ALTITUDEOMICSDB

Heat shock protein beta-1

AltitudeomicsDB

Protein Official symbol	HSPB1
Aliases	HSPB1 HSP27 HSP28
Chromosomal Location	7
Length	205
Uniprot ID	P04792
EC number	None
Protein family Information(Pfam)	PF00011;
PDB id	2N3J;3Q9P;3Q9Q;4MJH;6DV5;6GJH;
InterPro ID	IPR002068;IPR037876;IPR001436;IPR008978;
dbSNP	rs557327165 rs1393404971 rs375244209 rs770272088 rs121909113 rs29001571 rs558882005 rs28939680 rs863225022 rs28939681 rs121909112 rs28937568 rs374995963 rs28937569 rs774585320 rs772767500 rs764297134

Protein Protein Interaction

Download Tab separated file

AltitudeomicsDB

Protein 1	Protein 2	Combine Score
STIP1	HSP90AA1	0.999
NUP133	NUP107	0.999
HSPA8	DNAJB1	0.998
HSPA8	HSP90AA1	0.998
NUP205	NUP155	0.998
HSPA4	DNAJB1	0.998
HSPD1	HSPA9	0.998
NUP133	NUP155	0.997
NUP37	NUP43	0.997
NUP205	NUP107	0.996
NUP93	NUP155	0.996
NUP37	NUP107	0.996
NUP155	NUP107	0.995
NUP93	NUP205	0.995
NUP43	NUP107	0.995
NUP205	NUP133	0.995
NUP93	NUP107	0.994
HSP90AA1	DNAJB1	0.994
NUP43	NUP133	0.993
STIP1	DNAJB1	0.993
HSPA1A	DNAJB1	0.993
NUP153	NUP107	0.992
NUP88	NUP107	0.992
NUP62	NUP214	0.992
NUP88	NUP214	0.992
NUP62	NUP153	0.992
NUP153	NUP155	0.991
NUP93	NUP133	0.991
HSP90AA1	HSPA4	0.99
NUP37	NUP133	0.99
NUP62	NUP54	0.99
STIP1	AHSA1	0.99
NUP153	TPR	0.99
HSPA1A	HSP90AA1	0.99
NUP93	NUP54	0.989
NUP62	NUP107	0.989
NUP153	NUP93	0.989
NUP153	NUP133	0.989
NUP88	NUP153	0.989
NUP214	NUP107	0.989
NUP214	NUP155	0.988
NUP153	NUP205	0.988
NUP214	RANBP2	0.988
NUP54	NUP107	0.988
NUP62	NUP93	0.988
HSPA8	STIP1	0.988
HSPA5	DNAJB1	0.987
NUP214	NUP133	0.987
NUP88	NUP205	0.987
NUP62	NUP205	0.987
NUP62	NUP88	0.987
NUP62	NUP155	0.986
NUP214	NUP205	0.986
NUP214	NUP93	0.986
NUP88	NUP93	0.986
NUP214	NUP54	0.986
HSPD1	HSP90AA1	0.985
HSPA8	BAG1	0.985
NUP43	NUP93	0.985
DNAJC2	HSPA14	0.984
NUP153	NUP54	0.984
NUP62	NUP133	0.984
HSPA8	DNAJB6	0.984
NUP88	NUP54	0.984
NUP205	NUP54	0.984
BAG1	HSPA4	0.984
HSPA6	DNAJB1	0.984
NUP37	NUP93	0.983
NUP54	NUP155	0.983
TPR	NUP107	0.982
BAG3	HSPA4	0.982
NUP43	NUP155	0.982
NDC1	NUP93	0.982
RANBP2	NUP107	0.981
DNAJC19	HSPA9	0.981
NUP62	RANBP2	0.981
NUP37	NUP205	0.98
NUP88	NUP155	0.98
RAE1	NUP214	0.98
NUP43	NUP205	0.98
HSPA8	BAG3	0.98
HSPA4	HSPA9	0.979
HSPA9	DNAJB1	0.979
HSPA1B	DNAJB1	0.979
BAG1	BAG2	0.979
HSPA1L	DNAJB1	0.979
HSP90AA1	AHSA1	0.978
TPR	RANBP2	0.978
HSPA14	DNAJB6	0.978
STIP1	TCP1	0.978
NDC1	NUP155	0.978
NUP62	TPR	0.977
NUP54	NUP133	0.977
STIP1	HSPA4	0.977
HSPA4L	DNAJB1	0.976
HSPA2	DNAJB1	0.976
TPR	NUP214	0.976
HSP90AA1	STUB1	0.976
NUP62	NDC1	0.976
HSPA12A	HSPA4L	0.976
NUP93	RANBP2	0.975
NDC1	NUP205	0.975
HSPA12A	HSPA4	0.975
DNAJC2	HSPA4	0.975
HSPA12A	HSPA13	0.974
