ALTITUDEOMICSDB

Cullin 2

AltitudeomicsDB

Protein Official symbol	CUL2
Aliases	CUL2
Chromosomal Location	10
Length	745
Uniprot ID	Q13617
EC number	None
Protein family Information(Pfam)	PF00888;PF10557;
PDB id	4WQO;5N4W;6R6H;6R7F;6R7H;6R7I;6R7N;
InterPro ID	IPR016157;IPR016158;IPR036317;IPR001373;IPR019559;IPR016159;IPR036388;IPR036390;
dbSNP	None

Protein Protein Interaction

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AltitudeomicsDB

Protein 1	Protein 2	Combine Score
DCUN1D1	NEDD8	0.999
COPS5	COPS4	0.999
GPS1	COPS5	0.999
CUL3	KEAP1	0.999
GPS1	COPS6	0.999
TCEB1	VHL	0.999
FBXW7	SKP1	0.999
UBE2M	RBX1	0.999
COPS5	COPS6	0.999
GPS1	COPS8	0.999
TCEB1	TCEB2	0.999
COPS5	COPS3	0.999
COPS8	COPS2	0.999
COPS6	COPS3	0.999
GPS1	COPS2	0.999
COPS8	COPS3	0.999
COPS8	COPS6	0.999
CUL2	VHL	0.999
TCEB1	RBX1	0.999
UBC	UBE2S	0.999
NEDD8	RBX1	0.999
COPS6	COPS2	0.999
SKP2	SKP1	0.999
CUL2	TCEB2	0.999
GPS1	COPS3	0.999
GPS1	COPS4	0.999
SKP2	RBX1	0.999
TCEB1	CUL2	0.999
COPS5	COPS2	0.999
COPS2	COPS3	0.999
UBA3	UBE2M	0.999
COPS5	COPS8	0.999
ANAPC11	UBE2S	0.999
HIF1A	VHL	0.999
UBA3	NEDD8	0.999
SKP1	RBX1	0.999
CAND1	RBX1	0.999
DCUN1D1	RBX1	0.999
UBE2M	NEDD8	0.999
COPS8	COPS4	0.999
COPS6	COPS4	0.999
COPS2	COPS4	0.999
DCUN1D1	UBE2M	0.999
COPS3	COPS4	0.999
TCEB2	VHL	0.998
TCEB1	HIF1A	0.998
UBE2F	RNF7	0.998
UBE2F	DCUN1D3	0.998
HIF1A	TCEB2	0.998
UBC	UBE2D1	0.998
CUL3	RBX1	0.998
UBC	CDC34	0.998
CUL3	NEDD8	0.997
TCEB1	RNF7	0.997
CUL2	RBX1	0.997
COPS5	CUL3	0.997
UBE2F	UBA3	0.997
TCEB1	SOCS6	0.996
FBXW7	RBX1	0.996
CUL3	UBE2M	0.996
TCEB1	NEDD8	0.996
UBE2F	NEDD8	0.996
RNF7	UBE2M	0.995
CUL3	SKP1	0.995
RBX1	CDC34	0.995
TCEB2	RBX1	0.995
RNF7	NEDD8	0.995
COPS5	SKP1	0.994
ANAPC11	RNF7	0.994
DCUN1D2	UBE2M	0.994
COPS5	NEDD8	0.994
RNF7	SKP1	0.994
CAND1	CUL3	0.993
CUL2	NEDD8	0.993
UBE2F	RBX1	0.993
SKP1	CDC34	0.993
ANAPC11	RBX1	0.993
RNF7	CUL3	0.992
CUL2	RNF7	0.992
CUL3	COPS4	0.992
DCUN1D2	NEDD8	0.992
CAND1	NEDD8	0.991
DCUN1D2	RBX1	0.991
CAND1	RNF7	0.991
DCUN1D1	CUL3	0.991
TCEB1	SOCS1	0.991
TCEB1	CISH	0.99
TCEB1	CUL3	0.99
COPS6	NEDD8	0.99
RNF7	TCEB2	0.99
FBXW8	SKP1	0.989
UBE2F	DCUN1D1	0.989
CUL2	CAND1	0.989
TCEB1	SOCS5	0.989
CUL2	COPS6	0.989
CUL7	FBXW8	0.989
FBXW7	CDC34	0.988
UBE2F	DCUN1D5	0.988
DCUN1D3	UBE2M	0.988
DCUN1D5	UBE2M	0.987
COPS4	NEDD8	0.987
NEDD8	SKP1	0.987
GPS1	CUL3	0.987
UBE2F	CUL3	0.987
DCUN1D2	CUL3	0.986
FBXW8	RBX1	0.986
TCEB1	SKP1	0.986
SOCS1	TCEB2	0.986
CISH	TCEB2	0.986
CAND1	UBE2M	0.986
CUL2	SKP1	0.985
SOCS6	TCEB2	0.985
CUL2	ZER1	0.984
CUL2	COPS5	0.984
CUL2	UBXN7	0.984
UBE2D1	RBX1	0.984
DCUN1D1	RNF7	0.984
TCEB2	NEDD8	0.984
RNF7	CDC34	0.984
CUL7	RBX1	0.983
UBE2D1	ANAPC11	0.983
UBE2D1	UBXN7	0.983
UBA3	RBX1	0.983
CAND1	DCUN1D1	0.983
RBX1	KEAP1	0.983
UBA3	CUL3	0.983
COPS5	RBX1	0.983
TCEB1	ANAPC11	0.982
CUL2	SKP2	0.982
VHL	RBX1	0.982
SKP2	CUL3	0.982
FBXW8	FBXO4	0.982
CAND1	SKP1	0.982
FBXW2	SKP1	0.982
COPS6	CUL3	0.982
COPS8	LRR1	0.981
CUL2	COPS2	0.981
ANAPC11	SKP1	0.981
SKP2	RNF7	0.981
CUL7	SKP1	0.981
DCUN1D3	RBX1	0.981
DCUN1D5	RBX1	0.981
DCUN1D5	NEDD8	0.98
TCEB1	UBXN7	0.98
CUL2	DCUN1D1	0.98
TCEB1	COPS5	0.98
CAND1	DCUN1D3	0.979
UBE2F	DCUN1D2	0.979
FEM1B	COPS6	0.978
UBA3	DCUN1D1	0.978
RNF7	DCUN1D5	0.978
CUL2	COPS8	0.978
UBE2D1	SKP1	0.977
SOCS5	TCEB2	0.977
UBE2S	UBE3A	0.977
CUL2	ZYG11B	0.977
DCUN1D3	NEDD8	0.977
CUL2	FEM1B	0.977
COPS2	CUL3	0.977
UBE2D1	UBE3A	0.977
UBA3	RNF7	0.977
CUL3	CDC34	0.977
CUL3	DCUN1D5	0.976
CUL3	TCEB2	0.976
CUL2	CUL7	0.976
COPS2	NEDD8	0.976
COPS8	FEM1B	0.976
CUL2	CISH	0.976
UBE2S	SKP1	0.975
CUL2	CDC34	0.975
ANAPC11	CUL3	0.975
DCUN1D3	RNF7	0.975
UBXN7	NEDD8	0.975
DCUN1D2	RNF7	0.975
UBE2D1	CUL3	0.975
FBXO4	SKP1	0.975
CUL2	UBE2M	0.974
COPS6	LRR1	0.974
DCUN1D3	CUL3	0.974
FBXW7	SKP2	0.973
SKP2	NEDD8	0.973
LRR1	COPS3	0.973
FBXW2	CUL2	0.973
CUL7	CUL3	0.973
CUL2	COPS3	0.972
UBE2F	CUL2	0.972
FBXW7	CUL3	0.972
UBE2M	SKP1	0.971
UBA3	FBXW8	0.971
COPS5	DCUN1D1	0.971
UBC	COPS5	0.971
COPS8	NEDD8	0.971
UBA3	CDC34	0.971
COPS8	CUL3	0.971
UBE2D1	RNF7	0.971
CUL2	UBA3	0.971
HIF1A	COPS5	0.97
SKP2	CDC34	0.97
TCEB2	SKP1	0.97
CUL2	COMMD1	0.97
UBA3	DCUN1D5	0.969
COPS6	RBX1	0.969
COPS5	SKP2	0.969
CUL7	UBA3	0.969
COPS2	LRR1	0.968
UBE2D1	NEDD8	0.968
FBXW8	SKP2	0.968
CUL2	HIF1A	0.968
CAND1	DCUN1D5	0.968
COPS3	CUL3	0.968
CUL2	LRR1	0.968
ASB2	TCEB2	0.968
COPS5	RNF7	0.967
UBA3	SKP1	0.967
COPS4	RBX1	0.966
