ALTITUDEOMICSDB

HSP72 heat-shock protein 72 kDa

AltitudeomicsDB

Protein Official symbol	HSPA1A
Aliases	HSPA1B HSP72
Chromosomal Location	6
Length	641
Uniprot ID	P08107
EC number	None
Protein family Information(Pfam)	PF00012;
PDB id	4J8F;6FDT;
InterPro ID	IPR043129;IPR018181;IPR029048;IPR029047;IPR013126;
dbSNP	rs538280104 rs483638

Protein Protein Interaction

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AltitudeomicsDB

Protein 1	Protein 2	Combine Score
STIP1	HSP90AA1	0.999
EIF4G1	PABPC1	0.998
HSPA4	DNAJB1	0.998
HSP90AB1	STIP1	0.997
PTGES3	STIP1	0.997
PTGES3	HSP90AA1	0.996
HSP90AA1	DNAJB1	0.994
UBA52	RPS27A	0.993
STIP1	DNAJB1	0.993
HSPA1A	DNAJB1	0.993
TP53	SIRT1	0.992
HSP90AA1	HSPA4	0.99
HSPA1A	HSP90AA1	0.99
DNAJA1	HSP90AA1	0.99
HSP90AA1	FKBP4	0.99
HSF1	HSP90AA1	0.99
DUSP1	MAPK1	0.988
HSPA5	DNAJB1	0.987
FKBP5	NR3C1	0.987
UBC	UBB	0.985
HSP90AB1	DNAJB1	0.985
EP300	CREBBP	0.984
BAG1	HSPA4	0.984
HSP90AA1	TP53	0.984
DNAJC2	HSPA14	0.984
TP53	CREBBP	0.983
TP53	EP300	0.983
FKBP5	AR	0.982
BAG3	HSPA4	0.982
PTGES3	HSP90AB1	0.982
STIP1	FKBP4	0.981
EP300	SIRT1	0.98
HSPA9	DNAJB1	0.979
DNAJA1	HSPA1A	0.979
BAG1	BAG2	0.979
AR	HSP90AA1	0.979
HSPA4	HSPA9	0.979
HSF1	DNAJB1	0.978
HSPA14	DNAJB6	0.978
HSF1	SIRT1	0.978
HSPA1A	HSPB1	0.977
HSP90AB1	HSP90AA1	0.977
STIP1	HSPA4	0.977
HSPA12A	HSPA4L	0.976
PTGES3	FKBP5	0.976
HSPA4L	DNAJB1	0.976
DNAJC2	HSPA4	0.975
HSPA12A	HSPA4	0.975
HSPA1A	HSP90AB1	0.975
HSPA12A	HSPA9	0.974
BAG2	HSPA4	0.974
HSP90AB1	FKBP4	0.974
DNAJA4	HSPA1A	0.974
HSPA4	ST13	0.973
DNAJA1	HSPH1	0.973
PTGES3	FKBP4	0.973
HSPA1A	DNAJB6	0.972
AR	FKBP4	0.972
MAPK3	DUSP1	0.971
HSF1	HSPA1A	0.971
TP53	MAPK1	0.971
DNAJA1	STIP1	0.971
DNAJA1	HSP90AB1	0.97
PGR	FKBP4	0.97
FKBP5	HSP90AA1	0.97
HSPA1A	STIP1	0.97
HSP90AA1	PGR	0.97
HSPA1A	DNAJA3	0.97
AR	SIRT1	0.969
HSPA14	DNAJB1	0.969
HSP90AA1	NR3C1	0.969
HSPA4	DNAJB6	0.969
BAG5	HSPA4	0.969
HSPH1	HSPA9	0.969
HSPA1A	DNAJA2	0.968
HSPA14	HSPA12A	0.968
NR3C1	FKBP4	0.968
HSPA9	HSPA4L	0.966
HSPA4	HSPA12B	0.966
HSF1	HSP90AB1	0.966
HSP90AB1	DNAJA2	0.965
HSP90AA1	DNAJA2	0.965
HSP90AA1	MAPK3	0.964
HSPA1A	HSPA12B	0.962
HSPA1A	HSPA12A	0.962
DNAJC7	HSPA4	0.961
HSPA9	DNAJB6	0.96
PTGES3	HSPA1A	0.959
HSPA1A	AR	0.959
AR	HSP90AB1	0.959
HSP90AA1	MAPK1	0.959
DNAJA4	HSP90AA1	0.959
HSPA1A	BAG3	0.959
STIP1	DNAJA2	0.959
AR	EP300	0.956
HSPA12A	HSPH1	0.956
FKBP5	NR3C2	0.956
DUSP1	NR3C1	0.956
BAG1	HSPA1A	0.955
HSPA1A	TP53	0.955
TP53	NR3C1	0.955
DNAJA4	HSP90AB1	0.954
HSPA9	HSPA12B	0.954
FKBP5	STIP1	0.953
DNAJA4	STIP1	0.953
HSPA5	DNAJB6	0.953
JAK2	IFNG	0.953
EP300	NR3C1	0.953
HSPH1	HSPA12B	0.952
CREBBP	NR3C1	0.951
HSPA14	HSPA12B	0.949
PGR	MAPK3	0.949
HSPA5	HSPH1	0.948
HSPA1A	BAG2	0.948
HSP90AB1	NR3C1	0.948
BAG5	HSPA5	0.947
TP53	MAPK3	0.946
HSPA5	HSPA4	0.946
AR	CREBBP	0.945
NR3C2	FKBP4	0.945
HSPA12A	HSPA5	0.945
DNAJC2	HSPA9	0.945
DNAJA1	DNAJB1	0.944
FKBP5	HSP90AB1	0.944
STIP1	PGR	0.944
HSPA4L	HSPA12B	0.944
HSPA4L	DNAJB6	0.943
HSPA5	HSPA4L	0.943
HSPA5	HSPA12B	0.943
UBB	HSPB1	0.943
HSPA4	BAG4	0.943
HSP90AA1	HSPA5	0.943
DNAJC2	HSPA4L	0.942
MAPK3	NR3C1	0.942
FKBP5	PGR	0.942
HSP90AA1	EP300	0.942
PTGES3	NR3C1	0.942
HSPA9	ST13	0.942
HSPA1A	ST13	0.941
HSPA14	HSPA4	0.941
DUT	MAPK3	0.941
UBC	TP53	0.94
DNAJC2	HSPA5	0.94
