.9
B2M	SPTAN1	0.9
SPTAN1	MMP8	0.9
CNN2	ORM1	0.9
PGM1	MMP8	0.9
GGH	LTA4H	0.9
HBB	CSTB	0.9
SPTAN1	GGH	0.9
HBB	CNN2	0.9
PGM1	GGH	0.9
PGM1	CTSH	0.9
CFP	LTA4H	0.9
CST3	NIT2	0.9
SPTAN1	CTSS	0.9
METTL7A	CTSH	0.9
METTL7A	CANT1	0.9
SPTAN1	CNN2	0.9
CSTB	CNN2	0.9
PGM1	TNFAIP6	0.9
H6PD	ALDOA	0.9
NIT2	CNN2	0.9
CANT1	CNN2	0.9
CSTB	TNFAIP6	0.9
CNN2	LTF	0.9
ALDOA	GGH	0.9
HP	CNN2	0.9
GGH	TNFAIP6	0.9
PGM1	CTSS	0.9
CST3	GGH	0.9
IDH1	ORM1	0.9
METTL7A	CSTB	0.9
METTL7A	MMP9	0.9
IDH1	TNFAIP6	0.9
CNN2	GGH	0.9
ASAH1	CNN2	0.9
CANT1	TNFAIP6	0.9
TALDO1	PGAM2	0.9
PGM1	CFP	0.9
HBB	GGH	0.9
CHIT1	CANT1	0.9
SPTAN1	LTF	0.9
GGH	MMP8	0.9
PGM1	TIMP2	0.9
NIT2	CFP	0.9
NIT2	ASAH1	0.9
PGM1	CSTB	0.9
PKLR	CANT1	0.9
CST3	LTA4H	0.9
METTL7A	MMP8	0.9
SPTAN1	FTH1	0.9
CANT1	LTF	0.9
METTL7A	CFP	0.9
METTL7A	IDH1	0.9
CANT1	LTA4H	0.9
GGH	CFP	0.9
CANT1	CFP	0.9
ASAH1	CFP	0.9

