ALTITUDEOMICSDB

CCN family member 1

AltitudeomicsDB

Protein Official symbol	CYR61
Aliases	CCN1 CYR61 GIG1 IGFBP10
Chromosomal Location	3
Length	381
Uniprot ID	O00622
EC number	None
Protein family Information(Pfam)	PF00007;PF00219;PF00093;
PDB id	4D0Z;4D11;
InterPro ID	IPR006207;IPR006208;IPR009030;IPR000867;IPR012395;IPR017891;IPR000884;IPR036383;IPR001007;
dbSNP	rs9658587

Protein Protein Interaction

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AltitudeomicsDB

Protein 1	Protein 2	Combine Score
P4HB	HSP90B1	0.998
FN1	ITGAV	0.995
APP	APOE	0.995
LAMC1	LAMB1	0.992
ITGAM	ITGB2	0.992
CALU	P4HB	0.991
FN1	ALB	0.99
IGFBP1	IGFBP4	0.989
FN1	FBN1	0.989
FN1	PCSK9	0.988
APP	ADAM10	0.988
ITGB5	ITGAV	0.988
LAMB2	LAMC1	0.985
P4HB	RCN1	0.985
IGFBP3	FN1	0.984
HSP90B1	RCN1	0.983
IL6	ALB	0.983
FBN1	VCAN	0.983
IL6	TIMP1	0.982
FN1	IGFBP5	0.982
FN1	CDH2	0.981
FN1	SDC2	0.981
CYR61	IGFBP7	0.98
ALB	APOE	0.979
SPP1	TIMP1	0.978
IL6	SPP1	0.978
CST3	ALB	0.978
SPP1	ALB	0.978
SPP1	FN1	0.977
IL6	CSF1	0.976
SPP1	FAM20C	0.975
GAS6	MFGE8	0.975
LTBP1	FN1	0.974
FN1	TIMP1	0.972
CDH2	ADAM10	0.972
ITGB2	ITGAV	0.971
SPP1	ITGAV	0.971
IL6	FN1	0.971
IL6	FSTL1	0.97
FN1	VCAN	0.97
IL6	APOE	0.969
IL6	IGFBP1	0.969
ALB	IGFBP1	0.969
FSTL1	FSTL3	0.967
ADAM10	TIMP1	0.967
IGFBP3	IGFBP7	0.966
CDH2	BMP4	0.966
PCSK9	APOE	0.966
APP	CDH2	0.966
IGFBP7	IGFBP5	0.965
GPC3	SDC2	0.965
ALB	APP	0.965
FN1	TNC	0.964
CALU	HSP90B1	0.964
IGFBP7	IGFBP4	0.962
FN1	BMP4	0.962
IL6	HSP90B1	0.961
FN1	LAMB1	0.961
SPARCL1	SPP1	0.961
CDH2	VCAN	0.96
CST3	APOE	0.959
FBN1	FSTL1	0.958
CYR61	FN1	0.958
SPP1	MSLN	0.957
IL6	APP	0.957
ALB	CDH2	0.956
IGFBP7	IGFBP1	0.956
IL6	CST3	0.956
ALB	TIMP1	0.956
CST3	APP	0.956
ALB	BMP4	0.955
P4HB	ALB	0.955
SPP1	IGFBP5	0.955
LTBP1	FBN1	0.954
SPP1	BMP4	0.954
CST3	IGFBP7	0.954
IL6	IGFBP3	0.953
CST3	TIMP1	0.953
GPC3	BMP4	0.953
CST3	SPP1	0.953
IGFBP3	SDC2	0.953
FN1	APOE	0.952
FSTL1	BMP4	0.952
CSF1	ALB	0.952
LTBP1	IGFBP3	0.952
FN1	LAMC1	0.952
CYR61	ITGB5	0.95
MFGE8	ITGAV	0.95
LTBP1	IGFBP5	0.95
ADAM10	APOE	0.95
IGFBP1	TIMP1	0.95
SPP1	CSF1	0.95
IGFBP3	TIMP1	0.949
CYR61	ITGAV	0.949
SPP1	APOE	0.949
FN1	CSF1	0.948
CYR61	IGFBP3	0.948
IGFBP3	ALB	0.948
VCAN	BMP4	0.948
GPC3	ALB	0.948
SPP1	CDH2	0.947
FN1	FSTL3	0.947
FN1	GAS6	0.946
FN1	APP	0.946
CSF1	TIMP1	0.946
VCAN	TIMP1	0.946
CALU	ALB	0.945
ITGAV	LAMC1	0.945
FAM20C	IGFBP1	0.945
FAM20C	STC2	0.945
IL6	BMP4	0.945
IL6	CDH2	0.945
FN1	IGFBP1	0.945
SPP1	ITGB5	0.945
APOE	TIMP1	0.944
FN1	FSTL1	0.944
SPARCL1	GPC3	0.943
FN1	ADAM10	0.943
BMP4	FSTL3	0.943
IGFBP4	STC2	0.943
HSP90B1	ALB	0.943
CALU	PCSK9	0.943
MATN3	FN1	0.942
SPP1	VCAN	0.942
FBN1	BMP4	0.942
FN1	FAM20C	0.942
IL6	ADAM10	0.941
PCSK9	HSP90B1	0.941
FAM20C	PCSK9	0.941
TNC	BMP4	0.941
IGFBP3	FAM20C	0.94
IL6	VCAN	0.94
GPC3	VCAN	0.94
CYR61	IL6	0.94
IL6	GAS6	0.939
CDH2	TIMP1	0.939
CSF1	APOE	0.939
SDC2	VCAN	0.939
FBN1	TIMP1	0.939
FN1	P4HB	0.939
FN1	IGFBP7	0.938
PCSK9	ALB	0.938
SPP1	GPC3	0.938
MXRA8	APP	0.938
GPC3	IGFBP1	0.938
CALU	FN1	0.937
ITGAV	LAMB1	0.937
GAS6	ALB	0.937
FAM20C	IGFBP5	0.937
CYR61	IGFBP5	0.937
FN1	IGFBP4	0.937
TNC	LAMC1	0.936
FBN1	LAMC1	0.936
IGFBP3	IGFBP1	0.936
CYR61	GAS6	0.936
SPARCL1	FSTL1	0.936
CYR61	BMP4	0.936
FBN1	LAMB1	0.936
FN1	LGALS1	0.936
IL6	FAM20C	0.935
TIMP1	LGALS1	0.935
ALB	VCAN	0.935
IGFBP7	TIMP1	0.935
IL6	MFGE8	0.935
SPP1	IGFBP3	0.935
GPC3	FN1	0.934
FN1	HSP90B1	0.934
CYR61	TIMP1	0.934
IL6	IGFBP7	0.934
CYR61	FSTL1	0.934
IGFBP4	TIMP1	0.934
CST3	FN1	0.934
LTBP1	VCAN	0.934
IGFBP1	VCAN	0.933
CKAP4	P4HB	0.933
LTBP1	FSTL1	0.933
GAS6	CSF1	0.933
SPARCL1	FN1	0.933
CALU	FAM20C	0.933
ALB	ADAM10	0.933
CSF1	ITGAV	0.933
LAMB2	FN1	0.933
CYR61	LAMB1	0.933
P4HB	APP	0.932
VWA1	ALB	0.932
FSTL1	LAMC1	0.932
SPP1	IGFBP1	0.932
IL6	MSLN	0.932
IGFBP3	STC2	0.932
FN1	MFGE8	0.932
IGFBP3	IGFBP4	0.931
HSP90B1	APP	0.931
MSLN	ALB	0.931
CYR61	SPP1	0.931
FN1	PRSS23	0.931
VWA1	FN1	0.931
IGFBP4	VCAN	0.931
ITGAV	ADAM10	0.931
STC2	IGFBP5	0.931
CALU	IL6	0.93
FBN1	ADAM10	0.93
LTBP1	TIMP1	0.93
FBN1	SDC2	0.93
SPARCL1	FAM20C	0.93
FBN1	APP	0.93
ALB	TNC	0.93
IL6	IGFBP5	0.93
LAMC1	LGALS1	0.93
IGFBP5	TIMP1	0.93
IGFBP7	BMP4	0.929
ITGAM	ADAM10	0.929
FAM20C	APP	0.929
CST3	FAM20C	0.929
FBN1	ITGAV	0.929
IL6	PCSK9	0.929
FSTL1	LAMB1	0.929
GPC3	MSLN	0.928
IL6	IGFBP4	0.928
LAMB2	FSTL1	0.928
CYR61	LAMB2	0.928
FBN1	APOE	0.928
MFGE8	APOE	0.928
SPP1	MFGE8	0.927
CKAP4	HSP90B1	0.927
IGFBP7	VCAN	0.927
SPARCL1	APOE	0.927
FBN1	ALB	0.927
CYR61	CDH2	0.927
CYR61	IGFBP4	0.927
IL6	GPC3	0.926
CSF1	BMP4	0.926
IL6	P4HB	0.926
ALB	MFGE8	0.926
SPP1	FBN1	0.926
APP	TIMP1	0.926
IGFBP3	BMP4	0.926
PCSK9	CDH2	0.926
LAMB1	TIMP1	0.926
CSF1	MFGE8	0.925
IGFBP3	CSF1	0.925
LTBP1	BMP4	0.925
FSTL1	IGFBP5	0.925
BMP4	IGFBP5	0.925
SPP1	IGFBP7	0.925
P4HB	ADAM10	0.925
ALB	IGFBP7	0.925
IGFBP1	STC2	0.925
CDH2	LAMB1	0.924
LTBP1	ALB	0.924
LAMC1	IGFBP5	0.924
FAM20C	VCAN	0.924
FAM20C	ALB	0.923
VWA1	APP	0.923
VWA1	MATN3	0.923
IL6	TNC	0.923
MATN3	HSP90B1	0.923
IGFBP3	FBN1	0.923
CSF1	APP	0.923
IGFBP7	FSTL1	0.923
MSLN	FN1	0.923