HSPA8	HSPH1	0.974
BAG2	HSPA4	0.974
RANBP2	NUP155	0.974
RANBP2	NUP133	0.974
HSPA12A	HSPA9	0.974
NUP88	RANBP2	0.974
TPR	NUP155	0.974
HSPA4	STUB1	0.973
HSPA4	ST13	0.973
NUP153	NUP214	0.973
HSPA8	ST13	0.972
TPR	NUP133	0.972
TPR	NUP93	0.972
TPR	NUP205	0.972
HSPA1A	DNAJB6	0.972
NUP37	NUP153	0.971
NUP205	RANBP2	0.971
NUP88	TPR	0.97
NUP43	NUP54	0.97
HSPA1A	STIP1	0.97
NUP153	NUP43	0.97
RAE1	NUP155	0.969
BAG5	HSPA4	0.969
RAE1	NUP54	0.969
NUP37	NUP155	0.969
HSPA14	DNAJB1	0.969
NUP153	RAE1	0.969
HSPH1	HSPA9	0.969
HSPA4	DNAJB6	0.969
RAE1	NUP93	0.968
RANBP2	NUP54	0.968
RAE1	NUP107	0.968
NUP62	RAE1	0.968
HSPA14	HSPA12A	0.968
HSPA8	BAG2	0.967
HSPA4	HSPA12B	0.966
HSPA9	HSPA4L	0.966
HSPA8	DNAJC7	0.966
NUP62	NUP43	0.966
NUP214	NUP43	0.966
HSPA1L	HSP90AA1	0.966
HSPA8	DNAJC2	0.965
HSPA2	HSP90AA1	0.965
NUP37	NUP214	0.965
NUP37	RANBP2	0.964
HSPA1B	HSP90AA1	0.964
NUP88	NUP133	0.964
NUP62	NUP37	0.964
NUP88	RAE1	0.963
RAE1	NUP205	0.962
NUP88	NUP37	0.962
HSPA1A	HSPA12B	0.962
HSPA1A	HSPA12A	0.962
HSPA6	DNAJB6	0.961
DNAJC7	HSPA4	0.961
HSPA9	DNAJB6	0.96
HSPA4	C11orf73	0.96
NDC1	NUP107	0.96
HSPA8	HSPA4	0.959
HSPA1A	BAG3	0.959
HSPA2	DNAJB6	0.959
HSPD1	HSPA5	0.958
NUP43	RANBP2	0.958
NUP88	NUP43	0.958
HSPA4	HSPBP1	0.957
HSPA12A	HSPH1	0.956
NUP37	NUP54	0.955
NUP153	NDC1	0.955
BAG1	HSPA1A	0.955
HSPA1B	DNAJB6	0.954
NUP37	NDC1	0.954
HSPA13	DNAJB1	0.954
SNCA	STUB1	0.954
HSPA9	HSPA12B	0.954
C11orf73	DNAJB1	0.954
HSPA8	BAG4	0.953
HSPA5	DNAJB6	0.953
RAE1	NUP133	0.953
RAE1	TPR	0.952
HSPA1L	DNAJB6	0.952
NUP153	RANBP2	0.952
HSPH1	HSPA12B	0.952
NDC1	RANBP2	0.951
NDC1	NUP133	0.95
HSPA14	HSPA12B	0.949
NUP88	NDC1	0.949
HSPA6	HSPA4	0.949
HSPA2	STIP1	0.949
HSPA1A	BAG2	0.948
HSPA8	BAG5	0.948
HSPA5	HSPH1	0.948
BAG5	HSPA5	0.947
HSPA2	BAG5	0.947
BAG3	HSPA6	0.946
HSPA5	HSPA4	0.946
TPR	NUP54	0.946
SNCA	HSPA4	0.945
DNAJC2	HSPA9	0.945
HSPA12A	HSPA5	0.945
NUP37	TPR	0.945
BAG1	HSPBP1	0.945
HSPA1L	BAG4	0.945
HSPA1B	BAG3	0.945
HSPA1L	STIP1	0.944
HSPA4L	HSPA12B	0.944
NUP62	HSPA4	0.944
HSPA4	BAG4	0.943
HSPA13	HSPA12B	0.943
HSPA5	HSPA4L	0.943
HSPA5	HSPA12B	0.943
HSPA4L	DNAJB6	0.943
HSPA1B	STIP1	0.943
HSP90AA1	HSPA5	0.943
HSPA9	ST13	0.942
DNAJC2	HSPA4L	0.942
NDC1	NUP214	0.942
HSPA13	DNAJB6	0.942
HSPA14	HSPA4	0.941
HSPD1	DNAJC19	0.941
TPR	NUP43	0.941
HSPA1A	ST13	0.941
NDC1	NUP43	0.941
HSPA6	HSPA12B	0.941
HSPA14	HSPH1	0.94
DNAJC2	HSPA5	0.94
HSPA12A	HSPA6	0.939
BAG3	HSPA5	0.939
RAE1	RANBP2	0.939
DNAJC2	HSPA1A	0.939
DNAJC7	HSPA4L	0.938
NDC1	NUP54	0.938
HSPA14	HSPA4L	0.938
HSPA2	HSPA4	0.938
HSPA1A	HSPA4	0.938
HSPA4	HSPA13	0.938
HSPA4L	HSPA13	0.937
HSPA1L	HSPA12A	0.937
HSPA6	HSPA4L	0.937
HSPA1A	BAG5	0.936
HSPA8	HSPA4L	0.936