Gene Ontology Semantic Similarity

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#	462 (SERPINC1)	2266 (FGG)	2243 (FGA)	2147 (F2)	336 (APOA2)	3479 (IGF1)	335 (APOA1)	2157 (F8)	5340 (PLG)	197 (AHSG)	348 (APOE)	5345 (SERPINF2)	3481 (IGF2)	351 (APP)	3630 (INS)	7422 (VEGFA)	5265 (SERPINA1)	213 (ALB)	2335 (FN1)	3698 (ITIH2)	174 (AFP)	1191 (CLU)	1950 (EGF)	7018 (TF)	3569 (IL6)	116519 (APOA5)	7040 (TGFB1)	2 (A2M)	5054 (SERPINE1)	7450 (VWF)	1471 (CST3)	6696 (SPP1)	3484 (IGFBP1)	567 (B2M)	3082 (HGF)	2244 (FGB)	3827 (KNG1)	718 (C3)	1000 (CDH2)	5034 (P4HB)	1356 (CP)	720 (C4A)	652 (BMP4)	5004 (ORM1)	338 (APOB)	8074 (FGF23)	2217 (FCGRT)	7076 (TIMP1)	3263 (HPX)	10599 (SLCO1B1)
462 (SERPINC1)	1.00	0.69	0.69	0.58	0.54	0.66	0.57	1.00	0.63	0.50	0.51	0.94	0.58	0.84	0.76	0.61	0.94	0.56	0.69	0.90	1.00	0.72	0.48	0.63	0.67	0.47	0.67	0.81	0.97	0.74	0.87	0.68	0.60	0.72	0.49	0.70	0.72	0.61	0.75	0.48	0.49	0.36	0.65	1.00	0.55	0.16	0.51	0.87	1.00	0.11
2266 (FGG)	0.69	1.00	1.00	0.71	0.56	0.78	0.61	1.00	0.69	0.16	0.56	0.62	0.68	0.73	0.79	0.70	0.70	0.61	0.71	0.16	1.00	0.78	0.56	0.73	0.79	0.48	0.74	0.70	0.75	0.73	0.62	0.76	0.71	0.79	0.60	0.98	0.66	0.74	0.80	0.56	0.57	0.43	0.76	1.00	0.63	0.20	0.58	0.71	1.00	0.14
2243 (FGA)	0.69	1.00	1.00	0.71	0.56	0.78	0.61	1.00	0.69	0.16	0.56	0.62	0.68	0.73	0.79	0.70	0.70	0.61	0.71	0.16	1.00	0.78	0.56	0.73	0.79	0.48	0.74	0.70	0.75	0.73	0.62	0.76	0.71	0.79	0.60	0.98	0.66	0.74	0.80	0.56	0.57	0.43	0.76	1.00	0.63	0.20	0.58	0.71	1.00	0.14
2147 (F2)	0.58	0.71	0.71	1.00	0.51	0.68	0.56	1.00	0.82	0.12	0.51	0.53	0.64	0.66	0.70	0.67	0.61	0.56	0.67	0.13	1.00	0.67	0.60	0.62	0.74	0.44	0.68	0.65	0.66	0.67	0.54	0.63	0.64	0.67	0.55	0.72	0.59	0.85	0.69	0.50	0.47	0.61	0.66	1.00	0.55	0.16	0.58	0.61	1.00	0.11
336 (APOA2)	0.54	0.56	0.56	0.51	1.00	0.53	0.88	1.00	0.56	0.22	0.82	0.59	0.54	0.59	0.56	0.62	0.57	0.56	0.59	0.50	1.00	0.55	0.49	0.51	0.53	0.83	0.55	0.62	0.57	0.61	0.56	0.51	0.48	0.55	0.48	0.58	0.56	0.52	0.56	0.49	0.40	0.30	0.54	1.00	0.71	0.17	0.44	0.54	1.00	0.18
3479 (IGF1)	0.66	0.78	0.78	0.68	0.53	1.00	0.57	1.00	0.68	0.12	0.52	0.60	0.77	0.72	0.93	0.64	0.68	0.59	0.76	0.13	1.00	0.74	0.53	0.69	0.72	0.47	0.68	0.69	0.74	0.80	0.60	0.72	0.73	0.74	0.55	0.78	0.66	0.72	0.76	0.63	0.54	0.40	0.68	1.00	0.60	0.15	0.58	0.67	1.00	0.11
335 (APOA1)	0.57	0.61	0.61	0.56	0.88	0.57	1.00	1.00	0.61	0.17	0.81	0.56	0.57	0.64	0.62	0.61	0.61	0.60	0.65	0.33	1.00	0.59	0.52	0.55	0.57	0.81	0.60	0.65	0.60	0.64	0.64	0.56	0.53	0.60	0.52	0.62	0.58	0.57	0.60	0.50	0.44	0.33	0.58	1.00	0.72	0.17	0.47	0.57	1.00	0.15
2157 (F8)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.16	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.13	1.00	1.00	1.00	1.00	1.00	0.82	1.00	1.00	1.00	1.00	1.00	1.00	0.82	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.82	0.61	1.00	1.00	1.00	0.21	0.82	1.00	1.00	0.15
5340 (PLG)	0.63	0.69	0.69	0.82	0.56	0.68	0.61	1.00	1.00	0.12	0.55	0.60	0.63	0.70	0.70	0.65	0.65	0.61	0.72	0.13	1.00	0.70	0.56	0.65	0.68	0.50	0.71	0.68	0.67	0.72	0.60	0.65	0.58	0.67	0.58	0.72	0.62	0.84	0.69	0.57	0.56	0.61	0.67	1.00	0.61	0.17	0.55	0.65	1.00	0.11
197 (AHSG)	0.50	0.16	0.16	0.12	0.22	0.12	0.17	0.16	0.12	1.00	0.16	0.53	0.23	0.33	0.12	0.13	0.39	0.14	0.11	1.00	0.16	0.13	0.18	0.13	0.13	0.23	0.12	0.28	0.44	0.12	0.48	0.15	0.11	0.14	0.18	0.16	0.38	0.12	0.14	0.11	0.11	0.09	0.14	0.16	0.12	0.17	0.12	0.39	0.16	0.08
348 (APOE)	0.51	0.56	0.56	0.51	0.82	0.52	0.81	1.00	0.55	0.16	1.00	0.54	0.52	0.58	0.57	0.64	0.56	0.63	0.63	0.33	1.00	0.54	0.48	0.53	0.52	0.81	0.55	0.59	0.54	0.61	0.59	0.51	0.47	0.56	0.49	0.57	0.61	0.51	0.55	0.46	0.40	0.30	0.54	1.00	0.75	0.17	0.44	0.51	1.00	0.18