LAMB2	TNC	0.923
P4HB	APOE	0.923
SPP1	GAS6	0.923
IL6	FBN1	0.923
IGFBP1	FSTL3	0.923
IGFBP3	LAMB1	0.923
CYR61	FBN1	0.923
IGFBP3	CDH2	0.923
BMP4	TIMP1	0.923
VCAN	APOE	0.923
CDH2	TNC	0.922
LAMC1	TIMP1	0.922
HSP90B1	APOE	0.922
APP	MFGE8	0.922
IGFBP4	BMP4	0.922
P4HB	FBN1	0.922
CYR61	TNC	0.922
LTBP1	LAMC1	0.922
IGFBP7	FSTL3	0.922
ALB	IGFBP4	0.922
IGFBP3	IGFBP5	0.922
IGFBP3	FSTL3	0.922
IGFBP5	LAMB1	0.922
CSF1	VCAN	0.922
LAMB2	ALB	0.922
IL6	LGALS1	0.922
SPARCL1	FBN1	0.921
ITGAM	ITGAV	0.921
IGFBP1	LAMB1	0.921
SPP1	SDC2	0.921
CYR61	CSF1	0.921
SPARCL1	CYR61	0.921
VCAN	IGFBP5	0.921
PCSK9	IGFBP1	0.921
APP	TNC	0.921
LTBP1	FAM20C	0.921
TNC	LAMB1	0.921
ALB	IGFBP5	0.921
IGFBP3	FSTL1	0.921
CSF1	IGFBP4	0.921
CSF1	IGFBP1	0.921
GAS6	APOE	0.921
LTBP1	LAMB1	0.921
GPC3	CDH2	0.92
IGFBP4	APOE	0.92
IGFBP4	IGFBP5	0.92
IGFBP3	APOE	0.92
IGFBP3	PCSK9	0.92
CYR61	LAMC1	0.92
CYR61	VCAN	0.92
VWA1	RCN1	0.92
CYR61	IGFBP1	0.92
TNC	ITGAV	0.92
SDC2	LAMB1	0.92
LTBP1	CDH2	0.92
GAS6	IGFBP4	0.92
FSTL1	CDH2	0.92
LTBP1	IGFBP4	0.92
SDC2	CDH2	0.92
APOE	BMP4	0.92
IGFBP1	LGALS1	0.919
FAM20C	FSTL1	0.919
GAS6	BMP4	0.919
FSTL1	TNC	0.919
P4HB	PCSK9	0.919
CALU	FSTL1	0.919
MSLN	TIMP1	0.919
FAM20C	CDH2	0.919
FBN1	IGFBP7	0.919
CYR61	SDC2	0.919
CDH2	IGFBP5	0.919
PCSK9	APP	0.919
IGFBP4	LAMB1	0.919
GPC3	APOE	0.919
LTBP1	PRSS23	0.919
CALU	APOE	0.919
MXRA8	TNC	0.919
CYR61	ALB	0.919
CYR61	STC2	0.919
FBN1	IGFBP5	0.919
FSTL1	TIMP1	0.919
FSTL1	IGFBP4	0.919
CDH2	LAMC1	0.918
ALB	LAMB1	0.918
SDC2	TIMP1	0.918
FBN1	TNC	0.918
CYR61	EVA1A	0.918
STC2	FSTL3	0.918
GAS6	CDH2	0.918
IL6	FSTL3	0.918
IGFBP3	TNC	0.918
MSLN	CDH2	0.918
SDC2	APOE	0.918
LAMC1	BMP4	0.918
SPP1	APP	0.918
SPARCL1	IGFBP7	0.918
LAMB2	LAMB1	0.918
FN1	EVA1A	0.918
MXRA8	GAS6	0.918
LAMB2	IGFBP4	0.918
ALB	FSTL1	0.917
IGFBP3	VCAN	0.917
SPP1	LGALS1	0.917
CSF1	FSTL1	0.917
FN1	STC2	0.917
FBN1	CDH2	0.917
TNC	IGFBP5	0.917
CSF1	CDH2	0.917
VCAN	LAMC1	0.917
CYR61	LTBP1	0.917
IGFBP1	BMP4	0.917
FBN1	LGALS1	0.917
LAMB1	LGALS1	0.917
SPARCL1	APP	0.917
CALU	APP	0.917
CYR61	CST3	0.917
SPP1	IGFBP4	0.917
P4HB	TIMP1	0.916
STC2	RCN1	0.916
MSLN	CSF1	0.916
MATN3	BMP4	0.916
LAMB2	CSF1	0.916
MXRA8	FBN1	0.916
LTBP1	APP	0.916
LAMB2	IGFBP3	0.916
LAMB2	IGFBP5	0.916
IGFBP1	CDH2	0.916
FBN1	PRSS23	0.916
STC2	VCAN	0.916
ALB	LGALS1	0.916
GPC3	IGFBP3	0.916
CST3	IGFBP5	0.916
LTBP1	SDC2	0.916
VCAN	LGALS1	0.916
SPARCL1	BMP4	0.916
TIMP1	FSTL3	0.916
IGFBP1	IGFBP5	0.916
IGFBP7	PRSS23	0.916
CYR61	ITGB2	0.916
HSP90B1	MFGE8	0.915
STC2	LAMB1	0.915
ALB	LAMC1	0.915
GPC3	IGFBP5	0.915
VWA1	SPARCL1	0.915
FAM20C	FSTL3	0.915
IGFBP3	GAS6	0.915
TNC	VCAN	0.915
MATN3	VCAN	0.915
IGFBP1	APOE	0.915
IGFBP3	PRSS23	0.915
CALU	LAMC1	0.915
LTBP1	ADAM10	0.915
CSF1	PCSK9	0.915
APOE	LGALS1	0.915
CKAP4	FBN1	0.915
MXRA8	LAMB2	0.915
SPARCL1	ALB	0.915
STC2	LAMC1	0.915
CDH2	APOE	0.915
SDC2	BMP4	0.915
TNC	APOE	0.915
BMP4	LGALS1	0.915
SDC2	ALB	0.915
IGFBP3	LGALS1	0.915
LTBP1	MFGE8	0.915
SPARCL1	VCAN	0.915
IGFBP3	APP	0.915
APP	BMP4	0.915
VCAN	LAMB1	0.915
MXRA8	IGFBP5	0.914
SDC2	FSTL1	0.914
MATN3	PRSS23	0.914
IGFBP3	EVA1A	0.914
IGFBP7	LAMB1	0.914
MXRA8	FSTL1	0.914
CALU	TIMP1	0.914
FSTL1	VCAN	0.914
SPP1	P4HB	0.914
MATN3	P4HB	0.914
P4HB	LAMB1	0.914
MSLN	IGFBP1	0.914
SPARCL1	LAMB1	0.914
FN1	RCN1	0.914
VWA1	ADAM10	0.914
CST3	IGFBP3	0.914
MATN3	ADAM10	0.914
IGFBP4	LAMC1	0.914
APOE	EVA1A	0.914
CST3	FSTL3	0.914
GPC3	FBN1	0.914
APP	VCAN	0.914
MXRA8	IGFBP3	0.914
GPC3	TNC	0.914
BMP4	LAMB1	0.914
LTBP1	TNC	0.914
SPP1	STC2	0.913
SDC2	LAMC1	0.913
GAS6	APP	0.913
LTBP1	SPP1	0.913
GPC3	LAMB1	0.913
CALU	CDH2	0.913
GAS6	ADAM10	0.913
VWA1	BMP4	0.913
FSTL1	RCN1	0.913
LAMB1	RCN1	0.913
IGFBP7	MFGE8	0.913
SPP1	FSTL3	0.913
LAMB2	SDC2	0.913
GAS6	FAM20C	0.913
LAMB2	GAS6	0.913
MATN3	LAMC1	0.913
CALU	LTBP1	0.913
MXRA8	LTBP1	0.913
PRSS23	TNC	0.913
VWA1	LAMC1	0.913
GPC3	TIMP1	0.913
LAMB2	LTBP1	0.912
LAMB2	FSTL3	0.912
CYR61	MFGE8	0.912
CALU	CKAP4	0.912
CST3	GAS6	0.912
P4HB	IGFBP4	0.912
TNC	TIMP1	0.912
VCAN	ADAM10	0.912
SDC2	IGFBP5	0.912
CALU	LAMB1	0.912
LAMB2	APP	0.912
MATN3	LAMB1	0.912
APP	LAMC1	0.912
SPARCL1	IGFBP5	0.912
CST3	ADAM10	0.912
FSTL1	EVA1A	0.912
LAMB2	P4HB	0.912
GPC3	FSTL1	0.912
APOE	IGFBP5	0.912
CKAP4	PRSS23	0.912
IGFBP4	CDH2	0.912
ITGB2	ADAM10	0.912
CSF1	IGFBP5	0.912
IGFBP5	FSTL3	0.912
EVA1A	LAMB1	0.912
IGFBP3	ADAM10	0.912
MFGE8	ADAM10	0.912
P4HB	IGFBP5	0.912
MATN3	ALB	0.912
CALU	FBN1	0.912
PCSK9	IGFBP4	0.912
IGFBP3	LAMC1	0.912
LTBP1	FSTL3	0.912
ADAM10	BMP4	0.912
IGFBP7	STC2	0.912
IGFBP7	CDH2	0.912
TNC	EVA1A	0.911
LAMB2	FAM20C	0.911
LGALS1	FSTL3	0.911
LAMC1	RCN1	0.911
MXRA8	FSTL3	0.911
MATN3	IGFBP1	0.911
FSTL1	MFGE8	0.911
MSLN	IGFBP3	0.911
CKAP4	FN1	0.911
CSF1	ADAM10	0.911
HSP90B1	LGALS1	0.911
FSTL1	PRSS23	0.911
IGFBP5	RCN1	0.911
MXRA8	GPC3	0.911
VWA1	APOE	0.911
FBN1	IGFBP4	0.911
CYR61	MATN3	0.911
SPP1	LAMB1	0.911
CSF1	LGALS1	0.911
FAM20C	IGFBP7	0.911
APP	LAMB1	0.911
GPC3	ADAM10	0.911
MATN3	FSTL1	0.911
MATN3	TNC	0.911
CALU	LGALS1	0.911
CYR61	PRSS23	0.911
PRSS23	TIMP1	0.911
CYR61	APP	0.911