ASB2	DCUN1D3	0.966
TCEB1	UBA3	0.966
CUL2	ANAPC11	0.966
UBE2S	RBX1	0.966
RNF7	UBE2S	0.965
UBC	UBE3A	0.965
UBC	ANAPC11	0.965
FBXW2	FBXW8	0.965
UBE2F	CAND1	0.965
COPS2	RBX1	0.965
CUL2	DCUN1D2	0.965
CUL2	DCUN1D5	0.965
CISH	RNF7	0.964
UBXN7	RBX1	0.964
FEM1B	COPS2	0.964
UBC	DCUN1D1	0.964
CUL2	SOCS1	0.964
TCEB1	FEM1B	0.963
GPS1	NEDD8	0.963
CUL2	FBXO4	0.963
CUL2	KEAP1	0.963
CUL2	FEM1C	0.963
TCEB1	ASB2	0.962
CUL2	COPS4	0.962
COPS4	SKP1	0.962
CUL2	GPS1	0.962
CUL7	NEDD8	0.962
CUL2	UBE2D1	0.962
ANAPC11	TCEB2	0.962
ASB2	CISH	0.961
COPS6	SKP1	0.961
UBC	CUL3	0.961
CUL2	FBXW8	0.961
ASB2	CUL2	0.961
CUL2	DCUN1D3	0.96
FBXW2	RBX1	0.96
TCEB1	SKP2	0.96
CAND1	TCEB2	0.96
CUL7	UBE2M	0.96
CUL7	RNF7	0.959
GPS1	RBX1	0.959
CAND1	DCUN1D2	0.959
UBE2S	VHL	0.959
FBXW7	NEDD8	0.959
CUL7	FBXW7	0.959
CAND1	SKP2	0.959
DCUN1D2	UBA3	0.958
TCEB1	CAND1	0.958
CUL2	FBXW7	0.958
CUL2	SOCS6	0.957
CUL2	FEM1A	0.956
ASB2	RNF7	0.956
UBE3A	SKP1	0.956
SKP2	UBE2S	0.956
CUL2	UBE3A	0.956
DCUN1D2	COPS5	0.956
CUL2	UBC	0.955
ANAPC11	CDC34	0.955
HIF1A	UBXN7	0.955
ANAPC11	UBE2M	0.955
COPS5	FBXW7	0.955
COPS5	DCUN1D5	0.954
FBXO4	SKP2	0.954
ANAPC11	SKP2	0.954
SKP2	VHL	0.954
CUL2	CUL3	0.954
CUL2	SOCS5	0.954
LRR1	VHL	0.954
UBC	UBXN7	0.954
CUL2	UBE2S	0.954
FBXW7	RNF7	0.953
RNF7	VHL	0.953
COPS5	VHL	0.953
COPS3	DCUN1D5	0.953
FBXW8	CUL3	0.953
TCEB1	COMMD1	0.953
VHL	NEDD8	0.953
ANAPC11	FBXW7	0.952
UBE2S	CUL3	0.952
FEM1B	TCEB2	0.952
SOCS6	RNF7	0.952
CUL3	UBE3A	0.952
UBE3A	CDC34	0.952
UBC	UBE2M	0.952
CISH	RBX1	0.952
TCEB1	LRR1	0.952
TCEB1	CDC34	0.951
FEM1B	COPS3	0.951
COPS6	SKP2	0.95
FBXW7	FBXO4	0.95
FBXW8	RNF7	0.95
HIF1A	RBX1	0.95
LRR1	TCEB2	0.95
COPS8	RBX1	0.95
FEM1B	FBXW7	0.95
FBXW7	FEM1C	0.95
FBXW7	FEM1A	0.95
UBE2F	SKP1	0.949
UBE3A	RBX1	0.949
CAND1	FBXW7	0.949
COPS8	SKP1	0.949
UBA3	UBE2S	0.949
FBXW8	FBXW7	0.948
COPS5	DCUN1D3	0.948
UBA3	DCUN1D3	0.948
COPS2	DCUN1D5	0.948
LRR1	RBX1	0.948
UBC	HIF1A	0.948
FEM1B	COPS4	0.948
UBC	UBA3	0.948
FBXW7	UBE2S	0.948
UBE2F	ANAPC11	0.948
ASB2	SKP2	0.948
ASB2	UBC	0.948
UBA3	SKP2	0.947
TCEB1	CUL7	0.947
UBC	DCUN1D2	0.947
FBXW8	NEDD8	0.947
ZER1	TCEB2	0.947
HIF1A	NEDD8	0.946
COPS5	FEM1B	0.946
CISH	SKP1	0.945
ANAPC11	FBXW8	0.945
CUL7	SKP2	0.945
UBE2D1	UBA3	0.945
FBXO4	RBX1	0.945
UBC	RBX1	0.945
ASB2	CUL7	0.944
FEM1B	LRR1	0.944
SOCS5	RNF7	0.944
TCEB1	UBE2D1	0.944
FBXW8	CDC34	0.944
FBXW2	SKP2	0.944
VHL	CDC34	0.944
UBC	SKP1	0.943
UBE2F	UBC	0.943
FEM1B	RBX1	0.943
SKP2	TCEB2	0.943
VHL	SKP1	0.943
FBXO4	CDC34	0.943
SOCS6	SOCS5	0.943
SOCS1	RNF7	0.943
CUL7	TCEB2	0.942
GPS1	SKP1	0.942
SKP2	UBE2M	0.941
CISH	CUL3	0.941
DCUN1D3	SKP2	0.941
UBC	VHL	0.941
COPS6	DCUN1D1	0.94
UBE2D1	LRR1	0.94
UBE2M	CDC34	0.94
DCUN1D2	FEM1C	0.94
GPS1	SKP2	0.94
UBC	KEAP1	0.939
UBE2F	CUL7	0.939
CUL3	VHL	0.939
DCUN1D2	FEM1A	0.939
TCEB1	FEM1C	0.939
COPS3	NEDD8	0.938
CUL7	UBE3A	0.938
DCUN1D1	VHL	0.937
TCEB1	FBXW7	0.937
CUL7	ANAPC11	0.937
UBC	NEDD8	0.937
TCEB1	FEM1A	0.937
TCEB1	UBE2S	0.937
LRR1	CUL3	0.937
TCEB2	CDC34	0.936
UBC	RNF7	0.936
SKP2	UBE3A	0.936
RNF7	COPS4	0.936
SOCS1	VHL	0.936
FBXW2	CUL3	0.936
UBE2F	TCEB1	0.935
TCEB2	UBE2M	0.935
FBXW2	CDC34	0.935
TCEB1	DCUN1D1	0.935
HIF1A	COMMD1	0.935
UBE2S	TCEB2	0.935
ANAPC11	UBE3A	0.934
CUL7	CDC34	0.934
TCEB1	COPS4	0.934
UBC	COPS2	0.934
COPS5	FBXW8	0.934
DCUN1D1	SKP1	0.934
ASB2	UBE2D1	0.934
UBE2M	UBE3A	0.934
COMMD1	CUL3	0.934
NEDD8	KEAP1	0.934
FBXW2	RNF7	0.933
UBXN7	DCUN1D1	0.933
CUL7	FBXO4	0.933
FBXW2	FBXO4	0.933
COMMD1	TCEB2	0.933
FEM1B	RNF7	0.933
UBA3	COPS5	0.933
SOCS6	RBX1	0.933
UBC	COMMD1	0.932
CISH	NEDD8	0.932
FBXW7	VHL	0.932
SOCS6	SKP2	0.932
GPS1	RNF7	0.932
UBE2D1	SKP2	0.932
UBE2D1	VHL	0.932
UBC	DCUN1D5	0.931
UBE2F	TCEB2	0.931
COPS5	LRR1	0.931
HIF1A	DCUN1D1	0.931
COPS5	UBE2M	0.931
FBXW7	UBE3A	0.931
COPS6	RNF7	0.931
FBXW2	FBXW7	0.931
UBE2S	UBE2M	0.931
COPS8	SKP2	0.931
RNF7	UBE3A	0.931
FBXO4	NEDD8	0.93
FBXW7	KEAP1	0.93
LRR1	SKP2	0.93
COPS3	RBX1	0.93
COPS5	TCEB2	0.93
HIF1A	UBE2D1	0.93
SKP1	KEAP1	0.93
UBA3	UBE3A	0.929
TCEB1	DCUN1D5	0.929
SOCS5	RBX1	0.929
UBE2F	CDC34	0.929
ASB2	CAND1	0.929
DCUN1D3	DCUN1D5	0.929
ASB2	CUL3	0.929
TCEB1	FBXW8	0.928
TCEB1	COPS6	0.928
DCUN1D1	SKP2	0.928
FBXW7	TCEB2	0.928
SOCS1	RBX1	0.928
UBE2F	SKP2	0.928
UBE2D1	TCEB2	0.927
DCUN1D2	DCUN1D5	0.927
FBXW8	FEM1A	0.927
UBC	COPS6	0.927
FBXW8	FEM1B	0.927
FBXW8	FEM1C	0.927
TCEB1	UBC	0.927
UBE2D1	FBXW7	0.927
FBXW2	FEM1A	0.927