HSP90AA1	UBB	0.94
HSPA1A	NR3C1	0.94
NR3C2	HSP90AA1	0.94
UBC	HSP90AA1	0.94
HSPA14	HSPH1	0.94
PGR	EP300	0.939
DNAJC2	HSPA1A	0.939
HSP90AB1	MAPK3	0.939
BAG3	HSPA5	0.939
HSPA1A	FKBP4	0.939
PTGES3	AR	0.938
DNAJC7	HSPA4L	0.938
HSPA14	HSPA4L	0.938
HSPA1A	HSPA4	0.938
NR3C1	MAPK1	0.938
STIP1	NR3C1	0.937
HSF1	MAPK3	0.936
HSPA1A	HSPH1	0.936
DNAJA1	AR	0.936
HSPA1A	BAG5	0.936
DNAJC7	HSPA1A	0.935
UBB	RPS27A	0.935
HSPA1A	HSPA4L	0.934
DNAJA4	DNAJB1	0.934
HSF1	EP300	0.933
FKBP5	HSPA1A	0.933
DNAJA2	DNAJB1	0.933
HSPA1A	MAPK3	0.933
DNAJA4	DNAJA1	0.933
HSPA1A	UBB	0.933
HSF1	CREBBP	0.932
PTGES3	HSF1	0.932
HSP90AA1	RPS27A	0.932
PGR	MAPK1	0.932
HSPA14	HSPA9	0.932
TP53	DNAJA3	0.931
UBC	RPS27A	0.931
EIF4G1	HSPB1	0.931
BAG3	HSPA9	0.931
DNAJC2	HSPA12B	0.931
DNAJC2	HSPA12A	0.931
HSPA1A	DUSP1	0.93
UBA52	EP300	0.93
HSPA5	ST13	0.93
HSF1	MAPK1	0.93
HSPA5	HSPA9	0.929
HSPA12A	DNAJB1	0.929
HSPA12B	DNAJB1	0.929
PABPC1	RPS27A	0.929
HSPA1A	SIRT1	0.929
JAK2	MAPK3	0.929
HSPA5	BAG4	0.928
BAG2	HSPA9	0.928
BAG1	HSPA9	0.928
BAG1	HSPA5	0.928
HSP90AA1	HSPH1	0.927
HSPA1A	MAPK1	0.927
RPS27A	TP53	0.927
DNAJC7	HSPA9	0.926
HSP90AB1	PGR	0.926
JAK2	MAPK1	0.926
HSP90AB1	MAPK1	0.925
HSPA1A	IFNG	0.925
PTGES3	PGR	0.925
DNAJB1	SIRT1	0.924
UBA52	UBB	0.924
HSPA12B	ST13	0.924
HSP90AA1	DUSP1	0.923
DNAJC7	HSPA5	0.923
DNAJB6	HSPA12B	0.923
JAK2	DNAJA3	0.923
HSPA1A	NR3C2	0.922
HSPA1A	HSPA5	0.922
HSPA1A	CREBBP	0.922
HSP90AA1	IFNG	0.922
CREBBP	DNAJB1	0.922
BAG1	HSPA14	0.921
HSPA14	BAG3	0.921
DNAJA1	DNAJA2	0.921
UBA52	HSPA1A	0.921
HSPA1A	PGR	0.921
EIF4G1	HSPA1A	0.921
BAG2	HSPA5	0.92
HSPA14	ST13	0.92
HSF1	FKBP4	0.92
HSPA14	HSPA5	0.92
DUT	MAPK1	0.92
PABPC1	HSPB1	0.92
UBC	HSPA1A	0.919
DNAJA3	IFNG	0.919
AR	PGR	0.919
DNAJC7	HSPA14	0.919
UBC	UBA52	0.919
HSPA1A	PABPC1	0.919
HSPH1	HSPA4	0.919
JAK2	HSPA1A	0.919
HSPA9	BAG4	0.918
HSPA1A	BAG4	0.918
HSPA12A	BAG4	0.918
DNAJA4	DNAJA2	0.918
DNAJC7	HSPA12A	0.918
FKBP5	MAPK3	0.918
BAG3	HSPA4L	0.918
HSPA12A	ST13	0.917
HSPA1A	HSPA9	0.917
BAG5	HSPA4L	0.917
HSPA1A	RPS27A	0.917
EIF4G1	UBB	0.917
HSPA1A	EP300	0.917
UBB	EP300	0.916
HSP90AB1	NR3C2	0.916
HSPA4L	ST13	0.916
AR	NR3C2	0.916
DUT	HSP90AA1	0.916
HSPA12A	DNAJB6	0.916
BAG2	HSPA4L	0.915
UBB	TP53	0.915
EP300	DNAJB1	0.915
BAG4	HSPA12B	0.915
UBC	EP300	0.914
NR3C2	PGR	0.914
BAG5	HSPA9	0.914
UBA52	PABPC1	0.914
AR	NR3C1	0.914
FKBP5	MAPK1	0.913
HSPA14	BAG5	0.913
NR3C2	NR3C1	0.913
HSPA14	HSPA1A	0.912
DNAJC7	HSPA12B	0.912
PGR	NR3C1	0.912
EP300	FKBP4	0.911
BAG2	HSPA12B	0.911
DUT	HSPA1A	0.911
AR	STIP1	0.911
PTGES3	MAPK3	0.911
UBC	HSPB1	0.91
HSPA14	BAG4	0.91
UBA52	HSP90AA1	0.91
HSPA12A	BAG3	0.909
RPS27A	EP300	0.909
EIF4G1	RPS27A	0.909
HSPH1	HSPA4L	0.908
UBC	PABPC1	0.908
HSPA14	BAG2	0.908
UBA52	TP53	0.908
BAG1	HSPA4L	0.908
PTGES3	MAPK1	0.907
MAPK3	FKBP4	0.907
PTGES3	NR3C2	0.907
HSPA4	HSPA4L	0.907
UBC	EIF4G1	0.907
HSP90AB1	EP300	0.907
HSPA12A	HSPA12B	0.906
PTGES3	EP300	0.906
BAG3	HSPA12B	0.906
MAPK1	FKBP4	0.906
HSPA4L	BAG4	0.905
FKBP5	FKBP4	0.905
HSPA12A	BAG5	0.905
BAG5	HSPA12B	0.905
HSPA4	HSPB1	0.904
PABPC1	UBB	0.904
UBA52	HSPB1	0.904
DNAJA1	HSPA4	0.903
BAG1	HSPA12B	0.903
MAPK3	MAPK1	0.902
DUT	DUSP1	0.902
BAG1	HSPA12A	0.902
EIF4G1	UBA52	0.902
RPS27A	HSPB1	0.901
PTGES3	IFNG	0.901
STIP1	NR3C2	0.901
BAG2	HSPA12A	0.9