LAMB2	FBN1	0.911
CYR61	GPC3	0.911
IGFBP4	TNC	0.911
FAM20C	IGFBP4	0.911
FBN1	FAM20C	0.911
GAS6	PCSK9	0.911
P4HB	LAMC1	0.911
IGFBP7	APOE	0.911
GAS6	FSTL3	0.911
CSF1	FBN1	0.911
CALU	GAS6	0.911
P4HB	LGALS1	0.911
P4HB	CDH2	0.911
MATN3	STC2	0.911
CST3	STC2	0.91
GAS6	IGFBP7	0.91
GAS6	FBN1	0.91
LAMC1	EVA1A	0.91
GAS6	TIMP1	0.91
CYR61	RCN1	0.91
CALU	CYR61	0.91
CALU	RCN1	0.91
HSP90B1	FSTL1	0.91
SPARCL1	MXRA8	0.91
FSTL1	STC2	0.91
LTBP1	GPC3	0.91
MATN3	IGFBP3	0.91
IL6	LAMB1	0.91
MSLN	IGFBP5	0.91
CYR61	PCSK9	0.91
VWA1	MXRA8	0.91
LAMB2	RCN1	0.91
IGFBP7	LGALS1	0.91
SDC2	ADAM10	0.91
LAMB1	FSTL3	0.91
CST3	IGFBP1	0.91
GAS6	LGALS1	0.91
MXRA8	FN1	0.91
IL6	STC2	0.91
LTBP1	IL6	0.91
HSP90B1	ADAM10	0.91
CDH2	STC2	0.91
SPARCL1	LAMC1	0.91
MXRA8	IGFBP4	0.91
SDC2	APP	0.91
CYR61	APOE	0.909
IL6	MATN3	0.909
IGFBP4	LGALS1	0.909
CST3	LGALS1	0.909
PRSS23	LAMB1	0.909
IGFBP7	LAMC1	0.909
PCSK9	TNC	0.909
CALU	CSF1	0.909
CDH2	MFGE8	0.909
CYR61	MSLN	0.909
IL6	PRSS23	0.909
APP	IGFBP5	0.909
MXRA8	CYR61	0.909
SDC2	PRSS23	0.909
SPP1	ADAM10	0.909
SPARCL1	CDH2	0.909
CALU	IGFBP3	0.909
CYR61	FSTL3	0.909
CKAP4	TIMP1	0.909
GPC3	LAMC1	0.909
CALU	LAMB2	0.909
FAM20C	TIMP1	0.909
CST3	CSF1	0.909
MFGE8	LAMB1	0.909
CYR61	CKAP4	0.909
TNC	RCN1	0.909
LTBP1	IGFBP7	0.909
CST3	MFGE8	0.909
FSTL1	LGALS1	0.909
ITGAM	CYR61	0.909
CKAP4	FSTL1	0.909
IGFBP4	FSTL3	0.909
PRSS23	VCAN	0.909
CSF1	IGFBP7	0.909
PRSS23	IGFBP5	0.909
VWA1	LAMB2	0.909
MXRA8	IGFBP7	0.908
LAMB2	MFGE8	0.908
SPP1	LAMC1	0.908
CKAP4	LGALS1	0.908
MATN3	CDH2	0.908
CKAP4	ALB	0.908
IGFBP5	LGALS1	0.908
IGFBP3	MFGE8	0.908
HSP90B1	CDH2	0.908
MFGE8	TIMP1	0.908
SPARCL1	TIMP1	0.908
CYR61	LGALS1	0.908
MSLN	MFGE8	0.908
FBN1	EVA1A	0.908
FBN1	MFGE8	0.908
MFGE8	LGALS1	0.908
MATN3	IGFBP4	0.908
GPC3	STC2	0.908
ADAM10	LAMC1	0.908
ALB	EVA1A	0.908
IGFBP1	ADAM10	0.908
LAMB2	SPP1	0.908
CALU	SPP1	0.908
STC2	EVA1A	0.908
MXRA8	FAM20C	0.908
PRSS23	IGFBP4	0.908
MFGE8	FSTL3	0.908
LTBP1	APOE	0.908
FBN1	FSTL3	0.908
CALU	TNC	0.908
LAMB2	IGFBP7	0.908
CST3	CDH2	0.908
MSLN	FSTL3	0.908
GAS6	FSTL1	0.908
GAS6	P4HB	0.908
PCSK9	LAMC1	0.908
HSP90B1	STC2	0.908
SDC2	TNC	0.908
FAM20C	SDC2	0.908
CDH2	LGALS1	0.907
TNC	LGALS1	0.907
CKAP4	LAMC1	0.907
MXRA8	LGALS1	0.907
SPARCL1	LAMB2	0.907
LAMB2	MATN3	0.907
LAMB2	IL6	0.907
MFGE8	IGFBP5	0.907
FSTL1	APP	0.907
GPC3	FSTL3	0.907
SPP1	HSP90B1	0.907
CALU	STC2	0.907
IGFBP3	RCN1	0.907
SDC2	FSTL3	0.907
IGFBP3	P4HB	0.907
MATN3	SDC2	0.907
GAS6	LAMC1	0.907
GAS6	LAMB1	0.907
VWA1	GAS6	0.907
IGFBP4	EVA1A	0.907
MSLN	LGALS1	0.907
APOE	LAMB1	0.907
MATN3	APP	0.907
LAMB2	LGALS1	0.907
P4HB	STC2	0.907
ALB	PRSS23	0.907
MATN3	FSTL3	0.907
CYR61	P4HB	0.907
LAMB2	TIMP1	0.907
CKAP4	RCN1	0.907
LTBP1	MATN3	0.907
FBN1	STC2	0.907
APP	RCN1	0.907
GAS6	IGFBP5	0.907
CALU	PRSS23	0.907
SPP1	TNC	0.907
IGFBP1	EVA1A	0.907
MATN3	SPP1	0.907
MATN3	FBN1	0.907
PRSS23	EVA1A	0.907
SPP1	FSTL1	0.907
CKAP4	LAMB1	0.907
GPC3	PCSK9	0.907
IGFBP7	APP	0.907
VWA1	IGFBP5	0.907
ALB	FSTL3	0.907
IGFBP7	TNC	0.907
ALB	RCN1	0.907
MFGE8	LAMC1	0.906
MSLN	ADAM10	0.906
MXRA8	CSF1	0.906
SDC2	IGFBP7	0.906
VWA1	PCSK9	0.906
IGFBP1	TNC	0.906
SPARCL1	TNC	0.906
LAMB2	PRSS23	0.906
FSTL1	APOE	0.906
GPC3	IGFBP4	0.906
STC2	BMP4	0.906
FAM20C	MFGE8	0.906
CALU	SDC2	0.906
HSP90B1	LAMC1	0.906
MSLN	LAMB1	0.906
LAMB2	BMP4	0.906
PRSS23	LAMC1	0.906
MSLN	FSTL1	0.906
STC2	LGALS1	0.906
GAS6	RCN1	0.906
APOE	FSTL3	0.906
GPC3	APP	0.906
IGFBP7	RCN1	0.906
VWA1	TNC	0.906
SPARCL1	IGFBP4	0.906
TIMP1	RCN1	0.906
MATN3	GPC3	0.906
CSF1	FSTL3	0.906
PRSS23	LGALS1	0.906
HSP90B1	VCAN	0.906
HSP90B1	TIMP1	0.906
VWA1	IGFBP4	0.906
SPARCL1	MFGE8	0.906
SPARCL1	CST3	0.906
P4HB	CSF1	0.906
MXRA8	LAMB1	0.906
IL6	LAMC1	0.906
GPC3	IGFBP7	0.906
MSLN	IGFBP4	0.906
P4HB	MFGE8	0.906
CKAP4	ITGAV	0.906
IL6	SDC2	0.906
FAM20C	APOE	0.906
VWA1	LAMB1	0.906
CALU	ADAM10	0.905
MATN3	EVA1A	0.905
PCSK9	BMP4	0.905
LAMB2	EVA1A	0.905
FAM20C	EVA1A	0.905
P4HB	FSTL3	0.905
CSF1	TNC	0.905
MATN3	IGFBP5	0.905
CSF1	LAMC1	0.905
LTBP1	STC2	0.905
CYR61	HSP90B1	0.905
CSF1	HSP90B1	0.905
FAM20C	TNC	0.905
VWA1	IL6	0.905
CYR61	ADAM10	0.905
GAS6	PRSS23	0.905
MXRA8	LAMC1	0.905
VWA1	LTBP1	0.905
IGFBP3	HSP90B1	0.905
P4HB	VCAN	0.905
LAMB2	MSLN	0.905
CSF1	FAM20C	0.905
PRSS23	RCN1	0.905
CKAP4	EVA1A	0.905
FBN1	RCN1	0.905
VWA1	CST3	0.905
SPARCL1	LTBP1	0.905
TNC	STC2	0.905
CKAP4	TNC	0.905
MSLN	PCSK9	0.905
LAMB2	CKAP4	0.905
LTBP1	EVA1A	0.905
LTBP1	IGFBP1	0.905
LAMB2	STC2	0.905
MXRA8	CST3	0.905
CALU	EVA1A	0.905
LAMC1	FSTL3	0.905
APP	IGFBP4	0.905
STC2	TIMP1	0.905
GPC3	CSF1	0.905
CST3	IGFBP4	0.905
MXRA8	SDC2	0.905
HSP90B1	LAMB1	0.905
MXRA8	TIMP1	0.905
VWA1	STC2	0.905
ALB	STC2	0.905
PRSS23	ADAM10	0.905
TNC	FSTL3	0.905
EVA1A	FSTL3	0.905
SPP1	PCSK9	0.905
LAMB2	CST3	0.905
EVA1A	TIMP1	0.905
MXRA8	MFGE8	0.905
IGFBP4	MFGE8	0.905
MATN3	PCSK9	0.905
SDC2	IGFBP4	0.905
IGFBP4	RCN1	0.904
PCSK9	LAMB1	0.904
LAMB2	GPC3	0.904
PCSK9	IGFBP7	0.904
P4HB	EVA1A	0.904
APP	PRSS23	0.904
IGFBP3	CKAP4	0.904
MSLN	FBN1	0.904
FAM20C	BMP4	0.904
VWA1	CYR61	0.904
PCSK9	EVA1A	0.904
CALU	VCAN	0.904