5345 (SERPINF2)	0.94	0.62	0.62	0.53	0.59	0.60	0.56	1.00	0.60	0.53	0.54	1.00	0.56	0.84	0.70	0.63	0.92	0.55	0.66	1.00	1.00	0.64	0.48	0.57	0.61	0.48	0.62	0.81	0.93	0.74	0.89	0.59	0.53	0.65	0.48	0.64	0.74	0.56	0.67	0.46	0.43	0.33	0.60	1.00	0.52	0.17	0.47	0.85	1.00	0.10
3481 (IGF2)	0.58	0.68	0.68	0.64	0.54	0.77	0.57	1.00	0.63	0.23	0.52	0.56	1.00	0.66	0.77	0.65	0.62	0.55	0.66	0.23	1.00	0.65	0.61	0.59	0.69	0.52	0.62	0.67	0.65	0.69	0.56	0.61	0.62	0.64	0.57	0.69	0.59	0.62	0.67	0.51	0.45	0.34	0.62	1.00	0.53	0.20	0.50	0.60	1.00	0.11
351 (APP)	0.84	0.73	0.73	0.66	0.59	0.72	0.64	1.00	0.70	0.33	0.58	0.84	0.66	1.00	0.78	0.69	0.86	0.70	0.73	0.90	1.00	0.73	0.56	0.68	0.73	0.54	0.73	0.80	0.87	0.74	0.81	0.69	0.64	0.75	0.57	0.73	0.74	0.69	0.73	0.61	0.53	0.39	0.70	1.00	0.62	0.16	0.54	0.79	1.00	0.11
3630 (INS)	0.76	0.79	0.79	0.70	0.56	0.93	0.62	1.00	0.70	0.12	0.57	0.70	0.77	0.78	1.00	0.68	0.80	0.64	0.79	0.13	1.00	0.77	0.56	0.72	0.74	0.49	0.71	0.74	0.81	0.83	0.72	0.75	0.71	0.82	0.58	0.79	0.68	0.74	0.79	0.60	0.57	0.43	0.71	1.00	0.63	0.15	0.59	0.76	1.00	0.11
7422 (VEGFA)	0.61	0.70	0.70	0.67	0.62	0.64	0.61	1.00	0.65	0.13	0.64	0.63	0.65	0.69	0.68	1.00	0.66	0.62	0.74	0.17	1.00	0.65	0.62	0.62	0.75	0.55	0.68	0.66	0.67	0.70	0.61	0.68	0.62	0.68	0.66	0.70	0.70	0.66	0.66	0.59	0.50	0.37	0.74	1.00	0.66	0.17	0.52	0.65	1.00	0.11
5265 (SERPINA1)	0.94	0.70	0.70	0.61	0.57	0.68	0.61	1.00	0.65	0.39	0.56	0.92	0.62	0.86	0.80	0.66	1.00	0.61	0.73	0.90	1.00	0.73	0.52	0.66	0.69	0.49	0.72	0.81	0.93	0.82	0.88	0.70	0.60	0.85	0.54	0.72	0.73	0.65	0.75	0.53	0.53	0.39	0.67	1.00	0.60	0.16	0.54	0.85	1.00	0.11
213 (ALB)	0.56	0.61	0.61	0.56	0.56	0.59	0.60	1.00	0.61	0.14	0.63	0.55	0.55	0.70	0.64	0.62	0.61	1.00	0.65	0.16	1.00	0.64	0.50	0.62	0.60	0.50	0.60	0.60	0.58	0.67	0.57	0.59	0.51	0.64	0.52	0.65	0.61	0.57	0.63	0.56	0.50	0.34	0.60	1.00	0.59	0.18	0.51	0.57	1.00	0.13
2335 (FN1)	0.69	0.71	0.71	0.67	0.59	0.76	0.65	1.00	0.72	0.11	0.63	0.66	0.66	0.73	0.79	0.74	0.73	0.65	1.00	0.13	1.00	0.73	0.57	0.67	0.71	0.58	0.72	0.72	0.73	0.85	0.67	0.68	0.62	0.73	0.58	0.74	0.73	0.69	0.71	0.62	0.57	0.39	0.68	1.00	0.72	0.14	0.56	0.70	1.00	0.10
3698 (ITIH2)	0.90	0.16	0.16	0.13	0.50	0.13	0.33	0.13	0.13	1.00	0.33	1.00	0.23	0.90	0.13	0.17	0.90	0.16	0.13	1.00	0.13	0.13	0.23	0.13	0.13	0.40	0.13	0.90	0.90	0.13	1.00	0.13	0.10	0.13	0.23	0.16	0.90	0.13	0.13	0.13	0.10	0.08	0.16	0.13	0.13	0.23	0.13	0.80	0.13	0.07
174 (AFP)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.16	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.13	1.00	1.00	1.00	1.00	1.00	0.82	1.00	1.00	1.00	1.00	1.00	1.00	0.82	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.82	0.61	1.00	1.00	1.00	0.21	0.82	1.00	1.00	0.15
1191 (CLU)	0.72	0.78	0.78	0.67	0.55	0.74	0.59	1.00	0.70	0.13	0.54	0.64	0.65	0.73	0.77	0.65	0.73	0.64	0.73	0.13	1.00	1.00	0.54	0.74	0.77	0.46	0.72	0.69	0.73	0.77	0.64	0.80	0.67	0.82	0.57	0.82	0.64	0.71	0.83	0.57	0.69	0.45	0.72	1.00	0.64	0.16	0.59	0.71	1.00	0.12
1950 (EGF)	0.48	0.56	0.56	0.60	0.49	0.53	0.52	1.00	0.56	0.18	0.48	0.48	0.61	0.56	0.56	0.62	0.52	0.50	0.57	0.23	1.00	0.54	1.00	0.49	0.58	0.45	0.55	0.59	0.53	0.58	0.49	0.49	0.49	0.53	0.81	0.58	0.49	0.51	0.56	0.43	0.38	0.29	0.54	1.00	0.47	0.59	0.50	0.50	1.00	0.10
7018 (TF)	0.63	0.73	0.73	0.62	0.51	0.69	0.55	1.00	0.65	0.13	0.53	0.57	0.59	0.68	0.72	0.62	0.66	0.62	0.67	0.13	1.00	0.74	0.49	1.00	0.71	0.43	0.67	0.66	0.68	0.71	0.57	0.71	0.66	0.75	0.50	0.74	0.68	0.66	0.78	0.50	0.51	0.38	0.67	1.00	0.57	0.15	0.54	0.64	1.00	0.11