ASB2	SKP1	0.927
ZER1	RBX1	0.927
FBXW2	FEM1B	0.927
FBXW2	FEM1C	0.927
DCUN1D1	TCEB2	0.926
FBXW2	ANAPC11	0.926
COPS8	RNF7	0.926
CAND1	KEAP1	0.926
COPS6	FEM1A	0.926
ASB2	NEDD8	0.926
DCUN1D3	SKP1	0.925
UBE2D1	FBXO4	0.925
ASB2	RBX1	0.925
DCUN1D1	DCUN1D5	0.925
TCEB1	UBE3A	0.925
TCEB1	DCUN1D2	0.925
DCUN1D2	UBE2D1	0.925
COPS5	FBXO4	0.925
UBC	FBXW7	0.925
COPS6	TCEB2	0.925
CISH	SKP2	0.925
TCEB2	UBE3A	0.925
COPS5	FEM1C	0.925
CAND1	CISH	0.925
COPS6	FEM1C	0.925
UBXN7	TCEB2	0.925
SOCS6	CUL3	0.924
CISH	VHL	0.924
COPS2	FEM1C	0.924
CISH	SOCS5	0.924
RNF7	COPS3	0.924
COPS2	FEM1A	0.924
FBXW2	NEDD8	0.924
TCEB1	UBE2M	0.924
COPS8	TCEB2	0.924
ASB2	COPS2	0.924
TCEB1	COPS3	0.924
SOCS1	SOCS5	0.924
UBC	SOCS1	0.924
COPS4	TCEB2	0.924
UBA3	ANAPC11	0.923
DCUN1D2	COPS6	0.923
SOCS6	SKP1	0.923
VHL	UBE2M	0.923
DCUN1D3	DCUN1D1	0.923
FEM1B	NEDD8	0.923
COPS5	FEM1A	0.923
CAND1	FBXW8	0.923
COPS6	FBXW7	0.923
UBE2S	CDC34	0.923
DCUN1D2	DCUN1D3	0.922
SOCS5	SKP2	0.922
SKP2	COPS4	0.922
DCUN1D2	TCEB2	0.922
SOCS1	SKP1	0.922
FBXW8	UBE2S	0.922
CISH	FBXW7	0.922
DCUN1D3	COPS6	0.922
FEM1C	TCEB2	0.922
COPS2	SKP1	0.921
ASB2	SOCS6	0.921
FEM1A	TCEB2	0.921
DCUN1D2	SKP1	0.921
FEM1C	CUL3	0.921
FEM1C	NEDD8	0.921
FEM1A	CUL3	0.921
CISH	FBXW8	0.921
DCUN1D2	SKP2	0.921
COMMD1	SKP1	0.921
CISH	SOCS6	0.921
COPS2	RNF7	0.921
COPS2	DCUN1D1	0.921
UBE2S	KEAP1	0.921
ASB2	SOCS5	0.921
FBXW8	TCEB2	0.921
TCEB1	DCUN1D3	0.92
COPS3	SKP1	0.92
CAND1	COMMD1	0.92
TCEB1	KEAP1	0.92
COMMD1	RBX1	0.92
UBA3	VHL	0.92
SOCS5	CUL3	0.92
UBE2M	KEAP1	0.92
FBXW7	COPS4	0.92
RNF7	RBX1	0.919
UBA3	TCEB2	0.919
CDC34	KEAP1	0.919
CUL7	UBE2S	0.919
FBXW7	UBE2M	0.919
FBXW8	UBE3A	0.919
UBC	FBXW8	0.919
CUL7	SOCS1	0.919
FBXW2	COPS5	0.919
UBE2D1	CDC34	0.918
COPS5	KEAP1	0.918
DCUN1D3	TCEB2	0.918
TCEB1	COPS8	0.917
DCUN1D1	FEM1C	0.917
COPS6	DCUN1D5	0.917
FEM1B	CUL3	0.917
FBXW2	UBC	0.917
SOCS5	SKP1	0.917
UBE2F	UBE2S	0.917
CUL7	UBE2D1	0.917
CISH	LRR1	0.917
UBA3	LRR1	0.917
UBE2D1	FBXW8	0.917
UBE2F	UBE2M	0.916
UBXN7	VHL	0.916
ASB2	FBXW7	0.916
ASB2	SOCS1	0.916
FEM1A	NEDD8	0.916
UBXN7	CUL3	0.916
COPS3	TCEB2	0.916
DCUN1D1	COPS4	0.916
LRR1	FEM1A	0.916
SKP2	KEAP1	0.916
FBXO4	RNF7	0.915
SOCS1	SKP2	0.915
LRR1	RNF7	0.915
COPS5	COMMD1	0.915
ASB2	COPS5	0.915
COPS8	FEM1A	0.915
ASB2	COPS6	0.915
CISH	COPS5	0.915
SOCS1	FBXW7	0.915
UBE2F	UBE3A	0.914
LRR1	COPS4	0.914
UBA3	FBXW7	0.914
TCEB2	KEAP1	0.914
DCUN1D1	FBXW7	0.914
CAND1	VHL	0.914
UBE2D1	KEAP1	0.914
DCUN1D5	SKP1	0.914
FEM1B	FEM1A	0.914
LRR1	NEDD8	0.914
SOCS6	NEDD8	0.914
FBXO4	COPS4	0.914
SKP2	DCUN1D5	0.914
RNF7	KEAP1	0.914
COPS8	FEM1C	0.914
UBE2D1	UBE2M	0.913
FEM1B	VHL	0.913
VHL	KEAP1	0.913
FEM1C	COPS4	0.913
FEM1A	COPS4	0.913
SOCS6	VHL	0.913
FEM1C	RBX1	0.913
UBE2F	ASB2	0.912
COPS8	FBXW7	0.912
DCUN1D2	COPS2	0.912
FBXW8	VHL	0.912
SOCS1	CDC34	0.912
COPS2	SKP2	0.912
UBE2F	VHL	0.912
SOCS1	UBE2S	0.912
FBXW2	VHL	0.912
COPS8	FBXO4	0.912
FEM1B	FEM1C	0.912
FEM1A	RBX1	0.912
CUL7	KEAP1	0.912
SOCS1	FBXW8	0.912
COMMD1	COPS6	0.912
SOCS5	VHL	0.911
CISH	COMMD1	0.911
GPS1	DCUN1D1	0.911
CISH	FEM1B	0.911
CAND1	FBXO4	0.911
CUL7	VHL	0.911
FEM1C	DCUN1D5	0.911
COMMD1	FBXW7	0.911
UBC	COPS8	0.91
SOCS5	NEDD8	0.91
LRR1	FEM1C	0.91
UBA3	KEAP1	0.91
DCUN1D3	COPS4	0.91
UBC	GPS1	0.91
DCUN1D1	FEM1A	0.91
FEM1C	RNF7	0.91
GPS1	COMMD1	0.91
FBXO4	CUL3	0.91
UBE2D1	SOCS1	0.91
UBE2F	CISH	0.91
UBE2D1	DCUN1D1	0.91
GPS1	TCEB2	0.909
UBC	SKP2	0.909
CISH	COPS8	0.909
UBE2F	UBE2D1	0.909
SOCS1	CUL3	0.909
UBC	COPS4	0.909
DCUN1D3	COPS2	0.909
UBC	CUL7	0.909
FBXW2	ASB2	0.909
LRR1	UBE2S	0.909
SOCS1	UBE3A	0.909
ASB2	FBXW8	0.909
FBXW7	COPS3	0.909
FEM1C	UBE2M	0.909
ASB2	CDC34	0.909
TCEB2	DCUN1D5	0.909
FBXW8	SOCS5	0.909
UBE3A	KEAP1	0.908
COMMD1	NEDD8	0.908
UBC	TCEB2	0.908
CAND1	FEM1C	0.908
ASB2	UBA3	0.908
CAND1	FEM1B	0.908
TCEB1	COPS2	0.908
DCUN1D1	COPS3	0.908
CAND1	FEM1A	0.908
CISH	UBE2M	0.908
ASB2	UBE3A	0.908
ANAPC11	VHL	0.908
FEM1B	DCUN1D1	0.908
LRR1	DCUN1D5	0.908
FBXW2	CUL7	0.908
UBE2F	FBXW7	0.908
CISH	KEAP1	0.908
FEM1A	UBE2M	0.908
UBE2F	FEM1C	0.908
ASB2	COPS4	0.908
GPS1	FBXW7	0.908
UBE2D1	UBE2S	0.908
LRR1	KEAP1	0.907
CAND1	LRR1	0.907
RNF7	FEM1A	0.907
UBE2F	FBXW8	0.907
FBXO4	UBE3A	0.907
CISH	GPS1	0.907
FBXW8	COPS2	0.907
CAND1	SOCS6	0.907
FBXW2	UBE2S	0.907
FEM1A	KEAP1	0.907
SOCS6	FBXW8	0.907
COPS8	COMMD1	0.907
COPS2	FBXW7	0.907
COPS2	TCEB2	0.907
SOCS6	FBXW7	0.907
GPS1	DCUN1D5	0.906
GPS1	DCUN1D3	0.906