Gene Ontology Semantic Similarity

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#	10963 (STIP1)	1981 (EIF4G1)	3308 (HSPA4)	3326 (HSP90AB1)	10728 (PTGES3)	3320 (HSP90AA1)	7311 (UBA52)	3303 (HSPA1A)	7157 (TP53)	3301 (DNAJA1)	3297 (HSF1)	1843 (DUSP1)	3309 (HSPA5)	2289 (FKBP5)	7316 (UBC)	2033 (EP300)	573 (BAG1)	27000 (DNAJC2)	9531 (BAG3)	3313 (HSPA9)	367 (AR)	51182 (HSPA14)	259217 (HSPA12A)	22824 (HSPA4L)	9532 (BAG2)	55466 (DNAJA4)	5595 (MAPK3)	5241 (PGR)	9529 (BAG5)	10808 (HSPH1)	2908 (NR3C1)	7266 (DNAJC7)	3717 (JAK2)	1387 (CREBBP)	4306 (NR3C2)	7314 (UBB)	1854 (DUT)	10294 (DNAJA2)	116835 (HSPA12B)	26986 (PABPC1)	6233 (RPS27A)	3337 (DNAJB1)	10049 (DNAJB6)	9093 (DNAJA3)	9530 (BAG4)	5594 (MAPK1)	23411 (SIRT1)	2288 (FKBP4)	3315 (HSPB1)	6767 (ST13)	3458 (IFNG)
10963 (STIP1)	1.00	0.80	0.66	0.66	0.70	0.59	0.67	0.67	0.57	0.67	0.61	0.45	0.65	0.71	0.79	0.47	0.66	0.71	0.68	0.71	0.58	0.64	0.48	0.24	0.73	0.78	0.56	0.65	0.67	0.67	0.50	0.70	0.55	0.52	0.53	0.67	0.74	0.69	1.00	0.83	0.74	0.65	0.73	1.00	0.80	0.51	0.54	0.79	0.74	0.75	0.75
1981 (EIF4G1)	0.80	1.00	0.69	0.73	0.58	0.69	0.57	0.73	0.63	0.60	0.60	0.47	0.66	0.58	0.76	0.51	0.60	0.71	0.61	0.78	0.59	0.66	0.48	1.00	0.67	0.62	0.55	0.67	0.61	0.60	0.48	0.57	0.57	0.54	0.51	0.57	0.73	0.59	1.00	0.80	0.74	0.58	0.60	1.00	0.78	0.52	0.55	0.75	0.76	0.60	0.60
3308 (HSPA4)	0.66	0.69	1.00	0.64	0.61	0.59	0.62	0.67	0.55	0.64	0.47	0.40	0.73	0.63	0.61	0.41	0.69	0.56	0.71	0.71	0.51	0.75	0.48	1.00	0.76	0.76	0.51	0.54	0.70	0.71	0.40	0.62	0.51	0.45	0.47	0.62	0.52	0.65	1.00	0.51	0.55	0.62	0.68	1.00	0.64	0.47	0.54	0.58	0.62	0.71	0.71
3326 (HSP90AB1)	0.66	0.73	0.64	1.00	0.61	0.89	0.61	0.84	0.69	0.64	0.63	0.55	0.78	0.59	0.68	0.51	0.62	0.65	0.62	0.79	0.61	0.72	0.48	1.00	0.64	0.60	0.57	0.65	0.67	0.59	0.54	0.61	0.60	0.54	0.54	0.61	0.65	0.60	1.00	0.66	0.66	0.63	0.63	1.00	0.68	0.55	0.61	0.65	0.73	0.59	0.59
10728 (PTGES3)	0.70	0.58	0.61	0.61	1.00	0.59	0.64	0.63	0.53	0.67	0.53	0.51	0.68	0.71	0.62	0.47	0.61	0.58	0.62	0.62	0.54	0.64	0.48	0.15	0.70	0.77	0.64	0.58	0.66	0.62	0.48	0.65	0.58	0.51	0.54	0.64	0.57	0.71	1.00	0.55	0.58	0.68	0.74	1.00	0.59	0.61	0.57	0.66	0.62	0.67	0.67
3320 (HSP90AA1)	0.59	0.69	0.59	0.89	0.59	1.00	0.56	0.81	0.66	0.60	0.56	0.50	0.76	0.53	0.62	0.50	0.59	0.59	0.57	0.78	0.56	0.72	0.48	1.00	0.61	0.57	0.61	0.60	0.63	0.56	0.49	0.55	0.67	0.51	0.49	0.56	0.61	0.57	1.00	0.61	0.60	0.57	0.58	1.00	0.64	0.61	0.60	0.59	0.67	0.54	0.54
7311 (UBA52)	0.67	0.57	0.62	0.61	0.64	0.56	1.00	0.64	0.54	0.73	0.49	0.46	0.68	0.67	0.88	0.43	0.76	0.59	0.64	0.65	0.54	0.61	0.64	0.15	0.70	0.76	0.56	0.58	0.75	0.63	0.44	0.66	0.53	0.48	0.54	1.00	0.55	0.68	1.00	0.53	0.84	0.64	0.70	1.00	0.70	0.52	0.55	0.60	0.63	0.73	0.73
3303 (HSPA1A)	0.67	0.73	0.67	0.84	0.63	0.81	0.64	1.00	0.69	0.69	0.59	0.55	0.86	0.62	0.69	0.55	0.65	0.64	0.65	0.87	0.61	0.83	0.48	1.00	0.64	0.65	0.58	0.64	0.66	0.62	0.53	0.62	0.59	0.58	0.56	0.64	0.68	0.62	1.00	0.67	0.67	0.71	0.65	1.00	0.69	0.56	0.65	0.66	0.67	0.62	0.62
7157 (TP53)	0.57	0.63	0.55	0.69	0.53	0.66	0.54	0.69	1.00	0.56	0.77	0.49	0.64	0.51	0.60	0.59	0.54	0.67	0.52	0.61	0.81	0.55	0.48	1.00	0.56	0.54	0.52	0.75	0.58	0.52	0.69	0.51	0.54	0.70	0.60	0.54	0.57	0.53	1.00	0.59	0.58	0.53	0.53	1.00	0.59	0.51	0.61	0.56	0.61	0.52	0.52
3301 (DNAJA1)	0.67	0.60	0.64	0.64	0.67	0.60	0.73	0.69	0.56	1.00	0.53	0.53	0.70	0.68	0.70	0.47	0.76	0.74	0.70	0.66	0.57	0.63	0.48	0.15	0.75	0.74	0.59	0.60	0.78	0.70	0.49	0.81	0.58	0.52	0.58	0.73	0.60	0.83	1.00	0.58	0.67	0.80	0.84	1.00	0.73	0.56	0.57	0.63	0.65	0.69	0.70