3569 (IL6)	0.67	0.79	0.79	0.74	0.53	0.72	0.57	1.00	0.68	0.13	0.52	0.61	0.69	0.73	0.74	0.75	0.69	0.60	0.71	0.13	1.00	0.77	0.58	0.71	1.00	0.46	0.76	0.69	0.75	0.72	0.61	0.75	0.74	0.78	0.60	0.79	0.66	0.73	0.79	0.54	0.56	0.42	0.77	1.00	0.61	0.15	0.56	0.76	1.00	0.11
116519 (APOA5)	0.47	0.48	0.48	0.44	0.83	0.47	0.81	0.82	0.50	0.23	0.81	0.48	0.52	0.54	0.49	0.55	0.49	0.50	0.58	0.40	0.82	0.46	0.45	0.43	0.46	1.00	0.51	0.60	0.51	0.49	0.48	0.43	0.41	0.45	0.43	0.49	0.56	0.45	0.46	0.39	0.33	0.25	0.47	0.82	0.74	0.19	0.38	0.48	0.82	0.14
7040 (TGFB1)	0.67	0.74	0.74	0.68	0.55	0.68	0.60	1.00	0.71	0.12	0.55	0.62	0.62	0.73	0.71	0.68	0.72	0.60	0.72	0.13	1.00	0.72	0.55	0.67	0.76	0.51	1.00	0.71	0.73	0.74	0.62	0.69	0.68	0.76	0.57	0.75	0.66	0.70	0.73	0.56	0.53	0.40	0.83	1.00	0.63	0.15	0.61	0.72	1.00	0.11
2 (A2M)	0.81	0.70	0.70	0.65	0.62	0.69	0.65	1.00	0.68	0.28	0.59	0.81	0.67	0.80	0.74	0.66	0.81	0.60	0.72	0.90	1.00	0.69	0.59	0.66	0.69	0.60	0.71	1.00	0.84	0.72	0.78	0.66	0.64	0.68	0.59	0.71	0.72	0.67	0.70	0.56	0.51	0.38	0.68	1.00	0.62	0.17	0.52	0.78	1.00	0.11
5054 (SERPINE1)	0.97	0.75	0.75	0.66	0.57	0.74	0.60	1.00	0.67	0.44	0.54	0.93	0.65	0.87	0.81	0.67	0.93	0.58	0.73	0.90	1.00	0.73	0.53	0.68	0.75	0.51	0.73	0.84	1.00	0.75	0.86	0.70	0.67	0.74	0.54	0.76	0.77	0.70	0.76	0.52	0.52	0.39	0.71	1.00	0.59	0.17	0.53	0.89	1.00	0.11
7450 (VWF)	0.74	0.73	0.73	0.67	0.61	0.80	0.64	1.00	0.72	0.12	0.61	0.74	0.69	0.74	0.83	0.70	0.82	0.67	0.85	0.13	1.00	0.77	0.58	0.71	0.72	0.49	0.74	0.72	0.75	1.00	0.72	0.73	0.63	0.83	0.61	0.76	0.66	0.70	0.76	0.66	0.61	0.43	0.70	1.00	0.65	0.15	0.64	0.74	1.00	0.11
1471 (CST3)	0.87	0.62	0.62	0.54	0.56	0.60	0.64	1.00	0.60	0.48	0.59	0.89	0.56	0.81	0.72	0.61	0.88	0.57	0.67	1.00	1.00	0.64	0.49	0.57	0.61	0.48	0.62	0.78	0.86	0.72	1.00	0.59	0.53	0.67	0.49	0.64	0.75	0.56	0.66	0.47	0.44	0.33	0.60	1.00	0.53	0.17	0.48	0.82	1.00	0.11
6696 (SPP1)	0.68	0.76	0.76	0.63	0.51	0.72	0.56	1.00	0.65	0.15	0.51	0.59	0.61	0.69	0.75	0.68	0.70	0.59	0.68	0.13	1.00	0.80	0.49	0.71	0.75	0.43	0.69	0.66	0.70	0.73	0.59	1.00	0.67	0.82	0.51	0.77	0.59	0.68	0.84	0.51	0.57	0.42	0.70	1.00	0.59	0.17	0.58	0.68	1.00	0.13
3484 (IGFBP1)	0.60	0.71	0.71	0.64	0.48	0.73	0.53	0.82	0.58	0.11	0.47	0.53	0.62	0.64	0.71	0.62	0.60	0.51	0.62	0.10	0.82	0.67	0.49	0.66	0.74	0.41	0.68	0.64	0.67	0.63	0.53	0.67	1.00	0.68	0.50	0.70	0.59	0.68	0.69	0.49	0.50	0.37	0.67	0.82	0.55	0.13	0.49	0.63	0.82	0.10
567 (B2M)	0.72	0.79	0.79	0.67	0.55	0.74	0.60	1.00	0.67	0.14	0.56	0.65	0.64	0.75	0.82	0.68	0.85	0.64	0.73	0.13	1.00	0.82	0.53	0.75	0.78	0.45	0.76	0.68	0.74	0.83	0.67	0.82	0.68	1.00	0.56	0.79	0.65	0.71	0.85	0.55	0.61	0.45	0.72	1.00	0.64	0.16	0.59	0.72	1.00	0.12
3082 (HGF)	0.49	0.60	0.60	0.55	0.48	0.55	0.52	1.00	0.58	0.18	0.49	0.48	0.57	0.57	0.58	0.66	0.54	0.52	0.58	0.23	1.00	0.57	0.81	0.50	0.60	0.43	0.57	0.59	0.54	0.61	0.49	0.51	0.50	0.56	1.00	0.62	0.49	0.52	0.59	0.44	0.39	0.30	0.66	1.00	0.47	0.73	0.43	0.51	1.00	0.13
2244 (FGB)	0.70	0.98	0.98	0.72	0.58	0.78	0.62	1.00	0.72	0.16	0.57	0.64	0.69	0.73	0.79	0.70	0.72	0.65	0.74	0.16	1.00	0.82	0.58	0.74	0.79	0.49	0.75	0.71	0.76	0.76	0.64	0.77	0.70	0.79	0.62	1.00	0.68	0.75	0.80	0.58	0.66	0.44	0.76	1.00	0.65	0.19	0.59	0.72	1.00	0.14
3827 (KNG1)	0.72	0.66	0.66	0.59	0.56	0.66	0.58	1.00	0.62	0.38	0.61	0.74	0.59	0.74	0.68	0.70	0.73	0.61	0.73	0.90	1.00	0.64	0.49	0.68	0.66	0.56	0.66	0.72	0.77	0.66	0.75	0.59	0.59	0.65	0.49	0.68	1.00	0.61	0.67	0.47	0.44	0.33	0.64	1.00	0.67	0.16	0.48	0.72	1.00	0.11