HSPA8	HSPA12A	0.936
HSPA1L	HSPA4	0.936
HSPA1A	HSPH1	0.936
DNAJC7	HSPA1A	0.935
HSPA1L	HSPA4L	0.935
HSPA1B	HSPA4	0.935
DNAJC2	HSPA1B	0.934
HSPA2	DNAJC2	0.934
DNAJC2	HSPA1L	0.934
HSPH1	HSPA6	0.934
BAG2	HSPBP1	0.934
HSPA1A	HSPA4L	0.934
HSPA1L	HSPH1	0.933
HSPA1L	BAG3	0.933
HSPH1	HSPA13	0.933
HSPA2	HSPA4L	0.933
HSPA4	RANBP2	0.932
HSPA14	HSPA9	0.932
HSPA1L	BAG5	0.932
TCP1	HSPA4	0.931
HSPA1B	HSPA4L	0.931
HSPA2	HSPH1	0.931
RAE1	NUP43	0.931
DNAJC2	HSPA6	0.931
DNAJC2	HSPA12A	0.931
BAG3	HSPA9	0.931
DNAJC7	HSPA13	0.931
HSPA1B	ST13	0.931
BAG1	HSPA1B	0.931
HSPA8	HSPA9	0.931
DNAJC2	HSPA13	0.931
DNAJC2	HSPA12B	0.931
HSPA2	BAG2	0.93
HSPA1B	HSPH1	0.93
HSPA5	ST13	0.93
HSPD1	HSPA4	0.93
HSPA2	BAG3	0.93
NUP93	C11orf73	0.929
HSPA1B	BAG2	0.929
HSPA12A	DNAJB1	0.929
HSPA12B	DNAJB1	0.929
HSPA5	HSPA9	0.929
HSPA2	HSPA12A	0.929
BAG1	HSPA9	0.928
BAG1	HSPA5	0.928
BAG2	HSPA9	0.928
HSPA5	BAG4	0.928
HSPA8	C11orf73	0.927
HSPH1	HSPBP1	0.927
C11orf73	NUP155	0.927
HSPA6	HSPA9	0.927
HSP90AA1	HSPH1	0.927
HSPA14	HSPA13	0.926
DNAJC7	HSPA9	0.926
NUP37	RAE1	0.926
HSPA4	NUP155	0.925
HSPA8	HSPA6	0.925
HSPA8	HSPA5	0.924
HSPA9	RANBP2	0.924
HSPA9	HSPA13	0.924
HSPA12B	ST13	0.924
HSPA1L	BAG2	0.924
DNAJB6	HSPA12B	0.923
TPR	HSPA4	0.923
HSPA8	RANBP2	0.923
DNAJC7	HSPA5	0.923
HSPA4L	C11orf73	0.923
HSPA5	HSPA13	0.922
HSPA8	HSPA12B	0.922
NUP37	C11orf73	0.922
HSPA1A	HSPA5	0.922
HSPA1L	HSPA5	0.922
HSPA1L	HSPA12B	0.922
HSPA2	HSPA5	0.922
HSPA1B	HSPA5	0.921
HSPA14	BAG3	0.921
BAG1	HSPA2	0.921
BAG1	HSPA14	0.921
BAG2	HSPA5	0.92
C11orf73	NUP107	0.92
HSPA1L	ST13	0.92
HSPA4	NUP54	0.92
HSPA14	ST13	0.92
DNAJC7	HSPA1L	0.92
HSPA6	ST13	0.92
NUP153	C11orf73	0.92
HSPA14	HSPA5	0.92
DNAJC7	HSPA6	0.919
HSPH1	HSPA4	0.919
DNAJC7	HSPA14	0.919
HSPA1A	BAG4	0.918
HSPA14	NUP214	0.918
BAG3	HSPA4L	0.918
BAG1	HSPA6	0.918
HSPA9	BAG4	0.918
NUP37	HSPA14	0.918
C11orf73	NUP54	0.918
HSPA2	ST13	0.918
DNAJC7	HSPA12A	0.918
HSPA12A	BAG4	0.918
HSPA1B	BAG5	0.918
NUP37	HSPA8	0.918
HSPA14	NUP107	0.917
HSPA13	ST13	0.917
HSPA12A	ST13	0.917
BAG5	HSPA4L	0.917
HSPA14	HSPA6	0.917
HSPA1A	HSPA9	0.917
HSPA14	NUP155	0.917
HSPA14	NDC1	0.917
HSPA8	HSPA14	0.916
HSPA1B	HSPA9	0.916
NDC1	TPR	0.916
HSPA4	NUP107	0.916
HSPA2	HSPA9	0.916
HSPA12A	DNAJB6	0.916
HSPA4L	ST13	0.916
HSPA6	C11orf73	0.916
HSPA1L	HSPA9	0.916
BAG1	HSPA1L	0.916
NUP37	HSPA4	0.916
HSPA8	NUP214	0.916
RAE1	C11orf73	0.915
BAG4	HSPA12B	0.915
NUP153	HSPA8	0.915
BAG5	HSPA13	0.915
NUP88	HSPA4	0.915
HSPA5	RANBP2	0.915
BAG4	HSPA13	0.915
BAG2	HSPA4L	0.915
HSPA13	RANBP2	0.914
NUP205	C11orf73	0.914
HSPA5	HSPA6	0.914
HSPA8	RAE1	0.914
BAG5	HSPA9	0.914
HSPA4L	RANBP2	0.913
NUP214	HSPA4	0.913
HSPA14	HSPA1L	0.913
HSPA14	BAG5	0.913
HSPA8	NUP155	0.912