3297 (HSF1)	0.61	0.60	0.47	0.63	0.53	0.56	0.49	0.59	0.77	0.53	1.00	0.45	0.56	0.51	0.57	0.56	0.48	0.70	0.49	0.58	0.78	0.52	0.48	0.24	0.54	0.52	0.48	0.80	0.54	0.48	0.73	0.51	0.53	0.70	0.62	0.49	0.54	0.50	1.00	0.58	0.55	0.52	0.54	1.00	0.56	0.47	0.56	0.59	0.64	0.50	0.50
1843 (DUSP1)	0.45	0.47	0.40	0.55	0.51	0.50	0.46	0.55	0.49	0.53	0.45	1.00	0.56	0.47	0.47	0.39	0.43	0.46	0.44	0.50	0.46	0.50	0.48	0.15	0.52	0.52	0.43	0.45	0.53	0.41	0.39	0.44	0.48	0.41	0.37	0.46	0.42	0.48	1.00	0.41	0.43	0.50	0.51	1.00	0.42	0.41	0.56	0.47	0.56	0.47	0.47
3309 (HSPA5)	0.65	0.66	0.73	0.78	0.68	0.76	0.68	0.86	0.64	0.70	0.56	0.56	1.00	0.66	0.68	0.49	0.70	0.61	0.69	0.91	0.58	0.91	0.48	1.00	0.70	0.71	0.60	0.62	0.73	0.65	0.51	0.65	0.57	0.53	0.58	0.68	0.71	0.68	1.00	0.58	0.65	0.70	0.71	1.00	0.68	0.58	0.63	0.64	0.65	0.65	0.65
2289 (FKBP5)	0.71	0.58	0.63	0.59	0.71	0.53	0.67	0.62	0.51	0.68	0.51	0.47	0.66	1.00	0.63	0.44	0.64	0.60	0.65	0.62	0.52	0.65	0.48	0.15	0.71	0.77	0.58	0.56	0.65	0.64	0.44	0.72	0.54	0.48	0.52	0.67	0.56	0.68	1.00	0.53	0.58	0.66	0.74	1.00	0.60	0.54	0.55	0.82	0.63	0.74	0.74
7316 (UBC)	0.79	0.76	0.61	0.68	0.62	0.62	0.88	0.69	0.60	0.70	0.57	0.47	0.68	0.63	1.00	0.48	0.71	0.67	0.62	0.72	0.59	0.60	0.64	0.24	0.68	0.70	0.55	0.66	0.71	0.62	0.48	0.63	0.55	0.53	0.54	0.88	0.68	0.65	1.00	0.77	0.90	0.63	0.66	1.00	0.82	0.52	0.55	0.72	0.70	0.67	0.67
2033 (EP300)	0.47	0.51	0.41	0.51	0.47	0.50	0.43	0.55	0.59	0.47	0.56	0.39	0.49	0.44	0.48	1.00	0.42	0.50	0.42	0.49	0.60	0.45	0.48	0.24	0.45	0.44	0.48	0.54	0.44	0.41	0.46	0.42	0.50	0.79	0.39	0.43	0.45	0.43	1.00	0.50	0.47	0.48	0.45	1.00	0.46	0.48	0.55	0.49	0.49	0.43	0.42
573 (BAG1)	0.66	0.60	0.69	0.62	0.61	0.59	0.76	0.65	0.54	0.76	0.48	0.43	0.70	0.64	0.71	0.42	1.00	0.62	0.88	0.67	0.52	0.63	0.48	0.43	0.88	0.74	0.53	0.57	0.93	0.92	0.42	0.72	0.52	0.46	0.50	0.76	0.54	0.74	1.00	0.52	0.66	0.67	0.75	1.00	0.91	0.49	0.54	0.59	0.63	0.71	0.70
27000 (DNAJC2)	0.71	0.71	0.56	0.65	0.58	0.59	0.59	0.64	0.67	0.74	0.70	0.46	0.61	0.60	0.67	0.50	0.62	1.00	0.63	0.64	0.73	0.58	0.48	0.24	0.66	0.64	0.52	0.73	0.63	0.62	0.63	0.75	0.56	0.62	0.68	0.59	0.63	0.74	1.00	0.71	0.64	0.74	0.76	1.00	0.70	0.50	0.57	0.67	0.67	0.61	0.61
9531 (BAG3)	0.68	0.61	0.71	0.62	0.62	0.57	0.64	0.65	0.52	0.70	0.49	0.44	0.69	0.65	0.62	0.42	0.88	0.63	1.00	0.62	0.52	0.64	0.48	0.43	0.89	0.76	0.54	0.56	0.84	0.94	0.42	0.74	0.52	0.47	0.51	0.64	0.55	0.75	1.00	0.53	0.57	0.74	0.76	1.00	0.81	0.50	0.54	0.60	0.63	0.72	0.72
3313 (HSPA9)	0.71	0.78	0.71	0.79	0.62	0.78	0.65	0.87	0.61	0.66	0.58	0.50	0.91	0.62	0.72	0.49	0.67	0.64	0.62	1.00	0.57	0.94	0.48	1.00	0.65	0.66	0.54	0.61	0.68	0.61	0.49	0.61	0.54	0.52	0.52	0.65	0.72	0.63	1.00	0.70	0.70	0.62	0.66	1.00	0.74	0.52	0.58	0.69	0.68	0.61	0.61
367 (AR)	0.58	0.59	0.51	0.61	0.54	0.56	0.54	0.61	0.81	0.57	0.78	0.46	0.58	0.52	0.59	0.60	0.52	0.73	0.52	0.57	1.00	0.53	0.48	0.24	0.55	0.55	0.51	0.85	0.54	0.51	0.84	0.52	0.54	0.74	0.71	0.54	0.55	0.53	1.00	0.58	0.57	0.56	0.54	1.00	0.57	0.50	0.62	0.57	0.59	0.53	0.54
51182 (HSPA14)	0.64	0.66	0.75	0.72	0.64	0.72	0.61	0.83	0.55	0.63	0.52	0.50	0.91	0.65	0.60	0.45	0.63	0.58	0.64	0.94	0.53	1.00	0.48	1.00	0.68	0.70	0.55	0.56	0.65	0.64	0.46	0.64	0.53	0.49	0.53	0.61	0.66	0.65	1.00	0.54	0.57	0.64	0.69	1.00	0.61	0.52	0.58	0.62	0.63	0.64	0.64
259217 (HSPA12A)	0.48	0.48	0.48	0.48	0.48	0.48	0.64	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.64	0.48	0.48	0.48	0.48	0.48	0.48	0.48	1.00	0.10	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.64	0.48	0.48	0.48	0.48	0.64	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48
22824 (HSPA4L)	0.24	1.00	1.00	1.00	0.15	1.00	0.15	1.00	1.00	0.15	0.24	0.15	1.00	0.15	0.24	0.24	0.43	0.24	0.43	1.00	0.24	1.00	0.10	1.00	0.43	0.15	0.15	0.24	0.43	0.43	0.20	0.15	0.24	0.21	0.15	0.15	0.24	0.15	0.15	0.24	0.24	0.15	0.15	0.15	0.43	0.15	0.46	0.24	0.24	0.15	0.15