718 (C3)	0.61	0.74	0.74	0.85	0.52	0.72	0.57	1.00	0.84	0.12	0.51	0.56	0.62	0.69	0.74	0.66	0.65	0.57	0.69	0.13	1.00	0.71	0.51	0.66	0.73	0.45	0.70	0.67	0.70	0.70	0.56	0.68	0.68	0.71	0.52	0.75	0.61	1.00	0.74	0.51	0.51	0.67	0.69	1.00	0.57	0.15	0.51	0.64	1.00	0.11
1000 (CDH2)	0.75	0.80	0.80	0.69	0.56	0.76	0.60	1.00	0.69	0.14	0.55	0.67	0.67	0.73	0.79	0.66	0.75	0.63	0.71	0.13	1.00	0.83	0.56	0.78	0.79	0.46	0.73	0.70	0.76	0.76	0.66	0.84	0.69	0.85	0.59	0.80	0.67	0.74	1.00	0.58	0.63	0.47	0.74	1.00	0.66	0.16	0.61	0.74	1.00	0.12
5034 (P4HB)	0.48	0.56	0.56	0.50	0.49	0.63	0.50	1.00	0.57	0.11	0.46	0.46	0.51	0.61	0.60	0.59	0.53	0.56	0.62	0.13	1.00	0.57	0.43	0.50	0.54	0.39	0.56	0.56	0.52	0.66	0.47	0.51	0.49	0.55	0.44	0.58	0.47	0.51	0.58	1.00	0.44	0.31	0.55	1.00	0.47	0.15	0.44	0.50	1.00	0.10
1356 (CP)	0.49	0.57	0.57	0.47	0.40	0.54	0.44	0.82	0.56	0.11	0.40	0.43	0.45	0.53	0.57	0.50	0.53	0.50	0.57	0.10	0.82	0.69	0.38	0.51	0.56	0.33	0.53	0.51	0.52	0.61	0.44	0.57	0.50	0.61	0.39	0.66	0.44	0.51	0.63	0.44	1.00	0.33	0.53	0.82	0.44	0.16	0.42	0.50	0.82	0.10
720 (C4A)	0.36	0.43	0.43	0.61	0.30	0.40	0.33	0.61	0.61	0.09	0.30	0.33	0.34	0.39	0.43	0.37	0.39	0.34	0.39	0.08	0.61	0.45	0.29	0.38	0.42	0.25	0.40	0.38	0.39	0.43	0.33	0.42	0.37	0.45	0.30	0.44	0.33	0.67	0.47	0.31	0.33	1.00	0.39	0.61	0.33	0.13	0.31	0.37	0.61	0.08
652 (BMP4)	0.65	0.76	0.76	0.66	0.54	0.68	0.58	1.00	0.67	0.14	0.54	0.60	0.62	0.70	0.71	0.74	0.67	0.60	0.68	0.16	1.00	0.72	0.54	0.67	0.77	0.47	0.83	0.68	0.71	0.70	0.60	0.70	0.67	0.72	0.66	0.76	0.64	0.69	0.74	0.55	0.53	0.39	1.00	1.00	0.60	0.18	0.54	0.71	1.00	0.13
5004 (ORM1)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.16	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.13	1.00	1.00	1.00	1.00	1.00	0.82	1.00	1.00	1.00	1.00	1.00	1.00	0.82	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.82	0.61	1.00	1.00	1.00	0.21	0.82	1.00	1.00	0.15
338 (APOB)	0.55	0.63	0.63	0.55	0.71	0.60	0.72	1.00	0.61	0.12	0.75	0.52	0.53	0.62	0.63	0.66	0.60	0.59	0.72	0.13	1.00	0.64	0.47	0.57	0.61	0.74	0.63	0.62	0.59	0.65	0.53	0.59	0.55	0.64	0.47	0.65	0.67	0.57	0.66	0.47	0.44	0.33	0.60	1.00	1.00	0.14	0.48	0.57	1.00	0.18
8074 (FGF23)	0.16	0.20	0.20	0.16	0.17	0.15	0.17	0.21	0.17	0.17	0.17	0.17	0.20	0.16	0.15	0.17	0.16	0.18	0.14	0.23	0.21	0.16	0.59	0.15	0.15	0.19	0.15	0.17	0.17	0.15	0.17	0.17	0.13	0.16	0.73	0.19	0.16	0.15	0.16	0.15	0.16	0.13	0.18	0.21	0.14	1.00	0.15	0.16	0.21	0.09
2217 (FCGRT)	0.51	0.58	0.58	0.58	0.44	0.58	0.47	0.82	0.55	0.12	0.44	0.47	0.50	0.54	0.59	0.52	0.54	0.51	0.56	0.13	0.82	0.59	0.50	0.54	0.56	0.38	0.61	0.52	0.53	0.64	0.48	0.58	0.49	0.59	0.43	0.59	0.48	0.51	0.61	0.44	0.42	0.31	0.54	0.82	0.48	0.15	1.00	0.52	0.82	0.11
7076 (TIMP1)	0.87	0.71	0.71	0.61	0.54	0.67	0.57	1.00	0.65	0.39	0.51	0.85	0.60	0.79	0.76	0.65	0.85	0.57	0.70	0.80	1.00	0.71	0.50	0.64	0.76	0.48	0.72	0.78	0.89	0.74	0.82	0.68	0.63	0.72	0.51	0.72	0.72	0.64	0.74	0.50	0.50	0.37	0.71	1.00	0.57	0.16	0.52	1.00	1.00	0.11
3263 (HPX)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.16	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.13	1.00	1.00	1.00	1.00	1.00	0.82	1.00	1.00	1.00	1.00	1.00	1.00	0.82	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.82	0.61	1.00	1.00	1.00	0.21	0.82	1.00	1.00	0.15
10599 (SLCO1B1)	0.11	0.14	0.14	0.11	0.18	0.11	0.15	0.15	0.11	0.08	0.18	0.10	0.11	0.11	0.11	0.11	0.11	0.13	0.10	0.07	0.15	0.12	0.10	0.11	0.11	0.14	0.11	0.11	0.11	0.11	0.11	0.13	0.10	0.12	0.13	0.14	0.11	0.11	0.12	0.10	0.10	0.08	0.13	0.15	0.18	0.09	0.11	0.11	0.15	1.00