MSLN	GAS6	0.904
MSLN	EVA1A	0.904
PCSK9	TIMP1	0.904
VCAN	RCN1	0.904
EVA1A	RCN1	0.904
LGALS1	RCN1	0.904
SDC2	EVA1A	0.904
GPC3	GAS6	0.904
PRSS23	FSTL3	0.904
APP	LGALS1	0.904
VWA1	SPP1	0.904
P4HB	BMP4	0.904
CKAP4	CDH2	0.904
CST3	BMP4	0.904
CSF1	RCN1	0.904
CST3	SDC2	0.904
MSLN	PRSS23	0.904
VWA1	FSTL1	0.904
SPARCL1	SDC2	0.904
GAS6	SDC2	0.904
PRSS23	STC2	0.904
LTBP1	LGALS1	0.904
CKAP4	IGFBP4	0.904
VWA1	FBN1	0.904
SDC2	STC2	0.904
GAS6	TNC	0.904
P4HB	SDC2	0.904
LAMB2	CDH2	0.904
LAMB2	APOE	0.904
MFGE8	TNC	0.904
VWA1	FSTL3	0.904
CKAP4	IGFBP7	0.904
IGFBP7	EVA1A	0.904
GAS6	EVA1A	0.904
FBN1	HSP90B1	0.904
ITGB2	ITGB5	0.904
SPARCL1	GAS6	0.904
CKAP4	APP	0.904
FAM20C	LGALS1	0.904
P4HB	TNC	0.904
CKAP4	STC2	0.904
CKAP4	VCAN	0.904
CYR61	FAM20C	0.904
LTBP1	RCN1	0.904
P4HB	FSTL1	0.904
MFGE8	STC2	0.904
SDC2	RCN1	0.904
ADAM10	IGFBP5	0.903
LTBP1	CKAP4	0.903
APP	FSTL3	0.903
FAM20C	LAMB1	0.903
IL6	EVA1A	0.903
MATN3	MSLN	0.903
SDC2	PCSK9	0.903
MATN3	CKAP4	0.903
MFGE8	RCN1	0.903
VWA1	MFGE8	0.903
MXRA8	EVA1A	0.903
PRSS23	IGFBP1	0.903
MSLN	VCAN	0.903
HSP90B1	EVA1A	0.903
VWA1	FAM20C	0.903
EVA1A	LGALS1	0.903
PCSK9	ADAM10	0.903
VWA1	TIMP1	0.903
MSLN	APOE	0.903
VWA1	CDH2	0.903
PCSK9	PRSS23	0.903
CST3	PRSS23	0.903
SPARCL1	IL6	0.903
CSF1	LAMB1	0.903
CDH2	EVA1A	0.903
FAM20C	LAMC1	0.903
GPC3	MFGE8	0.903
LTBP1	MSLN	0.903
MXRA8	BMP4	0.903
MATN3	MFGE8	0.903
APP	IGFBP1	0.903
MATN3	LGALS1	0.903
PCSK9	FSTL1	0.903
CKAP4	SDC2	0.903
MXRA8	CKAP4	0.903
CSF1	SDC2	0.903
CKAP4	FAM20C	0.903
MFGE8	BMP4	0.903
LAMC1	APOE	0.903
MSLN	BMP4	0.903
MATN3	FAM20C	0.903
FBN1	IGFBP1	0.903
LTBP1	GAS6	0.903
CALU	MATN3	0.903
BMP4	EVA1A	0.903
CALU	IGFBP5	0.903
SPARCL1	FSTL3	0.903
MXRA8	STC2	0.903
PCSK9	STC2	0.903
IGFBP5	EVA1A	0.903
MXRA8	APOE	0.903
CALU	IGFBP4	0.903
VWA1	IGFBP3	0.903
FBN1	PCSK9	0.903
MSLN	TNC	0.903
APP	STC2	0.903
VCAN	FSTL3	0.903
IGFBP1	LAMC1	0.903
PRSS23	CDH2	0.903
VWA1	SDC2	0.902
SPARCL1	P4HB	0.902
MXRA8	ALB	0.902
SDC2	MFGE8	0.902
SDC2	LGALS1	0.902
CST3	PCSK9	0.902
MSLN	SDC2	0.902
CST3	P4HB	0.902
CALU	GPC3	0.902
MATN3	GAS6	0.902
P4HB	PRSS23	0.902
GAS6	STC2	0.902
GPC3	RCN1	0.902
GAS6	VCAN	0.902
LAMB2	PCSK9	0.902
LAMB2	HSP90B1	0.902
VWA1	IGFBP7	0.902
CALU	MXRA8	0.902
P4HB	IGFBP1	0.902
CALU	IGFBP1	0.902
CKAP4	FSTL3	0.902
MSLN	FAM20C	0.902
CKAP4	CSF1	0.902
MATN3	TIMP1	0.902
PCSK9	FSTL3	0.902
SPARCL1	LGALS1	0.902
MATN3	RCN1	0.902
CALU	MFGE8	0.902
CST3	LAMB1	0.902
FSTL1	ADAM10	0.902
MFGE8	EVA1A	0.902
CSF1	PRSS23	0.902
CALU	SPARCL1	0.902
PRSS23	MFGE8	0.902
LTBP1	CSF1	0.902
VWA1	LGALS1	0.902
LTBP1	P4HB	0.902
MXRA8	CDH2	0.902
CALU	FSTL3	0.902
CST3	LAMC1	0.902
IL6	RCN1	0.902
SPARCL1	CKAP4	0.902
MXRA8	P4HB	0.902
PRSS23	BMP4	0.902
CALU	MSLN	0.902
SPARCL1	IGFBP3	0.902
CALU	IGFBP7	0.902
CST3	FSTL1	0.902
BMP4	RCN1	0.902
CKAP4	IGFBP5	0.902
SPARCL1	RCN1	0.902
MXRA8	MATN3	0.902
MXRA8	PRSS23	0.902
MSLN	HSP90B1	0.902
MSLN	IGFBP7	0.902
CSF1	EVA1A	0.902
MSLN	LAMC1	0.902
FSTL3	RCN1	0.902
P4HB	FAM20C	0.902
FSTL1	IGFBP1	0.902
APP	EVA1A	0.902
VWA1	PRSS23	0.902
SPARCL1	EVA1A	0.902
MXRA8	MSLN	0.902
CDH2	RCN1	0.902
ADAM10	LAMB1	0.902
SPARCL1	PRSS23	0.902
SPARCL1	MATN3	0.902
MXRA8	RCN1	0.902
LAMB2	VCAN	0.902
CST3	FBN1	0.902
SPP1	RCN1	0.902
MXRA8	VCAN	0.902
MSLN	P4HB	0.902
VWA1	HSP90B1	0.901
PCSK9	IGFBP5	0.901
HSP90B1	IGFBP1	0.901
HSP90B1	IGFBP5	0.901
FAM20C	HSP90B1	0.901
GAS6	IGFBP1	0.901
CST3	HSP90B1	0.901
IGFBP4	ADAM10	0.901
SPARCL1	CSF1	0.901
CST3	VCAN	0.901
GAS6	HSP90B1	0.901
SPARCL1	ADAM10	0.901
MSLN	STC2	0.901
ITGAM	CKAP4	0.901
SPARCL1	HSP90B1	0.901
MFGE8	VCAN	0.901
VWA1	P4HB	0.901
SPP1	CKAP4	0.901
TNC	ADAM10	0.901
GPC3	HSP90B1	0.901
CST3	MSLN	0.901
CKAP4	MFGE8	0.901
MATN3	IGFBP7	0.901
IL6	CKAP4	0.9
MXRA8	IL6	0.9
MATN3	CST3	0.9
MSLN	APP	0.9
GPC3	LGALS1	0.9
FAM20C	RCN1	0.9
SPARCL1	PCSK9	0.9
GPC3	PRSS23	0.9
CST3	TNC	0.9
GPC3	CKAP4	0.9
ADAM10	FSTL3	0.9
VWA1	CKAP4	0.9
HSP90B1	IGFBP4	0.9
CST3	GPC3	0.9
CST3	RCN1	0.9
VWA1	GPC3	0.9
SDC2	HSP90B1	0.9
STC2	APOE	0.9
FAM20C	ADAM10	0.9
MXRA8	SPP1	0.9
CST3	CKAP4	0.9
ITGB2	CKAP4	0.9
PCSK9	LGALS1	0.9
MATN3	CSF1	0.9
VWA1	CSF1	0.9
IGFBP7	ADAM10	0.9
CKAP4	IGFBP1	0.9
PRSS23	APOE	0.9
CDH2	FSTL3	0.9
PCSK9	RCN1	0.9
IGFBP1	RCN1	0.9
GPC3	EVA1A	0.9
SPP1	EVA1A	0.9
HSP90B1	BMP4	0.9
HSP90B1	PRSS23	0.9
MXRA8	HSP90B1	0.9
VWA1	MSLN	0.9
ADAM10	LGALS1	0.9
ADAM10	EVA1A	0.9
CKAP4	APOE	0.9
GPC3	P4HB	0.9
SPARCL1	STC2	0.9
LTBP1	HSP90B1	0.9
HSP90B1	FSTL3	0.9
CKAP4	ADAM10	0.9
MXRA8	PCSK9	0.9
MATN3	APOE	0.9
CALU	CST3	0.9
ADAM10	RCN1	0.9
IGFBP1	MFGE8	0.9
MSLN	CKAP4	0.9
CALU	VWA1	0.9
LAMB2	ADAM10	0.9
MXRA8	ADAM10	0.9
CKAP4	PCSK9	0.9
LTBP1	CST3	0.9
PCSK9	MFGE8	0.9
GPC3	FAM20C	0.9
HSP90B1	TNC	0.9
STC2	ADAM10	0.9
CKAP4	BMP4	0.9
VWA1	VCAN	0.9
CST3	EVA1A	0.9
VWA1	EVA1A	0.9
CKAP4	GAS6	0.9
PCSK9	VCAN	0.9
MSLN	RCN1	0.9
P4HB	IGFBP7	0.9
CALU	BMP4	0.9
APOE	RCN1	0.9
LTBP1	PCSK9	0.9
SPP1	PRSS23	0.9
MXRA8	IGFBP1	0.9
VWA1	IGFBP1	0.9
VCAN	EVA1A	0.9
SPARCL1	MSLN	0.9
HSP90B1	IGFBP7	0.9
SDC2	IGFBP1	0.9
SPARCL1	IGFBP1	0.9
CSF1	STC2	0.9
FAM20C	PRSS23	0.9
LAMB2	IGFBP1	0.9