9532 (BAG2)	0.73	0.67	0.76	0.64	0.70	0.61	0.70	0.64	0.56	0.75	0.54	0.52	0.70	0.71	0.68	0.45	0.88	0.66	0.89	0.65	0.55	0.68	0.48	0.43	1.00	0.83	0.63	0.64	0.88	0.92	0.47	0.77	0.58	0.51	0.59	0.70	0.62	0.82	1.00	0.59	0.63	0.74	0.82	1.00	0.82	0.59	0.58	0.65	0.70	0.77	0.76
55466 (DNAJA4)	0.78	0.62	0.76	0.60	0.77	0.57	0.76	0.65	0.54	0.74	0.52	0.52	0.71	0.77	0.70	0.44	0.74	0.64	0.76	0.66	0.55	0.70	0.48	0.15	0.83	1.00	0.62	0.62	0.78	0.77	0.46	0.77	0.56	0.50	0.61	0.76	0.64	0.88	1.00	0.60	0.65	0.76	0.87	1.00	0.69	0.57	0.55	0.67	0.68	0.87	0.86
5595 (MAPK3)	0.56	0.55	0.51	0.57	0.64	0.61	0.56	0.58	0.52	0.59	0.48	0.43	0.60	0.58	0.55	0.48	0.53	0.52	0.54	0.54	0.51	0.55	0.48	0.15	0.63	0.62	1.00	0.55	0.56	0.52	0.42	0.54	0.73	0.49	0.47	0.56	0.49	0.57	1.00	0.48	0.51	0.57	0.59	1.00	0.51	0.99	0.55	0.55	0.60	0.58	0.58
5241 (PGR)	0.65	0.67	0.54	0.65	0.58	0.60	0.58	0.64	0.75	0.60	0.80	0.45	0.62	0.56	0.66	0.54	0.57	0.73	0.56	0.61	0.85	0.56	0.48	0.24	0.64	0.62	0.55	1.00	0.60	0.55	0.76	0.56	0.55	0.66	0.71	0.58	0.58	0.58	1.00	0.64	0.61	0.62	0.60	1.00	0.63	0.52	0.62	0.62	0.67	0.59	0.59
9529 (BAG5)	0.67	0.61	0.70	0.67	0.66	0.63	0.75	0.66	0.58	0.78	0.54	0.53	0.73	0.65	0.71	0.44	0.93	0.63	0.84	0.68	0.54	0.65	0.48	0.43	0.88	0.78	0.56	0.60	1.00	0.86	0.49	0.72	0.58	0.49	0.54	0.75	0.58	0.77	1.00	0.55	0.67	0.71	0.78	1.00	0.87	0.52	0.58	0.61	0.72	0.71	0.70
10808 (HSPH1)	0.67	0.60	0.71	0.59	0.62	0.56	0.63	0.62	0.52	0.70	0.48	0.41	0.65	0.64	0.62	0.41	0.92	0.62	0.94	0.61	0.51	0.64	0.48	0.43	0.92	0.77	0.52	0.55	0.86	1.00	0.41	0.75	0.51	0.45	0.48	0.63	0.53	0.76	1.00	0.52	0.55	0.68	0.77	1.00	0.83	0.47	0.53	0.59	0.63	0.73	0.73
2908 (NR3C1)	0.50	0.48	0.40	0.54	0.48	0.49	0.44	0.53	0.69	0.49	0.73	0.39	0.51	0.44	0.48	0.46	0.42	0.63	0.42	0.49	0.84	0.46	0.48	0.20	0.47	0.46	0.42	0.76	0.49	0.41	1.00	0.43	0.47	0.59	0.71	0.44	0.43	0.44	1.00	0.45	0.46	0.47	0.47	1.00	0.45	0.40	0.56	0.48	0.54	0.43	0.43
7266 (DNAJC7)	0.70	0.57	0.62	0.61	0.65	0.55	0.66	0.62	0.51	0.81	0.51	0.44	0.65	0.72	0.63	0.42	0.72	0.75	0.74	0.61	0.52	0.64	0.48	0.15	0.77	0.77	0.54	0.56	0.72	0.75	0.43	1.00	0.53	0.47	0.52	0.66	0.54	0.92	1.00	0.53	0.57	0.81	0.95	1.00	0.67	0.50	0.53	0.64	0.64	0.73	0.73
3717 (JAK2)	0.55	0.57	0.51	0.60	0.58	0.67	0.53	0.59	0.54	0.58	0.53	0.48	0.57	0.54	0.55	0.50	0.52	0.56	0.52	0.54	0.54	0.53	0.48	0.24	0.58	0.56	0.73	0.55	0.58	0.51	0.47	0.53	1.00	0.50	0.47	0.53	0.51	0.55	1.00	0.53	0.53	0.55	0.56	1.00	0.53	0.73	0.57	0.55	0.63	0.54	0.55
1387 (CREBBP)	0.52	0.54	0.45	0.54	0.51	0.51	0.48	0.58	0.70	0.52	0.70	0.41	0.53	0.48	0.53	0.79	0.46	0.62	0.47	0.52	0.74	0.49	0.48	0.21	0.51	0.50	0.49	0.66	0.49	0.45	0.59	0.47	0.50	1.00	0.56	0.48	0.48	0.48	1.00	0.51	0.50	0.54	0.50	1.00	0.50	0.48	0.59	0.52	0.53	0.48	0.48
4306 (NR3C2)	0.53	0.51	0.47	0.54	0.54	0.49	0.54	0.56	0.60	0.58	0.62	0.37	0.58	0.52	0.54	0.39	0.50	0.68	0.51	0.52	0.71	0.53	0.48	0.15	0.59	0.61	0.47	0.71	0.54	0.48	0.71	0.52	0.47	0.56	1.00	0.54	0.44	0.55	1.00	0.45	0.49	0.56	0.58	1.00	0.48	0.44	0.54	0.51	0.55	0.56	0.56
7314 (UBB)	0.67	0.57	0.62	0.61	0.64	0.56	1.00	0.64	0.54	0.73	0.49	0.46	0.68	0.67	0.88	0.43	0.76	0.59	0.64	0.65	0.54	0.61	0.64	0.15	0.70	0.76	0.56	0.58	0.75	0.63	0.44	0.66	0.53	0.48	0.54	1.00	0.55	0.68	1.00	0.53	0.84	0.64	0.70	1.00	0.70	0.52	0.55	0.60	0.63	0.73	0.73
1854 (DUT)	0.74	0.73	0.52	0.65	0.57	0.61	0.55	0.68	0.57	0.60	0.54	0.42	0.71	0.56	0.68	0.45	0.54	0.63	0.55	0.72	0.55	0.66	0.48	0.24	0.62	0.64	0.49	0.58	0.58	0.53	0.43	0.54	0.51	0.48	0.44	0.55	1.00	0.58	1.00	0.73	0.64	0.57	0.61	1.00	0.67	0.45	0.54	0.68	0.67	0.59	0.59