Association with High Altitude

Protein Official symbol	Source Organism	Tissue of Expression	Level of hypoxia	Altitude	Duration of experiment	Level of expression	Fold change	Experiment details	geographical location	ethnicity of the patients	Control group	Control (Fold change)	Reference (PMID)
ALB	Human	Skeletal muscle	-	4559 m	9 day	upregulated	-4.81	2-DIGE	Southern Europe	Italians	1	Fasting control subjects at laboratory in Copenhagen with no caffeine intake	18937252
ALB	Rat	Lungs	-	7600 m	12 hours	upregulated	1.5	2-DE	northern Indo-Australian Plate	Sprague-Dawley	1	Male SD rats weighing 220g	26022216
ALB	Rat	Lungs	-	7600 m	24 hours	upregulated	1.2	2-DE	northern Indo-Australian Plate	Sprague-Dawley	1	Male SD rats weighing 220g	26022216
ALB	Rat	Plasma	-	7619 m	24 hours	upregulated	1.08	2-DE	Northern indo-australian plate	Male sprague-dawley	1	8 weeks old male SD rats kept at standard conditions	26882918
ALB	Rat	Lungs	-	7600 m	6 hours	upregulated	1.6	2-DE	northern Indo-Australian Plate	Sprague-Dawley	1	Male SD rats weighing 220g	26022216
ALB	Rat	Left brain cortices	300hPa	9144 m	1 hour	downregulated	0.75±0.1	TMT labeled LTQ orbitrap	Southwestern europe	Male wistar rats	1	Adult male Wistar rats weighing 350 g	28697276
ALB	Human	Serum	-	2400 m	0.5 hours	downregulated	0.474	2-DE	Western Europe	Germans	0.381	Healthy adults never had ear surgery or problems with pressure equalization	28858246

Association with TF

TF	TF Entrez	Gene	Gene Entrez	Type	PMID	Database
CHD2	1106	ALB	213	distal	22955619	TRANSFAC
HEY1	23462	ALB	213	distal	22955619	TRANSFAC
MAX	4149	ALB	213	distal	22955619	TRANSFAC
TAL1	6886	ALB	213	distal	22955619	TRANSFAC
YY1	7528	ALB	213	distal	22955619	TRANSFAC
CEBPB	1051	ALB	213	distal	22955619	TRANSFAC
GATA2	2624	ALB	213	distal	22955619	TRANSFAC
E2F6	1876	ALB	213	distal	22955619	TRANSFAC
EP300	2033	ALB	213	distal	22955619	TRANSFAC
TBP	6908	ALB	213	distal	22955619	TRANSFAC
MAFK	7975	ALB	213	distal	22955619	TRANSFAC
FOXA1	3169	ALB	213	proximal_filtered	22955619	TRANSFAC
CEBPA	1050	ALB	213	Repression	18031796	TRUSST
TEF	7008	ALB	213	Repression	20514445	TRUSST
HNF1A	6927	ALB	213	Repression	12485897	TRUSST

Association with miRNA

miRTarBase ID	miRNA	Species (miRNA)	Protein Official Symbol	Human Entrez ID	Species (Target Gene)	Experiments	Support Type	References (PMID)
MIRT006073	hsa-miR-492	Homo sapiens	ALB	213	Homo sapiens	Microarray//qRT-PCR	Functional MTI (Weak)	21319197

Gene Ontology

ID	GO ID	GO Term	GO Type
213	GO:0019836	hemolysis by symbiont of host erythrocytes	GOTERM_BP_DIRECT
213	GO:0005576	extracellular region	GOTERM_CC_DIRECT
213	GO:0005515	protein binding	GOTERM_MF_DIRECT
213	GO:0072562	blood microparticle	GOTERM_CC_DIRECT
213	GO:0009267	cellular response to starvation	GOTERM_BP_DIRECT
213	GO:0043066	negative regulation of apoptotic process	GOTERM_BP_DIRECT
213	GO:0016209	AMP binding	GOTERM_MF_DIRECT
213	GO:0098869	cellular oxidant detoxification	GOTERM_BP_DIRECT
213	GO:0019825	procollagen-proline dioxygenase activity	GOTERM_MF_DIRECT
213	GO:0051087	chaperone binding	GOTERM_MF_DIRECT
213	GO:0005783	endoplasmic reticulum	GOTERM_CC_DIRECT
213	GO:0031093	platelet alpha granule lumen	GOTERM_CC_DIRECT
213	GO:0043069	negative regulation of programmed cell death	GOTERM_BP_DIRECT
213	GO:0003677	DNA binding	GOTERM_MF_DIRECT
213	GO:0001895	retina homeostasis	GOTERM_BP_DIRECT
213	GO:0002576	platelet degranulation	GOTERM_BP_DIRECT
213	GO:0008144	drug binding	GOTERM_MF_DIRECT
213	GO:0015643	cholesterol binding	GOTERM_MF_DIRECT
213	GO:0030170	low-density lipoprotein particle binding	GOTERM_MF_DIRECT
213	GO:0043252	sodium-independent organic anion transport	GOTERM_BP_DIRECT
213	GO:0015721	bile acid and bile salt transport	GOTERM_BP_DIRECT
213	GO:0042802	identical protein binding	GOTERM_MF_DIRECT
213	GO:0005794	Golgi apparatus	GOTERM_CC_DIRECT
213	GO:0043234	protein complex	GOTERM_CC_DIRECT
213	GO:0005615	extracellular space	GOTERM_CC_DIRECT
213	GO:0005634	nucleus	GOTERM_CC_DIRECT
213	GO:0051659	maintenance of mitochondrion location	GOTERM_BP_DIRECT
213	GO:0070062	extracellular exosome	GOTERM_CC_DIRECT
213	GO:0006810	transport	GOTERM_BP_DIRECT
213	GO:0006898	receptor-mediated endocytosis	GOTERM_BP_DIRECT
213	GO:0042157	lipoprotein metabolic process	GOTERM_BP_DIRECT
213	GO:0005504	retinoid binding	GOTERM_MF_DIRECT
213	GO:0043209	myelin sheath	GOTERM_CC_DIRECT
213	GO:0005507	iron ion binding	GOTERM_MF_DIRECT