HSPA2	HSPA14	0.912
NUP37	HSPA4L	0.912
DNAJC7	HSPA1B	0.912
HSPA1B	BAG4	0.912
RAE1	HSPA4	0.912
HSPA4	AHSA1	0.912
HSPA14	HSPA1A	0.912
DNAJC7	HSPA12B	0.912
BAG2	HSPA13	0.912
HSPA14	TPR	0.912
HSPA14	NUP133	0.912
DNAJC7	HSPA2	0.912
RANBP2	C11orf73	0.912
NUP88	C11orf73	0.912
NUP62	HSPA8	0.912
BAG2	HSPA12B	0.911
HSPA1A	HSPA1B	0.911
HSPA8	HSPA13	0.911
NUP88	HSPA14	0.911
NUP62	HSPA9	0.911
HSPA2	C11orf73	0.911
DNAJC19	HSPA4	0.911
HSPA6	RANBP2	0.91
HSPA1L	HSPA13	0.91
NUP153	HSPA14	0.91
HSPA1A	C11orf73	0.91
HSPA14	RANBP2	0.91
NUP153	HSPA4	0.91
HSPA1L	C11orf73	0.91
HSPA14	BAG4	0.91
HSPA1B	C11orf73	0.91
NUP43	HSPA4	0.91
RAE1	HSPA14	0.91
HSPA6	HSPA13	0.909
HSPA1A	RANBP2	0.909
NUP88	HSPA8	0.909
HSPA12A	C11orf73	0.909
HSPA12B	NUP155	0.909
HSPA1A	HSPA6	0.909
NUP93	HSPA4	0.909
HSPA12A	RANBP2	0.909
C11orf73	NUP133	0.909
RAE1	NDC1	0.909
HSPA2	RANBP2	0.909
HSPA8	NUP54	0.909
RANBP2	HSPA12B	0.909
HSPA14	C11orf73	0.909
HSPA12A	NUP155	0.909
HSPA1L	NUP155	0.909
HSPA6	NUP155	0.909
HSPA1B	NUP155	0.909
HSPA13	C11orf73	0.909
BAG3	HSPA13	0.909
HSPA12A	BAG3	0.909
C11orf73	DNAJB6	0.909
HSPA14	HSPA1B	0.909
HSPA1A	NUP155	0.909
HSPA1B	RANBP2	0.909
HSPA2	NUP155	0.909
C11orf73	HSPA12B	0.909
HSPA1L	RANBP2	0.909
NUP62	HSPA14	0.909
HSPA13	NUP155	0.909
NUP43	C11orf73	0.908
HSPA14	NUP43	0.908
BAG1	HSPA4L	0.908
HSPA14	BAG2	0.908
HSPA8	NUP43	0.908
HSPH1	HSPA4L	0.908
NUP62	HSPA5	0.908
BAG2	HSPA6	0.908
HSPA1A	HSPA13	0.908
DNAJC2	C11orf73	0.908
HSPA9	C11orf73	0.908
HSPA9	NUP54	0.908
HSPA6	NUP54	0.908
NUP43	HSPA6	0.908
HSPA4	HSPA4L	0.907
HSPA4	NUP205	0.907
HSPA4L	NUP155	0.907
HSPA14	NUP54	0.907
HSPA14	NUP205	0.907
NUP37	HSPA6	0.907
HSPA9	NUP107	0.907
NUP37	HSPA9	0.907
NDC1	HSPA4	0.907
BAG5	HSPA6	0.907
HSPA4	NUP133	0.907
HSPA8	TPR	0.907
HSPD1	TCP1	0.907
NUP43	HSPA9	0.906
HSPA1L	HSPA6	0.906
HSPA6	BAG4	0.906
HSPA2	HSPA13	0.906
HSPA1B	HSPA6	0.906
HSPA9	NUP133	0.906
HSPA1B	HSPA13	0.906
HSPA12A	HSPA12B	0.906
HSPA8	NUP93	0.906
BAG3	HSPA12B	0.906
HSPA9	NUP205	0.906
HSPA1L	NUP214	0.905
NUP88	HSPA9	0.905
HSPA1A	NUP214	0.905
HSPA2	BAG4	0.905
HSPA1B	NUP214	0.905
RAE1	HSPA9	0.905
TPR	HSPA6	0.905
NDC1	HSPA9	0.905
HSPA4L	BAG4	0.905
RAE1	HSPA6	0.905
HSPA12A	BAG5	0.905
BAG5	HSPA12B	0.905
HSPA8	NDC1	0.905
HSPA5	C11orf73	0.905
HSPA1L	HSPA1A	0.905
NUP62	C11orf73	0.905
HSPA1A	NUP107	0.904
HSPA2	HSPA1L	0.904
RAE1	HSPA1A	0.904
HSPA8	HSPA1A	0.904
DNAJC7	C11orf73	0.904
HSPA1B	NUP107	0.904
NUP62	HSPA4L	0.904
HSPA1L	NUP107	0.904
HSPA8	NUP205	0.904
RAE1	HSPA1B	0.904
NDC1	C11orf73	0.904
NUP93	HSPA9	0.904
HSPA13	NUP54	0.904
HSPA8	NUP107	0.904
NUP37	HSPA13	0.904
RAE1	HSPA4L	0.904
NUP214	HSPA6	0.904
RAE1	HSPA1L	0.904
NUP88	HSPA1B	0.903