10294 (DNAJA2)	0.69	0.59	0.65	0.60	0.71	0.57	0.68	0.62	0.53	0.83	0.50	0.48	0.68	0.68	0.65	0.43	0.74	0.74	0.75	0.63	0.53	0.65	0.48	0.15	0.82	0.88	0.57	0.58	0.77	0.76	0.44	0.92	0.55	0.48	0.55	0.68	0.58	1.00	1.00	0.56	0.60	0.85	0.98	1.00	0.69	0.53	0.54	0.62	0.66	0.75	0.74
116835 (HSPA12B)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.48	0.15	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00
26986 (PABPC1)	0.83	0.80	0.51	0.66	0.55	0.61	0.53	0.67	0.59	0.58	0.58	0.41	0.58	0.53	0.77	0.50	0.52	0.71	0.53	0.70	0.58	0.54	0.48	0.24	0.59	0.60	0.48	0.64	0.55	0.52	0.45	0.53	0.53	0.51	0.45	0.53	0.73	0.56	1.00	1.00	0.73	0.56	0.58	1.00	0.77	0.46	0.52	0.75	0.73	0.56	0.56
6233 (RPS27A)	0.74	0.74	0.55	0.66	0.58	0.60	0.84	0.67	0.58	0.67	0.55	0.43	0.65	0.58	0.90	0.47	0.66	0.64	0.57	0.70	0.57	0.57	0.64	0.24	0.63	0.65	0.51	0.61	0.67	0.55	0.46	0.57	0.53	0.50	0.49	0.84	0.64	0.60	1.00	0.73	1.00	0.59	0.62	1.00	0.77	0.48	0.53	0.68	0.67	0.61	0.61
3337 (DNAJB1)	0.65	0.58	0.62	0.63	0.68	0.57	0.64	0.71	0.53	0.80	0.52	0.50	0.70	0.66	0.63	0.48	0.67	0.74	0.74	0.62	0.56	0.64	0.48	0.15	0.74	0.76	0.57	0.62	0.71	0.68	0.47	0.81	0.55	0.54	0.56	0.64	0.57	0.85	1.00	0.56	0.59	1.00	0.87	1.00	0.65	0.54	0.60	0.62	0.64	0.67	0.67
10049 (DNAJB6)	0.73	0.60	0.68	0.63	0.74	0.58	0.70	0.65	0.53	0.84	0.54	0.51	0.71	0.74	0.66	0.45	0.75	0.76	0.76	0.66	0.54	0.69	0.48	0.15	0.82	0.87	0.59	0.60	0.78	0.77	0.47	0.95	0.56	0.50	0.58	0.70	0.61	0.98	1.00	0.58	0.62	0.87	1.00	1.00	0.71	0.55	0.55	0.67	0.67	0.76	0.75
9093 (DNAJA3)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.48	0.15	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00
9530 (BAG4)	0.80	0.78	0.64	0.68	0.59	0.64	0.70	0.69	0.59	0.73	0.56	0.42	0.68	0.60	0.82	0.46	0.91	0.70	0.81	0.74	0.57	0.61	0.48	0.43	0.82	0.69	0.51	0.63	0.87	0.83	0.45	0.67	0.53	0.50	0.48	0.70	0.67	0.69	1.00	0.77	0.77	0.65	0.71	1.00	1.00	0.48	0.53	0.71	0.70	0.65	0.65
5594 (MAPK1)	0.51	0.52	0.47	0.55	0.61	0.61	0.52	0.56	0.51	0.56	0.47	0.41	0.58	0.54	0.52	0.48	0.49	0.50	0.50	0.52	0.50	0.52	0.48	0.15	0.59	0.57	0.99	0.52	0.52	0.47	0.40	0.50	0.73	0.48	0.44	0.52	0.45	0.53	1.00	0.46	0.48	0.54	0.55	1.00	0.48	1.00	0.54	0.52	0.57	0.53	0.53
23411 (SIRT1)	0.54	0.55	0.54	0.61	0.57	0.60	0.55	0.65	0.61	0.57	0.56	0.56	0.63	0.55	0.55	0.55	0.54	0.57	0.54	0.58	0.62	0.58	0.48	0.46	0.58	0.55	0.55	0.62	0.58	0.53	0.56	0.53	0.57	0.59	0.54	0.55	0.54	0.54	1.00	0.52	0.53	0.60	0.55	1.00	0.53	0.54	1.00	0.55	0.59	0.54	0.54
2288 (FKBP4)	0.79	0.75	0.58	0.65	0.66	0.59	0.60	0.66	0.56	0.63	0.59	0.47	0.64	0.82	0.72	0.49	0.59	0.67	0.60	0.69	0.57	0.62	0.48	0.24	0.65	0.67	0.55	0.62	0.61	0.59	0.48	0.64	0.55	0.52	0.51	0.60	0.68	0.62	1.00	0.75	0.68	0.62	0.67	1.00	0.71	0.52	0.55	1.00	0.69	0.71	0.64
3315 (HSPB1)	0.74	0.76	0.62	0.73	0.62	0.67	0.63	0.67	0.61	0.65	0.64	0.56	0.65	0.63	0.70	0.49	0.63	0.67	0.63	0.68	0.59	0.63	0.48	0.24	0.70	0.68	0.60	0.67	0.72	0.63	0.54	0.64	0.63	0.53	0.55	0.63	0.67	0.66	1.00	0.73	0.67	0.64	0.67	1.00	0.70	0.57	0.59	0.69	1.00	0.66	0.66
6767 (ST13)	0.75	0.60	0.71	0.59	0.67	0.54	0.73	0.62	0.52	0.69	0.50	0.47	0.65	0.74	0.67	0.43	0.71	0.61	0.72	0.61	0.53	0.64	0.48	0.15	0.77	0.87	0.58	0.59	0.71	0.73	0.43	0.73	0.54	0.48	0.56	0.73	0.59	0.75	1.00	0.56	0.61	0.67	0.76	1.00	0.65	0.53	0.54	0.71	0.66	1.00	0.85
3458 (IFNG)	0.75	0.60	0.71	0.59	0.67	0.54	0.73	0.62	0.52	0.70	0.50	0.47	0.65	0.74	0.67	0.42	0.70	0.61	0.72	0.61	0.54	0.64	0.48	0.15	0.76	0.86	0.58	0.59	0.70	0.73	0.43	0.73	0.55	0.48	0.56	0.73	0.59	0.74	1.00	0.56	0.61	0.67	0.75	1.00	0.65	0.53	0.54	0.64	0.66	0.85	1.00