Pathways

Human Entrez ID	KEGG ID	KEGG Term

Association with Disease

Protein Official Symbol	Human Entrez ID	Disease Name	Disease Id	Disease Semantic Type	Semantic score	DSI	DPI	Disease Type
ALB	213	Toxic Epidermal Necrolysis	C0014518	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Nodular glomerulosclerosis	C0017667	Disease or Syndrome	0.32	0.412	0.828	disease
ALB	213	Heart Diseases	C0018799	Disease or Syndrome	0.3	0.412	0.828	group
ALB	213	Kidney Diseases	C0022658	Disease or Syndrome	0.4	0.412	0.828	group
ALB	213	Pain	C0030193	Sign or Symptom	0.3	0.412	0.828	phenotype
ALB	213	Brain Ischemia	C0007786	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Drug toxicity	C0013221	Injury or Poisoning	0.3	0.412	0.828	group
ALB	213	Kidney Failure, Chronic	C0022661	Disease or Syndrome	0.4	0.412	0.828	disease
ALB	213	Pancreatitis	C0030305	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Idiopathic Membranous Glomerulonephritis	C0086445	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Drug-Induced Liver Disease	C0860207	Disease or Syndrome	0.31	0.412	0.828	disease
ALB	213	Depressive Syndrome	C0086133	Mental or Behavioral Dysfunction	0.3	0.412	0.828	disease
ALB	213	Adenocarcinoma of lung (disorder)	C0152013	Neoplastic Process	0.3	0.412	0.828	disease
ALB	213	Endogenous depression	C0011573	Mental or Behavioral Dysfunction	0.3	0.412	0.828	disease
ALB	213	Malignant neoplasm of stomach	C0024623	Neoplastic Process	0.31	0.412	0.828	disease
ALB	213	Myopathy	C0026848	Disease or Syndrome	0.3	0.412	0.828	group
ALB	213	Serum Sickness	C0036830	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Nephritis, Tubulointerstitial	C0041349	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Adverse reaction to drug	C0041755	Pathologic Function	0.3	0.412	0.828	group
ALB	213	Encephalopathies	C0085584	Disease or Syndrome	0.31	0.412	0.828	group
ALB	213	Radiating pain	C0234254	Sign or Symptom	0.3	0.412	0.828	phenotype
ALB	213	Depression, Neurotic	C0282126	Mental or Behavioral Dysfunction	0.3	0.412	0.828	disease
ALB	213	Congestive heart failure	C0018802	Disease or Syndrome	0.31	0.412	0.828	disease
ALB	213	Left-Sided Heart Failure	C0023212	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Respiratory Distress Syndrome, Adult	C0035222	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Drug-Induced Stevens Johnson Syndrome	C1274933	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Chemically-Induced Liver Toxicity	C4279912	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Acute Kidney Insufficiency	C1565662	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Hereditary Diffuse Gastric Cancer	C1708349	Neoplastic Process	0.3	0.412	0.828	disease
ALB	213	Membranous glomerulonephritis	C0017665	Disease or Syndrome	0.36	0.412	0.828	disease
ALB	213	HIV Infections	C0019693	Disease or Syndrome	0.3	0.412	0.828	group
ALB	213	Liver Cirrhosis	C0023890	Disease or Syndrome	0.4	0.412	0.828	disease
ALB	213	Nephritis, Interstitial	C0027707	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Depressive disorder	C0011581	Mental or Behavioral Dysfunction	0.3	0.412	0.828	disease
ALB	213	Hemolytic-Uremic Syndrome	C0019061	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Hepatitis	C0019158	Disease or Syndrome	0.33	0.412	0.828	disease
ALB	213	Nephritis	C0027697	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Ache	C0234238	Sign or Symptom	0.3	0.412	0.828	phenotype
ALB	213	Thrombocytopenia	C0040034	Disease or Syndrome	0.3	0.412	0.828	phenotype
ALB	213	Unipolar Depression	C0041696	Mental or Behavioral Dysfunction	0.3	0.412	0.828	disease
ALB	213	Pain, Splitting	C0458257	Sign or Symptom	0.3	0.412	0.828	phenotype
ALB	213	Arthritis, Experimental	C0993582	Experimental Model of Disease	0.3	0.412	0.828	disease
ALB	213	Azoospermia	C0004509	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Diabetic Nephropathy	C0011881	Disease or Syndrome	0.4	0.412	0.828	disease
ALB	213	Liver Cirrhosis, Experimental	C0023893	Experimental Model of Disease	0.3	0.412	0.828	disease
ALB	213	Microangiopathy, Diabetic	C0025945	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Urticaria	C0042109	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Cardiovascular Diseases	C0007222	Disease or Syndrome	0.4	0.412	0.828	group
ALB	213	Echinococcosis	C0013502	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Glomerulonephritis, Membranoproliferative	C0017662	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	HIV Seropositivity	C0019699	Laboratory or Test Result	0.3	0.412	0.828	phenotype
ALB	213	Keloid	C0022548	Acquired Abnormality	0.3	0.412	0.828	phenotype
ALB	213	Aseptic Meningitis	C0025290	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Occupational Diseases	C0028797	Disease or Syndrome	0.3	0.412	0.828	group
ALB	213	Stevens-Johnson Syndrome	C0038325	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Heart Failure, Right-Sided	C0235527	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Aura	C0236018	Finding	0.3	0.412	0.828	phenotype
ALB	213	Brain Lacerations	C0272945	Injury or Poisoning	0.3	0.412	0.828	disease
ALB	213	Awakening Epilepsy	C0751111	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Allergic Reaction	C1527304	Pathologic Function	0.3	0.412	0.828	phenotype