Gene Ontology Semantic Similarity

Download Tab separated file

#	5034 (P4HB)	2335 (FN1)	351 (APP)	3915 (LAMC1)	3684 (ITGAM)	813 (CALU)	3484 (IGFBP1)	3693 (ITGB5)	3913 (LAMB2)	3486 (IGFBP3)	7184 (HSP90B1)	3569 (IL6)	2200 (FBN1)	3491 (CYR61)	213 (ALB)	6696 (SPP1)	1471 (CST3)	2621 (GAS6)	4052 (LTBP1)	1000 (CDH2)	3689 (ITGB2)	11167 (FSTL1)	102 (ADAM10)	255738 (PCSK9)	3490 (IGFBP7)	2719 (GPC3)	8404 (SPARCL1)	1435 (CSF1)	4240 (MFGE8)	1462 (VCAN)	3685 (ITGAV)	56975 (FAM20C)	348 (APOE)	652 (BMP4)	3487 (IGFBP4)	4148 (MATN3)	3371 (TNC)	6383 (SDC2)	54587 (MXRA8)	7076 (TIMP1)	10970 (CKAP4)	64856 (VWA1)	10232 (MSLN)	8614 (STC2)	3488 (IGFBP5)	3912 (LAMB1)	3956 (LGALS1)	10272 (FSTL3)
5034 (P4HB)	1.00	0.58	0.58	0.26	0.57	0.45	0.53	0.56	0.23	0.49	0.56	0.50	0.51	0.37	0.54	0.47	0.45	0.42	0.44	0.57	0.61	1.00	0.52	0.54	0.44	0.43	0.48	0.54	0.26	0.44	0.58	0.42	0.47	0.52	0.52	0.44	0.47	0.51	0.48	0.44	1.00	0.26	1.00	0.44	0.51	0.44	0.57	0.52
2335 (FN1)	0.58	1.00	0.71	1.00	0.66	0.63	0.69	0.71	0.38	0.62	0.63	0.68	0.81	0.56	0.64	0.65	0.65	0.59	0.68	0.68	0.68	1.00	0.65	0.59	0.73	0.61	0.68	0.71	1.00	0.72	0.68	0.57	0.64	0.67	0.69	0.73	0.73	0.69	0.48	0.63	0.37	1.00	1.00	0.59	0.66	0.73	0.63	0.69
351 (APP)	0.58	0.71	1.00	0.26	0.70	0.66	0.73	0.69	0.26	0.64	0.71	0.73	0.61	0.39	0.70	0.69	0.81	0.65	0.60	0.71	0.65	1.00	0.62	0.65	0.65	0.75	0.65	0.77	0.26	0.63	0.65	0.57	0.58	0.70	0.73	0.65	0.67	0.75	0.48	0.75	0.75	0.26	1.00	0.67	0.70	0.63	0.75	0.71
3915 (LAMC1)	0.26	1.00	0.26	1.00	0.26	0.26	0.26	0.26	1.00	0.26	0.26	0.26	1.00	0.14	0.34	0.26	0.26	0.26	1.00	0.26	0.26	0.26	0.26	0.26	1.00	0.26	0.26	0.26	1.00	0.82	0.26	0.26	0.76	0.34	0.26	1.00	1.00	0.26	0.48	0.26	0.16	1.00	0.26	0.21	0.26	1.00	0.26	0.26
3684 (ITGAM)	0.57	0.66	0.70	0.26	1.00	0.74	0.76	0.77	0.28	0.67	0.67	0.75	0.59	0.40	0.61	0.78	0.63	0.54	0.63	0.75	0.81	1.00	0.59	0.59	0.73	0.71	0.71	0.75	0.26	0.69	0.66	0.59	0.55	0.71	0.77	0.73	0.74	0.80	0.48	0.61	0.37	0.26	1.00	0.63	0.77	0.67	0.75	0.79
813 (CALU)	0.45	0.63	0.66	0.26	0.74	1.00	0.72	0.71	0.29	0.73	0.80	0.71	0.67	0.41	0.61	0.74	0.56	0.48	0.56	0.86	0.63	1.00	0.53	0.55	0.65	0.62	0.87	0.72	0.26	0.61	0.62	0.60	0.54	0.67	0.73	0.65	0.69	0.77	0.48	0.61	0.37	0.26	1.00	0.58	0.73	0.59	0.68	0.76
3484 (IGFBP1)	0.53	0.69	0.73	0.26	0.76	0.72	1.00	0.76	0.27	0.85	0.68	0.79	0.60	0.43	0.61	0.76	0.62	0.59	0.63	0.74	0.67	1.00	0.63	0.62	0.71	0.69	0.70	0.78	0.26	0.68	0.71	0.59	0.55	0.74	0.98	0.71	0.72	0.78	0.48	0.62	0.37	0.26	1.00	0.60	0.94	0.66	0.73	0.77
3693 (ITGB5)	0.56	0.71	0.69	0.26	0.77	0.71	0.76	1.00	0.28	0.64	0.63	0.74	0.65	0.70	0.58	0.77	0.58	0.50	0.58	0.74	0.73	1.00	0.65	0.56	0.69	0.66	0.70	0.74	0.26	0.64	0.69	0.52	0.51	0.69	0.77	0.69	0.72	0.80	0.48	0.56	0.37	0.26	1.00	0.60	0.75	0.62	0.72	0.81
3913 (LAMB2)	0.23	0.38	0.26	1.00	0.28	0.29	0.27	0.28	1.00	0.25	0.25	0.27	0.50	0.16	0.30	0.32	0.25	0.22	0.54	0.27	0.25	0.34	0.24	0.24	0.78	0.28	0.28	0.26	1.00	0.57	0.24	0.25	0.35	0.31	0.27	0.78	0.68	0.29	0.64	0.24	0.21	1.00	0.34	0.24	0.27	0.87	0.29	0.29
3486 (IGFBP3)	0.49	0.62	0.64	0.26	0.67	0.73	0.85	0.64	0.25	1.00	0.68	0.65	0.62	0.35	0.62	0.65	0.59	0.54	0.57	0.74	0.61	1.00	0.55	0.56	0.61	0.62	0.71	0.67	0.26	0.59	0.68	0.60	0.58	0.64	0.82	0.61	0.63	0.67	0.48	0.64	0.37	0.26	1.00	0.52	0.85	0.59	0.62	0.70
7184 (HSP90B1)	0.56	0.63	0.71	0.26	0.67	0.80	0.68	0.63	0.25	0.68	1.00	0.65	0.63	0.37	0.66	0.65	0.55	0.50	0.55	0.78	0.61	1.00	0.54	0.67	0.60	0.58	0.75	0.67	0.26	0.58	0.61	0.57	0.58	0.63	0.68	0.60	0.63	0.68	0.48	0.59	1.00	0.26	1.00	0.60	0.66	0.57	0.79	0.67
3569 (IL6)	0.50	0.68	0.73	0.26	0.75	0.71	0.79	0.74	0.27	0.65	0.65	1.00	0.58	0.47	0.60	0.75	0.61	0.56	0.61	0.74	0.66	1.00	0.61	0.58	0.70	0.68	0.69	0.87	0.26	0.66	0.64	0.57	0.53	0.77	0.80	0.70	0.71	0.77	0.48	0.65	0.37	0.26	1.00	0.59	0.74	0.65	0.71	0.76
2200 (FBN1)	0.51	0.81	0.61	1.00	0.59	0.67	0.60	0.65	0.50	0.62	0.63	0.58	1.00	0.60	0.61	0.56	0.54	0.49	0.66	0.71	0.62	1.00	0.57	0.53	0.73	0.52	0.67	0.64	1.00	0.70	0.62	0.52	0.67	0.58	0.60	0.73	0.74	0.63	0.48	0.54	0.37	1.00	1.00	0.48	0.59	0.73	0.54	0.60
3491 (CYR61)	0.37	0.56	0.39	0.14	0.40	0.41	0.43	0.70	0.16	0.35	0.37	0.47	0.60	1.00	0.36	0.41	0.31	0.36	0.31	0.42	0.47	0.50	0.43	0.35	0.36	0.35	0.45	0.45	0.14	0.48	0.40	0.30	0.39	0.41	0.44	0.36	0.37	0.41	0.22	0.33	0.21	0.14	0.50	0.32	0.39	0.32	0.38	0.49