TPR	HSPA9	0.903
NUP88	HSPA1A	0.903
NUP88	HSPA2	0.903
NUP88	HSPA4L	0.903
NUP153	HSPA9	0.903
HSPA12A	NUP107	0.903
HSPA5	NUP155	0.903
NUP43	HSPA4L	0.903
HSPA1L	NUP93	0.903
HSPA5	NUP205	0.903
RAE1	HSPA2	0.903
HSPA13	NUP107	0.903
HSPA1B	NUP93	0.903
HSPA8	HSPA1L	0.903
HSPA8	NUP133	0.903
HSPA2	NUP107	0.903
BAG1	HSPA12B	0.903
HSPA12B	NUP107	0.903
NUP214	HSPA13	0.903
HSPA2	HSPA12B	0.903
HSPA9	NUP155	0.903
NUP93	HSPA6	0.903
HSPA2	NUP93	0.903
HSPA8	HSPA1B	0.903
HSPA12A	NUP214	0.903
NUP214	HSPA12B	0.903
HSPA6	NUP107	0.903
HSPA1A	NUP93	0.903
NUP88	HSPA1L	0.903
HSPA2	NUP214	0.903
NDC1	HSPA12B	0.902
NUP214	HSPA4L	0.902
NDC1	HSPA5	0.902
NUP153	HSPA1B	0.902
HSPA14	NUP93	0.902
HSPA2	NDC1	0.902
NUP37	HSPA1L	0.902
TPR	HSPA5	0.902
BAG1	HSPA12A	0.902
BAG1	HSPA13	0.902
RAE1	HSPA13	0.902
TPR	HSPA13	0.902
HSPA4L	NUP107	0.902
HSPA1L	NDC1	0.902
HSPA4L	NUP133	0.902
NDC1	HSPA4L	0.902
NUP37	HSPA1B	0.902
HSPA1B	NDC1	0.902
HSPA5	NUP54	0.902
NUP214	HSPA5	0.902
NUP88	HSPA5	0.902
HSPA2	HSPA6	0.902
HSPA1B	HSPA12A	0.902
HSPA5	NUP107	0.902
NUP88	HSPA6	0.902
NDC1	HSPA13	0.902
RAE1	HSPA12B	0.902
NUP153	HSPA4L	0.902
HSPA1A	NDC1	0.902
HSPD1	ST13	0.902
NDC1	HSPA12A	0.902
NUP37	HSPA1A	0.902
NDC1	HSPA6	0.902
RAE1	HSPA12A	0.902
NUP153	HSPA6	0.902
TPR	HSPA4L	0.902
NUP153	HSPA1A	0.902
RAE1	HSPA5	0.902
NUP214	HSPA9	0.902
TPR	C11orf73	0.902
NUP153	HSPA1L	0.902
NUP62	HSPA13	0.901
NUP88	HSPA12A	0.901
HSPA8	HSPA2	0.901
NUP62	HSPA12A	0.901
NUP62	HSPA1L	0.901
HSPA1A	TPR	0.901
HSPA6	NUP133	0.901
NUP62	HSPA12B	0.901
NUP153	HSPA13	0.901
HSPA1L	HSPA1B	0.901
NUP153	HSPA2	0.901
HSPA5	NUP93	0.901
NUP93	HSPA4L	0.901
HSPA6	NUP205	0.901
NUP153	HSPA12A	0.901
NUP62	HSPA1B	0.901
NUP62	HSPA6	0.901
NUP214	C11orf73	0.901
HSPA2	HSPA1A	0.901
NUP153	HSPA12B	0.901
NUP88	HSPA13	0.901
HSPA4L	NUP205	0.901
NUP62	HSPA1A	0.901
NUP88	HSPA12B	0.901
HSPA2	HSPA1B	0.901
NUP62	HSPA2	0.901
NUP37	HSPA2	0.901
HSPA12A	NUP43	0.9
NUP93	HSPA13	0.9
HSPA1A	NUP133	0.9
HSPA1B	NUP133	0.9
HSPA1B	NUP43	0.9
NUP93	HSPA12B	0.9
HSPA1A	NUP54	0.9
HSPA1A	NUP43	0.9
NUP43	HSPA12B	0.9
NUP43	HSPA5	0.9
HSPA1L	NUP43	0.9
HSPA5	NUP133	0.9
HSPA2	TPR	0.9
HSPA2	NUP54	0.9
NUP37	HSPA5	0.9
NUP133	HSPA12B	0.9
HSPA1B	TPR	0.9
NUP37	HSPA12A	0.9
HSPA12A	NUP205	0.9
TPR	HSPA12B	0.9
NUP153	HSPA5	0.9
HSPA2	NUP133	0.9
HSPA4L	NUP54	0.9
HSPA1A	NUP205	0.9
HSPA12A	NUP133	0.9
HSPA1B	NUP205	0.9
NUP54	HSPA12B	0.9
HSPA12A	NUP93	0.9
NUP205	HSPA13	0.9
HSPA13	NUP133	0.9
HSPA2	NUP205	0.9
HSPA2	NUP43	0.9
HSPA1L	NUP205	0.9
HSPA12A	TPR	0.9
HSPA1B	NUP54	0.9
BAG2	HSPA12A	0.9
NUP205	HSPA12B	0.9
NUP37	HSPA12B	0.9
HSPA12A	NUP54	0.9
HSPA1B	HSPA12B	0.9
HSPA1L	TPR	0.9
HSPA1L	NUP54	0.9
HSPA1L	NUP133	0.9
NUP43	HSPA13	0.9