ASB2	ANAPC11	0.906
COPS8	KEAP1	0.906
FBXW8	UBE2M	0.906
ASB2	FEM1A	0.906
FBXW2	COPS4	0.906
COPS8	DCUN1D1	0.906
SOCS1	KEAP1	0.906
CISH	UBA3	0.906
ANAPC11	SOCS1	0.906
FBXW2	UBE2D1	0.906
FBXW2	COPS6	0.906
LRR1	SKP1	0.906
FBXW8	COPS6	0.906
SOCS5	KEAP1	0.906
FBXW8	COPS4	0.906
FBXW2	UBA3	0.906
CAND1	SOCS5	0.906
COMMD1	COPS4	0.906
SOCS1	LRR1	0.906
FBXW2	COPS2	0.906
SOCS5	LRR1	0.906
LRR1	CDC34	0.906
DCUN1D2	GPS1	0.906
COPS8	DCUN1D3	0.905
SOCS6	COPS5	0.905
FBXO4	UBE2S	0.905
ASB2	VHL	0.905
UBC	LRR1	0.905
COMMD1	RNF7	0.905
DCUN1D2	FEM1B	0.905
VHL	UBE3A	0.905
FBXW2	SOCS1	0.905
ASB2	FEM1C	0.905
ASB2	FEM1B	0.905
GPS1	KEAP1	0.905
DCUN1D1	KEAP1	0.905
GPS1	FBXW8	0.905
FBXW2	CAND1	0.905
ASB2	UBE2S	0.905
SOCS6	DCUN1D5	0.905
FBXW8	KEAP1	0.905
COPS8	DCUN1D5	0.905
UBE2F	FBXO4	0.904
CISH	DCUN1D1	0.904
DCUN1D2	COPS3	0.904
FEM1B	SOCS5	0.904
DCUN1D3	COPS3	0.904
ASB2	UBE2M	0.904
DCUN1D2	FBXW7	0.904
DCUN1D3	KEAP1	0.904
FBXW2	GPS1	0.904
FEM1B	UBE2M	0.904
UBE2F	KEAP1	0.904
ANAPC11	KEAP1	0.904
UBA3	SOCS1	0.904
UBE2F	FEM1B	0.904
TCEB1	FBXW2	0.904
DCUN1D2	COPS4	0.904
FBXW2	TCEB2	0.904
ASB2	COPS8	0.904
UBE2D1	DCUN1D5	0.904
COMMD1	DCUN1D1	0.904
GPS1	FEM1B	0.904
DCUN1D2	KEAP1	0.904
COMMD1	COPS2	0.904
FEM1B	SKP1	0.904
UBE2D1	COMMD1	0.904
ASB2	LRR1	0.903
LRR1	UBE3A	0.903
FEM1C	KEAP1	0.903
DCUN1D3	FBXW8	0.903
DCUN1D3	FBXW7	0.903
UBE2F	SOCS5	0.903
COMMD1	COPS3	0.903
FBXO4	KEAP1	0.903
TCEB1	GPS1	0.903
UBE2F	FEM1A	0.903
LRR1	UBE2M	0.903
UBE2F	LRR1	0.903
SOCS6	COPS2	0.903
CISH	FBXO4	0.903
COPS4	DCUN1D5	0.903
FBXW2	DCUN1D3	0.903
FBXO4	DCUN1D5	0.902
COPS3	KEAP1	0.902
DCUN1D3	FEM1A	0.902
FBXW2	COPS3	0.902
COMMD1	VHL	0.902
FEM1B	SKP2	0.902
DCUN1D3	FEM1B	0.902
FEM1C	SKP1	0.902
FBXW7	DCUN1D5	0.902
COMMD1	LRR1	0.902
DCUN1D3	FEM1C	0.902
SOCS5	FBXW7	0.902
COPS6	KEAP1	0.902
DCUN1D2	UBXN7	0.902
FEM1A	VHL	0.902
SOCS6	COPS8	0.902
SOCS6	COMMD1	0.902
GPS1	FEM1C	0.902
SOCS5	COPS2	0.902
FEM1B	KEAP1	0.902
SOCS6	LRR1	0.902
FBXW2	UBE3A	0.902
FBXO4	UBE2M	0.902
SKP2	COPS3	0.902
COMMD1	DCUN1D5	0.902
FEM1B	FBXO4	0.902
SOCS5	FEM1C	0.902
COMMD1	UBE2M	0.902
COPS4	KEAP1	0.902
FEM1C	VHL	0.902
ASB2	GPS1	0.902
SOCS6	FEM1A	0.902
CUL7	LRR1	0.902
DCUN1D3	SOCS5	0.902
GPS1	FEM1A	0.902
SOCS6	FEM1C	0.902
SOCS5	FEM1A	0.902
UBXN7	DCUN1D5	0.902
FEM1A	SKP1	0.902
UBC	COPS3	0.902
SOCS5	DCUN1D1	0.902
FBXO4	TCEB2	0.902
FBXW2	SOCS5	0.902
HIF1A	DCUN1D5	0.902
COPS2	KEAP1	0.901
FEM1A	DCUN1D5	0.901
SOCS6	FEM1B	0.901
DCUN1D2	SOCS5	0.901
UBE2F	SOCS6	0.901
SOCS6	UBA3	0.901
FEM1A	COPS3	0.901
SKP2	FEM1A	0.901
FBXW2	LRR1	0.901
FBXW8	LRR1	0.901
CISH	COPS6	0.901
COMMD1	SOCS5	0.901
LRR1	FBXW7	0.901
FEM1B	DCUN1D5	0.901
LRR1	DCUN1D1	0.901
FEM1C	SKP2	0.901
DCUN1D5	KEAP1	0.901
DCUN1D2	DCUN1D1	0.901
CISH	DCUN1D5	0.901
COPS5	SOCS5	0.901
COPS8	VHL	0.901
SOCS6	DCUN1D1	0.901
FBXW8	COPS3	0.901
SOCS5	COPS3	0.9
CISH	FEM1C	0.9
SOCS6	DCUN1D3	0.9
HIF1A	DCUN1D2	0.9
UBA3	SOCS5	0.9
SOCS1	FBXO4	0.9
ASB2	COMMD1	0.9
FBXW2	KEAP1	0.9
DCUN1D2	COMMD1	0.9
GPS1	SOCS5	0.9
SOCS6	COPS6	0.9
DCUN1D1	FBXO4	0.9
COPS2	VHL	0.9
ANAPC11	LRR1	0.9
COPS4	VHL	0.9
UBE2F	SOCS1	0.9
FBXW2	UBE2M	0.9
CISH	COPS4	0.9
FBXO4	COPS3	0.9
FBXW2	CISH	0.9
SOCS5	FBXO4	0.9
UBA3	FBXO4	0.9
FBXO4	FEM1C	0.9
DCUN1D3	LRR1	0.9
SOCS6	COPS3	0.9
SOCS6	KEAP1	0.9
UBE2F	FBXW2	0.9
FBXW2	COMMD1	0.9
DCUN1D2	SOCS6	0.9
SOCS5	UBE2M	0.9
UBA3	COMMD1	0.9
FBXW2	DCUN1D1	0.9
ASB2	COPS3	0.9
UBC	FBXO4	0.9
CISH	COPS3	0.9
CISH	DCUN1D3	0.9
LRR1	FBXO4	0.9
FBXW8	DCUN1D5	0.9
COMMD1	UBXN7	0.9
COPS8	SOCS5	0.9
ASB2	DCUN1D5	0.9
CISH	COPS2	0.9
DCUN1D3	COMMD1	0.9
SOCS6	UBE2M	0.9
SOCS6	FBXO4	0.9
COMMD1	FBXO4	0.9
DCUN1D2	CISH	0.9
FBXO4	FEM1A	0.9
FBXO4	VHL	0.9
DCUN1D3	VHL	0.9
CISH	FEM1A	0.9
TCEB1	FBXO4	0.9
DCUN1D2	VHL	0.9
DCUN1D2	FBXO4	0.9
COMMD1	FEM1B	0.9
GPS1	FBXO4	0.9
ANAPC11	FBXO4	0.9
FBXW2	DCUN1D2	0.9
SOCS1	UBE2M	0.9
UBE2F	COMMD1	0.9
DCUN1D2	LRR1	0.9
GPS1	VHL	0.9
COMMD1	FEM1C	0.9
COMMD1	ZER1	0.9
COPS6	VHL	0.9
COMMD1	FEM1A	0.9
FBXW2	DCUN1D5	0.9
COPS8	FBXW8	0.9
FBXW8	COMMD1	0.9
DCUN1D2	FBXW8	0.9
FEM1C	FEM1A	0.9
COPS6	FBXO4	0.9
DCUN1D5	VHL	0.9
COMMD1	KEAP1	0.9
ASB2	DCUN1D1	0.9
DCUN1D3	FBXO4	0.9
FBXW2	COPS8	0.9
COPS3	VHL	0.9
FBXW8	DCUN1D1	0.9
SOCS6	GPS1	0.9
SOCS5	COPS4	0.9
FEM1C	COPS3	0.9
COMMD1	SKP2	0.9
SOCS5	COPS6	0.9
ASB2	DCUN1D2	0.9
SOCS6	COPS4	0.9
ASB2	KEAP1	0.9
SOCS5	DCUN1D5	0.9
ASB2	FBXO4	0.9
COPS2	FBXO4	0.9
DCUN1D2	COPS8	0.9
GPS1	LRR1	0.9
FBXW2	SOCS6	0.9