ALB	213	Bright Disease	C1704377	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Cirrhosis	C1623038	Disease or Syndrome	0.37	0.412	0.828	disease
ALB	213	Heymann Nephritis	C1704378	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Mycoplasma-Induced Stevens-Johnson Syndrome	C3658301	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	HIV Coinfection	C4505456	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Angioedema	C0002994	Pathologic Function	0.3	0.412	0.828	phenotype
ALB	213	Heart failure	C0018801	Disease or Syndrome	0.31	0.412	0.828	disease
ALB	213	Nephrosis	C0027720	Disease or Syndrome	0.31	0.412	0.828	disease
ALB	213	Pancreatic Diseases	C0030286	Disease or Syndrome	0.3	0.412	0.828	group
ALB	213	Anuria	C0003460	Disease or Syndrome	0.3	0.412	0.828	phenotype
ALB	213	Delayed Hypersensitivity	C0020522	Pathologic Function	0.3	0.412	0.828	phenotype
ALB	213	Myocardial Reperfusion Injury	C0027055	Pathologic Function	0.3	0.412	0.828	phenotype
ALB	213	Respiratory Tract Diseases	C0035242	Disease or Syndrome	0.3	0.412	0.828	group
ALB	213	Fibrosis, Liver	C0239946	Disease or Syndrome	0.35	0.412	0.828	disease
ALB	213	Pain, Crushing	C0458259	Sign or Symptom	0.3	0.412	0.828	phenotype
ALB	213	Cerebral Ischemia	C0917798	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Hepatitis, Drug-Induced	C1262760	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Epilepsy, Cryptogenic	C0086237	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Liver Failure, Acute	C0162557	Disease or Syndrome	0.31	0.412	0.828	disease
ALB	213	Diabetic Angiopathies	C0011875	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Epilepsy	C0014544	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Glomerulonephritis	C0017658	Disease or Syndrome	0.33	0.412	0.828	disease
ALB	213	Uveitis	C0042164	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Brain Injuries, Focal	C0452047	Injury or Poisoning	0.3	0.412	0.828	group
ALB	213	Suffering, Physical	C0751408	Sign or Symptom	0.3	0.412	0.828	phenotype
ALB	213	Melancholia	C0025193	Mental or Behavioral Dysfunction	0.3	0.412	0.828	disease
ALB	213	Nephrotic Syndrome	C0027726	Disease or Syndrome	0.34	0.412	0.828	group
ALB	213	Poisoning	C0032343	Injury or Poisoning	0.3	0.412	0.828	group
ALB	213	Hypoalbuminemia	C0239981	Disease or Syndrome	0.45	0.412	0.828	disease
ALB	213	Arthritis, Collagen-Induced	C0971858	Experimental Model of Disease	0.3	0.412	0.828	disease
ALB	213	Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum	C3658302	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Drug-Induced Acute Liver Injury	C3658290	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Arthritis, Adjuvant-Induced	C0003865	Experimental Model of Disease	0.3	0.412	0.828	disease
ALB	213	Brain Diseases	C0006111	Disease or Syndrome	0.31	0.412	0.828	group
ALB	213	Fibrosis	C0016059	Pathologic Function	0.3	0.412	0.828	phenotype
ALB	213	Hypertensive disease	C0020538	Disease or Syndrome	0.4	0.412	0.828	group
ALB	213	Rhinitis, Allergic, Perennial	C0035457	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Hypersensitivity	C0020517	Pathologic Function	0.3	0.412	0.828	group
ALB	213	Hypotension	C0020649	Finding	0.4	0.412	0.828	phenotype
ALB	213	Membranoproliferative Glomerulonephritis, Type II	C0268743	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Brain Injuries	C0270611	Injury or Poisoning	0.3	0.412	0.828	group
ALB	213	Hepatitis, Toxic	C0019193	Injury or Poisoning	0.3	0.412	0.828	disease
ALB	213	Stomach Neoplasms	C0038356	Neoplastic Process	0.3	0.412	0.828	group
ALB	213	Injuries, Acute Brain	C0085742	Injury or Poisoning	0.3	0.412	0.828	group
ALB	213	Pain, Burning	C0234230	Sign or Symptom	0.3	0.412	0.828	phenotype
ALB	213	Pain, Migratory	C0751407	Sign or Symptom	0.3	0.412	0.828	phenotype
ALB	213	Acute Cerebrovascular Accidents	C0751956	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Kidney Failure, Acute	C0022660	Disease or Syndrome	0.32	0.412	0.828	disease
ALB	213	Proteinuria	C0033687	Finding	0.3	0.412	0.828	phenotype
ALB	213	Cerebrovascular accident	C0038454	Disease or Syndrome	0.32	0.412	0.828	group
ALB	213	Membranoproliferative Glomerulonephritis, Type I	C0268742	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Membranoproliferative Glomerulonephritis, Type III	C1720821	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Myocardial Failure	C1959583	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Heart Decompensation	C1961112	Pathologic Function	0.3	0.412	0.828	phenotype
ALB	213	Acute kidney injury	C2609414	Injury or Poisoning	0.3	0.412	0.828	disease
ALB	213	Chemical and Drug Induced Liver Injury	C4277682	Disease or Syndrome	0.3	0.412	0.828	disease
ALB	213	Hyperthyroxinemia, Familial Dysalbuminemic	C0342185	Disease or Syndrome	0.7	0.412	0.828	disease
ALB	213	Analbuminemia	C0878666	Finding	0.4	0.412	0.828	phenotype

Association with Drug

Protein Official Symbol	Human Entrez ID	drug_claim_primary_name	drug_name	drug_chembl_id	interaction_types
ALB	213	ANTISERUM	None	None	None
ALB	213	BISMUTH	BISMUTH SUBSALICYLATE	CHEMBL1120	binder
ALB	213	EBSELEN	EBSELEN	CHEMBL51085	binder
ALB	213	GADOBENATE DIMEGLUMINE	GADOBENATE DIMEGLUMINE	CHEMBL1200571	binder
ALB	213	IODIPAMIDE	IODIPAMIDE	CHEMBL1165268	binder
ALB	213	NAPROXEN	NAPROXEN	CHEMBL154	None
ALB	213	RALTITREXED	RALTITREXED	CHEMBL225071	None
ALB	213	SODIUM LAURYL SULFATE	SODIUM LAURYL SULFATE	CHEMBL23393	binder