Association with High Altitude

Protein Official symbol	Source Organism	Tissue of Expression	Level of hypoxia	Altitude	Duration of experiment	Level of expression	Fold change	Experiment details	geographical location	ethnicity of the patients	Control group	Control (Fold change)	Reference (PMID)
HSPA1A	Rat	Lungs	3-10% Oxygen	5800 m	2 hours	upregulated	-	-	-	-	-	Soldier exposed to high altitude compared to their low altitude profile	http://dx.doi.org/10.4172/jpb.S3-004
HSPA1A	Rat	Brain cortex	316 hPa	8810 m	1 hour	downregulated	4.25 ± 0.06	2-DE	Southwestern europe	Male albino wistar Rat	12.78 ± 0.07	Adult male albino Wistar rats weighing 350 g kept at standard conditions	22961459

Association with TF

TF	TF Entrez	Gene	Gene Entrez	Type	PMID	Database
SIRT6	51548	HSPA1A	3303	proximal_filtered	22955619	TRANSFAC
CCNT2	905	HSPA1A	3303	proximal_filtered	22955619	TRANSFAC
NFYB	4801	HSPA1A	3303	proximal_filtered	22955619	TRANSFAC
EP300	2033	HSPA1A	3303	proximal_filtered	22955619	TRANSFAC
GTF2B	2959	HSPA1A	3303	proximal_filtered	22955619	TRANSFAC
TBP	6908	HSPA1A	3303	proximal_filtered	22955619	TRANSFAC
HSF1	3297	HSPA1A	3303	proximal_filtered	22955619	TRANSFAC
FOXA1	3169	HSPA1A	3303	Unknown	11579131	TRUSST
XBP1	7494	HSPA1A	3303	Unknown	11579131	TRUSST

Association with miRNA

miRTarBase ID	miRNA	Species (miRNA)	Protein Official Symbol	Human Entrez ID	Species (Target Gene)	Experiments	Support Type	References (PMID)
MIRT000866	hsa-miR-15a-5p	Homo sapiens	HSPA1A	3303	Homo sapiens	Microarray	Functional MTI (Weak)	18362358
MIRT001456	hsa-miR-16-5p	Homo sapiens	HSPA1A	3303	Homo sapiens	Microarray	Functional MTI (Weak)	18362358
MIRT001456	hsa-miR-16-5p	Homo sapiens	HSPA1A	3303	Homo sapiens	pSILAC//Proteomics	Functional MTI (Weak)	18668040
MIRT018150	hsa-miR-335-5p	Homo sapiens	HSPA1A	3303	Homo sapiens	Microarray	Functional MTI (Weak)	18185580
MIRT021244	hsa-miR-146a-5p	Homo sapiens	HSPA1A	3303	Homo sapiens	Microarray	Functional MTI (Weak)	18057241
MIRT025302	hsa-miR-34a-5p	Homo sapiens	HSPA1A	3303	Homo sapiens	Proteomics	Functional MTI (Weak)	21566225
MIRT100357	hsa-miR-4682	Homo sapiens	HSPA1A	3303	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT100353	hsa-miR-223-5p	Homo sapiens	HSPA1A	3303	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT100356	hsa-miR-4424	Homo sapiens	HSPA1A	3303	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT525027	hsa-miR-6735-3p	Homo sapiens	HSPA1A	3303	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT525028	hsa-miR-595	Homo sapiens	HSPA1A	3303	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT525026	hsa-miR-496	Homo sapiens	HSPA1A	3303	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620