213 (ALB)	0.54	0.64	0.70	0.34	0.61	0.61	0.61	0.58	0.30	0.62	0.66	0.60	0.61	0.36	1.00	0.59	0.57	0.54	0.54	0.67	0.58	1.00	0.54	0.58	0.57	0.56	0.61	0.64	0.34	0.56	0.59	0.57	0.63	0.60	0.60	0.57	0.59	0.64	0.64	0.58	0.75	0.34	1.00	0.54	0.60	0.57	0.64	0.61
6696 (SPP1)	0.47	0.65	0.69	0.26	0.78	0.74	0.76	0.77	0.32	0.65	0.65	0.75	0.56	0.41	0.59	1.00	0.59	0.50	0.59	0.75	0.65	1.00	0.56	0.57	0.71	0.68	0.83	0.75	0.26	0.66	0.68	0.54	0.52	0.70	0.77	0.71	0.73	0.82	0.48	0.57	0.37	0.26	1.00	0.62	0.77	0.64	0.74	0.81
1471 (CST3)	0.45	0.65	0.81	0.26	0.63	0.56	0.62	0.58	0.25	0.59	0.55	0.61	0.54	0.31	0.57	0.59	1.00	0.62	0.52	0.66	0.66	1.00	0.52	0.54	0.55	0.74	0.57	0.67	0.26	0.54	0.62	0.48	0.59	0.60	0.62	0.55	0.58	0.67	0.48	0.78	0.37	0.26	1.00	0.54	0.62	0.54	0.57	0.62
2621 (GAS6)	0.42	0.59	0.65	0.26	0.54	0.48	0.59	0.50	0.22	0.54	0.50	0.56	0.49	0.36	0.54	0.50	0.62	1.00	0.47	0.58	0.56	1.00	0.52	0.53	0.47	0.55	0.50	0.59	0.26	0.48	0.64	0.43	0.54	0.56	0.58	0.47	0.50	0.53	0.48	0.59	0.37	0.26	1.00	0.43	0.53	0.47	0.48	0.53
4052 (LTBP1)	0.44	0.68	0.60	1.00	0.63	0.56	0.63	0.58	0.54	0.57	0.55	0.61	0.66	0.31	0.54	0.59	0.52	0.47	1.00	0.65	0.64	1.00	0.50	0.52	0.76	0.53	0.57	0.63	1.00	0.67	0.65	0.61	0.53	0.60	0.62	0.76	0.76	0.63	0.48	0.50	0.37	1.00	1.00	0.48	0.62	0.76	0.56	0.62
1000 (CDH2)	0.57	0.68	0.71	0.26	0.75	0.86	0.74	0.74	0.27	0.74	0.78	0.74	0.71	0.42	0.67	0.75	0.66	0.58	0.65	1.00	0.69	1.00	0.67	0.61	0.72	0.71	0.81	0.79	0.26	0.69	0.66	0.68	0.63	0.71	0.74	0.72	0.73	0.78	0.48	0.68	0.37	0.26	1.00	0.68	0.74	0.68	0.73	0.76
3689 (ITGB2)	0.61	0.68	0.65	0.26	0.81	0.63	0.67	0.73	0.25	0.61	0.61	0.66	0.62	0.47	0.58	0.65	0.66	0.56	0.64	0.69	1.00	1.00	0.67	0.57	0.62	0.61	0.64	0.67	0.26	0.61	0.73	0.55	0.58	0.64	0.67	0.62	0.64	0.67	0.48	0.57	0.37	0.26	1.00	0.55	0.66	0.60	0.63	0.68
11167 (FSTL1)	1.00	1.00	1.00	0.26	1.00	1.00	1.00	1.00	0.34	1.00	1.00	1.00	1.00	0.50	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.26	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.48	1.00	0.37	0.26	1.00	0.82	1.00	1.00	1.00	1.00
102 (ADAM10)	0.52	0.65	0.62	0.26	0.59	0.53	0.63	0.65	0.24	0.55	0.54	0.61	0.57	0.43	0.54	0.56	0.52	0.52	0.50	0.67	0.67	1.00	1.00	0.64	0.52	0.51	0.56	0.69	0.26	0.51	0.64	0.49	0.53	0.61	0.62	0.52	0.55	0.60	0.48	0.51	0.37	0.26	1.00	0.56	0.58	0.52	0.53	0.59
255738 (PCSK9)	0.54	0.59	0.65	0.26	0.59	0.55	0.62	0.56	0.24	0.56	0.67	0.58	0.53	0.35	0.58	0.57	0.54	0.53	0.52	0.61	0.57	1.00	0.64	1.00	0.54	0.55	0.56	0.60	0.26	0.54	0.58	0.50	0.58	0.58	0.61	0.54	0.56	0.59	0.48	0.54	1.00	0.26	1.00	0.49	0.58	0.54	0.64	0.59
3490 (IGFBP7)	0.44	0.73	0.65	1.00	0.73	0.65	0.71	0.69	0.78	0.61	0.60	0.70	0.73	0.36	0.57	0.71	0.55	0.47	0.76	0.72	0.62	1.00	0.52	0.54	1.00	0.60	0.64	0.71	1.00	0.82	0.62	0.48	0.55	0.67	0.71	1.00	0.96	0.75	0.48	0.53	0.37	1.00	1.00	0.56	0.71	0.95	0.66	0.74
2719 (GPC3)	0.43	0.61	0.75	0.26	0.71	0.62	0.69	0.66	0.28	0.62	0.58	0.68	0.52	0.35	0.56	0.68	0.74	0.55	0.53	0.71	0.61	1.00	0.51	0.55	0.60	1.00	0.62	0.69	0.26	0.57	0.61	0.46	0.52	0.65	0.69	0.60	0.64	0.73	0.48	0.75	0.37	0.26	1.00	0.54	0.69	0.56	0.63	0.72
8404 (SPARCL1)	0.48	0.68	0.65	0.26	0.71	0.87	0.70	0.70	0.28	0.71	0.75	0.69	0.67	0.45	0.61	0.83	0.57	0.50	0.57	0.81	0.64	1.00	0.56	0.56	0.64	0.62	1.00	0.70	0.26	0.61	0.67	0.60	0.55	0.66	0.70	0.64	0.66	0.72	0.48	0.61	0.37	0.26	1.00	0.55	0.70	0.60	0.66	0.75
1435 (CSF1)	0.54	0.71	0.77	0.26	0.75	0.72	0.78	0.74	0.26	0.67	0.67	0.87	0.64	0.45	0.64	0.75	0.67	0.59	0.63	0.79	0.67	1.00	0.69	0.60	0.71	0.69	0.70	1.00	0.26	0.68	0.65	0.60	0.59	0.77	0.79	0.71	0.72	0.82	0.48	0.67	0.37	0.26	1.00	0.70	0.74	0.67	0.72	0.76
4240 (MFGE8)	0.26	1.00	0.26	1.00	0.26	0.26	0.26	0.26	1.00	0.26	0.26	0.26	1.00	0.14	0.34	0.26	0.26	0.26	1.00	0.26	0.26	0.26	0.26	0.26	1.00	0.26	0.26	0.26	1.00	0.82	0.26	0.26	0.76	0.34	0.26	1.00	1.00	0.26	0.48	0.26	0.16	1.00	0.26	0.21	0.26	1.00	0.26	0.26
1462 (VCAN)	0.44	0.72	0.63	0.82	0.69	0.61	0.68	0.64	0.57	0.59	0.58	0.66	0.70	0.48	0.56	0.66	0.54	0.48	0.67	0.69	0.61	1.00	0.51	0.54	0.82	0.57	0.61	0.68	0.82	1.00	0.61	0.48	0.55	0.64	0.67	0.82	0.82	0.70	0.48	0.52	0.37	0.82	1.00	0.53	0.67	0.79	0.61	0.69
3685 (ITGAV)	0.58	0.68	0.65	0.26	0.66	0.62	0.71	0.69	0.24	0.68	0.61	0.64	0.62	0.40	0.59	0.68	0.62	0.64	0.65	0.66	0.73	1.00	0.64	0.58	0.62	0.61	0.67	0.65	0.26	0.61	1.00	0.57	0.55	0.63	0.70	0.62	0.63	0.65	0.48	0.61	0.37	0.26	1.00	0.54	0.71	0.60	0.62	0.67