Gene Ontology Semantic Similarity

Download Tab separated file

#	311 (ANXA11)	7316 (UBC)	3312 (HSPA8)	314 (AOC2)	9261 (MAPKAPK2)	7867 (MAPKAPK3)	207 (AKT1)	1616 (DAXX)	3315 (HSPB1)	8550 (MAPKAPK5)	7157 (TP53)	54205 (CYCS)	988 (CDC5L)	3303 (HSPA1A)	355 (FAS)	2099 (ESR1)	5600 (MAPK11)	6233 (RPS27A)	5596 (MAPK4)	26986 (PABPC1)	5597 (MAPK6)	58 (ACTA1)	3308 (HSPA4)	1432 (MAPK14)
311 (ANXA11)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00
7316 (UBC)	0.79	1.00	1.00	0.69	0.77	1.00	0.47	0.48	0.48	0.62	0.75	0.52	0.61	0.60	0.70	0.66	0.62	0.53	0.55	0.83	0.57	0.83	0.55	0.56	0.66	0.57
3312 (HSPA8)	0.78	1.00	0.69	1.00	0.63	1.00	0.51	0.51	0.59	0.64	0.66	0.53	0.66	0.58	0.63	0.90	0.59	0.55	0.54	0.65	0.56	0.69	0.54	0.67	0.68	0.58
314 (AOC2)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00
9261 (MAPKAPK2)	0.47	1.00	0.47	0.51	0.50	1.00	1.00	0.92	0.73	0.57	0.51	0.91	0.49	0.41	0.41	0.53	0.64	0.48	0.85	0.44	0.81	0.43	0.85	0.42	0.42	0.79
7867 (MAPKAPK3)	0.48	1.00	0.48	0.51	0.51	1.00	0.92	1.00	0.72	0.56	0.52	0.99	0.49	0.41	0.41	0.53	0.56	0.45	0.88	0.44	0.83	0.43	0.88	0.42	0.43	0.85
207 (AKT1)	0.55	1.00	0.48	0.59	0.48	1.00	0.73	0.72	1.00	0.55	0.55	0.73	0.56	0.43	0.42	0.59	0.52	0.53	0.70	0.44	0.70	0.44	0.70	0.57	0.56	0.72
1616 (DAXX)	0.57	1.00	0.62	0.64	0.64	1.00	0.57	0.56	0.55	1.00	0.68	0.59	0.64	0.56	0.57	0.69	0.67	0.61	0.59	0.59	0.64	0.56	0.59	0.56	0.59	0.65
3315 (HSPB1)	0.73	1.00	0.75	0.66	0.68	1.00	0.51	0.52	0.55	0.68	1.00	0.54	0.63	0.59	0.66	0.66	0.67	0.60	0.56	0.71	0.67	0.74	0.56	0.57	0.62	0.59
8550 (MAPKAPK5)	0.50	1.00	0.52	0.53	0.55	1.00	0.91	0.99	0.73	0.59	0.54	1.00	0.51	0.44	0.43	0.54	0.57	0.47	0.87	0.47	0.83	0.46	0.87	0.45	0.47	0.84
7157 (TP53)	0.64	1.00	0.61	0.66	0.54	1.00	0.49	0.49	0.56	0.64	0.63	0.51	1.00	0.53	0.71	0.71	0.56	0.74	0.50	0.57	0.54	0.61	0.50	0.57	0.56	0.57
54205 (CYCS)	0.57	1.00	0.60	0.58	0.60	1.00	0.41	0.41	0.43	0.56	0.59	0.44	0.53	1.00	0.50	0.58	0.55	0.48	0.43	0.54	0.47	0.54	0.43	0.47	0.50	0.48
988 (CDC5L)	0.70	1.00	0.70	0.63	0.52	1.00	0.41	0.41	0.42	0.57	0.66	0.43	0.71	0.50	1.00	0.64	0.52	0.62	0.42	0.66	0.45	0.71	0.42	0.45	0.46	0.46
3303 (HSPA1A)	0.74	1.00	0.66	0.90	0.63	1.00	0.53	0.53	0.59	0.69	0.66	0.54	0.71	0.58	0.64	1.00	0.59	0.56	0.55	0.63	0.56	0.66	0.55	0.65	0.66	0.59
355 (FAS)	0.56	1.00	0.62	0.59	0.66	1.00	0.64	0.56	0.52	0.67	0.67	0.57	0.56	0.55	0.52	0.59	1.00	0.61	0.57	0.59	0.62	0.54	0.57	0.55	0.59	0.60
2099 (ESR1)	0.52	1.00	0.53	0.55	0.51	1.00	0.48	0.45	0.53	0.61	0.60	0.47	0.74	0.48	0.62	0.56	0.61	1.00	0.47	0.51	0.51	0.50	0.47	0.47	0.48	0.53
5600 (MAPK11)	0.51	1.00	0.55	0.54	0.61	1.00	0.85	0.88	0.70	0.59	0.56	0.87	0.50	0.43	0.42	0.55	0.57	0.47	1.00	0.48	0.90	0.46	1.00	0.44	0.48	0.84
6233 (RPS27A)	0.77	1.00	0.83	0.65	0.69	1.00	0.44	0.44	0.44	0.59	0.71	0.47	0.57	0.54	0.66	0.63	0.59	0.51	0.48	1.00	0.51	0.78	0.48	0.59	0.57	0.51
5596 (MAPK4)	0.52	1.00	0.57	0.56	0.61	1.00	0.81	0.83	0.70	0.64	0.67	0.83	0.54	0.47	0.45	0.56	0.62	0.51	0.90	0.51	1.00	0.48	0.90	0.47	0.52	0.84
26986 (PABPC1)	0.79	1.00	0.83	0.69	0.57	1.00	0.43	0.43	0.44	0.56	0.74	0.46	0.61	0.54	0.71	0.66	0.54	0.50	0.46	0.78	0.48	1.00	0.46	0.48	0.51	0.49
5597 (MAPK6)	0.51	1.00	0.55	0.54	0.61	1.00	0.85	0.88	0.70	0.59	0.56	0.87	0.50	0.43	0.42	0.55	0.57	0.47	1.00	0.48	0.90	0.46	1.00	0.44	0.48	0.84
58 (ACTA1)	0.68	1.00	0.56	0.67	0.58	1.00	0.42	0.42	0.57	0.56	0.57	0.45	0.57	0.47	0.45	0.65	0.55	0.47	0.44	0.59	0.47	0.48	0.44	1.00	0.83	0.48
3308 (HSPA4)	0.68	1.00	0.66	0.68	0.74	1.00	0.42	0.43	0.56	0.59	0.62	0.47	0.56	0.50	0.46	0.66	0.59	0.48	0.48	0.57	0.52	0.51	0.48	0.83	1.00	0.51
1432 (MAPK14)	0.52	1.00	0.57	0.58	0.58	1.00	0.79	0.85	0.72	0.65	0.59	0.84	0.57	0.48	0.46	0.59	0.60	0.53	0.84	0.51	0.84	0.49	0.84	0.48	0.51	1.00

Association with High Altitude

Protein Official symbol	Source Organism	Tissue of Expression	Level of hypoxia	Altitude	Duration of experiment	Level of expression	Fold change	Experiment details	geographical location	ethnicity of the patients	Control group	Control (Fold change)	Reference (PMID)
HSPB1	Human	Skeletal muscle	-	4559 m	9 day	downregulated	-1.35	2-DIGE	Southern Europe	Italians	1	Fasting control subjects at laboratory in Copenhagen with no caffeine intake	18937252
HSPB1	Human	Blood	-	3600 m	Native	upregulated	-	TMT-based proteomic analysis/LC-MS	Central Asia	Tibetans	-	High altitude native vs. low Lander	30908922
HSPB1	Rat	Brain cortex	300hPa	9144 m	1 hour	downregulated	38.98 ± 0.06	2-DE	Southwestern europe	Male wistar rats	0	adult male wistar rats weighing 350 g	25064252
HSPB1	Rat	Lungs	-	7600 m	12 hours	downregulated	-0.8	2-DE	Northern indo-australian plate	Sprague-Dawley	1	Male SD rats weighing 220g	26022216
HSPB1	Rat	Lungs	-	7600 m	24 hours	upregulated	-0.5	2-DE	Northern indo-australian plate	Sprague-Dawley	1	Male SD rats weighing 220g	26022216