Gene Ontology Semantic Similarity

Download Tab separated file

#	54165 (DCUN1D1)	10987 (COPS5)	2873 (GPS1)	8452 (CUL3)	6921 (TCEB1)	55294 (FBXW7)	9040 (UBE2M)	10920 (COPS8)	10980 (COPS6)	8453 (CUL2)	7316 (UBC)	4738 (NEDD8)	6502 (SKP2)	9318 (COPS2)	9039 (UBA3)	51529 (ANAPC11)	3091 (HIF1A)	6500 (SKP1)	55832 (CAND1)	8533 (COPS3)	6923 (TCEB2)	140739 (UBE2F)	9616 (RNF7)	9978 (RBX1)	55208 (DCUN1D2)	26259 (FBXW8)	9820 (CUL7)	123879 (DCUN1D3)	84259 (DCUN1D5)	51138 (COPS4)	8651 (SOCS1)	1154 (CISH)	9306 (SOCS6)	7321 (UBE2D1)	7428 (VHL)	26190 (FBXW2)	10116 (FEM1B)	9655 (SOCS5)	27338 (UBE2S)	26043 (UBXN7)	26272 (FBXO4)	122769 (LRR1)	51676 (ASB2)	7337 (UBE3A)	10444 (ZER1)	150684 (COMMD1)	56929 (FEM1C)	55527 (FEM1A)	997 (CDC34)	9817 (KEAP1)	79699 (ZYG11B)
54165 (DCUN1D1)	1.00	0.51	0.73	0.65	0.74	0.69	0.66	1.00	1.00	0.71	0.69	0.74	0.67	0.74	0.68	0.55	0.63	0.74	1.00	1.00	0.81	0.65	0.67	0.62	0.97	0.74	1.00	0.94	0.94	0.73	0.60	0.70	0.73	0.64	0.70	0.74	0.71	0.70	0.65	0.82	0.72	1.00	0.73	0.65	0.18	0.57	1.00	0.40	0.65	0.84	0.18
10987 (COPS5)	0.51	1.00	0.38	0.46	0.42	0.51	0.40	1.00	1.00	0.41	0.54	0.45	0.43	0.51	0.46	0.32	0.53	0.50	1.00	1.00	0.44	0.39	0.42	0.44	0.42	0.42	1.00	0.55	0.55	0.71	0.39	0.44	0.38	0.41	0.47	0.42	0.43	0.39	0.41	0.50	0.44	1.00	0.39	0.39	0.24	0.40	1.00	0.27	0.39	0.46	0.24
2873 (GPS1)	0.73	0.38	1.00	0.56	0.58	0.64	0.50	1.00	1.00	0.58	0.60	0.63	0.55	0.58	0.57	0.37	0.58	0.61	1.00	1.00	0.69	0.49	0.51	0.50	0.63	0.58	1.00	0.71	0.71	0.57	0.64	0.63	0.67	0.51	0.59	0.58	0.57	0.63	0.51	0.71	0.59	1.00	0.57	0.49	0.18	0.48	1.00	0.34	0.49	0.74	0.18
8452 (CUL3)	0.65	0.46	0.56	1.00	0.84	0.80	0.83	1.00	1.00	0.91	0.65	0.68	0.88	0.56	0.70	0.81	0.62	0.88	1.00	1.00	0.71	0.72	0.78	0.90	0.55	0.84	1.00	0.66	0.66	0.56	0.51	0.58	0.56	0.89	0.89	0.84	0.81	0.55	0.81	0.72	0.82	1.00	0.84	0.89	1.00	0.50	1.00	0.63	0.84	0.64	1.00
6921 (TCEB1)	0.74	0.42	0.58	0.84	1.00	0.76	0.94	1.00	1.00	0.83	0.61	0.64	0.93	0.59	0.74	0.85	0.58	0.90	1.00	1.00	0.70	0.79	0.77	0.84	0.64	1.00	1.00	0.72	0.72	0.59	0.49	0.59	0.59	0.90	0.91	1.00	0.91	0.57	0.90	0.72	0.92	1.00	0.89	0.95	1.00	0.49	1.00	0.77	0.95	0.75	1.00
55294 (FBXW7)	0.69	0.51	0.64	0.80	0.76	1.00	0.76	1.00	1.00	0.78	0.68	0.70	0.80	0.61	0.71	0.67	0.63	0.77	1.00	1.00	0.73	0.70	0.70	0.80	0.59	0.76	1.00	0.70	0.70	0.62	0.60	0.64	0.65	0.81	0.78	0.76	0.74	0.63	0.75	0.78	0.76	1.00	0.72	0.76	1.00	0.57	1.00	0.49	0.76	0.67	1.00
9040 (UBE2M)	0.66	0.40	0.50	0.83	0.94	0.76	1.00	1.00	1.00	0.78	0.56	0.57	0.90	0.51	0.81	0.83	0.56	0.88	1.00	1.00	0.59	0.91	0.83	0.88	0.56	0.94	1.00	0.67	0.67	0.51	0.46	0.55	0.50	0.87	0.89	0.94	0.87	0.50	0.87	0.64	0.89	1.00	0.82	0.91	1.00	0.46	1.00	0.76	0.91	0.64	1.00
10920 (COPS8)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.82	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.82	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.18	1.00	1.00	0.54	1.00	1.00	0.18
10980 (COPS6)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.82	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.82	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.18	1.00	1.00	0.54	1.00	1.00	0.18
8453 (CUL2)	0.71	0.41	0.58	0.91	0.83	0.78	0.78	1.00	1.00	1.00	0.70	0.75	0.88	0.59	0.67	0.83	0.62	0.87	1.00	1.00	0.83	0.68	0.78	0.89	0.61	0.83	1.00	0.69	0.69	0.58	0.50	0.58	0.58	0.88	0.89	0.83	0.78	0.57	0.77	0.81	0.79	1.00	0.92	0.90	0.77	0.49	1.00	0.58	0.79	0.71	0.77
7316 (UBC)	0.69	0.54	0.60	0.65	0.61	0.68	0.56	1.00	1.00	0.70	1.00	0.88	0.58	0.61	0.59	0.43	0.67	0.62	1.00	1.00	0.77	0.55	0.55	0.60	0.59	0.61	1.00	0.72	0.72	0.60	0.53	0.64	0.60	0.65	0.64	0.61	0.60	0.59	0.56	0.77	0.61	1.00	0.60	0.55	0.23	0.51	1.00	0.34	0.55	0.69	0.23
4738 (NEDD8)	0.74	0.45	0.63	0.68	0.64	0.70	0.57	1.00	1.00	0.75	0.88	1.00	0.60	0.64	0.61	0.42	0.65	0.64	1.00	1.00	0.87	0.56	0.56	0.62	0.64	0.64	1.00	0.77	0.77	0.62	0.53	0.68	0.63	0.68	0.64	0.64	0.62	0.61	0.57	0.84	0.63	1.00	0.62	0.56	0.23	0.51	1.00	0.37	0.56	0.75	0.23
6502 (SKP2)	0.67	0.43	0.55	0.88	0.93	0.80	0.90	1.00	1.00	0.88	0.58	0.60	1.00	0.55	0.76	0.90	0.57	0.93	1.00	1.00	0.62	0.76	0.83	0.89	0.57	0.93	1.00	0.68	0.68	0.55	0.49	0.57	0.55	0.87	0.94	0.93	0.88	0.54	0.87	0.66	0.91	1.00	0.93	0.97	1.00	0.52	1.00	0.71	0.91	0.66	1.00
9318 (COPS2)	0.74	0.51	0.58	0.56	0.59	0.61	0.51	1.00	1.00	0.59	0.61	0.64	0.55	1.00	0.58	0.37	0.58	0.62	1.00	1.00	0.70	0.50	0.52	0.50	0.64	0.59	1.00	0.72	0.72	0.58	0.49	0.59	0.59	0.52	0.59	0.59	0.58	0.57	0.52	0.72	0.59	1.00	0.58	0.50	0.18	0.49	1.00	0.35	0.50	0.75	0.18
9039 (UBA3)	0.68	0.46	0.57	0.70	0.74	0.71	0.81	1.00	1.00	0.67	0.59	0.61	0.76	0.58	1.00	0.61	0.61	0.74	1.00	1.00	0.64	0.81	0.74	0.75	0.57	0.74	1.00	0.68	0.68	0.58	0.51	0.59	0.57	0.70	0.73	0.74	0.71	0.56	0.70	0.66	0.74	1.00	0.68	0.71	0.70	0.54	1.00	0.50	0.71	0.67	0.70