56975 (FAM20C)	0.42	0.57	0.57	0.26	0.59	0.60	0.59	0.52	0.25	0.60	0.57	0.57	0.52	0.30	0.57	0.54	0.48	0.43	0.61	0.68	0.55	1.00	0.49	0.50	0.48	0.46	0.60	0.60	0.26	0.48	0.57	1.00	0.50	0.57	0.58	0.48	0.53	0.59	0.48	0.54	0.37	0.26	1.00	0.44	0.58	0.47	0.50	0.58
348 (APOE)	0.47	0.64	0.58	0.76	0.55	0.54	0.55	0.51	0.35	0.58	0.58	0.53	0.67	0.39	0.63	0.52	0.59	0.54	0.53	0.63	0.58	1.00	0.53	0.58	0.55	0.52	0.55	0.59	0.76	0.55	0.55	0.50	1.00	0.55	0.55	0.55	0.56	0.56	0.64	0.54	0.37	0.76	1.00	0.48	0.54	0.59	0.51	0.53
652 (BMP4)	0.52	0.67	0.70	0.34	0.71	0.67	0.74	0.69	0.31	0.64	0.63	0.77	0.58	0.41	0.60	0.70	0.60	0.56	0.60	0.71	0.64	1.00	0.61	0.58	0.67	0.65	0.66	0.77	0.34	0.64	0.63	0.57	0.55	1.00	0.74	0.67	0.68	0.72	0.64	0.64	0.37	0.34	1.00	0.56	0.70	0.65	0.67	0.71
3487 (IGFBP4)	0.52	0.69	0.73	0.26	0.77	0.73	0.98	0.77	0.27	0.82	0.68	0.80	0.60	0.44	0.60	0.77	0.62	0.58	0.62	0.74	0.67	1.00	0.62	0.61	0.71	0.69	0.70	0.79	0.26	0.67	0.70	0.58	0.55	0.74	1.00	0.71	0.73	0.79	0.48	0.62	0.37	0.26	1.00	0.60	0.95	0.66	0.73	0.78
4148 (MATN3)	0.44	0.73	0.65	1.00	0.73	0.65	0.71	0.69	0.78	0.61	0.60	0.70	0.73	0.36	0.57	0.71	0.55	0.47	0.76	0.72	0.62	1.00	0.52	0.54	1.00	0.60	0.64	0.71	1.00	0.82	0.62	0.48	0.55	0.67	0.71	1.00	0.96	0.75	0.48	0.53	0.37	1.00	1.00	0.56	0.71	0.95	0.66	0.74
3371 (TNC)	0.47	0.73	0.67	1.00	0.74	0.69	0.72	0.72	0.68	0.63	0.63	0.71	0.74	0.37	0.59	0.73	0.58	0.50	0.76	0.73	0.64	1.00	0.55	0.56	0.96	0.64	0.66	0.72	1.00	0.82	0.63	0.53	0.56	0.68	0.73	0.96	1.00	0.76	0.48	0.56	0.37	1.00	1.00	0.58	0.73	0.93	0.69	0.75
6383 (SDC2)	0.51	0.69	0.75	0.26	0.80	0.77	0.78	0.80	0.29	0.67	0.68	0.77	0.63	0.41	0.64	0.82	0.67	0.53	0.63	0.78	0.67	1.00	0.60	0.59	0.75	0.73	0.72	0.82	0.26	0.70	0.65	0.59	0.56	0.72	0.79	0.75	0.76	1.00	0.48	0.61	0.37	0.26	1.00	0.68	0.79	0.68	0.77	0.82
54587 (MXRA8)	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.64	0.48	0.48	0.48	0.48	0.22	0.64	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.48	0.64	0.64	0.48	0.48	0.48	0.48	1.00	0.48	0.28	0.48	0.48	0.38	0.48	0.64	0.48	0.48
7076 (TIMP1)	0.44	0.63	0.75	0.26	0.61	0.61	0.62	0.56	0.24	0.64	0.59	0.65	0.54	0.33	0.58	0.57	0.78	0.59	0.50	0.68	0.57	1.00	0.51	0.54	0.53	0.75	0.61	0.67	0.26	0.52	0.61	0.54	0.54	0.64	0.62	0.53	0.56	0.61	0.48	1.00	0.37	0.26	1.00	0.50	0.60	0.52	0.54	0.60
10970 (CKAP4)	1.00	0.37	0.75	0.16	0.37	0.37	0.37	0.37	0.21	0.37	1.00	0.37	0.37	0.21	0.75	0.37	0.37	0.37	0.37	0.37	0.37	0.37	0.37	1.00	0.37	0.37	0.37	0.37	0.16	0.37	0.37	0.37	0.37	0.37	0.37	0.37	0.37	0.37	0.28	0.37	1.00	0.16	0.37	0.55	0.37	0.37	1.00	0.37
64856 (VWA1)	0.26	1.00	0.26	1.00	0.26	0.26	0.26	0.26	1.00	0.26	0.26	0.26	1.00	0.14	0.34	0.26	0.26	0.26	1.00	0.26	0.26	0.26	0.26	0.26	1.00	0.26	0.26	0.26	1.00	0.82	0.26	0.26	0.76	0.34	0.26	1.00	1.00	0.26	0.48	0.26	0.16	1.00	0.26	0.21	0.26	1.00	0.26	0.26
10232 (MSLN)	1.00	1.00	1.00	0.26	1.00	1.00	1.00	1.00	0.34	1.00	1.00	1.00	1.00	0.50	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.26	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	0.48	1.00	0.37	0.26	1.00	0.82	1.00	1.00	1.00	1.00
8614 (STC2)	0.44	0.59	0.67	0.21	0.63	0.58	0.60	0.60	0.24	0.52	0.60	0.59	0.48	0.32	0.54	0.62	0.54	0.43	0.48	0.68	0.55	0.82	0.56	0.49	0.56	0.54	0.55	0.70	0.21	0.53	0.54	0.44	0.48	0.56	0.60	0.56	0.58	0.68	0.38	0.50	0.55	0.21	0.82	1.00	0.60	0.52	0.67	0.63
3488 (IGFBP5)	0.51	0.66	0.70	0.26	0.77	0.73	0.94	0.75	0.27	0.85	0.66	0.74	0.59	0.39	0.60	0.77	0.62	0.53	0.62	0.74	0.66	1.00	0.58	0.58	0.71	0.69	0.70	0.74	0.26	0.67	0.71	0.58	0.54	0.70	0.95	0.71	0.73	0.79	0.48	0.60	0.37	0.26	1.00	0.60	1.00	0.66	0.73	0.83
3912 (LAMB1)	0.44	0.73	0.63	1.00	0.67	0.59	0.66	0.62	0.87	0.59	0.57	0.65	0.73	0.32	0.57	0.64	0.54	0.47	0.76	0.68	0.60	1.00	0.52	0.54	0.95	0.56	0.60	0.67	1.00	0.79	0.60	0.47	0.59	0.65	0.66	0.95	0.93	0.68	0.64	0.52	0.37	1.00	1.00	0.52	0.66	1.00	0.59	0.67
3956 (LGALS1)	0.57	0.63	0.75	0.26	0.75	0.68	0.73	0.72	0.29	0.62	0.79	0.71	0.54	0.38	0.64	0.74	0.57	0.48	0.56	0.73	0.63	1.00	0.53	0.64	0.66	0.63	0.66	0.72	0.26	0.61	0.62	0.50	0.51	0.67	0.73	0.66	0.69	0.77	0.48	0.54	1.00	0.26	1.00	0.67	0.73	0.59	1.00	0.76
10272 (FSTL3)	0.52	0.69	0.71	0.26	0.79	0.76	0.77	0.81	0.29	0.70	0.67	0.76	0.60	0.49	0.61	0.81	0.62	0.53	0.62	0.76	0.68	1.00	0.59	0.59	0.74	0.72	0.75	0.76	0.26	0.69	0.67	0.58	0.53	0.71	0.78	0.74	0.75	0.82	0.48	0.60	0.37	0.26	1.00	0.63	0.83	0.67	0.76	1.00