Gene Ontology

ID	GO ID	GO Term	GO Type
3303	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway	GOTERM_BP_DIRECT
3303	GO:0042026	protein refolding	GOTERM_BP_DIRECT
3303	GO:0070370	cellular heat acclimation	GOTERM_BP_DIRECT
3303	GO:0001618	beta-amyloid binding	GOTERM_MF_DIRECT
3303	GO:0048471	perinuclear region of cytoplasm	GOTERM_CC_DIRECT
3303	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	GOTERM_BP_DIRECT
3303	GO:0034605	cellular response to heat	GOTERM_BP_DIRECT
3303	GO:0042826	histone deacetylase binding	GOTERM_MF_DIRECT
3303	GO:0005925	focal adhesion	GOTERM_CC_DIRECT
3303	GO:0031397	negative regulation of protein ubiquitination	GOTERM_BP_DIRECT
3303	GO:0043488	regulation of mRNA stability	GOTERM_BP_DIRECT
3303	GO:0051092	positive regulation of NF-kappaB transcription factor activity	GOTERM_BP_DIRECT
3303	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	GOTERM_BP_DIRECT
3303	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	GOTERM_BP_DIRECT
3303	GO:0001664	virus receptor activity	GOTERM_MF_DIRECT
3303	GO:0046034	ATP metabolic process	GOTERM_BP_DIRECT
3303	GO:0090084	negative regulation of inclusion body assembly	GOTERM_BP_DIRECT
3303	GO:0016887	ATPase activity	GOTERM_MF_DIRECT
3303	GO:0055131	D-glucose transmembrane transporter activity	GOTERM_MF_DIRECT
3303	GO:0031625	ubiquitin protein ligase binding	GOTERM_MF_DIRECT
3303	GO:0044183	protein binding involved in protein folding	GOTERM_MF_DIRECT
3303	GO:0005913	cell-cell adherens junction	GOTERM_CC_DIRECT
3303	GO:0098609	cell-cell adhesion	GOTERM_BP_DIRECT
3303	GO:1902380	positive regulation of endoribonuclease activity	GOTERM_BP_DIRECT
3303	GO:0031396	regulation of protein ubiquitination	GOTERM_BP_DIRECT
3303	GO:0050821	protein stabilization	GOTERM_BP_DIRECT
3303	GO:0098641	cadherin binding involved in cell-cell adhesion	GOTERM_MF_DIRECT
3303	GO:0005737	cytoplasm	GOTERM_CC_DIRECT
3303	GO:0005515	protein binding	GOTERM_MF_DIRECT
3303	GO:0051082	unfolded protein binding	GOTERM_MF_DIRECT
3303	GO:0072562	blood microparticle	GOTERM_CC_DIRECT
3303	GO:0070434	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	GOTERM_BP_DIRECT
3303	GO:1900034	regulation of cellular response to heat	GOTERM_BP_DIRECT
3303	GO:0034599	cellular response to oxidative stress	GOTERM_BP_DIRECT
3303	GO:0060548	negative regulation of cell death	GOTERM_BP_DIRECT
3303	GO:0005814	centriole	GOTERM_CC_DIRECT
3303	GO:0010941	regulation of cell death	GOTERM_BP_DIRECT
3303	GO:0005102	receptor binding	GOTERM_MF_DIRECT
3303	GO:0005524	ATP binding	GOTERM_MF_DIRECT
3303	GO:0005654	nucleoplasm	GOTERM_CC_DIRECT
3303	GO:0005739	mitochondrion	GOTERM_CC_DIRECT
3303	GO:0005829	cytosol	GOTERM_CC_DIRECT
3303	GO:0016234	inclusion body	GOTERM_CC_DIRECT
3303	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	GOTERM_BP_DIRECT
3303	GO:0046718	viral entry into host cell	GOTERM_BP_DIRECT
3303	GO:0042623	lipid phosphatase activity	GOTERM_MF_DIRECT
3303	GO:0000151	ubiquitin ligase complex	GOTERM_CC_DIRECT
3303	GO:0010628	positive regulation of gene expression	GOTERM_BP_DIRECT
3303	GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	GOTERM_BP_DIRECT
3303	GO:0019899	enzyme binding	GOTERM_MF_DIRECT
3303	GO:0031072	troponin T binding	GOTERM_MF_DIRECT
3303	GO:0032757	positive regulation of interleukin-8 production	GOTERM_BP_DIRECT
3303	GO:1904722	positive regulation of mRNA endonucleolytic cleavage involved in unfolded protein response	GOTERM_BP_DIRECT

Pathways

Human Entrez ID	KEGG ID	KEGG Term
3303	hsa03040	Spliceosome
3303	hsa04010	MAPK signaling pathway
3303	hsa04141	Protein processing in endoplasmic reticulum
3303	hsa04144	Endocytosis
3303	hsa04612	Antigen processing and presentation
3303	hsa04915	Estrogen signaling pathway
3303	hsa05162	Measles
3303	hsa05134	Legionellosis
3303	hsa05164	Influenza A
3303	hsa05145	Toxoplasmosis

Association with Disease

Protein Official Symbol	Human Entrez ID	Disease Name	Disease Id	Disease Semantic Type	Semantic score	DSI	DPI	Disease Type
HSPA1A	3303	Reperfusion Injury	C0035126	Injury or Poisoning	0.3	0.516	0.793	disease
HSPA1A	3303	Neoplasm Metastasis	C0027627	Neoplastic Process	0.34	0.516	0.793	phenotype
HSPA1A	3303	Brain Lacerations	C0272945	Injury or Poisoning	0.3	0.516	0.793	disease
HSPA1A	3303	Drug Allergy	C0013182	Pathologic Function	0.3	0.516	0.793	phenotype
HSPA1A	3303	Malignant neoplasm of prostate	C0376358	Neoplastic Process	0.31	0.516	0.793	disease
HSPA1A	3303	Carcinoma, Pancreatic Ductal	C0887833	Neoplastic Process	0.3	0.516	0.793	disease
HSPA1A	3303	Brain Injuries, Focal	C0452047	Injury or Poisoning	0.3	0.516	0.793	group
HSPA1A	3303	Liver diseases	C0023895	Disease or Syndrome	0.3	0.516	0.793	group
HSPA1A	3303	Acute Kidney Insufficiency	C1565662	Disease or Syndrome	0.3	0.516	0.793	disease
HSPA1A	3303	Heat Stress Disorders	C0282507	Injury or Poisoning	0.3	0.516	0.793	group
HSPA1A	3303	Myocardial Ischemia	C0151744	Disease or Syndrome	0.3	0.516	0.793	disease
HSPA1A	3303	Prostatic Neoplasms	C0033578	Neoplastic Process	0.3	0.516	0.793	group
HSPA1A	3303	Injuries, Acute Brain	C0085742	Injury or Poisoning	0.3	0.516	0.793	group
HSPA1A	3303	Liver Dysfunction	C0086565	Finding	0.3	0.516	0.793	phenotype
HSPA1A	3303	Heat Cramps	C0085592	Injury or Poisoning	0.3	0.516	0.793	disease
HSPA1A	3303	melanoma	C0025202	Neoplastic Process	0.31	0.516	0.793	disease
HSPA1A	3303	Parkinson Disease	C0030567	Disease or Syndrome	0.31	0.516	0.793	disease
HSPA1A	3303	Kidney Failure, Acute	C0022660	Disease or Syndrome	0.32	0.516	0.793	disease
HSPA1A	3303	Acute kidney injury	C2609414	Injury or Poisoning	0.3	0.516	0.793	disease
HSPA1A	3303	Brain Injuries	C0270611	Injury or Poisoning	0.3	0.516	0.793	group
HSPA1A	3303	Familial Ménière disease	C4302111	Disease or Syndrome	0.3	0.516	0.793	disease
HSPA1A	3303	Unipolar Depression	C0041696	Mental or Behavioral Dysfunction	0.32	0.516	0.793	disease
HSPA1A	3303	Schizophrenia	C0036341	Mental or Behavioral Dysfunction	0.36	0.516	0.793	disease
HSPA1A	3303	Major depression, single episode	C0024517	Mental or Behavioral Dysfunction	0.31	0.516	0.793	disease
HSPA1A	3303	Major Depressive Disorder	C1269683	Mental or Behavioral Dysfunction	0.32	0.516	0.793	disease
HSPA1A	3303	Paranoid Schizophrenia	C0036349	Mental or Behavioral Dysfunction	0.31	0.516	0.793	disease

Association with Drug

Protein Official Symbol	Human Entrez ID	drug_claim_primary_name	drug_name	drug_chembl_id	interaction_types
HSPA1A	3303	AIMPILA	None	None	None