51529 (ANAPC11)	0.55	0.32	0.37	0.81	0.85	0.67	0.83	0.82	0.82	0.83	0.43	0.42	0.90	0.37	0.61	1.00	0.44	0.90	0.82	0.82	0.43	0.66	0.83	0.89	0.50	0.85	0.82	0.57	0.57	0.38	0.35	0.42	0.37	0.79	0.87	0.85	0.79	0.37	0.80	0.47	0.80	0.82	0.88	0.93	1.00	0.36	0.82	0.72	0.84	0.46	1.00
3091 (HIF1A)	0.63	0.53	0.58	0.62	0.58	0.63	0.56	1.00	1.00	0.62	0.67	0.65	0.57	0.58	0.61	0.44	1.00	0.61	1.00	1.00	0.65	0.56	0.56	0.60	0.53	0.58	1.00	0.66	0.66	0.58	0.58	0.61	0.58	0.60	0.64	0.58	0.58	0.60	0.56	0.68	0.59	1.00	0.58	0.56	0.18	0.54	1.00	0.32	0.56	0.64	0.18
6500 (SKP1)	0.74	0.50	0.61	0.88	0.90	0.77	0.88	1.00	1.00	0.87	0.62	0.64	0.93	0.62	0.74	0.90	0.61	1.00	1.00	1.00	0.67	0.77	0.86	0.90	0.65	0.90	1.00	0.74	0.74	0.62	0.54	0.63	0.62	0.86	0.92	0.90	0.86	0.60	0.86	0.69	0.87	1.00	0.90	0.94	1.00	0.53	1.00	0.64	0.89	0.70	1.00
55832 (CAND1)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.82	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.82	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.18	1.00	1.00	0.54	1.00	1.00	0.18
8533 (COPS3)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.82	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.82	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.18	1.00	1.00	0.54	1.00	1.00	0.18
6923 (TCEB2)	0.81	0.44	0.69	0.71	0.70	0.73	0.59	1.00	1.00	0.83	0.77	0.87	0.62	0.70	0.64	0.43	0.65	0.67	1.00	1.00	1.00	0.59	0.58	0.63	0.71	0.70	1.00	0.76	0.76	0.68	0.54	0.65	0.69	0.72	0.67	0.70	0.66	0.65	0.59	0.92	0.68	1.00	0.69	0.59	0.18	0.52	1.00	0.39	0.59	0.85	0.18
140739 (UBE2F)	0.65	0.39	0.49	0.72	0.79	0.70	0.91	1.00	1.00	0.68	0.55	0.56	0.76	0.50	0.81	0.66	0.56	0.77	1.00	1.00	0.59	1.00	0.81	0.79	0.55	0.79	1.00	0.66	0.66	0.50	0.45	0.53	0.50	0.74	0.77	0.79	0.75	0.50	0.75	0.63	0.76	1.00	0.70	0.75	0.70	0.46	1.00	0.61	0.77	0.63	0.70
9616 (RNF7)	0.67	0.42	0.51	0.78	0.77	0.70	0.83	1.00	1.00	0.78	0.55	0.56	0.83	0.52	0.74	0.83	0.56	0.86	1.00	1.00	0.58	0.81	1.00	0.88	0.59	0.77	1.00	0.68	0.68	0.52	0.47	0.54	0.52	0.73	0.82	0.77	0.74	0.51	0.73	0.62	0.75	1.00	0.81	0.83	0.77	0.57	1.00	0.56	0.75	0.61	0.77
9978 (RBX1)	0.62	0.44	0.50	0.90	0.84	0.80	0.88	1.00	1.00	0.89	0.60	0.62	0.89	0.50	0.75	0.89	0.60	0.90	1.00	1.00	0.63	0.79	0.88	1.00	0.54	0.84	1.00	0.65	0.65	0.51	0.47	0.54	0.50	0.88	0.92	0.84	0.81	0.50	0.82	0.68	0.82	1.00	0.84	0.89	1.00	0.47	1.00	0.64	0.83	0.61	1.00
55208 (DCUN1D2)	0.97	0.42	0.63	0.55	0.64	0.59	0.56	0.82	0.82	0.61	0.59	0.64	0.57	0.64	0.57	0.50	0.53	0.65	0.82	0.82	0.71	0.55	0.59	0.54	1.00	0.64	0.82	0.90	0.90	0.63	0.50	0.59	0.64	0.55	0.60	0.64	0.60	0.60	0.54	0.73	0.61	0.82	0.63	0.55	0.15	0.47	0.82	0.35	0.55	0.74	0.15
26259 (FBXW8)	0.74	0.42	0.58	0.84	1.00	0.76	0.94	1.00	1.00	0.83	0.61	0.64	0.93	0.59	0.74	0.85	0.58	0.90	1.00	1.00	0.70	0.79	0.77	0.84	0.64	1.00	1.00	0.72	0.72	0.59	0.49	0.59	0.59	0.90	0.91	1.00	0.91	0.57	0.90	0.72	0.92	1.00	0.89	0.95	1.00	0.49	1.00	0.77	0.95	0.75	1.00
9820 (CUL7)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.82	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.82	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.18	1.00	1.00	0.54	1.00	1.00	0.18
123879 (DCUN1D3)	0.94	0.55	0.71	0.66	0.72	0.70	0.67	1.00	1.00	0.69	0.72	0.77	0.68	0.72	0.68	0.57	0.66	0.74	1.00	1.00	0.76	0.66	0.68	0.65	0.90	0.72	1.00	1.00	1.00	0.71	0.62	0.81	0.71	0.65	0.70	0.72	0.70	0.69	0.66	0.78	0.71	1.00	0.71	0.66	0.32	0.56	1.00	0.41	0.66	0.79	0.32
84259 (DCUN1D5)	0.94	0.55	0.71	0.66	0.72	0.70	0.67	1.00	1.00	0.69	0.72	0.77	0.68	0.72	0.68	0.57	0.66	0.74	1.00	1.00	0.76	0.66	0.68	0.65	0.90	0.72	1.00	1.00	1.00	0.71	0.62	0.81	0.71	0.65	0.70	0.72	0.70	0.69	0.66	0.78	0.71	1.00	0.71	0.66	0.32	0.56	1.00	0.41	0.66	0.79	0.32
51138 (COPS4)	0.73	0.71	0.57	0.56	0.59	0.62	0.51	1.00	1.00	0.58	0.60	0.62	0.55	0.58	0.58	0.38	0.58	0.62	1.00	1.00	0.68	0.50	0.52	0.51	0.63	0.59	1.00	0.71	0.71	1.00	0.48	0.57	0.57	0.52	0.59	0.59	0.58	0.56	0.52	0.71	0.60	1.00	0.57	0.50	0.19	0.48	1.00	0.36	0.50	0.74	0.19
8651 (SOCS1)	0.60	0.39	0.64	0.51	0.49	0.60	0.46	1.00	1.00	0.50	0.53	0.53	0.49	0.49	0.51	0.35	0.58	0.54	1.00	1.00	0.54	0.45	0.47	0.47	0.50	0.49	1.00	0.62	0.62	0.48	1.00	0.75	0.78	0.47	0.53	0.49	0.50	0.79	0.47	0.58	0.50	1.00	0.49	0.45	0.18	0.46	1.00	0.30	0.45	0.57	0.18
1154 (CISH)	0.70	0.44	0.63	0.58	0.59	0.64	0.55	1.00	1.00	0.58	0.64	0.68	0.57	0.59	0.59	0.42	0.61	0.63	1.00	1.00	0.65	0.53	0.54	0.54	0.59	0.59	1.00	0.81	0.81	0.57	0.75	1.00	0.90	0.54	0.60	0.59	0.58	0.83	0.55	0.68	0.59	1.00	0.58	0.53	0.32	0.48	1.00	0.37	0.53	0.69	0.32
9306 (SOCS6)	0.73	0.38	0.67	0.56	0.59	0.65	0.50	1.00	1.00	0.58	0.60	0.63	0.55	0.59	0.57	0.37	0.58	0.62	1.00	1.00	0.69	0.50	0.52	0.50	0.64	0.59	1.00	0.71	0.71	0.57	0.78	0.90	1.00	0.51	0.59	0.59	0.58	0.90	0.52	0.71	0.59	1.00	0.57	0.50	0.18	0.48	1.00	0.34	0.50	0.74	0.18