Association with High Altitude

Protein Official symbol	Source Organism	Tissue of Expression	Level of hypoxia	Altitude	Duration of experiment	Level of expression	Fold change	Experiment details	geographical location	ethnicity of the patients	Control group	Control (Fold change)	Reference (PMID)
CYR61	Toad	Liver	-	3464 m	33 day	downregulated	-2.395025872	RNA-seq	Tibetan Plateau	Asiatic toad	1	Zoige (High altitute Toad) Vs Chengdu (Low altitude toad) -	28673260
CYR61	Toad	Heart	-	3464 m	33 day	downregulated	-2.928782676	RNA-seq	Tibetan Plateau	Asiatic toad	1	Zoige (High altitute Toad) Vs Chengdu (Low altitude toad) -	28673260

Association with TF

TF	TF Entrez	Gene	Gene Entrez	Type	PMID	Database
JUND	3727	CYR61	3491	proximal_filtered	22955619	TRANSFAC
E2F1	1869	CYR61	3491	proximal_filtered	22955619	TRANSFAC
BCL11A	53335	CYR61	3491	proximal_filtered	22955619	TRANSFAC
TAF7	6879	CYR61	3491	proximal_filtered	22955619	TRANSFAC
GLI1	2735	CYR61	3491	Unknown	10022513	TRUSST
STAT3	6774	CYR61	3491	Unknown	10022513	TRUSST

Association with miRNA

miRTarBase ID	miRNA	Species (miRNA)	Protein Official Symbol	Human Entrez ID	Species (Target Gene)	Experiments	Support Type	References (PMID)
MIRT001764	hsa-miR-30a-3p	Homo sapiens	CYR61	3491	Homo sapiens	Luciferase reporter assay//qRT-PCR//Western blot//Western blot;qRT-PCR	Functional MTI	16239240
MIRT005484	hsa-miR-155-5p	Homo sapiens	CYR61	3491	Homo sapiens	Luciferase reporter assay//qRT-PCR//Western blot	Functional MTI	20452491
MIRT005484	hsa-miR-155-5p	Homo sapiens	CYR61	3491	Homo sapiens	Microarray//qRT-PCR//Luciferase reporter assay//Western blot	Functional MTI	24705102
MIRT005484	hsa-miR-155-5p	Homo sapiens	CYR61	3491	Homo sapiens	Proteomics	Functional MTI (Weak)	18668040
MIRT006935	hsa-miR-205-5p	Homo sapiens	CYR61	3491	Homo sapiens	Western blot	Functional MTI	23056551
MIRT023099	hsa-miR-124-3p	Homo sapiens	CYR61	3491	Homo sapiens	Microarray	Functional MTI (Weak)	18668037
MIRT030115	hsa-miR-26b-5p	Homo sapiens	CYR61	3491	Homo sapiens	Microarray	Functional MTI (Weak)	19088304
MIRT054848	hsa-miR-22-3p	Homo sapiens	CYR61	3491	Homo sapiens	Luciferase reporter assay//qRT-PCR//Western blot	Functional MTI	24449575
MIRT080736	hsa-miR-622	Homo sapiens	CYR61	3491	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT437968	hsa-miR-634	Homo sapiens	CYR61	3491	Homo sapiens	Microarray//qRT-PCR//Luciferase reporter assay//Western blot	Functional MTI	24705102
MIRT438171	hsa-miR-100-5p	Homo sapiens	CYR61	3491	Homo sapiens	ELISA//Luciferase reporter assay//qRT-PCR//Western blot	Functional MTI	24317814
MIRT538206	hsa-miR-455-3p	Homo sapiens	CYR61	3491	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538209	hsa-miR-3622b-3p	Homo sapiens	CYR61	3491	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538210	hsa-miR-3622a-3p	Homo sapiens	CYR61	3491	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538211	hsa-miR-5586-3p	Homo sapiens	CYR61	3491	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538214	hsa-miR-647	Homo sapiens	CYR61	3491	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538223	hsa-miR-1204	Homo sapiens	CYR61	3491	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538202	hsa-miR-4652-3p	Homo sapiens	CYR61	3491	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538217	hsa-miR-142-3p	Homo sapiens	CYR61	3491	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538203	hsa-miR-6516-5p	Homo sapiens	CYR61	3491	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538208	hsa-miR-29a-5p	Homo sapiens	CYR61	3491	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538218	hsa-miR-630	Homo sapiens	CYR61	3491	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538216	hsa-miR-515-5p	Homo sapiens	CYR61	3491	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538207	hsa-miR-302a-5p	Homo sapiens	CYR61	3491	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538213	hsa-miR-3912-5p	Homo sapiens	CYR61	3491	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538212	hsa-miR-3591-5p	Homo sapiens	CYR61	3491	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538219	hsa-miR-6762-3p	Homo sapiens	CYR61	3491	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538205	hsa-miR-1303	Homo sapiens	CYR61	3491	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538225	hsa-miR-548l	Homo sapiens	CYR61	3491	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538220	hsa-miR-604	Homo sapiens	CYR61	3491	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538221	hsa-miR-20a-3p	Homo sapiens	CYR61	3491	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538222	hsa-miR-5695	Homo sapiens	CYR61	3491	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538224	hsa-miR-3973	Homo sapiens	CYR61	3491	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538204	hsa-miR-4743-3p	Homo sapiens	CYR61	3491	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620
MIRT538215	hsa-miR-519e-5p	Homo sapiens	CYR61	3491	Homo sapiens	PAR-CLIP	Functional MTI (Weak)	22012620

Gene Ontology

ID	GO ID	GO Term	GO Type
3491	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	GOTERM_BP_DIRECT
3491	GO:0060548	negative regulation of cell death	GOTERM_BP_DIRECT
3491	GO:2000304	positive regulation of ceramide biosynthetic process	GOTERM_BP_DIRECT
3491	GO:0043066	negative regulation of apoptotic process	GOTERM_BP_DIRECT
3491	GO:0003181	atrioventricular valve morphogenesis	GOTERM_BP_DIRECT
3491	GO:0007155	cell adhesion	GOTERM_BP_DIRECT
3491	GO:0010811	positive regulation of cell-substrate adhesion	GOTERM_BP_DIRECT
3491	GO:0045669	positive regulation of osteoblast differentiation	GOTERM_BP_DIRECT
3491	GO:0008283	cell proliferation	GOTERM_BP_DIRECT
3491	GO:0060716	labyrinthine layer blood vessel development	GOTERM_BP_DIRECT
3491	GO:0002041	intussusceptive angiogenesis	GOTERM_BP_DIRECT
3491	GO:0033690	positive regulation of osteoblast proliferation	GOTERM_BP_DIRECT
3491	GO:0050840	cell adhesion molecule binding	GOTERM_MF_DIRECT
3491	GO:0031012	extracellular matrix	GOTERM_CC_DIRECT
3491	GO:0001649	osteoblast differentiation	GOTERM_BP_DIRECT
3491	GO:0003278	apoptotic process involved in heart morphogenesis	GOTERM_BP_DIRECT
3491	GO:0030513	positive regulation of BMP signaling pathway	GOTERM_BP_DIRECT
3491	GO:0044319	wound healing	GOTERM_BP_DIRECT
3491	GO:0060710	chorio-allantoic fusion	GOTERM_BP_DIRECT
3491	GO:0005520	collagen binding	GOTERM_MF_DIRECT
3491	GO:0045860	positive regulation of protein kinase activity	GOTERM_BP_DIRECT
3491	GO:0005578	proteinaceous extracellular matrix	GOTERM_CC_DIRECT
3491	GO:0007267	cell-cell signaling	GOTERM_BP_DIRECT
3491	GO:0045597	positive regulation of cell differentiation	GOTERM_BP_DIRECT
3491	GO:0060413	atrial septum morphogenesis	GOTERM_BP_DIRECT
3491	GO:0001934	positive regulation of protein phosphorylation	GOTERM_BP_DIRECT
3491	GO:0030198	extracellular matrix organization	GOTERM_BP_DIRECT
3491	GO:0010518	positive regulation of phospholipase activity	GOTERM_BP_DIRECT
3491	GO:0070372	regulation of ERK1 and ERK2 cascade	GOTERM_BP_DIRECT
3491	GO:0000166	nucleotide binding	GOTERM_MF_DIRECT
3491	GO:0030335	positive regulation of cell migration	GOTERM_BP_DIRECT
3491	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	GOTERM_BP_DIRECT
3491	GO:0061036	positive regulation of cartilage development	GOTERM_BP_DIRECT
3491	GO:0060591	chondroblast differentiation	GOTERM_BP_DIRECT
3491	GO:0005178	vascular endothelial growth factor receptor binding	GOTERM_MF_DIRECT
3491	GO:0072593	reactive oxygen species metabolic process	GOTERM_BP_DIRECT
3491	GO:0008201	heparin binding	GOTERM_MF_DIRECT
3491	GO:0005576	extracellular region	GOTERM_CC_DIRECT
3491	GO:0001558	regulation of cell growth	GOTERM_BP_DIRECT
3491	GO:0003281	ventricular septum development	GOTERM_BP_DIRECT
3491	GO:0006935	chemotaxis	GOTERM_BP_DIRECT
3491	GO:0009653	anatomical structure morphogenesis	GOTERM_BP_DIRECT

Pathways

Human Entrez ID	KEGG ID	KEGG Term

Association with Disease

Protein Official Symbol	Human Entrez ID	Disease Name	Disease Id	Disease Semantic Type	Semantic score	DSI	DPI	Disease Type
CYR61	3491	Rheumatoid Arthritis	C0003873	Disease or Syndrome	0.38	0.514	0.655	disease
CYR61	3491	Malignant neoplasm of lung	C0242379	Neoplastic Process	0.31	0.514	0.655	disease
CYR61	3491	Liver carcinoma	C2239176	Neoplastic Process	0.35	0.514	0.655	disease
CYR61	3491	Lung Neoplasms	C0024121	Neoplastic Process	0.31	0.514	0.655	group

Association with Drug

Protein Official Symbol	Human Entrez ID	drug_claim_primary_name	drug_name	drug_chembl_id	interaction_types
CYR61	3491	ANTISENSE OLIGONUCLEOTIDES	None	None	None
CYR61	3491	HYPOTENSIVE AGENTS	None	None	None
CYR61	3491	INTERLEUKIN-8	CHEMBL411250	CHEMBL411250	None