Association with TF

TF	TF Entrez	Gene	Gene Entrez	Type	PMID	Database
EP300	2033	HSPB1	3315	proximal_filtered	22955619	TRANSFAC
ESR1	2099	HSPB1	3315	proximal_filtered	22955619	TRANSFAC
FOXA1	3169	HSPB1	3315	proximal_filtered	22955619	TRANSFAC
STAT3	6774	HSPB1	3315	Unknown	9238003	TRUSST

Association with miRNA

miRTarBase ID	miRNA	Species (miRNA)	Protein Official Symbol	Human Entrez ID	Species (Target Gene)	Experiments	Support Type	References (PMID)

Gene Ontology

ID	GO ID	GO Term	GO Type
3315	GO:0006986	response to unfolded protein	GOTERM_BP_DIRECT
3315	GO:0043130	ubiquitin binding	GOTERM_MF_DIRECT
3315	GO:0010506	regulation of autophagy	GOTERM_BP_DIRECT
3315	GO:0043488	regulation of mRNA stability	GOTERM_BP_DIRECT
3315	GO:0071901	negative regulation of protein serine/threonine kinase activity	GOTERM_BP_DIRECT
3315	GO:0005829	cytosol	GOTERM_CC_DIRECT
3315	GO:0045766	positive regulation of angiogenesis	GOTERM_BP_DIRECT
3315	GO:0001895	retina homeostasis	GOTERM_BP_DIRECT
3315	GO:0009615	response to virus	GOTERM_BP_DIRECT
3315	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	GOTERM_BP_DIRECT
3315	GO:0000502	proteasome complex	GOTERM_CC_DIRECT
3315	GO:0005925	focal adhesion	GOTERM_CC_DIRECT
3315	GO:0005615	extracellular space	GOTERM_CC_DIRECT
3315	GO:2001028	positive regulation of endothelial cell chemotaxis	GOTERM_BP_DIRECT
3315	GO:0008426	sterol 14-demethylase activity	GOTERM_MF_DIRECT
3315	GO:0042802	identical protein binding	GOTERM_MF_DIRECT
3315	GO:0044822	poly	GOTERM_MF_DIRECT
3315	GO:0030018	Z disc	GOTERM_CC_DIRECT
3315	GO:0006928	movement of cell or subcellular component	GOTERM_BP_DIRECT
3315	GO:0035924	cellular response to vascular endothelial growth factor stimulus	GOTERM_BP_DIRECT
3315	GO:0006446	regulation of translational initiation	GOTERM_BP_DIRECT
3315	GO:0019901	protein kinase binding	GOTERM_MF_DIRECT
3315	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process	GOTERM_BP_DIRECT
3315	GO:0005515	protein binding	GOTERM_MF_DIRECT
3315	GO:0006469	negative regulation of protein kinase activity	GOTERM_BP_DIRECT
3315	GO:0032731	positive regulation of interleukin-1 beta production	GOTERM_BP_DIRECT
3315	GO:0031012	extracellular matrix	GOTERM_CC_DIRECT
3315	GO:0070062	extracellular exosome	GOTERM_CC_DIRECT
3315	GO:0043066	negative regulation of apoptotic process	GOTERM_BP_DIRECT
3315	GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	GOTERM_BP_DIRECT
3315	GO:0005856	cytoskeleton	GOTERM_CC_DIRECT
3315	GO:0038033	positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway	GOTERM_BP_DIRECT
3315	GO:0005634	nucleus	GOTERM_CC_DIRECT
3315	GO:0035556	intracellular signal transduction	GOTERM_BP_DIRECT
3315	GO:0043536	positive regulation of blood vessel endothelial cell migration	GOTERM_BP_DIRECT
3315	GO:0070527	platelet aggregation	GOTERM_BP_DIRECT
3315	GO:0005737	cytoplasm	GOTERM_CC_DIRECT
3315	GO:0048010	vascular endothelial growth factor receptor signaling pathway	GOTERM_BP_DIRECT
3315	GO:0005080	receptor signaling protein activity	GOTERM_MF_DIRECT
3315	GO:0005886	plasma membrane	GOTERM_CC_DIRECT
3315	GO:0005819	spindle	GOTERM_CC_DIRECT

Pathways

Human Entrez ID	KEGG ID	KEGG Term
3315	hsa04010	MAPK signaling pathway
3315	hsa04370	VEGF signaling pathway
3315	hsa05146	Amoebiasis