7321 (UBE2D1)	0.64	0.41	0.51	0.89	0.90	0.81	0.87	1.00	1.00	0.88	0.65	0.68	0.87	0.52	0.70	0.79	0.60	0.86	1.00	1.00	0.72	0.74	0.73	0.88	0.55	0.90	1.00	0.65	0.65	0.52	0.47	0.54	0.51	1.00	0.88	0.90	0.84	0.51	0.90	0.73	0.85	1.00	0.79	0.88	1.00	0.47	1.00	0.69	0.94	0.62	1.00
7428 (VHL)	0.70	0.47	0.59	0.89	0.91	0.78	0.89	1.00	1.00	0.89	0.64	0.64	0.94	0.59	0.73	0.87	0.64	0.92	1.00	1.00	0.67	0.77	0.82	0.92	0.60	0.91	1.00	0.70	0.70	0.59	0.53	0.60	0.59	0.88	1.00	0.91	0.87	0.59	0.87	0.73	0.88	1.00	0.91	0.95	1.00	0.51	1.00	0.67	0.90	0.73	1.00
26190 (FBXW2)	0.74	0.42	0.58	0.84	1.00	0.76	0.94	1.00	1.00	0.83	0.61	0.64	0.93	0.59	0.74	0.85	0.58	0.90	1.00	1.00	0.70	0.79	0.77	0.84	0.64	1.00	1.00	0.72	0.72	0.59	0.49	0.59	0.59	0.90	0.91	1.00	0.91	0.57	0.90	0.72	0.92	1.00	0.89	0.95	1.00	0.49	1.00	0.77	0.95	0.75	1.00
10116 (FEM1B)	0.71	0.43	0.57	0.81	0.91	0.74	0.87	1.00	1.00	0.78	0.60	0.62	0.88	0.58	0.71	0.79	0.58	0.86	1.00	1.00	0.66	0.75	0.74	0.81	0.60	0.91	1.00	0.70	0.70	0.58	0.50	0.58	0.58	0.84	0.87	0.91	1.00	0.56	0.85	0.69	0.86	1.00	0.82	0.89	1.00	0.49	1.00	0.69	0.89	0.71	1.00
9655 (SOCS5)	0.70	0.39	0.63	0.55	0.57	0.63	0.50	1.00	1.00	0.57	0.59	0.61	0.54	0.57	0.56	0.37	0.60	0.60	1.00	1.00	0.65	0.50	0.51	0.50	0.60	0.57	1.00	0.69	0.69	0.56	0.79	0.83	0.90	0.51	0.59	0.57	0.56	1.00	0.51	0.68	0.57	1.00	0.56	0.50	0.18	0.48	1.00	0.35	0.50	0.69	0.18
27338 (UBE2S)	0.65	0.41	0.51	0.81	0.90	0.75	0.87	1.00	1.00	0.77	0.56	0.57	0.87	0.52	0.70	0.80	0.56	0.86	1.00	1.00	0.59	0.75	0.73	0.82	0.54	0.90	1.00	0.66	0.66	0.52	0.47	0.55	0.52	0.90	0.87	0.90	0.85	0.51	1.00	0.63	0.86	1.00	0.79	0.88	1.00	0.47	1.00	0.70	0.95	0.63	1.00
26043 (UBXN7)	0.82	0.50	0.71	0.72	0.72	0.78	0.64	1.00	1.00	0.81	0.77	0.84	0.66	0.72	0.66	0.47	0.68	0.69	1.00	1.00	0.92	0.63	0.62	0.68	0.73	0.72	1.00	0.78	0.78	0.71	0.58	0.68	0.71	0.73	0.73	0.72	0.69	0.68	0.63	1.00	0.70	1.00	0.71	0.63	0.18	0.56	1.00	0.39	0.63	0.88	0.18
26272 (FBXO4)	0.72	0.44	0.59	0.82	0.92	0.76	0.89	1.00	1.00	0.79	0.61	0.63	0.91	0.59	0.74	0.80	0.59	0.87	1.00	1.00	0.68	0.76	0.75	0.82	0.61	0.92	1.00	0.71	0.71	0.60	0.50	0.59	0.59	0.85	0.88	0.92	0.86	0.57	0.86	0.70	1.00	1.00	0.83	0.90	1.00	0.56	1.00	0.68	0.90	0.72	1.00
122769 (LRR1)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.82	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.82	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.18	1.00	1.00	0.54	1.00	1.00	0.18
51676 (ASB2)	0.73	0.39	0.57	0.84	0.89	0.72	0.82	1.00	1.00	0.92	0.60	0.62	0.93	0.58	0.68	0.88	0.58	0.90	1.00	1.00	0.69	0.70	0.81	0.84	0.63	0.89	1.00	0.71	0.71	0.57	0.49	0.58	0.57	0.79	0.91	0.89	0.82	0.56	0.79	0.71	0.83	1.00	1.00	0.95	0.77	0.48	1.00	0.66	0.83	0.74	0.77
7337 (UBE3A)	0.65	0.39	0.49	0.89	0.95	0.76	0.91	1.00	1.00	0.90	0.55	0.56	0.97	0.50	0.71	0.93	0.56	0.94	1.00	1.00	0.59	0.75	0.83	0.89	0.55	0.95	1.00	0.66	0.66	0.50	0.45	0.53	0.50	0.88	0.95	0.95	0.89	0.50	0.88	0.63	0.90	1.00	0.95	1.00	1.00	0.46	1.00	0.77	0.92	0.63	1.00
10444 (ZER1)	0.18	0.24	0.18	1.00	1.00	1.00	1.00	0.18	0.18	0.77	0.23	0.23	1.00	0.18	0.70	1.00	0.18	1.00	0.18	0.18	0.18	0.70	0.77	1.00	0.15	1.00	0.18	0.32	0.32	0.19	0.18	0.32	0.18	1.00	1.00	1.00	1.00	0.18	1.00	0.18	1.00	0.18	0.77	1.00	1.00	0.18	0.18	1.00	1.00	0.18	1.00
150684 (COMMD1)	0.57	0.40	0.48	0.50	0.49	0.57	0.46	1.00	1.00	0.49	0.51	0.51	0.52	0.49	0.54	0.36	0.54	0.53	1.00	1.00	0.52	0.46	0.57	0.47	0.47	0.49	1.00	0.56	0.56	0.48	0.46	0.48	0.48	0.47	0.51	0.49	0.49	0.48	0.47	0.56	0.56	1.00	0.48	0.46	0.18	1.00	1.00	0.26	0.46	0.54	0.18
56929 (FEM1C)	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.82	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.82	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.18	1.00	1.00	0.54	1.00	1.00	0.18
55527 (FEM1A)	0.40	0.27	0.34	0.63	0.77	0.49	0.76	0.54	0.54	0.58	0.34	0.37	0.71	0.35	0.50	0.72	0.32	0.64	0.54	0.54	0.39	0.61	0.56	0.64	0.35	0.77	0.54	0.41	0.41	0.36	0.30	0.37	0.34	0.69	0.67	0.77	0.69	0.35	0.70	0.39	0.68	0.54	0.66	0.77	1.00	0.26	0.54	1.00	0.77	0.42	1.00
997 (CDC34)	0.65	0.39	0.49	0.84	0.95	0.76	0.91	1.00	1.00	0.79	0.55	0.56	0.91	0.50	0.71	0.84	0.56	0.89	1.00	1.00	0.59	0.77	0.75	0.83	0.55	0.95	1.00	0.66	0.66	0.50	0.45	0.53	0.50	0.94	0.90	0.95	0.89	0.50	0.95	0.63	0.90	1.00	0.83	0.92	1.00	0.46	1.00	0.77	1.00	0.63	1.00
9817 (KEAP1)	0.84	0.46	0.74	0.64	0.75	0.67	0.64	1.00	1.00	0.71	0.69	0.75	0.66	0.75	0.67	0.46	0.64	0.70	1.00	1.00	0.85	0.63	0.61	0.61	0.74	0.75	1.00	0.79	0.79	0.74	0.57	0.69	0.74	0.62	0.73	0.75	0.71	0.69	0.63	0.88	0.72	1.00	0.74	0.63	0.18	0.54	1.00	0.42	0.63	1.00	0.18
79699 (ZYG11B)	0.18	0.24	0.18	1.00	1.00	1.00	1.00	0.18	0.18	0.77	0.23	0.23	1.00	0.18	0.70	1.00	0.18	1.00	0.18	0.18	0.18	0.70	0.77	1.00	0.15	1.00	0.18	0.32	0.32	0.19	0.18	0.32	0.18	1.00	1.00	1.00	1.00	0.18	1.00	0.18	1.00	0.18	0.77	1.00	1.00	0.18	0.18	1.00	1.00	0.18	1.00