Association with Disease

Protein Official Symbol	Human Entrez ID	Disease Name	Disease Id	Disease Semantic Type	Semantic score	DSI	DPI	Disease Type
HSPB1	3315	Hypertrophic Cardiomyopathy	C0007194	Disease or Syndrome	0.3	0.468	0.69	disease
HSPB1	3315	Squamous cell carcinoma	C0007137	Neoplastic Process	0.37	0.468	0.69	disease
HSPB1	3315	Acute Myeloid Leukemia, M1	C0026998	Neoplastic Process	0.3	0.468	0.69	disease
HSPB1	3315	Heart Failure, Right-Sided	C0235527	Disease or Syndrome	0.3	0.468	0.69	disease
HSPB1	3315	Sarcomatoid Renal Cell Carcinoma	C1266043	Neoplastic Process	0.3	0.468	0.69	disease
HSPB1	3315	Status Epilepticus	C0038220	Disease or Syndrome	0.3	0.468	0.69	disease
HSPB1	3315	Petit mal status	C0270823	Disease or Syndrome	0.3	0.468	0.69	disease
HSPB1	3315	Malignant neoplasm of mouth	C0153381	Neoplastic Process	0.3	0.468	0.69	disease
HSPB1	3315	Hereditary Diffuse Gastric Cancer	C1708349	Neoplastic Process	0.3	0.468	0.69	disease
HSPB1	3315	Myocardial Failure	C1959583	Disease or Syndrome	0.3	0.468	0.69	disease
HSPB1	3315	Congestive heart failure	C0018802	Disease or Syndrome	0.3	0.468	0.69	disease
HSPB1	3315	Conventional (Clear Cell) Renal Cell Carcinoma	C0279702	Neoplastic Process	0.31	0.468	0.69	disease
HSPB1	3315	Liver carcinoma	C2239176	Neoplastic Process	0.4	0.468	0.69	disease
HSPB1	3315	Renal Cell Carcinoma	C0007134	Neoplastic Process	0.32	0.468	0.69	disease
HSPB1	3315	Heart failure	C0018801	Disease or Syndrome	0.3	0.468	0.69	disease
HSPB1	3315	Stomach Neoplasms	C0038356	Neoplastic Process	0.3	0.468	0.69	group
HSPB1	3315	Reperfusion Injury	C0035126	Injury or Poisoning	0.3	0.468	0.69	disease
HSPB1	3315	Malignant neoplasm of tongue	C0153349	Neoplastic Process	0.3	0.468	0.69	disease
HSPB1	3315	HIV Infections	C0019693	Disease or Syndrome	0.32	0.468	0.69	group
HSPB1	3315	Collecting Duct Carcinoma of the Kidney	C1266044	Neoplastic Process	0.3	0.468	0.69	disease
HSPB1	3315	Non-Convulsive Status Epilepticus	C0751523	Disease or Syndrome	0.3	0.468	0.69	disease
HSPB1	3315	Malignant tumor of colon	C0007102	Neoplastic Process	0.31	0.468	0.69	disease
HSPB1	3315	Left-Sided Heart Failure	C0023212	Disease or Syndrome	0.3	0.468	0.69	disease
HSPB1	3315	Mouth Neoplasms	C0026640	Neoplastic Process	0.3	0.468	0.69	group
HSPB1	3315	Multiple Myeloma	C0026764	Neoplastic Process	0.32	0.468	0.69	disease
HSPB1	3315	Grand Mal Status Epilepticus	C0311335	Disease or Syndrome	0.3	0.468	0.69	disease
HSPB1	3315	Papillary Renal Cell Carcinoma	C1306837	Neoplastic Process	0.3	0.468	0.69	disease
HSPB1	3315	Acute Myeloid Leukemia (AML-M2)	C1879321	Neoplastic Process	0.3	0.468	0.69	disease
HSPB1	3315	Leukemia, Myelocytic, Acute	C0023467	Neoplastic Process	0.32	0.468	0.69	disease
HSPB1	3315	Adenocarcinoma of lung (disorder)	C0152013	Neoplastic Process	0.31	0.468	0.69	disease
HSPB1	3315	Status Epilepticus, Subclinical	C0751522	Disease or Syndrome	0.3	0.468	0.69	disease
HSPB1	3315	Contact Dermatitis	C0011616	Disease or Syndrome	0.3	0.468	0.69	disease
HSPB1	3315	Hyperplasia	C0020507	Pathologic Function	0.3	0.468	0.69	phenotype
HSPB1	3315	Contact hypersensitivity	C0162351	Pathologic Function	0.3	0.468	0.69	phenotype
HSPB1	3315	Complex Partial Status Epilepticus	C0393734	Disease or Syndrome	0.3	0.468	0.69	disease
HSPB1	3315	Chromophobe Renal Cell Carcinoma	C1266042	Neoplastic Process	0.3	0.468	0.69	disease
HSPB1	3315	Colonic Neoplasms	C0009375	Neoplastic Process	0.31	0.468	0.69	group
HSPB1	3315	Malignant neoplasm of stomach	C0024623	Neoplastic Process	0.33	0.468	0.69	disease
HSPB1	3315	HIV Coinfection	C4505456	Disease or Syndrome	0.3	0.468	0.69	disease
HSPB1	3315	Tongue Neoplasms	C0040411	Neoplastic Process	0.3	0.468	0.69	group
HSPB1	3315	Simple Partial Status Epilepticus	C0751524	Disease or Syndrome	0.3	0.468	0.69	disease
HSPB1	3315	Heart Decompensation	C1961112	Pathologic Function	0.3	0.468	0.69	phenotype
HSPB1	3315	CHARCOT-MARIE-TOOTH DISEASE, AXONAL, TYPE 2F	C1847823	Disease or Syndrome	0.75	0.468	0.69	disease
HSPB1	3315	NEURONOPATHY, DISTAL HEREDITARY MOTOR, TYPE IIB	C2608087	Disease or Syndrome	0.6	0.468	0.69	disease
HSPB1	3315	Charcot-Marie-Tooth Disease	C0007959	Disease or Syndrome	0.49	0.468	0.69	disease
HSPB1	3315	Distal Muscular Dystrophies	C0751336	Disease or Syndrome	0.3	0.468	0.69	group
HSPB1	3315	Spinal muscular atrophy, Jerash type	C1854023	Disease or Syndrome	0.3	0.468	0.69	disease
HSPB1	3315	Distal Hereditary Motor Neuropathy, Type II	C3711384	Disease or Syndrome	0.31	0.468	0.69	disease

Association with Drug

Protein Official Symbol	Human Entrez ID	drug_claim_primary_name	drug_name	drug_chembl_id	interaction_types
HSPB1	3315	DIFFERENTIATION INDUCER	None	None	None
HSPB1	3315	DIFFERENTIATION AGENTS	None	None	None
HSPB1	3315	OESTROGENS	None	None	None
HSPB1	3315	OGX-427	None	None	None
HSPB1	3315	OGX-427	None	None	antisense
HSPB1	3315	OGX-427	None	None	inhibitor
HSPB1	3315	PROTEIN KINASE C INHIBITOR	None	None	None
HSPB1	3315	ROFECOXIB	ROFECOXIB	CHEMBL122	None
HSPB1	3315	TYROSINE KINASE INHIBITOR	None	None	None
HSPB1	3315	UREA	UREA	CHEMBL985	None
HSPB1	3315	VASOPRESSIN	VASOPRESSIN	CHEMBL373742	None
HSPB1	3315	VITAMIN C	ASCORBATE	CHEMBL196	None