Association with High Altitude

Protein Official symbol	Source Organism	Tissue of Expression	Level of hypoxia	Altitude	Duration of experiment	Level of expression	Fold change	Experiment details	geographical location	ethnicity of the patients	Control group	Control (Fold change)	Reference (PMID)
CUL2	Human	Blood	-	3650 m	48 hours	downregulated	0.646	Microarray	Himalayas	Indians	1	HAPE Pateints Vs Normal	http://medind.nic.in/iab/t12/i1/iabt12i1p1.pdf

Association with TF

TF	TF Entrez	Gene	Gene Entrez	Type	PMID	Database
CEBPB	1051	CUL2	8453	proximal_filtered	22955619	TRANSFAC

Association with miRNA

miRTarBase ID	miRNA	Species (miRNA)	Protein Official Symbol	Human Entrez ID	Species (Target Gene)	Experiments	Support Type	References (PMID)
MIRT005927	hsa-miR-424-5p	Homo sapiens	CUL2	8453	Homo sapiens	ChIP-seq//Luciferase reporter assay//Microarray//qRT-PCR//Western blot	Functional MTI	20972335
MIRT007130	hsa-miR-30c-5p	Homo sapiens	CUL2	8453	Homo sapiens	qRT-PCR	Functional MTI (Weak)	23418453
MIRT038756	hsa-miR-93-3p	Homo sapiens	CUL2	8453	Homo sapiens	CLASH	Functional MTI (Weak)	23622248
MIRT048406	hsa-miR-100-5p	Homo sapiens	CUL2	8453	Homo sapiens	CLASH	Functional MTI (Weak)	23622248
MIRT048623	hsa-miR-99a-5p	Homo sapiens	CUL2	8453	Homo sapiens	CLASH	Functional MTI (Weak)	23622248
MIRT052315	hsa-let-7b-5p	Homo sapiens	CUL2	8453	Homo sapiens	CLASH	Functional MTI (Weak)	23622248
MIRT052839	hsa-miR-4326	Homo sapiens	CUL2	8453	Homo sapiens	CLASH	Functional MTI (Weak)	23622248
MIRT053490	hsa-miR-574-3p	Homo sapiens	CUL2	8453	Homo sapiens	Microarray//qRT-PCR//Western blot	Functional MTI	22683180
MIRT126912	hsa-miR-3163	Homo sapiens	CUL2	8453	Homo sapiens	PAR-CLIP//HITS-CLIP	Functional MTI (Weak)	21572407
MIRT126912	hsa-miR-3163	Homo sapiens	CUL2	8453	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT126912	hsa-miR-3163	Homo sapiens	CUL2	8453	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT126912	hsa-miR-3163	Homo sapiens	CUL2	8453	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT126912	hsa-miR-3163	Homo sapiens	CUL2	8453	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT509019	hsa-miR-410-3p	Homo sapiens	CUL2	8453	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT509019	hsa-miR-410-3p	Homo sapiens	CUL2	8453	Homo sapiens	PAR-CLIP//HITS-CLIP	Functional MTI (Weak)	21572407
MIRT509016	hsa-miR-190a-3p	Homo sapiens	CUL2	8453	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT509015	hsa-miR-1277-5p	Homo sapiens	CUL2	8453	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT509017	hsa-miR-656-3p	Homo sapiens	CUL2	8453	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT509018	hsa-miR-5011-5p	Homo sapiens	CUL2	8453	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT509017	hsa-miR-656-3p	Homo sapiens	CUL2	8453	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT509016	hsa-miR-190a-3p	Homo sapiens	CUL2	8453	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT509015	hsa-miR-1277-5p	Homo sapiens	CUL2	8453	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT509019	hsa-miR-410-3p	Homo sapiens	CUL2	8453	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT509015	hsa-miR-1277-5p	Homo sapiens	CUL2	8453	Homo sapiens	PAR-CLIP//HITS-CLIP	Functional MTI (Weak)	21572407
MIRT509017	hsa-miR-656-3p	Homo sapiens	CUL2	8453	Homo sapiens	PAR-CLIP//HITS-CLIP	Functional MTI (Weak)	21572407
MIRT509018	hsa-miR-5011-5p	Homo sapiens	CUL2	8453	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT509015	hsa-miR-1277-5p	Homo sapiens	CUL2	8453	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT509016	hsa-miR-190a-3p	Homo sapiens	CUL2	8453	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT509018	hsa-miR-5011-5p	Homo sapiens	CUL2	8453	Homo sapiens	PAR-CLIP//HITS-CLIP	Functional MTI (Weak)	21572407
MIRT509016	hsa-miR-190a-3p	Homo sapiens	CUL2	8453	Homo sapiens	PAR-CLIP//HITS-CLIP	Functional MTI (Weak)	21572407
MIRT509015	hsa-miR-1277-5p	Homo sapiens	CUL2	8453	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT509018	hsa-miR-5011-5p	Homo sapiens	CUL2	8453	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT509019	hsa-miR-410-3p	Homo sapiens	CUL2	8453	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	23446348
MIRT509019	hsa-miR-410-3p	Homo sapiens	CUL2	8453	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	23313552
MIRT509017	hsa-miR-656-3p	Homo sapiens	CUL2	8453	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	20371350
MIRT558513	hsa-miR-1267	Homo sapiens	CUL2	8453	Homo sapiens	PAR-CLIP//HITS-CLIP	Functional MTI (Weak)	21572407
MIRT727914	hsa-miR-195-5p	Homo sapiens	CUL2	8453	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	22473208
MIRT727915	hsa-miR-16-5p	Homo sapiens	CUL2	8453	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	22473208
MIRT727916	hsa-miR-15b-5p	Homo sapiens	CUL2	8453	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	22473208
MIRT727917	hsa-miR-15a-5p	Homo sapiens	CUL2	8453	Homo sapiens	HITS-CLIP	Functional MTI (Weak)	22473208
MIRT733836	hsa-miR-195-3p	Homo sapiens	CUL2	8453	Homo sapiens	Microarray//qRT-PCR	Functional MTI (Weak)	27144577

Gene Ontology

ID	GO ID	GO Term	GO Type
8453	GO:0007050	cell cycle arrest	GOTERM_BP_DIRECT
8453	GO:0006511	ubiquitin-dependent protein catabolic process	GOTERM_BP_DIRECT
8453	GO:0000082	G1/S transition of mitotic cell cycle	GOTERM_BP_DIRECT
8453	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	GOTERM_BP_DIRECT
8453	GO:0008285	negative regulation of cell proliferation	GOTERM_BP_DIRECT
8453	GO:0016032	viral process	GOTERM_BP_DIRECT
8453	GO:0005829	cytosol	GOTERM_CC_DIRECT
8453	GO:0005730	nucleolus	GOTERM_CC_DIRECT
8453	GO:0005515	protein binding	GOTERM_MF_DIRECT
8453	GO:0005654	nucleoplasm	GOTERM_CC_DIRECT
8453	GO:0097193	intrinsic apoptotic signaling pathway	GOTERM_BP_DIRECT
8453	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	GOTERM_BP_DIRECT
8453	GO:0061630	glycogen synthase activity	GOTERM_MF_DIRECT
8453	GO:0031461	cullin-RING ubiquitin ligase complex	GOTERM_CC_DIRECT
8453	GO:0031462	Cul2-RING ubiquitin ligase complex	GOTERM_CC_DIRECT
8453	GO:0032403	protein complex binding	GOTERM_MF_DIRECT
8453	GO:0031625	ubiquitin protein ligase binding	GOTERM_MF_DIRECT
8453	GO:0030891	VCB complex	GOTERM_CC_DIRECT

Pathways

Human Entrez ID	KEGG ID	KEGG Term
8453	hsa04066	HIF-1 signaling pathway
8453	hsa04120	Ubiquitin mediated proteolysis
8453	hsa05200	Pathways in cancer
8453	hsa05211	Renal cell carcinoma

Association with Disease

Protein Official Symbol	Human Entrez ID	Disease Name	Disease Id	Disease Semantic Type	Semantic score	DSI	DPI	Disease Type
CUL2	8453	Inflammatory Bowel Diseases	C0021390	Disease or Syndrome	0.3	0.743	0.31	group

Association with Drug

Protein Official Symbol	Human Entrez ID	drug_claim_primary_name	drug_name	drug_chembl_id	interaction_types